Mus musculus

291 known processes

Ptpn11

protein tyrosine phosphatase, non-receptor type 11

(Aliases: AW536184,PTP1D,2700084A17Rik,PTP2C,Shp2,SAP-2,SHP-2,Syp,SH-PTP3,SH-PTP2)

Ptpn11 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tyrosine phosphorylation of stat5 proteinGO:004250691.000
regulation of transferase activityGO:00513382631.000
embryonic placenta developmentGO:0001892981.000
t cell activationGO:00421102890.999
Mouse
negative regulation of cellular amino acid metabolic processGO:004576300.999
negative regulation of t cell proliferationGO:0042130380.999
Mouse
regulation of mapk cascadeGO:00434082480.999
regulation of cellular ketone metabolic processGO:0010565660.999
cellular ketone metabolic processGO:0042180840.999
olfactory learningGO:000835520.998
myelination in peripheral nervous systemGO:0022011190.998
cardiac muscle tissue developmentGO:00487381300.998
regulation of cellular amine metabolic processGO:0033238200.998
layer formation in cerebral cortexGO:0021819130.998
stem cell developmentGO:00488642190.998
amine metabolic processGO:0009308450.998
regulation of protein kinase activityGO:00458592320.997
muscle tissue developmentGO:00605373080.997
cellular amine metabolic processGO:0044106440.997
regulation of erk1 and erk2 cascadeGO:0070372710.997
regulation of jak stat cascadeGO:0046425340.996
regulation of lymphocyte proliferationGO:00506701170.996
Mouse
positive regulation of glial cell proliferationGO:006025240.996
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.996
synaptic transmissionGO:00072683290.996
regulation of receptor activityGO:0010469410.996
positive regulation of mapk cascadeGO:00434101700.996
cytokine mediated signaling pathwayGO:00192211150.995
negative regulation of immature t cell proliferationGO:003308730.994
ras protein signal transductionGO:0007265770.994
regulation of kinase activityGO:00435492490.994
regulation of lymphocyte differentiationGO:00456191070.994
Mouse
labyrinthine layer developmentGO:0060711490.993
dna metabolic processGO:00062593030.993
positive regulation of map kinase activityGO:0043406840.993
peptidyl amino acid modificationGO:00181933360.993
Mouse
small gtpase mediated signal transductionGO:0007264970.993
cardiocyte differentiationGO:0035051870.993
epithelial cell developmentGO:00020641590.992
Fly
negative regulation of epithelial cell proliferationGO:0050680640.992
ventricular septum morphogenesisGO:0060412270.992
carbon catabolite activation of transcriptionGO:004599140.992
regulation of protein serine threonine kinase activityGO:00719001570.991
negative regulation of cell proliferationGO:00082852960.991
Mouse
regulation of leukocyte differentiationGO:19021051590.991
Mouse
jak stat cascadeGO:0007259420.991
cellular response to hormone stimulusGO:00328701500.991
activation of mapk activity involved in innate immune responseGO:003541920.990
heart trabecula formationGO:0060347140.990
stem cell maintenanceGO:00198271300.990
regulation of secretionGO:00510462740.990
response to organonitrogen compoundGO:00102432460.989
Human
regulation of t cell activationGO:00508631700.989
Mouse
erbb signaling pathwayGO:0038127320.988
mapk cascadeGO:00001652810.988
muscle cell proliferationGO:0033002520.987
regulation of lymphocyte activationGO:00512492400.987
Mouse
axon ensheathmentGO:0008366760.987
lactationGO:0007595250.987
negative regulation of anoikisGO:200081120.987
mesenchyme developmentGO:00604851520.987
negative regulation of protein phosphorylationGO:00019331260.986
Mouse
leukocyte differentiationGO:00025213420.986
Mouse
neuron migrationGO:00017641220.986
positive regulation of kinase activityGO:00336741550.986
gland developmentGO:00487323300.986
blood vessel morphogenesisGO:00485142850.985
regulation of cellular amino acid metabolic processGO:000652150.985
t cell proliferationGO:00420981200.985
Mouse
positive regulation of growthGO:00459271040.984
ensheathment of neuronsGO:0007272760.983
clara cell differentiationGO:006048640.983
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043640.983
rac protein signal transductionGO:0016601130.983
stem cell differentiationGO:00488632680.983
cellular amino acid metabolic processGO:00065201030.983
regulation of protein targetingGO:1903533610.983
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.982
Mouse
mitral valve morphogenesisGO:000318340.981
gliogenesisGO:00420631410.980
myelinationGO:0042552740.980
cardiac chamber developmentGO:00032051080.980
response to peptide hormoneGO:00434341270.980
Human
formation of radial glial scaffoldsGO:002194340.978
peptidyl tyrosine phosphorylationGO:00181081430.978
Mouse
endodermal cell fate specificationGO:000171440.977
heart trabecula morphogenesisGO:0061384260.976
fibroblast growth factor receptor signaling pathwayGO:0008543460.976
Fly
striated muscle tissue developmentGO:00147062930.975
organ growthGO:00352651170.975
cardiac muscle cell differentiationGO:0055007690.974
peptidyl tyrosine modificationGO:00182121450.974
Mouse
epithelial tube morphogenesisGO:00605623030.973
Zebrafish
myeloid cell differentiationGO:00300992330.973
regulation of t cell differentiationGO:0045580830.973
epidermal growth factor receptor signaling pathwayGO:0007173280.973
positive regulation of transferase activityGO:00513471670.972
pyramidal neuron migrationGO:002185210.972
schwann cell differentiationGO:0014037260.972
striated muscle cell proliferationGO:0014855390.971
cardioblast migration to the midline involved in heart field formationGO:006097510.971
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.971
muscle cell differentiationGO:00426922610.971
morphogenesis of a branching structureGO:00017632030.970
platelet derived growth factor receptor signaling pathwayGO:0048008320.970
negative regulation of cellular protein metabolic processGO:00322692470.970
Mouse
learning or memoryGO:00076111480.970
regulation of secretion by cellGO:19035302490.969
oocyte axis specificationGO:000730920.969
response to insulinGO:00328681000.968
Human
positive regulation of cardioblast differentiationGO:005189130.968
axon guidanceGO:00074111410.967
urogenital system developmentGO:00016552610.966
cellular response to growth factor stimulusGO:00713631970.965
placenta developmentGO:00018901400.965
positive regulation of nervous system developmentGO:00519622210.964
positive regulation of heart growthGO:0060421180.963
negative regulation of protein modification processGO:00314001630.963
Mouse
regulation of insulin receptor signaling pathwayGO:0046626210.962
negative regulation of lymphocyte proliferationGO:0050672450.962
Mouse
cardiac endothelial cell differentiationGO:000334840.962
cellular response to epidermal growth factor stimulusGO:007136440.961
apoptotic signaling pathwayGO:00971903060.960
negative regulation of phosphorus metabolic processGO:00105631840.960
Mouse
heart morphogenesisGO:00030071780.960
Zebrafish
response to organic cyclic compoundGO:00140701980.959
negative regulation of translational initiationGO:004594740.959
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.959
regulation of sequence specific dna binding transcription factor activityGO:00510901060.958
embryonic heart tube left right pattern formationGO:006097150.958
sensory organ morphogenesisGO:00905962420.958
Fly
negative regulation of molecular functionGO:00440922580.956
Mouse
carbon catabolite repression of transcription from rna polymerase ii promoterGO:000043710.956
tyrosine phosphorylation of stat proteinGO:0007260230.956
columnar cuboidal epithelial cell differentiationGO:0002065820.954
Fly
epithelial cell proliferationGO:00506731740.954
response to peptideGO:19016521360.954
Human
negative regulation of ras protein signal transductionGO:0046580180.954
negative regulation of phosphorylationGO:00423261660.954
Mouse
germ cell developmentGO:00072811850.954
Fly
lens development in camera type eyeGO:0002088620.954
associative learningGO:0008306610.953
cardiac septum developmentGO:0003279590.953
positive regulation of cellular amine metabolic processGO:003324050.953
mesenchymal cell developmentGO:0014031930.953
telencephalon developmentGO:00215371860.950
atrial septum primum morphogenesisGO:000328930.950
endodermal cell fate commitmentGO:0001711120.950
regulation of cardioblast differentiationGO:005189030.949
negative regulation of wnt signaling pathway involved in heart developmentGO:000330840.949
oocyte differentiationGO:0009994350.948
cognitionGO:00508901490.948
cardiac muscle tissue morphogenesisGO:0055008440.948
outflow tract morphogenesisGO:0003151530.947
mesenchymal cell differentiationGO:00487621070.947
g protein coupled receptor signaling pathwayGO:00071862430.946
transcriptional activation by promoter enhancer loopingGO:007173320.945
cellular response to insulin stimulusGO:0032869780.945
Human
blood circulationGO:00080151950.944
septum primum developmentGO:000328440.943
peripheral nervous system developmentGO:0007422530.943
response to growth factorGO:00708481980.943
regulation of intracellular transportGO:00323861590.943
cerebral cortex developmentGO:0021987860.942
negative regulation of glial cell proliferationGO:006025340.941
regulation of protein localizationGO:00328802310.940
spongiotrophoblast layer developmentGO:0060712150.940
regulation of cell activationGO:00508652890.939
Mouse
positive regulation of transcription from rna polymerase iii promoterGO:004594510.939
immune response activating signal transductionGO:00027571160.938
Mouse
regulation of tyrosine phosphorylation of stat proteinGO:0042509200.937
response to corticosteroidGO:0031960200.937
lymphocyte differentiationGO:00300982420.936
Mouse
positive regulation of neuron differentiationGO:00456661410.935
cell proliferation involved in outflow tract morphogenesisGO:006132540.935
neuron projection extensionGO:1990138640.935
multicellular organism growthGO:00352641610.934
metanephric glomerular mesangium developmentGO:007222330.934
branching morphogenesis of an epithelial tubeGO:00487541590.933
regulation of myeloid leukocyte differentiationGO:0002761580.932
atrial cardiac muscle cell differentiationGO:005501120.932
positive regulation of vasoconstrictionGO:004590740.931
mitotic cell cycleGO:00002781950.931
muscle cell developmentGO:00550011330.931
response to epidermal growth factorGO:007084940.929
neuronal action potentialGO:0019228540.929
cerebral cortex cell migrationGO:0021795440.928
response to steroid hormoneGO:0048545560.927
autophagyGO:0006914450.925
cardiac muscle tissue regenerationGO:006102610.924
trophoblast giant cell differentiationGO:0060707150.922
myeloid leukocyte differentiationGO:00025731190.922
atrial ventricular junction remodelingGO:000329420.922
cellular response to cytokine stimulusGO:00713451890.921
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.921
regulation of nucleocytoplasmic transportGO:0046822730.920
cardiac muscle cell developmentGO:0055013390.920
regionalizationGO:00030023370.920
Fly
negative regulation of cellular amine metabolic processGO:003323910.918
ovarian follicle developmentGO:0001541400.918
carbon catabolite regulation of transcriptionGO:004599040.918
positive regulation of leukocyte differentiationGO:1902107860.917
mitotic cell cycle processGO:19030471590.917
telencephalon cell migrationGO:0022029550.916
cell adhesionGO:00071553290.913
positive regulation of apoptotic signaling pathwayGO:2001235950.912
negative regulation of nervous system developmentGO:00519611560.912
neuron apoptotic processGO:00514021420.911
negative regulation of neurotransmitter transportGO:005158970.908
embryonic heart tube anterior posterior pattern specificationGO:003505430.907
negative regulation of release of cytochrome c from mitochondriaGO:009020160.906
embryonic hemopoiesisGO:0035162230.905
heart field specificationGO:000312860.905
neural crest cell differentiationGO:0014033540.904
cardiac muscle tissue growthGO:0055017370.904
immune effector processGO:00022523210.903
Mouse
neural crest cell migrationGO:0001755320.903
peptide hormone secretionGO:00300721090.902
positive regulation of ras protein signal transductionGO:0046579130.901
cardiac chamber morphogenesisGO:0003206930.901
positive regulation of cardiac muscle tissue growthGO:0055023150.900
intracellular protein transportGO:00068862040.899
insulin receptor signaling pathwayGO:0008286490.898
cell differentiation involved in embryonic placenta developmentGO:0060706260.898
neural crest cell developmentGO:0014032480.898
cerebral cortex radial glia guided migrationGO:0021801170.897
forebrain developmentGO:00309003020.896
gonad developmentGO:00084061410.893
heart growthGO:0060419450.892
regulation of muscle cell apoptotic processGO:0010660170.892
nucleocytoplasmic transportGO:00069131390.892
kidney epithelium developmentGO:00720731210.891
regulation of membrane potentialGO:00423911920.890
skeletal muscle cell differentiationGO:0035914660.889
regulation of map kinase activityGO:00434051200.888
mitochondrion organizationGO:00070051340.888
regulation of cardiac muscle tissue developmentGO:0055024310.887
pallium developmentGO:00215431200.887
protein kinase b signalingGO:0043491740.886
activation of mapkk activityGO:0000186150.885
eye photoreceptor cell differentiationGO:0001754410.884
Fly
negative regulation of transferase activityGO:0051348850.884
Mouse
response to alcoholGO:0097305480.883
negative regulation of kinase activityGO:0033673810.881
Mouse
cellular response to amino acid stimulusGO:0071230290.881
regulation of cardiac muscle cell proliferationGO:0060043230.881
growth plate cartilage chondrocyte developmentGO:000343130.880
schwann cell developmentGO:0014044220.879
cell fate commitmentGO:00451652100.879
Fly
regulation of apoptotic process involved in outflow tract morphogenesisGO:190225620.879
cellular response to glucocorticoid stimulusGO:0071385130.877
regulation of feeding behaviorGO:006025930.876
cardioblast migrationGO:000326010.875
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.871
regulation of blood circulationGO:1903522930.870
central nervous system morphogenesisGO:002155120.870
positive regulation of cell cycle processGO:0090068610.869
regulation of ras protein signal transductionGO:00465781140.865
cardiac muscle cell proliferationGO:0060038310.864
positive regulation of transcription via serum response element bindingGO:001073510.864
ventricular trabecula myocardium morphogenesisGO:0003222110.863
regulation of hydrolase activityGO:00513362460.863
regulation of epidermal cell differentiationGO:0045604210.862
regulation of mast cell differentiationGO:006037530.861
positive regulation of axon extensionGO:0045773200.860
regulation of stat protein import into nucleusGO:200036420.860
mammary gland morphogenesisGO:0060443540.860
cytokine productionGO:00018163190.857
regulation of anoikisGO:200020920.857
actin filament organizationGO:00070151130.855
cellular response to organonitrogen compoundGO:00714171450.855
Human
positive regulation of tyrosine phosphorylation of stat5 proteinGO:004252360.852
nuclear transportGO:00511691390.852
regulation of cardiac cell fate specificationGO:200004310.851
carbohydrate metabolic processGO:00059752300.851
forebrain neuron differentiationGO:0021879520.851
regulation of tyrosine phosphorylation of stat5 proteinGO:004252280.849
second messenger mediated signalingGO:0019932730.848
cellular response to abiotic stimulusGO:0071214560.844
positive regulation of protein modification processGO:00314012990.844
learningGO:0007612980.842
negative regulation of receptor activityGO:200027250.842
directional locomotionGO:003305830.842
activation of janus kinase activityGO:004297620.837
regulation of neuron differentiationGO:00456642810.837
Fly
synapse organizationGO:00508081250.836
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.835
circulatory system processGO:00030131970.834
regulation of establishment of protein localizationGO:00702011810.834
g1 s transition of mitotic cell cycleGO:0000082570.834
regulation of neuronal synaptic plasticityGO:0048168300.834
actin cytoskeleton organizationGO:00300362200.832
mammary gland epithelium developmentGO:0061180650.832
chromatin organizationGO:00063252060.831
establishment of organelle localizationGO:00516561220.828
negative regulation of leukocyte differentiationGO:1902106510.827
cerebral cortex radially oriented cell migrationGO:0021799310.823
signal transduction in absence of ligandGO:0038034550.822
purine ribonucleotide catabolic processGO:00091542080.822
kidney developmentGO:00018222130.821
cellular response to peptideGO:1901653920.821
Human
regulation of t cell proliferationGO:0042129920.820
Mouse
regulation of intracellular protein transportGO:0033157820.820
negative regulation of protein metabolic processGO:00512482820.819
Mouse
negative regulation of osteoclast differentiationGO:0045671120.818
axon target recognitionGO:000741240.818
camera type eye developmentGO:00430102660.817
oocyte constructionGO:000730820.816
negative regulation of phosphate metabolic processGO:00459361840.815
Mouse
negative regulation of apoptotic signaling pathwayGO:20012341040.815
endocardial cell differentiationGO:006095640.814
positive regulation of protein kinase activityGO:00458601440.813
transmission of nerve impulseGO:0019226760.811
cardiac ventricle developmentGO:0003231830.810
heart valve developmentGO:0003170230.810
positive regulation of cell migrationGO:00303351090.810
neuron neuron synaptic transmissionGO:0007270690.810
regulation of protein tyrosine kinase activityGO:0061097170.807
neuron deathGO:00709971540.804
positive regulation of cell growthGO:0030307330.803
regulation of peptidyl tyrosine phosphorylationGO:0050730930.801
Mouse
cell agingGO:0007569350.801
multicellular organismal signalingGO:0035637910.799
regulation of cellular catabolic processGO:00313292420.799
protein kinase c activating g protein coupled receptor signaling pathwayGO:000720540.798
av node cell to bundle of his cell communicationGO:008606720.796
regulation of osteoblast differentiationGO:0045667670.796
tor signalingGO:0031929210.795
adaptive immune responseGO:00022501550.795
Mouse
regulation of synaptic plasticityGO:0048167870.794
cytoplasmic transportGO:00164822340.794
regulation of cardiac muscle tissue growthGO:0055021260.793
respiratory system developmentGO:00605411900.792
Fly
negative regulation of cell fate specificationGO:000999640.787
angiogenesisGO:00015252010.786
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.785
regulation of protein import into nucleusGO:0042306520.784
negative regulation of protein serine threonine kinase activityGO:0071901490.781
Mouse
canonical wnt signaling pathway involved in heart developmentGO:006131630.779
erk1 and erk2 cascadeGO:0070371770.778
negative regulation of muscle cell apoptotic processGO:001065690.777
lung developmentGO:00303241640.775
positive regulation of transcription by glucoseGO:004601630.775
regulation of cell migrationGO:00303342190.773
epidermis developmentGO:00085441870.771
aortic valve morphogenesisGO:000318040.767
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.766
embryonic organ morphogenesisGO:00485622760.766
Zebrafish
response to fibroblast growth factorGO:0071774470.765
Fly
chondrocyte hypertrophyGO:000341540.764
organ regenerationGO:003110020.763
axonogenesisGO:00074092740.761
negative regulation of cardiac muscle tissue developmentGO:005502680.761
ventricular cardiac muscle cell differentiationGO:0055012170.760
monocyte differentiationGO:003022490.759
regulation of system processGO:00440572000.759
positive regulation of erk1 and erk2 cascadeGO:0070374470.758
morphogenesis of a branching epitheliumGO:00611381930.758
regulation of smad protein import into nucleusGO:006039030.758
negative regulation of map kinase activityGO:0043407340.757
Mouse
metanephric nephron tubule formationGO:007228940.756
regulation of cell cycle processGO:00105641600.756
negative regulation of myeloid leukocyte differentiationGO:0002762200.756
germ line stem cell divisionGO:004207820.755
hindbrain radial glia guided cell migrationGO:0021932120.751
regulation of cell motilityGO:20001452360.750
protein catabolic processGO:00301632210.749
embryonic heart tube developmentGO:0035050650.749
Zebrafish
cell type specific apoptotic processGO:00972852680.749
mechanoreceptor differentiationGO:0042490670.749
branching involved in mammary gland duct morphogenesisGO:0060444270.747
regulation of epithelial cell migrationGO:0010632350.745
multi organism reproductive behaviorGO:0044705290.745
regulation of synaptic growth at neuromuscular junctionGO:000858240.744
negative regulation of epidermal growth factor receptor signaling pathwayGO:004205960.744
cell fate specificationGO:0001708720.742
maternal process involved in female pregnancyGO:0060135320.740
growth plate cartilage developmentGO:0003417140.738
regulation of heart growthGO:0060420310.737
negative regulation of peptide hormone secretionGO:0090278160.737
cardiac myofibril assemblyGO:0055003120.736
action potentialGO:0001508780.735
protein targetingGO:00066051430.734
regulation of myoblast differentiationGO:0045661290.732
wnt signaling pathway involved in kidney developmentGO:006128920.730
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.729
positive regulation of programmed cell deathGO:00430682180.728
pigment metabolic processGO:0042440320.728
ventricular septum developmentGO:0003281420.727
alpha beta t cell differentiationGO:0046632690.726
cellular lipid metabolic processGO:00442553230.725
positive regulation of osteoblast proliferationGO:003369090.724
positive regulation of cell developmentGO:00107202370.724
negative regulation of cell developmentGO:00107211690.724
mast cell differentiationGO:006037450.723
positive regulation of cardiac muscle cell proliferationGO:0060045150.722
protein import into nucleusGO:0006606950.722
prostate gland epithelium morphogenesisGO:0060740310.721
mesonephric tubule developmentGO:0072164940.721
atrioventricular valve morphogenesisGO:0003181130.721
erythrocyte differentiationGO:0030218880.720
positive regulation of epithelial cell proliferationGO:0050679680.720
digestive tract morphogenesisGO:00485461470.720
Zebrafish
digestive system developmentGO:00551232000.720
Zebrafish
mammary gland lobule developmentGO:0061377220.719
cellular response to radiationGO:0071478280.714
glial cell differentiationGO:00100011310.709
cardiac muscle fiber developmentGO:004873940.709
astrocyte activationGO:004814320.708
liver developmentGO:0001889660.707
negative regulation of mapk cascadeGO:0043409650.705
Mouse
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.704
prostate gland stromal morphogenesisGO:006074120.703
regulation of defense responseGO:00313472330.703
regulation of t cell differentiation in thymusGO:0033081240.702
cardiac conduction system developmentGO:0003161120.702
regulation of cell migration involved in sprouting angiogenesisGO:009004940.701
negative regulation of cellular response to insulin stimulusGO:1900077160.699
rhodopsin mediated signaling pathwayGO:001605640.698
negative regulation of immune system processGO:00026832090.696
Mouse
oligodendrocyte differentiationGO:0048709530.694
negative regulation of neuron projection developmentGO:0010977500.694
positive regulation of lymphocyte differentiationGO:0045621610.693
spermatid differentiationGO:00485151150.693
organonitrogen compound catabolic processGO:19015652640.692
regulation of heart contractionGO:0008016770.692
positive regulation of fibroblast proliferationGO:0048146200.692
cellular response to steroid hormone stimulusGO:0071383330.691
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.689
regulation of epidermal growth factor activated receptor activityGO:000717670.687
positive regulation of cell cycleGO:0045787920.684
regulation of transcription from rna polymerase iii promoterGO:000635920.683
mitral valve developmentGO:000317440.679
extracellular matrix dependent thymocyte migrationGO:007268010.676
fused antrum stageGO:004816510.675
positive regulation of stem cell proliferationGO:2000648590.669
epithelial cell differentiation involved in prostate gland developmentGO:0060742130.669
mammary gland epithelial cell differentiationGO:0060644130.669
vesicle localizationGO:0051648860.668
leukocyte proliferationGO:00706611720.666
Mouse
negative regulation of lymphocyte apoptotic processGO:0070229240.666
positive regulation of cellular amino acid metabolic processGO:004576430.664
regulation of epidermal growth factor receptor signaling pathwayGO:0042058130.664
ameboidal type cell migrationGO:00016671280.664
Fly
response to drugGO:0042493750.664
lymphocyte homeostasisGO:0002260640.663
single organism cell adhesionGO:00986021560.660
Mouse
negative regulation of cell activationGO:00508661110.657
Mouse
eye photoreceptor cell developmentGO:0042462310.657
Fly
t cell differentiation in thymusGO:0033077770.655
positive regulation of intracellular protein transportGO:0090316420.655
glycosyl compound catabolic processGO:19016582060.654
lateral mesoderm morphogenesisGO:004836930.654
lung inductionGO:006049230.654
cellular response to acid chemicalGO:0071229680.652
regulation of hippo signalingGO:003533010.652
positive regulation of transcription from rna polymerase ii promoter by glucoseGO:000043230.651
cellular nitrogen compound catabolic processGO:00442702800.649
positive regulation of auditory receptor cell differentiationGO:004560910.649
microtubule cytoskeleton organizationGO:00002261570.649
positive regulation of nucleocytoplasmic transportGO:0046824300.648
regenerationGO:0031099380.647
negative regulation of endothelial cell proliferationGO:000193780.646
protein autophosphorylationGO:0046777610.643
muscle cell apoptotic processGO:0010657180.642
regulation of gtp catabolic processGO:00331241130.641
segmentationGO:0035282930.638
Fly
negative regulation of transcription from rna polymerase ii promoter in response to stressGO:009720110.637
regulation of neural precursor cell proliferationGO:2000177700.636
prostate glandular acinus developmentGO:0060525120.636
regulation of cellular component biogenesisGO:00440871810.636
positive regulation of thymocyte migrationGO:200041220.636
regulation of activation of jak2 kinase activityGO:001053410.635
regulation of filopodium assemblyGO:0051489130.635
t cell differentiationGO:00302171740.634
regulation of cell adhesionGO:00301551540.634
regulation of cytoplasmic transportGO:19036491120.633
positive regulation of smooth muscle cell migrationGO:001491140.632
positive regulation of t cell differentiationGO:0045582520.632
cellular response to inorganic substanceGO:0071241370.631
negative regulation of mesodermal cell fate specificationGO:004266230.630
regulation of skeletal muscle fiber developmentGO:0048742360.629
regulation of osteoclast differentiationGO:0045670360.627
respiratory tube developmentGO:00303231670.626
positive regulation of lipid kinase activityGO:0090218110.625
lung cell differentiationGO:0060479300.624
ventricular cardiac myofibril assemblyGO:005500530.622
negative regulation of endothelial cell differentiationGO:004560220.621
response to acid chemicalGO:00011011110.620

Ptpn11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
heart diseaseDOID:11400.988
disease of anatomical entityDOID:700.988
cardiovascular system diseaseDOID:128700.988
musculoskeletal system diseaseDOID:1700.803
cancerDOID:16200.648
Human
disease of cellular proliferationDOID:1456600.648
Human
organ system cancerDOID:005068600.648
Human