| spindle assembly involved in mitosis | GO:0090307 | 4 | 0.942 | Fly |
| binding of sperm to zona pellucida | GO:0007339 | 34 | 0.769 | |
| sperm egg recognition | GO:0035036 | 37 | 0.697 | |
| cell cell recognition | GO:0009988 | 44 | 0.617 | |
| microtubule cytoskeleton organization involved in mitosis | GO:1902850 | 4 | 0.517 | Fly |
| toxin transport | GO:1901998 | 38 | 0.237 | |
| rna splicing | GO:0008380 | 54 | 0.235 | |
| protein folding | GO:0006457 | 28 | 0.231 | Yeast |
| single fertilization | GO:0007338 | 82 | 0.226 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.173 | |
| protein refolding | GO:0042026 | 1 | 0.169 | |
| cell recognition | GO:0008037 | 83 | 0.156 | |
| protein import into nucleus | GO:0006606 | 95 | 0.145 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.140 | Fly |
| fertilization | GO:0009566 | 127 | 0.139 | |
| genitalia development | GO:0048806 | 37 | 0.122 | |
| spindle assembly | GO:0051225 | 13 | 0.122 | Fly |
| single organism nuclear import | GO:1902593 | 95 | 0.105 | |
| nuclear transport | GO:0051169 | 139 | 0.103 | |
| cytoplasmic microtubule organization | GO:0031122 | 14 | 0.101 | Fly |
| organelle assembly | GO:0070925 | 177 | 0.100 | Fly |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.099 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.098 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.084 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.084 | |
| regulation of exit from mitosis | GO:0007096 | 1 | 0.082 | |
| trna splicing via endonucleolytic cleavage and ligation | GO:0006388 | 1 | 0.081 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.080 | |
| microtubule based process | GO:0007017 | 236 | 0.075 | Fly |
| intracellular protein transport | GO:0006886 | 204 | 0.075 | |
| macromolecule methylation | GO:0043414 | 120 | 0.067 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.064 | |
| gonad development | GO:0008406 | 141 | 0.060 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.060 | |
| nuclear import | GO:0051170 | 95 | 0.059 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.059 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.058 | |
| muscle adaptation | GO:0043500 | 39 | 0.056 | |
| circulatory system process | GO:0003013 | 197 | 0.056 | |
| positive regulation of transcription from rna polymerase i promoter | GO:0045943 | 3 | 0.051 | |
| fibril organization | GO:0097435 | 2 | 0.050 | |
| mrna catabolic process | GO:0006402 | 22 | 0.049 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.048 | Fly |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.047 | |
| germ cell development | GO:0007281 | 185 | 0.046 | |
| regulation of protein stability | GO:0031647 | 52 | 0.045 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.045 | |
| organelle fission | GO:0048285 | 170 | 0.045 | Fly |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.044 | |
| muscle tissue development | GO:0060537 | 308 | 0.043 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.043 | |
| protein targeting | GO:0006605 | 143 | 0.042 | |
| chemotaxis | GO:0006935 | 247 | 0.041 | |
| dna replication | GO:0006260 | 52 | 0.040 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.040 | |
| protein import | GO:0017038 | 101 | 0.040 | |
| blood circulation | GO:0008015 | 195 | 0.040 | |
| female gamete generation | GO:0007292 | 74 | 0.039 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.038 | |
| rna localization | GO:0006403 | 23 | 0.038 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.037 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.037 | |
| negative regulation of growth | GO:0045926 | 99 | 0.037 | |
| chromatin organization | GO:0006325 | 206 | 0.036 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.035 | |
| cell fate commitment | GO:0045165 | 210 | 0.035 | |
| regulation of heart contraction | GO:0008016 | 77 | 0.035 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.035 | |
| protein localization to chromatin | GO:0071168 | 3 | 0.034 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.034 | |
| microtubule organizing center organization | GO:0031023 | 28 | 0.034 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.033 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.033 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.033 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.033 | |
| rna processing | GO:0006396 | 105 | 0.032 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.032 | |
| rna splicing via endonucleolytic cleavage and ligation | GO:0000394 | 1 | 0.032 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.032 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.030 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.030 | |
| heart process | GO:0003015 | 94 | 0.030 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.029 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.029 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.029 | Fly |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.029 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 83 | 0.028 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.028 | |
| muscle system process | GO:0003012 | 141 | 0.028 | |
| protein localization to organelle | GO:0033365 | 185 | 0.027 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.027 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.027 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.027 | |
| camera type eye development | GO:0043010 | 266 | 0.027 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.027 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.026 | |
| regulation of metal ion transport | GO:0010959 | 106 | 0.026 | |
| oocyte construction | GO:0007308 | 2 | 0.026 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.026 | |
| regulation of muscle system process | GO:0090257 | 80 | 0.026 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.026 | |
| positive regulation of ion transmembrane transport | GO:0034767 | 24 | 0.025 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.025 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 57 | 0.025 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.025 | |
| regulation of striated muscle cell differentiation | GO:0051153 | 81 | 0.025 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.025 | |
| transmembrane transport | GO:0055085 | 412 | 0.025 | |
| pore complex assembly | GO:0046931 | 3 | 0.024 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.024 | |
| histone acetylation | GO:0016573 | 41 | 0.024 | |
| regulation of blood circulation | GO:1903522 | 93 | 0.024 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.024 | |
| oocyte anterior posterior axis specification | GO:0007314 | 2 | 0.024 | |
| lamellipodium organization | GO:0097581 | 29 | 0.024 | |
| regulation of ion transport | GO:0043269 | 215 | 0.023 | |
| cognition | GO:0050890 | 149 | 0.023 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.023 | |
| membrane organization | GO:0061024 | 245 | 0.023 | |
| protein localization to nuclear envelope | GO:0090435 | 2 | 0.023 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.023 | |
| lateral inhibition | GO:0046331 | 1 | 0.023 | |
| regulation of protein localization | GO:0032880 | 231 | 0.023 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.023 | |
| rrna containing ribonucleoprotein complex export from nucleus | GO:0071428 | 1 | 0.022 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.022 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.022 | |
| heart contraction | GO:0060047 | 93 | 0.022 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.022 | Fly |
| leukocyte migration | GO:0050900 | 124 | 0.022 | |
| positive regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045899 | 2 | 0.022 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.022 | |
| multicellular organism growth | GO:0035264 | 161 | 0.022 | |
| protein stabilization | GO:0050821 | 25 | 0.021 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.021 | |
| nuclear transcribed mrna catabolic process nonsense mediated decay | GO:0000184 | 1 | 0.021 | |
| regulation of calcium ion transport | GO:0051924 | 69 | 0.021 | |
| nuclear transcribed mrna catabolic process | GO:0000956 | 16 | 0.021 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.021 | |
| amine metabolic process | GO:0009308 | 45 | 0.021 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.021 | |
| cell growth | GO:0016049 | 130 | 0.020 | |
| dna metabolic process | GO:0006259 | 303 | 0.020 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.020 | |
| endocytosis | GO:0006897 | 168 | 0.020 | Worm |
| regulation of cell growth | GO:0001558 | 91 | 0.020 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.019 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.019 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.019 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.019 | |
| dendrite development | GO:0016358 | 115 | 0.019 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.018 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.018 | |
| regulation of mrna processing | GO:0050684 | 41 | 0.018 | |
| mrna splicing via spliceosome | GO:0000398 | 43 | 0.018 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.018 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.018 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.017 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.017 | |
| positive regulation of growth | GO:0045927 | 104 | 0.017 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.017 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.017 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.017 | |
| carboxylic acid biosynthetic process | GO:0046394 | 86 | 0.017 | |
| protein methylation | GO:0006479 | 81 | 0.017 | |
| male gamete generation | GO:0048232 | 285 | 0.016 | |
| regulation of organ morphogenesis | GO:2000027 | 144 | 0.016 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.016 | |
| regulation of protein transport | GO:0051223 | 163 | 0.016 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.016 | |
| regulation of muscle adaptation | GO:0043502 | 31 | 0.016 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.016 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.016 | |
| positive regulation of nucleocytoplasmic transport | GO:0046824 | 30 | 0.016 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.016 | |
| chromatin modification | GO:0016568 | 187 | 0.016 | |
| small molecule biosynthetic process | GO:0044283 | 132 | 0.016 | |
| body morphogenesis | GO:0010171 | 45 | 0.016 | Worm |
| axonogenesis | GO:0007409 | 274 | 0.015 | |
| positive regulation of histone methylation | GO:0031062 | 16 | 0.015 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.015 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.015 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.015 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.015 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.015 | |
| response to inorganic substance | GO:0010035 | 96 | 0.015 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.014 | |
| mapk cascade | GO:0000165 | 281 | 0.014 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.014 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.014 | |
| regulation of cell activation | GO:0050865 | 289 | 0.014 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.014 | |
| regulation of transporter activity | GO:0032409 | 57 | 0.014 | |
| positive regulation of ion transport | GO:0043270 | 65 | 0.014 | |
| internal peptidyl lysine acetylation | GO:0018393 | 42 | 0.014 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.014 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.014 | |
| spermatid differentiation | GO:0048515 | 115 | 0.014 | |
| cellularization | GO:0007349 | 1 | 0.014 | |
| sperm individualization | GO:0007291 | 1 | 0.013 | |
| regulation of system process | GO:0044057 | 200 | 0.013 | |
| learning or memory | GO:0007611 | 148 | 0.013 | |
| positive regulation of protein complex assembly | GO:0031334 | 45 | 0.013 | |
| respiratory system development | GO:0060541 | 190 | 0.013 | |
| translation | GO:0006412 | 93 | 0.013 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.013 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.013 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.013 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.013 | |
| regulation of cell adhesion | GO:0030155 | 154 | 0.013 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.013 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.013 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.013 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.013 | |
| oogenesis | GO:0048477 | 56 | 0.013 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.012 | |
| regulation of mrna splicing via spliceosome | GO:0048024 | 32 | 0.012 | |
| organelle localization | GO:0051640 | 179 | 0.012 | |
| protein localization to membrane | GO:0072657 | 108 | 0.012 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.012 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.012 | |
| digestive system development | GO:0055123 | 200 | 0.012 | |
| protein export from nucleus | GO:0006611 | 20 | 0.012 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.012 | |
| jnk cascade | GO:0007254 | 72 | 0.012 | |
| organic acid biosynthetic process | GO:0016053 | 86 | 0.012 | |
| detection of abiotic stimulus | GO:0009582 | 60 | 0.012 | |
| regulation of rna splicing | GO:0043484 | 37 | 0.012 | |
| positive regulation of cardiac muscle contraction | GO:0060452 | 2 | 0.012 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.012 | |
| protein maturation | GO:0051604 | 176 | 0.012 | |
| nuclear division | GO:0000280 | 158 | 0.012 | Fly |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.012 | |
| polyamine transmembrane transport | GO:1902047 | 5 | 0.012 | |
| regulation of dna replication | GO:0006275 | 17 | 0.012 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.012 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.011 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.011 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.011 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.011 | |
| gtp metabolic process | GO:0046039 | 144 | 0.011 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.011 | |
| wound healing | GO:0042060 | 157 | 0.011 | |
| gliogenesis | GO:0042063 | 141 | 0.011 | |
| ribonucleoprotein complex localization | GO:0071166 | 1 | 0.011 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.011 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.011 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 112 | 0.011 | |
| vesicle uncoating | GO:0072319 | 4 | 0.011 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.011 | |
| dna templated transcription termination | GO:0006353 | 4 | 0.011 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 62 | 0.010 | |
| histone modification | GO:0016570 | 159 | 0.010 | |
| chaperone mediated protein folding | GO:0061077 | 10 | 0.010 | |
| maintenance of location | GO:0051235 | 89 | 0.010 | |
| oocyte development | GO:0048599 | 33 | 0.010 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.010 | |
| peptidyl lysine acetylation | GO:0018394 | 45 | 0.010 | |
| lipid localization | GO:0010876 | 126 | 0.010 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.010 | |
| regulation of striated muscle contraction | GO:0006942 | 25 | 0.010 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.010 | |