Mus musculus

33 known processes

Dpyd

dihydropyrimidine dehydrogenase

(Aliases: DPD,E330028L06Rik,MGC37940,AI315208)

Dpyd biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143420.368
cellular lipid metabolic processGO:00442553230.261
steroid metabolic processGO:00082021190.220
fatty acid metabolic processGO:00066311210.196
monocarboxylic acid metabolic processGO:00327871910.183
small molecule catabolic processGO:0044282710.183
organic hydroxy compound metabolic processGO:19016152030.178
cellular amino acid metabolic processGO:00065201030.167
vitamin d3 metabolic processGO:007064030.131
calcitriol biosynthetic process from calciolGO:003637830.131
vitamin d biosynthetic processGO:004236830.124
cellular alcohol biosynthetic processGO:004410830.122
xenobiotic catabolic processGO:004217810.121
lipid biosynthetic processGO:00086101790.121
cellular ketone metabolic processGO:0042180840.116
fat soluble vitamin biosynthetic processGO:004236240.115
amine metabolic processGO:0009308450.115
alcohol metabolic processGO:00060661160.113
cofactor metabolic processGO:0051186800.108
small molecule biosynthetic processGO:00442831320.104
naphthalene metabolic processGO:001893110.095
organic acid catabolic processGO:0016054510.092
secondary alcohol metabolic processGO:190265230.089
cellular lipid catabolic processGO:0044242520.087
regulation of cellular ketone metabolic processGO:0010565660.087
cellular alcohol metabolic processGO:004410730.086
cellular amine metabolic processGO:0044106440.084
carboxylic acid catabolic processGO:0046395510.075
glycerolipid metabolic processGO:00464861220.073
organic acid biosynthetic processGO:0016053860.067
response to organic cyclic compoundGO:00140701980.064
blood circulationGO:00080151950.064
carbohydrate metabolic processGO:00059752300.062
neutral lipid metabolic processGO:0006638570.054
regulation of cellular amino acid metabolic processGO:000652150.054
nucleotide metabolic processGO:00091173320.053
lipid catabolic processGO:0016042690.050
drug metabolic processGO:001714440.049
acylglycerol metabolic processGO:0006639550.049
cell adhesionGO:00071553290.048
naphthalene containing compound metabolic processGO:009042010.046
organonitrogen compound catabolic processGO:19015652640.045
alpha amino acid metabolic processGO:1901605590.044
positive regulation of cellular amino acid metabolic processGO:004576430.043
nucleobase containing small molecule metabolic processGO:00550863520.042
regulation of cellular amine metabolic processGO:0033238200.041
organic hydroxy compound biosynthetic processGO:1901617770.041
response to acid chemicalGO:00011011110.039
cellular response to lipidGO:00713961450.039
negative regulation of cellular protein metabolic processGO:00322692470.039
cellular response to cadmium ionGO:007127630.038
unsaturated fatty acid metabolic processGO:0033559310.038
fatty acid derivative metabolic processGO:1901568330.038
transmembrane transportGO:00550854120.038
nucleoside phosphate metabolic processGO:00067533380.037
vitamin metabolic processGO:0006766230.037
short chain fatty acid catabolic processGO:001962620.036
camera type eye developmentGO:00430102660.036
lipid localizationGO:00108761260.036
lipid transportGO:0006869980.036
purine ribonucleotide metabolic processGO:00091502900.035
triglyceride metabolic processGO:0006641510.035
response to organonitrogen compoundGO:00102432460.035
negative regulation of cellular amine metabolic processGO:003323910.035
maintenance of locationGO:0051235890.035
ribose phosphate metabolic processGO:00196932910.034
circulatory system processGO:00030131970.034
nitrogen compound transportGO:00717052710.034
coenzyme metabolic processGO:0006732520.034
cation homeostasisGO:00550802120.033
terpenoid metabolic processGO:0006721250.033
purine nucleotide metabolic processGO:00061633020.033
positive regulation of cellular amine metabolic processGO:003324050.033
long chain fatty acid metabolic processGO:0001676260.033
renal system developmentGO:00720012250.033
cytokine productionGO:00018163190.032
urogenital system developmentGO:00016552610.031
monosaccharide metabolic processGO:00059961060.030
organic cyclic compound catabolic processGO:19013612950.029
response to testosteroneGO:003357430.029
heterocycle catabolic processGO:00467002800.029
isoprenoid metabolic processGO:0006720290.029
peptidyl amino acid modificationGO:00181933360.028
regulation of secretion by cellGO:19035302490.028
fatty acid catabolic processGO:0009062250.028
cation transmembrane transportGO:00986552660.028
regulation of secretionGO:00510462740.028
establishment of blood nerve barrierGO:000806530.028
innate immune responseGO:00450871570.028
response to inorganic substanceGO:0010035960.028
negative regulation of protein metabolic processGO:00512482820.027
sensory perceptionGO:00076002450.027
receptor biosynthetic processGO:003280030.027
organonitrogen compound biosynthetic processGO:19015661920.026
synaptic transmissionGO:00072683290.026
negative regulation of cell proliferationGO:00082852960.026
reactive nitrogen species metabolic processGO:200105700.026
fat cell differentiationGO:00454441600.026
purine containing compound metabolic processGO:00725213110.026
toxin catabolic processGO:000940710.026
cation transportGO:00068123990.026
anion transportGO:00068201770.026
ribonucleotide metabolic processGO:00092592910.026
icosanoid metabolic processGO:0006690330.026
forebrain developmentGO:00309003020.026
cellular chemical homeostasisGO:00550822150.025
organic anion transportGO:00157111370.025
polyol metabolic processGO:0019751260.025
hexose metabolic processGO:0019318980.025
monocarboxylic acid catabolic processGO:0072329270.025
purine ribonucleoside metabolic processGO:00461282410.025
regulation of homeostatic processGO:00328441820.025
positive regulation of nervous system developmentGO:00519622210.024
response to molecule of bacterial originGO:00022371430.024
positive regulation of fatty acid oxidationGO:004632140.024
nucleoside triphosphate metabolic processGO:00091412300.024
sulfur compound metabolic processGO:00067901000.024
alcohol biosynthetic processGO:0046165430.024
nucleoside metabolic processGO:00091162460.023
muscle tissue developmentGO:00605373080.023
steroid biosynthetic processGO:0006694470.023
regulation of lipid metabolic processGO:00192161180.023
ribonucleoside metabolic processGO:00091192450.023
drug catabolic processGO:004273720.022
aromatic compound catabolic processGO:00194392860.022
negative regulation of molecular functionGO:00440922580.022
regulation of membrane potentialGO:00423911920.022
cellular response to cytokine stimulusGO:00713451890.022
carbohydrate biosynthetic processGO:0016051740.022
cellular response to organonitrogen compoundGO:00714171450.022
positive regulation of secretion by cellGO:19035321140.022
cell type specific apoptotic processGO:00972852680.022
response to lipopolysaccharideGO:00324961280.022
acetate metabolic processGO:000608310.022
cellular response to lipopolysaccharideGO:0071222770.022
cellular homeostasisGO:00197252400.022
cellular ion homeostasisGO:00068731650.021
ion transmembrane transportGO:00342203610.021
respiratory tube developmentGO:00303231670.021
organophosphate catabolic processGO:00464342320.021
retina development in camera type eyeGO:00600411190.021
vascular process in circulatory systemGO:0003018620.021
reactive oxygen species metabolic processGO:0072593840.021
cytoplasmic transportGO:00164822340.021
ribonucleoside triphosphate metabolic processGO:00091992200.021
response to extracellular stimulusGO:00099911270.021
alpha amino acid catabolic processGO:1901606180.021
rhythmic processGO:00485111740.021
digestive system developmentGO:00551232000.021
kidney developmentGO:00018222130.021
regulation of nucleotide metabolic processGO:00061401690.021
positive regulation of secretionGO:00510471300.021
rho protein signal transductionGO:0007266320.021
response to oxidative stressGO:00069791230.021
regulation of cell adhesionGO:00301551540.021
regulation of hydrolase activityGO:00513362460.021
arachidonic acid metabolic processGO:0019369140.020
cellular response to growth factor stimulusGO:00713631970.020
ras protein signal transductionGO:0007265770.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.020
cellular carbohydrate metabolic processGO:00442621190.020
response to nutrient levelsGO:00316671090.020
regulation of cellular catabolic processGO:00313292420.020
regulation of system processGO:00440572000.020
sensory organ morphogenesisGO:00905962420.020
organic hydroxy compound catabolic processGO:1901616250.020
regulation of hormone levelsGO:00108172110.020
positive regulation of cell developmentGO:00107202370.020
cellular amino acid catabolic processGO:0009063250.020
digestive tract developmentGO:00485651900.020
fatty acid oxidationGO:0019395280.019
negative regulation of cellular amino acid metabolic processGO:004576300.019
carboxylic acid biosynthetic processGO:0046394860.019
cell substrate adhesionGO:00315891300.019
regulation of chloride transportGO:200122520.019
cellular amide metabolic processGO:0043603580.019
cellular response to molecule of bacterial originGO:0071219830.019
multicellular organismal signalingGO:0035637910.019
circadian regulation of gene expressionGO:0032922480.019
defense response to other organismGO:00985421970.019
acetylcholine catabolic processGO:000658110.019
circadian rhythmGO:00076231140.019
cellular response to inorganic substanceGO:0071241370.018
negative regulation of phosphorylationGO:00423261660.018
multi multicellular organism processGO:00447061090.018
epithelial cell developmentGO:00020641590.018
regulation of hormone secretionGO:0046883880.018
dephosphorylationGO:00163111290.018
carboxylic acid transportGO:00469421000.018
purine nucleoside metabolic processGO:00422782410.018
cellular response to biotic stimulusGO:0071216920.018
glycosyl compound metabolic processGO:19016572460.018
striated muscle tissue developmentGO:00147062930.018
regulation of reactive oxygen species metabolic processGO:2000377400.018
positive regulation of programmed cell deathGO:00430682180.018
regulation of neuron differentiationGO:00456642810.018
carbohydrate derivative biosynthetic processGO:19011371830.018
monocarboxylic acid biosynthetic processGO:0072330610.018
skin developmentGO:00435882200.018
regulation of cytokine productionGO:00018172660.018
cellular biogenic amine metabolic processGO:0006576280.018
stem cell differentiationGO:00488632680.018
muscle cell differentiationGO:00426922610.017
thermosensory behaviorGO:004004010.017
cellular response to acid chemicalGO:0071229680.017
retinoid metabolic processGO:0001523240.017
myeloid cell differentiationGO:00300992330.017
short chain fatty acid metabolic processGO:004645960.017
generation of precursor metabolites and energyGO:00060911030.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
positive regulation of apoptotic processGO:00430652170.017
regulation of anatomical structure sizeGO:00900661780.017
regulation of epithelial cell proliferationGO:00506781410.017
endocytosisGO:00068971680.017
endocrine processGO:0050886390.017
response to growth factorGO:00708481980.017
positive regulation of hydrolase activityGO:00513451480.017
nucleoside phosphate catabolic processGO:19012922220.017
hematopoietic progenitor cell differentiationGO:00022441430.017
skeletal system developmentGO:00015013560.017
lipid oxidationGO:0034440290.017
dna metabolic processGO:00062593030.017
immune effector processGO:00022523210.017
cellular nitrogen compound catabolic processGO:00442702800.017
macromolecule catabolic processGO:00090572810.017
regulation of fatty acid metabolic processGO:0019217280.017
organophosphate biosynthetic processGO:00904071220.017
glial cell differentiationGO:00100011310.016
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressureGO:000199830.016
protein oligomerizationGO:0051259670.016
lipid modificationGO:0030258650.016
cholesterol metabolic processGO:0008203560.016
gland developmentGO:00487323300.016
regulation of tube sizeGO:0035150570.016
purine ribonucleotide catabolic processGO:00091542080.016
amide transportGO:00428861380.016
monosaccharide biosynthetic processGO:0046364440.016
reactive oxygen species biosynthetic processGO:190340980.016
medium chain fatty acid metabolic processGO:005179110.016
connective tissue developmentGO:00614481790.016
hormone secretionGO:00468791280.016
hindbrain developmentGO:00309021280.016
regulation of reactive oxygen species biosynthetic processGO:190342620.016
ribonucleotide catabolic processGO:00092612080.015
regulation of vesicle mediated transportGO:00606271390.015
regulation of cell motilityGO:20001452360.015
response to radiationGO:00093141650.015
hormone metabolic processGO:0042445860.015
locomotory behaviorGO:00076261950.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
neuron deathGO:00709971540.015
triglyceride biosynthetic processGO:0019432170.015
protein catabolic processGO:00301632210.015
heme metabolic processGO:0042168160.015
glucose metabolic processGO:0006006920.015
oxidative demethylationGO:007098910.015
negative regulation of protein modification processGO:00314001630.015
positive regulation of protein modification processGO:00314012990.015
response to drugGO:0042493750.015
respiratory system developmentGO:00605411900.015
purine nucleotide catabolic processGO:00061952110.015
cell activation involved in immune responseGO:00022631260.015
g protein coupled receptor signaling pathwayGO:00071862430.015
purine nucleoside triphosphate metabolic processGO:00091442260.015
purine ribonucleoside catabolic processGO:00461302050.015
regulation of blood pressureGO:0008217930.014
energy derivation by oxidation of organic compoundsGO:0015980770.014
posttranscriptional regulation of gene expressionGO:00106081550.014
regulation of proteolysisGO:00301621640.014
glucose homeostasisGO:00425931280.014
membrane organizationGO:00610242450.014
regulation of angiogenesisGO:0045765810.014
regulation of systemic arterial blood pressureGO:0003073610.014
regulation of cell projection organizationGO:00313442060.014
regulation of ion transportGO:00432692150.014
nucleotide catabolic processGO:00091662170.014
negative regulation of phosphate metabolic processGO:00459361840.014
muscle system processGO:00030121410.014
axonogenesisGO:00074092740.014
regulation of kinase activityGO:00435492490.014
limb developmentGO:00601731660.014
blood vessel morphogenesisGO:00485142850.014
response to light stimulusGO:00094161350.014
cellular metal ion homeostasisGO:00068751510.014
purine nucleoside catabolic processGO:00061522050.014
skeletal system morphogenesisGO:00487052030.014
cellular response to hormone stimulusGO:00328701500.014
developmental growth involved in morphogenesisGO:00605601380.014
purine containing compound catabolic processGO:00725232130.014
regulation of blood vessel sizeGO:0050880560.014
activation of immune responseGO:00022531380.014
nucleoside bisphosphate metabolic processGO:003386590.014
mesonephric tubule developmentGO:0072164940.014
multicellular organism growthGO:00352641610.014
epithelial cell proliferationGO:00506731740.014
peptide secretionGO:00027901140.014
asymmetric neuroblast divisionGO:005505910.014
substantia nigra developmentGO:002176220.014
positive regulation of reactive oxygen species metabolic processGO:2000379110.014
mapk cascadeGO:00001652810.014
regulation of cell migrationGO:00303342190.014
response to peptideGO:19016521360.014
chemotaxisGO:00069352470.014
lipid homeostasisGO:0055088630.013
regulation of peptide transportGO:0090087910.013
midgut developmentGO:000749440.013
protein modification by small protein conjugationGO:00324461870.013
angiogenesisGO:00015252010.013
regulation of lipid transportGO:0032368360.013
regulation of protein maturationGO:1903317960.013
cellular response to organic cyclic compoundGO:0071407870.013
positive regulation of homeostatic processGO:0032846640.013
regulation of fatty acid oxidationGO:0046320100.013
lung developmentGO:00303241640.013
organelle localizationGO:00516401790.013
developmental maturationGO:00217001930.013
organelle fissionGO:00482851700.013
regulation of purine nucleotide metabolic processGO:19005421690.013
asymmetric stem cell divisionGO:009872230.013
glycerolipid catabolic processGO:0046503160.013
peptide hormone secretionGO:00300721090.013
regulation of carbohydrate metabolic processGO:0006109750.013
divalent inorganic cation homeostasisGO:00725071380.013
positive regulation of cell deathGO:00109422240.013
ossificationGO:00015032160.013
protein maturationGO:00516041760.013
sterol metabolic processGO:0016125580.013
linoleic acid metabolic processGO:004365160.013
cellular response to external stimulusGO:0071496880.013
positive regulation of neuron differentiationGO:00456661410.013
nucleoside catabolic processGO:00091642060.013
ribonucleoside bisphosphate metabolic processGO:003387590.013
cellular response to extracellular stimulusGO:0031668810.013
regulation of cellular carbohydrate metabolic processGO:0010675750.013
sequestering of metal ionGO:0051238190.013
regulation of feeding behaviorGO:006025930.013
carbohydrate derivative catabolic processGO:19011362310.013
regulation of mapk cascadeGO:00434082480.012
porphyrin containing compound metabolic processGO:0006778220.012
fatty acid biosynthetic processGO:0006633410.012
peptide metabolic processGO:0006518460.012
male gamete generationGO:00482322850.012
cartilage developmentGO:00512161400.012
response to nitrosative stressGO:005140910.012
glycerolipid biosynthetic processGO:0045017500.012
negative regulation of protein phosphorylationGO:00019331260.012
acylglycerol catabolic processGO:0046464110.012
positive regulation of cellular catabolic processGO:00313311480.012
regulation of vasculature developmentGO:1901342880.012
kidney epithelium developmentGO:00720731210.012
neuronal action potentialGO:0019228540.012
cholesterol homeostasisGO:0042632440.012
regulation of organelle organizationGO:00330432890.012
acyl coa metabolic processGO:0006637190.012
organic hydroxy compound transportGO:0015850930.012
bone developmentGO:00603481200.012
nucleoside phosphate biosynthetic processGO:1901293790.012
regulation of lipid biosynthetic processGO:0046890540.012
regulation of cell morphogenesis involved in differentiationGO:00107691510.012
purine nucleoside monophosphate metabolic processGO:0009126810.012
cholesterol storageGO:001087840.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
protein processingGO:00164851630.012
skeletal muscle organ developmentGO:00605381630.012
regulation of intracellular transportGO:00323861590.012
cellular response to nutrient levelsGO:0031669640.012
sequestering of calcium ionGO:0051208180.012
positive regulation of lipid metabolic processGO:0045834400.012
very low density lipoprotein particle assemblyGO:003437920.012
regulation of cell cycleGO:00517262810.012
neuron projection guidanceGO:00974851410.012
t cell activationGO:00421102890.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
negative regulation of cellular component organizationGO:00511291940.011
toxin metabolic processGO:000940450.011
multicellular organismal homeostasisGO:00488711640.011
cell fate commitmentGO:00451652100.011
cell growthGO:00160491300.011
metencephalon developmentGO:0022037890.011
transmission of nerve impulseGO:0019226760.011
regulation of protein localizationGO:00328802310.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
interleukin 8 productionGO:003263740.011
sterol homeostasisGO:0055092450.011
liver developmentGO:0001889660.011
carbohydrate homeostasisGO:00335001280.011
sulfate assimilationGO:000010330.011
tissue homeostasisGO:00018941150.011
wnt signaling pathwayGO:00160551880.011
nucleoside triphosphate catabolic processGO:00091432050.011
gonad developmentGO:00084061410.011
response to peptide hormoneGO:00434341270.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
glycoprotein metabolic processGO:00091001160.011
negative regulation of phosphorus metabolic processGO:00105631840.011
regulation of blood circulationGO:1903522930.011
regulation of wnt signaling pathwayGO:00301111230.011
protein localization to organelleGO:00333651850.011
hexose biosynthetic processGO:0019319390.011
nucleoside monophosphate metabolic processGO:0009123850.011
gliogenesisGO:00420631410.011
central nervous system neuron differentiationGO:00219531620.011
regulation of establishment of protein localizationGO:00702011810.011
embryonic organ morphogenesisGO:00485622760.011
response to reactive oxygen speciesGO:0000302560.011
organic acid transportGO:00158491010.011
metal ion homeostasisGO:00550651890.011
leukocyte mediated immunityGO:00024431740.011
regulation of apoptotic signaling pathwayGO:20012331970.011
regulation of protein transportGO:00512231630.011
regulation of cellular response to growth factor stimulusGO:0090287820.011
peptidyl tyrosine modificationGO:00182121450.011
spermatid differentiationGO:00485151150.011
cerebellum developmentGO:0021549770.011
stem cell proliferationGO:00720891170.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
oligopeptide transmembrane transportGO:003567240.011
regulation of protein kinase activityGO:00458592320.011
amino acid transmembrane transportGO:0003333370.011
ethanol metabolic processGO:000606730.011
nucleocytoplasmic transportGO:00069131390.011
positive regulation of protein kinase activityGO:00458601440.011
pyruvate metabolic processGO:0006090280.011
appendage developmentGO:00487361660.011
organ growthGO:00352651170.011
negative regulation of immune system processGO:00026832090.011
nuclear transportGO:00511691390.011
intracellular protein transportGO:00068862040.011
negative regulation of cell migrationGO:0030336590.011
lipid storageGO:0019915360.010
positive regulation of nucleoside metabolic processGO:0045979910.010
negative regulation of lipid metabolic processGO:0045833300.010
thioester metabolic processGO:0035383190.010
regionalizationGO:00030023370.010
protein modification by small protein conjugation or removalGO:00706472070.010
lymphocyte differentiationGO:00300982420.010
transition metal ion homeostasisGO:0055076540.010
photoreceptor cell morphogenesisGO:000859430.010
regulation of nucleoside metabolic processGO:00091181300.010
regulation of cellular response to stressGO:00801351590.010
regulation of cell activationGO:00508652890.010
cardiocyte differentiationGO:0035051870.010
response to insulinGO:00328681000.010
epidermis developmentGO:00085441870.010
heart morphogenesisGO:00030071780.010
anion transmembrane transportGO:0098656710.010
cellular response to starvationGO:0009267570.010
gluconeogenesisGO:0006094390.010
regulation of estrogen secretionGO:200086110.010
defense response to bacteriumGO:00427421190.010
response to starvationGO:0042594650.010
homeostasis of number of cellsGO:00488722100.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.010
regulation of fat cell differentiationGO:0045598810.010
regulation of glucose metabolic processGO:0010906600.010
diterpenoid metabolic processGO:0016101240.010
aspartate family amino acid metabolic processGO:0009066100.010
acylglycerol biosynthetic processGO:0046463180.010
regulation of organ morphogenesisGO:20000271440.010
morphogenesis of a branching structureGO:00017632030.010
rna processingGO:00063961050.010
small gtpase mediated signal transductionGO:0007264970.010
telencephalon developmentGO:00215371860.010
regulation of ossificationGO:00302781120.010
uronic acid metabolic processGO:000606320.010
cellular response to transforming growth factor beta stimulusGO:0071560880.010

Dpyd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.041
disease of anatomical entityDOID:700.022
cardiovascular system diseaseDOID:128700.022
inherited metabolic disorderDOID:65500.020
nervous system diseaseDOID:86300.019
hypertensionDOID:1076300.014
essential hypertensionDOID:1082500.014
vascular diseaseDOID:17800.014
artery diseaseDOID:005082800.014
immune system diseaseDOID:291400.014
musculoskeletal system diseaseDOID:1700.014
hematopoietic system diseaseDOID:7400.011
sensory system diseaseDOID:005015500.011