Mus musculus

92 known processes

C6

complement component 6

(Aliases: AW111623)

C6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense response to other organismGO:00985421970.133
Mouse
innate immune responseGO:00450871570.096
response to lipopolysaccharideGO:00324961280.082
cytokine productionGO:00018163190.079
regulation of leukocyte mediated immunityGO:00027031040.077
regulation of defense responseGO:00313472330.073
response to molecule of bacterial originGO:00022371430.071
regulation of inflammatory responseGO:00507271470.070
leukocyte mediated immunityGO:00024431740.070
immune effector processGO:00022523210.068
regulation of cell activationGO:00508652890.067
detection of fungusGO:001604620.065
regulation of lymphocyte activationGO:00512492400.064
regulation of cellular ketone metabolic processGO:0010565660.061
response to organonitrogen compoundGO:00102432460.059
regulation of cytokine productionGO:00018172660.058
regulation of protein maturationGO:1903317960.057
amine metabolic processGO:0009308450.056
cellular ketone metabolic processGO:0042180840.056
cellular amine metabolic processGO:0044106440.054
defense response to bacteriumGO:00427421190.051
carbohydrate derivative biosynthetic processGO:19011371830.050
regulation of establishment of protein localizationGO:00702011810.050
detection of yeastGO:000187920.049
positive regulation of cellular amino acid metabolic processGO:004576430.049
protein maturationGO:00516041760.048
positive regulation of cytokine productionGO:00018191740.047
regulation of cellular amino acid metabolic processGO:000652150.047
t cell activationGO:00421102890.047
regulation of cellular amine metabolic processGO:0033238200.047
positive regulation of defense responseGO:00313491240.045
regulation of lymphocyte mediated immunityGO:0002706840.045
aromatic compound catabolic processGO:00194392860.045
regulation of vesicle mediated transportGO:00606271390.044
peptidyl amino acid modificationGO:00181933360.044
regulation of protein localizationGO:00328802310.043
cellular response to organonitrogen compoundGO:00714171450.043
cell adhesionGO:00071553290.042
cellular response to molecule of bacterial originGO:0071219830.042
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.042
positive regulation of phagocytosisGO:0050766260.042
humoral immune responseGO:0006959570.041
macromolecule catabolic processGO:00090572810.040
negative regulation of immune system processGO:00026832090.039
carbohydrate metabolic processGO:00059752300.038
cellular response to lipopolysaccharideGO:0071222770.038
transmembrane transportGO:00550854120.037
Mouse
inflammatory responseGO:00069542440.037
positive regulation of cell deathGO:00109422240.036
Rat
lipid biosynthetic processGO:00086101790.036
cellular homeostasisGO:00197252400.036
cation transportGO:00068123990.036
i kappab kinase nf kappab signalingGO:0007249850.036
positive regulation of leukocyte mediated immunityGO:0002705700.035
regulation of hydrolase activityGO:00513362460.035
regulation of endocytosisGO:0030100690.035
cellular response to biotic stimulusGO:0071216920.035
regulation of t cell proliferationGO:0042129920.034
organic cyclic compound catabolic processGO:19013612950.034
positive regulation of cellular amine metabolic processGO:003324050.034
production of molecular mediator of immune responseGO:00024401030.034
cellular lipid metabolic processGO:00442553230.034
endocytosisGO:00068971680.034
regulation of secretionGO:00510462740.034
positive regulation of protein phosphorylationGO:00019342420.033
negative regulation of protein metabolic processGO:00512482820.033
regulation of t cell activationGO:00508631700.033
negative regulation of cell activationGO:00508661110.032
activation of immune responseGO:00022531380.032
cellular amino acid metabolic processGO:00065201030.032
negative regulation of molecular functionGO:00440922580.031
regulation of protein processingGO:0070613960.031
regulation of innate immune responseGO:0045088910.031
positive regulation of endocytosisGO:0045807420.031
purine nucleotide metabolic processGO:00061633020.030
regulation of intracellular transportGO:00323861590.030
macromolecule glycosylationGO:0043413550.030
sequestering of calcium ionGO:0051208180.030
positive regulation of lymphocyte mediated immunityGO:0002708620.029
reactive oxygen species metabolic processGO:0072593840.029
peptidyl tyrosine modificationGO:00182121450.029
regulation of leukocyte proliferationGO:00706631210.029
negative regulation of cellular protein metabolic processGO:00322692470.028
glycoprotein metabolic processGO:00091001160.028
mapk cascadeGO:00001652810.027
divalent inorganic cation homeostasisGO:00725071380.027
lymphocyte mediated immunityGO:00024491390.027
nucleotide catabolic processGO:00091662170.026
protein modification by small protein conjugation or removalGO:00706472070.026
carboxylic acid biosynthetic processGO:0046394860.026
cellular macromolecule catabolic processGO:00442652060.026
ras protein signal transductionGO:0007265770.026
positive regulation of reactive oxygen species biosynthetic processGO:190342820.026
small molecule biosynthetic processGO:00442831320.025
glycoprotein biosynthetic processGO:0009101890.025
ion transmembrane transportGO:00342203610.025
negative regulation of protein processingGO:0010955790.025
membrane organizationGO:00610242450.025
g protein coupled receptor signaling pathwayGO:00071862430.024
maintenance of locationGO:0051235890.024
regulation of adaptive immune responseGO:0002819900.024
positive regulation of protein modification processGO:00314012990.024
alcohol metabolic processGO:00060661160.024
regulation of protein transportGO:00512231630.024
sequestering of metal ionGO:0051238190.024
protein ubiquitinationGO:00165671710.024
purine ribonucleotide metabolic processGO:00091502900.024
nucleoside phosphate metabolic processGO:00067533380.023
protein processingGO:00164851630.023
cellular response to cytokine stimulusGO:00713451890.023
heterocycle catabolic processGO:00467002800.023
small gtpase mediated signal transductionGO:0007264970.023
homeostasis of number of cellsGO:00488722100.023
negative regulation of cell proliferationGO:00082852960.023
organic acid biosynthetic processGO:0016053860.023
nucleobase containing small molecule metabolic processGO:00550863520.023
regulation of proteolysisGO:00301621640.023
leukocyte differentiationGO:00025213420.023
positive regulation of activation of membrane attack complexGO:000197020.023
positive regulation of protein secretionGO:0050714520.023
nucleotide metabolic processGO:00091173320.023
nitrogen compound transportGO:00717052710.023
sterol metabolic processGO:0016125580.023
adaptive immune responseGO:00022501550.023
purine containing compound metabolic processGO:00725213110.022
myeloid cell differentiationGO:00300992330.022
regulation of blood pressureGO:0008217930.022
cytoplasmic transportGO:00164822340.022
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.022
positive regulation of secretionGO:00510471300.022
positive regulation of immune effector processGO:00026991070.022
cellular response to lipidGO:00713961450.022
sensory perceptionGO:00076002450.022
negative regulation of protein maturationGO:1903318790.022
positive regulation of protein transportGO:0051222930.022
muscle cell differentiationGO:00426922610.021
proteolysis involved in cellular protein catabolic processGO:00516031470.021
steroid metabolic processGO:00082021190.021
response to organic cyclic compoundGO:00140701980.021
negative regulation of proteolysisGO:0045861740.021
male gamete generationGO:00482322850.020
dna metabolic processGO:00062593030.020
monocarboxylic acid metabolic processGO:00327871910.020
spermatogenesisGO:00072832840.020
t cell proliferationGO:00420981200.020
protein glycosylationGO:0006486550.020
positive regulation of reactive oxygen species metabolic processGO:2000379110.020
protein modification by small protein conjugationGO:00324461870.020
regulation of endopeptidase activityGO:0052548890.020
divalent inorganic cation transportGO:00725111780.019
regulation of cell migrationGO:00303342190.019
glycosylationGO:0070085620.019
positive regulation of insulin receptor signaling pathwayGO:004662840.019
leukocyte activation involved in immune responseGO:00023661260.019
regulation of secretion by cellGO:19035302490.019
regulation of protein kinase activityGO:00458592320.019
negative regulation of endopeptidase activityGO:0010951440.019
metal ion homeostasisGO:00550651890.019
positive regulation of innate immune responseGO:0045089800.019
cytokine metabolic processGO:0042107710.019
positive regulation of adaptive immune responseGO:0002821610.019
reactive nitrogen species metabolic processGO:200105700.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
cell activation involved in immune responseGO:00022631260.018
wound healingGO:00420601570.018
regulation of response to woundingGO:19030341890.018
regulation of protein secretionGO:0050708820.018
hemostasisGO:0007599780.018
negative regulation of immune effector processGO:0002698550.018
rho protein signal transductionGO:0007266320.018
protein catabolic processGO:00301632210.018
regulation of ion transportGO:00432692150.018
immune response regulating signaling pathwayGO:00027641250.018
symbiosis encompassing mutualism through parasitismGO:0044403830.018
ribose phosphate metabolic processGO:00196932910.018
oxidation reduction processGO:00551143420.018
regulation of cellular catabolic processGO:00313292420.018
phagocytosisGO:0006909660.018
cellular nitrogen compound catabolic processGO:00442702800.018
alpha beta t cell activationGO:0046631910.018
nucleoside catabolic processGO:00091642060.017
lymphocyte proliferationGO:00466511640.017
cell chemotaxisGO:0060326810.017
nucleoside phosphate catabolic processGO:19012922220.017
regulation of reactive oxygen species biosynthetic processGO:190342620.017
interleukin 8 productionGO:003263740.017
positive regulation of secretion by cellGO:19035321140.017
regulation of mapk cascadeGO:00434082480.017
positive regulation of response to woundingGO:1903036660.017
regulation of cytokine biosynthetic processGO:0042035590.017
organelle localizationGO:00516401790.017
anatomical structure homeostasisGO:00602491450.017
negative regulation of lymphocyte proliferationGO:0050672450.017
response to acid chemicalGO:00011011110.017
cell killingGO:0001906670.016
regulation of cell cycleGO:00517262810.016
regulation of reactive oxygen species metabolic processGO:2000377400.016
divalent metal ion transportGO:00708381720.016
cellular metal ion homeostasisGO:00068751510.016
purine containing compound catabolic processGO:00725232130.016
immunoglobulin mediated immune responseGO:0016064690.016
regulation of lymphocyte proliferationGO:00506701170.016
response to molecule of fungal originGO:000223840.016
negative regulation of lymphocyte activationGO:0051250910.016
chemotaxisGO:00069352470.016
ribonucleotide metabolic processGO:00092592910.016
regulation of phospholipase a2 activityGO:003242930.016
lymphocyte differentiationGO:00300982420.016
cellular response to hormone stimulusGO:00328701500.016
purine ribonucleotide catabolic processGO:00091542080.016
purine nucleotide catabolic processGO:00061952110.015
angiogenesisGO:00015252010.015
carbohydrate derivative catabolic processGO:19011362310.015
regulation of cytoplasmic transportGO:19036491120.015
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.015
glycosyl compound metabolic processGO:19016572460.015
leukocyte proliferationGO:00706611720.015
regulation of system processGO:00440572000.015
positive regulation of apoptotic processGO:00430652170.015
Rat
ribonucleoside catabolic processGO:00424542060.015
protein secretionGO:00093061110.015
activation of innate immune responseGO:0002218560.015
positive regulation of cell activationGO:00508671580.015
regulation of peptidase activityGO:0052547960.015
purine nucleoside catabolic processGO:00061522050.014
single organismal cell cell adhesionGO:00163371310.014
negative regulation of peptidase activityGO:0010466460.014
multicellular organismal homeostasisGO:00488711640.014
purine nucleoside metabolic processGO:00422782410.014
extracellular matrix organizationGO:00301981470.014
blood coagulationGO:0007596760.014
purine nucleoside triphosphate catabolic processGO:00091462030.014
posttranscriptional regulation of gene expressionGO:00106081550.014
positive regulation of cytokine secretionGO:0050715410.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.014
organophosphate catabolic processGO:00464342320.014
response to peptide hormoneGO:00434341270.014
cation homeostasisGO:00550802120.014
positive regulation of programmed cell deathGO:00430682180.014
Rat
regulation of organelle organizationGO:00330432890.014
cytokine secretionGO:0050663720.014
glucuronate metabolic processGO:001958520.014
carbohydrate homeostasisGO:00335001280.014
regulation of interleukin 8 productionGO:003267730.014
organonitrogen compound catabolic processGO:19015652640.014
regulation of membrane potentialGO:00423911920.014
positive regulation of hydrolase activityGO:00513451480.014
calcium ion transportGO:00068161590.014
negative regulation of leukocyte proliferationGO:0070664460.014
regulation of cell motilityGO:20001452360.014
negative regulation of hydrolase activityGO:0051346710.014
regulation of monocyte chemotaxisGO:009002530.014
organic hydroxy compound metabolic processGO:19016152030.013
intracellular protein transportGO:00068862040.013
glucose homeostasisGO:00425931280.013
regulation of cell adhesionGO:00301551540.013
blood vessel morphogenesisGO:00485142850.013
apoptotic signaling pathwayGO:00971903060.013
calcium ion homeostasisGO:00550741270.013
ribonucleoside metabolic processGO:00091192450.013
regulation of body fluid levelsGO:00508781620.013
nucleoside triphosphate metabolic processGO:00091412300.013
cellular alcohol biosynthetic processGO:004410830.013
purine ribonucleoside metabolic processGO:00461282410.013
uronic acid metabolic processGO:000606320.013
regulation of immunoglobulin mediated immune responseGO:0002889370.013
negative regulation of multi organism processGO:0043901680.013
negative regulation of growthGO:0045926990.013
fatty acid metabolic processGO:00066311210.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
nucleoside metabolic processGO:00091162460.013
regulation of b cell mediated immunityGO:0002712370.013
interferon gamma productionGO:0032609670.013
cellular ion homeostasisGO:00068731650.013
cation transmembrane transportGO:00986552660.013
protein localization to organelleGO:00333651850.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.013
reactive oxygen species biosynthetic processGO:190340980.013
regulation of leukocyte differentiationGO:19021051590.013
monosaccharide metabolic processGO:00059961060.012
negative regulation of leukocyte mediated immunityGO:0002704290.012
ribonucleotide catabolic processGO:00092612080.012
exocytosisGO:00068871210.012
detection of other organismGO:009854380.012
response to growth factorGO:00708481980.012
negative regulation of intracellular signal transductionGO:19025321670.012
cytokine biosynthetic processGO:0042089680.012
regulation of striated muscle cell differentiationGO:0051153810.012
response to inorganic substanceGO:0010035960.012
cellular modified amino acid metabolic processGO:0006575630.012
immune response activating signal transductionGO:00027571160.012
positive regulation of intracellular transportGO:0032388700.012
regulation of interferon gamma productionGO:0032649570.012
compound eye developmentGO:004874910.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
skeletal system morphogenesisGO:00487052030.012
response to steroid hormoneGO:0048545560.012
cellular protein catabolic processGO:00442571550.012
cellular response to dna damage stimulusGO:00069742070.012
cellular chemical homeostasisGO:00550822150.012
cell divisionGO:00513011200.012
protein localization to nucleusGO:00345041210.012
regulation of protein catabolic processGO:00421761080.012
positive regulation of mapk cascadeGO:00434101700.012
regulation of transferase activityGO:00513382630.011
myotube differentiationGO:00149021050.011
negative regulation of t cell proliferationGO:0042130380.011
regulation of cytokine secretionGO:0050707610.011
inter male aggressive behaviorGO:000212130.011
rna interferenceGO:001624620.011
modification dependent protein catabolic processGO:00199411330.011
nuclear transportGO:00511691390.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
organonitrogen compound biosynthetic processGO:19015661920.011
naphthalene containing compound metabolic processGO:009042010.011
detection of stimulusGO:0051606840.011
cell type specific apoptotic processGO:00972852680.011
multicellular organism growthGO:00352641610.011
monocarboxylic acid biosynthetic processGO:0072330610.011
extracellular structure organizationGO:00430621480.011
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.011
regulation of hormone levelsGO:00108172110.011
antimicrobial peptide biosynthetic processGO:000277720.011
b cell mediated immunityGO:0019724710.011
regulation of multi organism processGO:00439001110.011
peptidyl tyrosine phosphorylationGO:00181081430.011
response to peptideGO:19016521360.011
antibacterial peptide biosynthetic processGO:000278020.011
mesodermal cell migrationGO:000807840.011
negative regulation of nik nf kappab signalingGO:190122320.011
ubiquitin dependent protein catabolic processGO:00065111290.011
leukocyte mediated cytotoxicityGO:0001909620.011
positive regulation of phospholipase activityGO:001051830.011
phosphatidylinositol mediated signalingGO:0048015410.011
negative regulation of t cell activationGO:0050868650.011
organelle fissionGO:00482851700.011
regulation of humoral immune responseGO:0002920220.011
activation of nf kappab inducing kinase activityGO:000725040.011
positive regulation of homeostatic processGO:0032846640.011
leukocyte migrationGO:00509001240.011
receptor mediated endocytosisGO:0006898510.011
dna repairGO:00062811070.011
synaptic transmissionGO:00072683290.011
nuclear divisionGO:00002801580.011
nucleoside triphosphate catabolic processGO:00091432050.011
interspecies interaction between organismsGO:0044419830.011
negative regulation of cellular response to growth factor stimulusGO:0090288460.010
regulation of nucleotide metabolic processGO:00061401690.010
positive regulation of cytoplasmic transportGO:1903651400.010
tissue homeostasisGO:00018941150.010
sulfur compound metabolic processGO:00067901000.010
regulation of cell cycle processGO:00105641600.010
single organism cell adhesionGO:00986021560.010
antimicrobial peptide productionGO:000277520.010
germ cell developmentGO:00072811850.010
interleukin 8 secretionGO:007260630.010
innate immune response activating cell surface receptor signaling pathwayGO:000222040.010
detection of external biotic stimulusGO:009858190.010
regulation of protein serine threonine kinase activityGO:00719001570.010
regulation of wound healingGO:0061041400.010
myeloid leukocyte differentiationGO:00025731190.010
regulation of map kinase activityGO:00434051200.010
striated muscle cell developmentGO:00550021250.010
secondary alcohol metabolic processGO:190265230.010
response to drugGO:0042493750.010
negative regulation of adaptive immune responseGO:0002820250.010

C6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.023
inherited metabolic disorderDOID:65500.023
anemiaDOID:235500.021
immune system diseaseDOID:291400.021
hemolytic anemiaDOID:58300.021
disease of anatomical entityDOID:700.021
normocytic anemiaDOID:72000.021
hemolytic uremic syndromeDOID:1255400.021
hematopoietic system diseaseDOID:7400.021
nervous system diseaseDOID:86300.016
sensory system diseaseDOID:005015500.011