Mus musculus

100 known processes

Tdg

thymine DNA glycosylase

(Aliases: JZA-3,Jza1,E130317C12Rik)

Tdg biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mrna metabolic processGO:0016071840.141
microtubule cytoskeleton organizationGO:00002261570.126
posttranscriptional regulation of gene expressionGO:00106081550.122
nitrogen compound transportGO:00717052710.122
nucleobase containing small molecule metabolic processGO:00550863520.121
dna repairGO:00062811070.118
chromatin modificationGO:00165681870.116
transcription coupled nucleotide excision repairGO:000628320.104
glycosyl compound metabolic processGO:19016572460.100
nucleoside triphosphate metabolic processGO:00091412300.098
aromatic compound catabolic processGO:00194392860.092
organophosphate biosynthetic processGO:00904071220.091
cellular macromolecule catabolic processGO:00442652060.087
mrna splicing via spliceosomeGO:0000398430.086
dna dealkylationGO:0035510110.084
pyrimidine containing compound metabolic processGO:0072527110.083
cellular amino acid metabolic processGO:00065201030.079
cytoplasmic transportGO:00164822340.079
nucleoside metabolic processGO:00091162460.078
mrna processingGO:0006397630.077
nucleoside phosphate metabolic processGO:00067533380.077
chromatin organizationGO:00063252060.068
pyrimidine nucleoside metabolic processGO:000621320.066
ribonucleoside metabolic processGO:00091192450.065
purine nucleotide metabolic processGO:00061633020.064
negative regulation of molecular functionGO:00440922580.064
pyrimidine ribonucleoside metabolic processGO:004613120.062
negative regulation of protein phosphorylationGO:00019331260.062
cellular nitrogen compound catabolic processGO:00442702800.061
chemotaxisGO:00069352470.061
nucleotide biosynthetic processGO:0009165780.060
ribonucleotide metabolic processGO:00092592910.059
camera type eye developmentGO:00430102660.057
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.055
mrna transportGO:0051028130.054
regulation of protein kinase activityGO:00458592320.053
methylationGO:00322591340.052
heterocycle catabolic processGO:00467002800.052
amine metabolic processGO:0009308450.051
ribose phosphate metabolic processGO:00196932910.051
establishment or maintenance of cytoskeleton polarityGO:003095220.051
organelle fissionGO:00482851700.050
ribose phosphate biosynthetic processGO:0046390590.050
membrane organizationGO:00610242450.048
purine ribonucleoside triphosphate catabolic processGO:00092071990.047
nucleoside phosphate biosynthetic processGO:1901293790.047
negative regulation of phosphate metabolic processGO:00459361840.044
positive regulation of protein modification processGO:00314012990.044
alternative mrna splicing via spliceosomeGO:0000380120.044
hematopoietic progenitor cell differentiationGO:00022441430.044
regionalizationGO:00030023370.043
myeloid cell differentiationGO:00300992330.043
mitotic cell cycle processGO:19030471590.042
response to radiationGO:00093141650.041
organonitrogen compound biosynthetic processGO:19015661920.041
nucleotide metabolic processGO:00091173320.040
regulation of kinase activityGO:00435492490.040
localization within membraneGO:005166840.039
rna catabolic processGO:0006401290.037
covalent chromatin modificationGO:00165691630.036
endocytosisGO:00068971680.036
regulation of protein localizationGO:00328802310.036
regulation of cellular amino acid metabolic processGO:000652150.035
epithelial tube morphogenesisGO:00605623030.034
apoptotic signaling pathwayGO:00971903060.034
rna processingGO:00063961050.034
macromolecule catabolic processGO:00090572810.033
carbohydrate derivative catabolic processGO:19011362310.033
negative regulation of cellular component organizationGO:00511291940.033
negative regulation of protein metabolic processGO:00512482820.033
development of primary sexual characteristicsGO:00451371430.032
cellular amine metabolic processGO:0044106440.032
glycosyl compound catabolic processGO:19016582060.032
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.032
ribonucleoside catabolic processGO:00424542060.032
purine nucleotide catabolic processGO:00061952110.032
organic cyclic compound catabolic processGO:19013612950.031
response to organic cyclic compoundGO:00140701980.031
rna splicing via transesterification reactionsGO:0000375430.030
phagocytosisGO:0006909660.030
negative regulation of phosphorus metabolic processGO:00105631840.030
ribonucleoside triphosphate catabolic processGO:00092031990.029
regulation of cellular amine metabolic processGO:0033238200.029
negative regulation of cellular protein metabolic processGO:00322692470.029
purine nucleoside triphosphate catabolic processGO:00091462030.029
wnt signaling pathwayGO:00160551880.028
negative regulation of protein modification processGO:00314001630.028
establishment of rna localizationGO:0051236180.028
nucleoside catabolic processGO:00091642060.028
regulation of organelle organizationGO:00330432890.028
sensory organ morphogenesisGO:00905962420.028
positive regulation of apoptotic processGO:00430652170.028
ribonucleotide catabolic processGO:00092612080.028
nuclear divisionGO:00002801580.027
ras protein signal transductionGO:0007265770.027
mitotic cell cycleGO:00002781950.027
negative regulation of cell proliferationGO:00082852960.027
translationGO:0006412930.027
cardiac muscle contractionGO:0060048320.026
retina development in camera type eyeGO:00600411190.026
alpha amino acid metabolic processGO:1901605590.026
oxidation reduction processGO:00551143420.026
canonical wnt signaling pathwayGO:00600701300.025
blood circulationGO:00080151950.025
regulation of purine nucleotide metabolic processGO:19005421690.025
histone modificationGO:00165701590.025
ribonucleotide biosynthetic processGO:0009260590.025
nucleoside phosphate catabolic processGO:19012922220.025
negative regulation of phosphorylationGO:00423261660.025
epithelial cell proliferationGO:00506731740.025
purine ribonucleoside catabolic processGO:00461302050.024
negative regulation of intracellular signal transductionGO:19025321670.024
actin cytoskeleton organizationGO:00300362200.024
regulation of nucleotide catabolic processGO:00308111220.024
small gtpase mediated signal transductionGO:0007264970.024
neural precursor cell proliferationGO:00613511210.024
rna splicingGO:0008380540.023
regulation of cell cycleGO:00517262810.023
nucleic acid transportGO:0050657180.023
regulation of intracellular protein transportGO:0033157820.023
spermatogenesisGO:00072832840.023
purine ribonucleoside metabolic processGO:00461282410.023
regulation of mapk cascadeGO:00434082480.023
myeloid leukocyte differentiationGO:00025731190.023
demethylationGO:0070988230.023
regulation of epithelial cell proliferationGO:00506781410.023
organophosphate catabolic processGO:00464342320.023
nucleus organizationGO:0006997450.023
respiratory system developmentGO:00605411900.022
ribonucleoside triphosphate metabolic processGO:00091992200.022
regulation of purine nucleotide catabolic processGO:00331211220.022
regulation of apoptotic signaling pathwayGO:20012331970.021
protein alkylationGO:0008213810.021
purine containing compound metabolic processGO:00725213110.021
organonitrogen compound catabolic processGO:19015652640.021
regulation of cellular component biogenesisGO:00440871810.021
positive regulation of protein kinase activityGO:00458601440.021
regulation of mrna stabilityGO:0043488230.021
purine nucleoside metabolic processGO:00422782410.021
intracellular protein transportGO:00068862040.021
purine nucleoside catabolic processGO:00061522050.021
purine containing compound catabolic processGO:00725232130.021
t cell activationGO:00421102890.021
multicellular organismal signalingGO:0035637910.020
neuronal action potentialGO:0019228540.020
regulation of cellular catabolic processGO:00313292420.020
cellular biogenic amine metabolic processGO:0006576280.020
positive regulation of rna splicingGO:0033120120.020
regulation of wnt signaling pathwayGO:00301111230.020
regulation of cell migrationGO:00303342190.020
regulation of mrna metabolic processGO:1903311430.020
homeostasis of number of cellsGO:00488722100.020
cellular response to lipidGO:00713961450.020
protein targetingGO:00066051430.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
heart contractionGO:0060047930.019
mesenchymal cell differentiationGO:00487621070.019
rna transportGO:0050658180.019
myosin filament organizationGO:003103330.019
rna localizationGO:0006403230.019
regulation of mrna processingGO:0050684410.019
epithelium migrationGO:0090132630.019
oocyte constructionGO:000730820.019
circulatory system processGO:00030131970.019
cellular response to dna damage stimulusGO:00069742070.019
male gamete generationGO:00482322850.019
regulation of nucleocytoplasmic transportGO:0046822730.018
mapk cascadeGO:00001652810.018
leukocyte differentiationGO:00025213420.018
t cell proliferationGO:00420981200.018
dephosphorylationGO:00163111290.018
b cell activationGO:00421131610.018
leukocyte proliferationGO:00706611720.018
multi multicellular organism processGO:00447061090.018
multicellular organismal homeostasisGO:00488711640.018
cell maturationGO:00484691270.018
histone h3 k36 demethylationGO:007054420.018
maternal determination of anterior posterior axis embryoGO:000835820.017
mesenchyme developmentGO:00604851520.017
sequestering of calcium ionGO:0051208180.017
lymphocyte proliferationGO:00466511640.017
mesenchymal cell developmentGO:0014031930.017
oocyte anterior posterior axis specificationGO:000731420.017
peptidyl amino acid modificationGO:00181933360.017
cell adhesionGO:00071553290.017
regulation of gtp catabolic processGO:00331241130.017
stem cell differentiationGO:00488632680.017
transmembrane transportGO:00550854120.017
gene silencingGO:0016458380.017
regulation of protein serine threonine kinase activityGO:00719001570.017
regulation of cell projection organizationGO:00313442060.017
regulation of nucleotide metabolic processGO:00061401690.017
protein modification by small protein conjugationGO:00324461870.017
gtp metabolic processGO:00460391440.017
regulation of intracellular transportGO:00323861590.017
intrinsic apoptotic signaling pathwayGO:00971931320.017
inflammatory responseGO:00069542440.016
locomotory behaviorGO:00076261950.016
regulation of transferase activityGO:00513382630.016
cellular protein complex assemblyGO:00436231160.016
gonad developmentGO:00084061410.016
ossificationGO:00015032160.016
nuclear exportGO:0051168340.016
peptidyl lysine modificationGO:0018205770.016
lipid biosynthetic processGO:00086101790.016
negative regulation of apoptotic signaling pathwayGO:20012341040.016
engulfment of apoptotic cellGO:004365230.016
cellular ketone metabolic processGO:0042180840.016
mrna export from nucleusGO:0006406110.016
positive regulation of cell deathGO:00109422240.016
regulation of chromatin modificationGO:1903308570.016
transmission of nerve impulseGO:0019226760.016
response to acid chemicalGO:00011011110.015
skeletal system morphogenesisGO:00487052030.015
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.015
rhythmic processGO:00485111740.015
regulation of hydrolase activityGO:00513362460.015
positive regulation of mrna processingGO:0050685160.015
regulation of synaptic growth at neuromuscular junctionGO:000858240.015
small molecule biosynthetic processGO:00442831320.015
muscle contractionGO:00069361010.015
stem cell developmentGO:00488642190.015
response to light stimulusGO:00094161350.015
positive regulation of kinase activityGO:00336741550.015
negative regulation of cell activationGO:00508661110.015
neuron deathGO:00709971540.015
response to extracellular stimulusGO:00099911270.015
response to lipopolysaccharideGO:00324961280.015
regulation of hormone levelsGO:00108172110.015
positive regulation of programmed cell deathGO:00430682180.015
ubiquitin dependent protein catabolic processGO:00065111290.014
meiotic cell cycleGO:00513211220.014
spermatid differentiationGO:00485151150.014
branching morphogenesis of an epithelial tubeGO:00487541590.014
regulation of cellular ketone metabolic processGO:0010565660.014
purine ribonucleotide metabolic processGO:00091502900.014
nucleocytoplasmic transportGO:00069131390.014
genitalia developmentGO:0048806370.014
ribosomal small subunit biogenesisGO:004227440.014
cellular homeostasisGO:00197252400.014
positive regulation of protein serine threonine kinase activityGO:00719021060.014
vesicle organizationGO:0016050600.014
pole plasm assemblyGO:000731520.014
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.014
connective tissue developmentGO:00614481790.014
compound eye developmentGO:004874910.014
receptor mediated endocytosisGO:0006898510.014
lipoprotein metabolic processGO:0042157430.014
negative regulation of cellular amine metabolic processGO:003323910.014
regulation of cell morphogenesis involved in differentiationGO:00107691510.014
action potentialGO:0001508780.014
placenta developmentGO:00018901400.014
lipid transportGO:0006869980.014
regulation of protein bindingGO:0043393600.014
heart processGO:0003015940.014
regulation of rna stabilityGO:0043487260.013
epithelial to mesenchymal transitionGO:0001837470.013
neuron projection guidanceGO:00974851410.013
nucleoside triphosphate catabolic processGO:00091432050.013
negative regulation of mrna processingGO:0050686120.013
response to nutrient levelsGO:00316671090.013
regulation of cell motilityGO:20001452360.013
cell type specific apoptotic processGO:00972852680.013
regulation of canonical wnt signaling pathwayGO:0060828820.013
positive regulation of protein phosphorylationGO:00019342420.013
microtubule based processGO:00070172360.013
glycerolipid biosynthetic processGO:0045017500.013
response to organonitrogen compoundGO:00102432460.013
i kappab kinase nf kappab signalingGO:0007249850.013
stem cell proliferationGO:00720891170.013
sensory perceptionGO:00076002450.013
sulfur compound metabolic processGO:00067901000.013
regulation of vesicle mediated transportGO:00606271390.013
regulation of cell activationGO:00508652890.013
protein import into nucleusGO:0006606950.013
morphogenesis of a branching epitheliumGO:00611381930.013
cellular response to organonitrogen compoundGO:00714171450.012
photoreceptor cell differentiationGO:0046530520.012
circadian rhythmGO:00076231140.012
muscle system processGO:00030121410.012
tissue homeostasisGO:00018941150.012
cation transportGO:00068123990.012
divalent metal ion transportGO:00708381720.012
blood vessel morphogenesisGO:00485142850.012
ion transmembrane transportGO:00342203610.012
respiratory tube developmentGO:00303231670.012
multicellular organism growthGO:00352641610.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
macromolecule methylationGO:00434141200.012
digestive system developmentGO:00551232000.012
regulation of secretionGO:00510462740.012
maintenance of locationGO:0051235890.012
negative regulation of synapse assemblyGO:005196430.012
dna modificationGO:0006304500.012
myosin filament assemblyGO:003103420.012
positive regulation of chromosome segregationGO:005198440.012
coenzyme metabolic processGO:0006732520.012
protein importGO:00170381010.012
cellular lipid metabolic processGO:00442553230.012
purine ribonucleotide catabolic processGO:00091542080.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
developmental growth involved in morphogenesisGO:00605601380.012
regulation of mrna splicing via spliceosomeGO:0048024320.012
cellular response to acid chemicalGO:0071229680.012
inter male aggressive behaviorGO:000212130.012
regulation of myeloid cell differentiationGO:0045637960.011
regulation of chromosome organizationGO:0033044830.011
regulation of neuron projection developmentGO:00109751690.011
muscle tissue morphogenesisGO:0060415530.011
glucose homeostasisGO:00425931280.011
regulation of bindingGO:00510981110.011
mature dendritic cell differentiationGO:009702930.011
regulation of cellular response to stressGO:00801351590.011
circadian regulation of gene expressionGO:0032922480.011
cellular protein catabolic processGO:00442571550.011
negative regulation of nucleotide metabolic processGO:0045980160.011
pharynx developmentGO:006046510.011
positive regulation of cellular amino acid metabolic processGO:004576430.011
response to amino acidGO:0043200370.011
negative regulation of wnt signaling pathwayGO:0030178730.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.011
lung developmentGO:00303241640.011
intracellular mrna localizationGO:000829840.011
regulation of protein complex assemblyGO:0043254830.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.011
cellular chemical homeostasisGO:00550822150.011
negative regulation of rna splicingGO:0033119120.011
cartilage developmentGO:00512161400.011
heart morphogenesisGO:00030071780.011
nuclear importGO:0051170950.011
response to molecule of bacterial originGO:00022371430.011
response to inorganic substanceGO:0010035960.011
nuclear transcribed mrna catabolic processGO:0000956160.011
positive regulation of dna templated transcription elongationGO:003278620.011
nuclear transportGO:00511691390.011
gliogenesisGO:00420631410.011
divalent inorganic cation transportGO:00725111780.011
histone acetylationGO:0016573410.010
positive regulation of cellular component biogenesisGO:0044089940.010
regulation of organ morphogenesisGO:20000271440.010
protein acylationGO:0043543640.010
establishment or maintenance of cell polarityGO:0007163860.010
protein modification by small protein conjugation or removalGO:00706472070.010
cellular modified amino acid metabolic processGO:0006575630.010
calcium ion transportGO:00068161590.010
regulation of inflammatory responseGO:00507271470.010
cell fate commitmentGO:00451652100.010
mitotic nuclear divisionGO:0007067480.010
atp catabolic processGO:0006200550.010
carbohydrate derivative biosynthetic processGO:19011371830.010

Tdg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.031
nervous system diseaseDOID:86300.031
central nervous system diseaseDOID:33100.030
neurodegenerative diseaseDOID:128900.025
cancerDOID:16200.017
disease of cellular proliferationDOID:1456600.017
colon cancerDOID:21900.016
large intestine cancerDOID:567200.016
gastrointestinal system cancerDOID:311900.016
organ system cancerDOID:005068600.016
intestinal cancerDOID:1015500.016
colorectal cancerDOID:925600.016
neuropathyDOID:87000.013