Mus musculus

0 known processes

Leap2

liver-expressed antimicrobial peptide 2

(Aliases: leap-2)

Leap2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442553230.224
cellular ketone metabolic processGO:0042180840.203
lipid biosynthetic processGO:00086101790.180
monocarboxylic acid metabolic processGO:00327871910.165
alcohol metabolic processGO:00060661160.156
immune effector processGO:00022523210.130
cellular amine metabolic processGO:0044106440.124
amine metabolic processGO:0009308450.104
regulation of cellular amine metabolic processGO:0033238200.092
cellular amino acid metabolic processGO:00065201030.090
fatty acid metabolic processGO:00066311210.087
regulation of cellular ketone metabolic processGO:0010565660.086
regulation of cellular amino acid metabolic processGO:000652150.085
glycerolipid metabolic processGO:00464861220.081
organic hydroxy compound metabolic processGO:19016152030.080
innate immune responseGO:00450871570.080
positive regulation of cellular amine metabolic processGO:003324050.078
positive regulation of cellular amino acid metabolic processGO:004576430.068
lipid catabolic processGO:0016042690.065
cellular alcohol biosynthetic processGO:004410830.065
cellular lipid catabolic processGO:0044242520.063
oxidative demethylationGO:007098910.063
lipid homeostasisGO:0055088630.063
oxidation reduction processGO:00551143420.061
naphthalene containing compound metabolic processGO:009042010.060
regulation of secretionGO:00510462740.059
naphthalene metabolic processGO:001893110.059
calcitriol biosynthetic process from calciolGO:003637830.058
small molecule biosynthetic processGO:00442831320.058
response to organic cyclic compoundGO:00140701980.057
peptidyl amino acid modificationGO:00181933360.057
vitamin d3 metabolic processGO:007064030.053
steroid metabolic processGO:00082021190.050
cation transportGO:00068123990.050
regulation of defense responseGO:00313472330.049
regulation of ion transportGO:00432692150.047
short chain fatty acid catabolic processGO:001962620.047
apoptotic signaling pathwayGO:00971903060.046
transmembrane transportGO:00550854120.046
saturated monocarboxylic acid metabolic processGO:003278820.045
fat soluble vitamin biosynthetic processGO:004236240.045
sterol metabolic processGO:0016125580.044
peptide hormone secretionGO:00300721090.044
short chain fatty acid metabolic processGO:004645960.043
nitrogen compound transportGO:00717052710.043
isoprenoid metabolic processGO:0006720290.042
cation transmembrane transportGO:00986552660.041
fatty acid derivative metabolic processGO:1901568330.041
regulation of hydrolase activityGO:00513362460.038
carbohydrate metabolic processGO:00059752300.038
glycoprotein metabolic processGO:00091001160.038
hematopoietic progenitor cell differentiationGO:00022441430.038
cholesterol homeostasisGO:0042632440.037
positive regulation of protein phosphorylationGO:00019342420.037
regulation of secretion by cellGO:19035302490.036
cofactor metabolic processGO:0051186800.036
g protein coupled receptor signaling pathwayGO:00071862430.033
organic acid biosynthetic processGO:0016053860.033
lipid transportGO:0006869980.033
reactive nitrogen species metabolic processGO:200105700.032
regulation of multi organism processGO:00439001110.032
small molecule catabolic processGO:0044282710.032
reactive oxygen species metabolic processGO:0072593840.031
cholesterol metabolic processGO:0008203560.031
establishment of blood nerve barrierGO:000806530.030
ion transmembrane transportGO:00342203610.030
peptide transportGO:00158331330.029
hormone metabolic processGO:0042445860.029
positive regulation of protein modification processGO:00314012990.029
alcohol biosynthetic processGO:0046165430.028
icosanoid metabolic processGO:0006690330.028
vitamin d biosynthetic processGO:004236830.028
purine containing compound metabolic processGO:00725213110.028
regulation of hormone levelsGO:00108172110.028
cellular alcohol metabolic processGO:004410730.028
long chain fatty acid metabolic processGO:0001676260.028
diterpenoid metabolic processGO:0016101240.028
negative regulation of protein metabolic processGO:00512482820.027
retinoid metabolic processGO:0001523240.027
carbohydrate derivative biosynthetic processGO:19011371830.027
regulation of hormone secretionGO:0046883880.027
cellular ion homeostasisGO:00068731650.027
anion transportGO:00068201770.026
cellular response to cadmium ionGO:007127630.026
protein maturationGO:00516041760.026
sterol homeostasisGO:0055092450.026
spermatogenesisGO:00072832840.026
negative regulation of immune system processGO:00026832090.026
nucleoside phosphate metabolic processGO:00067533380.026
diterpenoid biosynthetic processGO:001610270.026
reactive oxygen species biosynthetic processGO:190340980.025
nucleobase containing small molecule metabolic processGO:00550863520.025
unsaturated fatty acid metabolic processGO:0033559310.025
response to inorganic substanceGO:0010035960.025
regulation of cytokine productionGO:00018172660.025
drug metabolic processGO:001714440.025
macromolecule catabolic processGO:00090572810.025
sulfur compound metabolic processGO:00067901000.024
regulation of homeostatic processGO:00328441820.024
ribonucleotide metabolic processGO:00092592910.024
organonitrogen compound catabolic processGO:19015652640.024
negative regulation of molecular functionGO:00440922580.024
maintenance of locationGO:0051235890.023
positive regulation of secretionGO:00510471300.023
response to acid chemicalGO:00011011110.023
glycosyl compound metabolic processGO:19016572460.023
organic cyclic compound catabolic processGO:19013612950.023
cellular response to lipidGO:00713961450.022
purine nucleotide metabolic processGO:00061633020.022
secondary alcohol metabolic processGO:190265230.022
response to drugGO:0042493750.022
response to organonitrogen compoundGO:00102432460.022
amide transportGO:00428861380.022
negative regulation of defense responseGO:0031348770.022
regulation of apoptotic signaling pathwayGO:20012331970.021
cellular response to peptideGO:1901653920.021
regulation of blood pressureGO:0008217930.021
glycoprotein biosynthetic processGO:0009101890.021
hormone secretionGO:00468791280.021
synaptic transmissionGO:00072683290.021
lipid localizationGO:00108761260.021
arachidonic acid metabolic processGO:0019369140.021
negative regulation of hydrolase activityGO:0051346710.021
response to growth factorGO:00708481980.021
nucleoside phosphate catabolic processGO:19012922220.020
aromatic compound catabolic processGO:00194392860.020
response to peptideGO:19016521360.020
sodium ion transmembrane transportGO:0035725490.020
positive regulation of transferase activityGO:00513471670.020
monocarboxylic acid biosynthetic processGO:0072330610.020
steroid biosynthetic processGO:0006694470.020
positive regulation of protein kinase activityGO:00458601440.020
terpenoid biosynthetic processGO:001611470.020
organophosphate catabolic processGO:00464342320.020
regulation of protein localizationGO:00328802310.020
positive regulation of mapk cascadeGO:00434101700.019
cell type specific apoptotic processGO:00972852680.019
proteoglycan metabolic processGO:0006029380.019
sensory perceptionGO:00076002450.019
ribose phosphate metabolic processGO:00196932910.019
cation homeostasisGO:00550802120.019
regulation of myeloid cell differentiationGO:0045637960.019
glucuronate metabolic processGO:001958520.019
purine nucleoside metabolic processGO:00422782410.019
cytoplasmic transportGO:00164822340.019
cellular chemical homeostasisGO:00550822150.019
regulation of cellular catabolic processGO:00313292420.019
nucleotide metabolic processGO:00091173320.019
cell adhesionGO:00071553290.018
regulation of organelle organizationGO:00330432890.018
regulation of proteolysisGO:00301621640.018
monosaccharide metabolic processGO:00059961060.018
camera type eye developmentGO:00430102660.018
purine containing compound catabolic processGO:00725232130.018
negative regulation of cellular protein metabolic processGO:00322692470.018
inorganic cation transmembrane transportGO:00986622070.018
multicellular organism growthGO:00352641610.018
multi multicellular organism processGO:00447061090.018
protein glycosylationGO:0006486550.018
bone developmentGO:00603481200.018
regulation of reactive oxygen species metabolic processGO:2000377400.018
organic acid transportGO:00158491010.018
fat cell differentiationGO:00454441600.018
organic hydroxy compound biosynthetic processGO:1901617770.018
cytokine productionGO:00018163190.018
glycosylationGO:0070085620.018
regulation of protein transportGO:00512231630.017
purine ribonucleoside metabolic processGO:00461282410.017
cellular response to inorganic substanceGO:0071241370.017
small gtpase mediated signal transductionGO:0007264970.017
carbohydrate derivative catabolic processGO:19011362310.017
regulation of system processGO:00440572000.017
negative regulation of cellular amine metabolic processGO:003323910.017
cellular homeostasisGO:00197252400.017
regulation of protein processingGO:0070613960.017
regulation of protein kinase activityGO:00458592320.017
regulation of protein maturationGO:1903317960.017
positive regulation of hormone secretionGO:0046887380.017
cell killingGO:0001906670.017
organonitrogen compound biosynthetic processGO:19015661920.017
response to nutrient levelsGO:00316671090.017
regulation of protein serine threonine kinase activityGO:00719001570.017
regulation of anatomical structure sizeGO:00900661780.017
succinyl coa metabolic processGO:000610410.017
cellular response to hormone stimulusGO:00328701500.017
acylglycerol metabolic processGO:0006639550.017
nuclear transportGO:00511691390.016
carboxylic acid biosynthetic processGO:0046394860.016
actin cytoskeleton organizationGO:00300362200.016
peptide secretionGO:00027901140.016
ribonucleoside triphosphate metabolic processGO:00091992200.016
male gamete generationGO:00482322850.016
terpenoid metabolic processGO:0006721250.016
posttranscriptional regulation of gene expressionGO:00106081550.016
tissue remodelingGO:00487711020.016
ossificationGO:00015032160.016
regulation of protein secretionGO:0050708820.016
nucleocytoplasmic transportGO:00069131390.016
protein processingGO:00164851630.016
leukocyte mediated immunityGO:00024431740.016
cellular response to organonitrogen compoundGO:00714171450.016
rho protein signal transductionGO:0007266320.016
regulation of mapk cascadeGO:00434082480.016
regulation of establishment of protein localizationGO:00702011810.016
protein localization to nucleusGO:00345041210.016
purine ribonucleotide metabolic processGO:00091502900.015
inorganic ion transmembrane transportGO:00986602340.015
activation of immune responseGO:00022531380.015
regulation of endopeptidase activityGO:0052548890.015
regulation of feeding behaviorGO:006025930.015
regulation of peptide transportGO:0090087910.015
nucleoside triphosphate metabolic processGO:00091412300.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
membrane organizationGO:00610242450.015
regulation of cytoskeleton organizationGO:00514931220.015
mapk cascadeGO:00001652810.015
lymphocyte mediated immunityGO:00024491390.015
regulation of reactive oxygen species biosynthetic processGO:190342620.015
purine ribonucleotide catabolic processGO:00091542080.015
glycerophospholipid metabolic processGO:0006650710.015
regulation of cellular component biogenesisGO:00440871810.015
renal system processGO:0003014480.015
negative regulation of cell proliferationGO:00082852960.014
regulation of interleukin 8 productionGO:003267730.014
sodium ion transportGO:0006814730.014
sensory organ morphogenesisGO:00905962420.014
fatty acid catabolic processGO:0009062250.014
negative regulation of cellular amino acid metabolic processGO:004576300.014
neutral lipid metabolic processGO:0006638570.014
nucleoside metabolic processGO:00091162460.014
forebrain developmentGO:00309003020.014
regulation of transferase activityGO:00513382630.014
purine nucleoside triphosphate catabolic processGO:00091462030.014
testosterone biosynthetic processGO:006137020.014
mesodermal cell migrationGO:000807840.014
coenzyme metabolic processGO:0006732520.014
cellular response to cytokine stimulusGO:00713451890.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.014
myeloid cell differentiationGO:00300992330.014
cellular amide metabolic processGO:0043603580.014
ribonucleotide catabolic processGO:00092612080.013
positive regulation of cytokine productionGO:00018191740.013
regulation of actin filament based processGO:0032970990.013
protein catabolic processGO:00301632210.013
peptidyl serine modificationGO:0018209830.013
regulation of purine nucleotide metabolic processGO:19005421690.013
regulation of cell activationGO:00508652890.013
interspecies interaction between organismsGO:0044419830.013
organic acid catabolic processGO:0016054510.013
negative regulation of protein processingGO:0010955790.013
response to metal ionGO:0010038470.013
positive regulation of programmed cell deathGO:00430682180.013
embryonic placenta developmentGO:0001892980.013
regulation of peptide secretionGO:0002791770.013
metal ion homeostasisGO:00550651890.013
heterocycle catabolic processGO:00467002800.013
negative regulation of intracellular signal transductionGO:19025321670.013
vitamin metabolic processGO:0006766230.013
negative regulation of proteolysisGO:0045861740.013
organelle fissionGO:00482851700.013
purine ribonucleoside triphosphate metabolic processGO:00092052200.013
regulation of t cell activationGO:00508631700.013
purine ribonucleoside monophosphate metabolic processGO:0009167800.013
negative regulation of growthGO:0045926990.013
response to extracellular stimulusGO:00099911270.013
response to lipopolysaccharideGO:00324961280.013
thermosensory behaviorGO:004004010.012
acylglycerol homeostasisGO:0055090160.012
purine nucleoside triphosphate metabolic processGO:00091442260.012
organophosphate biosynthetic processGO:00904071220.012
negative regulation of phosphate metabolic processGO:00459361840.012
calcium ion homeostasisGO:00550741270.012
nucleoside catabolic processGO:00091642060.012
negative regulation of cellular component organizationGO:00511291940.012
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
regulation of testosterone biosynthetic processGO:200022420.012
multicellular organismal homeostasisGO:00488711640.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
acyl coa metabolic processGO:0006637190.012
cellular response to lipopolysaccharideGO:0071222770.012
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044330.012
regulation of lymphocyte activationGO:00512492400.012
positive regulation of viral genome replicationGO:004507020.012
nucleoside triphosphate catabolic processGO:00091432050.012
blood vessel morphogenesisGO:00485142850.012
telencephalon developmentGO:00215371860.012
isoprenoid biosynthetic processGO:000829990.012
epithelial cell developmentGO:00020641590.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.012
cholesterol transportGO:0030301380.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
cellular response to growth factor stimulusGO:00713631970.012
t cell activationGO:00421102890.012
negative regulation of multi organism processGO:0043901680.012
negative regulation of protein phosphorylationGO:00019331260.012
lipoprotein metabolic processGO:0042157430.012
peptidyl tyrosine modificationGO:00182121450.012
positive regulation of secretion by cellGO:19035321140.012
purine nucleotide catabolic processGO:00061952110.012
positive regulation of immune effector processGO:00026991070.012
actin filament organizationGO:00070151130.012
phospholipid metabolic processGO:0006644870.012
response to insulinGO:00328681000.012
cellular metal ion homeostasisGO:00068751510.012
organic hydroxy compound transportGO:0015850930.011
regulation of defense response to bacteriumGO:190042430.011
ribonucleoside catabolic processGO:00424542060.011
cellular response to biotic stimulusGO:0071216920.011
regulation of actin cytoskeleton organizationGO:0032956840.011
regulation of cell adhesionGO:00301551540.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
muscle cell differentiationGO:00426922610.011
anatomical structure homeostasisGO:00602491450.011
regulation of cell migrationGO:00303342190.011
intracellular protein transportGO:00068862040.011
very long chain fatty acid metabolic processGO:000003880.011
cellular protein complex assemblyGO:00436231160.011
uronic acid metabolic processGO:000606320.011
regulation of inflammatory responseGO:00507271470.011
dephosphorylationGO:00163111290.011
regulation of cellular carbohydrate metabolic processGO:0010675750.011
cellular nitrogen compound catabolic processGO:00442702800.011
purine containing compound biosynthetic processGO:0072522700.011
regulation of lipid transportGO:0032368360.011
protein localization to membraneGO:00726571080.011
regulation of systemic arterial blood pressureGO:0003073610.011
glucose homeostasisGO:00425931280.011
regulation of lymphocyte mediated immunityGO:0002706840.011
peptidyl tyrosine phosphorylationGO:00181081430.011
regulation of vesicle mediated transportGO:00606271390.011
regulation of kinase activityGO:00435492490.011
ribonucleoside metabolic processGO:00091192450.011
purine nucleoside catabolic processGO:00061522050.011
negative regulation of protein modification processGO:00314001630.011
response to phenylpropanoidGO:0080184220.011
cell growthGO:00160491300.011
regulation of intracellular transportGO:00323861590.011
positive regulation of ion transportGO:0043270650.011
striated muscle myosin thick filament assemblyGO:007168810.011
regulation of ketone biosynthetic processGO:001056620.011
protein importGO:00170381010.011
progesterone metabolic processGO:004244840.011
phosphatidylinositol mediated signalingGO:0048015410.011
nucleotide catabolic processGO:00091662170.011
cognitionGO:00508901490.011
regulation of peptidyl tyrosine phosphorylationGO:0050730930.011
protein targetingGO:00066051430.011
mrna metabolic processGO:0016071840.011
negative regulation of protein maturationGO:1903318790.011
neuron deathGO:00709971540.011
female meiosis chromosome segregationGO:001632110.011
regulation of cysteine type endopeptidase activityGO:2000116650.011
rna processingGO:00063961050.011
carbohydrate transportGO:0008643620.011
generation of precursor metabolites and energyGO:00060911030.011
rhythmic processGO:00485111740.010
pallium developmentGO:00215431200.010
positive regulation of reactive oxygen species metabolic processGO:2000379110.010
regulation of cell growthGO:0001558910.010
ras protein signal transductionGO:0007265770.010
digestive tract morphogenesisGO:00485461470.010
regulation of lipid metabolic processGO:00192161180.010
retinoic acid biosynthetic processGO:000213870.010
innate immune response in mucosaGO:000222730.010
extracellular structure organizationGO:00430621480.010
liver developmentGO:0001889660.010
cytosolic calcium ion homeostasisGO:0051480700.010
negative regulation of peptidase activityGO:0010466460.010
cellular response to molecule of bacterial originGO:0071219830.010
retinoic acid metabolic processGO:0042573120.010
purine ribonucleoside catabolic processGO:00461302050.010
blood circulationGO:00080151950.010
homeostasis of number of cellsGO:00488722100.010
regulation of neurotransmitter levelsGO:0001505870.010
nucleoside phosphate biosynthetic processGO:1901293790.010
insulin secretionGO:0030073890.010
cellular response to insulin stimulusGO:0032869780.010
single organism cell adhesionGO:00986021560.010
response to radiationGO:00093141650.010
drug catabolic processGO:004273720.010
cellular response to peptide hormone stimulusGO:0071375920.010
glucose metabolic processGO:0006006920.010

Leap2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.062
inherited metabolic disorderDOID:65500.026
nervous system diseaseDOID:86300.015
disease of anatomical entityDOID:700.015