IMP: Integrative Multi-species Prediction

Mus musculus

11 known processes

Acot8

acyl-CoA thioesterase 8

(Aliases: PTE-2,Pte1)

Ensembl: ENSMUSG00000017307
Entrez: 170789
UniProtKB: P58137
UniProtKB: Q3U965

Process Predictions
Disease Predictions

Acot8 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cellular amino acid metabolic process	GO:0006520	103	0.082
spermatogenesis	GO:0007283	284	0.035
nitrogen compound transport	GO:0071705	271	0.035
regulation of cellular ketone metabolic process	GO:0010565	66	0.033
regulation of cellular amino acid metabolic process	GO:0006521	5	0.033
c4 dicarboxylate transport	GO:0015740	3	0.032
amine metabolic process	GO:0009308	45	0.031
germ cell development	GO:0007281	185	0.030
apoptotic signaling pathway	GO:0097190	306	0.030
transmembrane transport	GO:0055085	412	0.028
cation transport	GO:0006812	399	0.028
anion transport	GO:0006820	177	0.027
regulation of cellular amine metabolic process	GO:0033238	20	0.026
ion transmembrane transport	GO:0034220	361	0.026
carbohydrate derivative biosynthetic process	GO:1901137	183	0.026
compound eye development	GO:0048749	1	0.026
organic hydroxy compound metabolic process	GO:1901615	203	0.026
protein maturation	GO:0051604	176	0.023
carbohydrate metabolic process	GO:0005975	230	0.023
regulation of cell activation	GO:0050865	289	0.023
amide transport	GO:0042886	138	0.023
positive regulation of apoptotic process	GO:0043065	217	0.022
regulation of cell cycle	GO:0051726	281	0.022
regulation of lymphocyte activation	GO:0051249	240	0.022
succinate transport	GO:0015744	1	0.021
cellular amine metabolic process	GO:0044106	44	0.021
ribonucleoside metabolic process	GO:0009119	245	0.020
cellular macromolecule catabolic process	GO:0044265	206	0.020
cellular ketone metabolic process	GO:0042180	84	0.020
organic acid transport	GO:0015849	101	0.020
dephosphorylation	GO:0016311	129	0.020
inorganic ion transmembrane transport	GO:0098660	234	0.020
carboxylic acid transport	GO:0046942	100	0.019
regulation of transferase activity	GO:0051338	263	0.019
macromolecule catabolic process	GO:0009057	281	0.019
glycerolipid metabolic process	GO:0046486	122	0.019
regulation of hormone levels	GO:0010817	211	0.019
regulation of secretion by cell	GO:1903530	249	0.018
regulation of protein transport	GO:0051223	163	0.018
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.018
cellular lipid metabolic process	GO:0044255	323	0.018
male gamete generation	GO:0048232	285	0.017
positive regulation of cell death	GO:0010942	224	0.017
aromatic compound catabolic process	GO:0019439	286	0.017
glycosyl compound metabolic process	GO:1901657	246	0.017
organic cyclic compound catabolic process	GO:1901361	295	0.017
leukocyte differentiation	GO:0002521	342	0.016
microtubule based process	GO:0007017	236	0.016
positive regulation of cellular amine metabolic process	GO:0033240	5	0.016
regulation of kinase activity	GO:0043549	249	0.016
positive regulation of programmed cell death	GO:0043068	218	0.016
regulation of secretion	GO:0051046	274	0.015
positive regulation of transferase activity	GO:0051347	167	0.015
intracellular protein transport	GO:0006886	204	0.015
negative regulation of cellular component organization	GO:0051129	194	0.015
negative regulation of cell proliferation	GO:0008285	296	0.015
carbohydrate homeostasis	GO:0033500	128	0.015
regulation of membrane potential	GO:0042391	192	0.015
protein targeting	GO:0006605	143	0.015
positive regulation of protein phosphorylation	GO:0001934	242	0.015
regulation of organelle organization	GO:0033043	289	0.015
regulation of establishment of protein localization	GO:0070201	181	0.014
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.014
cytoplasmic transport	GO:0016482	234	0.014
nucleobase containing small molecule metabolic process	GO:0055086	352	0.014
protein localization to organelle	GO:0033365	185	0.014
heterocycle catabolic process	GO:0046700	280	0.014
cellular chemical homeostasis	GO:0055082	215	0.014
regulation of t cell activation	GO:0050863	170	0.014
inflammatory response	GO:0006954	244	0.014
regulation of proteolysis	GO:0030162	164	0.014
hormone secretion	GO:0046879	128	0.014
steroid metabolic process	GO:0008202	119	0.013
nucleoside metabolic process	GO:0009116	246	0.013
nucleotide metabolic process	GO:0009117	332	0.013
skeletal system development	GO:0001501	356	0.013
rna interference	GO:0016246	2	0.013
regulation of homeostatic process	GO:0032844	182	0.013
organelle localization	GO:0051640	179	0.013
exocytosis	GO:0006887	121	0.013
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.013
cellular homeostasis	GO:0019725	240	0.013
cellular response to cytokine stimulus	GO:0071345	189	0.013
organonitrogen compound biosynthetic process	GO:1901566	192	0.013
regulation of leukocyte differentiation	GO:1902105	159	0.013
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.013
negative regulation of cell cycle	GO:0045786	123	0.013
regulation of protein localization	GO:0032880	231	0.013
small gtpase mediated signal transduction	GO:0007264	97	0.013
organic anion transport	GO:0015711	137	0.013
protein processing	GO:0016485	163	0.013
purine ribonucleotide metabolic process	GO:0009150	290	0.013
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.013
ribose phosphate metabolic process	GO:0019693	291	0.012
regulation of cellular component biogenesis	GO:0044087	181	0.012
glucose metabolic process	GO:0006006	92	0.012
myeloid leukocyte differentiation	GO:0002573	119	0.012
protein catabolic process	GO:0030163	221	0.012
negative regulation of molecular function	GO:0044092	258	0.012
ribonucleotide metabolic process	GO:0009259	291	0.012
peptide transport	GO:0015833	133	0.012
protein localization to membrane	GO:0072657	108	0.012
cellular nitrogen compound catabolic process	GO:0044270	280	0.012
purine nucleotide metabolic process	GO:0006163	302	0.012
endocytosis	GO:0006897	168	0.011
oxidation reduction process	GO:0055114	342	0.011
regulation of apoptotic signaling pathway	GO:2001233	197	0.011
cellular response to lipid	GO:0071396	145	0.011
cellular ion homeostasis	GO:0006873	165	0.011
inorganic cation transmembrane transport	GO:0098662	207	0.011
cellular response to dna damage stimulus	GO:0006974	207	0.011
cellular carbohydrate metabolic process	GO:0044262	119	0.011
endomembrane system organization	GO:0010256	147	0.011
protein polymerization	GO:0051258	57	0.011
membrane organization	GO:0061024	245	0.011
positive regulation of homeostatic process	GO:0032846	64	0.011
inorganic anion transport	GO:0015698	43	0.011
meiotic cell cycle	GO:0051321	122	0.010
regulation of intracellular transport	GO:0032386	159	0.010
multi multicellular organism process	GO:0044706	109	0.010
nuclear transport	GO:0051169	139	0.010
regulation of protein kinase activity	GO:0045859	232	0.010
glucose homeostasis	GO:0042593	128	0.010
nucleoside phosphate catabolic process	GO:1901292	222	0.010
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.010
positive regulation of kinase activity	GO:0033674	155	0.010
acetylcholine transport	GO:0015870	2	0.010
nucleoside phosphate metabolic process	GO:0006753	338	0.010
regulation of intracellular protein transport	GO:0033157	82	0.010

Acot8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.021
immune system disease	DOID:2914	0.021
hematopoietic system disease	DOID:74	0.014
nervous system disease	DOID:863	0.013
inherited metabolic disorder	DOID:655	0.010
disease of metabolism	DOID:0014667	0.010

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