Mus musculus

26 known processes

Fndc5

fibronectin type III domain containing 5

(Aliases: Pxp,1500001L03Rik,AI836596,PeP,MGC129464,MGC129465,C87088)

Fndc5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation transmembrane transportGO:00986552660.211
ion transmembrane transportGO:00342203610.192
inorganic ion transmembrane transportGO:00986602340.190
inorganic cation transmembrane transportGO:00986622070.106
regulation of membrane potentialGO:00423911920.082
transmembrane transportGO:00550854120.081
cellular amino acid metabolic processGO:00065201030.081
cation transportGO:00068123990.080
actin cytoskeleton organizationGO:00300362200.063
potassium ion transportGO:0006813520.059
regulation of system processGO:00440572000.059
cellular potassium ion transportGO:0071804430.058
muscle tissue developmentGO:00605373080.055
amine metabolic processGO:0009308450.054
cellular amine metabolic processGO:0044106440.052
regulation of cellular amine metabolic processGO:0033238200.048
regulation of transmembrane transportGO:00347621280.047
cardiac muscle cell contractionGO:008600370.046
regulation of cellular component biogenesisGO:00440871810.045
myosin filament assemblyGO:003103420.045
cell adhesionGO:00071553290.043
sodium ion transmembrane transportGO:0035725490.043
regulation of ion transmembrane transporter activityGO:0032412540.042
cellular ketone metabolic processGO:0042180840.042
cation homeostasisGO:00550802120.040
ventricular cardiac muscle cell action potentialGO:008600540.040
regulation of cellular ketone metabolic processGO:0010565660.039
membrane organizationGO:00610242450.039
purine nucleoside triphosphate metabolic processGO:00091442260.039
striated muscle tissue developmentGO:00147062930.038
synaptic transmissionGO:00072683290.035
cofactor metabolic processGO:0051186800.035
ribonucleotide metabolic processGO:00092592910.035
positive regulation of cellular amine metabolic processGO:003324050.034
regulation of ion transportGO:00432692150.034
skeletal muscle organ developmentGO:00605381630.033
regulation of cellular amino acid metabolic processGO:000652150.033
muscle cell differentiationGO:00426922610.032
epithelial tube morphogenesisGO:00605623030.032
coenzyme metabolic processGO:0006732520.032
nucleobase containing small molecule metabolic processGO:00550863520.031
organic anion transportGO:00157111370.031
cellular homeostasisGO:00197252400.031
potassium ion transmembrane transportGO:0071805430.031
lipid biosynthetic processGO:00086101790.031
macromolecule catabolic processGO:00090572810.031
posttranscriptional regulation of gene expressionGO:00106081550.031
anion transportGO:00068201770.031
protein catabolic processGO:00301632210.030
neurotransmitter transportGO:0006836760.030
carboxylic acid transportGO:00469421000.030
cellular lipid metabolic processGO:00442553230.030
cellular chemical homeostasisGO:00550822150.029
plasma membrane organizationGO:0007009900.029
nucleotide metabolic processGO:00091173320.029
divalent metal ion transportGO:00708381720.029
organonitrogen compound biosynthetic processGO:19015661920.029
positive regulation of protein phosphorylationGO:00019342420.029
action potentialGO:0001508780.028
endomembrane system organizationGO:00102561470.028
purine ribonucleoside metabolic processGO:00461282410.028
multicellular organismal signalingGO:0035637910.028
aromatic compound catabolic processGO:00194392860.028
ribonucleoside metabolic processGO:00091192450.028
purine containing compound metabolic processGO:00725213110.028
skeletal system developmentGO:00015013560.028
nitrogen compound transportGO:00717052710.027
nucleoside phosphate catabolic processGO:19012922220.027
organophosphate catabolic processGO:00464342320.027
cellular response to lipidGO:00713961450.027
regulation of apoptotic signaling pathwayGO:20012331970.027
developmental maturationGO:00217001930.027
nucleoside phosphate metabolic processGO:00067533380.026
striated muscle myosin thick filament assemblyGO:007168810.026
cardiac muscle contractionGO:0060048320.026
potassium ion homeostasisGO:005507540.026
regulation of neurotransmitter levelsGO:0001505870.026
protein localization to membraneGO:00726571080.026
sensory organ morphogenesisGO:00905962420.026
extracellular matrix organizationGO:00301981470.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
striated muscle cell developmentGO:00550021250.025
regulation of actin filament based processGO:0032970990.025
sequestering of calcium ionGO:0051208180.025
actin filament based movementGO:0030048230.025
cellular protein complex assemblyGO:00436231160.025
muscle cell developmentGO:00550011330.025
regulation of metal ion transportGO:00109591060.025
positive regulation of protein modification processGO:00314012990.025
metal ion homeostasisGO:00550651890.025
muscle contractionGO:00069361010.024
single organismal cell cell adhesionGO:00163371310.024
cellular nitrogen compound catabolic processGO:00442702800.024
leukocyte differentiationGO:00025213420.024
nucleoside metabolic processGO:00091162460.024
spermatogenesisGO:00072832840.024
organic hydroxy compound metabolic processGO:19016152030.024
apoptotic signaling pathwayGO:00971903060.023
regulation of organelle organizationGO:00330432890.023
regulation of purine nucleotide metabolic processGO:19005421690.023
striated muscle contractionGO:0006941450.023
purine ribonucleoside triphosphate metabolic processGO:00092052200.023
fertilizationGO:00095661270.023
regulation of secretion by cellGO:19035302490.023
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.023
mapk cascadeGO:00001652810.022
cellular protein catabolic processGO:00442571550.022
cell type specific apoptotic processGO:00972852680.022
fat cell differentiationGO:00454441600.022
regulation of cell adhesionGO:00301551540.022
actin mediated cell contractionGO:0070252150.022
heart processGO:0003015940.022
organelle assemblyGO:00709251770.022
positive regulation of nervous system developmentGO:00519622210.022
divalent inorganic cation transportGO:00725111780.022
embryonic organ morphogenesisGO:00485622760.022
extracellular structure organizationGO:00430621480.021
rho protein signal transductionGO:0007266320.021
purine nucleoside triphosphate catabolic processGO:00091462030.021
renal sodium ion transportGO:000309620.021
carbohydrate derivative catabolic processGO:19011362310.021
purine nucleotide metabolic processGO:00061633020.021
regulation of sodium ion transmembrane transporter activityGO:200064990.021
actin filament polymerizationGO:0030041440.020
organic cyclic compound catabolic processGO:19013612950.020
peptidyl amino acid modificationGO:00181933360.020
coenzyme biosynthetic processGO:0009108230.020
regulation of cytoskeleton organizationGO:00514931220.020
regulation of myotube differentiationGO:0010830620.020
single organism cell adhesionGO:00986021560.020
male gamete generationGO:00482322850.020
neuron neuron synaptic transmissionGO:0007270690.020
positive regulation of ion transportGO:0043270650.020
neuronal action potentialGO:0019228540.020
ribonucleotide catabolic processGO:00092612080.019
oxidation reduction processGO:00551143420.019
positive regulation of apoptotic processGO:00430652170.019
regulation of kinase activityGO:00435492490.019
sodium ion export from cellGO:003637610.019
cellular macromolecule catabolic processGO:00442652060.019
organic acid transportGO:00158491010.019
defecationGO:003042110.019
negative regulation of nervous system developmentGO:00519611560.019
negative regulation of cellular component organizationGO:00511291940.019
regulation of homeostatic processGO:00328441820.019
ribose phosphate metabolic processGO:00196932910.019
protein maturationGO:00516041760.019
muscle system processGO:00030121410.019
ribonucleoside triphosphate catabolic processGO:00092031990.018
positive regulation of protein kinase activityGO:00458601440.018
glycosyl compound metabolic processGO:19016572460.018
regulation of cell projection organizationGO:00313442060.018
transmission of nerve impulseGO:0019226760.018
regulation of ion transmembrane transportGO:00347651190.018
dephosphorylationGO:00163111290.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
positive regulation of programmed cell deathGO:00430682180.018
negative regulation of cell developmentGO:00107211690.018
neuron apoptotic processGO:00514021420.018
positive regulation of cell deathGO:00109422240.018
regulation of neuron differentiationGO:00456642810.018
regulation of muscle system processGO:0090257800.018
nucleotide catabolic processGO:00091662170.018
axon ensheathmentGO:0008366760.018
regulation of cell motilityGO:20001452360.018
regulation of protein kinase activityGO:00458592320.018
regulation of cell cycleGO:00517262810.017
regulation of secretionGO:00510462740.017
synapse organizationGO:00508081250.017
protein polymerizationGO:0051258570.017
epithelial tube formationGO:00721751300.017
positive regulation of cell developmentGO:00107202370.017
purine ribonucleoside triphosphate catabolic processGO:00092071990.017
regulation of heart contractionGO:0008016770.017
regulation of sodium ion transmembrane transportGO:190230590.017
sequestering of metal ionGO:0051238190.017
myosin filament organizationGO:003103330.017
purine ribonucleotide metabolic processGO:00091502900.017
purine nucleoside catabolic processGO:00061522050.017
small gtpase mediated signal transductionGO:0007264970.017
regulation of cellular catabolic processGO:00313292420.016
regulation of hormone levelsGO:00108172110.016
purine containing compound catabolic processGO:00725232130.016
positive regulation of potassium ion transportGO:004326830.016
regulation of hydrolase activityGO:00513362460.016
nucleoside triphosphate metabolic processGO:00091412300.016
myeloid cell differentiationGO:00300992330.016
establishment of synaptic vesicle localizationGO:0097480570.016
myotube differentiationGO:00149021050.016
negative regulation of immune system processGO:00026832090.016
cellular response to organonitrogen compoundGO:00714171450.016
nucleoside monophosphate metabolic processGO:0009123850.016
regulation of purine nucleotide catabolic processGO:00331211220.016
cell substrate adhesionGO:00315891300.016
morphogenesis of a branching epitheliumGO:00611381930.016
ribonucleoside monophosphate metabolic processGO:0009161800.016
regulation of transporter activityGO:0032409570.016
central nervous system neuron differentiationGO:00219531620.016
sodium ion transportGO:0006814730.016
calcium ion transportGO:00068161590.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
intracellular mrna localizationGO:000829840.015
regulation of ion homeostasisGO:2000021640.015
regulation of cell activationGO:00508652890.015
purine ribonucleotide catabolic processGO:00091542080.015
regulation of nucleoside metabolic processGO:00091181300.015
organonitrogen compound catabolic processGO:19015652640.015
axonogenesisGO:00074092740.015
heterocycle catabolic processGO:00467002800.015
morphogenesis of a branching structureGO:00017632030.015
bone developmentGO:00603481200.015
renal system developmentGO:00720012250.015
calcium ion transmembrane transportGO:0070588850.015
purine nucleoside metabolic processGO:00422782410.015
cytoplasmic transportGO:00164822340.015
kidney morphogenesisGO:0060993830.015
positive regulation of organelle organizationGO:00106381280.015
neuron deathGO:00709971540.015
purine nucleoside monophosphate metabolic processGO:0009126810.015
maintenance of locationGO:0051235890.015
tube formationGO:00351481400.015
ubiquitin dependent protein catabolic processGO:00065111290.014
proteolysis involved in cellular protein catabolic processGO:00516031470.014
response to acid chemicalGO:00011011110.014
establishment of vesicle localizationGO:0051650810.014
muscle fiber developmentGO:0048747760.014
ear morphogenesisGO:00424711180.014
positive regulation of sodium ion transmembrane transportGO:190230740.014
lymphocyte differentiationGO:00300982420.014
germ cell developmentGO:00072811850.014
divalent inorganic cation homeostasisGO:00725071380.014
regulation of muscle contractionGO:0006937490.014
heart contractionGO:0060047930.014
cellular carbohydrate metabolic processGO:00442621190.014
regulation of mapk cascadeGO:00434082480.014
single fertilizationGO:0007338820.014
regulation of neuron deathGO:19012141340.014
adult locomotory behaviorGO:0008344910.014
cellular response to organic cyclic compoundGO:0071407870.014
nucleoside catabolic processGO:00091642060.014
membrane depolarizationGO:0051899640.014
organelle localizationGO:00516401790.014
positive regulation of cellular component biogenesisGO:0044089940.014
skeletal system morphogenesisGO:00487052030.014
myelinationGO:0042552740.014
circulatory system processGO:00030131970.014
nucleoside triphosphate catabolic processGO:00091432050.014
organelle fissionGO:00482851700.014
dicarboxylic acid transportGO:0006835290.014
cofactor biosynthetic processGO:0051188410.014
vesicle localizationGO:0051648860.013
regulation of protein localizationGO:00328802310.013
regulation of neuron apoptotic processGO:00435231220.013
regulation of intracellular transportGO:00323861590.013
carbohydrate metabolic processGO:00059752300.013
protein modification by small protein conjugation or removalGO:00706472070.013
purine ribonucleoside catabolic processGO:00461302050.013
blood vessel morphogenesisGO:00485142850.013
wnt signaling pathwayGO:00160551880.013
regulation of body fluid levelsGO:00508781620.013
cellular response to acid chemicalGO:0071229680.013
organ growthGO:00352651170.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
ear developmentGO:00435832000.013
ribonucleoside catabolic processGO:00424542060.013
neurotransmitter secretionGO:0007269620.013
protein modification by small protein conjugationGO:00324461870.013
regulation of cell migrationGO:00303342190.013
potassium ion importGO:001010710.013
establishment of organelle localizationGO:00516561220.013
embryonic epithelial tube formationGO:00018381300.013
connective tissue developmentGO:00614481790.013
regulation of nucleotide metabolic processGO:00061401690.013
digestive tract morphogenesisGO:00485461470.013
modification dependent protein catabolic processGO:00199411330.013
rna interferenceGO:001624620.013
ossificationGO:00015032160.013
t cell activationGO:00421102890.013
peptide transportGO:00158331330.013
regulation of actin filament lengthGO:0030832450.012
cellular response to hormone stimulusGO:00328701500.012
monosaccharide metabolic processGO:00059961060.012
regulation of cell cycle processGO:00105641600.012
neural tube developmentGO:00219151600.012
mrna metabolic processGO:0016071840.012
rna processingGO:00063961050.012
synaptic vesicle transportGO:0048489570.012
respiratory tube developmentGO:00303231670.012
morphogenesis of embryonic epitheliumGO:00163311590.012
bone morphogenesisGO:0060349780.012
regulation of transferase activityGO:00513382630.012
negative regulation of cellular amine metabolic processGO:003323910.012
regulation of striated muscle cell differentiationGO:0051153810.012
glycerophospholipid metabolic processGO:0006650710.012
female gamete generationGO:0007292740.012
organophosphate ester transportGO:0015748280.012
respiratory system developmentGO:00605411900.012
calcium ion homeostasisGO:00550741270.012
forebrain developmentGO:00309003020.012
lipid localizationGO:00108761260.012
regulation of neuron projection developmentGO:00109751690.012
response to radiationGO:00093141650.012
protein localization to organelleGO:00333651850.012
amide transportGO:00428861380.012
protein processingGO:00164851630.012
regulation of proteolysisGO:00301621640.012
camera type eye developmentGO:00430102660.012
establishment of protein localization to membraneGO:0090150540.012
negative regulation of organelle organizationGO:0010639900.012
regulation of response to woundingGO:19030341890.012
regulation of multi organism processGO:00439001110.011
regulation of myeloid cell differentiationGO:0045637960.011
intracellular protein transportGO:00068862040.011
mitotic cell cycle processGO:19030471590.011
response to organic cyclic compoundGO:00140701980.011
regulation of lipid metabolic processGO:00192161180.011
regulation of establishment of protein localizationGO:00702011810.011
negative regulation of phosphorylationGO:00423261660.011
defense response to other organismGO:00985421970.011
protein ubiquitinationGO:00165671710.011
multi multicellular organism processGO:00447061090.011
regionalizationGO:00030023370.011
actin polymerization or depolymerizationGO:0008154540.011
mitochondrion organizationGO:00070051340.011
actomyosin structure organizationGO:0031032560.011
negative regulation of molecular functionGO:00440922580.011
wound healingGO:00420601570.011
negative regulation of synapse assemblyGO:005196430.011
response to organonitrogen compoundGO:00102432460.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
negative regulation of cell proliferationGO:00082852960.011
cellular metal ion homeostasisGO:00068751510.011
meiotic cell cycleGO:00513211220.011
lung developmentGO:00303241640.011
synapse assemblyGO:0007416560.011
multicellular organism growthGO:00352641610.011
microtubule based processGO:00070172360.011
compound eye developmentGO:004874910.011
atp metabolic processGO:0046034750.011
stem cell differentiationGO:00488632680.011
modification dependent macromolecule catabolic processGO:00436321330.011
lateral inhibitionGO:004633110.011
positive regulation of nucleotide metabolic processGO:00459811140.011
response to growth factorGO:00708481980.011
monovalent inorganic cation homeostasisGO:0055067330.011
development of primary sexual characteristicsGO:00451371430.011
canonical wnt signaling pathwayGO:00600701300.011
myeloid leukocyte differentiationGO:00025731190.011
developmental growth involved in morphogenesisGO:00605601380.011
development of primary male sexual characteristicsGO:0046546880.011
regulation of ras gtpase activityGO:0032318880.011
nucleocytoplasmic transportGO:00069131390.010
rac protein signal transductionGO:0016601130.010
protein targetingGO:00066051430.010
gland developmentGO:00487323300.010
fast calcium ion dependent exocytosis of neurotransmitterGO:009874610.010
response to oxidative stressGO:00069791230.010
negative regulation of apoptotic signaling pathwayGO:20012341040.010
protein homooligomerizationGO:0051260430.010
pharynx developmentGO:006046510.010
negative regulation of protein metabolic processGO:00512482820.010
reactive oxygen species metabolic processGO:0072593840.010
positive regulation of cytoskeleton organizationGO:0051495490.010
ribonucleoside monophosphate catabolic processGO:0009158570.010
kidney developmentGO:00018222130.010
regulation of nucleotide catabolic processGO:00308111220.010
tube closureGO:0060606910.010
regulation of ovulationGO:006027830.010
regulation of vesicle mediated transportGO:00606271390.010
homeostasis of number of cellsGO:00488722100.010

Fndc5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
musculoskeletal system diseaseDOID:1700.034
muscle tissue diseaseDOID:6600.034
muscular diseaseDOID:008000000.034
nervous system diseaseDOID:86300.029
central nervous system diseaseDOID:33100.028
cardiovascular system diseaseDOID:128700.026
myopathyDOID:42300.014
brain diseaseDOID:93600.014
heart diseaseDOID:11400.013
intrinsic cardiomyopathyDOID:006003600.013
cardiomyopathyDOID:005070000.013
cancerDOID:16200.011
organ system cancerDOID:005068600.011
disease of cellular proliferationDOID:1456600.011