Mus musculus

80 known processes

Ppt1

palmitoyl-protein thioesterase 1

(Aliases: MGC107420,AA960502,9530043G02Rik,C77813,CLN1,PPT,D4Ertd184e,INCL)

Ppt1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
peripheral nervous system axon regenerationGO:001401220.455
intermediate filament bundle assemblyGO:004511030.354
positive regulation of glial cell proliferationGO:006025240.314
microtubule based movementGO:0007018840.309
neurofilament cytoskeleton organizationGO:0060052100.308
microtubule based transportGO:0010970500.236
cytoskeleton dependent intracellular transportGO:0030705500.161
negative regulation of neuron deathGO:1901215980.148
cellular response to growth factor stimulusGO:00713631970.120
neuron apoptotic processGO:00514021420.109
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.108
schwann cell proliferationGO:001401020.103
intermediate filament based processGO:0045103270.098
axon cargo transportGO:0008088330.096
transmembrane transportGO:00550854120.096
regulation of schwann cell proliferationGO:001062420.096
negative regulation of cellular component organizationGO:00511291940.088
negative regulation of cell developmentGO:00107211690.085
negative regulation of cell projection organizationGO:0031345560.082
regulation of anatomical structure sizeGO:00900661780.077
cell type specific apoptotic processGO:00972852680.077
long term synaptic potentiationGO:0060291250.073
camera type eye developmentGO:00430102660.073
neuromuscular process controlling balanceGO:0050885590.070
cellular lipid metabolic processGO:00442553230.068
regulation of cellular component sizeGO:00325351210.066
regulation of neuron projection developmentGO:00109751690.066
Fly
response to vitamin dGO:003328030.066
neuromuscular processGO:0050905990.066
cellular amino acid metabolic processGO:00065201030.065
regulation of neuron apoptotic processGO:00435231220.064
positive regulation of neuron projection developmentGO:0010976790.062
neurotransmitter uptakeGO:0001504140.061
neurotransmitter transportGO:0006836760.060
negative regulation of neuron projection developmentGO:0010977500.060
macromolecule catabolic processGO:00090572810.059
negative regulation of protein metabolic processGO:00512482820.055
response to growth factorGO:00708481980.054
intermediate filament cytoskeleton organizationGO:0045104260.052
cellular ketone metabolic processGO:0042180840.051
regulation of neuron deathGO:19012141340.050
ion transmembrane transportGO:00342203610.049
glial cell differentiationGO:00100011310.048
regulation of neurotransmitter uptakeGO:005158060.048
cellular amine metabolic processGO:0044106440.047
amine metabolic processGO:0009308450.047
regulation of cell projection organizationGO:00313442060.046
Fly
negative regulation of neuron apoptotic processGO:0043524920.046
neuron projection regenerationGO:0031102140.045
membrane organizationGO:00610242450.045
negative regulation of nervous system developmentGO:00519611560.045
glial cell developmentGO:0021782540.045
positive regulation of neuron differentiationGO:00456661410.045
decidualizationGO:0046697100.044
positive regulation of cell projection organizationGO:0031346950.044
lytic vacuole organizationGO:0080171210.044
regulation of cellular amine metabolic processGO:0033238200.043
regulation of cell migrationGO:00303342190.040
regulation of cell morphogenesis involved in differentiationGO:00107691510.040
Fly
positive regulation of cellular amino acid metabolic processGO:004576430.040
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.039
extracellular matrix organizationGO:00301981470.039
cation transportGO:00068123990.039
regulation of neuron differentiationGO:00456642810.039
Fly
axonogenesisGO:00074092740.039
Fly
smad protein signal transductionGO:0060395210.038
regulation of synaptic plasticityGO:0048167870.038
fat cell differentiationGO:00454441600.038
positive regulation of cellular amine metabolic processGO:003324050.038
regulation of cellular amino acid metabolic processGO:000652150.037
cellular homeostasisGO:00197252400.037
peripheral nervous system neuron axonogenesisGO:004893630.037
dna metabolic processGO:00062593030.037
neuron deathGO:00709971540.037
positive regulation of cell developmentGO:00107202370.037
extracellular structure organizationGO:00430621480.037
positive regulation of gliogenesisGO:0014015270.036
nitrogen compound transportGO:00717052710.036
gliogenesisGO:00420631410.036
cation transmembrane transportGO:00986552660.035
response to organic cyclic compoundGO:00140701980.035
protein maturationGO:00516041760.034
positive regulation of schwann cell proliferationGO:001062510.034
cell adhesionGO:00071553290.033
protein catabolic processGO:00301632210.033
peptidyl amino acid modificationGO:00181933360.032
wound healingGO:00420601570.032
regulation of cellular ketone metabolic processGO:0010565660.032
sensory perceptionGO:00076002450.032
negative regulation of cellular protein metabolic processGO:00322692470.031
response to radiationGO:00093141650.031
inorganic ion transmembrane transportGO:00986602340.031
response to alcoholGO:0097305480.031
ras protein signal transductionGO:0007265770.030
protein modification by small protein conjugation or removalGO:00706472070.030
regulation of cytokine productionGO:00018172660.030
apoptotic signaling pathwayGO:00971903060.030
endomembrane system organizationGO:00102561470.030
regulation of cell projection sizeGO:003253660.030
regulation of transmembrane transportGO:00347621280.030
regulation of apoptotic signaling pathwayGO:20012331970.029
placenta developmentGO:00018901400.029
regulation of cell motilityGO:20001452360.028
negative regulation of molecular functionGO:00440922580.028
small gtpase mediated signal transductionGO:0007264970.027
carbohydrate derivative catabolic processGO:19011362310.027
cellular response to fibroblast growth factor stimulusGO:0044344470.027
regulation of mapk cascadeGO:00434082480.027
microtubule based processGO:00070172360.027
nuclear divisionGO:00002801580.027
reactive oxygen species metabolic processGO:0072593840.026
blood circulationGO:00080151950.026
regulation of gliogenesisGO:0014013500.026
astrocyte developmentGO:0014002120.026
regulation of transferase activityGO:00513382630.026
lens development in camera type eyeGO:0002088620.025
maternal process involved in female pregnancyGO:0060135320.025
cellular nitrogen compound catabolic processGO:00442702800.025
astrocyte differentiationGO:0048708430.025
peripheral nervous system developmentGO:0007422530.024
organic anion transportGO:00157111370.024
regulation of cell activationGO:00508652890.024
chemotaxisGO:00069352470.024
Fly
anion transportGO:00068201770.024
maternal placenta developmentGO:0001893200.024
interleukin 8 productionGO:003263740.024
heterocycle catabolic processGO:00467002800.024
epithelial cell developmentGO:00020641590.024
transforming growth factor beta receptor signaling pathwayGO:0007179710.023
cellular macromolecule catabolic processGO:00442652060.023
regulation of membrane potentialGO:00423911920.023
synaptic transmissionGO:00072683290.023
positive regulation of protein phosphorylationGO:00019342420.023
fertilizationGO:00095661270.023
monocarboxylic acid metabolic processGO:00327871910.023
regulation of neurotransmitter transportGO:0051588350.023
response to organonitrogen compoundGO:00102432460.022
regulation of protein transportGO:00512231630.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.022
phospholipid metabolic processGO:0006644870.022
regulation of kinase activityGO:00435492490.022
regulation of protein localizationGO:00328802310.022
organelle assemblyGO:00709251770.022
cellular ion homeostasisGO:00068731650.021
regulation of ion transmembrane transportGO:00347651190.020
membrane lipid metabolic processGO:0006643530.020
response to inorganic substanceGO:0010035960.020
negative regulation of phosphate metabolic processGO:00459361840.020
regulation of wnt signaling pathwayGO:00301111230.020
multicellular organismal signalingGO:0035637910.020
leukocyte activation involved in immune responseGO:00023661260.020
homeostasis of number of cellsGO:00488722100.020
organic hydroxy compound metabolic processGO:19016152030.020
nuclear transportGO:00511691390.019
circulatory system processGO:00030131970.019
response to peptideGO:19016521360.019
organic cyclic compound catabolic processGO:19013612950.019
inorganic cation transmembrane transportGO:00986622070.019
peptidyl tyrosine phosphorylationGO:00181081430.019
actin cytoskeleton organizationGO:00300362200.019
regulation of lymphocyte activationGO:00512492400.019
lipid localizationGO:00108761260.019
sphingolipid metabolic processGO:0006665450.018
purine ribonucleotide metabolic processGO:00091502900.018
canonical wnt signaling pathwayGO:00600701300.018
regulation of cellular response to stressGO:00801351590.018
cellular calcium ion homeostasisGO:00068741190.018
lysosome organizationGO:0007040210.018
regenerationGO:0031099380.018
protein localization to organelleGO:00333651850.018
skeletal muscle tissue regenerationGO:0043403200.018
blood coagulationGO:0007596760.018
regulation of system processGO:00440572000.018
response to transforming growth factor betaGO:0071559880.018
regulation of ion transportGO:00432692150.018
regulation of establishment of protein localizationGO:00702011810.018
regulation of intracellular transportGO:00323861590.018
cellular response to lipidGO:00713961450.018
regulation of reactive oxygen species biosynthetic processGO:190342620.018
maintenance of locationGO:0051235890.017
bergmann glial cell differentiationGO:006002060.017
vacuole organizationGO:0007033380.017
cellular chemical homeostasisGO:00550822150.017
carbohydrate metabolic processGO:00059752300.017
carboxylic acid transportGO:00469421000.017
innate immune responseGO:00450871570.017
regulation of ion transmembrane transporter activityGO:0032412540.017
male gamete generationGO:00482322850.017
divalent metal ion transportGO:00708381720.017
cell growthGO:00160491300.017
positive regulation of transferase activityGO:00513471670.017
gonad developmentGO:00084061410.017
carboxylic acid biosynthetic processGO:0046394860.017
negative regulation of intracellular signal transductionGO:19025321670.017
organonitrogen compound biosynthetic processGO:19015661920.017
peripheral nervous system neuron differentiationGO:004893490.017
positive regulation of kinase activityGO:00336741550.017
glycerolipid metabolic processGO:00464861220.017
negative regulation of phosphorus metabolic processGO:00105631840.017
positive regulation of nervous system developmentGO:00519622210.016
multi multicellular organism processGO:00447061090.016
cellular metal ion homeostasisGO:00068751510.016
rho protein signal transductionGO:0007266320.016
spermatogenesisGO:00072832840.016
negative regulation of wnt signaling pathwayGO:0030178730.016
nucleoside phosphate metabolic processGO:00067533380.016
reactive oxygen species biosynthetic processGO:190340980.016
regulation of voltage gated calcium channel activityGO:190138540.016
striated muscle tissue developmentGO:00147062930.016
cellular response to dna damage stimulusGO:00069742070.016
cellular response to transforming growth factor beta stimulusGO:0071560880.016
germ cell developmentGO:00072811850.016
ribonucleotide metabolic processGO:00092592910.016
cell activation involved in immune responseGO:00022631260.016
mapk cascadeGO:00001652810.016
calcium ion homeostasisGO:00550741270.016
glycerophospholipid metabolic processGO:0006650710.016
lipid biosynthetic processGO:00086101790.016
learning or memoryGO:00076111480.016
protein targetingGO:00066051430.016
signal transduction in absence of ligandGO:0038034550.016
second messenger mediated signalingGO:0019932730.016
reactive nitrogen species metabolic processGO:200105700.015
response to steroid hormoneGO:0048545560.015
aromatic compound catabolic processGO:00194392860.015
protein ubiquitinationGO:00165671710.015
negative regulation of protein modification processGO:00314001630.015
regulation of secretionGO:00510462740.015
lipid catabolic processGO:0016042690.015
response to extracellular stimulusGO:00099911270.015
leukocyte differentiationGO:00025213420.015
oxidation reduction processGO:00551143420.015
peptidyl tyrosine modificationGO:00182121450.015
regulation of organelle organizationGO:00330432890.015
b cell activationGO:00421131610.015
stem cell differentiationGO:00488632680.015
protein localization to membraneGO:00726571080.015
regulation of homeostatic processGO:00328441820.015
protein localization to plasma membraneGO:0072659570.015
regulation of response to woundingGO:19030341890.015
regulation of body fluid levelsGO:00508781620.015
wnt signaling pathwayGO:00160551880.015
multicellular organismal homeostasisGO:00488711640.015
spermatid developmentGO:00072861080.015
glycoprotein metabolic processGO:00091001160.014
muscle system processGO:00030121410.014
glycosyl compound metabolic processGO:19016572460.014
cell matrix adhesionGO:0007160680.014
leukocyte proliferationGO:00706611720.014
meiotic cell cycleGO:00513211220.014
neuronal action potentialGO:0019228540.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
axon regenerationGO:0031103120.014
cellular response to hormone stimulusGO:00328701500.014
protein modification by small protein conjugationGO:00324461870.014
cell chemotaxisGO:0060326810.014
cellular protein complex assemblyGO:00436231160.014
cellular lipid catabolic processGO:0044242520.014
regulation of reactive oxygen species metabolic processGO:2000377400.014
anatomical structure homeostasisGO:00602491450.014
i kappab kinase nf kappab signalingGO:0007249850.014
protein processingGO:00164851630.014
regulation of protein processingGO:0070613960.014
regulation of t cell activationGO:00508631700.014
response to nutrient levelsGO:00316671090.014
nucleobase containing small molecule metabolic processGO:00550863520.014
smoothened signaling pathwayGO:00072241050.014
purine containing compound metabolic processGO:00725213110.014
response to peptide hormoneGO:00434341270.013
negative regulation of cellular amine metabolic processGO:003323910.013
organelle fissionGO:00482851700.013
negative regulation of cytokine productionGO:0001818840.013
microglia differentiationGO:001400420.013
regulation of axon diameterGO:003113360.013
purinergic nucleotide receptor signaling pathwayGO:003559030.013
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.013
meiotic nuclear divisionGO:00071261150.013
cation homeostasisGO:00550802120.013
positive regulation of defense responseGO:00313491240.013
transmission of nerve impulseGO:0019226760.013
calcium ion transportGO:00068161590.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
response to oxidative stressGO:00069791230.013
regulation of systemic arterial blood pressureGO:0003073610.013
development of primary sexual characteristicsGO:00451371430.013
regulation of transporter activityGO:0032409570.013
negative regulation of protein phosphorylationGO:00019331260.013
cytokine productionGO:00018163190.013
skeletal system developmentGO:00015013560.013
ribose phosphate metabolic processGO:00196932910.013
cell recognitionGO:0008037830.013
endocytosisGO:00068971680.013
Fly
amide transportGO:00428861380.013
nucleocytoplasmic transportGO:00069131390.013
leukocyte chemotaxisGO:0030595690.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
regulation of cell growthGO:0001558910.013
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.013
cytoplasmic transportGO:00164822340.012
negative regulation of cell proliferationGO:00082852960.012
developmental growth involved in morphogenesisGO:00605601380.012
organelle localizationGO:00516401790.012
Fly
nucleotide metabolic processGO:00091173320.012
regulation of protein kinase activityGO:00458592320.012
regulation of metal ion transportGO:00109591060.012
intracellular protein transportGO:00068862040.012
ear developmentGO:00435832000.012
sulfur compound metabolic processGO:00067901000.012
monosaccharide metabolic processGO:00059961060.012
nucleoside catabolic processGO:00091642060.012
chromatin organizationGO:00063252060.012
nuclear importGO:0051170950.012
immune effector processGO:00022523210.012
l amino acid transportGO:0015807320.012
regulation of cellular catabolic processGO:00313292420.012
regulation of glial cell proliferationGO:006025180.012
angiogenesisGO:00015252010.012
skeletal muscle organ developmentGO:00605381630.012
hemostasisGO:0007599780.012
sequestering of metal ionGO:0051238190.012
small molecule biosynthetic processGO:00442831320.012
kidney developmentGO:00018222130.012
regulation of secretion by cellGO:19035302490.012
regulation of interleukin 8 productionGO:003267730.012
sensory organ morphogenesisGO:00905962420.012
fatty acid metabolic processGO:00066311210.012
establishment of protein localization to organelleGO:00725941180.012
spindle assembly involved in mitosisGO:009030740.012
cell cell recognitionGO:0009988440.012
regulation of cellular response to growth factor stimulusGO:0090287820.012
nucleoside triphosphate metabolic processGO:00091412300.012
transepithelial chloride transportGO:003032140.012
hematopoietic progenitor cell differentiationGO:00022441430.012
heart contractionGO:0060047930.012
glial cell migrationGO:000834770.012
ribonucleoside metabolic processGO:00091192450.012
compound eye developmentGO:004874910.012
single organismal cell cell adhesionGO:00163371310.012
ceramide metabolic processGO:0006672310.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
positive regulation of programmed cell deathGO:00430682180.011
urogenital system developmentGO:00016552610.011
plasma membrane organizationGO:0007009900.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
phosphatidylinositol metabolic processGO:0046488450.011
organophosphate catabolic processGO:00464342320.011
leukocyte migrationGO:00509001240.011
myeloid leukocyte differentiationGO:00025731190.011
dna repairGO:00062811070.011
regulation of protein serine threonine kinase activityGO:00719001570.011
positive regulation of apoptotic signaling pathwayGO:2001235950.011
positive regulation of cell adhesionGO:0045785800.011
response to lipopolysaccharideGO:00324961280.011
negative regulation of phosphorylationGO:00423261660.011
organonitrogen compound catabolic processGO:19015652640.011
peptidyl serine phosphorylationGO:0018105740.011
ameboidal type cell migrationGO:00016671280.011
regulation of cell cycleGO:00517262810.011
morphogenesis of a branching epitheliumGO:00611381930.011
intermediate filament organizationGO:0045109150.011
cognitionGO:00508901490.011
protein autophosphorylationGO:0046777610.011
protein oligomerizationGO:0051259670.011
lymphocyte differentiationGO:00300982420.011
lipid transportGO:0006869980.011
regulation of cytoplasmic transportGO:19036491120.011
response to oxygen levelsGO:0070482620.011
regulation of leukocyte mediated immunityGO:00027031040.011
positive regulation of interleukin 8 productionGO:003275720.011
regulation of cellular component biogenesisGO:00440871810.011
monovalent inorganic cation homeostasisGO:0055067330.011
anion transmembrane transportGO:0098656710.011
neuron migrationGO:00017641220.011
dephosphorylationGO:00163111290.011
small molecule catabolic processGO:0044282710.011
leukocyte mediated immunityGO:00024431740.011
purine nucleoside metabolic processGO:00422782410.011
inflammatory responseGO:00069542440.011
regulation of blood vessel sizeGO:0050880560.011
negative regulation of phagocytosisGO:005076540.011
regulation of nucleocytoplasmic transportGO:0046822730.010
regulation of protein catabolic processGO:00421761080.010
cellular response to lipopolysaccharideGO:0071222770.010
organic acid biosynthetic processGO:0016053860.010
ubiquitin dependent protein catabolic processGO:00065111290.010
sodium ion transportGO:0006814730.010
lipid modificationGO:0030258650.010
negative regulation of protein maturationGO:1903318790.010
gland developmentGO:00487323300.010
posttranscriptional regulation of gene expressionGO:00106081550.010
negative regulation of cellular response to growth factor stimulusGO:0090288460.010
alcohol metabolic processGO:00060661160.010
organ regenerationGO:003110020.010
cellular response to peptide hormone stimulusGO:0071375920.010
response to zinc ionGO:001004350.010
cofactor transportGO:005118140.010
inorganic anion transportGO:0015698430.010
positive regulation of reactive oxygen species metabolic processGO:2000379110.010
locomotory behaviorGO:00076261950.010
g protein coupled receptor signaling pathwayGO:00071862430.010

Ppt1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.062
nervous system diseaseDOID:86300.062
central nervous system diseaseDOID:33100.047
disease of metabolismDOID:001466700.045
inherited metabolic disorderDOID:65500.040
lysosomal storage diseaseDOID:321100.029
brain diseaseDOID:93600.028
eye and adnexa diseaseDOID:149200.021
sensory system diseaseDOID:005015500.021
eye diseaseDOID:561400.016
retinal degenerationDOID:846600.016
retinal diseaseDOID:567900.016
immune system diseaseDOID:291400.015
connective tissue diseaseDOID:6500.015
musculoskeletal system diseaseDOID:1700.015
bone diseaseDOID:008000100.015
cerebral degenerationDOID:144300.014