| phototransduction | GO:0007602 | 17 | 0.978 | Mouse |
| gtp catabolic process | GO:0006184 | 143 | 0.965 | |
| regulation of gtp catabolic process | GO:0033124 | 113 | 0.962 | |
| positive regulation of gtp catabolic process | GO:0033126 | 85 | 0.948 | |
| positive regulation of gtpase activity | GO:0043547 | 85 | 0.946 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.944 | |
| protein desumoylation | GO:0016926 | 2 | 0.943 | Fly |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.934 | |
| negative regulation of peptidyl tyrosine phosphorylation | GO:0050732 | 17 | 0.924 | Fly |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.921 | |
| g protein coupled receptor internalization | GO:0002031 | 3 | 0.914 | Human |
| nucleoside catabolic process | GO:0009164 | 206 | 0.909 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.906 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.893 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.892 | |
| negative regulation of transferase activity | GO:0051348 | 85 | 0.883 | Fly |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.873 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.872 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.871 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.864 | |
| regulation of interleukin 6 production | GO:0032675 | 55 | 0.861 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.861 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.859 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.854 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.848 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.840 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.839 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 88 | 0.837 | |
| negative regulation of kinase activity | GO:0033673 | 81 | 0.833 | Fly |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 88 | 0.833 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.826 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.826 | |
| negative regulation of toll signaling pathway | GO:0045751 | 1 | 0.818 | Fly |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.816 | |
| negative regulation of protein tyrosine kinase activity | GO:0061099 | 3 | 0.814 | Fly |
| rho protein signal transduction | GO:0007266 | 32 | 0.812 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.811 | Fly |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.805 | |
| gtp metabolic process | GO:0046039 | 144 | 0.799 | |
| negative regulation of interleukin 6 production | GO:0032715 | 17 | 0.789 | |
| mapk cascade | GO:0000165 | 281 | 0.786 | Human Mouse |
| amine metabolic process | GO:0009308 | 45 | 0.782 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.781 | Fly |
| negative regulation of interleukin 1 beta production | GO:0032691 | 5 | 0.778 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.777 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.773 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.773 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.770 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.763 | Fly |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.763 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.759 | |
| positive regulation of innate immune response | GO:0045089 | 80 | 0.736 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.733 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.732 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.730 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.729 | |
| desensitization of g protein coupled receptor protein signaling pathway | GO:0002029 | 5 | 0.729 | Human |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.726 | |
| regulation of peptidyl serine phosphorylation | GO:0033135 | 39 | 0.722 | Mouse |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.722 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.718 | |
| negative regulation of g protein coupled receptor protein signaling pathway | GO:0045744 | 12 | 0.713 | Human |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.712 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.711 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.710 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.710 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.706 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.705 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.705 | |
| actin filament organization | GO:0007015 | 113 | 0.703 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.694 | Mouse |
| toll like receptor signaling pathway | GO:0002224 | 38 | 0.681 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.678 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.672 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.670 | |
| regulation of toll signaling pathway | GO:0008592 | 1 | 0.665 | Fly |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.665 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.662 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.660 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.659 | |
| positive regulation of rho gtpase activity | GO:0032321 | 41 | 0.652 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.651 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.650 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.646 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.643 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.641 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.630 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.625 | |
| positive regulation of protein kinase b signaling | GO:0051897 | 32 | 0.619 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.619 | Fly |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.618 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.618 | Human |
| regulation of kinase activity | GO:0043549 | 249 | 0.611 | Fly |
| actin filament bundle assembly | GO:0051017 | 40 | 0.606 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.605 | Human |
| negative regulation of hydrolase activity | GO:0051346 | 71 | 0.604 | Mouse |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.602 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.600 | |
| regulation of ras gtpase activity | GO:0032318 | 88 | 0.590 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.572 | Human |
| regulation of actin filament length | GO:0030832 | 45 | 0.569 | |
| pattern recognition receptor signaling pathway | GO:0002221 | 47 | 0.565 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.562 | |
| negative regulation of defense response | GO:0031348 | 77 | 0.561 | Human Fly |
| activation of immune response | GO:0002253 | 138 | 0.553 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.549 | |
| interleukin 6 production | GO:0032635 | 58 | 0.547 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.533 | Human |
| response to radiation | GO:0009314 | 165 | 0.530 | Mouse |
| regulation of toll like receptor signaling pathway | GO:0034121 | 20 | 0.523 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.521 | Mouse Fly |
| peptidyl tyrosine phosphorylation | GO:0018108 | 143 | 0.514 | Fly |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.512 | Mouse |
| positive regulation of ras gtpase activity | GO:0032320 | 65 | 0.509 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.495 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.488 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.486 | Human |
| negative adaptation of signaling pathway | GO:0022401 | 5 | 0.485 | Human |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.485 | Human Mouse Fly |
| regulation of erk1 and erk2 cascade | GO:0070372 | 71 | 0.482 | Human Mouse |
| negative regulation of toll like receptor signaling pathway | GO:0034122 | 14 | 0.478 | |
| positive regulation of synaptic transmission dopaminergic | GO:0032226 | 5 | 0.473 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.473 | Human Fly |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.466 | Human Fly |
| positive regulation of receptor internalization | GO:0002092 | 4 | 0.465 | Human |
| innate immune response activating signal transduction | GO:0002758 | 50 | 0.463 | |
| regulation of protein tyrosine kinase activity | GO:0061097 | 17 | 0.456 | Fly |
| cytokine production | GO:0001816 | 319 | 0.446 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.444 | Mouse |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.437 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.430 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.430 | Mouse |
| erk1 and erk2 cascade | GO:0070371 | 77 | 0.426 | Human Mouse |
| regulation of proteolysis | GO:0030162 | 164 | 0.425 | Mouse |
| adult walking behavior | GO:0007628 | 41 | 0.422 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.421 | Human |
| negative regulation of inflammatory response | GO:0050728 | 61 | 0.414 | Fly |
| protein modification by small protein removal | GO:0070646 | 21 | 0.409 | Fly |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.408 | Human Mouse Fly |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.387 | |
| negative regulation of response to wounding | GO:1903035 | 77 | 0.386 | Fly |
| regulation of cytokine production | GO:0001817 | 266 | 0.380 | |
| organelle assembly | GO:0070925 | 177 | 0.380 | |
| negative regulation of endopeptidase activity | GO:0010951 | 44 | 0.378 | Mouse |
| positive regulation of protein modification by small protein conjugation or removal | GO:1903322 | 30 | 0.377 | Human Fly |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 62 | 0.374 | Mouse |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 65 | 0.366 | Mouse |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.364 | Mouse |
| detection of stimulus | GO:0051606 | 84 | 0.361 | Mouse |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 47 | 0.360 | Human Mouse |
| macromolecule catabolic process | GO:0009057 | 281 | 0.355 | Human |
| regulation of inflammatory response | GO:0050727 | 147 | 0.349 | Fly |
| cellular response to carbohydrate stimulus | GO:0071322 | 50 | 0.345 | Mouse |
| regulation of actin filament polymerization | GO:0030833 | 38 | 0.343 | |
| negative regulation of nf kappab transcription factor activity | GO:0032088 | 15 | 0.341 | Human |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.339 | Human |
| regulation of homeostatic process | GO:0032844 | 182 | 0.339 | Mouse |
| negative regulation of cytokine production | GO:0001818 | 84 | 0.337 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.337 | |
| protein kinase b signaling | GO:0043491 | 74 | 0.335 | |
| regulation of defense response | GO:0031347 | 233 | 0.331 | |
| innate immune response | GO:0045087 | 157 | 0.329 | Human |
| regulation of endocytosis | GO:0030100 | 69 | 0.327 | Human |
| regulation of protein processing | GO:0070613 | 96 | 0.324 | Mouse |
| regulation of innate immune response | GO:0045088 | 91 | 0.309 | |
| histone h4 acetylation | GO:0043967 | 10 | 0.308 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.306 | Fly |
| interleukin 8 production | GO:0032637 | 4 | 0.295 | |
| negative regulation of cysteine type endopeptidase activity | GO:2000117 | 22 | 0.293 | Mouse |
| cellular protein catabolic process | GO:0044257 | 155 | 0.292 | Human |
| negative regulation of interleukin 8 production | GO:0032717 | 1 | 0.285 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.282 | |
| protein maturation | GO:0051604 | 176 | 0.280 | Mouse |
| protein processing | GO:0016485 | 163 | 0.280 | Mouse |
| activation of innate immune response | GO:0002218 | 56 | 0.277 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.272 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.262 | Human Mouse |
| histone modification | GO:0016570 | 159 | 0.260 | |
| peptidyl tyrosine modification | GO:0018212 | 145 | 0.259 | Fly |
| regulation of protein binding | GO:0043393 | 60 | 0.256 | Human Zebrafish Mouse |
| regulation of chromosome organization | GO:0033044 | 83 | 0.256 | |
| regulation of insulin secretion involved in cellular response to glucose stimulus | GO:0061178 | 31 | 0.252 | Mouse |
| leukocyte proliferation | GO:0070661 | 172 | 0.240 | |
| t cell proliferation | GO:0042098 | 120 | 0.239 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.238 | Human |
| positive regulation of rho protein signal transduction | GO:0035025 | 7 | 0.236 | |
| cellular response to monosaccharide stimulus | GO:0071326 | 47 | 0.224 | Mouse |
| regulation of secretion by cell | GO:1903530 | 249 | 0.224 | Mouse |
| negative regulation of peptidase activity | GO:0010466 | 46 | 0.213 | Mouse |
| endocytosis | GO:0006897 | 168 | 0.211 | Human Mouse |
| regulation of intracellular transport | GO:0032386 | 159 | 0.206 | |
| internal peptidyl lysine acetylation | GO:0018393 | 42 | 0.205 | |
| positive regulation of hormone secretion | GO:0046887 | 38 | 0.204 | Mouse |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 40 | 0.203 | Human |
| interleukin 12 production | GO:0032615 | 32 | 0.202 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.197 | Human |
| immune response activating signal transduction | GO:0002757 | 116 | 0.195 | |
| regulation of interleukin 8 production | GO:0032677 | 3 | 0.193 | |
| tumor necrosis factor production | GO:0032640 | 50 | 0.190 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.189 | Fly |
| peptide transport | GO:0015833 | 133 | 0.183 | Mouse |
| detection of abiotic stimulus | GO:0009582 | 60 | 0.181 | Mouse |
| positive regulation of defense response | GO:0031349 | 124 | 0.178 | |
| adult behavior | GO:0030534 | 135 | 0.178 | |
| chromatin modification | GO:0016568 | 187 | 0.176 | |
| regulation of interleukin 12 production | GO:0032655 | 30 | 0.170 | |
| positive regulation of histone modification | GO:0031058 | 28 | 0.166 | |
| regulation of chromatin modification | GO:1903308 | 57 | 0.166 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.158 | Human Mouse |
| adult locomotory behavior | GO:0008344 | 91 | 0.158 | |
| negative regulation of synapse assembly | GO:0051964 | 3 | 0.157 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.156 | Fly |
| histone acetylation | GO:0016573 | 41 | 0.155 | |
| arp2 3 complex mediated actin nucleation | GO:0034314 | 3 | 0.151 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.150 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.150 | |
| actin filament polymerization | GO:0030041 | 44 | 0.147 | |
| regulation of hormone secretion | GO:0046883 | 88 | 0.146 | Mouse |
| positive regulation of secretion by cell | GO:1903532 | 114 | 0.145 | Mouse |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.145 | |
| hormone secretion | GO:0046879 | 128 | 0.143 | Mouse |
| membrane organization | GO:0061024 | 245 | 0.142 | |
| positive regulation of insulin secretion involved in cellular response to glucose stimulus | GO:0035774 | 13 | 0.142 | Mouse |
| regulation of binding | GO:0051098 | 111 | 0.140 | Human Zebrafish Mouse |
| regulation of protein kinase b signaling | GO:0051896 | 56 | 0.137 | |
| positive regulation of growth | GO:0045927 | 104 | 0.136 | Worm |
| positive regulation of binding | GO:0051099 | 49 | 0.136 | Mouse |
| actin polymerization or depolymerization | GO:0008154 | 54 | 0.135 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 57 | 0.134 | Human Fly |
| regulation of secretion | GO:0051046 | 274 | 0.134 | Mouse |
| regulation of interleukin 1 production | GO:0032652 | 26 | 0.133 | |
| leukocyte migration | GO:0050900 | 124 | 0.133 | |
| regulation of synaptic transmission dopaminergic | GO:0032225 | 8 | 0.131 | |
| regulation of peptide hormone secretion | GO:0090276 | 75 | 0.130 | Mouse |
| chromatin organization | GO:0006325 | 206 | 0.130 | |
| cellular response to glucose stimulus | GO:0071333 | 45 | 0.129 | Mouse |
| receptor internalization | GO:0031623 | 16 | 0.127 | Human |
| positive regulation of chromosome organization | GO:2001252 | 33 | 0.126 | |
| regulation of interleukin 1 beta production | GO:0032651 | 25 | 0.125 | |
| positive regulation of peptide hormone secretion | GO:0090277 | 31 | 0.125 | Mouse |
| regulation of protein ubiquitination | GO:0031396 | 52 | 0.125 | Human |
| positive regulation of peptide secretion | GO:0002793 | 33 | 0.121 | Mouse |
| negative regulation of molecular function | GO:0044092 | 258 | 0.120 | Human Mouse Fly |
| detection of external stimulus | GO:0009581 | 61 | 0.115 | Mouse |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.115 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.115 | Mouse |
| regulation of peptide transport | GO:0090087 | 91 | 0.113 | Mouse |
| receptor mediated endocytosis | GO:0006898 | 51 | 0.113 | Human |
| regulation of histone acetylation | GO:0035065 | 19 | 0.112 | |
| positive regulation of endocytosis | GO:0045807 | 42 | 0.112 | Human |
| digestive system development | GO:0055123 | 200 | 0.111 | Fly |
| axonogenesis | GO:0007409 | 274 | 0.109 | |
| regulation of cell migration | GO:0030334 | 219 | 0.106 | Zebrafish |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.106 | Human |
| regulation of t cell activation | GO:0050863 | 170 | 0.106 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.106 | |
| cellular homeostasis | GO:0019725 | 240 | 0.105 | Mouse |
| stress activated protein kinase signaling cascade | GO:0031098 | 81 | 0.105 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.105 | |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.105 | Mouse |
| neuron neuron synaptic transmission | GO:0007270 | 69 | 0.104 | |
| negative regulation of interleukin 12 production | GO:0032695 | 10 | 0.104 | |
| digestive tract development | GO:0048565 | 190 | 0.103 | Fly |
| leukocyte differentiation | GO:0002521 | 342 | 0.103 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.102 | Mouse |
| negative regulation of protein maturation | GO:1903318 | 79 | 0.102 | Mouse |
| internal protein amino acid acetylation | GO:0006475 | 42 | 0.101 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.100 | |
| tumor necrosis factor superfamily cytokine production | GO:0071706 | 51 | 0.100 | |
| negative regulation of cell activation | GO:0050866 | 111 | 0.099 | |
| negative regulation of notch signaling pathway | GO:0045746 | 14 | 0.099 | Fly |
| regulation of clathrin mediated endocytosis | GO:2000369 | 4 | 0.099 | |
| heart process | GO:0003015 | 94 | 0.099 | |
| regulation of histone modification | GO:0031056 | 56 | 0.099 | |
| post embryonic retina morphogenesis in camera type eye | GO:0060060 | 3 | 0.097 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 84 | 0.096 | |
| positive regulation of cytoskeleton organization | GO:0051495 | 49 | 0.094 | |
| intracellular protein transport | GO:0006886 | 204 | 0.092 | |
| cellular response to hexose stimulus | GO:0071331 | 47 | 0.091 | Mouse |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.091 | Fly |
| regulation of cell projection organization | GO:0031344 | 206 | 0.091 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.090 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.090 | Mouse |
| immune effector process | GO:0002252 | 321 | 0.090 | Human |
| stress activated mapk cascade | GO:0051403 | 80 | 0.090 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.089 | Human Mouse Fly |
| heart contraction | GO:0060047 | 93 | 0.088 | |
| positive regulation of protein acetylation | GO:1901985 | 9 | 0.088 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.086 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.085 | |
| regulation of t cell proliferation | GO:0042129 | 92 | 0.083 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.082 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.082 | |
| regionalization | GO:0003002 | 337 | 0.081 | |
| cell chemotaxis | GO:0060326 | 81 | 0.081 | Human Zebrafish |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.079 | |
| regulation of tumor necrosis factor production | GO:0032680 | 49 | 0.079 | |
| vesicle fusion | GO:0006906 | 16 | 0.079 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.079 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.079 | |
| notch signaling pathway | GO:0007219 | 71 | 0.078 | Fly |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.078 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.078 | |
| establishment or maintenance of cell polarity | GO:0007163 | 86 | 0.077 | |
| peptidyl threonine phosphorylation | GO:0018107 | 31 | 0.075 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.074 | Mouse |
| b cell activation | GO:0042113 | 161 | 0.074 | |
| regulation of chromatin organization | GO:1902275 | 57 | 0.074 | |
| regulation of rho gtpase activity | GO:0032319 | 58 | 0.074 | |
| regulation of actin nucleation | GO:0051125 | 4 | 0.073 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.073 | |
| microtubule based process | GO:0007017 | 236 | 0.073 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.072 | |
| response to oxidative stress | GO:0006979 | 123 | 0.071 | |
| positive regulation of actin filament polymerization | GO:0030838 | 26 | 0.071 | |
| regulation of ral protein signal transduction | GO:0032485 | 4 | 0.071 | |
| protein acylation | GO:0043543 | 64 | 0.070 | |
| cell adhesion | GO:0007155 | 329 | 0.069 | |
| regulation of heart contraction | GO:0008016 | 77 | 0.069 | |
| regulation of blood circulation | GO:1903522 | 93 | 0.067 | |
| response to peptide | GO:1901652 | 136 | 0.067 | |
| t cell activation | GO:0042110 | 289 | 0.066 | |
| regulation of cell motility | GO:2000145 | 236 | 0.066 | Zebrafish |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.066 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.065 | |
| skin development | GO:0043588 | 220 | 0.065 | |
| transmembrane transport | GO:0055085 | 412 | 0.064 | |
| cytokine biosynthetic process | GO:0042089 | 68 | 0.063 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.063 | |
| cellular response to peptide | GO:1901653 | 92 | 0.063 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.062 | |
| positive regulation of chromatin modification | GO:1903310 | 28 | 0.062 | |
| adaptive immune response | GO:0002250 | 155 | 0.062 | |
| regulation of peptidyl lysine acetylation | GO:2000756 | 22 | 0.062 | |
| circulatory system process | GO:0003013 | 197 | 0.062 | |
| dna metabolic process | GO:0006259 | 303 | 0.061 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.061 | |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.060 | |
| negative regulation of mapk cascade | GO:0043409 | 65 | 0.060 | |
| positive regulation of receptor mediated endocytosis | GO:0048260 | 9 | 0.060 | Human |
| vesicle organization | GO:0016050 | 60 | 0.059 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.058 | |
| blood circulation | GO:0008015 | 195 | 0.058 | |
| amide transport | GO:0042886 | 138 | 0.058 | Mouse |
| regulation of receptor mediated endocytosis | GO:0048259 | 16 | 0.058 | Human |
| calcium ion transport into cytosol | GO:0060402 | 48 | 0.058 | |
| peptidyl lysine acetylation | GO:0018394 | 45 | 0.057 | |
| regulation of leukocyte mediated immunity | GO:0002703 | 104 | 0.057 | Human |
| regulation of response to wounding | GO:1903034 | 189 | 0.056 | Fly |
| regulation of tumor necrosis factor superfamily cytokine production | GO:1903555 | 50 | 0.056 | |
| regulation of t cell differentiation | GO:0045580 | 83 | 0.056 | |
| negative regulation of protein modification by small protein conjugation or removal | GO:1903321 | 20 | 0.055 | Human |
| t cell differentiation | GO:0030217 | 174 | 0.055 | |
| sequestering of metal ion | GO:0051238 | 19 | 0.055 | |
| regulation of lymphocyte mediated immunity | GO:0002706 | 84 | 0.055 | Human |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.055 | |
| locomotory exploration behavior | GO:0035641 | 10 | 0.055 | Fly |
| protein catabolic process | GO:0030163 | 221 | 0.054 | Human |
| negative regulation of tumor necrosis factor superfamily cytokine production | GO:1903556 | 17 | 0.053 | |
| response to peptide hormone | GO:0043434 | 127 | 0.053 | |
| protein localization to organelle | GO:0033365 | 185 | 0.053 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.052 | |
| positive regulation of protein binding | GO:0032092 | 29 | 0.052 | Mouse |
| immune response regulating signaling pathway | GO:0002764 | 125 | 0.052 | |
| negative regulation of nervous system development | GO:0051961 | 156 | 0.051 | |
| positive regulation of ras protein signal transduction | GO:0046579 | 13 | 0.050 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.050 | |
| negative regulation of lymphocyte activation | GO:0051250 | 91 | 0.049 | |
| regulation of metal ion transport | GO:0010959 | 106 | 0.049 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.048 | |
| gland development | GO:0048732 | 330 | 0.048 | Fly |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.048 | |
| positive regulation of cell motility | GO:2000147 | 116 | 0.047 | |
| response to light stimulus | GO:0009416 | 135 | 0.047 | Mouse |
| response to organonitrogen compound | GO:0010243 | 246 | 0.047 | |
| regulation of protein acetylation | GO:1901983 | 22 | 0.047 | |
| hexose metabolic process | GO:0019318 | 98 | 0.047 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 145 | 0.047 | |
| cilium morphogenesis | GO:0060271 | 102 | 0.047 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.046 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.046 | |
| regulation of cell activation | GO:0050865 | 289 | 0.046 | |
| regulation of myeloid cell differentiation | GO:0045637 | 96 | 0.046 | |
| calcium ion transport | GO:0006816 | 159 | 0.046 | |
| regulation of actin filament based process | GO:0032970 | 99 | 0.046 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.045 | |
| protein localization to membrane | GO:0072657 | 108 | 0.045 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.045 | |
| negative regulation of cytoskeleton organization | GO:0051494 | 36 | 0.045 | |
| negative regulation of protein ubiquitination | GO:0031397 | 19 | 0.044 | Human |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.044 | |
| epidermis development | GO:0008544 | 187 | 0.044 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.043 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.043 | Human |
| negative regulation of nik nf kappab signaling | GO:1901223 | 2 | 0.043 | |
| photoreceptor cell morphogenesis | GO:0008594 | 3 | 0.042 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.042 | |
| epidermal growth factor receptor signaling pathway via i kappab kinase nf kappab cascade | GO:0038168 | 1 | 0.042 | |
| positive regulation of peptidyl lysine acetylation | GO:2000758 | 9 | 0.042 | |
| neural tube development | GO:0021915 | 160 | 0.041 | |
| inflammatory response | GO:0006954 | 244 | 0.041 | Fly |
| establishment or maintenance of apical basal cell polarity | GO:0035088 | 21 | 0.041 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.041 | |
| regulation of actin polymerization or depolymerization | GO:0008064 | 45 | 0.041 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.040 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.040 | |
| nuclear transport | GO:0051169 | 139 | 0.040 | |
| retina development in camera type eye | GO:0060041 | 119 | 0.040 | |
| leukocyte activation involved in immune response | GO:0002366 | 126 | 0.040 | |
| cytokine metabolic process | GO:0042107 | 71 | 0.039 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.039 | |
| response to growth factor | GO:0070848 | 198 | 0.039 | Human |
| protein polymerization | GO:0051258 | 57 | 0.039 | |
| regulation of protein localization | GO:0032880 | 231 | 0.039 | |
| sensory perception | GO:0007600 | 245 | 0.039 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.039 | |
| camera type eye development | GO:0043010 | 266 | 0.039 | |
| protein ubiquitination | GO:0016567 | 171 | 0.039 | Human |
| dendrite development | GO:0016358 | 115 | 0.039 | |
| asymmetric neuroblast division | GO:0055059 | 1 | 0.038 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.038 | |
| nuclear division | GO:0000280 | 158 | 0.038 | |
| actin filament depolymerization | GO:0030042 | 15 | 0.037 | |
| male gamete generation | GO:0048232 | 285 | 0.037 | |
| primary neural tube formation | GO:0014020 | 95 | 0.037 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.037 | |
| negative regulation of t cell activation | GO:0050868 | 65 | 0.037 | |
| positive regulation of cell migration | GO:0030335 | 109 | 0.037 | |
| regulation of arp2 3 complex mediated actin nucleation | GO:0034315 | 1 | 0.036 | |
| regulation of cell size | GO:0008361 | 72 | 0.036 | |
| regulation of cytokine biosynthetic process | GO:0042035 | 59 | 0.035 | |
| regulation of ion transport | GO:0043269 | 215 | 0.035 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.035 | |
| protein targeting | GO:0006605 | 143 | 0.034 | |
| synapse organization | GO:0050808 | 125 | 0.034 | |
| genetic imprinting | GO:0071514 | 27 | 0.034 | |
| regulation of receptor internalization | GO:0002090 | 7 | 0.034 | Human |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.034 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.034 | |
| cell fate commitment | GO:0045165 | 210 | 0.034 | |
| response to reactive oxygen species | GO:0000302 | 56 | 0.034 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.034 | |
| cellular calcium ion homeostasis | GO:0006874 | 119 | 0.033 | |
| action potential | GO:0001508 | 78 | 0.033 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.033 | |
| cation homeostasis | GO:0055080 | 212 | 0.033 | |
| negative regulation of homeostatic process | GO:0032845 | 71 | 0.033 | |
| regulation of histone h4 acetylation | GO:0090239 | 3 | 0.033 | |
| regulation of lymphocyte proliferation | GO:0050670 | 117 | 0.033 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.033 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.032 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 127 | 0.032 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.032 | |
| mitochondrion organization | GO:0007005 | 134 | 0.032 | |
| positive regulation of protein complex assembly | GO:0031334 | 45 | 0.032 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.032 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.032 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.032 | |
| regulation of protein transport | GO:0051223 | 163 | 0.032 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.031 | Human |
| dna repair | GO:0006281 | 107 | 0.031 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.031 | |
| synapse assembly | GO:0007416 | 56 | 0.030 | |
| regulation of system process | GO:0044057 | 200 | 0.030 | |
| germinal center formation | GO:0002467 | 16 | 0.030 | |
| synaptic transmission | GO:0007268 | 329 | 0.030 | |
| establishment or maintenance of bipolar cell polarity | GO:0061245 | 21 | 0.029 | |
| negative regulation of actin filament polymerization | GO:0030837 | 11 | 0.029 | |
| epithelial tube formation | GO:0072175 | 130 | 0.029 | |
| positive regulation of t cell activation | GO:0050870 | 101 | 0.029 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.029 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.028 | Human |
| phagocytosis | GO:0006909 | 66 | 0.028 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.028 | |
| oxidation reduction process | GO:0055114 | 342 | 0.028 | |
| regulation of adrenergic receptor signaling pathway | GO:0071877 | 4 | 0.028 | |
| protein complex disassembly | GO:0043241 | 40 | 0.028 | |
| negative regulation of t cell differentiation | GO:0045581 | 23 | 0.028 | |
| organelle localization | GO:0051640 | 179 | 0.028 | |
| plasma membrane organization | GO:0007009 | 90 | 0.028 | |
| response to insulin | GO:0032868 | 100 | 0.028 | |
| response to oxygen levels | GO:0070482 | 62 | 0.028 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.028 | |
| tissue migration | GO:0090130 | 68 | 0.027 | |
| protein localization to plasma membrane | GO:0072659 | 57 | 0.027 | |
| nuclear import | GO:0051170 | 95 | 0.027 | |
| cilium assembly | GO:0042384 | 81 | 0.027 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.027 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.027 | Mouse |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.027 | |
| positive regulation of cell projection organization | GO:0031346 | 95 | 0.027 | |
| establishment of monopolar cell polarity | GO:0061162 | 8 | 0.027 | |
| second messenger mediated signaling | GO:0019932 | 73 | 0.027 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.027 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.027 | |
| response to nerve growth factor | GO:1990089 | 3 | 0.026 | |
