Mus musculus

0 known processes

Tlr8

toll-like receptor 8

Tlr8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense response to other organismGO:00985421970.745
Human Mouse
detection of yeastGO:000187920.738
innate immune responseGO:00450871570.550
Human Mouse
detection of fungusGO:001604620.535
activation of innate immune responseGO:0002218560.473
Mouse
immune response activating signal transductionGO:00027571160.451
Mouse
regulation of innate immune responseGO:0045088910.442
Human Mouse
regulation of cell activationGO:00508652890.437
Mouse
cytokine productionGO:00018163190.421
Human Mouse
positive regulation of innate immune responseGO:0045089800.396
Human Mouse
immune effector processGO:00022523210.388
Human Mouse
activation of immune responseGO:00022531380.364
Mouse
inflammatory responseGO:00069542440.356
Mouse
regulation of defense responseGO:00313472330.301
Human Mouse
regulation of establishment of protein localizationGO:00702011810.301
Mouse
detection of external biotic stimulusGO:009858190.300
regulation of secretionGO:00510462740.298
Mouse
sequestering of metal ionGO:0051238190.289
positive regulation of immune effector processGO:00026991070.275
Mouse
immune response regulating cell surface receptor signaling pathwayGO:0002768800.271
Mouse
immune response regulating signaling pathwayGO:00027641250.264
Mouse
divalent inorganic cation transportGO:00725111780.263
immune response activating cell surface receptor signaling pathwayGO:0002429720.262
Mouse
detection of bacteriumGO:001604570.248
leukocyte activation involved in immune responseGO:00023661260.246
Mouse
regulation of secretion by cellGO:19035302490.242
Mouse
cellular amino acid metabolic processGO:00065201030.237
cation transportGO:00068123990.234
positive regulation of defense responseGO:00313491240.229
Human Mouse
negative regulation of immune system processGO:00026832090.219
lymphocyte proliferationGO:00466511640.199
Mouse
regulation of cell migrationGO:00303342190.198
Mouse
t cell activationGO:00421102890.190
regulation of vesicle mediated transportGO:00606271390.186
regulation of cytokine productionGO:00018172660.182
Human Mouse
negative regulation of immune effector processGO:0002698550.175
cellular response to molecule of bacterial originGO:0071219830.174
Mouse
leukocyte chemotaxisGO:0030595690.174
cellular response to lipopolysaccharideGO:0071222770.172
Mouse
negative regulation of serotonin secretionGO:001406320.171
detection of other organismGO:009854380.170
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.169
leukocyte migrationGO:00509001240.167
Mouse
sequestering of calcium ionGO:0051208180.161
defense response to bacteriumGO:00427421190.152
Mouse
cellular amine metabolic processGO:0044106440.148
regulation of cytokine secretionGO:0050707610.148
Mouse
defense response to gram positive bacteriumGO:0050830500.147
Mouse
regulation of leukocyte mediated immunityGO:00027031040.145
membrane organizationGO:00610242450.144
leukocyte mediated immunityGO:00024431740.144
innate immune response activating signal transductionGO:0002758500.142
Mouse
release of sequestered calcium ion into cytosolGO:0051209420.142
detection of biotic stimulusGO:0009595100.140
cellular response to biotic stimulusGO:0071216920.139
Mouse
divalent metal ion transportGO:00708381720.136
regulation of lymphocyte proliferationGO:00506701170.134
Mouse
regulation of t cell proliferationGO:0042129920.132
humoral immune responseGO:0006959570.132
positive regulation of cellular amino acid metabolic processGO:004576430.131
cytokine secretionGO:0050663720.130
Mouse
cell activation involved in immune responseGO:00022631260.129
Mouse
negative regulation of leukocyte mediated immunityGO:0002704290.128
regulation of protein secretionGO:0050708820.126
Mouse
cell chemotaxisGO:0060326810.125
chemotaxisGO:00069352470.125
cellular ketone metabolic processGO:0042180840.123
regulation of cell motilityGO:20001452360.123
Mouse
positive regulation of phagocytosisGO:0050766260.122
phagocytosisGO:0006909660.120
cellular response to cytokine stimulusGO:00713451890.119
g protein coupled receptor signaling pathwayGO:00071862430.117
calcium ion homeostasisGO:00550741270.114
cation homeostasisGO:00550802120.110
tumor necrosis factor superfamily cytokine productionGO:0071706510.108
Mouse
regulation of cellular amine metabolic processGO:0033238200.107
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.106
regulation of protein localizationGO:00328802310.102
Mouse
negative regulation of leukocyte proliferationGO:0070664460.102
positive regulation of toll like receptor 9 signaling pathwayGO:003416520.102
keratinocyte migrationGO:005154630.095
regulation of ion transportGO:00432692150.094
cytokine biosynthetic processGO:0042089680.094
Human Mouse
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.092
Mouse
regulation of cytokine biosynthetic processGO:0042035590.092
Human Mouse
amine metabolic processGO:0009308450.092
positive regulation of cytokine productionGO:00018191740.091
Human Mouse
t cell proliferationGO:00420981200.091
regulation of leukocyte proliferationGO:00706631210.090
Mouse
negative regulation of t cell proliferationGO:0042130380.089
protein secretionGO:00093061110.088
Mouse
positive regulation of tumor necrosis factor biosynthetic processGO:004253580.086
Mouse
blood vessel morphogenesisGO:00485142850.085
neutrophil chemotaxisGO:0030593360.085
endocytosisGO:00068971680.085
immunoglobulin transcytosis in epithelial cellsGO:000241420.085
angiogenesisGO:00015252010.085
positive regulation of cellular amine metabolic processGO:003324050.085
serotonin secretion by mast cellGO:000255210.084
regulation of response to woundingGO:19030341890.083
Mouse
regulation of system processGO:00440572000.083
regulation of vasculature developmentGO:1901342880.082
regulation of angiogenesisGO:0045765810.082
regulation of ion homeostasisGO:2000021640.082
response to molecule of bacterial originGO:00022371430.079
Mouse
regulation of protein transportGO:00512231630.079
Mouse
calcium mediated signalingGO:0019722460.079
cytokine metabolic processGO:0042107710.078
Human Mouse
regulation of inflammatory responseGO:00507271470.077
Mouse
regulation of lymphocyte activationGO:00512492400.077
Mouse
adaptive immune responseGO:00022501550.077
regulation of tumor necrosis factor productionGO:0032680490.076
Mouse
second messenger mediated signalingGO:0019932730.074
metal ion homeostasisGO:00550651890.072
eosinophil degranulationGO:004330810.071
cellular homeostasisGO:00197252400.071
positive regulation of monocyte chemotaxisGO:009002620.071
regulation of cytoplasmic transportGO:19036491120.071
oxidation reduction processGO:00551143420.071
regulation of cellular ketone metabolic processGO:0010565660.070
cellular ion homeostasisGO:00068731650.069
cellular response to organonitrogen compoundGO:00714171450.068
Mouse
positive regulation of cell activationGO:00508671580.068
Mouse
cellular divalent inorganic cation homeostasisGO:00725031270.068
negative regulation of mast cell degranulationGO:004330540.067
fat cell differentiationGO:00454441600.065
positive regulation of cytokine biosynthetic processGO:0042108400.064
Human Mouse
interleukin 6 productionGO:0032635580.064
Mouse
alpha beta t cell activationGO:0046631910.063
leukocyte differentiationGO:00025213420.062
peptidyl amino acid modificationGO:00181933360.061
cytosolic calcium ion transportGO:0060401480.061
myeloid leukocyte migrationGO:0097529570.059
negative regulation of molecular functionGO:00440922580.059
regulation of calcium ion transport into cytosolGO:0010522310.059
positive regulation of angiogenesisGO:0045766460.059
cellular calcium ion homeostasisGO:00068741190.058
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.058
Mouse
maintenance of locationGO:0051235890.057
negative regulation of cellular protein metabolic processGO:00322692470.057
regulation of lymphocyte mediated immunityGO:0002706840.057
regulation of cellular amino acid metabolic processGO:000652150.057
antigen processing and presentationGO:0019882470.056
positive regulation of homeostatic processGO:0032846640.056
calcium ion transportGO:00068161590.056
myeloid cell differentiationGO:00300992330.055
cellular chemical homeostasisGO:00550822150.055
regulation of calcium ion transportGO:0051924690.055
positive regulation of secretion by cellGO:19035321140.054
Mouse
lymphocyte mediated immunityGO:00024491390.054
regulation of adaptive immune responseGO:0002819900.054
toll like receptor 9 signaling pathwayGO:003416260.054
regulation of reactive oxygen species metabolic processGO:2000377400.054
negative regulation of lymphocyte proliferationGO:0050672450.054
regulation of mapk cascadeGO:00434082480.054
Mouse
calcium ion transport into cytosolGO:0060402480.053
negative regulation of adaptive immune responseGO:0002820250.053
positive regulation of calcium ion transport into cytosolGO:001052490.053
negative regulation of cell activationGO:00508661110.051
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.051
positive regulation of lymphocyte mediated immunityGO:0002708620.050
regulation of phagocytosisGO:0050764330.050
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.050
circulatory system processGO:00030131970.049
t helper 17 cell chemotaxisGO:003570510.049
divalent inorganic cation homeostasisGO:00725071380.049
cellular metal ion homeostasisGO:00068751510.048
negative regulation of lymphocyte activationGO:0051250910.048
negative regulation of phosphorus metabolic processGO:00105631840.048
Mouse
regulation of intracellular transportGO:00323861590.047
positive regulation of cell migrationGO:00303351090.046
Mouse
i kappab kinase nf kappab signalingGO:0007249850.046
Human Mouse
negative regulation of intracellular signal transductionGO:19025321670.045
Mouse
blood circulationGO:00080151950.044
regulation of humoral immune responseGO:0002920220.044
regulation of metal ion transportGO:00109591060.044
negative regulation of phosphate metabolic processGO:00459361840.044
Mouse
extracellular matrix organizationGO:00301981470.043
cytoplasmic transportGO:00164822340.043
negative regulation of secretion by cellGO:1903531540.042
negative regulation of phagocytosisGO:005076540.042
organic cyclic compound catabolic processGO:19013612950.041
regulation of t cell activationGO:00508631700.041
b cell proliferationGO:0042100530.041
Mouse
granulocyte chemotaxisGO:0071621390.041
reactive oxygen species metabolic processGO:0072593840.041
positive regulation of protein transportGO:0051222930.041
Mouse
purine containing compound metabolic processGO:00725213110.040
purine ribonucleotide metabolic processGO:00091502900.040
organic anion transportGO:00157111370.040
germ cell developmentGO:00072811850.040
positive regulation of reactive oxygen species biosynthetic processGO:190342820.040
nucleobase containing small molecule metabolic processGO:00550863520.039
small gtpase mediated signal transductionGO:0007264970.039
apoptotic signaling pathwayGO:00971903060.039
cell growthGO:00160491300.039
nucleotide metabolic processGO:00091173320.039
regulation of transferase activityGO:00513382630.039
Mouse
antigen receptor mediated signaling pathwayGO:0050851640.039
serotonin secretion involved in inflammatory responseGO:000244240.038
cellular response to hormone stimulusGO:00328701500.038
detection of molecule of bacterial originGO:003249020.038
positive regulation of calcium ion transportGO:0051928270.038
toll like receptor 7 signaling pathwayGO:003415440.038
anion transportGO:00068201770.038
interleukin 12 productionGO:0032615320.038
Mouse
regulation of antigen receptor mediated signaling pathwayGO:0050854290.038
ameboidal type cell migrationGO:00016671280.037
regulation of endocytosisGO:0030100690.037
negative regulation of phosphorylationGO:00423261660.037
Mouse
positive regulation of response to woundingGO:1903036660.037
Mouse
regulation of neuron differentiationGO:00456642810.036
negative regulation of t cell activationGO:0050868650.036
tumor necrosis factor biosynthetic processGO:0042533100.036
Mouse
positive regulation of t cell costimulationGO:200052520.036
t cell differentiationGO:00302171740.036
sensory perceptionGO:00076002450.036
axonogenesisGO:00074092740.036
negative regulation of synapse assemblyGO:005196430.036
reactive nitrogen species metabolic processGO:200105700.036
response to organonitrogen compoundGO:00102432460.036
Mouse
extrinsic apoptotic signaling pathwayGO:00971911260.036
mapk cascadeGO:00001652810.036
Mouse
rho protein signal transductionGO:0007266320.035
macromolecule catabolic processGO:00090572810.035
positive regulation of leukocyte mediated immunityGO:0002705700.035
transmission of nerve impulseGO:0019226760.035
cytosolic calcium ion homeostasisGO:0051480700.034
granulocyte migrationGO:0097530430.034
negative regulation of t cell mediated immunityGO:000271090.033
negative regulation of protein metabolic processGO:00512482820.033
antibacterial peptide biosynthetic processGO:000278020.033
negative regulation of cellular component organizationGO:00511291940.033
positive regulation of cytokine secretionGO:0050715410.032
Mouse
t cell mediated immunityGO:0002456500.032
tumor necrosis factor productionGO:0032640500.032
Mouse
mature dendritic cell differentiationGO:009702930.032
ion transmembrane transportGO:00342203610.032
positive regulation of protein modification processGO:00314012990.031
Mouse
positive regulation of ion transportGO:0043270650.031
negative regulation of cellular amino acid metabolic processGO:004576300.031
positive regulation of tumor necrosis factor productionGO:0032760300.031
Mouse
protein kinase b signalingGO:0043491740.031
negative regulation of cytokine productionGO:0001818840.031
Mouse
positive regulation of t cell receptor signaling pathwayGO:005086240.031
regulation of exocytosisGO:0017157610.031
regulation of interleukin 12 productionGO:0032655300.030
Mouse
regulation of membrane potentialGO:00423911920.030
response to growth factorGO:00708481980.030
positive regulation of t cell activationGO:00508701010.030
myeloid cell activation involved in immune responseGO:0002275340.030
leukocyte proliferationGO:00706611720.030
Mouse
exocytosisGO:00068871210.030
regulation of fat cell differentiationGO:0045598810.030
heterocycle catabolic processGO:00467002800.030
negative regulation of homeostatic processGO:0032845710.030
regulation of cellular catabolic processGO:00313292420.030
cell type specific apoptotic processGO:00972852680.029
action potentialGO:0001508780.029
positive regulation of interleukin 18 productionGO:003274120.029
Mouse
inorganic ion transmembrane transportGO:00986602340.029
single organismal cell cell adhesionGO:00163371310.029
regulation of kinase activityGO:00435492490.029
Mouse
positive regulation of cell motilityGO:20001471160.029
Mouse
transmembrane transportGO:00550854120.029
regulation of immunoglobulin mediated immune responseGO:0002889370.029
glycoprotein biosynthetic processGO:0009101890.028
nitrogen compound transportGO:00717052710.028
positive regulation of adaptive immune responseGO:0002821610.028
negative regulation of secretionGO:0051048610.028
hematopoietic progenitor cell differentiationGO:00022441430.028
response to lipopolysaccharideGO:00324961280.028
Mouse
positive regulation of stress activated mapk cascadeGO:0032874480.028
Mouse
negative regulation of cell proliferationGO:00082852960.027
regulation of lipid metabolic processGO:00192161180.027
posttranscriptional regulation of gene expressionGO:00106081550.027
protein catabolic processGO:00301632210.027
cell recognitionGO:0008037830.027
organophosphate biosynthetic processGO:00904071220.027
regulation of homeostatic processGO:00328441820.027
regulation of organelle organizationGO:00330432890.027
antibacterial peptide productionGO:000277820.027
mast cell activation involved in immune responseGO:0002279200.026
negative regulation of eosinophil degranulationGO:004331010.026
lymphocyte differentiationGO:00300982420.026
cell adhesionGO:00071553290.026
response to peptide hormoneGO:00434341270.026
pattern recognition receptor signaling pathwayGO:0002221470.026
Mouse
positive regulation of vasoconstrictionGO:004590740.026
skeletal system developmentGO:00015013560.026
regulation of monocyte chemotaxisGO:009002530.026
cellular response to growth factor stimulusGO:00713631970.026
gliogenesisGO:00420631410.025
detection of stimulusGO:0051606840.025
positive regulation of intracellular transportGO:0032388700.025
positive regulation of endocytosisGO:0045807420.025
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.025
positive regulation of lymphocyte proliferationGO:0050671700.025
Mouse
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.025
positive regulation of t cell extravasationGO:200040920.025
activation of mapk activity involved in innate immune responseGO:003541920.025
response to acid chemicalGO:00011011110.025
negative regulation of regulated secretory pathwayGO:190330670.025
aromatic compound catabolic processGO:00194392860.025
regulation of cell cycleGO:00517262810.025
nucleoside phosphate metabolic processGO:00067533380.024
protein processingGO:00164851630.024
interferon beta biosynthetic processGO:004535040.024
Human Mouse
response to organic cyclic compoundGO:00140701980.024
regulation of t cell mediated immunityGO:0002709340.024
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.024
regulation of immunological synapse formationGO:200052020.024
multicellular organismal signalingGO:0035637910.024
peptidyl tyrosine phosphorylationGO:00181081430.024
positive regulation of cell deathGO:00109422240.024
positive regulation of map kinase activityGO:0043406840.024
Mouse
carbohydrate metabolic processGO:00059752300.024
ras protein signal transductionGO:0007265770.024
cellular macromolecule catabolic processGO:00442652060.024
regulation of protein kinase b signalingGO:0051896560.024
defense response to virusGO:0051607680.024
Human
helper t cell chemotaxisGO:003570410.024
mast cell activationGO:0045576270.024
negative regulation of response to woundingGO:1903035770.024
purine ribonucleoside triphosphate metabolic processGO:00092052200.024
organic hydroxy compound transportGO:0015850930.023
inorganic cation transmembrane transportGO:00986622070.023
monocyte extravasationGO:003569620.023
response to peptideGO:19016521360.023
regulation of interferon gamma productionGO:0032649570.023
Human Mouse
regulation of tumor necrosis factor biosynthetic processGO:0042534100.023
Mouse
b cell activationGO:00421131610.023
Mouse
glycosyl compound catabolic processGO:19016582060.023
regulation of vascular endothelial growth factor productionGO:0010574130.023
carbohydrate derivative biosynthetic processGO:19011371830.023
regulation of mast cell activationGO:0033003210.023
positive regulation of nervous system developmentGO:00519622210.023
purine nucleotide metabolic processGO:00061633020.023
positive regulation vascular endothelial growth factor productionGO:0010575100.023
protein modification by small protein conjugation or removalGO:00706472070.023
regulation of interleukin 6 productionGO:0032675550.023
Mouse
cartilage developmentGO:00512161400.022
regulation of hormone levelsGO:00108172110.022
digestive system developmentGO:00551232000.022
t cell extravasationGO:007268340.022
regulation of protein kinase activityGO:00458592320.022
Mouse
digestive tract developmentGO:00485651900.022
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.022
positive regulation of secretionGO:00510471300.022
Mouse
response to oxidative stressGO:00069791230.022
carboxylic acid transportGO:00469421000.022
positive regulation of gliogenesisGO:0014015270.022
positive regulation of nucleoside metabolic processGO:0045979910.022
neuronal action potentialGO:0019228540.022
regulation of apoptotic signaling pathwayGO:20012331970.022
regulation of reactive oxygen species biosynthetic processGO:190342620.022
organonitrogen compound biosynthetic processGO:19015661920.021
positive regulation of protein kinase activityGO:00458601440.021
Mouse
regulation of b cell proliferationGO:0030888390.021
Mouse
regulation of t cell costimulationGO:200052320.021
stem cell differentiationGO:00488632680.021
microglial cell activation involved in immune responseGO:000228210.021
myeloid leukocyte activationGO:0002274830.021
positive regulation of interleukin 8 productionGO:003275720.021
Human
stress activated protein kinase signaling cascadeGO:0031098810.021
Mouse
dna metabolic processGO:00062593030.021
regulation of synaptic growth at neuromuscular junctionGO:000858240.021
lipid biosynthetic processGO:00086101790.021
regulation of hematopoietic stem cell migrationGO:200047110.021
regulation of leukocyte differentiationGO:19021051590.021
regulation of natural killer cell activationGO:0032814220.021
regulation of protein processingGO:0070613960.020
negative regulation of intracellular transportGO:0032387380.020
regulation of neutrophil chemotaxisGO:0090022140.020
protein maturationGO:00516041760.020
transforming growth factor beta receptor signaling pathwayGO:0007179710.020
cellular amide metabolic processGO:0043603580.020
b cell activation involved in immune responseGO:0002312500.020
Mouse
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.020
hormone secretionGO:00468791280.020
cellular lipid metabolic processGO:00442553230.020
purine ribonucleoside metabolic processGO:00461282410.020
interspecies interaction between organismsGO:0044419830.020
Mouse
neutrophil migrationGO:1990266370.020
regulation of rho protein signal transductionGO:0035023710.020
eosinophil activation involved in immune responseGO:000227810.020
intracellular protein transportGO:00068862040.020
organic hydroxy compound metabolic processGO:19016152030.020
myeloid leukocyte mediated immunityGO:0002444420.020
production of molecular mediator of immune responseGO:00024401030.020
Mouse
regulation of acute inflammatory responseGO:0002673270.020
negative regulation of protein modification processGO:00314001630.020
antimicrobial peptide productionGO:000277520.020
cellular response to oxidative stressGO:0034599760.019
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.019
neuron apoptotic processGO:00514021420.019
positive regulation of cytoplasmic transportGO:1903651400.019
negative regulation of defense responseGO:0031348770.019
myelinationGO:0042552740.019
immune complex clearanceGO:000243420.019
regulation of proteolysisGO:00301621640.019
positive regulation of leukocyte differentiationGO:1902107860.019
extracellular structure organizationGO:00430621480.019
positive regulation of protein phosphorylationGO:00019342420.019
Mouse
cognitionGO:00508901490.019
cellular response to transforming growth factor beta stimulusGO:0071560880.019
negative regulation of cellular amine metabolic processGO:003323910.019
organophosphate catabolic processGO:00464342320.019
gland developmentGO:00487323300.019
glucan metabolic processGO:0044042320.019
columnar cuboidal epithelial cell differentiationGO:0002065820.019
ribonucleotide metabolic processGO:00092592910.019
positive regulation of dendritic cell chemotaxisGO:200051010.019
positive regulation of cell developmentGO:00107202370.018
toll like receptor signaling pathwayGO:0002224380.018
Mouse
interleukin 18 productionGO:003262140.018
Mouse
phosphatidylinositol 3 kinase signalingGO:0014065360.018
vasoconstrictionGO:0042310270.018
generation of precursor metabolites and energyGO:00060911030.018
negative regulation of leukocyte degranulationGO:004330170.018
b cell differentiationGO:0030183780.018
regulation of gliogenesisGO:0014013500.018
serotonin production involved in inflammatory responseGO:000235140.018
energy derivation by oxidation of organic compoundsGO:0015980770.018
vascular endothelial growth factor productionGO:0010573130.018
cellular nitrogen compound catabolic processGO:00442702800.018
positive regulation of monocyte extravasationGO:200043910.018
heart processGO:0003015940.018
macrophage chemotaxisGO:0048246140.018
anatomical structure homeostasisGO:00602491450.018
Mouse
cytokine mediated signaling pathwayGO:00192211150.018
ribonucleoside triphosphate catabolic processGO:00092031990.018
cellular carbohydrate metabolic processGO:00442621190.018
regulation of neuron deathGO:19012141340.018
cellular response to peptide hormone stimulusGO:0071375920.018
connective tissue developmentGO:00614481790.017
eosinophil mediated immunityGO:000244710.017
cation transmembrane transportGO:00986552660.017
regulation of protein serine threonine kinase activityGO:00719001570.017
Mouse
organic acid transportGO:00158491010.017
purine nucleoside triphosphate catabolic processGO:00091462030.017
peptide metabolic processGO:0006518460.017
ensheathment of neuronsGO:0007272760.017
epithelial cell migrationGO:0010631630.017
vascular process in circulatory systemGO:0003018620.017
cell substrate adhesionGO:00315891300.017
regulation of map kinase activityGO:00434051200.017
Mouse
purine ribonucleotide catabolic processGO:00091542080.017
detection of peptidoglycanGO:003249910.017
kidney developmentGO:00018222130.017
lipopolysaccharide metabolic processGO:000865320.017
positive regulation of interferon alpha productionGO:003272740.017
Human Mouse
glucose homeostasisGO:00425931280.017
immunoglobulin mediated immune responseGO:0016064690.017
epithelium migrationGO:0090132630.016
protein modification by small protein conjugationGO:00324461870.016
nucleoside phosphate catabolic processGO:19012922220.016
signal transduction in absence of ligandGO:0038034550.016
regulation of b cell mediated immunityGO:0002712370.016
cellular response to peptidoglycanGO:007122440.016
Mouse
organelle assemblyGO:00709251770.016
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.016
negative regulation of protein phosphorylationGO:00019331260.016
positive regulation of glial cell differentiationGO:0045687210.016
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193200.016
inositol lipid mediated signalingGO:0048017410.016
body fluid secretionGO:0007589530.016
symbiosis encompassing mutualism through parasitismGO:0044403830.016
Mouse
purinergic nucleotide receptor signaling pathwayGO:003559030.016
transepithelial chloride transportGO:003032140.016
epithelial cell proliferationGO:00506731740.016
g protein coupled purinergic nucleotide receptor signaling pathwayGO:003558910.016
epidermis developmentGO:00085441870.016
regulation of calcium mediated signalingGO:0050848190.016
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.016
striated muscle tissue developmentGO:00147062930.016
positive regulation of erk1 and erk2 cascadeGO:0070374470.016
Mouse
reactive oxygen species biosynthetic processGO:190340980.016
response to molecule of fungal originGO:000223840.016
Mouse
muscle cell differentiationGO:00426922610.016
cellular response to peptideGO:1901653920.016
positive regulation of immunological synapse formationGO:200052210.016
cellular response to lipidGO:00713961450.016
Mouse
response to yeastGO:000187860.016
regulation of monocyte extravasationGO:200043720.015

Tlr8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
viral infectious diseaseDOID:93400.050
human immunodeficiency virus infectious diseaseDOID:52600.050
disease by infectious agentDOID:005011700.050
acquired immunodeficiency syndromeDOID:63500.050
immune system diseaseDOID:291400.030
disease of anatomical entityDOID:700.030
organ system cancerDOID:005068600.026
cancerDOID:16200.026
disease of cellular proliferationDOID:1456600.026
nervous system diseaseDOID:86300.023
disease of metabolismDOID:001466700.020
eye diseaseDOID:561400.018
sensory system diseaseDOID:005015500.018
eye and adnexa diseaseDOID:149200.018