Mus musculus

66 known processes

Xrcc5

X-ray repair complementing defective repair in Chinese hamster cells 5

(Aliases: AI314015,Ku80,Ku86)

Xrcc5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742070.555
covalent chromatin modificationGO:00165691630.440
histone modificationGO:00165701590.337
chromatin modificationGO:00165681870.276
chromatin organizationGO:00063252060.244
regionalizationGO:00030023370.243
dna metabolic processGO:00062593030.241
peptidyl amino acid modificationGO:00181933360.205
cellular amino acid metabolic processGO:00065201030.183
organelle assemblyGO:00709251770.182
dna repairGO:00062811070.179
double strand break repairGO:0006302480.167
positive regulation of cellular amino acid metabolic processGO:004576430.134
amine metabolic processGO:0009308450.131
leukocyte activation involved in immune responseGO:00023661260.127
organic cyclic compound catabolic processGO:19013612950.126
regulation of mitotic cell cycleGO:00073461260.123
regulation of cell cycleGO:00517262810.122
purine nucleotide metabolic processGO:00061633020.119
mitotic cell cycleGO:00002781950.118
regulation of cellular amino acid metabolic processGO:000652150.117
cellular amine metabolic processGO:0044106440.115
nucleoside triphosphate metabolic processGO:00091412300.115
cellular ketone metabolic processGO:0042180840.114
heterocycle catabolic processGO:00467002800.114
nucleoside monophosphate metabolic processGO:0009123850.112
ribonucleotide metabolic processGO:00092592910.109
apoptotic signaling pathwayGO:00971903060.109
Zebrafish
cell fate commitmentGO:00451652100.108
methylationGO:00322591340.104
intrinsic apoptotic signaling pathwayGO:00971931320.102
Zebrafish
regulation of cellular ketone metabolic processGO:0010565660.098
regulation of cell cycle processGO:00105641600.091
ribonucleoside triphosphate metabolic processGO:00091992200.089
somatic cell dna recombinationGO:0016444510.087
atp metabolic processGO:0046034750.084
regulation of mitotic cell cycle phase transitionGO:1901990730.084
regulation of cellular amine metabolic processGO:0033238200.084
ribose phosphate metabolic processGO:00196932910.083
macromolecule catabolic processGO:00090572810.083
production of molecular mediator of immune responseGO:00024401030.081
anatomical structure homeostasisGO:00602491450.081
peptidyl lysine modificationGO:0018205770.080
somatic diversification of immune receptorsGO:0002200530.076
purine ribonucleotide metabolic processGO:00091502900.075
purine containing compound metabolic processGO:00725213110.074
germ cell developmentGO:00072811850.074
cellular macromolecule catabolic processGO:00442652060.073
skeletal system developmentGO:00015013560.072
rna phosphodiester bond hydrolysisGO:0090501190.072
b cell activationGO:00421131610.072
immune effector processGO:00022523210.069
glycosyl compound metabolic processGO:19016572460.068
nucleobase containing small molecule metabolic processGO:00550863520.064
cellular nitrogen compound catabolic processGO:00442702800.063
stem cell differentiationGO:00488632680.062
positive regulation of protein phosphorylationGO:00019342420.060
signal transduction by p53 class mediatorGO:0072331510.060
Zebrafish
negative regulation of mitotic cell cycle phase transitionGO:1901991450.059
regulation of cell cycle phase transitionGO:1901987770.058
leukocyte differentiationGO:00025213420.056
positive regulation of cellular amine metabolic processGO:003324050.056
positive regulation of protein modification processGO:00314012990.056
nucleoside phosphate metabolic processGO:00067533380.055
ribonucleoside monophosphate metabolic processGO:0009161800.055
lymphocyte mediated immunityGO:00024491390.054
microtubule based processGO:00070172360.054
carbohydrate derivative catabolic processGO:19011362310.052
protein modification by small protein conjugation or removalGO:00706472070.052
mitotic cell cycle processGO:19030471590.052
rna processingGO:00063961050.052
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.050
regulation of organelle organizationGO:00330432890.049
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.049
nucleotide metabolic processGO:00091173320.049
purine nucleoside triphosphate metabolic processGO:00091442260.048
microtubule cytoskeleton organizationGO:00002261570.047
glycosyl compound catabolic processGO:19016582060.045
ribonucleoside metabolic processGO:00091192450.045
adaptive immune responseGO:00022501550.045
organophosphate catabolic processGO:00464342320.045
dna recombinationGO:0006310920.044
immunoglobulin mediated immune responseGO:0016064690.044
organelle fissionGO:00482851700.044
regulation of transferase activityGO:00513382630.044
negative regulation of dna replicationGO:000815640.044
purine ribonucleoside monophosphate metabolic processGO:0009167800.044
cell activation involved in immune responseGO:00022631260.043
digestive system developmentGO:00551232000.043
aromatic compound catabolic processGO:00194392860.043
camera type eye developmentGO:00430102660.042
nucleic acid phosphodiester bond hydrolysisGO:0090305490.042
lymphocyte activation involved in immune responseGO:0002285930.042
leukocyte mediated immunityGO:00024431740.042
ribonucleotide catabolic processGO:00092612080.042
purine ribonucleoside metabolic processGO:00461282410.041
purine ribonucleoside triphosphate metabolic processGO:00092052200.041
myeloid cell differentiationGO:00300992330.040
epithelial cell proliferationGO:00506731740.040
purine ribonucleoside catabolic processGO:00461302050.039
b cell activation involved in immune responseGO:0002312500.039
stem cell developmentGO:00488642190.039
telomere cappingGO:001623340.039
regulation of leukocyte differentiationGO:19021051590.039
cellular response to lipidGO:00713961450.039
nucleotide catabolic processGO:00091662170.039
protein modification by small protein conjugationGO:00324461870.038
organonitrogen compound catabolic processGO:19015652640.038
modification dependent macromolecule catabolic processGO:00436321330.038
digestive tract developmentGO:00485651900.038
histone acetylationGO:0016573410.038
regulation of chromosome organizationGO:0033044830.037
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.037
purine containing compound catabolic processGO:00725232130.037
purine nucleoside triphosphate catabolic processGO:00091462030.036
lateral inhibitionGO:004633110.036
gonad developmentGO:00084061410.036
negative regulation of apoptotic signaling pathwayGO:20012341040.036
purine nucleoside metabolic processGO:00422782410.036
protein acylationGO:0043543640.035
glial cell differentiationGO:00100011310.035
nucleoside phosphate catabolic processGO:19012922220.034
embryonic organ morphogenesisGO:00485622760.034
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.034
negative regulation of cell proliferationGO:00082852960.033
cell divisionGO:00513011200.033
regulation of kinase activityGO:00435492490.033
nuclear divisionGO:00002801580.033
purine ribonucleotide catabolic processGO:00091542080.032
ribonucleoside catabolic processGO:00424542060.032
response to organic cyclic compoundGO:00140701980.032
respiratory tube developmentGO:00303231670.032
multicellular organismal homeostasisGO:00488711640.032
purine nucleoside monophosphate metabolic processGO:0009126810.032
cell type specific apoptotic processGO:00972852680.032
neuron apoptotic processGO:00514021420.032
purine ribonucleoside triphosphate catabolic processGO:00092071990.031
maintenance of locationGO:0051235890.031
t cell differentiationGO:00302171740.031
purine nucleotide catabolic processGO:00061952110.031
wnt signaling pathwayGO:00160551880.031
b cell mediated immunityGO:0019724710.031
somatic diversification of immunoglobulinsGO:0016445430.031
macromolecule methylationGO:00434141200.030
internal protein amino acid acetylationGO:0006475420.030
regulation of epithelial cell proliferationGO:00506781410.030
negative regulation of intracellular signal transductionGO:19025321670.030
regulation of hydrolase activityGO:00513362460.030
dna conformation changeGO:0071103370.030
regulation of protein kinase activityGO:00458592320.029
neural tube formationGO:00018411080.029
spermatogenesisGO:00072832840.029
muscle cell differentiationGO:00426922610.029
myeloid leukocyte differentiationGO:00025731190.029
negative regulation of molecular functionGO:00440922580.028
response to acid chemicalGO:00011011110.028
skeletal muscle organ developmentGO:00605381630.028
epithelial tube morphogenesisGO:00605623030.028
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.028
cellular response to oxidative stressGO:0034599760.028
regulation of cellular response to stressGO:00801351590.028
immunoglobulin productionGO:0002377730.028
t cell activationGO:00421102890.027
protein maturationGO:00516041760.027
sensory organ morphogenesisGO:00905962420.027
cell cycle checkpointGO:0000075470.026
lymphocyte differentiationGO:00300982420.026
t cell differentiation in thymusGO:0033077770.026
positive regulation of cell deathGO:00109422240.026
double strand break repair via nonhomologous end joiningGO:0006303100.026
Human
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.026
digestive tract morphogenesisGO:00485461470.025
negative regulation of cellular protein metabolic processGO:00322692470.025
gland developmentGO:00487323300.025
negative regulation of mitotic cell cycleGO:0045930580.025
response to oxidative stressGO:00069791230.025
appendage developmentGO:00487361660.025
positive regulation of kinase activityGO:00336741550.025
limb developmentGO:00601731660.024
response to inorganic substanceGO:0010035960.024
locomotory behaviorGO:00076261950.024
meiotic nuclear divisionGO:00071261150.024
renal system developmentGO:00720012250.024
ribonucleoside triphosphate catabolic processGO:00092031990.024
purine nucleoside catabolic processGO:00061522050.024
male gamete generationGO:00482322850.024
tube formationGO:00351481400.024
mrna processingGO:0006397630.024
regulation of membrane potentialGO:00423911920.024
isotype switchingGO:0045190360.023
response to reactive oxygen speciesGO:0000302560.023
homeostasis of number of cellsGO:00488722100.023
striated muscle tissue developmentGO:00147062930.023
response to organonitrogen compoundGO:00102432460.023
neural tube developmentGO:00219151600.023
regulation of neuron differentiationGO:00456642810.023
muscle cell developmentGO:00550011330.023
regulation of cell activationGO:00508652890.023
reactive oxygen species metabolic processGO:0072593840.023
positive regulation of growthGO:00459271040.023
peptidyl lysine acetylationGO:0018394450.023
nucleoside metabolic processGO:00091162460.022
chromosome segregationGO:0007059480.022
embryonic epithelial tube formationGO:00018381300.022
action potentialGO:0001508780.022
protein ubiquitinationGO:00165671710.022
inflammatory responseGO:00069542440.022
developmental maturationGO:00217001930.022
nucleotide excision repairGO:0006289130.022
forebrain developmentGO:00309003020.022
negative regulation of cellular amine metabolic processGO:003323910.022
nitrogen compound transportGO:00717052710.022
negative regulation of protein maturationGO:1903318790.022
negative regulation of immune system processGO:00026832090.022
cellular protein catabolic processGO:00442571550.022
non recombinational repairGO:0000726100.022
Human
protein catabolic processGO:00301632210.021
negative regulation of protein metabolic processGO:00512482820.021
regulation of apoptotic signaling pathwayGO:20012331970.021
segmentationGO:0035282930.021
muscle tissue developmentGO:00605373080.021
negative regulation of cell cycleGO:00457861230.021
nucleoside catabolic processGO:00091642060.021
urogenital system developmentGO:00016552610.021
cellular response to growth factor stimulusGO:00713631970.020
skeletal system morphogenesisGO:00487052030.020
cell cycle g1 s phase transitionGO:0044843570.020
cellular homeostasisGO:00197252400.020
telomere maintenance in response to dna damageGO:004324740.020
internal peptidyl lysine acetylationGO:0018393420.020
rna 3 end processingGO:0031123200.020
gastrulationGO:00073691160.020
regulation of cellular component biogenesisGO:00440871810.020
cytokine productionGO:00018163190.020
striated muscle cell developmentGO:00550021250.020
endomembrane system organizationGO:00102561470.020
dna damage checkpointGO:0000077260.019
regulation of body fluid levelsGO:00508781620.019
female gamete generationGO:0007292740.019
morphogenesis of embryonic epitheliumGO:00163311590.019
neuron deathGO:00709971540.019
regulation of neuron deathGO:19012141340.019
trna processingGO:0008033110.019
skeletal muscle cell differentiationGO:0035914660.019
positive regulation of transferase activityGO:00513471670.019
cellular protein complex assemblyGO:00436231160.019
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.019
Zebrafish
negative regulation of phosphate metabolic processGO:00459361840.019
telomere maintenanceGO:0000723190.019
carbohydrate derivative biosynthetic processGO:19011371830.018
cellular lipid metabolic processGO:00442553230.018
g1 s transition of mitotic cell cycleGO:0000082570.018
rhythmic processGO:00485111740.018
chemotaxisGO:00069352470.018
proteolysis involved in cellular protein catabolic processGO:00516031470.018
nucleoside monophosphate catabolic processGO:0009125590.018
peptidyl tyrosine phosphorylationGO:00181081430.018
gliogenesisGO:00420631410.018
ribonucleoside monophosphate catabolic processGO:0009158570.018
somatic recombination of immunoglobulin gene segmentsGO:0016447420.018
mrna metabolic processGO:0016071840.017
regulation of protein localizationGO:00328802310.017
positive regulation of nervous system developmentGO:00519622210.017
synapsisGO:0007129340.017
organonitrogen compound biosynthetic processGO:19015661920.017
mitochondrion organizationGO:00070051340.017
cytoplasmic transportGO:00164822340.017
protein dna complex subunit organizationGO:0071824280.017
ncrna processingGO:0034470260.017
regulation of sequence specific dna binding transcription factor activityGO:00510901060.017
neuronal action potentialGO:0019228540.017
fertilizationGO:00095661270.017
histone h2a ubiquitinationGO:003352230.017
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.017
hindbrain developmentGO:00309021280.017
positive regulation of programmed cell deathGO:00430682180.017
bone developmentGO:00603481200.017
regulation of reactive oxygen species metabolic processGO:2000377400.017
cell growthGO:00160491300.017
cellular component assembly involved in morphogenesisGO:00109271390.017
atp catabolic processGO:0006200550.017
circulatory system processGO:00030131970.017
regulation of cell projection organizationGO:00313442060.016
cation transportGO:00068123990.016
blastocyst developmentGO:0001824800.016
regulation of bindingGO:00510981110.016
nucleoside triphosphate catabolic processGO:00091432050.016
purine nucleoside monophosphate catabolic processGO:0009128580.016
g protein coupled receptor signaling pathwayGO:00071862430.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
intracellular protein transportGO:00068862040.016
determination of left right symmetryGO:0007368800.016
trna aminoacylationGO:004303910.016
hematopoietic progenitor cell differentiationGO:00022441430.016
protein alkylationGO:0008213810.016
protein localization to organelleGO:00333651850.016
response to retinoic acidGO:0032526560.016
positive regulation of cell developmentGO:00107202370.016
regulation of homeostatic processGO:00328441820.016
negative regulation of neuron deathGO:1901215980.015
regulation of cell morphogenesis involved in differentiationGO:00107691510.015
endocytosisGO:00068971680.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
nucleocytoplasmic transportGO:00069131390.015
regulation of neuron projection developmentGO:00109751690.015
negative regulation of protein modification processGO:00314001630.015
regulation of protein processingGO:0070613960.015
retina development in camera type eyeGO:00600411190.015
regulation of inflammatory responseGO:00507271470.015
gene silencingGO:0016458380.015
muscle system processGO:00030121410.015
negative regulation of neuron apoptotic processGO:0043524920.015
intracellular receptor signaling pathwayGO:0030522740.015
multicellular organism growthGO:00352641610.015
meiotic cell cycleGO:00513211220.015
regulation of proteolysisGO:00301621640.015
regulation of hormone levelsGO:00108172110.015
negative regulation of cellular component organizationGO:00511291940.015
regulation of cell migrationGO:00303342190.015
regulation of protein catabolic processGO:00421761080.015
regulation of lipid metabolic processGO:00192161180.015
regulation of establishment of protein localizationGO:00702011810.015
negative regulation of epithelial cell proliferationGO:0050680640.014
positive regulation of apoptotic processGO:00430652170.014
protein processingGO:00164851630.014
organelle localizationGO:00516401790.014
regulation of cell motilityGO:20001452360.014
regulation of protein maturationGO:1903317960.014
tissue homeostasisGO:00018941150.014
positive regulation of immature t cell proliferationGO:003309140.014
embryonic limb morphogenesisGO:00303261260.014
respiratory system developmentGO:00605411900.014
cell adhesionGO:00071553290.014
regulation of cell divisionGO:0051302760.014
nuclear transportGO:00511691390.014
response to lipopolysaccharideGO:00324961280.014
regulation of lymphocyte activationGO:00512492400.014
histone lysine methylationGO:0034968500.014
regulation of chromatin modificationGO:1903308570.014
rna phosphodiester bond hydrolysis exonucleolyticGO:009050340.014
transmission of nerve impulseGO:0019226760.014
wound healingGO:00420601570.014
regulation of cellular catabolic processGO:00313292420.014
response to radiationGO:00093141650.014
Zebrafish
regulation of cellular response to growth factor stimulusGO:0090287820.014
trna aminoacylation for protein translationGO:000641810.013
limb morphogenesisGO:00351081490.013
dna integrity checkpointGO:0031570280.013
sensory perceptionGO:00076002450.013
stem cell maintenanceGO:00198271300.013
regulation of nuclear divisionGO:0051783560.013
histone methylationGO:0016571710.013
negative regulation of phosphorus metabolic processGO:00105631840.013
development of primary sexual characteristicsGO:00451371430.013
endoderm developmentGO:0007492450.013
regulation of neuron apoptotic processGO:00435231220.013
blood circulationGO:00080151950.013
positive regulation of mapk cascadeGO:00434101700.013
meiosis iGO:0007127600.013
response to growth factorGO:00708481980.013
notch signaling pathwayGO:0007219710.013
response to peptideGO:19016521360.013
skin developmentGO:00435882200.013
cellular response to acid chemicalGO:0071229680.013
cell maturationGO:00484691270.013
appendage morphogenesisGO:00351071490.013
dna replicationGO:0006260520.012
leukocyte proliferationGO:00706611720.012
modification dependent protein catabolic processGO:00199411330.012
regulation of defense responseGO:00313472330.012
developmental growth involved in morphogenesisGO:00605601380.012
negative regulation of cell cycle phase transitionGO:1901988480.012
regulation of myeloid cell differentiationGO:0045637960.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
regulation of secretion by cellGO:19035302490.012
protein methylationGO:0006479810.012
epithelial tube formationGO:00721751300.012
negative regulation of myeloid cell differentiationGO:0045638380.012
regulation of striated muscle cell differentiationGO:0051153810.012
epidermis developmentGO:00085441870.012
negative regulation of phosphorylationGO:00423261660.012
regulation of t cell activationGO:00508631700.012
positive regulation of chromosome organizationGO:2001252330.012
establishment of organelle localizationGO:00516561220.012
negative regulation of protein processingGO:0010955790.011
embryonic digit morphogenesisGO:0042733560.011
positive regulation of mitotic cell cycle phase transitionGO:1901992170.011
regulation of lymphocyte differentiationGO:00456191070.011
maintenance of protein location in nucleusGO:005145720.011
regulation of chromatin organizationGO:1902275570.011
small molecule biosynthetic processGO:00442831320.011
regulation of histone modificationGO:0031056560.011
heart morphogenesisGO:00030071780.011
protection from non homologous end joining at telomereGO:003184840.011
regulation of protein localization to nucleusGO:1900180600.011
protein secretionGO:00093061110.011
axonogenesisGO:00074092740.011
positive regulation of hydrolase activityGO:00513451480.011
regulation of cytokine productionGO:00018172660.011
alcohol metabolic processGO:00060661160.011
divalent inorganic cation transportGO:00725111780.011
purine ribonucleoside monophosphate catabolic processGO:0009169570.011
ensheathment of neuronsGO:0007272760.011
peptidyl tyrosine modificationGO:00182121450.011
peptidyl serine modificationGO:0018209830.011
negative regulation of organelle organizationGO:0010639900.011
proteasomal protein catabolic processGO:0010498980.011
regulation of protein transportGO:00512231630.011
oogenesisGO:0048477560.011
tube closureGO:0060606910.011
regulation of response to woundingGO:19030341890.011
connective tissue developmentGO:00614481790.011
regulation of multi organism processGO:00439001110.010
response to oxygen levelsGO:0070482620.010
protein localization to nucleusGO:00345041210.010
neuromuscular processGO:0050905990.010
negative regulation of leukocyte differentiationGO:1902106510.010
mapk cascadeGO:00001652810.010
myelinationGO:0042552740.010
trna metabolic processGO:0006399110.010
organic hydroxy compound metabolic processGO:19016152030.010
blood vessel morphogenesisGO:00485142850.010
positive regulation of dna templated transcription elongationGO:003278620.010
positive regulation of cell activationGO:00508671580.010
embryonic appendage morphogenesisGO:00351131260.010
regulation of ion transportGO:00432692150.010
regulation of transmembrane transportGO:00347621280.010
mrna 3 end processingGO:0031124160.010
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.010

Xrcc5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
nervous system diseaseDOID:86300.024
disease of cellular proliferationDOID:1456600.023
organ system cancerDOID:005068600.023
cancerDOID:16200.023
eye and adnexa diseaseDOID:149200.019
sensory system diseaseDOID:005015500.019
eye diseaseDOID:561400.019
immune system cancerDOID:006008300.018
hematologic cancerDOID:253100.018
musculoskeletal system diseaseDOID:1700.011