Mus musculus

0 known processes

Pnp2

purine-nucleoside phosphorylase 2

Pnp2 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nicotinamide nucleotide biosynthetic processGO:001935941.000
pyridine containing compound catabolic processGO:007252641.000
pyridine nucleotide biosynthetic processGO:001936341.000
positive regulation of t cell mediated cytotoxicityGO:0001916150.999
interleukin 2 secretionGO:007097070.998
purine deoxyribonucleoside triphosphate metabolic processGO:000921570.972
deoxyribose phosphate metabolic processGO:001969290.970
coenzyme biosynthetic processGO:0009108230.955
deoxyribonucleoside triphosphate metabolic processGO:000920090.925
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.904
regulation of t cell mediated cytotoxicityGO:0001914180.902
nad metabolic processGO:001967470.894
cofactor biosynthetic processGO:0051188410.856
coenzyme metabolic processGO:0006732520.837
purine nucleotide biosynthetic processGO:0006164650.826
leukocyte mediated cytotoxicityGO:0001909620.814
deoxyribonucleotide metabolic processGO:0009262140.805
apoptotic mitochondrial changesGO:0008637480.798
cell killingGO:0001906670.796
t cell mediated immunityGO:0002456500.787
regulation of leukocyte mediated cytotoxicityGO:0001910380.726
intrinsic apoptotic signaling pathwayGO:00971931320.720
regulation of b cell differentiationGO:0045577230.706
ribonucleotide biosynthetic processGO:0009260590.665
t cell mediated cytotoxicityGO:0001913260.649
purine nucleoside metabolic processGO:00422782410.638
regulation of lymphocyte apoptotic processGO:0070228410.624
purine ribonucleotide metabolic processGO:00091502900.598
ribonucleoside metabolic processGO:00091192450.591
ribose phosphate biosynthetic processGO:0046390590.582
regulation of t cell mediated immunityGO:0002709340.576
positive regulation of alpha beta t cell differentiationGO:0046638280.572
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.568
regulation of alpha beta t cell differentiationGO:0046637350.564
mitochondrion organizationGO:00070051340.563
ribonucleoside biosynthetic processGO:0042455210.552
dna repairGO:00062811070.552
positive regulation of lymphocyte differentiationGO:0045621610.550
pyridine nucleotide metabolic processGO:0019362120.549
negative regulation of t cell apoptotic processGO:0070233180.547
regulation of cell killingGO:0031341400.542
positive regulation of leukocyte mediated immunityGO:0002705700.536
nucleoside phosphate biosynthetic processGO:1901293790.529
positive regulation of cell killingGO:0031343330.526
nucleoside phosphate metabolic processGO:00067533380.526
cofactor metabolic processGO:0051186800.523
regulation of lymphocyte mediated immunityGO:0002706840.522
regulation of b cell activationGO:0050864810.508
carbohydrate derivative biosynthetic processGO:19011371830.508
nicotinamide nucleotide metabolic processGO:0046496120.500
nucleotide biosynthetic processGO:0009165780.499
cytokine productionGO:00018163190.495
purine nucleoside biosynthetic processGO:0042451190.490
pyridine containing compound metabolic processGO:0072524140.486
purine containing compound biosynthetic processGO:0072522700.484
regulation of lymphocyte proliferationGO:00506701170.482
lymphocyte mediated immunityGO:00024491390.479
response to ionizing radiationGO:0010212420.473
nucleobase containing small molecule metabolic processGO:00550863520.473
organonitrogen compound biosynthetic processGO:19015661920.473
urate metabolic processGO:004641520.460
glycosyl compound catabolic processGO:19016582060.458
purine ribonucleoside biosynthetic processGO:0046129190.457
adaptive immune responseGO:00022501550.454
apoptotic signaling pathwayGO:00971903060.447
regulation of t cell differentiationGO:0045580830.445
guanosine containing compound metabolic processGO:19010681440.443
response to gamma radiationGO:0010332220.435
t cell apoptotic processGO:0070231390.430
leukocyte mediated immunityGO:00024431740.428
ribonucleotide metabolic processGO:00092592910.426
glycosyl compound biosynthetic processGO:1901659210.426
purine ribonucleotide biosynthetic processGO:0009152590.426
t cell proliferationGO:00420981200.423
gtp metabolic processGO:00460391440.418
small molecule biosynthetic processGO:00442831320.417
nucleoside metabolic processGO:00091162460.411
positive regulation of alpha beta t cell activationGO:0046635390.410
cellular response to dna damage stimulusGO:00069742070.409
b cell differentiationGO:0030183780.407
alpha beta t cell differentiationGO:0046632690.406
guanosine containing compound catabolic processGO:19010691440.402
ribonucleoside triphosphate metabolic processGO:00091992200.398
positive regulation of t cell differentiationGO:0045582520.390
oxidoreduction coenzyme metabolic processGO:0006733160.389
nucleoside biosynthetic processGO:0009163210.389
lymphocyte differentiationGO:00300982420.386
ribonucleoside catabolic processGO:00424542060.386
negative regulation of lymphocyte apoptotic processGO:0070229240.379
positive regulation of cell activationGO:00508671580.379
positive regulation of lymphocyte activationGO:00512511400.376
organophosphate biosynthetic processGO:00904071220.370
heterocycle catabolic processGO:00467002800.370
ribose phosphate metabolic processGO:00196932910.365
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.364
glycosyl compound metabolic processGO:19016572460.359
regulation of t cell activationGO:00508631700.358
cellular nitrogen compound catabolic processGO:00442702800.358
interleukin 2 productionGO:0032623330.357
organonitrogen compound catabolic processGO:19015652640.355
positive regulation of b cell activationGO:0050871490.354
regulation of leukocyte apoptotic processGO:2000106560.352
regulation of cell activationGO:00508652890.351
positive regulation of dna repairGO:004573930.350
positive regulation of lymphocyte proliferationGO:0050671700.348
nucleotide metabolic processGO:00091173320.345
dna metabolic processGO:00062593030.339
leukocyte apoptotic processGO:0071887710.338
positive regulation of response to dna damage stimulusGO:2001022140.334
immune effector processGO:00022523210.333
purine nucleoside catabolic processGO:00061522050.332
t cell differentiationGO:00302171740.331
nucleoside catabolic processGO:00091642060.328
nucleoside triphosphate metabolic processGO:00091412300.328
b cell activationGO:00421131610.326
leukocyte differentiationGO:00025213420.324
regulation of leukocyte mediated immunityGO:00027031040.324
regulation of cellular response to stressGO:00801351590.323
purine deoxyribonucleotide metabolic processGO:000915160.322
purine ribonucleoside metabolic processGO:00461282410.320
regulation of response to dna damage stimulusGO:2001020340.318
purine ribonucleoside catabolic processGO:00461302050.318
positive regulation of t cell activationGO:00508701010.316
carbohydrate derivative catabolic processGO:19011362310.315
positive regulation of leukocyte differentiationGO:1902107860.315
purine ribonucleoside triphosphate metabolic processGO:00092052200.314
purine nucleoside triphosphate metabolic processGO:00091442260.312
regulation of alpha beta t cell activationGO:0046634530.308
positive regulation of leukocyte proliferationGO:0070665730.307
purine containing compound catabolic processGO:00725232130.304
regulation of t cell proliferationGO:0042129920.303
lymphocyte proliferationGO:00466511640.300
organic cyclic compound catabolic processGO:19013612950.298
purine containing compound metabolic processGO:00725213110.296
purine nucleotide metabolic processGO:00061633020.296
lymphocyte apoptotic processGO:0070227540.295
positive regulation of lymphocyte mediated immunityGO:0002708620.295
regulation of lymphocyte activationGO:00512492400.290
leukocyte proliferationGO:00706611720.283
regulation of t cell apoptotic processGO:0070232280.274
aromatic compound catabolic processGO:00194392860.268
t cell activationGO:00421102890.263
positive regulation of t cell proliferationGO:0042102520.263
regulation of lymphocyte differentiationGO:00456191070.255
positive regulation of t cell mediated immunityGO:0002711240.244
alpha beta t cell activationGO:0046631910.244
regulation of leukocyte differentiationGO:19021051590.243
cell type specific apoptotic processGO:00972852680.242
positive regulation of adaptive immune responseGO:0002821610.238
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.234
positive regulation of b cell differentiationGO:0045579130.229
innate immune responseGO:00450871570.219
cytokine secretionGO:0050663720.211
positive regulation of immune effector processGO:00026991070.209
regulation of leukocyte proliferationGO:00706631210.186
cellular amino acid metabolic processGO:00065201030.180
protein secretionGO:00093061110.174
nad biosynthetic processGO:000943530.152
cellular ketone metabolic processGO:0042180840.105
pyridine containing compound biosynthetic processGO:007252550.095
ribonucleoside triphosphate biosynthetic processGO:000920160.092
response to drugGO:0042493750.086
cellular lipid metabolic processGO:00442553230.084
negative regulation of leukocyte apoptotic processGO:2000107310.084
amine metabolic processGO:0009308450.081
transmembrane transportGO:00550854120.073
regulation of cellular amino acid metabolic processGO:000652150.071
nitrogen compound transportGO:00717052710.070
regulation of hydrolase activityGO:00513362460.069
oxidation reduction processGO:00551143420.067
cation transportGO:00068123990.067
regulation of cellular catabolic processGO:00313292420.058
positive regulation of hydrolase activityGO:00513451480.054
circulatory system processGO:00030131970.052
lipid biosynthetic processGO:00086101790.052
cellular macromolecule catabolic processGO:00442652060.050
regulation of cellular ketone metabolic processGO:0010565660.048
positive regulation of cellular amine metabolic processGO:003324050.048
nucleotide catabolic processGO:00091662170.046
cation homeostasisGO:00550802120.046
positive regulation of cellular catabolic processGO:00313311480.045
purine nucleoside triphosphate biosynthetic processGO:000914570.044
regulation of cellular amine metabolic processGO:0033238200.044
monocarboxylic acid metabolic processGO:00327871910.044
ras protein signal transductionGO:0007265770.042
ion transmembrane transportGO:00342203610.042
cellular ion homeostasisGO:00068731650.040
cellular modified amino acid metabolic processGO:0006575630.039
macromolecule catabolic processGO:00090572810.039
cellular homeostasisGO:00197252400.039
protein catabolic processGO:00301632210.038
cellular protein catabolic processGO:00442571550.038
cellular amine metabolic processGO:0044106440.037
cellular response to molecule of bacterial originGO:0071219830.034
peptidyl amino acid modificationGO:00181933360.034
regulation of neuron apoptotic processGO:00435231220.032
organic hydroxy compound metabolic processGO:19016152030.032
regulation of response to woundingGO:19030341890.032
carbohydrate metabolic processGO:00059752300.031
cellular response to lipidGO:00713961450.031
negative regulation of molecular functionGO:00440922580.030
protein import into nucleusGO:0006606950.029
negative regulation of apoptotic signaling pathwayGO:20012341040.029
response to organic cyclic compoundGO:00140701980.029
regulation of organelle organizationGO:00330432890.029
membrane organizationGO:00610242450.029
neuron deathGO:00709971540.028
nucleoside phosphate catabolic processGO:19012922220.028
positive regulation of protein modification processGO:00314012990.028
blood circulationGO:00080151950.028
skin developmentGO:00435882200.027
regulation of purine nucleotide metabolic processGO:19005421690.027
positive regulation of apoptotic signaling pathwayGO:2001235950.027
purine nucleotide catabolic processGO:00061952110.027
positive regulation of cell deathGO:00109422240.027
purine ribonucleotide catabolic processGO:00091542080.027
regulation of kinase activityGO:00435492490.026
regulation of neuron deathGO:19012141340.026
extracellular structure organizationGO:00430621480.026
positive regulation of programmed cell deathGO:00430682180.025
regulation of peptidase activityGO:0052547960.025
protein localization to organelleGO:00333651850.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
response to lipopolysaccharideGO:00324961280.025
nucleoside triphosphate catabolic processGO:00091432050.024
response to molecule of bacterial originGO:00022371430.024
sequestering of metal ionGO:0051238190.024
response to organonitrogen compoundGO:00102432460.024
regulation of cytokine productionGO:00018172660.023
regulation of transferase activityGO:00513382630.023
gland developmentGO:00487323300.023
respiratory tube developmentGO:00303231670.023
positive regulation of mapk cascadeGO:00434101700.022
regulation of defense responseGO:00313472330.022
nucleocytoplasmic transportGO:00069131390.022
ribonucleotide catabolic processGO:00092612080.021
glycerolipid metabolic processGO:00464861220.021
cellular metal ion homeostasisGO:00068751510.021
regulation of mapk cascadeGO:00434082480.021
regulation of apoptotic signaling pathwayGO:20012331970.021
regulation of transmembrane transportGO:00347621280.021
inorganic cation transmembrane transportGO:00986622070.020
protein localization to nucleusGO:00345041210.020
negative regulation of immune system processGO:00026832090.020
multicellular organism growthGO:00352641610.020
purine ribonucleoside triphosphate biosynthetic processGO:000920660.020
inorganic ion transmembrane transportGO:00986602340.020
carboxylic acid biosynthetic processGO:0046394860.020
cation transmembrane transportGO:00986552660.019
regulation of purine nucleotide catabolic processGO:00331211220.019
ribonucleoside triphosphate catabolic processGO:00092031990.019
amide transportGO:00428861380.019
reactive oxygen species metabolic processGO:0072593840.019
regulation of nucleotide metabolic processGO:00061401690.019
regulation of tube sizeGO:0035150570.019
striated muscle tissue developmentGO:00147062930.019
nuclear transportGO:00511691390.019
regulation of intracellular transportGO:00323861590.018
negative regulation of intracellular signal transductionGO:19025321670.018
positive regulation of purine nucleotide metabolic processGO:19005441140.018
regulation of secretion by cellGO:19035302490.018
maintenance of locationGO:0051235890.018
fatty acid metabolic processGO:00066311210.018
spermatogenesisGO:00072832840.018
regulation of homeostatic processGO:00328441820.018
positive regulation of peptidase activityGO:0010952490.018
regulation of cell motilityGO:20001452360.018
myeloid leukocyte differentiationGO:00025731190.018
regulation of anatomical structure sizeGO:00900661780.018
cytoplasmic transportGO:00164822340.018
small gtpase mediated signal transductionGO:0007264970.017
epithelial cell developmentGO:00020641590.017
regulation of protein localizationGO:00328802310.017
positive regulation of nucleoside metabolic processGO:0045979910.017
endocytosisGO:00068971680.017
regulation of reactive oxygen species metabolic processGO:2000377400.017
protein maturationGO:00516041760.017
vascular process in circulatory systemGO:0003018620.017
placenta developmentGO:00018901400.017
nadph regenerationGO:000674020.017
extrinsic apoptotic signaling pathwayGO:00971911260.016
extracellular matrix organizationGO:00301981470.016
regulation of cell projection organizationGO:00313442060.016
rho protein signal transductionGO:0007266320.016
muscle cell differentiationGO:00426922610.016
regulation of protein transportGO:00512231630.016
signal transduction in absence of ligandGO:0038034550.016
blood vessel morphogenesisGO:00485142850.016
hexose catabolic processGO:001932030.016
cellular protein complex assemblyGO:00436231160.016
multicellular organismal signalingGO:0035637910.016
angiogenesisGO:00015252010.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.016
regulation of ion transportGO:00432692150.016
negative regulation of cellular amine metabolic processGO:003323910.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
sensory organ morphogenesisGO:00905962420.015
positive regulation of apoptotic processGO:00430652170.015
negative regulation of phosphorus metabolic processGO:00105631840.015
sensory perceptionGO:00076002450.015
g protein coupled receptor signaling pathwayGO:00071862430.015
divalent metal ion transportGO:00708381720.015
glucose metabolic processGO:0006006920.015
cellular response to cytokine stimulusGO:00713451890.015
positive regulation of secretion by cellGO:19035321140.015
regulation of membrane potentialGO:00423911920.015
cellular response to hormone stimulusGO:00328701500.015
organic acid biosynthetic processGO:0016053860.015
regulation of blood vessel sizeGO:0050880560.015
negative regulation of cellular component organizationGO:00511291940.015
organic hydroxy compound biosynthetic processGO:1901617770.015
organic anion transportGO:00157111370.015
cellular divalent inorganic cation homeostasisGO:00725031270.015
positive regulation of transferase activityGO:00513471670.014
homeostasis of number of cellsGO:00488722100.014
male gamete generationGO:00482322850.014
positive regulation of nucleotide metabolic processGO:00459811140.014
regulation of protein kinase activityGO:00458592320.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.014
regulation of ossificationGO:00302781120.014
negative regulation of protein modification processGO:00314001630.014
anion transportGO:00068201770.014
epithelial tube morphogenesisGO:00605623030.014
regulation of blood pressureGO:0008217930.014
response to growth factorGO:00708481980.014
divalent inorganic cation transportGO:00725111780.014
microtubule based processGO:00070172360.014
carbohydrate homeostasisGO:00335001280.014
positive regulation of nucleotide catabolic processGO:0030813880.014
establishment of protein localization to organelleGO:00725941180.014
peptide transportGO:00158331330.014
protein polymerizationGO:0051258570.014
regulation of neuron differentiationGO:00456642810.014
negative regulation of cell proliferationGO:00082852960.013
cell activation involved in immune responseGO:00022631260.013
divalent inorganic cation homeostasisGO:00725071380.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
regulation of secretionGO:00510462740.013
skeletal system developmentGO:00015013560.013
purine ribonucleoside monophosphate metabolic processGO:0009167800.013
carboxylic acid catabolic processGO:0046395510.013
regulation of nucleotide catabolic processGO:00308111220.013
response to radiationGO:00093141650.013
cellular response to biotic stimulusGO:0071216920.013
positive regulation of growthGO:00459271040.013
muscle tissue developmentGO:00605373080.013
positive regulation of secretionGO:00510471300.013
nuclear importGO:0051170950.013
steroid metabolic processGO:00082021190.013
regulation of interleukin 8 productionGO:003267730.013
response to inorganic substanceGO:0010035960.013
anatomical structure homeostasisGO:00602491450.013
vesicle organizationGO:0016050600.013
blastocyst developmentGO:0001824800.013
positive regulation of purine nucleotide catabolic processGO:0033123880.013
lung developmentGO:00303241640.013
transmission of nerve impulseGO:0019226760.012
substantia nigra developmentGO:002176220.012
regulation of nucleoside metabolic processGO:00091181300.012
regulation of cell migrationGO:00303342190.012
erythrocyte differentiationGO:0030218880.012
multi multicellular organism processGO:00447061090.012
intracellular protein transportGO:00068862040.012
cellular chemical homeostasisGO:00550822150.012
metal ion homeostasisGO:00550651890.012
protein localization to membraneGO:00726571080.012
cell adhesionGO:00071553290.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
interleukin 8 productionGO:003263740.012
regulation of interleukin 1 alpha productionGO:003265040.012
action potentialGO:0001508780.012
synaptic transmissionGO:00072683290.012
retina development in camera type eyeGO:00600411190.012
regulation of multi organism processGO:00439001110.012
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.012
lymphocyte activation involved in immune responseGO:0002285930.012
neuron apoptotic processGO:00514021420.012
calcium ion homeostasisGO:00550741270.012
lipid localizationGO:00108761260.012
positive regulation of protein kinase activityGO:00458601440.011
protein oligomerizationGO:0051259670.011
wnt signaling pathwayGO:00160551880.011
stem cell differentiationGO:00488632680.011
regulation of establishment of protein localizationGO:00702011810.011
negative regulation of lymphocyte activationGO:0051250910.011
glycoprotein metabolic processGO:00091001160.011
single organism cell adhesionGO:00986021560.011
cellular response to lipopolysaccharideGO:0071222770.011
meiotic cell cycleGO:00513211220.011
stress activated mapk cascadeGO:0051403800.011
myeloid cell differentiationGO:00300992330.011
regulation of system processGO:00440572000.011
regulation of cytoplasmic transportGO:19036491120.011
mapk cascadeGO:00001652810.011
anion transmembrane transportGO:0098656710.011
triglyceride metabolic processGO:0006641510.011
positive regulation of protein phosphorylationGO:00019342420.011
regulation of proteolysisGO:00301621640.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
cellular calcium ion homeostasisGO:00068741190.011
multicellular organismal homeostasisGO:00488711640.011
negative regulation of protein metabolic processGO:00512482820.011
response to extracellular stimulusGO:00099911270.011
modification dependent protein catabolic processGO:00199411330.011
regulation of inflammatory responseGO:00507271470.011
negative regulation of protein phosphorylationGO:00019331260.011
cellular response to growth factor stimulusGO:00713631970.011
engulfment of apoptotic cellGO:004365230.011
striated muscle cell developmentGO:00550021250.011
regulation of protein targetingGO:1903533610.011
hexose metabolic processGO:0019318980.011
branching morphogenesis of an epithelial tubeGO:00487541590.011
tissue homeostasisGO:00018941150.011
modification dependent macromolecule catabolic processGO:00436321330.011
regulation of ras protein signal transductionGO:00465781140.011
gonad developmentGO:00084061410.011
defense response to other organismGO:00985421970.011
transcription factor import into nucleusGO:0042991260.011
sensory perception of mechanical stimulusGO:00509541070.010
response to acid chemicalGO:00011011110.010
positive regulation of protein catabolic processGO:0045732600.010
pharynx developmentGO:006046510.010
regulation of endopeptidase activityGO:0052548890.010
respiratory system developmentGO:00605411900.010
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.010
positive regulation of organelle organizationGO:00106381280.010
erk1 and erk2 cascadeGO:0070371770.010
positive regulation of t helper 1 cell differentiationGO:004562740.010
t cell receptor signaling pathwayGO:0050852460.010
glucose catabolic processGO:000600730.010
calcium ion transportGO:00068161590.010
dephosphorylationGO:00163111290.010
regulation of actin filament based processGO:0032970990.010
organelle fissionGO:00482851700.010

Pnp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.833
immune system diseaseDOID:291400.833
primary immunodeficiency diseaseDOID:61200.677
combined t cell and b cell immunodeficiencyDOID:62800.388
disease of cellular proliferationDOID:1456600.022
musculoskeletal system diseaseDOID:1700.020
connective tissue diseaseDOID:6500.020
nervous system diseaseDOID:86300.018
organ system cancerDOID:005068600.016
cancerDOID:16200.016
inherited metabolic disorderDOID:65500.010
disease of metabolismDOID:001466700.010