Mus musculus

108 known processes

Gclm

glutamate-cysteine ligase, modifier subunit

(Aliases: Glclr,AI649393)

Gclm biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
glutathione metabolic processGO:0006749160.996
cellular amino acid biosynthetic processGO:0008652220.991
l ascorbic acid metabolic processGO:001985240.991
serine family amino acid metabolic processGO:000906970.991
glutathione biosynthetic processGO:000675040.953
cellular modified amino acid biosynthetic processGO:0042398120.950
peptide metabolic processGO:0006518460.920
regulation of membrane depolarizationGO:0003254110.917
cellular modified amino acid metabolic processGO:0006575630.875
sulfur compound metabolic processGO:00067901000.841
cysteine metabolic processGO:000653430.827
organic acid biosynthetic processGO:0016053860.793
cellular amide metabolic processGO:0043603580.775
water soluble vitamin metabolic processGO:0006767100.712
cellular amino acid metabolic processGO:00065201030.698
regulation of mitochondrial depolarizationGO:005190050.686
sulfur amino acid metabolic processGO:000009690.665
apoptotic mitochondrial changesGO:0008637480.644
mitochondrion organizationGO:00070051340.583
response to oxidative stressGO:00069791230.578
membrane depolarizationGO:0051899640.545
regulation of mitochondrial membrane potentialGO:0051881170.515
small molecule biosynthetic processGO:00442831320.493
protein modification by small protein conjugationGO:00324461870.461
peptide biosynthetic processGO:0043043110.451
regulation of membrane potentialGO:00423911920.446
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.418
regulation of apoptotic signaling pathwayGO:20012331970.413
organonitrogen compound biosynthetic processGO:19015661920.394
regulation of ion homeostasisGO:2000021640.393
extrinsic apoptotic signaling pathwayGO:00971911260.357
negative regulation of apoptotic signaling pathwayGO:20012341040.345
response to arsenic containing substanceGO:004668550.335
cellular protein catabolic processGO:00442571550.333
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.319
regulation of blood vessel sizeGO:0050880560.315
Human
modification dependent macromolecule catabolic processGO:00436321330.309
proteasomal protein catabolic processGO:0010498980.305
proteolysis involved in cellular protein catabolic processGO:00516031470.304
vascular process in circulatory systemGO:0003018620.302
Human
cellular macromolecule catabolic processGO:00442652060.302
circulatory system processGO:00030131970.301
Human
modification dependent protein catabolic processGO:00199411330.298
ubiquitin dependent protein catabolic processGO:00065111290.295
positive regulation of cellular catabolic processGO:00313311480.291
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.289
protein modification by small protein conjugation or removalGO:00706472070.288
regulation of cellular protein catabolic processGO:1903362610.285
protein ubiquitinationGO:00165671710.284
macromolecule catabolic processGO:00090572810.280
carbohydrate metabolic processGO:00059752300.278
regulation of homeostatic processGO:00328441820.278
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.272
negative regulation of protein metabolic processGO:00512482820.258
monosaccharide metabolic processGO:00059961060.251
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.245
regulation of proteolysisGO:00301621640.230
regulation of anatomical structure sizeGO:00900661780.223
Human
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.220
regulation of tube sizeGO:0035150570.219
Human
regulation of cellular catabolic processGO:00313292420.205
negative regulation of cellular protein metabolic processGO:00322692470.203
positive regulation of cellular protein catabolic processGO:1903364340.193
negative regulation of protein modification processGO:00314001630.192
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.174
protein catabolic processGO:00301632210.171
positive regulation of proteolysisGO:0045862850.167
regulation of proteasomal protein catabolic processGO:0061136460.126
cellular lipid metabolic processGO:00442553230.106
response to heatGO:0009408270.105
regulation of protein catabolic processGO:00421761080.103
positive regulation of protein catabolic processGO:0045732600.099
response to temperature stimulusGO:0009266550.082
ion transmembrane transportGO:00342203610.076
cellular amine metabolic processGO:0044106440.067
cellular ketone metabolic processGO:0042180840.066
response to xenobiotic stimulusGO:0009410130.066
regulation of protein ubiquitinationGO:0031396520.064
regulation of protein modification by small protein conjugation or removalGO:1903320570.060
oxidation reduction processGO:00551143420.058
positive regulation of cellular amino acid metabolic processGO:004576430.058
positive regulation of cellular amine metabolic processGO:003324050.056
regulation of cellular amino acid metabolic processGO:000652150.056
response to organonitrogen compoundGO:00102432460.052
regulation of cellular amine metabolic processGO:0033238200.051
transmembrane transportGO:00550854120.050
cellular homeostasisGO:00197252400.049
nitrogen compound transportGO:00717052710.049
regulation of cellular ketone metabolic processGO:0010565660.048
amine metabolic processGO:0009308450.048
cation transmembrane transportGO:00986552660.044
lipid biosynthetic processGO:00086101790.043
negative regulation of protein ubiquitinationGO:0031397190.042
anion transportGO:00068201770.042
nucleobase containing small molecule metabolic processGO:00550863520.041
cation transportGO:00068123990.040
reactive oxygen species metabolic processGO:0072593840.038
nucleoside phosphate metabolic processGO:00067533380.038
peptidyl amino acid modificationGO:00181933360.037
response to organic cyclic compoundGO:00140701980.037
inorganic ion transmembrane transportGO:00986602340.036
apoptotic signaling pathwayGO:00971903060.036
spermatogenesisGO:00072832840.036
myeloid cell differentiationGO:00300992330.036
purine ribonucleotide metabolic processGO:00091502900.035
organic cyclic compound catabolic processGO:19013612950.035
metal ion homeostasisGO:00550651890.035
carbohydrate derivative biosynthetic processGO:19011371830.035
ribonucleoside metabolic processGO:00091192450.034
purine nucleotide metabolic processGO:00061633020.034
ribonucleoside triphosphate metabolic processGO:00091992200.034
chromatin organizationGO:00063252060.032
male gamete generationGO:00482322850.032
cation homeostasisGO:00550802120.032
response to extracellular stimulusGO:00099911270.032
response to inorganic substanceGO:0010035960.032
inorganic cation transmembrane transportGO:00986622070.032
ribose phosphate metabolic processGO:00196932910.032
negative regulation of molecular functionGO:00440922580.031
response to oxygen radicalGO:0000305160.030
membrane organizationGO:00610242450.030
purine ribonucleoside metabolic processGO:00461282410.029
nucleotide metabolic processGO:00091173320.029
cell redox homeostasisGO:004545460.029
organic acid transportGO:00158491010.029
purine containing compound metabolic processGO:00725213110.027
regulation of cellular response to stressGO:00801351590.027
heterocycle catabolic processGO:00467002800.027
sensory organ morphogenesisGO:00905962420.027
sensory perceptionGO:00076002450.027
regulation of organelle organizationGO:00330432890.026
response to acid chemicalGO:00011011110.026
cellular chemical homeostasisGO:00550822150.026
cellular nitrogen compound catabolic processGO:00442702800.025
skeletal system developmentGO:00015013560.025
regulation of kinase activityGO:00435492490.025
selenium compound metabolic processGO:000188730.025
monocarboxylic acid metabolic processGO:00327871910.025
cofactor metabolic processGO:0051186800.025
gland developmentGO:00487323300.025
carboxylic acid biosynthetic processGO:0046394860.025
purine containing compound catabolic processGO:00725232130.024
negative regulation of cellular amino acid metabolic processGO:004576300.024
ras protein signal transductionGO:0007265770.024
regulation of reactive oxygen species metabolic processGO:2000377400.024
positive regulation of protein modification processGO:00314012990.024
negative regulation of cell proliferationGO:00082852960.023
organophosphate catabolic processGO:00464342320.023
regulation of cytokine productionGO:00018172660.023
regulation of transferase activityGO:00513382630.023
cellular response to dna damage stimulusGO:00069742070.023
organonitrogen compound catabolic processGO:19015652640.023
response to vitamin aGO:003318910.023
cell type specific apoptotic processGO:00972852680.023
cellular metal ion homeostasisGO:00068751510.022
myeloid cell homeostasisGO:00022621140.022
cellular response to lipidGO:00713961450.022
negative regulation of phosphate metabolic processGO:00459361840.022
cytokine productionGO:00018163190.022
positive regulation of protein phosphorylationGO:00019342420.022
small gtpase mediated signal transductionGO:0007264970.022
glycosyl compound catabolic processGO:19016582060.021
purine ribonucleoside catabolic processGO:00461302050.021
positive regulation of cell deathGO:00109422240.021
cellular ion homeostasisGO:00068731650.021
regulation of protein kinase activityGO:00458592320.021
aromatic compound catabolic processGO:00194392860.021
posttranscriptional regulation of gene expressionGO:00106081550.021
action potentialGO:0001508780.021
locomotory behaviorGO:00076261950.020
purine nucleoside catabolic processGO:00061522050.020
endomembrane system organizationGO:00102561470.020
organic hydroxy compound metabolic processGO:19016152030.020
intracellular protein transportGO:00068862040.020
purine nucleoside triphosphate metabolic processGO:00091442260.020
response to reactive oxygen speciesGO:0000302560.020
divalent inorganic cation transportGO:00725111780.020
sequestering of calcium ionGO:0051208180.020
carboxylic acid transportGO:00469421000.020
purine nucleotide catabolic processGO:00061952110.020
regulation of clathrin mediated endocytosisGO:200036940.020
negative regulation of cellular amine metabolic processGO:003323910.020
g protein coupled receptor signaling pathwayGO:00071862430.020
glycosyl compound metabolic processGO:19016572460.020
ribonucleotide metabolic processGO:00092592910.020
regulation of cell cycleGO:00517262810.020
glycoprotein metabolic processGO:00091001160.019
regulation of transmembrane transportGO:00347621280.019
negative regulation of phosphorus metabolic processGO:00105631840.019
transition metal ion transportGO:0000041380.019
response to lipopolysaccharideGO:00324961280.019
response to radiationGO:00093141650.019
respiratory system developmentGO:00605411900.019
regulation of purine nucleotide metabolic processGO:19005421690.019
glucose homeostasisGO:00425931280.019
neuronal action potentialGO:0019228540.019
blood circulationGO:00080151950.019
Human
cellular calcium ion homeostasisGO:00068741190.019
carbohydrate derivative catabolic processGO:19011362310.019
regulation of nucleotide catabolic processGO:00308111220.019
regulation of nucleotide metabolic processGO:00061401690.018
ribonucleoside triphosphate catabolic processGO:00092031990.018
regulation of hydrolase activityGO:00513362460.018
negative regulation of transferase activityGO:0051348850.018
organelle assemblyGO:00709251770.018
translationGO:0006412930.018
renal system developmentGO:00720012250.018
protein maturationGO:00516041760.018
divalent metal ion transportGO:00708381720.018
homeostasis of number of cellsGO:00488722100.018
camera type eye developmentGO:00430102660.018
glycoprotein biosynthetic processGO:0009101890.018
negative regulation of cellular component organizationGO:00511291940.018
leukocyte differentiationGO:00025213420.018
mitochondrion degradationGO:000042230.018
striated muscle tissue developmentGO:00147062930.018
negative regulation of intracellular signal transductionGO:19025321670.018
response to metal ionGO:0010038470.018
cellular response to hormone stimulusGO:00328701500.018
multicellular organismal signalingGO:0035637910.018
negative regulation of protein phosphorylationGO:00019331260.018
rho protein signal transductionGO:0007266320.018
respiratory tube developmentGO:00303231670.018
inflammatory responseGO:00069542440.018
forebrain developmentGO:00309003020.018
negative regulation of phosphorylationGO:00423261660.018
divalent inorganic cation homeostasisGO:00725071380.018
regulation of secretionGO:00510462740.018
developmental maturationGO:00217001930.018
organelle fissionGO:00482851700.018
multicellular organismal homeostasisGO:00488711640.018
purine nucleoside metabolic processGO:00422782410.017
regulation of cell activationGO:00508652890.017
regulation of defense responseGO:00313472330.017
transition metal ion homeostasisGO:0055076540.017
response to light stimulusGO:00094161350.017
carbohydrate homeostasisGO:00335001280.017
compound eye developmentGO:004874910.017
regulation of system processGO:00440572000.017
positive regulation of nucleotide catabolic processGO:0030813880.017
immune effector processGO:00022523210.017
cofactor biosynthetic processGO:0051188410.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
nucleoside metabolic processGO:00091162460.017
sulfur compound biosynthetic processGO:0044272370.017
purine ribonucleotide catabolic processGO:00091542080.017
lymphocyte differentiationGO:00300982420.017
regulation of cellular component biogenesisGO:00440871810.017
transmission of nerve impulseGO:0019226760.017
rab protein signal transductionGO:003248210.017
regulation of hormone levelsGO:00108172110.017
dephosphorylationGO:00163111290.016
ribonucleoside catabolic processGO:00424542060.016
cell adhesionGO:00071553290.016
regulation of protein localizationGO:00328802310.016
nucleoside triphosphate metabolic processGO:00091412300.016
fatty acid metabolic processGO:00066311210.016
urogenital system developmentGO:00016552610.016
protein processingGO:00164851630.016
positive regulation of reactive oxygen species metabolic processGO:2000379110.016
mrna metabolic processGO:0016071840.016
cellular divalent inorganic cation homeostasisGO:00725031270.016
regulation of purine nucleotide catabolic processGO:00331211220.016
nucleoside phosphate catabolic processGO:19012922220.016
glycerolipid metabolic processGO:00464861220.016
cellular response to cytokine stimulusGO:00713451890.016
organophosphate biosynthetic processGO:00904071220.016
phospholipid metabolic processGO:0006644870.016
maintenance of locationGO:0051235890.016
erythrocyte differentiationGO:0030218880.016
cytoplasmic transportGO:00164822340.016
positive regulation of gtpase activityGO:0043547850.016
actin cytoskeleton organizationGO:00300362200.016
acylglycerol metabolic processGO:0006639550.016
protein localization to organelleGO:00333651850.016
cellular protein complex assemblyGO:00436231160.016
mapk cascadeGO:00001652810.016
mitotic cell cycleGO:00002781950.016
sequestering of metal ionGO:0051238190.016
cell maturationGO:00484691270.016
positive regulation of cell developmentGO:00107202370.015
response to superoxideGO:0000303160.015
regulation of secretion by cellGO:19035302490.015
calcium ion transportGO:00068161590.015
muscle tissue developmentGO:00605373080.015
germ cell developmentGO:00072811850.015
alpha amino acid metabolic processGO:1901605590.015
lipid transportGO:0006869980.015
innate immune responseGO:00450871570.015
regulation of mapk cascadeGO:00434082480.015
regulation of lymphocyte activationGO:00512492400.015
organic anion transportGO:00157111370.015
positive regulation of apoptotic processGO:00430652170.015
positive regulation of purine nucleotide catabolic processGO:0033123880.015
regulation of gtp catabolic processGO:00331241130.015
positive regulation of purine nucleotide metabolic processGO:19005441140.015
regulation of ion transmembrane transportGO:00347651190.015
nucleotide catabolic processGO:00091662170.015
guanosine containing compound metabolic processGO:19010681440.015
amide transportGO:00428861380.015
muscle cell differentiationGO:00426922610.015
regulation of response to woundingGO:19030341890.015
embryonic organ morphogenesisGO:00485622760.015
positive regulation of nucleotide metabolic processGO:00459811140.015
nucleoside catabolic processGO:00091642060.015
synaptic transmissionGO:00072683290.014
iron ion homeostasisGO:0055072360.014
chromatin modificationGO:00165681870.014
response to molecule of bacterial originGO:00022371430.014
microtubule based processGO:00070172360.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.014
bone developmentGO:00603481200.014
establishment or maintenance of cytoskeleton polarityGO:003095220.014
axonogenesisGO:00074092740.014
positive regulation of hydrolase activityGO:00513451480.014
cellularizationGO:000734910.014
regulation of ras gtpase activityGO:0032318880.014
cofactor transportGO:005118140.014
multicellular organism growthGO:00352641610.014
asymmetric stem cell divisionGO:009872230.014
chemotaxisGO:00069352470.014
regulation of intracellular transportGO:00323861590.014
placenta developmentGO:00018901400.014
monocarboxylic acid biosynthetic processGO:0072330610.014
dna metabolic processGO:00062593030.014
epidermis developmentGO:00085441870.014
reactive nitrogen species metabolic processGO:200105700.014
calcium ion homeostasisGO:00550741270.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.013
positive regulation of nucleoside metabolic processGO:0045979910.013
response to nutrient levelsGO:00316671090.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
peptide transportGO:00158331330.013
neural tube developmentGO:00219151600.013
protein glycosylationGO:0006486550.013
lateral inhibitionGO:004633110.013
positive regulation of macroautophagyGO:001623930.013
gtp catabolic processGO:00061841430.013
regulation of body fluid levelsGO:00508781620.013
positive regulation of programmed cell deathGO:00430682180.013
microtubule cytoskeleton organizationGO:00002261570.013
histone modificationGO:00165701590.013
positive regulation of transferase activityGO:00513471670.013
regulation of neuron differentiationGO:00456642810.013
spermatid differentiationGO:00485151150.013
skin developmentGO:00435882200.013
positive regulation of kinase activityGO:00336741550.013
mitotic cell cycle processGO:19030471590.013
plasma membrane organizationGO:0007009900.013
hematopoietic progenitor cell differentiationGO:00022441430.013
gtp metabolic processGO:00460391440.013
nucleoside triphosphate catabolic processGO:00091432050.013
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.013
vitamin transmembrane transportGO:003546140.013
nucleocytoplasmic transportGO:00069131390.013
negative regulation of immune system processGO:00026832090.013
retrograde transport endosome to golgiGO:004214720.013
multi multicellular organism processGO:00447061090.013
nonribosomal peptide biosynthetic processGO:001918450.013
spermatid developmentGO:00072861080.013
wnt signaling pathwayGO:00160551880.013
blood vessel morphogenesisGO:00485142850.013
cellular response to acid chemicalGO:0071229680.013
ear developmentGO:00435832000.012
nuclear transportGO:00511691390.012
neuron deathGO:00709971540.012
anion transmembrane transportGO:0098656710.012
epithelial tube morphogenesisGO:00605623030.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
meiotic cell cycleGO:00513211220.012
monocarboxylic acid transportGO:0015718440.012
protein targetingGO:00066051430.012
generation of precursor metabolites and energyGO:00060911030.012
engulfment of apoptotic cellGO:004365230.012
ossificationGO:00015032160.012
negative regulation of mesenchymal cell proliferation involved in lung developmentGO:200079120.012
adult behaviorGO:00305341350.012
cytokine mediated signaling pathwayGO:00192211150.012
regulation of cell cycle processGO:00105641600.012
regulation of protein serine threonine kinase activityGO:00719001570.012
wound healingGO:00420601570.012
regulation of ossificationGO:00302781120.012
regulation of neuron deathGO:19012141340.012
hormone secretionGO:00468791280.012
male sex differentiationGO:00466611090.012
regulation of reactive oxygen species biosynthetic processGO:190342620.012
development of primary sexual characteristicsGO:00451371430.012
cellular response to organonitrogen compoundGO:00714171450.012
membrane lipid metabolic processGO:0006643530.012
lung developmentGO:00303241640.012
actin filament organizationGO:00070151130.012
regulation of cell adhesionGO:00301551540.012
cellular response to oxidative stressGO:0034599760.012
protein localization to nucleusGO:00345041210.012
regulation of multi organism processGO:00439001110.012
regulation of cell migrationGO:00303342190.012
digestive system developmentGO:00551232000.012
cognitionGO:00508901490.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
oocyte constructionGO:000730820.012
regulation of metal ion transportGO:00109591060.012
skeletal muscle organ developmentGO:00605381630.012
protein oligomerizationGO:0051259670.012
positive regulation of organelle organizationGO:00106381280.012
regulation of protein transportGO:00512231630.012
embryonic epithelial tube formationGO:00018381300.012
regulation of establishment of protein localizationGO:00702011810.012
regulation of lipid metabolic processGO:00192161180.011
antimicrobial peptide productionGO:000277520.011
tube closureGO:0060606910.011
polyamine catabolic processGO:000659820.011
amino acid transmembrane transportGO:0003333370.011
nucleotide biosynthetic processGO:0009165780.011
response to growth factorGO:00708481980.011
regulation of bindingGO:00510981110.011
connective tissue developmentGO:00614481790.011
organic hydroxy compound transportGO:0015850930.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
meiotic nuclear divisionGO:00071261150.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
tissue homeostasisGO:00018941150.011
regulation of ion transportGO:00432692150.011
kidney developmentGO:00018222130.011
response to peptideGO:19016521360.011
muscle system processGO:00030121410.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
adiponectin activated signaling pathwayGO:003321140.011
anatomical structure homeostasisGO:00602491450.011
regulation of mitotic cell cycleGO:00073461260.011
interleukin 8 productionGO:003263740.011
alcohol metabolic processGO:00060661160.011
hexose metabolic processGO:0019318980.011
autophagyGO:0006914450.011
rhythmic processGO:00485111740.011
regulation of inflammatory responseGO:00507271470.011
ribonucleotide catabolic processGO:00092612080.011
protein localization to membraneGO:00726571080.011
nucleotide sugar transportGO:001578020.011
regulation of leukocyte differentiationGO:19021051590.011
sphingolipid biosynthetic processGO:0030148260.011
cellular response to extracellular stimulusGO:0031668810.011
nadph regenerationGO:000674020.011
response to alcoholGO:0097305480.011
response to starvationGO:0042594650.011
covalent chromatin modificationGO:00165691630.011
purine containing compound biosynthetic processGO:0072522700.011
peptidyl tyrosine phosphorylationGO:00181081430.011
establishment of protein localization to organelleGO:00725941180.011
rna processingGO:00063961050.011
regulation of translationGO:0006417710.011
positive regulation of nervous system developmentGO:00519622210.011
i kappab kinase nf kappab signalingGO:0007249850.011
glycosylationGO:0070085620.011
purine nucleotide biosynthetic processGO:0006164650.011
lipid localizationGO:00108761260.011
steroid metabolic processGO:00082021190.011
response to copper ionGO:004668830.011
positive regulation of gtp catabolic processGO:0033126850.011
ear morphogenesisGO:00424711180.011
cellular transition metal ion homeostasisGO:0046916320.011
protein targeting to vacuoleGO:000662330.011
fertilizationGO:00095661270.011
cellular component assembly involved in morphogenesisGO:00109271390.011
purine ribonucleotide biosynthetic processGO:0009152590.011
cellular carbohydrate metabolic processGO:00442621190.011
nuclear divisionGO:00002801580.011
neuron apoptotic processGO:00514021420.011
peptide secretionGO:00027901140.011
male gonad developmentGO:0008584880.011
regulation of cellular component sizeGO:00325351210.011
regulation of t cell activationGO:00508631700.010
lymphocyte proliferationGO:00466511640.010
fat cell differentiationGO:00454441600.010
positive regulation of protein kinase activityGO:00458601440.010
tissue remodelingGO:00487711020.010
b cell activationGO:00421131610.010
peptidyl lysine modificationGO:0018205770.010
insulin secretionGO:0030073890.010
stem cell differentiationGO:00488632680.010

Gclm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
nervous system diseaseDOID:86300.024
hematopoietic system diseaseDOID:7400.019
immune system diseaseDOID:291400.019
musculoskeletal system diseaseDOID:1700.019
connective tissue diseaseDOID:6500.019
bone diseaseDOID:008000100.018
disease of metabolismDOID:001466700.016
central nervous system diseaseDOID:33100.016
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
organ system cancerDOID:005068600.015
inherited metabolic disorderDOID:65500.013
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.011