Mus musculus

40 known processes

Pdia3

protein disulfide isomerase associated 3

(Aliases: Plca,PDI-Q2,Erp,PLC[a],ERp57,Grp58,PDI,PI-PLC,ERp60,ERp61,58kDa)

Pdia3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to topologically incorrect proteinGO:0035966250.917
er nucleus signaling pathwayGO:0006984270.872
cellular response to topologically incorrect proteinGO:0035967250.792
response to unfolded proteinGO:0006986210.770
endoplasmic reticulum unfolded protein responseGO:0030968190.714
response to endoplasmic reticulum stressGO:0034976530.574
glycoprotein biosynthetic processGO:0009101890.393
macromolecule glycosylationGO:0043413550.383
protein n linked glycosylationGO:0006487120.195
glycoprotein metabolic processGO:00091001160.193
cellular protein catabolic processGO:00442571550.155
posttranslational protein targeting to membraneGO:000662020.150
cotranslational protein targeting to membraneGO:000661320.132
carbohydrate derivative biosynthetic processGO:19011371830.125
carbohydrate metabolic processGO:00059752300.125
transmembrane transportGO:00550854120.115
protein glycosylationGO:0006486550.112
protein catabolic processGO:00301632210.106
response to atpGO:003319880.097
protein targeting to erGO:004504720.095
lipid localizationGO:00108761260.095
mrna metabolic processGO:0016071840.093
cellular macromolecule catabolic processGO:00442652060.089
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.087
positive regulation of cell motilityGO:20001471160.083
maintenance of locationGO:0051235890.082
response to organonitrogen compoundGO:00102432460.078
midgut developmentGO:000749440.076
muscle cell differentiationGO:00426922610.075
macromolecule catabolic processGO:00090572810.074
glycosylationGO:0070085620.070
cellular response to external stimulusGO:0071496880.067
response to starvationGO:0042594650.067
regulation of tube sizeGO:0035150570.063
membrane lipid biosynthetic processGO:0046467320.063
cellular response to extracellular stimulusGO:0031668810.062
positive regulation of growth hormone secretionGO:006012430.062
protein transmembrane transportGO:007180680.062
amine metabolic processGO:0009308450.061
cellular response to starvationGO:0009267570.059
lipid storageGO:0019915360.058
inorganic ion transmembrane transportGO:00986602340.054
cellular response to antibioticGO:007123640.053
fertilizationGO:00095661270.053
cellular response to nutrient levelsGO:0031669640.053
positive regulation of endocytosisGO:0045807420.053
substantia nigra developmentGO:002176220.052
protein localization to organelleGO:00333651850.051
response to organic cyclic compoundGO:00140701980.051
cellular lipid metabolic processGO:00442553230.049
ion transmembrane transportGO:00342203610.048
cellular component assembly involved in morphogenesisGO:00109271390.047
positive regulation of hydrolase activityGO:00513451480.046
er associated ubiquitin dependent protein catabolic processGO:0030433100.045
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.044
regulation of secretionGO:00510462740.044
fatty acid metabolic processGO:00066311210.044
endodermal digestive tract morphogenesisGO:006103140.043
germ cell developmentGO:00072811850.042
cellular response to interleukin 4GO:0071353210.042
response to nutrient levelsGO:00316671090.041
nitrogen compound transportGO:00717052710.041
monocarboxylic acid metabolic processGO:00327871910.041
response to extracellular stimulusGO:00099911270.041
regulation of apoptotic signaling pathwayGO:20012331970.041
regulation of hydrolase activityGO:00513362460.038
cellular protein complex assemblyGO:00436231160.037
positive regulation of growthGO:00459271040.037
Worm
cellular nitrogen compound catabolic processGO:00442702800.037
positive regulation of cell substrate adhesionGO:0010811470.037
cerebellum developmentGO:0021549770.036
ear developmentGO:00435832000.036
cellular amino acid metabolic processGO:00065201030.036
cilium assemblyGO:0042384810.035
extracellular matrix organizationGO:00301981470.035
cation transmembrane transportGO:00986552660.035
protein targeting to membraneGO:0006612200.035
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.034
response to growth factorGO:00708481980.034
peptidyl asparagine modificationGO:001819610.034
regulation of organelle organizationGO:00330432890.033
spermatid developmentGO:00072861080.033
regulation of phosphoprotein phosphatase activityGO:004366630.033
positive regulation of cell migrationGO:00303351090.033
positive regulation of cell deathGO:00109422240.033
aromatic compound catabolic processGO:00194392860.033
chemotaxisGO:00069352470.032
digestive tract morphogenesisGO:00485461470.031
positive regulation of protein secretionGO:0050714520.031
positive regulation of programmed cell deathGO:00430682180.031
protein n linked glycosylation via asparagineGO:001827910.031
regulation of cell motilityGO:20001452360.031
spermatogenesisGO:00072832840.031
cell adhesionGO:00071553290.030
endocytosisGO:00068971680.030
compound eye developmentGO:004874910.029
regulation of cellular ketone metabolic processGO:0010565660.029
organic acid transportGO:00158491010.029
cerebellar cortex developmentGO:0021695480.029
cellular response to organic cyclic compoundGO:0071407870.028
mrna processingGO:0006397630.028
protein foldingGO:0006457280.028
Yeast Worm
apoptotic signaling pathwayGO:00971903060.027
positive regulation of secretion by cellGO:19035321140.027
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.027
positive regulation of dendritic cell chemotaxisGO:200051010.027
establishment of synaptic vesicle localizationGO:0097480570.027
digestive system developmentGO:00551232000.027
regulation of cell migrationGO:00303342190.026
striated muscle myosin thick filament assemblyGO:007168810.026
cell chemotaxisGO:0060326810.026
cellular amine metabolic processGO:0044106440.026
carboxylic acid transportGO:00469421000.026
response to oxygen levelsGO:0070482620.026
vascular process in circulatory systemGO:0003018620.025
lipid biosynthetic processGO:00086101790.025
engulfment of apoptotic cellGO:004365230.025
positive regulation of apoptotic signaling pathwayGO:2001235950.025
anion transportGO:00068201770.025
actin filament polymerizationGO:0030041440.025
positive regulation of protein modification processGO:00314012990.024
response to antibioticGO:0046677110.024
embryonic epithelial tube formationGO:00018381300.024
response to organophosphorusGO:0046683220.024
regulation of lymphocyte activationGO:00512492400.024
positive regulation of transferase activityGO:00513471670.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.023
translationGO:0006412930.023
intracellular protein transportGO:00068862040.023
maintenance of protein localization in organelleGO:007259520.023
microtubule cytoskeleton organizationGO:00002261570.023
cellular response to biotic stimulusGO:0071216920.022
regulation of endocytosisGO:0030100690.022
neural tube developmentGO:00219151600.022
negative regulation of cellular protein metabolic processGO:00322692470.022
meiotic cell cycleGO:00513211220.022
ribonucleoside metabolic processGO:00091192450.022
divalent inorganic cation transportGO:00725111780.022
regulation of cellular catabolic processGO:00313292420.022
male gamete generationGO:00482322850.022
actin filament organizationGO:00070151130.021
pigmentationGO:0043473710.021
cation transportGO:00068123990.020
regulation of cellular response to stressGO:00801351590.020
phagocytosisGO:0006909660.020
posttranscriptional regulation of gene expressionGO:00106081550.020
muscle tissue developmentGO:00605373080.020
hindbrain morphogenesisGO:0021575460.020
sphingolipid biosynthetic processGO:0030148260.020
meiotic nuclear divisionGO:00071261150.019
digestive tract developmentGO:00485651900.019
muscle system processGO:00030121410.019
modification dependent macromolecule catabolic processGO:00436321330.019
calcium ion transportGO:00068161590.019
peptidyl amino acid modificationGO:00181933360.019
barbed end actin filament cappingGO:005101660.019
oxidation reduction processGO:00551143420.019
Yeast
regulation of neuron differentiationGO:00456642810.019
actin polymerization or depolymerizationGO:0008154540.019
chaperone mediated protein foldingGO:0061077100.019
establishment or maintenance of apical basal cell polarityGO:0035088210.018
extracellular structure organizationGO:00430621480.018
transmission of nerve impulseGO:0019226760.018
t cell activationGO:00421102890.018
ubiquitin dependent protein catabolic processGO:00065111290.018
catecholamine metabolic processGO:0006584300.018
positive regulation of cell developmentGO:00107202370.018
cellular divalent inorganic cation homeostasisGO:00725031270.018
circulatory system processGO:00030131970.018
cellular response to transforming growth factor beta stimulusGO:0071560880.018
negative regulation of cellular response to growth factor stimulusGO:0090288460.018
regulation of cell adhesionGO:00301551540.017
gtp metabolic processGO:00460391440.017
renal system developmentGO:00720012250.017
negative regulation of cell developmentGO:00107211690.017
modification dependent protein catabolic processGO:00199411330.017
cytoplasmic transportGO:00164822340.017
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.017
regulation of transferase activityGO:00513382630.017
multi multicellular organism processGO:00447061090.017
Worm
hepaticobiliary system developmentGO:0061008670.016
cellular homeostasisGO:00197252400.016
anatomical structure arrangementGO:0048532200.016
spermatid differentiationGO:00485151150.016
skeletal system developmentGO:00015013560.016
rna splicing via transesterification reactionsGO:0000375430.016
substrate adhesion dependent cell spreadingGO:0034446300.016
negative regulation of protein depolymerizationGO:1901880210.016
protein targetingGO:00066051430.016
cellular ketone metabolic processGO:0042180840.016
clathrin mediated endocytosisGO:007258370.016
cellular response to cytokine stimulusGO:00713451890.016
hindbrain developmentGO:00309021280.015
organic cyclic compound catabolic processGO:19013612950.015
ribonucleotide metabolic processGO:00092592910.015
cellular response to lipidGO:00713961450.015
protein secretionGO:00093061110.015
divalent inorganic cation homeostasisGO:00725071380.015
cation homeostasisGO:00550802120.015
response to hypoxiaGO:0001666580.015
negative regulation of actin filament depolymerizationGO:003083590.015
lymphocyte differentiationGO:00300982420.015
developmental maturationGO:00217001930.015
interleukin 8 secretionGO:007260630.015
gland developmentGO:00487323300.015
leukocyte chemotaxisGO:0030595690.015
response to purine containing compoundGO:0014074280.015
cellular response to toxic substanceGO:009723770.015
lipid transportGO:0006869980.015
negative regulation of nervous system developmentGO:00519611560.015
positive regulation of cellular amino acid metabolic processGO:004576430.014
positive regulation of cell activationGO:00508671580.014
regulation of actin filament based processGO:0032970990.014
regulation of cell morphogenesis involved in differentiationGO:00107691510.014
action potentialGO:0001508780.014
protein refoldingGO:004202610.014
l amino acid transportGO:0015807320.014
multicellular organismal agingGO:0010259240.014
establishment of protein localization to membraneGO:0090150540.014
inorganic cation transmembrane transportGO:00986622070.014
regulation of membrane potentialGO:00423911920.014
immunoglobulin productionGO:0002377730.014
receptor mediated endocytosisGO:0006898510.014
regulation of cell projection organizationGO:00313442060.014
regulation of secretion by cellGO:19035302490.014
urogenital system developmentGO:00016552610.014
membrane organizationGO:00610242450.014
ribonucleoside triphosphate catabolic processGO:00092031990.014
lateral inhibitionGO:004633110.014
mrna splicing via spliceosomeGO:0000398430.014
positive regulation of nervous system developmentGO:00519622210.014
interleukin 8 productionGO:003263740.014
positive regulation of protein transportGO:0051222930.014
placenta developmentGO:00018901400.014
phenol containing compound metabolic processGO:0018958600.014
homeostasis of number of cellsGO:00488722100.014
nuclear divisionGO:00002801580.013
regulation of hormone levelsGO:00108172110.013
positive regulation of protein phosphorylationGO:00019342420.013
positive regulation of cellular amine metabolic processGO:003324050.013
regulation of multi organism processGO:00439001110.013
monocarboxylic acid biosynthetic processGO:0072330610.013
leukocyte differentiationGO:00025213420.013
glycoprotein catabolic processGO:000651650.013
regulation of vesicle mediated transportGO:00606271390.013
positive regulation of cardiac muscle contractionGO:006045220.013
midbrain developmentGO:0030901350.013
regulation of phagocytosisGO:0050764330.013
oocyte constructionGO:000730820.013
regulation of cellular amine metabolic processGO:0033238200.013
regulation of cell substrate adhesionGO:0010810730.013
cellular response to organonitrogen compoundGO:00714171450.013
regulation of actin cytoskeleton organizationGO:0032956840.013
establishment of protein localization to endoplasmic reticulumGO:007259920.013
macroautophagyGO:0016236210.013
cerebellum morphogenesisGO:0021587420.013
cellular response to growth factor stimulusGO:00713631970.013
regulation of homeostatic processGO:00328441820.013
regulation of translationGO:0006417710.013
amide transportGO:00428861380.013
positive regulation of protein serine threonine kinase activityGO:00719021060.013
neural nucleus developmentGO:0048857220.013
positive regulation of fatty acid oxidationGO:004632140.013
regulation of actin polymerization or depolymerizationGO:0008064450.013
toxin transportGO:1901998380.013
regulation of chemotaxisGO:0050920530.012
insulin secretionGO:0030073890.012
fat cell differentiationGO:00454441600.012
regulation of cellular amino acid metabolic processGO:000652150.012
regulation of cellular component biogenesisGO:00440871810.012
purine nucleoside triphosphate catabolic processGO:00091462030.012
organelle disassemblyGO:190300820.012
positive regulation of protein kinase activityGO:00458601440.012
regulation of cellular response to growth factor stimulusGO:0090287820.012
molting cycleGO:0042303900.012
positive regulation of cell adhesionGO:0045785800.012
nucleobase containing small molecule metabolic processGO:00550863520.012
cell recognitionGO:0008037830.012
positive regulation of cell growthGO:0030307330.012
regulation of anatomical structure sizeGO:00900661780.012
purine nucleoside metabolic processGO:00422782410.012
single fertilizationGO:0007338820.012
response to heatGO:0009408270.012
blood circulationGO:00080151950.012
multicellular organism growthGO:00352641610.012
Worm
negative regulation of cellular component organizationGO:00511291940.012
actin cytoskeleton organizationGO:00300362200.012
regulation of protein depolymerizationGO:1901879260.012
muscle contractionGO:00069361010.012
steroid metabolic processGO:00082021190.012
microtubule based processGO:00070172360.012
negative regulation of molecular functionGO:00440922580.012
neural tube formationGO:00018411080.012
regulation of cell cycleGO:00517262810.012
ribonucleoside triphosphate metabolic processGO:00091992200.012
organophosphate catabolic processGO:00464342320.012
intra golgi vesicle mediated transportGO:000689110.012
blood vessel morphogenesisGO:00485142850.012
regulation of mrna processingGO:0050684410.011
retina homeostasisGO:0001895230.011
very long chain fatty acid biosynthetic processGO:004276120.011
heterocycle catabolic processGO:00467002800.011
regulation of actin filament lengthGO:0030832450.011
regulation of mapk cascadeGO:00434082480.011
calcium ion homeostasisGO:00550741270.011
sequestering of metal ionGO:0051238190.011
embryonic placenta developmentGO:0001892980.011
regulation of actin filament depolymerizationGO:0030834130.011
establishment of organelle localizationGO:00516561220.011
cellular response to lipopolysaccharideGO:0071222770.011
amino acid transportGO:0006865610.011
cellular ion homeostasisGO:00068731650.011
anatomical structure maturationGO:0071695490.011
autophagyGO:0006914450.011
dopaminergic neuron differentiationGO:0071542140.011
response to transforming growth factor betaGO:0071559880.011
notch signaling pathwayGO:0007219710.011
carboxylic acid biosynthetic processGO:0046394860.011
rna splicingGO:0008380540.011
response to estrogenGO:0043627240.011
cilium morphogenesisGO:00602711020.011
t cell differentiationGO:00302171740.011
transforming growth factor beta receptor signaling pathwayGO:0007179710.011
nucleoside phosphate catabolic processGO:19012922220.011
organic anion transportGO:00157111370.011
regulation of ion transportGO:00432692150.011
rna processingGO:00063961050.011
er overload responseGO:000698360.011
metencephalon developmentGO:0022037890.010
regulation of interleukin 8 productionGO:003267730.010
response to inorganic substanceGO:0010035960.010
regulation of cell growthGO:0001558910.010
hexose metabolic processGO:0019318980.010
kidney developmentGO:00018222130.010
dephosphorylationGO:00163111290.010
cellularizationGO:000734910.010
negative regulation of protein complex disassemblyGO:0043242220.010
neural precursor cell proliferationGO:00613511210.010
myosin filament organizationGO:003103330.010
cytokine productionGO:00018163190.010
single organism cell adhesionGO:00986021560.010
b cell differentiationGO:0030183780.010

Pdia3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.045
disease of metabolismDOID:001466700.045
central nervous system diseaseDOID:33100.039
disease of anatomical entityDOID:700.039
nervous system diseaseDOID:86300.039
carbohydrate metabolic disorderDOID:297800.016
disease of cellular proliferationDOID:1456600.014
connective tissue diseaseDOID:6500.013
bone diseaseDOID:008000100.013
bone development diseaseDOID:008000600.013
musculoskeletal system diseaseDOID:1700.013
disease of mental healthDOID:15000.011
cancerDOID:16200.011
neurodegenerative diseaseDOID:128900.011
organ system cancerDOID:005068600.010