Mus musculus

38 known processes

Tmem176a

transmembrane protein 176A

(Aliases: AU040201,Keg2,0610011I04Rik,AU041743)

Tmem176a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
entry into hostGO:0044409150.697
entry into cell of other organism involved in symbiotic interactionGO:0051806150.648
leukocyte differentiationGO:00025213420.530
negative regulation of immune system processGO:00026832090.519
immune effector processGO:00022523210.485
dendritic cell differentiationGO:0097028260.465
positive regulation of programmed cell deathGO:00430682180.444
protein activation cascadeGO:0072376190.402
negative regulation of viral entry into host cellGO:0046597100.362
apoptotic signaling pathwayGO:00971903060.346
interspecies interaction between organismsGO:0044419830.340
movement in environment of other organism involved in symbiotic interactionGO:0052192150.242
mapk cascadeGO:00001652810.221
angiogenesisGO:00015252010.215
response to molecule of bacterial originGO:00022371430.210
viral entry into host cellGO:0046718150.196
cellular amino acid metabolic processGO:00065201030.190
adaptive immune responseGO:00022501550.184
inflammatory responseGO:00069542440.170
entry into other organism involved in symbiotic interactionGO:0051828150.167
regulation of apoptotic signaling pathwayGO:20012331970.157
cellular response to molecule of bacterial originGO:0071219830.151
cellular response to cytokine stimulusGO:00713451890.147
negative regulation of cell proliferationGO:00082852960.144
entry into host cellGO:0030260150.142
regulation of cellular amino acid metabolic processGO:000652150.141
response to lipopolysaccharideGO:00324961280.138
positive regulation of apoptotic signaling pathwayGO:2001235950.135
cellular ketone metabolic processGO:0042180840.130
regulation of cell motilityGO:20001452360.120
cytokine productionGO:00018163190.119
regulation of cellular amine metabolic processGO:0033238200.119
regulation of leukocyte differentiationGO:19021051590.118
glycosyl compound metabolic processGO:19016572460.118
leukocyte mediated cytotoxicityGO:0001909620.117
carbohydrate homeostasisGO:00335001280.116
circulatory system processGO:00030131970.113
intrinsic apoptotic signaling pathwayGO:00971931320.106
acute inflammatory responseGO:0002526410.098
ossificationGO:00015032160.087
viral processGO:0016032410.086
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.083
regulation of cell migrationGO:00303342190.083
cellular lipid metabolic processGO:00442553230.082
cellular response to lipidGO:00713961450.080
lung developmentGO:00303241640.078
negative regulation of multi organism processGO:0043901680.078
cell type specific apoptotic processGO:00972852680.073
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.068
regulation of cell activationGO:00508652890.067
defense response to other organismGO:00985421970.067
response to acid chemicalGO:00011011110.066
cellular response to thyroid hormone stimulusGO:009706710.066
protein kinase b signalingGO:0043491740.066
lipid localizationGO:00108761260.065
movement in host environmentGO:0052126150.064
lung morphogenesisGO:0060425500.064
regulation of secretionGO:00510462740.063
regulation of defense responseGO:00313472330.063
epithelial tube morphogenesisGO:00605623030.062
cellular amine metabolic processGO:0044106440.059
regulation of cytokine productionGO:00018172660.059
regulation of mapk cascadeGO:00434082480.058
positive regulation of cellular amino acid metabolic processGO:004576430.058
lipid biosynthetic processGO:00086101790.057
peptidyl amino acid modificationGO:00181933360.057
interleukin 8 productionGO:003263740.057
monosaccharide metabolic processGO:00059961060.056
regulation of system processGO:00440572000.056
posttranscriptional regulation of gene expressionGO:00106081550.055
humoral immune responseGO:0006959570.055
amine metabolic processGO:0009308450.054
regulation of protein localizationGO:00328802310.054
cellular response to dna damage stimulusGO:00069742070.053
male gamete generationGO:00482322850.051
positive regulation of apoptotic processGO:00430652170.050
positive regulation of cellular amine metabolic processGO:003324050.050
regulation of peptidase activityGO:0052547960.049
respiratory system developmentGO:00605411900.049
negative regulation of intracellular signal transductionGO:19025321670.047
cellular response to hormone stimulusGO:00328701500.047
chemotaxisGO:00069352470.047
morphogenesis of a branching epitheliumGO:00611381930.047
spermatogenesisGO:00072832840.047
regulation of proteolysisGO:00301621640.046
carbohydrate metabolic processGO:00059752300.046
response to nutrient levelsGO:00316671090.046
positive regulation of inflammatory responseGO:0050729470.045
symbiosis encompassing mutualism through parasitismGO:0044403830.044
regulation of cellular ketone metabolic processGO:0010565660.043
reactive oxygen species biosynthetic processGO:190340980.043
protein secretionGO:00093061110.043
guanosine containing compound metabolic processGO:19010681440.041
regulation of hydrolase activityGO:00513362460.041
positive regulation of macrophage activationGO:0043032100.041
cytokine secretionGO:0050663720.041
regionalizationGO:00030023370.040
endocytosisGO:00068971680.040
innate immune responseGO:00450871570.040
regulation of membrane potentialGO:00423911920.040
glycerolipid metabolic processGO:00464861220.040
aromatic compound catabolic processGO:00194392860.039
nucleotide metabolic processGO:00091173320.039
positive regulation of reactive oxygen species biosynthetic processGO:190342820.039
carbohydrate derivative catabolic processGO:19011362310.039
cellular response to nutrient levelsGO:0031669640.038
regulation of endopeptidase activityGO:0052548890.038
regulation of establishment of protein localizationGO:00702011810.038
interaction with hostGO:0051701220.038
carboxylic acid transportGO:00469421000.037
positive regulation of protein transportGO:0051222930.037
striated muscle tissue developmentGO:00147062930.037
muscle system processGO:00030121410.037
wound healingGO:00420601570.036
lipid transportGO:0006869980.036
regulation of reactive oxygen species biosynthetic processGO:190342620.036
regulation of multi organism processGO:00439001110.036
epithelial tube branching involved in lung morphogenesisGO:0060441280.035
small molecule biosynthetic processGO:00442831320.035
regulation of inflammatory responseGO:00507271470.035
metal ion homeostasisGO:00550651890.035
lymphocyte mediated immunityGO:00024491390.035
neuronal action potentialGO:0019228540.035
epithelial cell proliferationGO:00506731740.035
positive regulation of cell deathGO:00109422240.034
notch signaling pathwayGO:0007219710.034
purine ribonucleoside triphosphate catabolic processGO:00092071990.034
activation of immune responseGO:00022531380.034
regulation of protein kinase activityGO:00458592320.034
triglyceride metabolic processGO:0006641510.033
nucleoside metabolic processGO:00091162460.033
viral life cycleGO:0019058360.033
response to insulinGO:00328681000.033
leukocyte mediated immunityGO:00024431740.033
purine ribonucleotide catabolic processGO:00091542080.032
blood vessel morphogenesisGO:00485142850.032
hexose metabolic processGO:0019318980.032
blood circulationGO:00080151950.032
neuromuscular processGO:0050905990.032
segmentationGO:0035282930.032
respiratory tube developmentGO:00303231670.031
regulation of ossificationGO:00302781120.030
muscle cell differentiationGO:00426922610.030
response to interferon gammaGO:0034341340.030
maintenance of locationGO:0051235890.030
muscle tissue developmentGO:00605373080.030
cation homeostasisGO:00550802120.030
organic acid transportGO:00158491010.030
regulation of erk1 and erk2 cascadeGO:0070372710.029
ribonucleoside catabolic processGO:00424542060.029
cellular modified amino acid metabolic processGO:0006575630.029
regulation of secretion by cellGO:19035302490.029
negative regulation of viral genome replicationGO:0045071100.028
type b pancreatic cell proliferationGO:0044342100.028
vitamin metabolic processGO:0006766230.028
positive regulation of rho gtpase activityGO:0032321410.028
myeloid cell differentiationGO:00300992330.027
purine nucleoside triphosphate metabolic processGO:00091442260.027
bone developmentGO:00603481200.027
regulation of osteoblast differentiationGO:0045667670.027
cell substrate adhesionGO:00315891300.027
complement activationGO:0006956160.027
regulation of neuron deathGO:19012141340.027
sensory perception of soundGO:0007605970.026
small gtpase mediated signal transductionGO:0007264970.026
epidermis morphogenesisGO:0048730330.026
cellular homeostasisGO:00197252400.026
purine nucleoside catabolic processGO:00061522050.026
regulation of protein kinase b signalingGO:0051896560.026
alcohol metabolic processGO:00060661160.025
carbon catabolite regulation of transcriptionGO:004599040.025
organonitrogen compound biosynthetic processGO:19015661920.025
negative regulation of cell activationGO:00508661110.025
reactive oxygen species metabolic processGO:0072593840.025
macromolecule catabolic processGO:00090572810.025
positive regulation of cytokine productionGO:00018191740.025
purine ribonucleoside triphosphate metabolic processGO:00092052200.025
reactive nitrogen species metabolic processGO:200105700.024
macromolecule glycosylationGO:0043413550.024
response to extracellular stimulusGO:00099911270.024
rac protein signal transductionGO:0016601130.024
regulation of transferase activityGO:00513382630.024
response to type i interferonGO:0034340120.024
cellular amide metabolic processGO:0043603580.024
regulation of cytokine secretionGO:0050707610.024
nuclear transportGO:00511691390.024
purine ribonucleoside metabolic processGO:00461282410.024
cellular response to carbohydrate stimulusGO:0071322500.023
organic anion transportGO:00157111370.023
positive regulation of cell activationGO:00508671580.023
regulation of acute inflammatory responseGO:0002673270.023
regulation of epithelial cell proliferationGO:00506781410.023
blood coagulationGO:0007596760.023
regulation of angiogenesisGO:0045765810.022
homeostasis of number of cellsGO:00488722100.022
divalent inorganic cation transportGO:00725111780.022
ceramide biosynthetic processGO:0046513200.022
monocarboxylic acid metabolic processGO:00327871910.022
lymphocyte activation involved in immune responseGO:0002285930.022
interleukin 8 secretionGO:007260630.022
detection of molecule of bacterial originGO:003249020.022
purine ribonucleoside catabolic processGO:00461302050.021
viral genome replicationGO:0019079170.021
cellular response to lipopolysaccharideGO:0071222770.021
organonitrogen compound catabolic processGO:19015652640.021
positive regulation of angiogenesisGO:0045766460.021
cell activation involved in immune responseGO:00022631260.021
regulation of blood vessel sizeGO:0050880560.021
hindbrain developmentGO:00309021280.021
negative regulation of cell motilityGO:2000146610.021
response to organonitrogen compoundGO:00102432460.020
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.020
positive regulation of innate immune responseGO:0045089800.020
positive regulation of secretionGO:00510471300.020
cellular nitrogen compound catabolic processGO:00442702800.020
morphogenesis of a branching structureGO:00017632030.020
regulation of protein secretionGO:0050708820.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.020
positive regulation of immune effector processGO:00026991070.019
regulation of cellular catabolic processGO:00313292420.019
immunoglobulin mediated immune responseGO:0016064690.019
cation transportGO:00068123990.019
fat soluble vitamin biosynthetic processGO:004236240.019
carbohydrate derivative biosynthetic processGO:19011371830.019
negative regulation of protein metabolic processGO:00512482820.019
anion transportGO:00068201770.019
negative regulation of proteolysisGO:0045861740.018
regulation of neuron differentiationGO:00456642810.018
positive regulation of reactive oxygen species metabolic processGO:2000379110.018
regulation of viral transcriptionGO:004678230.018
response to steroid hormoneGO:0048545560.018
endomembrane system organizationGO:00102561470.018
neuron deathGO:00709971540.018
endothelial cell developmentGO:0001885200.018
response to corticosteroneGO:005141210.018
cytokine mediated signaling pathwayGO:00192211150.017
negative regulation of cytokine productionGO:0001818840.017
t cell activationGO:00421102890.017
regulation of glucose metabolic processGO:0010906600.017
cellular response to extracellular stimulusGO:0031668810.017
embryonic organ morphogenesisGO:00485622760.017
t cell mediated immunityGO:0002456500.017
negative regulation of platelet derived growth factor receptor alpha signaling pathwayGO:200058420.017
carboxylic acid biosynthetic processGO:0046394860.017
protein importGO:00170381010.017
organic acid biosynthetic processGO:0016053860.017
cell killingGO:0001906670.017
regulation of ion transportGO:00432692150.017
regulation of protein maturationGO:1903317960.017
cell adhesionGO:00071553290.017
t cell differentiationGO:00302171740.017
negative regulation of cellular protein metabolic processGO:00322692470.017
positive regulation of behaviorGO:0048520400.017
regulation of blood pressureGO:0008217930.017
response to light stimulusGO:00094161350.016
membrane organizationGO:00610242450.016
cellular response to insulin stimulusGO:0032869780.016
purine containing compound metabolic processGO:00725213110.016
metanephric glomerular epithelial cell developmentGO:007231320.016
positive regulation of protein phosphorylationGO:00019342420.016
negative regulation of neuron differentiationGO:00456651010.016
muscle contractionGO:00069361010.016
leukocyte apoptotic processGO:0071887710.016
transition metal ion transportGO:0000041380.016
apoptotic cell clearanceGO:0043277170.016
glucose metabolic processGO:0006006920.016
regulation of organelle organizationGO:00330432890.016
nuclear importGO:0051170950.016
mitotic cell cycleGO:00002781950.016
nucleoside catabolic processGO:00091642060.016
cellular response to starvationGO:0009267570.016
positive regulation of protein modification processGO:00314012990.016
positive regulation of nervous system developmentGO:00519622210.016
regulation of platelet derived growth factor receptor signaling pathwayGO:001064090.016
mechanoreceptor differentiationGO:0042490670.016
negative regulation of complement activationGO:004591630.016
cyclic nucleotide metabolic processGO:0009187590.015
regulation of bindingGO:00510981110.015
gonad developmentGO:00084061410.015
activation of membrane attack complexGO:000190540.015
neuron apoptotic processGO:00514021420.015
regulation of syncytium formation by plasma membrane fusionGO:0060142230.015
positive regulation of mapk cascadeGO:00434101700.015
heterocycle catabolic processGO:00467002800.015
synaptic transmissionGO:00072683290.015
regulation of lipid metabolic processGO:00192161180.015
acute inflammatory response to antigenic stimulusGO:0002438120.015
positive regulation of cellular catabolic processGO:00313311480.015
response to inorganic substanceGO:0010035960.015
acylglycerol metabolic processGO:0006639550.015
peptidyl tyrosine modificationGO:00182121450.015
regulation of muscle system processGO:0090257800.015
negative regulation of defense responseGO:0031348770.015
oxidation reduction processGO:00551143420.014
cellular chemical homeostasisGO:00550822150.014
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.014
positive regulation of protein serine threonine kinase activityGO:00719021060.014
axonogenesisGO:00074092740.014
central nervous system neuron differentiationGO:00219531620.014
regulation of hormone levelsGO:00108172110.014
extrinsic apoptotic signaling pathwayGO:00971911260.014
positive regulation of protein kinase activityGO:00458601440.014
multicellular organismal macromolecule catabolic processGO:004426610.014
positive regulation of defense responseGO:00313491240.014
defense response to gram positive bacteriumGO:0050830500.014
regulation of kinase activityGO:00435492490.014
negative regulation of protein transportGO:0051224460.014
leukocyte migrationGO:00509001240.014
sensory perception of mechanical stimulusGO:00509541070.014
nucleoside phosphate metabolic processGO:00067533380.014
regulation of interleukin 8 secretionGO:200048220.014
cytochrome complex assemblyGO:001700430.014
defense response to virusGO:0051607680.014
regulation of body fluid levelsGO:00508781620.014
protein maturationGO:00516041760.014
branching morphogenesis of an epithelial tubeGO:00487541590.014
metencephalon developmentGO:0022037890.014
cellular protein complex assemblyGO:00436231160.013
multicellular organism growthGO:00352641610.013
cellular response to external stimulusGO:0071496880.013
engulfment of apoptotic cellGO:004365230.013
regulation of nucleotide metabolic processGO:00061401690.013
regulation of protein oligomerizationGO:003245940.013
monosaccharide biosynthetic processGO:0046364440.013
positive regulation of apoptotic cell clearanceGO:200042730.013
nucleoside triphosphate metabolic processGO:00091412300.013
b cell activationGO:00421131610.013
cellular response to monosaccharide stimulusGO:0071326470.013
regulation of vascular smooth muscle contractionGO:000305610.013
maintenance of epithelial cell apical basal polarityGO:004519920.013
extracellular structure organizationGO:00430621480.013
divalent metal ion transportGO:00708381720.013
ceramide metabolic processGO:0006672310.013
somitogenesisGO:0001756690.013
negative regulation of cell migrationGO:0030336590.013
fatty acid biosynthetic processGO:0006633410.013
response to interferon betaGO:0035456220.013
sensory system developmentGO:004888030.013
positive regulation of cytokine secretionGO:0050715410.013
ear developmentGO:00435832000.013
endothelial cell differentiationGO:0045446410.013
protein n linked glycosylationGO:0006487120.013
glucose homeostasisGO:00425931280.013
negative regulation of growthGO:0045926990.012
organic hydroxy compound metabolic processGO:19016152030.012
locomotory behaviorGO:00076261950.012
heart processGO:0003015940.012
nucleocytoplasmic transportGO:00069131390.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
negative regulation of viral processGO:0048525230.012
calcium ion transportGO:00068161590.012
cellular response to biotic stimulusGO:0071216920.012
regulation of homeostatic processGO:00328441820.012
regulation of viral entry into host cellGO:0046596120.012
cerebellar cortex developmentGO:0021695480.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
regulation of protein transportGO:00512231630.012
ribose phosphate metabolic processGO:00196932910.012
activation of adenylate cyclase activityGO:000719040.012
skeletal muscle organ developmentGO:00605381630.012
negative regulation of phosphorus metabolic processGO:00105631840.012
action potentialGO:0001508780.012
nucleobase containing small molecule metabolic processGO:00550863520.012
rhythmic processGO:00485111740.012
epidermis developmentGO:00085441870.012
negative regulation of inflammatory responseGO:0050728610.012
ras protein signal transductionGO:0007265770.012
cognitionGO:00508901490.012
myeloid cell homeostasisGO:00022621140.012
learning or memoryGO:00076111480.012
hindbrain morphogenesisGO:0021575460.012
cellular metal ion homeostasisGO:00068751510.012
phagolysosome assemblyGO:000184530.012
ribonucleoside metabolic processGO:00091192450.012
establishment of protein localization to organelleGO:00725941180.012
positive regulation of ras gtpase activityGO:0032320650.012
regulation of interleukin 8 productionGO:003267730.012
nucleotide catabolic processGO:00091662170.011
regulation of purine nucleotide metabolic processGO:19005421690.011
nucleoside triphosphate catabolic processGO:00091432050.011
actin filament polymerizationGO:0030041440.011
regulation of protein stabilityGO:0031647520.011
water homeostasisGO:0030104270.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.011
regulation of neuron apoptotic processGO:00435231220.011
regulation of nucleoside metabolic processGO:00091181300.011
icosanoid transportGO:0071715140.011
positive regulation of nucleotide metabolic processGO:00459811140.011
organophosphate catabolic processGO:00464342320.011
macrophage activationGO:0042116270.011
peptidyl tyrosine phosphorylationGO:00181081430.011
positive regulation of transferase activityGO:00513471670.011
neural tube developmentGO:00219151600.011
ribonucleoside triphosphate metabolic processGO:00091992200.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
muscle cell developmentGO:00550011330.011
regulation of response to woundingGO:19030341890.011
negative regulation of molecular functionGO:00440922580.011
response to peptide hormoneGO:00434341270.011
steroid metabolic processGO:00082021190.011
positive regulation of osteoblast differentiationGO:0045669340.011
leukocyte proliferationGO:00706611720.011
negative regulation of nervous system developmentGO:00519611560.011
phagocytosisGO:0006909660.011
divalent inorganic cation homeostasisGO:00725071380.011
sensory perceptionGO:00076002450.011
inflammatory response to antigenic stimulusGO:0002437300.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.011
defecationGO:003042110.011
lateral line system developmentGO:004892510.010
cellular divalent inorganic anion homeostasisGO:007250130.010
hair follicle morphogenesisGO:0031069290.010
negative regulation of lymphocyte activationGO:0051250910.010
germ cell developmentGO:00072811850.010
regulation of cell cycle phase transitionGO:1901987770.010
lysosome organizationGO:0007040210.010
protein localization to organelleGO:00333651850.010
intracellular protein transportGO:00068862040.010
lipopolysaccharide mediated signaling pathwayGO:0031663250.010
regulation of protein import into nucleusGO:0042306520.010
lymphocyte differentiationGO:00300982420.010
negative regulation of endopeptidase activityGO:0010951440.010
female sex differentiationGO:0046660840.010
myotube differentiationGO:00149021050.010
regulation of macrophage activationGO:0043030170.010
protein localization to nucleusGO:00345041210.010
regulation of cell cycle processGO:00105641600.010
nucleoside phosphate catabolic processGO:19012922220.010
positive regulation of secretion by cellGO:19035321140.010
positive regulation of cell migrationGO:00303351090.010

Tmem176a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.143
disease of anatomical entityDOID:700.143
disease of metabolismDOID:001466700.080
inherited metabolic disorderDOID:65500.080
immune system diseaseDOID:291400.056
sensory system diseaseDOID:005015500.024
eye diseaseDOID:561400.024
retinal diseaseDOID:567900.024
eye and adnexa diseaseDOID:149200.024
lipid storage diseaseDOID:945500.021
lysosomal storage diseaseDOID:321100.021
central nervous system diseaseDOID:33100.017
primary immunodeficiency diseaseDOID:61200.013
hematopoietic system diseaseDOID:7400.011
integumentary system diseaseDOID:1600.011
bone diseaseDOID:008000100.011
musculoskeletal system diseaseDOID:1700.011
connective tissue diseaseDOID:6500.011
normocytic anemiaDOID:72000.011
hemolytic uremic syndromeDOID:1255400.011
hemolytic anemiaDOID:58300.011
anemiaDOID:235500.011