Mus musculus

266 known processes

Nrxn1

neurexin I

(Aliases: A230068P09Rik,1700062G21Rik,mKIAA0578,9330127H16Rik)

Nrxn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cerebellar granular layer developmentGO:0021681131.000
negative regulation of filopodium assemblyGO:005149021.000
regulation of synaptic vesicle recyclingGO:190342121.000
Fly
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activityGO:2000311111.000
cerebellar granular layer formationGO:002168490.998
regulation of glutamate receptor signaling pathwayGO:1900449160.998
cerebellar granule cell differentiationGO:002170790.998
cell cell adhesionGO:0098609410.995
regulation of grooming behaviorGO:200082140.995
regulation of synaptic vesicle endocytosisGO:190024220.995
Fly
regulation of excitatory postsynaptic membrane potentialGO:0060079410.993
postsynaptic membrane assemblyGO:009710460.990
receptor localization to synapseGO:009712040.990
positive regulation of membrane potentialGO:0045838150.990
protein localization to synapseGO:0035418110.989
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:0007157200.988
positive regulation of synaptic vesicle endocytosisGO:190024410.983
Fly
cell differentiation in hindbrainGO:0021533240.980
isoprenoid transportGO:004686430.980
Fly
cerebellum morphogenesisGO:0021587420.975
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742400.970
postsynaptic density protein 95 clusteringGO:009711960.968
regulation of n methyl d aspartate selective glutamate receptor activityGO:2000310100.961
cerebellar cortex formationGO:0021697220.960
n methyl d aspartate receptor clusteringGO:009711430.957
positive regulation of synaptic vesicle transportGO:190280510.955
Fly
hindbrain morphogenesisGO:0021575460.946
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633990.946
regulation of terminal button organizationGO:200033110.934
Fly
neurotransmitter gated ion channel clusteringGO:007257860.929
regulation of postsynaptic membrane potentialGO:0060078480.929
ion transmembrane transportGO:00342203610.925
presynaptic membrane organizationGO:009709080.924
positive regulation of synapse assemblyGO:0051965180.922
auditory behaviorGO:003122330.918
Human
gephyrin clusteringGO:009711630.918
social behaviorGO:0035176210.917
Human
membrane depolarizationGO:0051899640.912
vitamin transportGO:0051180100.893
Fly
central nervous system neuron differentiationGO:00219531620.893
positive regulation of excitatory postsynaptic membrane potentialGO:2000463140.881
neuromuscular process controlling balanceGO:0050885590.873
regulation of synaptic vesicle transportGO:1902803130.869
Fly
terminal button organizationGO:007255330.868
Fly
positive regulation of synaptic vesicle recyclingGO:190342310.864
Fly
synaptic growth at neuromuscular junctionGO:005112460.860
Fly
cerebellar cortex developmentGO:0021695480.853
intraspecies interaction between organismsGO:0051703210.835
Human
glutamate receptor signaling pathwayGO:0007215350.811
regulation of transmembrane transportGO:00347621280.810
establishment of vesicle localizationGO:0051650810.807
Fly
synaptic vesicle transportGO:0048489570.800
Fly
regulation of ion transmembrane transportGO:00347651190.778
positive regulation of establishment of protein localization to plasma membraneGO:009000470.773
regulation of receptor activityGO:0010469410.768
cellular response to carbohydrate stimulusGO:0071322500.757
neuron cell cell adhesionGO:000715860.755
cerebellum developmentGO:0021549770.750
membrane biogenesisGO:0044091120.730
neuromuscular synaptic transmissionGO:0007274160.728
Fly
synapse maturationGO:0060074140.727
cerebellar cortex morphogenesisGO:0021696320.726
presynaptic membrane assemblyGO:009710570.717
neuromuscular processGO:0050905990.709
prepulse inhibitionGO:0060134100.688
glucose homeostasisGO:00425931280.668
establishment of synaptic vesicle localizationGO:0097480570.668
Fly
regulation of ion transmembrane transporter activityGO:0032412540.664
synaptic vesicle clusteringGO:009709130.636
regulation of cell projection organizationGO:00313442060.636
cerebellar granular layer morphogenesisGO:0021683100.634
associative learningGO:0008306610.633
Fly
establishment of protein localization to membraneGO:0090150540.627
lipid transportGO:0006869980.622
Fly
synaptic transmissionGO:00072683290.616
regulation of secretion by cellGO:19035302490.615
hindbrain developmentGO:00309021280.613
regulation of synapse maturationGO:009012890.595
postsynaptic membrane organizationGO:0001941180.577
synaptic vesicle localizationGO:0097479590.570
peptide transportGO:00158331330.566
regulation of neurotransmitter levelsGO:0001505870.560
grooming behaviorGO:0007625160.555
insulin secretion involved in cellular response to glucose stimulusGO:0035773360.555
transmembrane transportGO:00550854120.551
regulation of synapse assemblyGO:0051963290.550
positive regulation of synaptic transmission glutamatergicGO:005196880.546
regulation of insulin secretion involved in cellular response to glucose stimulusGO:0061178310.542
organelle localizationGO:00516401790.537
membrane organizationGO:00610242450.529
synaptic vesicle recyclingGO:0036465190.524
Fly
membrane assemblyGO:0071709120.515
regulation of peptide transportGO:0090087910.511
vesicle localizationGO:0051648860.508
cell adhesionGO:00071553290.508
amide transportGO:00428861380.501
cellular response to monosaccharide stimulusGO:0071326470.497
synaptic transmission glutamatergicGO:0035249360.497
regulation of cell projection assemblyGO:0060491380.487
insulin secretionGO:0030073890.484
regulation of peptide secretionGO:0002791770.482
metencephalon developmentGO:0022037890.478
lipid localizationGO:00108761260.478
Fly
regulation of homeostatic processGO:00328441820.460
positive regulation of protein localization to plasma membraneGO:190307870.459
carbohydrate homeostasisGO:00335001280.459
neuron maturationGO:0042551290.458
regulation of establishment of protein localization to plasma membraneGO:0090003120.456
cellular response to glucose stimulusGO:0071333450.451
negative regulation of cellular component organizationGO:00511291940.450
regulation of endocytosisGO:0030100690.436
Fly
response to monosaccharideGO:0034284670.425
protein localization to membraneGO:00726571080.425
regulation of cellular component biogenesisGO:00440871810.418
regulation of hormone secretionGO:0046883880.416
establishment of organelle localizationGO:00516561220.412
Fly
positive regulation of nervous system developmentGO:00519622210.408
regulation of protein localization to plasma membraneGO:1903076130.392
neurotransmitter transportGO:0006836760.392
plasma membrane organizationGO:0007009900.392
positive regulation of cellular component biogenesisGO:0044089940.385
learningGO:0007612980.371
regulation of membrane potentialGO:00423911920.368
synapse organizationGO:00508081250.360
regulation of ion transportGO:00432692150.359
endomembrane system organizationGO:00102561470.358
regulation of peptide hormone secretionGO:0090276750.340
neuron neuron synaptic transmissionGO:0007270690.338
single organism cell adhesionGO:00986021560.330
positive regulation of synapse maturationGO:009012970.300
peptide hormone secretionGO:00300721090.298
synaptic vesicle endocytosisGO:0048488190.295
Fly
cellular glucose homeostasisGO:0001678520.284
positive regulation of endocytosisGO:0045807420.283
Fly
single organismal cell cell adhesionGO:00163371310.263
cellular response to hexose stimulusGO:0071331470.262
negative regulation of cell projection organizationGO:0031345560.260
neurotransmitter secretionGO:0007269620.257
synapse assemblyGO:0007416560.257
establishment of protein localization to plasma membraneGO:0090002340.248
adult behaviorGO:00305341350.217
guanylate kinase associated protein clusteringGO:009711720.209
regulation of hormone levelsGO:00108172110.187
axonogenesisGO:00074092740.186
regulation of synaptic transmission glutamatergicGO:0051966190.183
regulation of filopodium assemblyGO:0051489130.181
regulation of cellular ketone metabolic processGO:0010565660.175
regulation of secretionGO:00510462740.174
cellular homeostasisGO:00197252400.168
cognitionGO:00508901490.167
regulation of protein localizationGO:00328802310.163
neuron projection guidanceGO:00974851410.162
learned vocalization behavior or vocal learningGO:009859810.162
Human
regulation of platelet derived growth factor receptor signaling pathwayGO:001064090.159
protein localization to plasma membraneGO:0072659570.151
regulation of transporter activityGO:0032409570.143
regulation of establishment of protein localizationGO:00702011810.143
regulation of platelet derived growth factor receptor alpha signaling pathwayGO:200058320.138
chemotaxisGO:00069352470.123
endocytosisGO:00068971680.109
Fly
filopodium assemblyGO:0046847190.105
vocalization behaviorGO:007162570.103
Human
peptide secretionGO:00027901140.098
platelet derived growth factor receptor signaling pathwayGO:0048008320.092
lymphocyte mediated immunityGO:00024491390.090
immune effector processGO:00022523210.081
ear developmentGO:00435832000.076
negative regulation of cellular protein metabolic processGO:00322692470.074
inorganic cation transmembrane transportGO:00986622070.071
cell maturationGO:00484691270.071
axon guidanceGO:00074111410.070
regulation of protein serine threonine kinase activityGO:00719001570.070
regulation of neuron projection developmentGO:00109751690.068
fatty acid metabolic processGO:00066311210.068
negative regulation of intracellular signal transductionGO:19025321670.065
negative regulation of protein metabolic processGO:00512482820.064
leukocyte mediated immunityGO:00024431740.063
cation transportGO:00068123990.063
positive regulation of kinase activityGO:00336741550.061
dendrite developmentGO:00163581150.058
regulation of glucose metabolic processGO:0010906600.057
cellular lipid metabolic processGO:00442553230.056
negative regulation of platelet derived growth factor receptor alpha signaling pathwayGO:200058420.056
positive regulation of protein modification processGO:00314012990.055
regulation of transferase activityGO:00513382630.054
gluconeogenesisGO:0006094390.054
carbohydrate metabolic processGO:00059752300.053
metanephric glomerular visceral epithelial cell developmentGO:007224920.051
adaptive immune responseGO:00022501550.051
multi organism behaviorGO:0051705620.051
Human
negative regulation of protein phosphorylationGO:00019331260.050
lipid oxidationGO:0034440290.050
motor neuron axon guidanceGO:0008045260.050
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.050
negative regulation of platelet derived growth factor receptor signaling pathwayGO:001064270.048
negative regulation of carbohydrate metabolic processGO:0045912190.047
negative regulation of cellular amino acid metabolic processGO:004576300.046
regulation of cellular amino acid metabolic processGO:000652150.046
positive regulation of protein phosphorylationGO:00019342420.045
protein heterooligomerizationGO:0051291140.045
positive regulation of glucose transportGO:0010828160.045
cellular chemical homeostasisGO:00550822150.043
hexose biosynthetic processGO:0019319390.043
regulation of mapk cascadeGO:00434082480.042
negative regulation of phosphorylationGO:00423261660.041
negative regulation of gluconeogenesisGO:004572190.041
regulation of gluconeogenesisGO:0006111300.041
hexose metabolic processGO:0019318980.041
regulation of lipid metabolic processGO:00192161180.040
monosaccharide biosynthetic processGO:0046364440.040
activation of immune responseGO:00022531380.039
regulation of feeding behaviorGO:006025930.039
regulation of fatty acid metabolic processGO:0019217280.039
regulation of cell migrationGO:00303342190.038
regulation of neuron differentiationGO:00456642810.038
hormone secretionGO:00468791280.035
carbohydrate biosynthetic processGO:0016051740.035
neuroblast division in subventricular zoneGO:002184920.034
regulation of protein kinase activityGO:00458592320.034
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clusteringGO:009711330.033
detection of mechanical stimulus involved in sensory perception of painGO:005096640.033
nitrogen compound transportGO:00717052710.032
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.031
cellular ketone metabolic processGO:0042180840.031
monocarboxylic acid catabolic processGO:0072329270.031
sensory perceptionGO:00076002450.030
epithelial cell differentiation involved in kidney developmentGO:0035850230.029
regulation of response to woundingGO:19030341890.029
cation transmembrane transportGO:00986552660.029
cellular carbohydrate metabolic processGO:00442621190.029
regulation of neuron deathGO:19012141340.028
negative regulation of phosphorus metabolic processGO:00105631840.028
fatty acid catabolic processGO:0009062250.027
regulation of cell activationGO:00508652890.027
monocarboxylic acid metabolic processGO:00327871910.026
regulation of synaptic plasticityGO:0048167870.026
platelet derived growth factor receptor alpha signaling pathwayGO:003579030.026
regulation of anatomical structure sizeGO:00900661780.026
regulation of vesicle mediated transportGO:00606271390.026
Fly
lipid modificationGO:0030258650.026
positive regulation of fatty acid metabolic processGO:004592380.025
sensory organ morphogenesisGO:00905962420.025
glucose metabolic processGO:0006006920.025
organic anion transportGO:00157111370.025
response to radiationGO:00093141650.025
b cell mediated immunityGO:0019724710.024
negative regulation of protein modification processGO:00314001630.024
calcium ion transportGO:00068161590.024
regulation of cell morphogenesis involved in differentiationGO:00107691510.023
exocytosisGO:00068871210.023
regulation of neurotransmitter secretionGO:0046928290.023
response to painGO:0048265260.023
regulation of cell motilityGO:20001452360.023
positive regulation of transferase activityGO:00513471670.023
positive regulation of glucose importGO:0046326140.023
regulation of carbohydrate metabolic processGO:0006109750.023
regulation of glucose importGO:0046324260.022
divalent inorganic cation transportGO:00725111780.022
inorganic ion transmembrane transportGO:00986602340.022
inflammatory responseGO:00069542440.022
positive regulation of protein serine threonine kinase activityGO:00719021060.022
protein catabolic processGO:00301632210.022
amine metabolic processGO:0009308450.021
inner ear morphogenesisGO:00424721010.021
regulation of glucose transportGO:0010827320.021
cellular response to peptide hormone stimulusGO:0071375920.021
locomotory behaviorGO:00076261950.020
regulation of defense responseGO:00313472330.020
fatty acid beta oxidationGO:0006635160.020
cellular potassium ion transportGO:0071804430.020
protein oligomerizationGO:0051259670.020
cell differentiation involved in metanephros developmentGO:0072202120.020
regulation of kinase activityGO:00435492490.019
camera type eye developmentGO:00430102660.019
negative regulation of cellular carbohydrate metabolic processGO:0010677190.019
cell activation involved in immune responseGO:00022631260.019
ribonucleotide metabolic processGO:00092592910.018
positive regulation of cell developmentGO:00107202370.018
multicellular organismal signalingGO:0035637910.018
response to endoplasmic reticulum stressGO:0034976530.018
cellular response to insulin stimulusGO:0032869780.018
small molecule catabolic processGO:0044282710.018
nucleobase containing small molecule metabolic processGO:00550863520.018
negative regulation of cellular amine metabolic processGO:003323910.017
cellular lipid catabolic processGO:0044242520.017
response to peptideGO:19016521360.017
organic acid catabolic processGO:0016054510.017
negative regulation of fat cell differentiationGO:0045599360.017
cellular response to peptideGO:1901653920.017
rhythmic processGO:00485111740.017
positive regulation of protein kinase activityGO:00458601440.017
inter male aggressive behaviorGO:000212130.017
positive regulation of rac gtpase activityGO:0032855140.017
response to organonitrogen compoundGO:00102432460.017
positive regulation of jnk cascadeGO:0046330460.017
cation homeostasisGO:00550802120.017
activation of meiosis involved in egg activationGO:006046620.017
glucose transportGO:0015758560.016
male courtship behaviorGO:000804920.016
renal system developmentGO:00720012250.016
lipid catabolic processGO:0016042690.016
cellular amine metabolic processGO:0044106440.016
regulation of neuron apoptotic processGO:00435231220.015
regulation of organelle organizationGO:00330432890.015
peptidyl amino acid modificationGO:00181933360.015
negative regulation of cell motilityGO:2000146610.015
spinal cord developmentGO:0021510810.015
oocyte anterior posterior axis specificationGO:000731420.015
respiratory system developmentGO:00605411900.015
response to auditory stimulusGO:001099650.015
Human
maternal determination of anterior posterior axis embryoGO:000835820.015
response to peptide hormoneGO:00434341270.015
ribonucleoside catabolic processGO:00424542060.015
negative regulation of growthGO:0045926990.015
nucleoside phosphate metabolic processGO:00067533380.014
protein modification by small protein conjugation or removalGO:00706472070.014
carboxylic acid catabolic processGO:0046395510.014
retina development in camera type eyeGO:00600411190.014
regulation of cellular catabolic processGO:00313292420.014
negative regulation of response to woundingGO:1903035770.014
regulation of system processGO:00440572000.014
negative regulation of kinase activityGO:0033673810.013
sensory system developmentGO:004888030.013
negative regulation of cell developmentGO:00107211690.013
inner ear receptor cell developmentGO:0060119390.013
metanephric mesenchymal cell migrationGO:003578920.013
detection of stimulus involved in sensory perceptionGO:0050906440.013
lymphocyte activation involved in immune responseGO:0002285930.013
cellular amino acid metabolic processGO:00065201030.013
renal filtration cell differentiationGO:0061318100.013
glycosyl compound catabolic processGO:19016582060.013
potassium ion transmembrane transportGO:0071805430.013
sodium ion transmembrane transportGO:0035725490.013
glycosyl compound metabolic processGO:19016572460.012
reactive oxygen species metabolic processGO:0072593840.012
negative regulation of protein serine threonine kinase activityGO:0071901490.012
complement activationGO:0006956160.012
sensory perception of painGO:0019233470.012
immunoglobulin mediated immune responseGO:0016064690.012
protein polymerizationGO:0051258570.012
epithelial cell developmentGO:00020641590.012
calcium ion transmembrane transportGO:0070588850.012
cell migration involved in metanephros developmentGO:003578820.012
regulation of cellular component sizeGO:00325351210.012
regulation of voltage gated calcium channel activityGO:190138540.012
renal system processGO:0003014480.012
directional locomotionGO:003305830.012
engulfment of apoptotic cellGO:004365230.012
methylationGO:00322591340.012
humoral immune response mediated by circulating immunoglobulinGO:0002455140.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
detection of abiotic stimulusGO:0009582600.012
cytokine productionGO:00018163190.012
response to insulinGO:00328681000.012
glomerular visceral epithelial cell differentiationGO:0072112100.012
glomerular epithelium developmentGO:0072010110.012
monosaccharide transportGO:0015749580.011
aromatic compound catabolic processGO:00194392860.011
negative regulation of nervous system developmentGO:00519611560.011
multicellular organismal homeostasisGO:00488711640.011
sensory perception of mechanical stimulusGO:00509541070.011
purine ribonucleoside metabolic processGO:00461282410.011
cellular response to lipidGO:00713961450.011
macromolecule catabolic processGO:00090572810.011
regulation of metal ion transportGO:00109591060.011
response to oxidative stressGO:00069791230.011
divalent metal ion transportGO:00708381720.011
purine ribonucleoside triphosphate metabolic processGO:00092052200.011
t cell activationGO:00421102890.011
cell migration involved in kidney developmentGO:003578730.011
cellular response to organonitrogen compoundGO:00714171450.011
facioacoustic ganglion developmentGO:190337530.011
glomerular epithelial cell developmentGO:007231060.011
regulation of body fluid levelsGO:00508781620.011
detection of external stimulusGO:0009581610.011
response to acid chemicalGO:00011011110.011
purine containing compound metabolic processGO:00725213110.011
covalent chromatin modificationGO:00165691630.011
neuron apoptotic processGO:00514021420.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
nucleoside metabolic processGO:00091162460.011
actin filament organizationGO:00070151130.011
negative regulation of defense responseGO:0031348770.010
lateral inhibitionGO:004633110.010
negative regulation of mapk cascadeGO:0043409650.010
regulation of synaptic growth at neuromuscular junctionGO:000858240.010
metanephric glomerular epithelium developmentGO:007224430.010
regulation of fat cell differentiationGO:0045598810.010
cellular nitrogen compound catabolic processGO:00442702800.010

Nrxn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
brain diseaseDOID:93600.030
nervous system diseaseDOID:86300.030
central nervous system diseaseDOID:33100.030
disease of cellular proliferationDOID:1456600.022
cancerDOID:16200.022
organ system cancerDOID:005068600.022
electroclinical syndromeDOID:005070100.017
epilepsy syndromeDOID:182600.017
neurodegenerative diseaseDOID:128900.012
gastrointestinal system cancerDOID:311900.011