Mus musculus

60 known processes

Mat2a

methionine adenosyltransferase II, alpha

(Aliases: D630045P18Rik,MGC6545)

Mat2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.540
rna processingGO:00063961050.410
rna splicing via transesterification reactionsGO:0000375430.388
mrna splicing via spliceosomeGO:0000398430.384
rna splicingGO:0008380540.357
ribonucleoprotein complex subunit organizationGO:0071826280.188
mrna processingGO:0006397630.179
regulation of mrna metabolic processGO:1903311430.161
regulation of mrna splicing via spliceosomeGO:0048024320.137
organic cyclic compound catabolic processGO:19013612950.102
regulation of alternative mrna splicing via spliceosomeGO:000038180.092
regulation of mrna processingGO:0050684410.086
regulation of cell cycleGO:00517262810.083
transmembrane transportGO:00550854120.078
rna interferenceGO:001624620.075
mrna metabolic processGO:0016071840.072
alternative mrna splicing via spliceosomeGO:0000380120.070
apoptotic signaling pathwayGO:00971903060.064
posttranscriptional gene silencing by rnaGO:0035194100.061
nitrogen compound transportGO:00717052710.060
positive regulation of cell deathGO:00109422240.060
spliceosomal complex assemblyGO:000024560.060
posttranscriptional regulation of gene expressionGO:00106081550.059
cation transportGO:00068123990.055
macromolecule catabolic processGO:00090572810.053
negative regulation of molecular functionGO:00440922580.053
heterocycle catabolic processGO:00467002800.053
amine metabolic processGO:0009308450.052
regulation of rna splicingGO:0043484370.050
regulation of apoptotic signaling pathwayGO:20012331970.046
gene silencingGO:0016458380.044
cellular amine metabolic processGO:0044106440.044
mitochondrion organizationGO:00070051340.044
regulation of cell divisionGO:0051302760.043
cellular nitrogen compound catabolic processGO:00442702800.041
ribonucleoprotein complex disassemblyGO:003298830.040
positive regulation of apoptotic processGO:00430652170.039
organelle fissionGO:00482851700.038
regulation of androgen receptor signaling pathwayGO:006076530.037
regulation of cellular amino acid metabolic processGO:000652150.036
regulation of nuclear divisionGO:0051783560.036
cation transmembrane transportGO:00986552660.036
cellular amino acid metabolic processGO:00065201030.035
gonad developmentGO:00084061410.034
positive regulation of proteolysisGO:0045862850.034
purine containing compound metabolic processGO:00725213110.034
regulation of cellular response to stressGO:00801351590.034
protein complex disassemblyGO:0043241400.033
nucleoside metabolic processGO:00091162460.032
nucleoside phosphate metabolic processGO:00067533380.032
negative regulation of mrna processingGO:0050686120.032
posttranscriptional gene silencingGO:0016441100.032
protein refoldingGO:004202610.031
spermatogenesisGO:00072832840.031
small gtpase mediated signal transductionGO:0007264970.031
aromatic compound catabolic processGO:00194392860.030
positive regulation of programmed cell deathGO:00430682180.030
positive regulation of cellular amino acid metabolic processGO:004576430.030
positive regulation of intracellular estrogen receptor signaling pathwayGO:003314840.029
striated muscle tissue developmentGO:00147062930.029
cell type specific apoptotic processGO:00972852680.029
regulation of kinase activityGO:00435492490.029
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.029
regulation of muscle tissue developmentGO:1901861970.027
cytoplasmic transportGO:00164822340.027
inorganic ion transmembrane transportGO:00986602340.026
purine nucleotide metabolic processGO:00061633020.026
ion transmembrane transportGO:00342203610.026
regulation of ion transportGO:00432692150.026
blood circulationGO:00080151950.026
membrane organizationGO:00610242450.026
positive regulation of cellular catabolic processGO:00313311480.026
negative regulation of phosphorylationGO:00423261660.026
nucleocytoplasmic transportGO:00069131390.026
muscle tissue developmentGO:00605373080.025
ribonucleotide metabolic processGO:00092592910.025
oxidation reduction processGO:00551143420.025
negative regulation of phosphate metabolic processGO:00459361840.025
cellular homeostasisGO:00197252400.025
regulation of cellular amine metabolic processGO:0033238200.024
male gamete generationGO:00482322850.024
mitochondrial transportGO:0006839360.024
cellular ketone metabolic processGO:0042180840.024
protein modification by small protein conjugationGO:00324461870.024
wnt signaling pathwayGO:00160551880.024
androgen receptor signaling pathwayGO:003052180.024
development of primary sexual characteristicsGO:00451371430.024
nuclear divisionGO:00002801580.023
multicellular organism growthGO:00352641610.023
myosin filament organizationGO:003103330.023
muscle contractionGO:00069361010.023
negative regulation of phosphorus metabolic processGO:00105631840.023
angiogenesisGO:00015252010.023
glycosyl compound metabolic processGO:19016572460.023
regulation of transmembrane transportGO:00347621280.022
regulation of membrane potentialGO:00423911920.022
gene silencing by rnaGO:0031047190.022
morphogenesis of embryonic epitheliumGO:00163311590.022
organic acid biosynthetic processGO:0016053860.022
intracellular steroid hormone receptor signaling pathwayGO:0030518290.022
receptor biosynthetic processGO:003280030.022
divalent metal ion transportGO:00708381720.022
regulation of cell activationGO:00508652890.022
camera type eye developmentGO:00430102660.021
blood vessel morphogenesisGO:00485142850.021
circulatory system processGO:00030131970.021
positive regulation of dna templated transcription elongationGO:003278620.021
inorganic cation transmembrane transportGO:00986622070.021
regulation of cellular catabolic processGO:00313292420.021
regulation of transferase activityGO:00513382630.021
carboxylic acid biosynthetic processGO:0046394860.021
carbohydrate derivative biosynthetic processGO:19011371830.021
cellular lipid metabolic processGO:00442553230.020
oogenesisGO:0048477560.020
peptidyl amino acid modificationGO:00181933360.020
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.020
extrinsic apoptotic signaling pathwayGO:00971911260.019
ossificationGO:00015032160.019
ribonucleoside metabolic processGO:00091192450.019
organonitrogen compound catabolic processGO:19015652640.019
nuclear transportGO:00511691390.019
protein targetingGO:00066051430.019
nucleobase containing small molecule metabolic processGO:00550863520.019
cellular chemical homeostasisGO:00550822150.019
purine ribonucleotide metabolic processGO:00091502900.019
regulation of meiotic cell cycleGO:0051445340.019
macromolecular complex disassemblyGO:0032984430.018
cellular macromolecule catabolic processGO:00442652060.018
carbohydrate homeostasisGO:00335001280.018
negative regulation of cell proliferationGO:00082852960.018
protein modification by small protein conjugation or removalGO:00706472070.018
nucleotide catabolic processGO:00091662170.018
divalent inorganic cation transportGO:00725111780.018
establishment of rna localizationGO:0051236180.018
germ cell developmentGO:00072811850.018
regulation of bindingGO:00510981110.018
sequestering of metal ionGO:0051238190.018
regulation of organelle organizationGO:00330432890.018
negative regulation of protein modification processGO:00314001630.018
skeletal muscle cell differentiationGO:0035914660.018
regulation of hydrolase activityGO:00513362460.017
sensory perceptionGO:00076002450.017
regulation of metal ion transportGO:00109591060.017
muscle cell differentiationGO:00426922610.017
glucose homeostasisGO:00425931280.017
immune effector processGO:00022523210.017
mitotic nuclear divisionGO:0007067480.017
regulation of protein complex disassemblyGO:0043244280.017
stem cell differentiationGO:00488632680.017
cell divisionGO:00513011200.017
fertilizationGO:00095661270.016
positive regulation of transcription from rna polymerase i promoterGO:004594330.016
purine containing compound catabolic processGO:00725232130.016
negative regulation of cell developmentGO:00107211690.016
regulation of ion transmembrane transportGO:00347651190.016
transmission of nerve impulseGO:0019226760.016
nucleoside phosphate catabolic processGO:19012922220.016
multicellular organismal homeostasisGO:00488711640.016
regulation of cell cycle processGO:00105641600.016
b cell activationGO:00421131610.016
calcium ion transportGO:00068161590.016
regulation of protein serine threonine kinase activityGO:00719001570.016
purine nucleotide catabolic processGO:00061952110.016
intrinsic apoptotic signaling pathwayGO:00971931320.015
actin cytoskeleton organizationGO:00300362200.015
multicellular organismal signalingGO:0035637910.015
purine ribonucleoside triphosphate metabolic processGO:00092052200.015
organonitrogen compound biosynthetic processGO:19015661920.015
negative regulation of cellular component organizationGO:00511291940.015
positive regulation of apoptotic signaling pathwayGO:2001235950.015
regulation of hormone levelsGO:00108172110.015
endocytosisGO:00068971680.015
cell adhesionGO:00071553290.015
ribose phosphate metabolic processGO:00196932910.015
regulation of protein kinase activityGO:00458592320.015
signal transduction by p53 class mediatorGO:0072331510.015
lipid transportGO:0006869980.015
regulation of cell cycle checkpointGO:190197690.015
regulation of response to woundingGO:19030341890.015
negative regulation of mrna splicing via spliceosomeGO:0048025120.014
ras protein signal transductionGO:0007265770.014
sperm motilityGO:0030317470.014
action potentialGO:0001508780.014
regulation of exit from mitosisGO:000709610.014
inflammatory responseGO:00069542440.014
embryonic limb morphogenesisGO:00303261260.014
regulation of cell adhesionGO:00301551540.014
myosin filament assemblyGO:003103420.014
glycosyl compound catabolic processGO:19016582060.014
tissue homeostasisGO:00018941150.014
organophosphate catabolic processGO:00464342320.014
protein catabolic processGO:00301632210.014
nucleobase containing compound transportGO:0015931270.014
protein targeting to mitochondrionGO:000662660.014
intracellular receptor signaling pathwayGO:0030522740.014
regulation of protein localizationGO:00328802310.013
purine ribonucleoside metabolic processGO:00461282410.013
respiratory system developmentGO:00605411900.013
negative regulation of intracellular signal transductionGO:19025321670.013
regulation of adaptive immune responseGO:0002819900.013
rho protein signal transductionGO:0007266320.013
sequestering of calcium ionGO:0051208180.013
regulation of cellular ketone metabolic processGO:0010565660.013
morphogenesis of a branching epitheliumGO:00611381930.013
negative regulation of transferase activityGO:0051348850.013
female gamete generationGO:0007292740.013
regulation of mapk cascadeGO:00434082480.013
heart processGO:0003015940.013
mitotic cell cycleGO:00002781950.013
skeletal system developmentGO:00015013560.013
meiotic nuclear divisionGO:00071261150.013
regulation of lymphocyte activationGO:00512492400.013
positive regulation of cellular amine metabolic processGO:003324050.013
cognitionGO:00508901490.013
nucleic acid transportGO:0050657180.013
purine nucleoside triphosphate metabolic processGO:00091442260.013
response to oxidative stressGO:00069791230.013
regulation of cell motilityGO:20001452360.013
regulation of ras protein signal transductionGO:00465781140.013
regulation of ossificationGO:00302781120.012
purine ribonucleoside triphosphate catabolic processGO:00092071990.012
negative regulation of adaptive immune responseGO:0002820250.012
anatomical structure homeostasisGO:00602491450.012
epithelial tube morphogenesisGO:00605623030.012
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018410.012
adaptive immune responseGO:00022501550.012
ribosome biogenesisGO:0042254200.012
mapk cascadeGO:00001652810.012
establishment of protein localization to organelleGO:00725941180.012
negative regulation of bindingGO:0051100390.012
actomyosin structure organizationGO:0031032560.012
positive regulation of growthGO:00459271040.012
stem cell developmentGO:00488642190.012
purine ribonucleotide catabolic processGO:00091542080.012
regulation of proteolysisGO:00301621640.012
trna wobble base modificationGO:000209720.012
symbiosis encompassing mutualism through parasitismGO:0044403830.012
intracellular protein transportGO:00068862040.012
circadian regulation of gene expressionGO:0032922480.012
calcium ion transmembrane transportGO:0070588850.012
negative regulation of rna splicingGO:0033119120.012
positive regulation of cysteine type endopeptidase activityGO:2001056390.012
hematopoietic progenitor cell differentiationGO:00022441430.012
single fertilizationGO:0007338820.012
muscle system processGO:00030121410.012
protein localization to nucleusGO:00345041210.012
cellular divalent inorganic cation homeostasisGO:00725031270.011
mrna splice site selectionGO:000637650.011
regionalizationGO:00030023370.011
heart contractionGO:0060047930.011
cell activation involved in immune responseGO:00022631260.011
spermatid differentiationGO:00485151150.011
striated muscle cell developmentGO:00550021250.011
dna metabolic processGO:00062593030.011
neuronal action potentialGO:0019228540.011
ear developmentGO:00435832000.011
striated muscle contractionGO:0006941450.011
cellular response to oxidative stressGO:0034599760.011
protein localization to organelleGO:00333651850.011
response to extracellular stimulusGO:00099911270.011
pharynx developmentGO:006046510.011
epidermis developmentGO:00085441870.011
negative regulation of kinase activityGO:0033673810.011
nucleoside triphosphate metabolic processGO:00091412300.011
epithelial cell proliferationGO:00506731740.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
regulation of lymphocyte mediated immunityGO:0002706840.011
regulation of wnt signaling pathwayGO:00301111230.011
rna catabolic processGO:0006401290.010
striated muscle myosin thick filament assemblyGO:007168810.010
circadian rhythmGO:00076231140.010
modification dependent macromolecule catabolic processGO:00436321330.010
regulation of transcription by chromatin organizationGO:003440100.010
cellular response to organonitrogen compoundGO:00714171450.010
ribonucleotide catabolic processGO:00092612080.010
monocarboxylic acid biosynthetic processGO:0072330610.010
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.010
lung developmentGO:00303241640.010
regulation of plasma lipoprotein particle levelsGO:0097006230.010
cellular potassium ion transportGO:0071804430.010
translationGO:0006412930.010
adult locomotory behaviorGO:0008344910.010
negative regulation of protein metabolic processGO:00512482820.010
regulation of epithelial cell proliferationGO:00506781410.010
skin developmentGO:00435882200.010
gland developmentGO:00487323300.010
regulation of purine nucleotide metabolic processGO:19005421690.010
cellular ion homeostasisGO:00068731650.010
cytokine productionGO:00018163190.010
regulation of dna damage checkpointGO:200000130.010
response to organonitrogen compoundGO:00102432460.010
adult behaviorGO:00305341350.010

Mat2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.036
disease of anatomical entityDOID:700.036
myopathyDOID:42300.036
muscular diseaseDOID:008000000.036
muscle tissue diseaseDOID:6600.036
nervous system diseaseDOID:86300.010