Mus musculus

96 known processes

Ddit4

DNA-damage-inducible transcript 4

(Aliases: Rtp801,5830413E08Rik,REDD1,dig2,AA415483)

Ddit4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular ketone metabolic processGO:0042180840.163
fat cell differentiationGO:00454441600.126
response to organonitrogen compoundGO:00102432460.114
cellular amino acid metabolic processGO:00065201030.098
negative regulation of protein metabolic processGO:00512482820.090
amine metabolic processGO:0009308450.088
negative regulation of molecular functionGO:00440922580.083
negative regulation of protein modification processGO:00314001630.082
regulation of cellular amino acid metabolic processGO:000652150.081
response to peptideGO:19016521360.081
regulation of cellular ketone metabolic processGO:0010565660.079
regulation of cellular amine metabolic processGO:0033238200.078
apoptotic signaling pathwayGO:00971903060.078
carbohydrate metabolic processGO:00059752300.076
negative regulation of cellular amino acid metabolic processGO:004576300.072
negative regulation of cell proliferationGO:00082852960.070
negative regulation of cellular protein metabolic processGO:00322692470.068
response to radiationGO:00093141650.064
negative regulation of phosphate metabolic processGO:00459361840.061
cellular response to organonitrogen compoundGO:00714171450.060
positive regulation of apoptotic processGO:00430652170.058
anion transportGO:00068201770.057
cation transportGO:00068123990.056
regulation of organelle organizationGO:00330432890.055
negative regulation of phosphorylationGO:00423261660.055
peptidyl amino acid modificationGO:00181933360.054
cellular lipid metabolic processGO:00442553230.053
response to light stimulusGO:00094161350.053
monocarboxylic acid metabolic processGO:00327871910.052
nucleobase containing small molecule metabolic processGO:00550863520.052
purine containing compound metabolic processGO:00725213110.052
cellular amine metabolic processGO:0044106440.050
response to oxidative stressGO:00069791230.050
Fly
negative regulation of immune system processGO:00026832090.050
cellular response to dna damage stimulusGO:00069742070.049
positive regulation of programmed cell deathGO:00430682180.048
transmembrane transportGO:00550854120.048
purine nucleotide metabolic processGO:00061633020.048
positive regulation of cell deathGO:00109422240.046
regulation of mapk cascadeGO:00434082480.044
macromolecule catabolic processGO:00090572810.044
myeloid cell homeostasisGO:00022621140.044
response to peptide hormoneGO:00434341270.044
ribose phosphate metabolic processGO:00196932910.044
aromatic compound catabolic processGO:00194392860.043
negative regulation of intracellular signal transductionGO:19025321670.042
regulation of cell cycleGO:00517262810.042
inflammatory responseGO:00069542440.042
negative regulation of cellular amine metabolic processGO:003323910.041
positive regulation of cellular amine metabolic processGO:003324050.041
regulation of apoptotic signaling pathwayGO:20012331970.040
protein catabolic processGO:00301632210.039
cytoplasmic transportGO:00164822340.039
regulation of defense responseGO:00313472330.039
mapk cascadeGO:00001652810.038
respiratory system developmentGO:00605411900.037
positive regulation of cellular amino acid metabolic processGO:004576430.036
regulation of cellular response to stressGO:00801351590.036
negative regulation of phosphorus metabolic processGO:00105631840.036
innate immune responseGO:00450871570.035
hexose transportGO:0008645560.035
organic cyclic compound catabolic processGO:19013612950.035
oxidation reduction processGO:00551143420.034
myeloid cell differentiationGO:00300992330.033
heterocycle catabolic processGO:00467002800.033
nucleotide metabolic processGO:00091173320.033
regulation of cytokine productionGO:00018172660.033
purine ribonucleotide metabolic processGO:00091502900.033
purine nucleotide catabolic processGO:00061952110.032
cellular response to peptideGO:1901653920.032
positive regulation of cellular catabolic processGO:00313311480.032
small gtpase mediated signal transductionGO:0007264970.032
multicellular organism growthGO:00352641610.032
mitotic cell cycleGO:00002781950.032
developmental maturationGO:00217001930.032
response to nutrient levelsGO:00316671090.032
cell type specific apoptotic processGO:00972852680.032
reactive oxygen species metabolic processGO:0072593840.032
blood circulationGO:00080151950.031
cytokine productionGO:00018163190.031
organic anion transportGO:00157111370.031
organophosphate catabolic processGO:00464342320.031
axonogenesisGO:00074092740.031
homeostasis of number of cellsGO:00488722100.030
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.030
purine nucleoside metabolic processGO:00422782410.030
microtubule based processGO:00070172360.030
chromatin organizationGO:00063252060.030
immune effector processGO:00022523210.030
ribonucleoside metabolic processGO:00091192450.030
regulation of response to woundingGO:19030341890.030
male gamete generationGO:00482322850.030
spermatogenesisGO:00072832840.030
negative regulation of apoptotic signaling pathwayGO:20012341040.029
brown fat cell differentiationGO:0050873360.029
cellular homeostasisGO:00197252400.029
nitrogen compound transportGO:00717052710.029
glycosyl compound metabolic processGO:19016572460.029
negative regulation of cellular component organizationGO:00511291940.028
negative regulation of protein phosphorylationGO:00019331260.028
positive regulation of protein modification processGO:00314012990.028
ion transmembrane transportGO:00342203610.028
negative regulation of transferase activityGO:0051348850.028
regulation of cell growthGO:0001558910.028
regulation of inflammatory responseGO:00507271470.027
lymphocyte differentiationGO:00300982420.027
cellular macromolecule catabolic processGO:00442652060.027
leukocyte differentiationGO:00025213420.027
cellular protein complex assemblyGO:00436231160.027
neuron apoptotic processGO:00514021420.027
nucleoside phosphate catabolic processGO:19012922220.027
positive regulation of protein phosphorylationGO:00019342420.027
negative regulation of protein kinase activity by regulation of protein phosphorylationGO:004438720.027
membrane organizationGO:00610242450.026
cellular response to insulin stimulusGO:0032869780.026
response to organic cyclic compoundGO:00140701980.026
purine containing compound catabolic processGO:00725232130.025
glucose homeostasisGO:00425931280.025
regulation of cellular catabolic processGO:00313292420.025
regulation of neuron deathGO:19012141340.025
nucleoside metabolic processGO:00091162460.025
regulation of protein localizationGO:00328802310.024
g protein coupled receptor signaling pathwayGO:00071862430.024
purine ribonucleoside triphosphate metabolic processGO:00092052200.024
generation of precursor metabolites and energyGO:00060911030.024
organonitrogen compound catabolic processGO:19015652640.024
canonical wnt signaling pathwayGO:00600701300.024
regulation of interleukin 8 productionGO:003267730.024
regulation of hydrolase activityGO:00513362460.024
cell adhesionGO:00071553290.024
l amino acid transportGO:0015807320.024
cellular nitrogen compound catabolic processGO:00442702800.024
regulation of ion transportGO:00432692150.024
carbohydrate homeostasisGO:00335001280.024
muscle tissue developmentGO:00605373080.024
neuron deathGO:00709971540.024
rho protein signal transductionGO:0007266320.024
protein modification by small protein conjugationGO:00324461870.024
myosin filament organizationGO:003103330.024
telencephalon developmentGO:00215371860.024
urogenital system developmentGO:00016552610.023
regulation of fat cell differentiationGO:0045598810.023
microtubule cytoskeleton organizationGO:00002261570.023
dephosphorylationGO:00163111290.023
sensory perceptionGO:00076002450.023
ossificationGO:00015032160.023
regulation of anatomical structure sizeGO:00900661780.023
protein ubiquitinationGO:00165671710.023
actin cytoskeleton organizationGO:00300362200.023
ribonucleoside triphosphate metabolic processGO:00091992200.023
regulation of cell projection organizationGO:00313442060.023
renal system developmentGO:00720012250.023
ras protein signal transductionGO:0007265770.023
lipid biosynthetic processGO:00086101790.022
regulation of hormone levelsGO:00108172110.022
locomotory behaviorGO:00076261950.022
p38mapk cascadeGO:003806640.022
myosin filament assemblyGO:003103420.022
nucleoside phosphate metabolic processGO:00067533380.022
response to lipopolysaccharideGO:00324961280.022
ribonucleotide metabolic processGO:00092592910.022
erythrocyte differentiationGO:0030218880.022
response to molecule of bacterial originGO:00022371430.022
regulation of secretion by cellGO:19035302490.022
positive regulation of cell developmentGO:00107202370.022
macromolecule methylationGO:00434141200.021
intracellular protein transportGO:00068862040.021
response to inorganic substanceGO:0010035960.021
nucleoside triphosphate metabolic processGO:00091412300.021
production of molecular mediator involved in inflammatory responseGO:0002532210.021
monosaccharide transportGO:0015749580.021
purine ribonucleoside metabolic processGO:00461282410.021
interleukin 8 productionGO:003263740.021
regulation of cellular component biogenesisGO:00440871810.021
central nervous system neuron differentiationGO:00219531620.021
nucleotide catabolic processGO:00091662170.021
rna interferenceGO:001624620.021
apoptotic mitochondrial changesGO:0008637480.021
cellular response to peptide hormone stimulusGO:0071375920.021
respiratory tube developmentGO:00303231670.021
mitochondrion organizationGO:00070051340.020
lung developmentGO:00303241640.020
negative regulation of kinase activityGO:0033673810.020
asymmetric stem cell divisionGO:009872230.020
regulation of cell motilityGO:20001452360.020
blood vessel morphogenesisGO:00485142850.020
purine ribonucleoside triphosphate catabolic processGO:00092071990.020
muscle system processGO:00030121410.020
regulation of neuron differentiationGO:00456642810.020
amino acid transportGO:0006865610.020
cell growthGO:00160491300.020
organelle localizationGO:00516401790.020
camera type eye developmentGO:00430102660.020
spermatid differentiationGO:00485151150.020
cation transmembrane transportGO:00986552660.020
organonitrogen compound biosynthetic processGO:19015661920.020
purine ribonucleoside catabolic processGO:00461302050.019
polysaccharide metabolic processGO:0005976390.019
angiogenesisGO:00015252010.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
synaptic transmissionGO:00072683290.019
regulation of leukocyte differentiationGO:19021051590.019
purine nucleoside triphosphate catabolic processGO:00091462030.019
carbohydrate derivative biosynthetic processGO:19011371830.019
lipid localizationGO:00108761260.019
chromatin modificationGO:00165681870.019
endomembrane system organizationGO:00102561470.019
response to extracellular stimulusGO:00099911270.019
forebrain developmentGO:00309003020.019
nuclear transportGO:00511691390.019
regulation of kinase activityGO:00435492490.019
t cell activationGO:00421102890.019
purine ribonucleotide catabolic processGO:00091542080.019
carbohydrate derivative catabolic processGO:19011362310.018
b cell activationGO:00421131610.018
cellular response to oxidative stressGO:0034599760.018
endocytosisGO:00068971680.018
activation of mapkkk activityGO:000018510.018
positive regulation of nuclear transcribed mrna poly a tail shorteningGO:006021340.018
cellular response to hormone stimulusGO:00328701500.018
protein maturationGO:00516041760.018
positive regulation of growthGO:00459271040.018
regulation of metal ion transportGO:00109591060.018
circulatory system processGO:00030131970.018
organelle fissionGO:00482851700.018
monosaccharide metabolic processGO:00059961060.018
glycosyl compound catabolic processGO:19016582060.018
organophosphate biosynthetic processGO:00904071220.018
gliogenesisGO:00420631410.018
regulation of nucleotide metabolic processGO:00061401690.018
dendrite developmentGO:00163581150.018
nucleocytoplasmic transportGO:00069131390.018
cellular response to organic cyclic compoundGO:0071407870.018
carboxylic acid biosynthetic processGO:0046394860.018
ribonucleoside triphosphate catabolic processGO:00092031990.018
regulation of secretionGO:00510462740.018
protein modification by small protein conjugation or removalGO:00706472070.018
regulation of circadian sleep wake cycleGO:004274930.018
glucose metabolic processGO:0006006920.017
signal transduction by p53 class mediatorGO:0072331510.017
lipid transportGO:0006869980.017
adaptive immune responseGO:00022501550.017
intrinsic apoptotic signaling pathwayGO:00971931320.017
neural precursor cell proliferationGO:00613511210.017
negative regulation of organelle organizationGO:0010639900.017
organic hydroxy compound metabolic processGO:19016152030.017
response to reactive oxygen speciesGO:0000302560.017
maintenance of locationGO:0051235890.017
positive regulation of nervous system developmentGO:00519622210.017
regulation of reactive oxygen species metabolic processGO:2000377400.017
purine nucleoside catabolic processGO:00061522050.017
cytokine production involved in inflammatory responseGO:000253490.017
regulation of nuclear transcribed mrna poly a tail shorteningGO:006021140.016
l glutamate import into cellGO:199012330.016
regionalizationGO:00030023370.016
Zebrafish
regulation of membrane potentialGO:00423911920.016
alpha amino acid metabolic processGO:1901605590.016
regulation of stress activated mapk cascadeGO:0032872690.016
regulation of transferase activityGO:00513382630.016
regulation of lipid metabolic processGO:00192161180.016
regulation of protein kinase activityGO:00458592320.016
regulation of mitotic cell cycleGO:00073461260.016
regulation of neuron apoptotic processGO:00435231220.016
carbohydrate transportGO:0008643620.016
cellular carbohydrate metabolic processGO:00442621190.016
positive regulation of cytokine productionGO:00018191740.016
cell divisionGO:00513011200.016
cell maturationGO:00484691270.016
fatty acid metabolic processGO:00066311210.016
glycogen metabolic processGO:0005977320.016
multicellular organismal signalingGO:0035637910.016
small molecule biosynthetic processGO:00442831320.016
dna metabolic processGO:00062593030.016
kidney developmentGO:00018222130.016
striated muscle tissue developmentGO:00147062930.016
positive regulation of neuron differentiationGO:00456661410.015
glucan metabolic processGO:0044042320.015
negative regulation of cell motilityGO:2000146610.015
regulation of cell activationGO:00508652890.015
regulation of proteolysisGO:00301621640.015
regulation of circadian sleep wake cycle sleepGO:004518730.015
regulation of cell morphogenesis involved in differentiationGO:00107691510.015
peptide transportGO:00158331330.015
negative regulation of cell growthGO:0030308440.015
limb morphogenesisGO:00351081490.015
single organism nuclear importGO:1902593950.015
regulation of lymphocyte activationGO:00512492400.015
protein processingGO:00164851630.015
organic acid biosynthetic processGO:0016053860.015
methylationGO:00322591340.015
skeletal muscle organ developmentGO:00605381630.015
ribonucleoside catabolic processGO:00424542060.015
amide transportGO:00428861380.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
cellular response to cytokine stimulusGO:00713451890.015
nucleoside catabolic processGO:00091642060.015
neural tube developmentGO:00219151600.015
negative regulation of neuron apoptotic processGO:0043524920.015
positive regulation of purine nucleotide metabolic processGO:19005441140.015
protein localization to organelleGO:00333651850.015
ribonucleotide catabolic processGO:00092612080.015
negative regulation of neuron deathGO:1901215980.015
negative regulation of respiratory burst involved in inflammatory responseGO:006026610.015
cellular protein catabolic processGO:00442571550.015
negative regulation of cell developmentGO:00107211690.015
hexose metabolic processGO:0019318980.015
dna repairGO:00062811070.015
hormone secretionGO:00468791280.015
stress activated mapk cascadeGO:0051403800.015
cellular chemical homeostasisGO:00550822150.015
monosaccharide biosynthetic processGO:0046364440.014
regulation of synaptic growth at neuromuscular junctionGO:000858240.014
posttranscriptional regulation of gene expressionGO:00106081550.014
male genitalia morphogenesisGO:004880840.014
neurotransmitter transportGO:0006836760.014
modification dependent macromolecule catabolic processGO:00436321330.014
positive regulation of interleukin 8 productionGO:003275720.014
negative regulation of myeloid cell differentiationGO:0045638380.014
regulation of translationGO:0006417710.014
sodium ion transportGO:0006814730.014
negative regulation of mapk cascadeGO:0043409650.014
regulation of myeloid cell differentiationGO:0045637960.014
peptidyl lysine modificationGO:0018205770.014
i kappab kinase nf kappab signalingGO:0007249850.014
mitotic cell cycle processGO:19030471590.014
vesicle organizationGO:0016050600.014
peptide hormone secretionGO:00300721090.014
muscle cell differentiationGO:00426922610.014
epithelial tube morphogenesisGO:00605623030.014
glial cell differentiationGO:00100011310.014
nucleoside triphosphate catabolic processGO:00091432050.014
negative regulation of defense responseGO:0031348770.014
skin developmentGO:00435882200.014
gtp metabolic processGO:00460391440.014
male sex differentiationGO:00466611090.014
glucose transportGO:0015758560.014
development of primary sexual characteristicsGO:00451371430.014
regulation of respiratory burst involved in inflammatory responseGO:006026420.014
glycoprotein biosynthetic processGO:0009101890.014
peptide secretionGO:00027901140.014
gland developmentGO:00487323300.014
regulation of protein maturationGO:1903317960.014
multicellular organismal homeostasisGO:00488711640.014
amino acid import into cellGO:190283740.014
energy derivation by oxidation of organic compoundsGO:0015980770.013
regulation of glucose metabolic processGO:0010906600.013
placenta developmentGO:00018901400.013
chemotaxisGO:00069352470.013
hematopoietic progenitor cell differentiationGO:00022441430.013
stem cell developmentGO:00488642190.013
lateral inhibitionGO:004633110.013
kidney epithelium developmentGO:00720731210.013
response to acid chemicalGO:00011011110.013
regulation of purine nucleotide metabolic processGO:19005421690.013
modification dependent protein catabolic processGO:00199411330.013
monocarboxylic acid biosynthetic processGO:0072330610.013
regulation of system processGO:00440572000.013
response to starvationGO:0042594650.013
regulation of transmembrane transportGO:00347621280.013
cellular ion homeostasisGO:00068731650.013
reactive oxygen species biosynthetic processGO:190340980.013
germ cell developmentGO:00072811850.013
gtp catabolic processGO:00061841430.013
smoothened signaling pathwayGO:00072241050.013
negative regulation of cell cycleGO:00457861230.013
cation homeostasisGO:00550802120.013
regulation of cellular carbohydrate metabolic processGO:0010675750.013
regulation of cell migrationGO:00303342190.013
embryonic epithelial tube formationGO:00018381300.013
tube formationGO:00351481400.013
cellular response to lipidGO:00713961450.013
divalent metal ion transportGO:00708381720.013
morphogenesis of embryonic epitheliumGO:00163311590.013
regulation of protein catabolic processGO:00421761080.013
embryonic placenta developmentGO:0001892980.013
3 utr mediated mrna stabilizationGO:007093520.013
limbic system developmentGO:0021761720.013
multi multicellular organism processGO:00447061090.013
regulation of endopeptidase activityGO:0052548890.013
sensory perception of light stimulusGO:0050953540.013
covalent chromatin modificationGO:00165691630.013
epidermis developmentGO:00085441870.013
cellular response to inorganic substanceGO:0071241370.013
response to insulinGO:00328681000.013
regulation of peptide hormone secretionGO:0090276750.012
cellular glucan metabolic processGO:0006073320.012
compound eye developmentGO:004874910.012
detection of stimulusGO:0051606840.012
protein acylationGO:0043543640.012
positive regulation of defense responseGO:00313491240.012
single organism cell adhesionGO:00986021560.012
regulation of p38mapk cascadeGO:190074430.012
epithelial cell proliferationGO:00506731740.012
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.012
regulation of cell adhesionGO:00301551540.012
regulation of cell cycle processGO:00105641600.012
positive regulation of organelle organizationGO:00106381280.012
skeletal system developmentGO:00015013560.012
regulation of neural precursor cell proliferationGO:2000177700.012
sensory organ morphogenesisGO:00905962420.012
glycoprotein metabolic processGO:00091001160.012
second messenger mediated signalingGO:0019932730.012
protein hydroxylationGO:001812640.012
epithelial tube formationGO:00721751300.012
negative regulation of hydrolase activityGO:0051346710.012
ameboidal type cell migrationGO:00016671280.012
transmission of nerve impulseGO:0019226760.012
mrna metabolic processGO:0016071840.012
negative regulation of protein maturationGO:1903318790.012
neuron migrationGO:00017641220.012
cognitionGO:00508901490.012
extracellular matrix organizationGO:00301981470.012
amino acid uptake involved in synaptic transmissionGO:005193330.012
regulation of ossificationGO:00302781120.012
histone modificationGO:00165701590.012
negative regulation of growthGO:0045926990.012
Fly
organic hydroxy compound transportGO:0015850930.012
cellular response to nutrient levelsGO:0031669640.012
cardiac muscle contractionGO:0060048320.012
cardiac muscle hypertrophy in response to stressGO:0014898100.012
divalent inorganic cation transportGO:00725111780.012
germ line stem cell divisionGO:004207820.012
extracellular structure organizationGO:00430621480.012
regulation of establishment of protein localizationGO:00702011810.012
purine ribonucleoside monophosphate metabolic processGO:0009167800.012
hexose biosynthetic processGO:0019319390.012
b cell differentiationGO:0030183780.012
positive regulation of cellular component biogenesisGO:0044089940.012
vascular process in circulatory systemGO:0003018620.012
anion transmembrane transportGO:0098656710.012
midgut developmentGO:000749440.012
ubiquitin dependent protein catabolic processGO:00065111290.012
macromolecule deacylationGO:0098732370.012
response to oxygen levelsGO:0070482620.012
striated muscle contractionGO:0006941450.012
regulation of adaptive immune responseGO:0002819900.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
4 hydroxyproline metabolic processGO:001947150.012
pallium developmentGO:00215431200.012
retrograde transport endosome to golgiGO:004214720.012
meiotic cell cycleGO:00513211220.012
regulation of lymphocyte proliferationGO:00506701170.011
protein polymerizationGO:0051258570.011
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.011
cellular response to external stimulusGO:0071496880.011
immune response activating signal transductionGO:00027571160.011
muscle contractionGO:00069361010.011
organic hydroxy compound biosynthetic processGO:1901617770.011
protein localization to nucleusGO:00345041210.011
negative regulation of protein processingGO:0010955790.011
cerebral cortex developmentGO:0021987860.011
bone developmentGO:00603481200.011
male meiosis iGO:0007141160.011
neuronal action potentialGO:0019228540.011
regulation of carbohydrate metabolic processGO:0006109750.011
nuclear importGO:0051170950.011
morphogenesis of a branching structureGO:00017632030.011
organic acid transportGO:00158491010.011
regulation of homeostatic processGO:00328441820.011
detection of abiotic stimulusGO:0009582600.011
cellularizationGO:000734910.011
protein complex disassemblyGO:0043241400.011
cytokine mediated signaling pathwayGO:00192211150.011
meiotic nuclear divisionGO:00071261150.011
coenzyme metabolic processGO:0006732520.011
stem cell differentiationGO:00488632680.011
regulation of protein processingGO:0070613960.011
positive regulation of dna templated transcription elongationGO:003278620.011
sequestering of metal ionGO:0051238190.011
actin filament organizationGO:00070151130.011
nucleoside phosphate biosynthetic processGO:1901293790.011
regulation of blood vessel sizeGO:0050880560.011
cholesterol transportGO:0030301380.011
regulation of nucleoside metabolic processGO:00091181300.011
positive regulation of nucleoside metabolic processGO:0045979910.011
myotube differentiationGO:00149021050.011
regulation of body fluid levelsGO:00508781620.011
developmental growth involved in morphogenesisGO:00605601380.011
peptidyl serine modificationGO:0018209830.011
peptidyl tyrosine phosphorylationGO:00181081430.011
regulation of cell sizeGO:0008361720.011
alcohol metabolic processGO:00060661160.011
positive regulation of transcription from rna polymerase i promoterGO:004594330.011

Ddit4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
nervous system diseaseDOID:86300.038
immune system diseaseDOID:291400.030
hematopoietic system diseaseDOID:7400.022
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.015
organ system cancerDOID:005068600.015
primary immunodeficiency diseaseDOID:61200.013
disease of metabolismDOID:001466700.012
musculoskeletal system diseaseDOID:1700.012
brain diseaseDOID:93600.012
central nervous system diseaseDOID:33100.012