IMP: Integrative Multi-species Prediction

Mus musculus

187 known processes

Rasgrp1

RAS guanyl releasing protein 1

(Aliases: Rasgrp)

Entrez: 19419
Ensembl: ENSMUSG00000027347
UniProtKB: Q9Z1S3

Process Predictions
Disease Predictions

Rasgrp1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
synaptic transmission	GO:0007268	329	0.890
gtp metabolic process	GO:0046039	144	0.874
nucleotide catabolic process	GO:0009166	217	0.729
ras protein signal transduction	GO:0007265	77	0.704	Mouse
gtp catabolic process	GO:0006184	143	0.684
small gtpase mediated signal transduction	GO:0007264	97	0.667	Mouse
regulation of gtp catabolic process	GO:0033124	113	0.631
cation transport	GO:0006812	399	0.618
immune response regulating cell surface receptor signaling pathway	GO:0002768	80	0.576
nucleoside catabolic process	GO:0009164	206	0.547
organophosphate catabolic process	GO:0046434	232	0.529
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.528
purine ribonucleotide catabolic process	GO:0009154	208	0.524
regulation of cell activation	GO:0050865	289	0.510
cellular amino acid metabolic process	GO:0006520	103	0.507
glycosyl compound catabolic process	GO:1901658	206	0.505
divalent metal ion transport	GO:0070838	172	0.492
guanosine containing compound catabolic process	GO:1901069	144	0.485
immune response activating cell surface receptor signaling pathway	GO:0002429	72	0.471
actin cytoskeleton organization	GO:0030036	220	0.467
positive regulation of ras gtpase activity	GO:0032320	65	0.459
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.446
nucleoside phosphate catabolic process	GO:1901292	222	0.439
ribonucleoside metabolic process	GO:0009119	245	0.432
peptidyl amino acid modification	GO:0018193	336	0.428
regulation of ras gtpase activity	GO:0032318	88	0.421
positive regulation of gtp catabolic process	GO:0033126	85	0.417
cognition	GO:0050890	149	0.409
positive regulation of gtpase activity	GO:0043547	85	0.405
organic cyclic compound catabolic process	GO:1901361	295	0.404
purine containing compound metabolic process	GO:0072521	311	0.397
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.396
heterocycle catabolic process	GO:0046700	280	0.391
regulation of cell migration	GO:0030334	219	0.390
organonitrogen compound catabolic process	GO:1901565	264	0.390
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.376
cellular lipid metabolic process	GO:0044255	323	0.372
positive regulation of cellular amine metabolic process	GO:0033240	5	0.369
purine nucleotide catabolic process	GO:0006195	211	0.363
rho protein signal transduction	GO:0007266	32	0.354
ribonucleotide catabolic process	GO:0009261	208	0.350
regulation of cytoskeleton organization	GO:0051493	122	0.347
purine ribonucleoside metabolic process	GO:0046128	241	0.340
learning or memory	GO:0007611	148	0.338
regulation of protein kinase activity	GO:0045859	232	0.332
purine containing compound catabolic process	GO:0072523	213	0.331
nucleoside triphosphate metabolic process	GO:0009141	230	0.330
maintenance of location	GO:0051235	89	0.330
purine nucleoside catabolic process	GO:0006152	205	0.321
microtubule based process	GO:0007017	236	0.314
protein polymerization	GO:0051258	57	0.313
regulation of purine nucleotide metabolic process	GO:1900542	169	0.311
nucleoside triphosphate catabolic process	GO:0009143	205	0.311
regulation of rho gtpase activity	GO:0032319	58	0.301
nucleobase containing small molecule metabolic process	GO:0055086	352	0.296
g protein coupled receptor internalization	GO:0002031	3	0.295
cellular nitrogen compound catabolic process	GO:0044270	280	0.292
glial cell differentiation	GO:0010001	131	0.287
cellular response to growth factor stimulus	GO:0071363	197	0.286
guanosine containing compound metabolic process	GO:1901068	144	0.283
ribose phosphate metabolic process	GO:0019693	291	0.283
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.278
asymmetric neuroblast division	GO:0055059	1	0.274
lymphocyte proliferation	GO:0046651	164	0.271
amine metabolic process	GO:0009308	45	0.269
cellular ketone metabolic process	GO:0042180	84	0.268
purine ribonucleoside catabolic process	GO:0046130	205	0.268
nucleotide metabolic process	GO:0009117	332	0.267
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.265
sequestering of metal ion	GO:0051238	19	0.263
t cell differentiation	GO:0030217	174	0.261
mapk cascade	GO:0000165	281	0.258
neuronal action potential	GO:0019228	54	0.258
regulation of cellular amino acid metabolic process	GO:0006521	5	0.257
multicellular organismal signaling	GO:0035637	91	0.254
cation homeostasis	GO:0055080	212	0.253
sequestering of calcium ion	GO:0051208	18	0.252
transmission of nerve impulse	GO:0019226	76	0.246
positive regulation of cellular catabolic process	GO:0031331	148	0.246
cytoplasmic transport	GO:0016482	234	0.246
ribonucleotide metabolic process	GO:0009259	291	0.245
vesicle localization	GO:0051648	86	0.242
aromatic compound catabolic process	GO:0019439	286	0.234
intracellular protein transport	GO:0006886	204	0.232
cellular amine metabolic process	GO:0044106	44	0.231
regulation of kinase activity	GO:0043549	249	0.221
regulation of purine nucleotide catabolic process	GO:0033121	122	0.220
response to growth factor	GO:0070848	198	0.217
regulation of membrane potential	GO:0042391	192	0.205
regulation of hydrolase activity	GO:0051336	246	0.205
inorganic cation transmembrane transport	GO:0098662	207	0.203
nuclear transport	GO:0051169	139	0.203
cellular homeostasis	GO:0019725	240	0.200
regulation of t cell activation	GO:0050863	170	0.199
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.196
regulation of nucleotide catabolic process	GO:0030811	122	0.195
nucleoside metabolic process	GO:0009116	246	0.195
regulation of organelle organization	GO:0033043	289	0.195
protein localization to membrane	GO:0072657	108	0.195
actin polymerization or depolymerization	GO:0008154	54	0.191
negative regulation of phosphate metabolic process	GO:0045936	184	0.189
regulation of transferase activity	GO:0051338	263	0.189
regulation of nucleoside metabolic process	GO:0009118	130	0.189
single organism cell adhesion	GO:0098602	156	0.188
actin filament polymerization	GO:0030041	44	0.188
long term synaptic potentiation	GO:0060291	25	0.185
glial cell development	GO:0021782	54	0.185
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation	GO:2000721	2	0.185
purine nucleoside metabolic process	GO:0042278	241	0.182
axonogenesis	GO:0007409	274	0.181
establishment of vesicle localization	GO:0051650	81	0.180
cellular calcium ion homeostasis	GO:0006874	119	0.179
positive regulation of hydrolase activity	GO:0051345	148	0.177
glycosyl compound metabolic process	GO:1901657	246	0.173
leukocyte mediated immunity	GO:0002443	174	0.171
memory	GO:0007613	58	0.170
carbohydrate derivative catabolic process	GO:1901136	231	0.170
positive regulation of nucleotide metabolic process	GO:0045981	114	0.170
second messenger mediated signaling	GO:0019932	73	0.170
purine nucleotide metabolic process	GO:0006163	302	0.168
embryonic genitalia morphogenesis	GO:0030538	4	0.168
brown fat cell differentiation	GO:0050873	36	0.168
positive regulation of nucleoside metabolic process	GO:0045979	91	0.166
positive regulation of nucleotide catabolic process	GO:0030813	88	0.165
canonical wnt signaling pathway	GO:0060070	130	0.165
gliogenesis	GO:0042063	141	0.164
extrinsic apoptotic signaling pathway	GO:0097191	126	0.164
angiogenesis	GO:0001525	201	0.164
regulation of lymphocyte activation	GO:0051249	240	0.160
membrane organization	GO:0061024	245	0.159
developmental cell growth	GO:0048588	84	0.157
single organismal cell cell adhesion	GO:0016337	131	0.156
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.154
leukocyte differentiation	GO:0002521	342	0.153
leukocyte proliferation	GO:0070661	172	0.149
urogenital system development	GO:0001655	261	0.149
regulation of anatomical structure size	GO:0090066	178	0.148
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.147
regulation of antigen receptor mediated signaling pathway	GO:0050854	29	0.145
regulation of nucleotide metabolic process	GO:0006140	169	0.144
visual behavior	GO:0007632	45	0.143
divalent inorganic cation homeostasis	GO:0072507	138	0.143
purine ribonucleotide metabolic process	GO:0009150	290	0.142
cellular chemical homeostasis	GO:0055082	215	0.142
negative regulation of phosphorylation	GO:0042326	166	0.141
phospholipid metabolic process	GO:0006644	87	0.139
antigen receptor mediated signaling pathway	GO:0050851	64	0.139
regulation of cell projection organization	GO:0031344	206	0.139
cell chemotaxis	GO:0060326	81	0.138
g protein coupled receptor signaling pathway	GO:0007186	243	0.134
positive regulation of kinase activity	GO:0033674	155	0.133
action potential	GO:0001508	78	0.132
ion transmembrane transport	GO:0034220	361	0.131
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.131
calcium ion transport	GO:0006816	159	0.131
regulation of cell motility	GO:2000145	236	0.131
immune effector process	GO:0002252	321	0.130
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.129
positive regulation of vesicle fusion	GO:0031340	2	0.129
amino acid transport	GO:0006865	61	0.129
cell adhesion	GO:0007155	329	0.129
negative regulation of protein phosphorylation	GO:0001933	126	0.128
organelle localization	GO:0051640	179	0.128
muscle tissue development	GO:0060537	308	0.128
regulation of vesicle mediated transport	GO:0060627	139	0.128
asymmetric stem cell division	GO:0098722	3	0.126
plasma membrane organization	GO:0007009	90	0.126
learning	GO:0007612	98	0.126
positive regulation of protein targeting to membrane	GO:0090314	7	0.124
regulation of ion transport	GO:0043269	215	0.123
positive regulation of cell activation	GO:0050867	158	0.121
negative regulation of cellular component organization	GO:0051129	194	0.120
organic acid transport	GO:0015849	101	0.119
synaptic transmission gabaergic	GO:0051932	19	0.118
germ cell development	GO:0007281	185	0.118
regulation of actin polymerization or depolymerization	GO:0008064	45	0.117
positive regulation of lymphocyte activation	GO:0051251	140	0.117
regulation of response to drug	GO:2001023	2	0.116
erk1 and erk2 cascade	GO:0070371	77	0.116
regulation of actin filament length	GO:0030832	45	0.115
lymphocyte differentiation	GO:0030098	242	0.115
regulation of leukocyte differentiation	GO:1902105	159	0.115
regulation of cellular ketone metabolic process	GO:0010565	66	0.115
positive regulation of protein modification process	GO:0031401	299	0.115
microglia differentiation	GO:0014004	2	0.114
positive regulation of cell development	GO:0010720	237	0.114
nucleoside phosphate metabolic process	GO:0006753	338	0.114
operant conditioning	GO:0035106	2	0.114
exocytosis	GO:0006887	121	0.114
negative regulation of synapse assembly	GO:0051964	3	0.113
positive regulation of organelle organization	GO:0010638	128	0.113
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.112
regulation of protein serine threonine kinase activity	GO:0071900	157	0.112
regulation of homeostatic process	GO:0032844	182	0.112
regulation of ras protein signal transduction	GO:0046578	114	0.111
negative regulation of protein metabolic process	GO:0051248	282	0.110
sensitization	GO:0046960	2	0.109
homeostasis of number of cells	GO:0048872	210	0.109
synaptic vesicle localization	GO:0097479	59	0.108
endocytosis	GO:0006897	168	0.108
negative regulation of phosphorus metabolic process	GO:0010563	184	0.107
regulation of actin cytoskeleton organization	GO:0032956	84	0.107
telencephalon cell migration	GO:0022029	55	0.106
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.106
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.106
positive regulation of defense response	GO:0031349	124	0.105
renal system development	GO:0072001	225	0.105
membrane tubulation	GO:0097320	4	0.105
regulation of cellular component size	GO:0032535	121	0.104
microtubule cytoskeleton organization	GO:0000226	157	0.104
natural killer cell activation	GO:0030101	44	0.103
actin filament organization	GO:0007015	113	0.102
negative regulation of lymphocyte activation	GO:0051250	91	0.102
adult behavior	GO:0030534	135	0.101
positive regulation of mapk cascade	GO:0043410	170	0.100
cellular ion homeostasis	GO:0006873	165	0.100
regulation of protein localization	GO:0032880	231	0.099
regulation of secretion	GO:0051046	274	0.099
divalent inorganic cation transport	GO:0072511	178	0.098
wnt signaling pathway	GO:0016055	188	0.097
regulation of natural killer cell activation	GO:0032814	22	0.097
activation of immune response	GO:0002253	138	0.097
cell division	GO:0051301	120	0.097
cytokine production	GO:0001816	319	0.096
t cell activation	GO:0042110	289	0.095
positive regulation of rac gtpase activity	GO:0032855	14	0.095
negative regulation of cellular protein metabolic process	GO:0032269	247	0.094
positive regulation of transferase activity	GO:0051347	167	0.093
negative regulation of map kinase activity	GO:0043407	34	0.093
microglia development	GO:0014005	2	0.092
forebrain development	GO:0030900	302	0.092
protein targeting	GO:0006605	143	0.091
monocarboxylic acid metabolic process	GO:0032787	191	0.090
protein kinase c activating g protein coupled receptor signaling pathway	GO:0007205	4	0.090
response to organic cyclic compound	GO:0014070	198	0.089
regulation of high voltage gated calcium channel activity	GO:1901841	2	0.087
neuron projection extension	GO:1990138	64	0.087
positive regulation of protein phosphorylation	GO:0001934	242	0.087
amide transport	GO:0042886	138	0.087
regulation of voltage gated calcium channel activity	GO:1901385	4	0.086
monosaccharide transport	GO:0015749	58	0.086
negative regulation of protein modification process	GO:0031400	163	0.086
apoptotic signaling pathway	GO:0097190	306	0.085
regulation of map kinase activity	GO:0043405	120	0.085
sensory perception	GO:0007600	245	0.084
forebrain cell migration	GO:0021885	58	0.084
positive regulation of heart rate by epinephrine norepinephrine	GO:0001996	4	0.084
filopodium assembly	GO:0046847	19	0.084
sodium ion transport	GO:0006814	73	0.083
neuron neuron synaptic transmission	GO:0007270	69	0.083
microtubule based movement	GO:0007018	84	0.083
negative regulation of intracellular signal transduction	GO:1902532	167	0.083
positive regulation of cell migration	GO:0030335	109	0.082
regulation of cellular amine metabolic process	GO:0033238	20	0.081
regulation of metal ion transport	GO:0010959	106	0.080
anatomical structure arrangement	GO:0048532	20	0.080
positive regulation of cell motility	GO:2000147	116	0.080
regulation of endocytosis	GO:0030100	69	0.079
anion transport	GO:0006820	177	0.079
metal ion homeostasis	GO:0055065	189	0.079
negative regulation of homeostatic process	GO:0032845	71	0.077
protein localization to organelle	GO:0033365	185	0.077
positive regulation of secretion	GO:0051047	130	0.077
adult locomotory behavior	GO:0008344	91	0.077
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.077
synaptic vesicle transport	GO:0048489	57	0.077
positive regulation of t cell activation	GO:0050870	101	0.076
positive regulation of protein kinase activity	GO:0045860	144	0.076
gland development	GO:0048732	330	0.075
inflammatory response	GO:0006954	244	0.075
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.074
cellular response to organonitrogen compound	GO:0071417	145	0.074
regulation of t cell differentiation	GO:0045580	83	0.074
oocyte axis specification	GO:0007309	2	0.074
immune response regulating signaling pathway	GO:0002764	125	0.073
regulation of mapk cascade	GO:0043408	248	0.073
axon guidance	GO:0007411	141	0.073
regulation of establishment of protein localization	GO:0070201	181	0.072
positive regulation of cytoskeleton organization	GO:0051495	49	0.072
extrinsic apoptotic signaling pathway in absence of ligand	GO:0097192	55	0.072
regulation of cytokine production	GO:0001817	266	0.072
granulocyte migration	GO:0097530	43	0.072
regulation of peptide transport	GO:0090087	91	0.072
peptidyl tyrosine modification	GO:0018212	145	0.071
protein localization to nucleus	GO:0034504	121	0.071
generation of precursor metabolites and energy	GO:0006091	103	0.071
cellular protein complex assembly	GO:0043623	116	0.071
positive regulation of t cell proliferation	GO:0042102	52	0.070
peptidyl tyrosine phosphorylation	GO:0018108	143	0.070
ribonucleoside catabolic process	GO:0042454	206	0.070
i kappab kinase nf kappab signaling	GO:0007249	85	0.070
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway	GO:0051482	4	0.070
associative learning	GO:0008306	61	0.069
negative regulation of cell motility	GO:2000146	61	0.068
glucose transport	GO:0015758	56	0.068
establishment of organelle localization	GO:0051656	122	0.068
regulation of extent of cell growth	GO:0061387	52	0.068
regulation of exocytosis	GO:0017157	61	0.068
myeloid cell differentiation	GO:0030099	233	0.068
regulation of angiogenesis	GO:0045765	81	0.068
lipid biosynthetic process	GO:0008610	179	0.068
nucleocytoplasmic transport	GO:0006913	139	0.067
regulation of cellular catabolic process	GO:0031329	242	0.067
positive regulation of rho gtpase activity	GO:0032321	41	0.067
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.066
regulation of leukocyte proliferation	GO:0070663	121	0.066
negative regulation of mapk cascade	GO:0043409	65	0.066
positive regulation of interleukin 5 secretion	GO:2000664	1	0.066
regulation of erk1 and erk2 cascade	GO:0070372	71	0.065
glucose homeostasis	GO:0042593	128	0.065
positive regulation of cellular component biogenesis	GO:0044089	94	0.063
sensory perception of pain	GO:0019233	47	0.063
regulation of synaptic plasticity	GO:0048167	87	0.063
regulation of the force of heart contraction	GO:0002026	17	0.063
cell growth	GO:0016049	130	0.063
nitrogen compound transport	GO:0071705	271	0.063
regulation of actin filament polymerization	GO:0030833	38	0.063
positive regulation of intracellular transport	GO:0032388	70	0.062
calcium mediated signaling	GO:0019722	46	0.062
cellular metal ion homeostasis	GO:0006875	151	0.062
regulation of lipid metabolic process	GO:0019216	118	0.062
kidney development	GO:0001822	213	0.061
regulation of actin filament based process	GO:0032970	99	0.061
vesicle organization	GO:0016050	60	0.061
photoreceptor cell differentiation	GO:0046530	52	0.061
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	43	0.061
regulation of intracellular transport	GO:0032386	159	0.060
signal transduction in absence of ligand	GO:0038034	55	0.060
response to radiation	GO:0009314	165	0.060
calcium ion homeostasis	GO:0055074	127	0.060
response to organonitrogen compound	GO:0010243	246	0.060
tissue remodeling	GO:0048771	102	0.060
organic acid biosynthetic process	GO:0016053	86	0.059
regulation of neuron projection development	GO:0010975	169	0.059
calcium ion transport into cytosol	GO:0060402	48	0.059
regulation of cell adhesion	GO:0030155	154	0.058
negative regulation of cell migration	GO:0030336	59	0.058
cellular carbohydrate metabolic process	GO:0044262	119	0.058
granulocyte chemotaxis	GO:0071621	39	0.058
ameboidal type cell migration	GO:0001667	128	0.057
blood vessel morphogenesis	GO:0048514	285	0.057
establishment of neuroblast polarity	GO:0045200	1	0.057
response to ethanol	GO:0045471	18	0.057
positive regulation of secretion by cell	GO:1903532	114	0.057
cytokine mediated signaling pathway	GO:0019221	115	0.057
positive regulation of endothelial cell proliferation	GO:0001938	17	0.056
carbohydrate homeostasis	GO:0033500	128	0.056
carbohydrate metabolic process	GO:0005975	230	0.055
regulation of lymphocyte differentiation	GO:0045619	107	0.055
negative regulation of cellular amine metabolic process	GO:0033239	1	0.054
protein kinase b signaling	GO:0043491	74	0.054
carbohydrate transport	GO:0008643	62	0.054
axon ensheathment	GO:0008366	76	0.054
positive regulation of nervous system development	GO:0051962	221	0.054
positive regulation of the force of heart contraction by epinephrine norepinephrine	GO:0001997	3	0.054
regulation of protein transport	GO:0051223	163	0.054
carboxylic acid biosynthetic process	GO:0046394	86	0.054
regulation of system process	GO:0044057	200	0.054
alpha beta t cell differentiation	GO:0046632	69	0.053
dendritic spine organization	GO:0097061	26	0.053
anatomical structure homeostasis	GO:0060249	145	0.052
inorganic ion transmembrane transport	GO:0098660	234	0.052
endomembrane system organization	GO:0010256	147	0.052
multi multicellular organism process	GO:0044706	109	0.052
myeloid cell activation involved in immune response	GO:0002275	34	0.052
positive regulation of necrotic cell death	GO:0010940	1	0.052
fatty acid metabolic process	GO:0006631	121	0.052
serotonin metabolic process	GO:0042428	8	0.052
dendrite development	GO:0016358	115	0.051
innervation	GO:0060384	22	0.051
positive regulation of lymphocyte differentiation	GO:0045621	61	0.051
protein autophosphorylation	GO:0046777	61	0.051
leukocyte migration	GO:0050900	124	0.051
muscle cell differentiation	GO:0042692	261	0.051
positive regulation of protein transport	GO:0051222	93	0.051
chemotaxis	GO:0006935	247	0.051
cellular response to interleukin 15	GO:0071350	2	0.050
protein import into nucleus	GO:0006606	95	0.050
bone resorption	GO:0045453	38	0.049
fibroblast growth factor receptor signaling pathway	GO:0008543	46	0.049
detection of stimulus	GO:0051606	84	0.049
stress activated protein kinase signaling cascade	GO:0031098	81	0.049
peptide hormone secretion	GO:0030072	109	0.049
protein localization to plasma membrane	GO:0072659	57	0.048
fat cell differentiation	GO:0045444	160	0.048
positive regulation of interleukin 13 secretion	GO:2000667	1	0.047
positive regulation of the force of heart contraction by chemical signal	GO:0003099	3	0.047
cell substrate adhesion	GO:0031589	130	0.047
phosphatidylinositol metabolic process	GO:0046488	45	0.047
leukocyte activation involved in immune response	GO:0002366	126	0.047
synaptic transmission glutamatergic	GO:0035249	36	0.047
regulation of hormone levels	GO:0010817	211	0.047
regulation of cellular component biogenesis	GO:0044087	181	0.046
locomotory behavior	GO:0007626	195	0.046
negative regulation of kinase activity	GO:0033673	81	0.046
regulation of neuron death	GO:1901214	134	0.046
t cell differentiation in thymus	GO:0033077	77	0.046
regulation of cell growth	GO:0001558	91	0.046
negative regulation of immune system process	GO:0002683	209	0.046
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.045
regulation of g protein coupled receptor protein signaling pathway	GO:0008277	37	0.045
organic hydroxy compound transport	GO:0015850	93	0.045
heart process	GO:0003015	94	0.044
eosinophil activation	GO:0043307	1	0.044
negative regulation of transferase activity	GO:0051348	85	0.044
epidermis development	GO:0008544	187	0.044
regulation of cytokine secretion	GO:0050707	61	0.044
positive regulation of glycolytic process	GO:0045821	4	0.044
cellular response to cytokine stimulus	GO:0071345	189	0.044
cellular response to lipid	GO:0071396	145	0.044
transmembrane transport	GO:0055085	412	0.044
regulation of t cell mediated immunity	GO:0002709	34	0.043
peptidyl serine phosphorylation	GO:0018105	74	0.043
regulation of ion homeostasis	GO:2000021	64	0.043
nuclear import	GO:0051170	95	0.043
developmental maturation	GO:0021700	193	0.043
regulation of synaptic transmission glutamatergic	GO:0051966	19	0.043
response to interferon gamma	GO:0034341	34	0.042
cellular response to temperature stimulus	GO:0071502	2	0.042
adrenergic receptor signaling pathway	GO:0071875	13	0.042
establishment or maintenance of neuroblast polarity	GO:0045196	1	0.042
cellular response to fibroblast growth factor stimulus	GO:0044344	47	0.042
insulin secretion	GO:0030073	89	0.042
protein modification by small protein conjugation	GO:0032446	187	0.042
leukocyte chemotaxis	GO:0030595	69	0.041
regionalization	GO:0003002	337	0.041
positive regulation of growth	GO:0045927	104	0.041
mitochondrion organization	GO:0007005	134	0.041
response to temperature stimulus	GO:0009266	55	0.041
response to peptide	GO:1901652	136	0.041
gastrin induced gastric acid secretion	GO:0001698	1	0.041
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	1	0.041
response to peptide hormone	GO:0043434	127	0.041
endothelial cell proliferation	GO:0001935	27	0.040
negative regulation of cell activation	GO:0050866	111	0.040
regulation of canonical wnt signaling pathway	GO:0060828	82	0.040
cellular response to hormone stimulus	GO:0032870	150	0.040
activation of mapk activity	GO:0000187	59	0.040
organelle fission	GO:0048285	170	0.040
neuron migration	GO:0001764	122	0.039
nerve development	GO:0021675	67	0.039
regulation of lymphocyte proliferation	GO:0050670	117	0.039
response to ammonium ion	GO:0060359	21	0.039
regulation of peptide hormone secretion	GO:0090276	75	0.038
detection of abiotic stimulus	GO:0009582	60	0.038
vascular process in circulatory system	GO:0003018	62	0.038
clathrin coat assembly	GO:0048268	2	0.038
defense response to other organism	GO:0098542	197	0.038
regulation of inflammatory response	GO:0050727	147	0.038
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090100	43	0.038
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.038
cerebral cortex development	GO:0021987	86	0.037
positive regulation of wnt signaling pathway	GO:0030177	45	0.037
response to transforming growth factor beta	GO:0071559	88	0.037
organic anion transport	GO:0015711	137	0.037
myeloid leukocyte migration	GO:0097529	57	0.037
sphingosine 1 phosphate signaling pathway	GO:0003376	3	0.037
regulation of intracellular protein transport	GO:0033157	82	0.037
establishment of protein localization to organelle	GO:0072594	118	0.036
dephosphorylation	GO:0016311	129	0.036
phospholipase c activating serotonin receptor signaling pathway	GO:0007208	1	0.036
positive regulation of stress activated mapk cascade	GO:0032874	48	0.036
dendritic spine maintenance	GO:0097062	4	0.036
positive regulation of cytokine secretion	GO:0050715	41	0.036
regulation of protein secretion	GO:0050708	82	0.036
negative regulation of t cell activation	GO:0050868	65	0.036
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.036
establishment of synaptic vesicle localization	GO:0097480	57	0.036
carbohydrate derivative biosynthetic process	GO:1901137	183	0.036
leukocyte homeostasis	GO:0001776	79	0.036
organic hydroxy compound metabolic process	GO:1901615	203	0.036
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.036
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.036
optic nerve structural organization	GO:0021633	2	0.035
insulin receptor signaling pathway	GO:0008286	49	0.035
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure	GO:0002025	3	0.035
regulation of calcium mediated signaling	GO:0050848	19	0.035
sulfur compound metabolic process	GO:0006790	100	0.035
rhodopsin mediated signaling pathway	GO:0016056	4	0.035
positive regulation of protein kinase b signaling	GO:0051897	32	0.035
olfactory learning	GO:0008355	2	0.035
negative regulation of defense response	GO:0031348	77	0.035
cation transmembrane transport	GO:0098655	266	0.035
negative regulation of antigen receptor mediated signaling pathway	GO:0050858	16	0.035
negative regulation of neuron apoptotic process	GO:0043524	92	0.034
positive regulation of lymphocyte proliferation	GO:0050671	70	0.034
negative regulation of cell development	GO:0010721	169	0.034
multicellular organismal homeostasis	GO:0048871	164	0.034
ensheathment of neurons	GO:0007272	76	0.034
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	45	0.034
regulation of cell shape	GO:0008360	39	0.034
myelination	GO:0042552	74	0.034
toxin transport	GO:1901998	38	0.034
cell type specific apoptotic process	GO:0097285	268	0.034

Rasgrp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.288
musculoskeletal system disease	DOID:17	0.288
connective tissue disease	DOID:65	0.115
disease of metabolism	DOID:0014667	0.067
bone disease	DOID:0080001	0.053

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