Mus musculus

0 known processes

Dtl

denticleless homolog (Drosophila)

(Aliases: 5730564G15Rik,Ramp,2810047L02Rik)

Dtl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cell cycle phase transitionGO:1901988480.924
Zebrafish
dna repairGO:00062811070.861
Human
regulation of cell cycle processGO:00105641600.802
Zebrafish
regulation of mitotic cell cycle phase transitionGO:1901990730.791
Zebrafish
dna metabolic processGO:00062593030.728
Human
dna recombinationGO:0006310920.710
organelle fissionGO:00482851700.652
meiosis iGO:0007127600.633
negative regulation of mitotic cell cycleGO:0045930580.615
Zebrafish
mitotic cell cycleGO:00002781950.610
Zebrafish
cell cycle checkpointGO:0000075470.594
Human Zebrafish
regulation of cell cycleGO:00517262810.592
Human Zebrafish Fly
cellular response to dna damage stimulusGO:00069742070.505
Human Zebrafish
mitotic cell cycle processGO:19030471590.474
Zebrafish
regulation of cell divisionGO:0051302760.465
regulation of cell cycle g2 m phase transitionGO:1902749100.460
centrosome organizationGO:0051297260.454
regulation of cell cycle phase transitionGO:1901987770.444
Zebrafish
organelle assemblyGO:00709251770.427
negative regulation of cell cycleGO:00457861230.388
Zebrafish
meiotic cell cycleGO:00513211220.370
centrosome cycleGO:0007098230.322
meiotic cell cycle processGO:1903046770.318
meiotic nuclear divisionGO:00071261150.303
microtubule cytoskeleton organizationGO:00002261570.286
genitalia developmentGO:0048806370.273
Worm
regulation of mitotic cell cycleGO:00073461260.265
Zebrafish
microtubule organizing center organizationGO:0031023280.257
regulation of mitosisGO:0007088290.248
cell divisionGO:00513011200.241
mitotic sister chromatid cohesionGO:000706410.239
male gamete generationGO:00482322850.233
female meiosis chromosome segregationGO:001632110.229
histone threonine phosphorylationGO:003540510.224
positive regulation of cell cycleGO:0045787920.222
spermatogenesisGO:00072832840.215
double strand break repairGO:0006302480.215
recombinational repairGO:0000725210.206
mitotic chromosome condensationGO:000707610.203
negative regulation of cellular component organizationGO:00511291940.194
nuclear divisionGO:00002801580.194
dna biosynthetic processGO:0071897220.187
Human
covalent chromatin modificationGO:00165691630.183
chromatin organizationGO:00063252060.182
dna endoreduplicationGO:004202340.182
centrosome separationGO:005129940.182
gonad developmentGO:00084061410.181
Worm
heterocycle catabolic processGO:00467002800.175
dna replicationGO:0006260520.171
regulation of organelle organizationGO:00330432890.167
purine nucleoside triphosphate metabolic processGO:00091442260.164
double strand break repair via homologous recombinationGO:0000724210.156
negative regulation of cell cycle processGO:0010948690.149
Zebrafish
ribonucleoside catabolic processGO:00424542060.147
mitotic sister chromatid segregationGO:0000070140.142
male meiosisGO:0007140370.142
mitotic nuclear divisionGO:0007067480.135
negative regulation of mitotic cell cycle phase transitionGO:1901991450.135
Zebrafish
mitotic centrosome separationGO:000710040.133
nucleoside triphosphate metabolic processGO:00091412300.131
negative regulation of organelle organizationGO:0010639900.125
organic cyclic compound catabolic processGO:19013612950.123
regulation of chromosome segregationGO:0051983210.122
chromatin modificationGO:00165681870.122
nucleoside metabolic processGO:00091162460.122
protein catabolic processGO:00301632210.118
Human
ribonucleoside triphosphate catabolic processGO:00092031990.115
intrinsic apoptotic signaling pathwayGO:00971931320.114
regulation of cellular amine metabolic processGO:0033238200.107
purine ribonucleotide metabolic processGO:00091502900.106
nucleotide catabolic processGO:00091662170.105
nucleoside phosphate metabolic processGO:00067533380.105
negative regulation of nuclear divisionGO:0051784190.102
purine nucleotide metabolic processGO:00061633020.101
chromatin assembly or disassemblyGO:0006333160.099
purine nucleoside catabolic processGO:00061522050.099
cellular amine metabolic processGO:0044106440.099
regulation of cellular amino acid metabolic processGO:000652150.096
nucleoside triphosphate catabolic processGO:00091432050.093
cellular nitrogen compound catabolic processGO:00442702800.092
organonitrogen compound catabolic processGO:19015652640.091
purine ribonucleoside metabolic processGO:00461282410.091
dna packagingGO:0006323300.088
regulation of chromosome organizationGO:0033044830.086
nucleoside phosphate catabolic processGO:19012922220.086
organophosphate catabolic processGO:00464342320.079
cellular macromolecule catabolic processGO:00442652060.079
Human
nucleoside catabolic processGO:00091642060.079
nucleoside monophosphate catabolic processGO:0009125590.078
cytokinesisGO:0000910170.078
mitotic cell cycle checkpointGO:0007093310.077
Zebrafish
microtubule based processGO:00070172360.076
regulation of nuclear divisionGO:0051783560.075
astral microtubule organizationGO:003095330.075
positive regulation of cell cycle processGO:0090068610.073
glycosyl compound catabolic processGO:19016582060.072
synapsisGO:0007129340.071
cilium morphogenesisGO:00602711020.070
response to light stimulusGO:00094161350.069
Human
cellular amino acid metabolic processGO:00065201030.069
macromolecule catabolic processGO:00090572810.068
Human
regulation of protein localizationGO:00328802310.068
negative regulation of cell divisionGO:0051782240.067
mitotic recombinationGO:000631230.066
cell cycle g1 s phase transitionGO:0044843570.065
maintenance of locationGO:0051235890.065
purine containing compound catabolic processGO:00725232130.064
carbohydrate derivative catabolic processGO:19011362310.063
dna conformation changeGO:0071103370.063
ribose phosphate metabolic processGO:00196932910.063
spindle assembly involved in mitosisGO:009030740.062
apoptotic signaling pathwayGO:00971903060.062
ribonucleoside triphosphate metabolic processGO:00091992200.062
purine nucleoside monophosphate metabolic processGO:0009126810.061
positive regulation of mitotic cell cycleGO:0045931410.061
peptidyl threonine phosphorylationGO:0018107310.060
female meiotic divisionGO:0007143210.060
heterochromatin organizationGO:007082840.060
gene silencingGO:0016458380.060
ribonucleoside metabolic processGO:00091192450.060
purine nucleoside triphosphate catabolic processGO:00091462030.059
glycosyl compound metabolic processGO:19016572460.059
spindle checkpointGO:0031577120.059
development of primary sexual characteristicsGO:00451371430.057
Worm
response to organic cyclic compoundGO:00140701980.055
microtubule nucleationGO:000702020.054
chromosome segregationGO:0007059480.054
spindle assembly involved in female meiosisGO:000705630.054
negative regulation of meiotic cell cycle phase transitionGO:190199430.053
atp catabolic processGO:0006200550.053
posttranscriptional regulation of gene expressionGO:00106081550.053
purine ribonucleoside monophosphate metabolic processGO:0009167800.052
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.052
regulation of meiosis iGO:006063170.051
purine ribonucleotide catabolic processGO:00091542080.051
dna dependent dna replication maintenance of fidelityGO:004500530.051
histone h3 k9 methylationGO:0051567170.051
aromatic compound catabolic processGO:00194392860.050
regulation of cellular ketone metabolic processGO:0010565660.050
g1 s transition of mitotic cell cycleGO:0000082570.049
purine nucleoside monophosphate catabolic processGO:0009128580.049
nucleobase containing small molecule metabolic processGO:00550863520.048
cell cycle g2 m phase transitionGO:0044839200.048
male meiosis iGO:0007141160.048
cellular response to organonitrogen compoundGO:00714171450.047
positive regulation of histone h3 k9 methylationGO:005157440.047
purine ribonucleoside triphosphate metabolic processGO:00092052200.047
spindle assembly involved in meiosisGO:009030640.047
establishment of organelle localizationGO:00516561220.046
purine ribonucleoside catabolic processGO:00461302050.046
sister chromatid segregationGO:0000819200.044
dna catabolic processGO:0006308190.044
negative regulation of mitosisGO:0045839100.044
regulation of nuclear cell cycle dna replicationGO:003326220.044
regulation of dna dependent dna replicationGO:009032980.043
female gamete generationGO:0007292740.043
positive regulation of apoptotic processGO:00430652170.043
metaphase plate congressionGO:005131020.042
multicellular organism growthGO:00352641610.042
Worm
positive regulation of cellular amine metabolic processGO:003324050.042
ribonucleoside monophosphate catabolic processGO:0009158570.042
spindle assemblyGO:0051225130.041
chromatin assemblyGO:0031497130.041
negative regulation of protein processingGO:0010955790.041
spermatid differentiationGO:00485151150.040
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.040
centrosome duplicationGO:0051298160.039
regulation of attachment of spindle microtubules to kinetochoreGO:005198830.039
dna catabolic process exonucleolyticGO:000073830.039
ribonucleotide metabolic processGO:00092592910.039
protein import into nucleusGO:0006606950.038
cell fate commitmentGO:00451652100.038
regulation of neural precursor cell proliferationGO:2000177700.038
histone modificationGO:00165701590.038
cellularizationGO:000734910.038
nucleoside monophosphate metabolic processGO:0009123850.038
regulation of apoptotic signaling pathwayGO:20012331970.038
protein importGO:00170381010.038
endomembrane system organizationGO:00102561470.038
ribonucleotide catabolic processGO:00092612080.038
spermatid developmentGO:00072861080.037
cellular ketone metabolic processGO:0042180840.037
atp metabolic processGO:0046034750.037
regulation of microtubule based processGO:0032886520.036
regulation of cytoskeleton organizationGO:00514931220.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
proteasomal protein catabolic processGO:0010498980.036
purine ribonucleoside triphosphate catabolic processGO:00092071990.036
peptidyl amino acid modificationGO:00181933360.036
germ cell developmentGO:00072811850.036
mitotic g2 dna damage checkpointGO:000709580.036
Zebrafish
amine metabolic processGO:0009308450.035
reciprocal meiotic recombinationGO:0007131160.035
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.034
histone acetylationGO:0016573410.034
chromosome organization involved in meiosisGO:0070192390.033
regulation of proteasomal protein catabolic processGO:0061136460.033
protein localization to organelleGO:00333651850.033
regulation of dna replicationGO:0006275170.032
regulation of microtubule cytoskeleton organizationGO:0070507370.032
intracellular protein transportGO:00068862040.031
histone phosphorylationGO:001657290.031
cellular component assembly involved in morphogenesisGO:00109271390.031
regulation of intracellular transportGO:00323861590.031
dna dependent dna replicationGO:0006261240.031
macromolecule methylationGO:00434141200.030
negative regulation of mitotic sister chromatid segregationGO:003304870.030
chromosome condensationGO:0030261100.030
regulation of histone modificationGO:0031056560.030
chromosome separationGO:0051304140.030
purine nucleotide catabolic processGO:00061952110.030
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.029
dna replication independent nucleosome assemblyGO:000633610.029
internal peptidyl lysine acetylationGO:0018393420.029
regulation of transferase activityGO:00513382630.029
establishment of meiotic spindle orientationGO:005129610.029
organelle localizationGO:00516401790.029
positive regulation of programmed cell deathGO:00430682180.029
positive regulation of cell deathGO:00109422240.028
nucleic acid phosphodiester bond hydrolysisGO:0090305490.028
regulation of cell cycle g1 s phase transitionGO:1902806350.028
establishment of protein localization to organelleGO:00725941180.028
reciprocal dna recombinationGO:0035825160.026
nucleotide metabolic processGO:00091173320.026
positive regulation of cell developmentGO:00107202370.026
negative regulation of protein maturationGO:1903318790.025
actin cytoskeleton organizationGO:00300362200.025
positive regulation of protein modification processGO:00314012990.025
response to organonitrogen compoundGO:00102432460.025
negative regulation of dna dependent dna replicationGO:200010410.025
regulation of histone acetylationGO:0035065190.024
regulation of cellular catabolic processGO:00313292420.024
purine containing compound metabolic processGO:00725213110.024
microtubule cytoskeleton organization involved in mitosisGO:190285040.024
regulation of cytoplasmic transportGO:19036491120.024
protein targetingGO:00066051430.023
rho protein signal transductionGO:0007266320.023
oogenesisGO:0048477560.023
purine ribonucleoside monophosphate catabolic processGO:0009169570.023
positive regulation of chromatin modificationGO:1903310280.023
regulation of cellular component sizeGO:00325351210.023
mitotic cytokinesisGO:000028140.023
chromatin mediated maintenance of transcriptionGO:004809620.023
protein maturationGO:00516041760.023
fertilizationGO:00095661270.023
ras protein signal transductionGO:0007265770.023
negative regulation of molecular functionGO:00440922580.023
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.023
production of molecular mediator of immune responseGO:00024401030.022
protein ubiquitinationGO:00165671710.022
Human
regulation of neuron differentiationGO:00456642810.022
striated muscle myosin thick filament assemblyGO:007168810.022
methylationGO:00322591340.022
negative regulation of cell proliferationGO:00082852960.022
meiotic chromosome segregationGO:0045132190.022
purine nucleoside metabolic processGO:00422782410.022
forebrain developmentGO:00309003020.022
nuclear importGO:0051170950.022
g2 m transition of mitotic cell cycleGO:0000086200.021
cellular response to growth factor stimulusGO:00713631970.021
histone h3 k9 acetylationGO:004397050.021
regulation of mitotic sister chromatid separationGO:0010965120.021
regulation of g1 s transition of mitotic cell cycleGO:2000045350.020
membrane organizationGO:00610242450.020
cation transportGO:00068123990.020
nucleocytoplasmic transportGO:00069131390.020
cellular response to cytokine stimulusGO:00713451890.020
dna catabolic process endonucleolyticGO:0000737150.020
nuclear transportGO:00511691390.020
dna damage checkpointGO:0000077260.020
Human Zebrafish
negative regulation of chromosome organizationGO:2001251300.020
negative regulation of protein metabolic processGO:00512482820.019
protein acylationGO:0043543640.019
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.019
peptidyl threonine modificationGO:0018210310.019
sister chromatid cohesionGO:0007062120.019
cellular response to abiotic stimulusGO:0071214560.019
microtubule slidingGO:005101210.018
heterochromatin assemblyGO:003150720.018
peptidyl lysine modificationGO:0018205770.018
regulation of establishment of protein localizationGO:00702011810.018
trophoblast giant cell differentiationGO:0060707150.018
protein localization to nucleusGO:00345041210.018
spindle organizationGO:0007051280.018
regulation of cellular protein catabolic processGO:1903362610.018
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.018
chromatin remodelingGO:0006338320.018
regulation of stem cell proliferationGO:0072091780.017
regulation of g2 m transition of mitotic cell cycleGO:0010389100.017
positive regulation of cell cycle phase transitionGO:1901989170.017
regulation of proteolysisGO:00301621640.017
cell type specific apoptotic processGO:00972852680.017
male gonad developmentGO:0008584880.017
negative regulation of cellular protein catabolic processGO:1903363220.017
regulation of cytokinesisGO:003246550.017
positive regulation of histone methylationGO:0031062160.017
response to radiationGO:00093141650.016
Human
myosin filament assemblyGO:003103420.016
blood vessel morphogenesisGO:00485142850.016
protein methylationGO:0006479810.016
single organism nuclear importGO:1902593950.016
male sex differentiationGO:00466611090.016
dephosphorylationGO:00163111290.016
muscle cell differentiationGO:00426922610.016
maintenance of location in cellGO:0051651240.016
chromatin remodeling at centromereGO:003105520.016
protein processingGO:00164851630.016
regulation of protein catabolic processGO:00421761080.016
development of primary male sexual characteristicsGO:0046546880.016
negative regulation of cellular protein metabolic processGO:00322692470.016
regulation of anatomical structure sizeGO:00900661780.015
regulation of asymmetric cell divisionGO:000978640.015
negative regulation of proteolysisGO:0045861740.015
negative regulation of cytoskeleton organizationGO:0051494360.015
regulation of meiotic cell cycleGO:0051445340.015
myosin filament organizationGO:003103330.015
internal protein amino acid acetylationGO:0006475420.015
ribonucleoside monophosphate metabolic processGO:0009161800.015
regulation of kinase activityGO:00435492490.015
positive regulation of cellular catabolic processGO:00313311480.015
regulation of sister chromatid cohesionGO:000706350.015
oocyte maturationGO:0001556180.015
cytoplasmic transportGO:00164822340.015
regulation of metaphase anaphase transition of cell cycleGO:190209990.015
g2 dna damage checkpointGO:003157280.014
Human Zebrafish
regulation of chromatin organizationGO:1902275570.014
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.014
negative regulation of cell developmentGO:00107211690.014
mitotic sister chromatid separationGO:005130690.014
regulation of hydrolase activityGO:00513362460.014
g0 to g1 transitionGO:004502330.014
regulation of dna recombinationGO:0000018340.014
positive regulation of chromosome segregationGO:005198440.014
cell cycle arrestGO:0007050370.014
single fertilizationGO:0007338820.014
leukocyte proliferationGO:00706611720.014
macromolecular complex disassemblyGO:0032984430.014
regulation of protein kinase activityGO:00458592320.013
histone h4 k20 methylationGO:003477080.013
regulation of protein processingGO:0070613960.013
regulation of cell projection organizationGO:00313442060.013
neuron migrationGO:00017641220.013
actomyosin structure organizationGO:0031032560.013
neural tube developmentGO:00219151600.013
negative regulation of phosphorus metabolic processGO:00105631840.013
ubiquitin dependent protein catabolic processGO:00065111290.013
Human
b cell activationGO:00421131610.013
mitochondrion organizationGO:00070051340.013
cellular response to organic cyclic compoundGO:0071407870.013
negative regulation of mitotic sister chromatid separationGO:200081670.013
negative regulation of cellular amino acid metabolic processGO:004576300.013
cellular response to gamma radiationGO:007148040.013
nuclear dna replicationGO:003326030.013
cell adhesionGO:00071553290.013
cellular protein complex assemblyGO:00436231160.013
dna integrity checkpointGO:0031570280.013
Human Zebrafish
endocytosisGO:00068971680.013
Worm
negative regulation of meiotic cell cycleGO:0051447140.013
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.013
negative regulation of mitotic metaphase anaphase transitionGO:004584170.013
epithelial tube formationGO:00721751300.013
mitotic spindle organizationGO:0007052100.013
regulation of histone h3 k9 methylationGO:005157080.012
telencephalon developmentGO:00215371860.012
positive regulation of mitotic cell cycle phase transitionGO:1901992170.012
anatomical structure homeostasisGO:00602491450.012
positive regulation of g0 to g1 transitionGO:007031820.012
regulation of dna endoreduplicationGO:003287530.012
positive regulation of protein kinase activityGO:00458601440.012
embryonic organ morphogenesisGO:00485622760.012
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244250.012
regulation of cell activationGO:00508652890.012
t cell activationGO:00421102890.012
placenta developmentGO:00018901400.012
cleavage furrow formationGO:003608920.012
oocyte differentiationGO:0009994350.012
body morphogenesisGO:0010171450.012
cellular response to radiationGO:0071478280.012
attachment of spindle microtubules to kinetochoreGO:000860840.011
divalent metal ion transportGO:00708381720.011
regulation of protein serine threonine kinase activityGO:00719001570.011
sensory perceptionGO:00076002450.011
regulation of epithelial cell proliferationGO:00506781410.011
developmental maturationGO:00217001930.011
smoothened signaling pathwayGO:00072241050.011
translesion synthesisGO:001998510.011
Human
negative regulation of cellular amine metabolic processGO:003323910.011
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051220.011
regulation of cytokine productionGO:00018172660.011
mitochondrial genome maintenanceGO:0000002150.011
meiotic cell cycle checkpointGO:003331320.011
lymphocyte mediated immunityGO:00024491390.011
locomotory behaviorGO:00076261950.011
rhythmic processGO:00485111740.011
regulation of chromatin modificationGO:1903308570.011
protein autophosphorylationGO:0046777610.011
neural tube formationGO:00018411080.011
histone h3 acetylationGO:0043966140.011
positive regulation of nervous system developmentGO:00519622210.011
t cell proliferationGO:00420981200.011
glucose homeostasisGO:00425931280.011
regulation of peptidase activityGO:0052547960.011
negative regulation of gene expression epigeneticGO:0045814150.011
negative regulation of histone methylationGO:0031061100.011
angiogenesisGO:00015252010.011
regulation of actin filament based processGO:0032970990.011
cellular response to light stimulusGO:0071482190.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
humoral immune responseGO:0006959570.011
regulation of lipid metabolic processGO:00192161180.011
regulation of lymphocyte activationGO:00512492400.010
negative regulation of bindingGO:0051100390.010
positive regulation of proteolysisGO:0045862850.010
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:000008330.010
actin filament organizationGO:00070151130.010
regulation of protein maturationGO:1903317960.010
regulation of double strand break repair via homologous recombinationGO:001056920.010
regulation of nucleocytoplasmic transportGO:0046822730.010
morphogenesis of embryonic epitheliumGO:00163311590.010
multi multicellular organism processGO:00447061090.010
b cell differentiationGO:0030183780.010
histone h4 k16 acetylationGO:004398430.010
positive regulation of transferase activityGO:00513471670.010
negative regulation of transferase activityGO:0051348850.010
positive regulation of dna endoreduplicationGO:003287720.010
stem cell differentiationGO:00488632680.010

Dtl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.253
immune system diseaseDOID:291400.253
hematopoietic system diseaseDOID:7400.253
aplastic anemiaDOID:1244900.058
anemiaDOID:235500.058
bone marrow diseaseDOID:496100.058
congenital hypoplastic anemiaDOID:134200.045
fanconi s anemiaDOID:1363600.043
disease of cellular proliferationDOID:1456600.039
organ system cancerDOID:005068600.019
cancerDOID:16200.019
breast cancerDOID:161200.018
thoracic cancerDOID:509300.018
physical disorderDOID:008001500.016
blood platelet diseaseDOID:221800.014
hemorrhagic diseaseDOID:221300.014
blood coagulation diseaseDOID:124700.014
congenital nervous system abnormalityDOID:249000.014