Mus musculus

84 known processes

Pfkm

phosphofructokinase, muscle

(Aliases: PFK-A,Pfkx,AI131669,PFK-M,Pfk4,Pfk-4,Pfka)

Pfkm biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550854120.183
positive regulation of cell deathGO:00109422240.151
carbohydrate metabolic processGO:00059752300.123
energy derivation by oxidation of organic compoundsGO:0015980770.113
glycosyl compound catabolic processGO:19016582060.112
nucleotide metabolic processGO:00091173320.096
nucleobase containing small molecule metabolic processGO:00550863520.094
nucleoside phosphate metabolic processGO:00067533380.092
ribose phosphate metabolic processGO:00196932910.089
purine nucleoside metabolic processGO:00422782410.087
cardiac muscle contractionGO:0060048320.085
purine ribonucleotide metabolic processGO:00091502900.083
ribonucleotide metabolic processGO:00092592910.082
microtubule based processGO:00070172360.081
nucleoside metabolic processGO:00091162460.080
oxidation reduction processGO:00551143420.079
generation of precursor metabolites and energyGO:00060911030.077
positive regulation of programmed cell deathGO:00430682180.070
cellular amino acid metabolic processGO:00065201030.069
cation transportGO:00068123990.066
macromolecule catabolic processGO:00090572810.065
intracellular protein transportGO:00068862040.065
organonitrogen compound catabolic processGO:19015652640.063
response to organonitrogen compoundGO:00102432460.063
protein glycosylationGO:0006486550.060
purine nucleoside catabolic processGO:00061522050.060
pyruvate metabolic processGO:0006090280.059
regulation of protein localizationGO:00328802310.059
regulation of transmembrane transportGO:00347621280.059
purine ribonucleoside triphosphate catabolic processGO:00092071990.058
positive regulation of cellular amine metabolic processGO:003324050.055
regulation of neuron projection developmentGO:00109751690.055
carbohydrate catabolic processGO:0016052320.054
peptidyl amino acid modificationGO:00181933360.054
purine nucleoside triphosphate metabolic processGO:00091442260.052
cellular homeostasisGO:00197252400.052
nucleoside triphosphate metabolic processGO:00091412300.051
inorganic ion transmembrane transportGO:00986602340.051
positive regulation of apoptotic processGO:00430652170.051
lipid biosynthetic processGO:00086101790.051
purine ribonucleoside metabolic processGO:00461282410.050
heterocycle catabolic processGO:00467002800.049
regulation of establishment of protein localizationGO:00702011810.048
carbohydrate derivative catabolic processGO:19011362310.048
purine nucleotide metabolic processGO:00061633020.048
anatomical structure homeostasisGO:00602491450.047
carbohydrate derivative biosynthetic processGO:19011371830.047
ribonucleoside triphosphate catabolic processGO:00092031990.046
inorganic cation transmembrane transportGO:00986622070.046
aromatic compound catabolic processGO:00194392860.046
glycosyl compound metabolic processGO:19016572460.046
cellular component assembly involved in morphogenesisGO:00109271390.045
muscle contractionGO:00069361010.045
actin cytoskeleton organizationGO:00300362200.045
muscle cell differentiationGO:00426922610.044
nucleoside triphosphate catabolic processGO:00091432050.044
regulation of synaptic growth at neuromuscular junctionGO:000858240.043
ribonucleoside catabolic processGO:00424542060.043
cellular lipid metabolic processGO:00442553230.042
cellular amine metabolic processGO:0044106440.042
striated muscle tissue developmentGO:00147062930.042
organophosphate catabolic processGO:00464342320.041
cellular ketone metabolic processGO:0042180840.040
nucleotide catabolic processGO:00091662170.040
chemotaxisGO:00069352470.040
amine metabolic processGO:0009308450.040
cellular nitrogen compound catabolic processGO:00442702800.040
homeostasis of number of cellsGO:00488722100.039
organelle assemblyGO:00709251770.039
cofactor metabolic processGO:0051186800.039
regulation of cellular amino acid metabolic processGO:000652150.039
microtubule cytoskeleton organizationGO:00002261570.038
coenzyme metabolic processGO:0006732520.038
sensory organ morphogenesisGO:00905962420.038
axonogenesisGO:00074092740.038
organonitrogen compound biosynthetic processGO:19015661920.038
cellular carbohydrate metabolic processGO:00442621190.038
purine containing compound metabolic processGO:00725213110.038
protein localization to organelleGO:00333651850.037
purine nucleotide catabolic processGO:00061952110.037
purine containing compound catabolic processGO:00725232130.037
regulation of cellular ketone metabolic processGO:0010565660.036
nucleoside phosphate catabolic processGO:19012922220.036
muscle cell developmentGO:00550011330.036
regulation of organelle organizationGO:00330432890.036
negative regulation of cell proliferationGO:00082852960.035
regulation of apoptotic signaling pathwayGO:20012331970.035
endocytosisGO:00068971680.035
ribonucleoside metabolic processGO:00091192450.034
regulation of cellular amine metabolic processGO:0033238200.034
muscle tissue developmentGO:00605373080.033
membrane organizationGO:00610242450.033
substantia nigra developmentGO:002176220.033
purine ribonucleoside triphosphate metabolic processGO:00092052200.033
oocyte axis specificationGO:000730920.033
guanosine containing compound metabolic processGO:19010681440.033
establishment of vesicle localizationGO:0051650810.032
cation transmembrane transportGO:00986552660.032
monocarboxylic acid metabolic processGO:00327871910.032
apoptotic signaling pathwayGO:00971903060.032
purine ribonucleoside catabolic processGO:00461302050.032
heart contractionGO:0060047930.032
protein catabolic processGO:00301632210.031
organic cyclic compound catabolic processGO:19013612950.031
muscle system processGO:00030121410.031
purine nucleoside triphosphate catabolic processGO:00091462030.031
organic acid biosynthetic processGO:0016053860.031
dephosphorylationGO:00163111290.030
synaptic transmissionGO:00072683290.030
learning or memoryGO:00076111480.030
purine ribonucleotide catabolic processGO:00091542080.030
protein localization to nucleusGO:00345041210.030
organophosphate biosynthetic processGO:00904071220.030
mitotic cell cycleGO:00002781950.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
regulation of system processGO:00440572000.029
regulation of intracellular protein transportGO:0033157820.029
cellular response to dna damage stimulusGO:00069742070.029
cation homeostasisGO:00550802120.029
phosphatidic acid biosynthetic processGO:000665420.029
neuron projection guidanceGO:00974851410.029
male gamete generationGO:00482322850.028
dna metabolic processGO:00062593030.028
regulation of membrane potentialGO:00423911920.028
ion transmembrane transportGO:00342203610.028
regulation of cellular component biogenesisGO:00440871810.028
negative regulation of cell cycleGO:00457861230.028
synaptic vesicle localizationGO:0097479590.027
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.027
vegf activated neuropilin signaling pathwayGO:003819020.027
regulation of cell morphogenesis involved in differentiationGO:00107691510.027
rho protein signal transductionGO:0007266320.026
regulation of protein transportGO:00512231630.026
regulation of ion transportGO:00432692150.026
regulation of neuron differentiationGO:00456642810.026
regulation of cellular component sizeGO:00325351210.026
regulation of cell projection organizationGO:00313442060.025
cellular ion homeostasisGO:00068731650.025
myeloid cell homeostasisGO:00022621140.025
cellular polysaccharide catabolic processGO:004424750.025
ras protein signal transductionGO:0007265770.025
cellular glucan metabolic processGO:0006073320.025
regulation of polyamine transmembrane transportGO:190226750.024
establishment or maintenance of cytoskeleton polarityGO:003095220.024
regulation of intracellular transportGO:00323861590.024
response to insulinGO:00328681000.024
cellular chemical homeostasisGO:00550822150.024
cytoplasmic transportGO:00164822340.024
sodium ion exportGO:007143620.024
regulation of ion transmembrane transportGO:00347651190.024
regulation of homeostatic processGO:00328441820.024
regulation of cellular catabolic processGO:00313292420.024
negative regulation of cellular component organizationGO:00511291940.023
glycerolipid metabolic processGO:00464861220.023
cellular response to organonitrogen compoundGO:00714171450.023
organelle fissionGO:00482851700.023
cognitionGO:00508901490.023
ribonucleoside monophosphate metabolic processGO:0009161800.023
small gtpase mediated signal transductionGO:0007264970.023
striated muscle contractionGO:0006941450.023
negative regulation of molecular functionGO:00440922580.022
ribonucleoside triphosphate metabolic processGO:00091992200.022
purine ribonucleoside monophosphate metabolic processGO:0009167800.022
glycosylationGO:0070085620.022
acyl coa metabolic processGO:0006637190.022
vesicle localizationGO:0051648860.022
nuclear transportGO:00511691390.022
regulation of nucleoside metabolic processGO:00091181300.022
regulation of axon extensionGO:0030516430.021
sensory perceptionGO:00076002450.021
response to peptideGO:19016521360.021
oocyte constructionGO:000730820.021
ribonucleotide catabolic processGO:00092612080.021
pole plasm assemblyGO:000731520.021
cell growthGO:00160491300.021
positive regulation of organelle organizationGO:00106381280.021
chromatin organizationGO:00063252060.021
metencephalon developmentGO:0022037890.020
regulation of anatomical structure sizeGO:00900661780.020
heart morphogenesisGO:00030071780.020
establishment of organelle localizationGO:00516561220.020
sodium ion transportGO:0006814730.020
carbohydrate biosynthetic processGO:0016051740.020
striated muscle cell developmentGO:00550021250.020
organelle localizationGO:00516401790.020
adult behaviorGO:00305341350.020
cell type specific apoptotic processGO:00972852680.019
oocyte anterior posterior axis specificationGO:000731420.019
positive regulation of neuron projection developmentGO:0010976790.019
negative regulation of growthGO:0045926990.019
phospholipid biosynthetic processGO:0008654360.019
synaptic vesicle transportGO:0048489570.019
cell adhesionGO:00071553290.019
maintenance of locationGO:0051235890.019
regulation of cell cycleGO:00517262810.019
multicellular organismal homeostasisGO:00488711640.019
negative regulation of nervous system developmentGO:00519611560.019
meiotic cell cycleGO:00513211220.019
membrane lipid biosynthetic processGO:0046467320.019
developmental growth involved in morphogenesisGO:00605601380.019
nuclear divisionGO:00002801580.019
response to peptide hormoneGO:00434341270.019
positive regulation of transmembrane transportGO:0034764290.019
regulation of cytoplasmic transportGO:19036491120.019
spermatogenesisGO:00072832840.018
lateral inhibitionGO:004633110.018
muscle fiber developmentGO:0048747760.018
negative regulation of synapse assemblyGO:005196430.018
wound healingGO:00420601570.018
regulation of cell sizeGO:0008361720.018
nucleoside monophosphate metabolic processGO:0009123850.018
heart processGO:0003015940.018
mapk cascadeGO:00001652810.018
sodium ion export from cellGO:003637610.018
establishment of protein localization to organelleGO:00725941180.017
cell junction organizationGO:0034330770.017
male anatomical structure morphogenesisGO:009059840.017
renal system developmentGO:00720012250.017
alpha amino acid metabolic processGO:1901605590.017
circulatory system processGO:00030131970.017
divalent inorganic cation homeostasisGO:00725071380.017
nucleocytoplasmic transportGO:00069131390.017
eye photoreceptor cell differentiationGO:0001754410.017
regulation of purine nucleotide catabolic processGO:00331211220.017
negative regulation of intracellular signal transductionGO:19025321670.017
negative regulation of cell developmentGO:00107211690.017
cell maturationGO:00484691270.017
reactive oxygen species metabolic processGO:0072593840.017
sialylationGO:0097503140.017
spermatid differentiationGO:00485151150.017
cellular response to hormone stimulusGO:00328701500.017
cytokine productionGO:00018163190.017
glycoprotein biosynthetic processGO:0009101890.017
regulation of cell motilityGO:20001452360.017
action potentialGO:0001508780.017
glucose homeostasisGO:00425931280.017
myotube differentiationGO:00149021050.017
germ cell developmentGO:00072811850.017
small molecule catabolic processGO:0044282710.017
immune effector processGO:00022523210.017
positive regulation of intracellular transportGO:0032388700.017
morphogenesis of embryonic epitheliumGO:00163311590.017
transmission of nerve impulseGO:0019226760.016
cell divisionGO:00513011200.016
regulation of mitotic cell cycleGO:00073461260.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.016
myeloid cell differentiationGO:00300992330.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
intracellular mrna localizationGO:000829840.016
protein targetingGO:00066051430.016
response to oxygen levelsGO:0070482620.016
asymmetric neuroblast divisionGO:005505910.016
cofactor biosynthetic processGO:0051188410.016
divalent inorganic cation transportGO:00725111780.016
carbohydrate transportGO:0008643620.016
tissue homeostasisGO:00018941150.016
regulation of white fat cell proliferationGO:007035020.016
locomotory behaviorGO:00076261950.016
metal ion homeostasisGO:00550651890.016
negative regulation of phosphorus metabolic processGO:00105631840.016
developmental cell growthGO:0048588840.016
nucleoside catabolic processGO:00091642060.016
negative regulation of inclusion body assemblyGO:009008410.016
phosphatidic acid metabolic processGO:004647320.016
calcium ion transportGO:00068161590.016
neuron projection extensionGO:1990138640.015
synaptic vesicle recyclingGO:0036465190.015
establishment or maintenance of neuroblast polarityGO:004519610.015
establishment or maintenance of cell polarityGO:0007163860.015
glycoprotein metabolic processGO:00091001160.015
myeloid leukocyte differentiationGO:00025731190.015
guanosine containing compound catabolic processGO:19010691440.015
mitochondrion degradationGO:000042230.015
glycerolipid biosynthetic processGO:0045017500.015
glucan metabolic processGO:0044042320.015
maternal determination of anterior posterior axis embryoGO:000835820.015
multicellular organismal signalingGO:0035637910.015
thioester biosynthetic processGO:003538470.015
regulation of protein catabolic processGO:00421761080.015
neural precursor cell proliferationGO:00613511210.015
urogenital system developmentGO:00016552610.015
establishment of synaptic vesicle localizationGO:0097480570.015
male genitalia morphogenesisGO:004880840.015
regulation of cardiac muscle contraction by calcium ion signalingGO:001088290.015
mitotic cell cycle processGO:19030471590.015
negative regulation of cellular amine metabolic processGO:003323910.015
meiotic nuclear divisionGO:00071261150.015
positive regulation of sodium ion transmembrane transportGO:190230740.015
cellular macromolecule catabolic processGO:00442652060.015
myosin filament organizationGO:003103330.015
divalent metal ion transportGO:00708381720.014
cardiac muscle fiber developmentGO:004873940.014
hematopoietic progenitor cell differentiationGO:00022441430.014
glycerophospholipid metabolic processGO:0006650710.014
negative regulation of dna replicationGO:000815640.014
paracrine signalingGO:003800110.014
regulation of cytokine productionGO:00018172660.014
camera type eye developmentGO:00430102660.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
kidney developmentGO:00018222130.014
cellular carbohydrate catabolic processGO:0044275150.014
anion transportGO:00068201770.014
glucose transportGO:0015758560.014
regulation of ras protein signal transductionGO:00465781140.014
cardiac muscle tissue developmentGO:00487381300.014
axon guidanceGO:00074111410.014
response to metal ionGO:0010038470.014
myeloid leukocyte migrationGO:0097529570.014
macromolecule glycosylationGO:0043413550.014
angiogenesisGO:00015252010.014
blood vessel morphogenesisGO:00485142850.014
cellular calcium ion homeostasisGO:00068741190.014
respiratory system developmentGO:00605411900.014
negative regulation of phosphate metabolic processGO:00459361840.014
skeletal muscle organ developmentGO:00605381630.014
inclusion body assemblyGO:007084130.014
atp metabolic processGO:0046034750.013
sulfur compound biosynthetic processGO:0044272370.013
regulation of purine nucleotide metabolic processGO:19005421690.013
connective tissue developmentGO:00614481790.013
polysaccharide metabolic processGO:0005976390.013
regulation of neurotransmitter levelsGO:0001505870.013
response to extracellular stimulusGO:00099911270.013
regulation of nucleotide metabolic processGO:00061401690.013
monosaccharide transportGO:0015749580.013
cellular respirationGO:0045333380.013
calcium ion homeostasisGO:00550741270.013
microtubule based movementGO:0007018840.013
regulation of secretionGO:00510462740.013
phospholipid metabolic processGO:0006644870.013
neuromuscular processGO:0050905990.013
extrinsic apoptotic signaling pathwayGO:00971911260.013
digestive system developmentGO:00551232000.013
positive regulation of nucleotide metabolic processGO:00459811140.013
pyridine containing compound catabolic processGO:007252640.013
mitochondrion organizationGO:00070051340.013
posttranscriptional regulation of gene expressionGO:00106081550.013
endomembrane system organizationGO:00102561470.013
glycogen metabolic processGO:0005977320.013
purine ribonucleoside monophosphate catabolic processGO:0009169570.013
photoreceptor cell developmentGO:0042461400.013
sequestering of metal ionGO:0051238190.013
cell cell junction organizationGO:0045216720.013
negative regulation of cellular protein metabolic processGO:00322692470.013
neuron neuron synaptic transmissionGO:0007270690.013
organic anion transportGO:00157111370.013
developmental maturationGO:00217001930.013
regulation of hydrolase activityGO:00513362460.013
positive regulation of protein export from nucleusGO:004682740.013
cerebellum developmentGO:0021549770.013
sulfur compound metabolic processGO:00067901000.013
glycolytic processGO:0006096200.013
leukocyte differentiationGO:00025213420.013
spermatid developmentGO:00072861080.012
regulation of metal ion transportGO:00109591060.012
response to inorganic substanceGO:0010035960.012
development of primary sexual characteristicsGO:00451371430.012
single organism cell adhesionGO:00986021560.012
purine nucleoside monophosphate metabolic processGO:0009126810.012
positive regulation of cell developmentGO:00107202370.012
female gamete generationGO:0007292740.012
response to acid chemicalGO:00011011110.012
blood circulationGO:00080151950.012
multicellular organism growthGO:00352641610.012
glycerophospholipid biosynthetic processGO:0046474320.012
establishment of protein localization to membraneGO:0090150540.012
regulation of response to woundingGO:19030341890.012
male courtship behaviorGO:000804920.012
rhythmic processGO:00485111740.012
skin developmentGO:00435882200.012
potassium ion transportGO:0006813520.012
peptidyl serine phosphorylationGO:0018105740.012
epithelial tube morphogenesisGO:00605623030.012
regulation of calcium ion transportGO:0051924690.012
alpha amino acid catabolic processGO:1901606180.012
regulation of secretion by cellGO:19035302490.012
protein localization to membraneGO:00726571080.012
hexose transportGO:0008645560.012
asymmetric stem cell divisionGO:009872230.012
mitochondrion distributionGO:004831140.012
sequestering of calcium ionGO:0051208180.012
response to organic cyclic compoundGO:00140701980.012
regulation of vesicle mediated transportGO:00606271390.012
morphogenesis of a branching structureGO:00017632030.011
regulation of muscle adaptationGO:0043502310.011
ribonucleoside monophosphate catabolic processGO:0009158570.011
regulation of cell migrationGO:00303342190.011
protein importGO:00170381010.011
regulation of protein kinase activityGO:00458592320.011
regulation of nucleotide catabolic processGO:00308111220.011
neuromuscular process controlling balanceGO:0050885590.011
forebrain developmentGO:00309003020.011
protein polymerizationGO:0051258570.011
metanephric glomerular endothelium developmentGO:007226410.011
mitochondrial membrane organizationGO:0007006260.011
regulation of multi organism processGO:00439001110.011
protein modification by small protein conjugation or removalGO:00706472070.011
positive regulation of fibroblast growth factor receptor signaling pathwayGO:004574330.011
cellular response to acid chemicalGO:0071229680.011
response to nutrient levelsGO:00316671090.011
regulation of transporter activityGO:0032409570.011
covalent chromatin modificationGO:00165691630.011
cardiac muscle cell developmentGO:0055013390.011
positive regulation of protein transportGO:0051222930.011
striated muscle myosin thick filament assemblyGO:007168810.011
sphingolipid biosynthetic processGO:0030148260.011
nuclear importGO:0051170950.011
negative regulation of neuron apoptotic processGO:0043524920.011
necrotic cell deathGO:0070265300.011
nitrogen compound transportGO:00717052710.011
energy reserve metabolic processGO:0006112390.011
monocarboxylic acid biosynthetic processGO:0072330610.011
anion transmembrane transportGO:0098656710.011
actin filament organizationGO:00070151130.011
calcium ion transmembrane transportGO:0070588850.011
cell junction assemblyGO:0034329520.011
inter male aggressive behaviorGO:000212130.011
regulation of extent of cell growthGO:0061387520.011
regulation of cell cycle processGO:00105641600.011
cellular modified amino acid biosynthetic processGO:0042398120.011
nucleoside monophosphate catabolic processGO:0009125590.011
regulation of feeding behaviorGO:006025930.010
dna repairGO:00062811070.010
synaptic vesicle endocytosisGO:0048488190.010
establishment of neuroblast polarityGO:004520010.010
cellularizationGO:000734910.010
regulation of cytoskeleton organizationGO:00514931220.010
cellular response to lipidGO:00713961450.010
regulation of sarcomere organizationGO:006029740.010
negative regulation of phosphorylationGO:00423261660.010
plasma membrane organizationGO:0007009900.010
atp catabolic processGO:0006200550.010
protein o linked glycosylationGO:0006493160.010
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.010
synapse organizationGO:00508081250.010
positive regulation of protein modification processGO:00314012990.010
negative regulation of cell growthGO:0030308440.010
negative regulation of organelle organizationGO:0010639900.010
regulation of skeletal muscle adaptationGO:0014733120.010

Pfkm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.109
disease of anatomical entityDOID:700.062
nervous system diseaseDOID:86300.062
central nervous system diseaseDOID:33100.044
immune system diseaseDOID:291400.032
inherited metabolic disorderDOID:65500.030
hematopoietic system diseaseDOID:7400.018
cardiovascular system diseaseDOID:128700.017
neurodegenerative diseaseDOID:128900.016
musculoskeletal system diseaseDOID:1700.012
carbohydrate metabolic disorderDOID:297800.012
muscle tissue diseaseDOID:6600.010
muscular diseaseDOID:008000000.010