Mus musculus

31 known processes

Trim21

tripartite motif-containing 21

(Aliases: Ssa1,Ro52)

Trim21 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense response to other organismGO:00985421970.983
innate immune responseGO:00450871570.971
Human Mouse
cellular response to interferon betaGO:0035458210.966
regulation of defense responseGO:00313472330.939
Mouse
positive regulation of innate immune responseGO:0045089800.938
Mouse
regulation of defense response to virus by hostGO:005069180.925
defense response to virusGO:0051607680.914
viral processGO:0016032410.898
response to interferon gammaGO:0034341340.848
defense response to protozoanGO:0042832250.829
immune effector processGO:00022523210.821
regulation of nlrp3 inflammasome complex assemblyGO:190022540.780
Mouse
innate immune response activating signal transductionGO:0002758500.775
Mouse
type i interferon productionGO:0032606290.757
regulation of innate immune responseGO:0045088910.757
Mouse
negative regulation of immune system processGO:00026832090.744
Mouse
interspecies interaction between organismsGO:0044419830.743
symbiosis encompassing mutualism through parasitismGO:0044403830.703
cellular response to lipopolysaccharideGO:0071222770.693
regulation of toll like receptor signaling pathwayGO:0034121200.690
Mouse
regulation of defense response to virusGO:0050688180.689
cytokine productionGO:00018163190.682
Mouse
response to protozoanGO:0001562280.664
pattern recognition receptor signaling pathwayGO:0002221470.660
Mouse
cellular response to molecule of bacterial originGO:0071219830.658
negative regulation of defense response to virus by hostGO:005068910.655
positive regulation of defense responseGO:00313491240.649
Mouse
regulation of cytokine productionGO:00018172660.645
Mouse
protein modification by small protein conjugation or removalGO:00706472070.629
Human Mouse
defense response to bacteriumGO:00427421190.610
cellular response to interferon gammaGO:0071346250.608
negative regulation of nlrp3 inflammasome complex assemblyGO:190022620.599
Mouse
interferon beta productionGO:0032608160.599
negative regulation of defense responseGO:0031348770.596
protein modification by small protein conjugationGO:00324461870.590
Human Mouse
positive regulation of interferon alpha productionGO:003272740.587
cd8 positive alpha beta t cell proliferationGO:003574010.581
leukocyte mediated cytotoxicityGO:0001909620.551
immune response regulating signaling pathwayGO:00027641250.546
Mouse
cellular response to cytokine stimulusGO:00713451890.541
regulation of response to biotic stimulusGO:0002831380.537
positive regulation of type i interferon mediated signaling pathwayGO:006034040.535
negative regulation of cytokine productionGO:0001818840.523
Mouse
positive regulation of viral genome replicationGO:004507020.515
positive regulation of rig i signaling pathwayGO:190024610.511
rig i signaling pathwayGO:003952940.510
immune response activating signal transductionGO:00027571160.482
Mouse
cellular response to type i interferonGO:0071357100.478
response to type i interferonGO:0034340120.476
toll like receptor signaling pathwayGO:0002224380.471
Mouse
natural killer cell proliferationGO:000178730.467
regulation of myd88 independent toll like receptor signaling pathwayGO:003412710.449
response to interferon betaGO:0035456220.442
regulation of interferon alpha productionGO:003264750.435
negative regulation of cell proliferationGO:00082852960.418
positive regulation of type i interferon productionGO:0032481140.413
positive regulation of cytokine productionGO:00018191740.412
activation of immune responseGO:00022531380.406
Mouse
response to lipopolysaccharideGO:00324961280.405
response to molecule of bacterial originGO:00022371430.396
viral life cycleGO:0019058360.396
regulation of type i interferon productionGO:0032479220.390
schwann cell proliferationGO:001401020.387
regulation of type i interferon mediated signaling pathwayGO:006033870.372
activation of innate immune responseGO:0002218560.365
Mouse
i kappab kinase nf kappab signalingGO:0007249850.357
negative regulation of protein metabolic processGO:00512482820.353
Human
regulation of natural killer cell mediated cytotoxicityGO:0042269190.352
cellular response to lipidGO:00713961450.339
citrate metabolic processGO:000610130.339
positive regulation of immune effector processGO:00026991070.338
cellular response to biotic stimulusGO:0071216920.325
type i interferon signaling pathwayGO:0060337100.324
protein catabolic processGO:00301632210.313
Mouse
positive regulation of actin nucleationGO:005112730.290
Mouse
regulation of cell activationGO:00508652890.286
negative regulation of multi organism processGO:0043901680.272
Human Mouse
positive regulation of natural killer cell mediated immunityGO:0002717160.272
negative regulation of nervous system developmentGO:00519611560.270
Mouse
cell killingGO:0001906670.268
lipopolysaccharide mediated signaling pathwayGO:0031663250.261
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.254
erythrocyte differentiationGO:0030218880.248
Mouse
regulation of cytokine biosynthetic processGO:0042035590.246
positive regulation of cytokine biosynthetic processGO:0042108400.243
aromatic compound catabolic processGO:00194392860.242
mast cell proliferationGO:007066240.235
protein ubiquitinationGO:00165671710.231
Human Mouse
regulation of myd88 dependent toll like receptor signaling pathwayGO:003412420.227
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.227
b cell activationGO:00421131610.226
response to dsrnaGO:0043331300.225
leukocyte mediated immunityGO:00024431740.220
negative regulation of toll like receptor signaling pathwayGO:0034122140.220
Mouse
cellular macromolecule catabolic processGO:00442652060.218
regulation of interferon beta productionGO:0032648130.216
gene silencing by mirnaGO:0035195100.209
negative regulation of viral processGO:0048525230.206
Human Mouse
regulation of rig i signaling pathwayGO:003953520.205
regulation of adaptive immune responseGO:0002819900.204
regulation of cell cycleGO:00517262810.204
Human
dna metabolic processGO:00062593030.204
entry into cell of other organism involved in symbiotic interactionGO:0051806150.197
regulation of natural killer cell differentiationGO:0032823110.196
regulation of lymphocyte activationGO:00512492400.195
t cell differentiationGO:00302171740.193
regulation of lymphocyte proliferationGO:00506701170.191
regulation of interferon gamma productionGO:0032649570.190
regulation of b cell activationGO:0050864810.187
regulation of interferon beta biosynthetic processGO:004535740.186
regulation of cd8 positive alpha beta t cell proliferationGO:200056410.186
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.185
lymphocyte proliferationGO:00466511640.184
organic cyclic compound catabolic processGO:19013612950.181
cellular response to dna damage stimulusGO:00069742070.181
alpha beta t cell differentiation involved in immune responseGO:0002293300.179
myeloid cell differentiationGO:00300992330.178
Mouse
cytoplasmic transportGO:00164822340.171
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.169
adaptive immune responseGO:00022501550.169
protein importGO:00170381010.165
intracellular protein transportGO:00068862040.164
reactive oxygen species metabolic processGO:0072593840.162
Mouse
lymphocyte differentiationGO:00300982420.157
glycosyl compound metabolic processGO:19016572460.157
negative regulation of immune effector processGO:0002698550.156
myeloid cell homeostasisGO:00022621140.155
Mouse
regulation of mast cell proliferationGO:007066640.155
regulation of lymphocyte mediated immunityGO:0002706840.154
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.154
Human
b cell activation involved in immune responseGO:0002312500.153
natural killer cell mediated cytotoxicityGO:0042267290.151
cell fate commitmentGO:00451652100.151
jak stat cascade involved in growth hormone signaling pathwayGO:006039740.151
proteolysis involved in cellular protein catabolic processGO:00516031470.151
positive regulation of cell activationGO:00508671580.151
cell activation involved in immune responseGO:00022631260.149
progesterone metabolic processGO:004244840.147
t cell activationGO:00421102890.146
leukocyte proliferationGO:00706611720.145
negative regulation of cell developmentGO:00107211690.144
Mouse
defense response to gram negative bacteriumGO:0050829280.143
leukocyte differentiationGO:00025213420.141
somatic cell dna recombinationGO:0016444510.139
negative regulation of protein modification processGO:00314001630.138
Human
response to granulocyte macrophage colony stimulating factorGO:009701230.138
cytokine biosynthetic processGO:0042089680.138
purine ribonucleotide catabolic processGO:00091542080.137
creatinine metabolic processGO:004644930.136
positive regulation of interferon beta productionGO:003272880.136
regulation of leukocyte differentiationGO:19021051590.135
natural killer cell activationGO:0030101440.134
regulation of t cell activationGO:00508631700.130
cytoplasmic pattern recognition receptor signaling pathway in response to virusGO:003952840.130
negative regulation of cellular protein metabolic processGO:00322692470.129
Human
regulation of reactive oxygen species metabolic processGO:2000377400.129
Mouse
alpha beta t cell activation involved in immune responseGO:0002287310.129
nucleocytoplasmic transportGO:00069131390.125
activation of cysteine type endopeptidase activityGO:0097202270.123
interaction with hostGO:0051701220.122
cd4 positive alpha beta t cell lineage commitmentGO:004337360.122
positive regulation of peptidase activityGO:0010952490.121
taurine metabolic processGO:001953040.120
cytokine metabolic processGO:0042107710.119
development of secondary male sexual characteristicsGO:004654430.118
positive regulation of proteolysisGO:0045862850.118
viral genome replicationGO:0019079170.118
positive regulation of t cell mediated cytotoxicityGO:0001916150.115
leukocyte activation involved in immune responseGO:00023661260.113
regulation of mast cell differentiationGO:006037530.113
nucleotide catabolic processGO:00091662170.112
cellular nitrogen compound catabolic processGO:00442702800.111
negative regulation of phosphate metabolic processGO:00459361840.110
lymphocyte mediated immunityGO:00024491390.110
positive regulation of response to cytokine stimulusGO:0060760110.109
glycosyl compound catabolic processGO:19016582060.108
positive t cell selectionGO:0043368230.108
myeloid leukocyte differentiationGO:00025731190.108
production of molecular mediator of immune responseGO:00024401030.107
cellular response to interferon alphaGO:003545740.106
regulation of interleukin 2 productionGO:0032663280.106
nucleotide metabolic processGO:00091173320.105
protein maturationGO:00516041760.105
positive regulation of cysteine type endopeptidase activityGO:2001056390.105
regulation of cysteine type endopeptidase activityGO:2000116650.104
positive regulation of lymphocyte differentiationGO:0045621610.104
response to organic cyclic compoundGO:00140701980.104
ribonucleoside triphosphate metabolic processGO:00091992200.103
ribonucleotide metabolic processGO:00092592910.103
cellular amino acid metabolic processGO:00065201030.102
regulation of leukocyte proliferationGO:00706631210.102
regulation of natural killer cell activationGO:0032814220.101
positive regulation of natural killer cell mediated cytotoxicityGO:0045954160.100
regulation of t cell differentiationGO:0045580830.100
creatine metabolic processGO:000660040.099
somatic recombination of immunoglobulin gene segmentsGO:0016447420.097
t helper cell differentiationGO:0042093280.096
regulation of viral release from host cellGO:190218660.096
Human Mouse
ribose phosphate metabolic processGO:00196932910.096
macromolecule catabolic processGO:00090572810.096
Mouse
negative regulation of t cell activationGO:0050868650.095
organophosphate catabolic processGO:00464342320.094
protein processingGO:00164851630.094
regulation of leukocyte apoptotic processGO:2000106560.094
valine metabolic processGO:000657340.094
natural killer cell mediated immunityGO:0002228290.093
immunoglobulin mediated immune responseGO:0016064690.093
lymphocyte activation involved in immune responseGO:0002285930.092
regulation of multi organism processGO:00439001110.092
nucleoside phosphate metabolic processGO:00067533380.092
negative regulation of cell activationGO:00508661110.091
nucleobase containing small molecule metabolic processGO:00550863520.091
regulation of lymphocyte differentiationGO:00456191070.090
myd88 independent toll like receptor signaling pathwayGO:000275630.090
regulation of endopeptidase activityGO:0052548890.090
t cell lineage commitmentGO:0002360130.089
positive regulation of endopeptidase activityGO:0010950430.088
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.088
protein methylationGO:0006479810.087
purine nucleoside triphosphate catabolic processGO:00091462030.086
nucleoside triphosphate metabolic processGO:00091412300.085
regulation of viral genome replicationGO:0045069130.085
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.084
purine nucleoside metabolic processGO:00422782410.084
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.084
isotype switchingGO:0045190360.084
viral gene expressionGO:001908030.084
Human Mouse
nucleoside metabolic processGO:00091162460.084
t helper 17 cell lineage commitmentGO:007254040.083
protein localization to nucleusGO:00345041210.083
purine nucleoside catabolic processGO:00061522050.083
t helper 1 cell lineage commitmentGO:000229620.083
regulation of leukocyte mediated cytotoxicityGO:0001910380.082
positive regulation of adaptive immune responseGO:0002821610.081
cd4 positive alpha beta t cell activationGO:0035710450.081
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.079
necrotic cell deathGO:0070265300.079
regulation of cell motilityGO:20001452360.078
mda 5 signaling pathwayGO:003953010.078
negative regulation of interferon beta productionGO:003268830.078
antigen processing and presentation of peptide antigenGO:0048002290.077
alpha beta t cell activationGO:0046631910.077
purine containing compound catabolic processGO:00725232130.077
interleukin 2 biosynthetic processGO:0042094150.077
positive regulation of apoptotic processGO:00430652170.077
regulation of proteolysisGO:00301621640.076
regulation of b cell differentiationGO:0045577230.076
extrinsic apoptotic signaling pathwayGO:00971911260.075
protein polyubiquitinationGO:0000209330.075
Human
purine ribonucleoside triphosphate catabolic processGO:00092071990.074
positive regulation of viral entry into host cellGO:004659830.074
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.074
regulation of defense response to bacteriumGO:190042430.074
positive regulation of leukocyte differentiationGO:1902107860.074
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.073
t cell proliferationGO:00420981200.073
regulation of macrophage fusionGO:003423930.072
cd4 positive alpha beta t cell differentiationGO:0043367410.072
defense response to gram positive bacteriumGO:0050830500.072
alpha beta t cell differentiationGO:0046632690.070
gamma delta t cell differentiationGO:0042492110.070
regulation of hormone levelsGO:00108172110.070
response to interleukin 2GO:007066920.070
nucleoside phosphate catabolic processGO:19012922220.069
multicellular organismal homeostasisGO:00488711640.069
t cell selectionGO:0045058340.069
negative regulation of phosphorylationGO:00423261660.068
regulation of alpha beta t cell proliferationGO:0046640180.068
fatty acid metabolic processGO:00066311210.068
response to interleukin 15GO:007067230.068
negative regulation of molecular functionGO:00440922580.068
Human
positive regulation of programmed cell deathGO:00430682180.067
cytokine mediated signaling pathwayGO:00192211150.067
regulation of peptidase activityGO:0052547960.067
dicarboxylic acid metabolic processGO:0043648180.066
autophagyGO:0006914450.066
male sex differentiationGO:00466611090.066
regulation of b cell mediated immunityGO:0002712370.066
entry into host cellGO:0030260150.064
negative regulation of cellular component organizationGO:00511291940.064
Mouse
regulation of inflammatory responseGO:00507271470.064
positive regulation of leukocyte mediated immunityGO:0002705700.064
regulation of interleukin 2 biosynthetic processGO:0045076130.063
alpha amino acid metabolic processGO:1901605590.063
development of primary female sexual characteristicsGO:0046545730.063
apoptotic signaling pathwayGO:00971903060.063
somatic diversification of immune receptorsGO:0002200530.062
protein import into nucleusGO:0006606950.062
negative regulation of glycolytic processGO:004582040.062
cellular response to granulocyte macrophage colony stimulating factor stimulusGO:009701130.062
regulation of response to woundingGO:19030341890.061
positive regulation of cell killingGO:0031343330.061
regulation of natural killer cell mediated immunityGO:0002715190.061
regulation of erythrocyte differentiationGO:0045646230.061
mitotic cell cycleGO:00002781950.061
regulation of cellular catabolic processGO:00313292420.061
organonitrogen compound catabolic processGO:19015652640.059
macromolecule methylationGO:00434141200.059
interleukin 2 productionGO:0032623330.059
negative regulation of defense response to virusGO:005068760.059
dna recombinationGO:0006310920.059
purine ribonucleotide metabolic processGO:00091502900.058
syncytium formationGO:0006949430.058
peptidyl amino acid modificationGO:00181933360.058
immunoglobulin productionGO:0002377730.058
regulation of hydrolase activityGO:00513362460.058
negative regulation of phosphorus metabolic processGO:00105631840.057
positive regulation of myeloid leukocyte differentiationGO:0002763260.057
covalent chromatin modificationGO:00165691630.057
ribonucleoside metabolic processGO:00091192450.057
negative regulation of viral release from host cellGO:190218760.056
Human Mouse
ubiquitin dependent protein catabolic processGO:00065111290.056
modulation of molecular function in other organismGO:004435910.056
response to growth factorGO:00708481980.055
chromatin organizationGO:00063252060.055
interferon gamma mediated signaling pathwayGO:006033350.055
negative regulation of innate immune responseGO:0045824170.055
regulation of activated t cell proliferationGO:0046006160.055
response to organonitrogen compoundGO:00102432460.055
stem cell developmentGO:00488642190.055
cellular amide metabolic processGO:0043603580.055
cellular protein catabolic processGO:00442571550.054
programmed necrotic cell deathGO:0097300280.054
purine nucleotide metabolic processGO:00061633020.054
positive regulation of lymphocyte mediated immunityGO:0002708620.054
t cell differentiation involved in immune responseGO:0002292300.054
homeostasis of number of cellsGO:00488722100.054
Mouse
positive regulation of lymphocyte activationGO:00512511400.053
epidermis developmentGO:00085441870.053
modification dependent macromolecule catabolic processGO:00436321330.053
positive regulation of mapk cascadeGO:00434101700.052
adhesion of symbiont to hostGO:004440680.052
modification dependent protein catabolic processGO:00199411330.052
t cell activation involved in immune responseGO:0002286430.052
regulation of cd8 positive alpha beta t cell activationGO:200118530.051
generation of precursor metabolites and energyGO:00060911030.051
negative regulation of lymphocyte activationGO:0051250910.051
antibacterial peptide productionGO:000277820.051
negative regulation of viral transcriptionGO:003289730.051
Human Mouse
leukocyte apoptotic processGO:0071887710.050
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.050
interferon alpha productionGO:003260770.050
t cell differentiation in thymusGO:0033077770.050
hematopoietic progenitor cell differentiationGO:00022441430.050
nucleoside catabolic processGO:00091642060.050
glial cell differentiationGO:00100011310.050
negative regulation of interferon alpha productionGO:003268710.050
purine nucleotide catabolic processGO:00061952110.049
mammary gland epithelium developmentGO:0061180650.049
cell type specific apoptotic processGO:00972852680.049
b cell mediated immunityGO:0019724710.048
negative regulation of viral entry into host cellGO:0046597100.048
Mouse
skin developmentGO:00435882200.048
nucleoside triphosphate catabolic processGO:00091432050.048
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.048
syncytium formation by plasma membrane fusionGO:0000768420.048
nuclear importGO:0051170950.048
positive regulation of gamma delta t cell differentiationGO:004558860.048
positive regulation of mast cell differentiationGO:006037610.048
temperature homeostasisGO:0001659260.047
stem cell differentiationGO:00488632680.047
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.047
regulation of t cell proliferationGO:0042129920.047
regulation of protein ubiquitinationGO:0031396520.046
gene silencing by rnaGO:0031047190.046
production of small rna involved in gene silencing by rnaGO:007091860.046
regulation of protein transportGO:00512231630.046
gland developmentGO:00487323300.045
positive regulation of natural killer cell activationGO:0032816150.045
macrophage fusionGO:003423830.045
stem cell maintenanceGO:00198271300.045
positive regulation of response to woundingGO:1903036660.045
regulation of reactive oxygen species biosynthetic processGO:190342620.044
isoleucine metabolic processGO:000654940.044
peptidyl lysine methylationGO:0018022290.044
regulation of intracellular transportGO:00323861590.044
regulation of intracellular protein transportGO:0033157820.044
positive regulation of b cell activationGO:0050871490.044
regulation of interleukin 1 alpha productionGO:003265040.043
posttranscriptional regulation of gene expressionGO:00106081550.043
Human
negative regulation of intracellular signal transductionGO:19025321670.043
hair follicle developmentGO:0001942850.043
alpha beta t cell lineage commitmentGO:000236370.043
positive regulation of cellular component biogenesisGO:0044089940.043
Mouse
carbohydrate metabolic processGO:00059752300.042
positive regulation of hydrolase activityGO:00513451480.042
positive regulation of cell deathGO:00109422240.042
nlrp3 inflammasome complex assemblyGO:004454650.042
Mouse
regulation of leukocyte mediated immunityGO:00027031040.041
regulation of autophagyGO:0010506300.041
isotype switching to ige isotypesGO:004828970.041
positive regulation of interferon gamma productionGO:0032729390.041
regulation of natural killer cell proliferationGO:003281720.041
entry into other organism involved in symbiotic interactionGO:0051828150.040
interleukin 4 mediated signaling pathwayGO:003577120.040
cellular ketone metabolic processGO:0042180840.040
myd88 dependent toll like receptor signaling pathwayGO:000275570.040
peptidyl tyrosine modificationGO:00182121450.040
leukocyte homeostasisGO:0001776790.039
positive regulation of interleukin 2 biosynthetic processGO:004508680.039
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathwayGO:003953120.039
response to peptide hormoneGO:00434341270.039
regulation of sequence specific dna binding transcription factor activityGO:00510901060.039
Human
regulation of type 2 immune responseGO:0002828180.039
negative regulation of protein phosphorylationGO:00019331260.038
peptidyl tyrosine phosphorylationGO:00181081430.038
positive regulation of production of molecular mediator of immune responseGO:0002702450.038
gliogenesisGO:00420631410.038
allantoin metabolic processGO:000025530.038
t cell mediated cytotoxicityGO:0001913260.038
heterocycle catabolic processGO:00467002800.038
germ cell developmentGO:00072811850.038
pyroptosisGO:007026980.038
ribonucleoside catabolic processGO:00424542060.038
positive regulation of leukocyte proliferationGO:0070665730.038
epithelial cell proliferationGO:00506731740.037
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.037
tumor necrosis factor productionGO:0032640500.037
Mouse
natural killer cell differentiationGO:0001779210.037
protein targetingGO:00066051430.037
regulation of myeloid cell differentiationGO:0045637960.037
negative regulation of type 2 immune responseGO:000282980.036
cellular lipid metabolic processGO:00442553230.036
female sex differentiationGO:0046660840.036
tumor necrosis factor superfamily cytokine productionGO:0071706510.036
Mouse
regulation of immunoglobulin productionGO:0002637420.036
negative regulation of angiogenesisGO:0016525250.036
b cell differentiationGO:0030183780.036
regulation of mapk cascadeGO:00434082480.036
hair follicle cell proliferationGO:007133530.036
lymphocyte homeostasisGO:0002260640.036
regulation of interleukin 6 productionGO:0032675550.035
Mouse
development of primary sexual characteristicsGO:00451371430.035
positive regulation of interleukin 1 alpha secretionGO:005071730.035
interferon gamma productionGO:0032609670.034
negative regulation of macrophage fusionGO:003424010.034
positive regulation of b cell differentiationGO:0045579130.034
purine ribonucleoside metabolic processGO:00461282410.034
multicellular organism growthGO:00352641610.034
cellular lactam metabolic processGO:007233830.034
negative regulation of t cell differentiationGO:0045581230.034
gene silencingGO:0016458380.034
epithelial tube formationGO:00721751300.034
regulation of gamma delta t cell activationGO:004664390.033
t cell homeostasisGO:0043029350.033
regulation of dna recombinationGO:0000018340.033
ribonucleoside triphosphate catabolic processGO:00092031990.033
ribonucleotide catabolic processGO:00092612080.033
cell adhesionGO:00071553290.033
methylationGO:00322591340.033
tricarboxylic acid metabolic processGO:007235050.032
regulation of mitotic cell cycleGO:00073461260.032
positive regulation of interleukin 2 productionGO:0032743190.032
regulation of protein localizationGO:00328802310.032
carbohydrate derivative catabolic processGO:19011362310.032
blood vessel morphogenesisGO:00485142850.032
negative regulation of regulatory t cell differentiationGO:004559020.032
positive regulation of myeloid cell differentiationGO:0045639430.032
regulation of transferase activityGO:00513382630.031
mucosal associated lymphoid tissue developmentGO:0048537120.031
gtp metabolic processGO:00460391440.031
entry into hostGO:0044409150.031
alpha beta t cell proliferationGO:0046633210.031
regulation of syncytium formation by plasma membrane fusionGO:0060142230.031
regulation of homeostatic processGO:00328441820.031
lipid localizationGO:00108761260.031
monocarboxylic acid metabolic processGO:00327871910.031
negative regulation of vasculature developmentGO:1901343260.031
positive regulation of myelinationGO:003164350.030
regulation of cell killingGO:0031341400.030
positive regulation of t cell activationGO:00508701010.030
negative regulation of rig i signaling pathwayGO:003953620.030
somatic diversification of immunoglobulinsGO:0016445430.030
regulation of angiogenesisGO:0045765810.030
neuron migrationGO:00017641220.029
protein localization to organelleGO:00333651850.029
regulation of glycolytic processGO:0006110100.029
t helper 1 type immune responseGO:0042088250.029
regulation of myeloid leukocyte differentiationGO:0002761580.029
purine containing compound metabolic processGO:00725213110.029
establishment of protein localization to organelleGO:00725941180.029
response to peptideGO:19016521360.029
positive regulation of inflammatory responseGO:0050729470.029
histone acetylationGO:0016573410.029
purine ribonucleoside triphosphate metabolic processGO:00092052200.029
regulation of protein complex assemblyGO:0043254830.029
Mouse
photoreceptor cell differentiationGO:0046530520.029
gamma delta t cell activationGO:0046629130.029
toll like receptor 7 signaling pathwayGO:003415440.028
steroid metabolic processGO:00082021190.028
interferon beta biosynthetic processGO:004535040.028
cellular response to organic cyclic compoundGO:0071407870.028

Trim21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.052
cancerDOID:16200.052
organ system cancerDOID:005068600.052
gastrointestinal system cancerDOID:311900.052