Mus musculus

104 known processes

Msh6

mutS homolog 6 (E. coli)

(Aliases: AW550279,GTBP,Gtmbp,AU044881)

Msh6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.451
mitotic cell cycle processGO:19030471590.279
intrinsic apoptotic signaling pathwayGO:00971931320.249
cellular response to dna damage stimulusGO:00069742070.227
regulation of cell cycleGO:00517262810.181
apoptotic signaling pathwayGO:00971903060.179
nucleic acid phosphodiester bond hydrolysisGO:0090305490.154
mitotic cell cycleGO:00002781950.135
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.132
glycosyl compound metabolic processGO:19016572460.130
Human Yeast
mrna splicing via spliceosomeGO:0000398430.114
regulation of cell cycle phase transitionGO:1901987770.110
meiotic nuclear divisionGO:00071261150.107
Yeast
dna recombinationGO:0006310920.103
response to radiationGO:00093141650.101
dna repairGO:00062811070.100
rna processingGO:00063961050.098
germ cell developmentGO:00072811850.091
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046610.090
aromatic compound catabolic processGO:00194392860.089
Human Yeast
organelle fissionGO:00482851700.084
Yeast
rna phosphodiester bond hydrolysis exonucleolyticGO:009050340.081
myeloid cell differentiationGO:00300992330.077
purine ribonucleoside catabolic processGO:00461302050.076
Human Yeast
atp catabolic processGO:0006200550.076
Human Yeast
rhythmic processGO:00485111740.074
nucleoside phosphate catabolic processGO:19012922220.071
Human Yeast
nucleoside catabolic processGO:00091642060.071
Human Yeast
spermatogenesisGO:00072832840.068
purine nucleoside metabolic processGO:00422782410.068
Human Yeast
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.067
regulation of response to woundingGO:19030341890.066
ribonucleotide catabolic processGO:00092612080.063
Human Yeast
nucleotide metabolic processGO:00091173320.063
Human Yeast
purine nucleotide metabolic processGO:00061633020.062
Human Yeast
nucleoside monophosphate metabolic processGO:0009123850.060
Human Yeast
nucleotide catabolic processGO:00091662170.059
Human Yeast
mrna metabolic processGO:0016071840.059
purine nucleoside triphosphate catabolic processGO:00091462030.058
Human Yeast
purine nucleoside monophosphate catabolic processGO:0009128580.058
Human Yeast
cell fate commitmentGO:00451652100.057
nucleoside metabolic processGO:00091162460.056
Human Yeast
regulation of cell cycle processGO:00105641600.055
chromosome segregationGO:0007059480.055
covalent chromatin modificationGO:00165691630.053
muscle cell differentiationGO:00426922610.052
double strand break repairGO:0006302480.052
histone modificationGO:00165701590.052
macromolecule catabolic processGO:00090572810.052
snrna metabolic processGO:001607310.051
regulation of mitotic cell cycle phase transitionGO:1901990730.050
positive regulation of apoptotic processGO:00430652170.049
negative regulation of protein modification processGO:00314001630.047
ribonucleotide metabolic processGO:00092592910.047
Human Yeast
regulation of apoptotic signaling pathwayGO:20012331970.046
response to organonitrogen compoundGO:00102432460.046
methylationGO:00322591340.046
meiotic cell cycleGO:00513211220.045
Yeast
cell cycle g1 s phase transitionGO:0044843570.043
regulation of intracellular transportGO:00323861590.043
morphogenesis of a branching epitheliumGO:00611381930.042
lateral inhibitionGO:004633110.042
microtubule based processGO:00070172360.042
male gamete generationGO:00482322850.040
intracellular mrna localizationGO:000829840.040
cell divisionGO:00513011200.040
circadian rhythmGO:00076231140.040
nucleobase containing small molecule metabolic processGO:00550863520.040
Human Yeast
chromatin modificationGO:00165681870.040
g1 s transition of mitotic cell cycleGO:0000082570.039
cellular macromolecule catabolic processGO:00442652060.038
purine ribonucleoside metabolic processGO:00461282410.037
Human Yeast
response to ionizing radiationGO:0010212420.037
heterocycle catabolic processGO:00467002800.037
Human Yeast
negative regulation of mitotic cell cycle phase transitionGO:1901991450.037
cellular amino acid metabolic processGO:00065201030.037
maintenance of locationGO:0051235890.037
cell type specific apoptotic processGO:00972852680.036
ribonucleoside metabolic processGO:00091192450.036
Human Yeast
purine nucleotide catabolic processGO:00061952110.036
Human Yeast
oxidation reduction processGO:00551143420.036
negative regulation of cellular protein metabolic processGO:00322692470.035
ribonucleoside triphosphate catabolic processGO:00092031990.035
Human Yeast
endocytosisGO:00068971680.035
rna splicing via transesterification reactionsGO:0000375430.035
ribonucleoprotein complex subunit organizationGO:0071826280.035
ncrna 3 end processingGO:004362820.034
microtubule cytoskeleton organizationGO:00002261570.034
purine ribonucleoside monophosphate metabolic processGO:0009167800.033
Human Yeast
response to light stimulusGO:00094161350.033
cellular response to organonitrogen compoundGO:00714171450.033
negative regulation of molecular functionGO:00440922580.032
response to peptideGO:19016521360.032
myeloid leukocyte differentiationGO:00025731190.032
angiogenesisGO:00015252010.032
rna splicingGO:0008380540.031
purine nucleoside catabolic processGO:00061522050.031
Human Yeast
positive regulation of cell deathGO:00109422240.031
positive regulation of apoptotic signaling pathwayGO:2001235950.030
purine ribonucleotide metabolic processGO:00091502900.030
Human Yeast
epithelial tube morphogenesisGO:00605623030.030
purine containing compound metabolic processGO:00725213110.030
Human Yeast
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.029
nucleoside monophosphate catabolic processGO:0009125590.029
Human Yeast
positive regulation of programmed cell deathGO:00430682180.029
regulation of circadian rhythmGO:0042752580.028
purine containing compound catabolic processGO:00725232130.027
Human Yeast
female gamete generationGO:0007292740.027
purine nucleoside triphosphate metabolic processGO:00091442260.027
Human Yeast
cell cycle checkpointGO:0000075470.027
sister chromatid segregationGO:0000819200.027
leukocyte differentiationGO:00025213420.027
membrane organizationGO:00610242450.027
blood vessel morphogenesisGO:00485142850.027
amine metabolic processGO:0009308450.026
peptidyl lysine modificationGO:0018205770.026
purine ribonucleotide catabolic processGO:00091542080.026
Human Yeast
response to organic cyclic compoundGO:00140701980.025
organism emergence from protective structureGO:007168440.025
regulation of organelle organizationGO:00330432890.025
protein catabolic processGO:00301632210.025
purine nucleoside monophosphate metabolic processGO:0009126810.025
Human Yeast
immunoglobulin productionGO:0002377730.025
regulation of establishment of protein localizationGO:00702011810.025
posttranscriptional regulation of gene expressionGO:00106081550.025
purine ribonucleoside triphosphate metabolic processGO:00092052200.025
Human Yeast
chromatin organizationGO:00063252060.024
mitotic nuclear divisionGO:0007067480.024
cellular response to radiationGO:0071478280.024
regulation of myeloid cell differentiationGO:0045637960.024
production of molecular mediator of immune responseGO:00024401030.024
regulation of g1 s transition of mitotic cell cycleGO:2000045350.024
ribonucleoside triphosphate metabolic processGO:00091992200.023
Human Yeast
snrna processingGO:001618010.023
cellular ketone metabolic processGO:0042180840.023
ribose phosphate metabolic processGO:00196932910.023
Human Yeast
organonitrogen compound catabolic processGO:19015652640.023
Human Yeast
morphogenesis of embryonic epitheliumGO:00163311590.023
cleavage involved in rrna processingGO:000046910.022
cellular protein catabolic processGO:00442571550.022
carbohydrate derivative catabolic processGO:19011362310.022
Human Yeast
glycosyl compound catabolic processGO:19016582060.022
Human Yeast
modification dependent macromolecule catabolic processGO:00436321330.022
positive regulation of immune effector processGO:00026991070.022
protein modification by small protein conjugation or removalGO:00706472070.022
nuclear divisionGO:00002801580.022
Yeast
purine ribonucleoside triphosphate catabolic processGO:00092071990.021
Human Yeast
regulation of mitotic cell cycleGO:00073461260.021
camera type eye developmentGO:00430102660.021
organelle assemblyGO:00709251770.021
nucleoside phosphate metabolic processGO:00067533380.021
Human Yeast
regulation of protein transportGO:00512231630.021
dna replicationGO:0006260520.021
ossificationGO:00015032160.021
b cell activationGO:00421131610.020
regulation of cellular amino acid metabolic processGO:000652150.020
nucleoside triphosphate catabolic processGO:00091432050.020
Human Yeast
negative regulation of protein metabolic processGO:00512482820.020
cellular amine metabolic processGO:0044106440.020
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.020
organophosphate catabolic processGO:00464342320.020
Human Yeast
regulation of inflammatory responseGO:00507271470.020
negative regulation of histone h3 k9 methylationGO:005157340.019
macromolecule methylationGO:00434141200.019
negative regulation of cell proliferationGO:00082852960.019
locomotory behaviorGO:00076261950.019
developmental maturationGO:00217001930.019
antimicrobial peptide productionGO:000277520.019
regulation of proteolysisGO:00301621640.019
regulation of response to dna damage stimulusGO:2001020340.019
organic cyclic compound catabolic processGO:19013612950.019
Human Yeast
somatic diversification of immunoglobulinsGO:0016445430.019
embryonic epithelial tube formationGO:00018381300.019
histone methylationGO:0016571710.019
regulation of chromosome organizationGO:0033044830.018
compound eye developmentGO:004874910.018
modification dependent protein catabolic processGO:00199411330.018
ubiquitin dependent protein catabolic processGO:00065111290.018
maturation of 5 8s rrnaGO:000046010.018
regulation of hormone levelsGO:00108172110.018
regulation of cell cycle g1 s phase transitionGO:1902806350.018
rna 3 end processingGO:0031123200.018
nucleocytoplasmic transportGO:00069131390.018
centromere complex assemblyGO:003450830.018
cell maturationGO:00484691270.018
anatomical structure homeostasisGO:00602491450.017
protein localization to chromosome centromeric regionGO:007145910.017
positive regulation of protein modification processGO:00314012990.017
circadian regulation of gene expressionGO:0032922480.017
ribonucleoside catabolic processGO:00424542060.017
Human Yeast
regulation of cellular component biogenesisGO:00440871810.017
regulation of mrna stabilityGO:0043488230.017
negative regulation of cell cycle phase transitionGO:1901988480.017
development of primary sexual characteristicsGO:00451371430.017
response to inorganic substanceGO:0010035960.017
regulation of defense responseGO:00313472330.017
response to oxidative stressGO:00069791230.016
skin developmentGO:00435882200.016
protein localization to organelleGO:00333651850.016
nucleus organizationGO:0006997450.016
connective tissue developmentGO:00614481790.016
regulation of cytoplasmic transportGO:19036491120.016
positive regulation of cellular amino acid metabolic processGO:004576430.016
nucleoside triphosphate metabolic processGO:00091412300.016
Human Yeast
positive regulation of neuron differentiationGO:00456661410.016
positive regulation of proteolysisGO:0045862850.016
somatic cell dna recombinationGO:0016444510.016
ribonucleoside monophosphate catabolic processGO:0009158570.016
Human Yeast
regulation of cellular response to stressGO:00801351590.016
somatic stem cell maintenanceGO:0035019470.016
positive regulation of organelle organizationGO:00106381280.016
myeloid cell homeostasisGO:00022621140.015
cytoplasmic transportGO:00164822340.015
organonitrogen compound biosynthetic processGO:19015661920.015
digestive tract developmentGO:00485651900.015
regulation of cellular ketone metabolic processGO:0010565660.015
regulation of neuron deathGO:19012141340.015
oogenesisGO:0048477560.015
response to peptide hormoneGO:00434341270.015
positive regulation of cell cycleGO:0045787920.015
neuron apoptotic processGO:00514021420.015
cellular protein complex assemblyGO:00436231160.014
lymphocyte mediated immunityGO:00024491390.014
protein acylationGO:0043543640.014
protein modification by small protein conjugationGO:00324461870.014
blastocyst developmentGO:0001824800.014
stem cell developmentGO:00488642190.014
negative regulation of synapse assemblyGO:005196430.014
regulation of intracellular protein transportGO:0033157820.014
oocyte anterior posterior axis specificationGO:000731420.014
mitotic sister chromatid segregationGO:0000070140.014
intracellular receptor signaling pathwayGO:0030522740.014
cell adhesionGO:00071553290.014
response to lipopolysaccharideGO:00324961280.014
hematopoietic progenitor cell differentiationGO:00022441430.014
lipid localizationGO:00108761260.014
cellular nitrogen compound catabolic processGO:00442702800.014
Human Yeast
negative regulation of cellular component organizationGO:00511291940.014
regulation of nucleocytoplasmic transportGO:0046822730.014
sister chromatid cohesionGO:0007062120.013
morphogenesis of a branching structureGO:00017632030.013
regulation of chromatin silencingGO:003193520.013
cellular response to abiotic stimulusGO:0071214560.013
dna damage response signal transduction by p53 class mediatorGO:0030330190.013
establishment of organelle localizationGO:00516561220.013
cell growthGO:00160491300.013
cellular response to transforming growth factor beta stimulusGO:0071560880.013
inflammatory responseGO:00069542440.013
regulation of cell activationGO:00508652890.013
ribonucleoside monophosphate metabolic processGO:0009161800.013
Human Yeast
erythrocyte differentiationGO:0030218880.013
regulation of synaptic growth at neuromuscular junctionGO:000858240.013
translationGO:0006412930.013
establishment of protein localization to organelleGO:00725941180.013
engulfment of apoptotic cellGO:004365230.012
regulation of system processGO:00440572000.012
epidermis developmentGO:00085441870.012
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.012
epithelial tube formationGO:00721751300.012
snrna 3 end processingGO:003447210.012
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.012
neuroblast differentiationGO:001401620.012
rna phosphodiester bond hydrolysisGO:0090501190.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
fat cell differentiationGO:00454441600.012
positive regulation of chromosome organizationGO:2001252330.012
lipid biosynthetic processGO:00086101790.012
spermatid developmentGO:00072861080.012
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.012
rhythmic behaviorGO:0007622150.012
gene silencing by rnaGO:0031047190.012
t cell activationGO:00421102890.012
negative regulation of mitotic cell cycleGO:0045930580.012
protein ubiquitinationGO:00165671710.012
glial cell differentiationGO:00100011310.012
protein dna complex subunit organizationGO:0071824280.012
maternal determination of anterior posterior axis embryoGO:000835820.012
branching morphogenesis of an epithelial tubeGO:00487541590.012
internal peptidyl lysine acetylationGO:0018393420.012
male meiosis iGO:0007141160.012
lymphocyte differentiationGO:00300982420.012
positive regulation of nervous system developmentGO:00519622210.012
mrna processingGO:0006397630.012
peptidyl amino acid modificationGO:00181933360.012
protein maturationGO:00516041760.012
dna conformation changeGO:0071103370.011
rna interferenceGO:001624620.011
dna integrity checkpointGO:0031570280.011
positive regulation of cellular component biogenesisGO:0044089940.011
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.011
nuclear transportGO:00511691390.011
histone lysine methylationGO:0034968500.011
multicellular organismal signalingGO:0035637910.011
ncrna processingGO:0034470260.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
internal protein amino acid acetylationGO:0006475420.011
endomembrane system organizationGO:00102561470.011
synaptic transmissionGO:00072683290.011
axonogenesisGO:00074092740.011
regulation of interleukin 1 alpha productionGO:003265040.011
positive regulation of mitotic cell cycle phase transitionGO:1901992170.011
ventricular septum morphogenesisGO:0060412270.011
cellular response to organic cyclic compoundGO:0071407870.011
pole plasm assemblyGO:000731520.011
glucose homeostasisGO:00425931280.011
antimicrobial peptide biosynthetic processGO:000277720.011
cellular response to light stimulusGO:0071482190.011
positive regulation of production of molecular mediator of immune responseGO:0002702450.011
positive regulation of cytokine productionGO:00018191740.011
hindbrain developmentGO:00309021280.011
cellular response to hormone stimulusGO:00328701500.011
regulation of nuclear divisionGO:0051783560.011
regulation of neuron projection developmentGO:00109751690.011
intracellular protein transportGO:00068862040.011
dna damage checkpointGO:0000077260.011
homeostasis of number of cellsGO:00488722100.011
positive regulation of adaptive immune responseGO:0002821610.011
tube formationGO:00351481400.011
cellular chemical homeostasisGO:00550822150.011
positive regulation of intracellular protein transportGO:0090316420.011
regulation of cell morphogenesis involved in differentiationGO:00107691510.010
carbohydrate homeostasisGO:00335001280.010
leukocyte mediated immunityGO:00024431740.010
regulation of transferase activityGO:00513382630.010
proteasomal protein catabolic processGO:0010498980.010
mrna destabilizationGO:006115740.010
tissue homeostasisGO:00018941150.010
positive regulation of protein phosphorylationGO:00019342420.010
negative regulation of cell cycleGO:00457861230.010
negative regulation of apoptotic signaling pathwayGO:20012341040.010
nuclear dna replicationGO:003326030.010
response to transforming growth factor betaGO:0071559880.010

Msh6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.063
Human
disease of cellular proliferationDOID:1456600.063
Human
organ system cancerDOID:005068600.055
Human
nervous system diseaseDOID:86300.042
disease of anatomical entityDOID:700.042
central nervous system diseaseDOID:33100.028
neurodegenerative diseaseDOID:128900.013
thoracic cancerDOID:509300.012
breast cancerDOID:161200.011
motor neuron diseaseDOID:23100.010
amyotrophic lateral sclerosisDOID:33200.010