IMP: Integrative Multi-species Prediction

Mus musculus

39 known processes

Epha1

Eph receptor A1

(Aliases: AL033318,Esk,5730453L17Rik,Eph)

Entrez: 13835
Ensembl: ENSMUSG00000029859
UniProtKB: Q60750

Process Predictions
Disease Predictions

Epha1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
positive regulation of gtp catabolic process	GO:0033126	85	0.676	Human
gtp catabolic process	GO:0006184	143	0.617	Human Mouse
ras protein signal transduction	GO:0007265	77	0.613
purine ribonucleoside metabolic process	GO:0046128	241	0.589	Human Mouse
nucleoside triphosphate metabolic process	GO:0009141	230	0.583	Human Mouse
organic cyclic compound catabolic process	GO:1901361	295	0.577	Human Mouse
ribonucleoside metabolic process	GO:0009119	245	0.563	Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.554	Human Mouse
organonitrogen compound catabolic process	GO:1901565	264	0.544	Human Mouse
nucleotide catabolic process	GO:0009166	217	0.537	Human Mouse
ribonucleotide catabolic process	GO:0009261	208	0.536	Human Mouse
purine ribonucleotide catabolic process	GO:0009154	208	0.519	Human Mouse
nucleoside triphosphate catabolic process	GO:0009143	205	0.501	Human Mouse
heterocycle catabolic process	GO:0046700	280	0.491	Human Mouse
guanosine containing compound metabolic process	GO:1901068	144	0.487	Human Mouse
guanosine containing compound catabolic process	GO:1901069	144	0.482	Human Mouse
purine nucleoside metabolic process	GO:0042278	241	0.473	Human Mouse
purine ribonucleotide metabolic process	GO:0009150	290	0.472	Human Mouse
nucleoside phosphate catabolic process	GO:1901292	222	0.467	Human Mouse
aromatic compound catabolic process	GO:0019439	286	0.460	Human Mouse
cellular amine metabolic process	GO:0044106	44	0.458
positive regulation of protein phosphorylation	GO:0001934	242	0.447	Mouse
carbohydrate derivative catabolic process	GO:1901136	231	0.421	Human Mouse
cellular nitrogen compound catabolic process	GO:0044270	280	0.415	Human Mouse
purine nucleoside catabolic process	GO:0006152	205	0.413	Human Mouse
nephric duct formation	GO:0072179	4	0.411
regulation of purine nucleotide catabolic process	GO:0033121	122	0.399	Human Mouse
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.392	Human Mouse
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.385
purine ribonucleoside catabolic process	GO:0046130	205	0.378	Human Mouse
regulation of purine nucleotide metabolic process	GO:1900542	169	0.377	Human Mouse
wnt signaling pathway	GO:0016055	188	0.375
ear development	GO:0043583	200	0.373	Mouse
purine containing compound metabolic process	GO:0072521	311	0.373	Human Mouse
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.367	Human Mouse
organophosphate catabolic process	GO:0046434	232	0.364	Human Mouse
positive regulation of cellular catabolic process	GO:0031331	148	0.353	Human
morphogenesis of an epithelial fold	GO:0060571	28	0.350
ribose phosphate metabolic process	GO:0019693	291	0.345	Human Mouse
ossification	GO:0001503	216	0.345	Mouse
regulation of nucleoside metabolic process	GO:0009118	130	0.339	Human Mouse
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.337
canonical wnt signaling pathway	GO:0060070	130	0.331
nucleoside phosphate metabolic process	GO:0006753	338	0.330	Human Mouse
regulation of neuron differentiation	GO:0045664	281	0.328	Mouse
purine nucleotide metabolic process	GO:0006163	302	0.326	Human Mouse
clara cell differentiation	GO:0060486	4	0.323
gland development	GO:0048732	330	0.321	Mouse
male gamete generation	GO:0048232	285	0.316
negative regulation of cell proliferation	GO:0008285	296	0.315
regulation of protein kinase activity	GO:0045859	232	0.314	Human Mouse
positive regulation of nucleotide catabolic process	GO:0030813	88	0.306	Human
regulation of cellular amine metabolic process	GO:0033238	20	0.305
nucleobase containing small molecule metabolic process	GO:0055086	352	0.294	Human Mouse
regulation of cellular ketone metabolic process	GO:0010565	66	0.289
positive regulation of nervous system development	GO:0051962	221	0.280	Mouse
regulation of ossification	GO:0030278	112	0.279
cell adhesion	GO:0007155	329	0.277	Human Mouse
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.271	Human Mouse
mapk cascade	GO:0000165	281	0.265	Mouse
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.263	Human Mouse
positive regulation of hydrolase activity	GO:0051345	148	0.261	Human
regulation of organ morphogenesis	GO:2000027	144	0.261
epithelial tube morphogenesis	GO:0060562	303	0.250	Mouse
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.249	Mouse
regulation of nucleotide catabolic process	GO:0030811	122	0.245	Human Mouse
regionalization	GO:0003002	337	0.244
regulation of hydrolase activity	GO:0051336	246	0.244	Human Mouse
regulation of cytokine production	GO:0001817	266	0.242
positive regulation of apoptotic process	GO:0043065	217	0.240	Mouse
leukocyte differentiation	GO:0002521	342	0.240	Mouse
hair follicle development	GO:0001942	85	0.240
regulation of stem cell differentiation	GO:2000736	50	0.237	Mouse
positive regulation of ras gtpase activity	GO:0032320	65	0.231	Human
fat cell differentiation	GO:0045444	160	0.229
endocrine system development	GO:0035270	98	0.229
regulation of transferase activity	GO:0051338	263	0.227	Human Mouse
cell fate commitment	GO:0045165	210	0.227
synaptic transmission	GO:0007268	329	0.226	Mouse
negative regulation of synapse assembly	GO:0051964	3	0.224	Mouse
establishment of organelle localization	GO:0051656	122	0.222
fibroblast growth factor receptor signaling pathway	GO:0008543	46	0.220
glycosyl compound catabolic process	GO:1901658	206	0.218	Human Mouse
respiratory system development	GO:0060541	190	0.211
regulation of cellular catabolic process	GO:0031329	242	0.211	Human Mouse
nucleoside catabolic process	GO:0009164	206	0.210	Human Mouse
circulatory system process	GO:0003013	197	0.209
wound healing	GO:0042060	157	0.205
mesonephric duct formation	GO:0072181	2	0.201
regulation of neuron projection development	GO:0010975	169	0.200	Mouse
nucleotide metabolic process	GO:0009117	332	0.198	Human Mouse
positive regulation of gtpase activity	GO:0043547	85	0.197	Human
lung development	GO:0030324	164	0.196
negative regulation of hormone biosynthetic process	GO:0032353	4	0.193
cellular ketone metabolic process	GO:0042180	84	0.187
regulation of body fluid levels	GO:0050878	162	0.187	Mouse
regulation of mapk cascade	GO:0043408	248	0.184	Mouse
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.181	Human
ribonucleoside catabolic process	GO:0042454	206	0.181	Human Mouse
establishment of tissue polarity	GO:0007164	28	0.181
spermatogenesis	GO:0007283	284	0.181
embryonic organ morphogenesis	GO:0048562	276	0.180	Mouse
t cell activation	GO:0042110	289	0.179
lymphocyte activation involved in immune response	GO:0002285	93	0.179
sensory organ morphogenesis	GO:0090596	242	0.178	Mouse
embryonic epithelial tube formation	GO:0001838	130	0.177
positive regulation of cell development	GO:0010720	237	0.175	Mouse
lipid biosynthetic process	GO:0008610	179	0.169
positive regulation of nucleotide metabolic process	GO:0045981	114	0.167	Human
regulation of cell size	GO:0008361	72	0.165
regulation of vasculature development	GO:1901342	88	0.162	Human Mouse
regulation of ras protein signal transduction	GO:0046578	114	0.159	Human Mouse
mesonephric duct morphogenesis	GO:0072180	4	0.157
inner ear morphogenesis	GO:0042472	101	0.155	Mouse
biomineral tissue development	GO:0031214	64	0.155
ribonucleotide metabolic process	GO:0009259	291	0.155	Human Mouse
negative regulation of cell development	GO:0010721	169	0.154	Mouse
regulation of protein serine threonine kinase activity	GO:0071900	157	0.154	Mouse
cell cell junction organization	GO:0045216	72	0.153
protein localization to plasma membrane	GO:0072659	57	0.152
epithelial tube formation	GO:0072175	130	0.151
stem cell development	GO:0048864	219	0.151	Mouse
t cell differentiation	GO:0030217	174	0.149
skin development	GO:0043588	220	0.149
positive regulation of epithelial cell proliferation involved in lung morphogenesis	GO:0060501	3	0.148
blood vessel morphogenesis	GO:0048514	285	0.148	Human Mouse
camera type eye development	GO:0043010	266	0.148	Mouse
gtp metabolic process	GO:0046039	144	0.147	Human Mouse
axonogenesis	GO:0007409	274	0.147	Mouse Worm
myoblast differentiation involved in skeletal muscle regeneration	GO:0014835	3	0.147
anatomical structure maturation	GO:0071695	49	0.147
somatic stem cell maintenance	GO:0035019	47	0.147
tertiary branching involved in mammary gland duct morphogenesis	GO:0060748	3	0.146
positive regulation of protein kinase activity	GO:0045860	144	0.146	Mouse
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.144
regulation of cell cycle process	GO:0010564	160	0.144
regulation of cardiac muscle cell proliferation	GO:0060043	23	0.142
ear morphogenesis	GO:0042471	118	0.141	Mouse
regulation of organelle organization	GO:0033043	289	0.140
muscle cell proliferation	GO:0033002	52	0.140
regulation of cell activation	GO:0050865	289	0.140
single organismal cell cell adhesion	GO:0016337	131	0.140	Mouse
kidney development	GO:0001822	213	0.139
rho protein signal transduction	GO:0007266	32	0.136
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	40	0.135
purine nucleotide catabolic process	GO:0006195	211	0.134	Human Mouse
regulation of cellular amino acid metabolic process	GO:0006521	5	0.133
non canonical wnt signaling pathway via jnk cascade	GO:0038031	3	0.133
cellular response to growth factor stimulus	GO:0071363	197	0.131
planar cell polarity pathway involved in outflow tract morphogenesis	GO:0061347	2	0.131
type b pancreatic cell differentiation	GO:0003309	13	0.130
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.127	Human Mouse
bmp signaling pathway	GO:0030509	93	0.124
regulation of map kinase activity	GO:0043405	120	0.123	Mouse
regulation of cardiac muscle tissue development	GO:0055024	31	0.123
central nervous system morphogenesis	GO:0021551	2	0.122
placenta development	GO:0001890	140	0.122
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	GO:0061350	2	0.120
regulation of lymphocyte activation	GO:0051249	240	0.119
regulation of secretion	GO:0051046	274	0.119	Mouse
glycosyl compound metabolic process	GO:1901657	246	0.117	Human Mouse
appendage development	GO:0048736	166	0.116
spemann organizer formation at the anterior end of the primitive streak	GO:0060064	1	0.116
organelle localization	GO:0051640	179	0.115
embryonic digestive tract development	GO:0048566	27	0.114
nucleoside metabolic process	GO:0009116	246	0.113	Human Mouse
positive regulation of cellular amine metabolic process	GO:0033240	5	0.113
positive regulation of cell death	GO:0010942	224	0.113	Mouse
regulation of ras gtpase activity	GO:0032318	88	0.109	Human Mouse
regulation of nucleotide metabolic process	GO:0006140	169	0.107	Human Mouse
purine containing compound catabolic process	GO:0072523	213	0.106	Human Mouse
regulation of gtp catabolic process	GO:0033124	113	0.105	Human Mouse
planar cell polarity pathway involved in ventricular septum morphogenesis	GO:0061348	2	0.105
muscle cell differentiation	GO:0042692	261	0.105
response to growth factor	GO:0070848	198	0.103
morphogenesis of a polarized epithelium	GO:0001738	37	0.103
organelle fission	GO:0048285	170	0.102
hindbrain formation	GO:0021576	1	0.101
protein localization to membrane	GO:0072657	108	0.101
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	3	0.100
amine metabolic process	GO:0009308	45	0.100
epidermis development	GO:0008544	187	0.099
striated muscle cell proliferation	GO:0014855	39	0.099
embryonic placenta development	GO:0001892	98	0.099
lens development in camera type eye	GO:0002088	62	0.099	Mouse
stem cell proliferation	GO:0072089	117	0.098
planar cell polarity pathway involved in pericardium morphogenesis	GO:0061354	2	0.098
cardioblast migration to the midline involved in heart field formation	GO:0060975	1	0.098
inner medullary collecting duct development	GO:0072061	2	0.097
negative regulation of cell cycle	GO:0045786	123	0.097
non canonical wnt signaling pathway involved in heart development	GO:0061341	3	0.097
hair follicle morphogenesis	GO:0031069	29	0.096
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation	GO:2000079	1	0.095
hormone secretion	GO:0046879	128	0.094	Mouse
cellular lipid metabolic process	GO:0044255	323	0.094	Mouse
pituitary gland development	GO:0021983	38	0.094
organ growth	GO:0035265	117	0.094
heart contraction	GO:0060047	93	0.094
cardiac muscle tissue growth	GO:0055017	37	0.093
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.092
regulation of wnt signaling pathway	GO:0030111	123	0.092
hair cycle	GO:0042633	90	0.092
neuron projection guidance	GO:0097485	141	0.092	Mouse Worm
midbrain hindbrain boundary maturation	GO:0021732	1	0.092
embryonic digestive tract morphogenesis	GO:0048557	17	0.091
organ induction	GO:0001759	21	0.091
developmental growth involved in morphogenesis	GO:0060560	138	0.091
renal outer medulla development	GO:0072054	2	0.091
heart process	GO:0003015	94	0.090
regulation of canonical wnt signaling pathway	GO:0060828	82	0.090
negative regulation of cellular component organization	GO:0051129	194	0.088	Mouse
heart morphogenesis	GO:0003007	178	0.088	Mouse
lung induction	GO:0060492	3	0.088
somatotropin secreting cell differentiation	GO:0060126	4	0.088
regulation of kinase activity	GO:0043549	249	0.087	Human Mouse
canonical wnt signaling pathway involved in regulation of cell proliferation	GO:0044340	3	0.087
renal vesicle induction	GO:0072034	3	0.087
central nervous system neuron development	GO:0021954	67	0.086	Mouse
negative regulation of phosphate metabolic process	GO:0045936	184	0.086	Human
stem cell maintenance	GO:0019827	130	0.085
regulation of testosterone biosynthetic process	GO:2000224	2	0.085
positive regulation of nucleoside metabolic process	GO:0045979	91	0.085	Human
apoptotic signaling pathway	GO:0097190	306	0.085
mesenchyme development	GO:0060485	152	0.085	Mouse
stem cell differentiation	GO:0048863	268	0.085	Mouse
male sex differentiation	GO:0046661	109	0.085
regulation of cell cell adhesion mediated by cadherin	GO:2000047	2	0.084
regulation of muscle tissue development	GO:1901861	97	0.084
non canonical wnt signaling pathway	GO:0035567	33	0.083
regulation of hormone levels	GO:0010817	211	0.083	Mouse
homotypic cell cell adhesion	GO:0034109	28	0.083
blood circulation	GO:0008015	195	0.083
angiogenesis	GO:0001525	201	0.082	Human Mouse
positive regulation of rho gtpase activity	GO:0032321	41	0.082	Human
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.082
salivary gland morphogenesis	GO:0007435	33	0.081
carbohydrate metabolic process	GO:0005975	230	0.081
digestive tract morphogenesis	GO:0048546	147	0.081	Mouse
positive regulation of anagen	GO:0051885	1	0.081
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	GO:0014834	3	0.081
tube formation	GO:0035148	140	0.081
cell growth	GO:0016049	130	0.081
stress activated mapk cascade	GO:0051403	80	0.080	Mouse
dna templated transcriptional preinitiation complex assembly	GO:0070897	4	0.080
peptide hormone secretion	GO:0030072	109	0.080	Mouse
peptidyl tyrosine phosphorylation	GO:0018108	143	0.080	Human Mouse Worm
striated muscle tissue development	GO:0014706	293	0.080
developmental induction	GO:0031128	34	0.079
negative regulation of cellular amine metabolic process	GO:0033239	1	0.078
regulation of cardiac muscle tissue growth	GO:0055021	26	0.078
cd4 positive alpha beta t cell activation	GO:0035710	45	0.078
developmental maturation	GO:0021700	193	0.078	Mouse Worm
morphogenesis of embryonic epithelium	GO:0016331	159	0.078	Worm
renal system development	GO:0072001	225	0.078
actin cytoskeleton organization	GO:0030036	220	0.078
monocarboxylic acid metabolic process	GO:0032787	191	0.078
cardiac muscle tissue development	GO:0048738	130	0.078
ubiquitin dependent smad protein catabolic process	GO:0030579	2	0.077
wnt signaling pathway involved in forebrain neuroblast division	GO:0021874	2	0.077
molting cycle	GO:0042303	90	0.077
negative regulation of cell morphogenesis involved in differentiation	GO:0010771	48	0.077	Mouse
labyrinthine layer blood vessel development	GO:0060716	21	0.076
cell type specific apoptotic process	GO:0097285	268	0.076	Mouse
microtubule cytoskeleton organization	GO:0000226	157	0.075
polarity specification of proximal distal axis	GO:0010085	2	0.075
single organism cell adhesion	GO:0098602	156	0.075	Human Mouse
regulation of osteoblast differentiation	GO:0045667	67	0.075
cd4 positive alpha beta t cell differentiation	GO:0043367	41	0.075
central nervous system vasculogenesis	GO:0022009	3	0.075
bone mineralization	GO:0030282	54	0.075
regulation of neuron death	GO:1901214	134	0.074	Mouse
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.074
alcohol metabolic process	GO:0006066	116	0.074
positive regulation of neuron differentiation	GO:0045666	141	0.074
mitotic cell cycle	GO:0000278	195	0.073
regulation of morphogenesis of a branching structure	GO:0060688	53	0.073
blood coagulation	GO:0007596	76	0.073
positive regulation of megakaryocyte differentiation	GO:0045654	4	0.072
regulation of anatomical structure size	GO:0090066	178	0.072
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.072	Human Mouse
establishment of planar polarity	GO:0001736	28	0.072
protein lipid complex subunit organization	GO:0071825	12	0.072
asymmetric neuroblast division	GO:0055059	1	0.072
positive regulation of interleukin 8 production	GO:0032757	2	0.072
positive regulation of cardiac muscle tissue growth	GO:0055023	15	0.072
small gtpase mediated signal transduction	GO:0007264	97	0.072
establishment of organ orientation	GO:0048561	1	0.072
central nervous system neuron differentiation	GO:0021953	162	0.072	Mouse
maintenance of cell number	GO:0098727	3	0.071
nephron epithelium morphogenesis	GO:0072088	68	0.071
negative regulation of canonical wnt signaling pathway	GO:0090090	51	0.071
regulation of peptide hormone secretion	GO:0090276	75	0.070	Mouse
hematopoietic progenitor cell differentiation	GO:0002244	143	0.070
planar cell polarity pathway involved in cardiac right atrium morphogenesis	GO:0061349	2	0.070
appendage morphogenesis	GO:0035107	149	0.070
regulation of lymphocyte proliferation	GO:0050670	117	0.070
leukocyte proliferation	GO:0070661	172	0.070
regulation of cell projection organization	GO:0031344	206	0.070	Mouse
macromolecule catabolic process	GO:0009057	281	0.069
sodium ion transport	GO:0006814	73	0.069
cell cell adhesion	GO:0098609	41	0.069
foregut regionalization	GO:0060423	3	0.069
regulation of mitotic cell cycle	GO:0007346	126	0.069
positive regulation of protein modification process	GO:0031401	299	0.068	Mouse
prostate gland epithelium morphogenesis	GO:0060740	31	0.068
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation	GO:2000081	1	0.067
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.067
cytokine production	GO:0001816	319	0.067
regulation of reproductive process	GO:2000241	66	0.067	Worm
axis elongation involved in somitogenesis	GO:0090245	4	0.066
cellular amino acid metabolic process	GO:0006520	103	0.066
negative regulation of prostatic bud formation	GO:0060686	4	0.066
alpha beta t cell differentiation	GO:0046632	69	0.066
gas homeostasis	GO:0033483	3	0.065
transforming growth factor beta2 production	GO:0032906	2	0.065
non canonical wnt signaling pathway via mapk cascade	GO:0038030	3	0.065
lateral sprouting involved in mammary gland duct morphogenesis	GO:0060599	2	0.065
regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045898	2	0.065
wnt signaling pathway planar cell polarity pathway	GO:0060071	27	0.065
organic hydroxy compound metabolic process	GO:1901615	203	0.065	Fly
leukocyte activation involved in immune response	GO:0002366	126	0.065
steroid metabolic process	GO:0008202	119	0.065
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.064
regulation of cardioblast differentiation	GO:0051890	3	0.064
regulation of cellular component size	GO:0032535	121	0.064
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation	GO:0044343	1	0.064
morphogenesis of a branching structure	GO:0001763	203	0.064	Mouse
salivary gland development	GO:0007431	37	0.064
regulation of stem cell proliferation	GO:0072091	78	0.064
urogenital system development	GO:0001655	261	0.064	Mouse
trachea cartilage morphogenesis	GO:0060535	4	0.063
positive regulation of cell cell adhesion mediated by cadherin	GO:2000049	2	0.063
nephron tubule formation	GO:0072079	20	0.063
positive regulation of cytokine production	GO:0001819	174	0.063
cell junction organization	GO:0034330	77	0.063
inorganic ion transmembrane transport	GO:0098660	234	0.062
negative regulation of neuron differentiation	GO:0045665	101	0.062	Mouse
learning or memory	GO:0007611	148	0.062	Mouse
planar cell polarity pathway involved in heart morphogenesis	GO:0061346	3	0.062
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.061
regulation of cell motility	GO:2000145	236	0.061	Human Mouse
cerebellum formation	GO:0021588	1	0.061
chemotaxis	GO:0006935	247	0.061	Mouse Worm
positive regulation of transforming growth factor beta2 production	GO:0032915	2	0.061
prostate gland morphogenesis	GO:0060512	32	0.061
peptidyl tyrosine modification	GO:0018212	145	0.060	Human Mouse Worm
specification of organ identity	GO:0010092	30	0.060
peptidyl amino acid modification	GO:0018193	336	0.060	Human Mouse Worm
prostate gland development	GO:0030850	48	0.060
cation transport	GO:0006812	399	0.060
cation homeostasis	GO:0055080	212	0.060	Mouse
septum primum development	GO:0003284	4	0.059
positive regulation of interleukin 8 secretion	GO:2000484	1	0.059
regulation of cell division	GO:0051302	76	0.059
development of primary male sexual characteristics	GO:0046546	88	0.059
establishment of planar polarity involved in nephron morphogenesis	GO:0072046	1	0.059
hypophysis morphogenesis	GO:0048850	3	0.059
cellular response to fibroblast growth factor stimulus	GO:0044344	47	0.059
multicellular organismal homeostasis	GO:0048871	164	0.059
negative regulation of hormone metabolic process	GO:0032351	4	0.058
negative regulation of growth	GO:0045926	99	0.058
alcohol biosynthetic process	GO:0046165	43	0.058
type ii pneumocyte differentiation	GO:0060510	7	0.058
cardiac chamber morphogenesis	GO:0003206	93	0.058
small molecule biosynthetic process	GO:0044283	132	0.058
cellular response to follicle stimulating hormone stimulus	GO:0071372	1	0.058
positive regulation of interleukin 13 production	GO:0032736	4	0.058
amide transport	GO:0042886	138	0.058	Mouse
negative regulation of wnt signaling pathway	GO:0030178	73	0.058
lymphocyte proliferation	GO:0046651	164	0.057
regulation of transforming growth factor beta2 production	GO:0032909	2	0.057
leukocyte migration	GO:0050900	124	0.057
regulation of lymphocyte differentiation	GO:0045619	107	0.057
stem cell division	GO:0017145	30	0.057
cop9 signalosome assembly	GO:0010387	2	0.057
outer medullary collecting duct development	GO:0072060	1	0.057
mammary gland duct morphogenesis	GO:0060603	38	0.057	Mouse
response to retinoic acid	GO:0032526	56	0.056
adult behavior	GO:0030534	135	0.056	Mouse
jnk cascade	GO:0007254	72	0.055	Mouse
pancreas development	GO:0031016	57	0.055
phospholipid metabolic process	GO:0006644	87	0.055	Mouse
response to fibroblast growth factor	GO:0071774	47	0.055
lung epithelium development	GO:0060428	37	0.055
myeloid leukocyte differentiation	GO:0002573	119	0.055	Mouse
regulation of cell growth	GO:0001558	91	0.055
vesicle localization	GO:0051648	86	0.054
endodermal cell fate determination	GO:0007493	2	0.054
cartilage development	GO:0051216	140	0.054
negative regulation of macrophage differentiation	GO:0045650	4	0.054
forebrain development	GO:0030900	302	0.054	Mouse
germ cell development	GO:0007281	185	0.054	Worm
fat soluble vitamin biosynthetic process	GO:0042362	4	0.054
spemann organizer formation	GO:0060061	2	0.053
skin morphogenesis	GO:0043589	38	0.053
diencephalon development	GO:0021536	63	0.053
male genitalia morphogenesis	GO:0048808	4	0.053
positive regulation of programmed cell death	GO:0043068	218	0.052	Mouse
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.052
regulation of establishment of planar polarity	GO:0090175	28	0.052
cardioblast migration	GO:0003260	1	0.052
negative regulation of testosterone biosynthetic process	GO:2000225	1	0.052
regulation of anagen	GO:0051884	1	0.052
negative regulation of mesenchymal cell proliferation	GO:0072201	3	0.052
developmental cell growth	GO:0048588	84	0.052
positive regulation of mapk cascade	GO:0043410	170	0.051	Mouse
mammary gland epithelium development	GO:0061180	65	0.051	Mouse
peptide secretion	GO:0002790	114	0.051	Mouse
positive regulation of muscle tissue development	GO:1901863	32	0.051
female genitalia morphogenesis	GO:0048807	3	0.051
regulation of neuron apoptotic process	GO:0043523	122	0.051	Mouse
multicellular organismal signaling	GO:0035637	91	0.051
branch elongation involved in salivary gland morphogenesis	GO:0060667	2	0.051
epithelial cell morphogenesis	GO:0003382	41	0.051
regulation of ion transport	GO:0043269	215	0.050
positive regulation of heart growth	GO:0060421	18	0.050
embryonic appendage morphogenesis	GO:0035113	126	0.050
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.050	Human
limb morphogenesis	GO:0035108	149	0.050
lipid transport	GO:0006869	98	0.050
fibroblast growth factor production	GO:0090269	4	0.050
heart growth	GO:0060419	45	0.050
hemostasis	GO:0007599	78	0.050
midbrain hindbrain boundary maturation during brain development	GO:0022004	1	0.049
endocytosis	GO:0006897	168	0.049
regulation of hormone secretion	GO:0046883	88	0.049	Mouse
lung field specification	GO:0060424	3	0.049
epithelial cell proliferation	GO:0050673	174	0.049	Mouse
negative regulation of phosphorylation	GO:0042326	166	0.049	Human
regulation of fibroblast growth factor production	GO:0090270	4	0.049
establishment of vesicle localization	GO:0051650	81	0.048
nuclear division	GO:0000280	158	0.048
cardiac muscle cell proliferation	GO:0060038	31	0.048
odontogenesis of dentin containing tooth	GO:0042475	66	0.048
membrane organization	GO:0061024	245	0.048
negative regulation of nervous system development	GO:0051961	156	0.048	Mouse
regulation of mesenchymal cell proliferation	GO:0010464	37	0.048
microtubule based process	GO:0007017	236	0.047
regulation of neural precursor cell proliferation	GO:2000177	70	0.047
muscle tissue development	GO:0060537	308	0.047
regulation of fat cell differentiation	GO:0045598	81	0.047
positive regulation of cell activation	GO:0050867	158	0.047
cardiac right atrium morphogenesis	GO:0003213	3	0.047
negative regulation of ossification	GO:0030279	49	0.047
connective tissue development	GO:0061448	179	0.047
myeloid cell differentiation	GO:0030099	233	0.047	Mouse
regulation of extent of cell growth	GO:0061387	52	0.047
immune response regulating cell surface receptor signaling pathway	GO:0002768	80	0.046
neuron apoptotic process	GO:0051402	142	0.046	Mouse
respiratory tube development	GO:0030323	167	0.046
tissue migration	GO:0090130	68	0.046	Mouse
regulation of heart growth	GO:0060420	31	0.046
positive regulation of map kinase activity	GO:0043406	84	0.046	Mouse
regulation of organ growth	GO:0046620	61	0.046
cardiac cell fate determination	GO:0060913	2	0.046
metanephros development	GO:0001656	79	0.046
response to acid chemical	GO:0001101	111	0.046
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.045	Mouse
positive regulation of striated muscle tissue development	GO:0045844	31	0.045
trabecula morphogenesis	GO:0061383	40	0.045
regulation of t cell activation	GO:0050863	170	0.045
testosterone biosynthetic process	GO:0061370	2	0.045
oviduct development	GO:0060066	3	0.045
oxygen homeostasis	GO:0032364	2	0.045
establishment of protein localization to membrane	GO:0090150	54	0.045
fatty acid metabolic process	GO:0006631	121	0.045
digestive system development	GO:0055123	200	0.044	Mouse
organic hydroxy compound biosynthetic process	GO:1901617	77	0.044
lymphocyte differentiation	GO:0030098	242	0.044
spinal cord development	GO:0021510	81	0.044
skeletal system development	GO:0001501	356	0.044	Mouse
cellular response to biotic stimulus	GO:0071216	92	0.044
regulation of biomineral tissue development	GO:0070167	33	0.043
uterus morphogenesis	GO:0061038	2	0.043
kidney morphogenesis	GO:0060993	83	0.043
regulation of system process	GO:0044057	200	0.043
morphogenesis of an epithelial bud	GO:0060572	18	0.043
nuclear transport	GO:0051169	139	0.043
positive regulation of cardioblast differentiation	GO:0051891	3	0.043
b cell activation involved in immune response	GO:0002312	50	0.043
lipid homeostasis	GO:0055088	63	0.043
axis elongation	GO:0003401	30	0.042
negative regulation of cell growth	GO:0030308	44	0.042
regulation of homeostatic process	GO:0032844	182	0.042	Mouse
cardiac ventricle development	GO:0003231	83	0.042
dna metabolic process	GO:0006259	303	0.042
negative regulation of axon guidance	GO:1902668	8	0.042
neural tube formation	GO:0001841	108	0.042
chondrocyte differentiation	GO:0002062	72	0.042
negative regulation of cell projection organization	GO:0031345	56	0.041	Mouse
regulation of epithelial cell proliferation	GO:0050678	141	0.041
mesonephros development	GO:0001823	97	0.041
epithelial cell development	GO:0002064	159	0.041	Mouse
determination of left right symmetry	GO:0007368	80	0.041

Epha1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.181
	musculoskeletal system disease	DOID:17	0	0.181

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