Mus musculus

54 known processes

Mapkapk5

MAP kinase-activated protein kinase 5

(Aliases: MK5,PRAK)

Mapkapk5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular nitrogen compound catabolic processGO:00442702800.110
amine metabolic processGO:0009308450.096
cellular amino acid metabolic processGO:00065201030.088
organonitrogen compound catabolic processGO:19015652640.087
cellular amine metabolic processGO:0044106440.080
regulation of cellular amine metabolic processGO:0033238200.077
regulation of cellular ketone metabolic processGO:0010565660.076
heterocycle catabolic processGO:00467002800.067
cellular ketone metabolic processGO:0042180840.063
apoptotic signaling pathwayGO:00971903060.062
actin cytoskeleton organizationGO:00300362200.060
positive regulation of cellular amino acid metabolic processGO:004576430.060
regulation of cellular amino acid metabolic processGO:000652150.059
negative regulation of protein metabolic processGO:00512482820.059
purine ribonucleoside metabolic processGO:00461282410.059
positive regulation of cellular amine metabolic processGO:003324050.058
organic cyclic compound catabolic processGO:19013612950.058
purine ribonucleotide metabolic processGO:00091502900.058
nucleobase containing small molecule metabolic processGO:00550863520.051
nucleotide metabolic processGO:00091173320.050
ribonucleotide catabolic processGO:00092612080.048
peptidyl amino acid modificationGO:00181933360.048
glycosyl compound catabolic processGO:19016582060.046
positive regulation of cell deathGO:00109422240.044
spermatogenesisGO:00072832840.044
ras protein signal transductionGO:0007265770.044
regulation of apoptotic signaling pathwayGO:20012331970.043
carbohydrate derivative catabolic processGO:19011362310.043
purine containing compound catabolic processGO:00725232130.042
positive regulation of apoptotic processGO:00430652170.042
male gamete generationGO:00482322850.042
nucleoside catabolic processGO:00091642060.041
negative regulation of phosphate metabolic processGO:00459361840.041
purine nucleoside metabolic processGO:00422782410.041
purine nucleotide catabolic processGO:00061952110.041
aromatic compound catabolic processGO:00194392860.040
mitochondrion organizationGO:00070051340.039
nitrogen compound transportGO:00717052710.038
negative regulation of phosphorus metabolic processGO:00105631840.038
cell type specific apoptotic processGO:00972852680.038
purine nucleotide metabolic processGO:00061633020.038
membrane organizationGO:00610242450.038
nucleoside phosphate catabolic processGO:19012922220.037
purine nucleoside catabolic processGO:00061522050.037
cytoplasmic transportGO:00164822340.037
positive regulation of programmed cell deathGO:00430682180.036
organophosphate catabolic processGO:00464342320.036
purine ribonucleotide catabolic processGO:00091542080.035
cation transportGO:00068123990.035
ribonucleoside metabolic processGO:00091192450.035
purine containing compound metabolic processGO:00725213110.034
response to light stimulusGO:00094161350.034
glycosyl compound metabolic processGO:19016572460.034
ribonucleotide metabolic processGO:00092592910.034
response to organonitrogen compoundGO:00102432460.034
purine nucleoside triphosphate metabolic processGO:00091442260.034
negative regulation of intracellular signal transductionGO:19025321670.033
nucleotide catabolic processGO:00091662170.033
nucleoside phosphate metabolic processGO:00067533380.033
negative regulation of molecular functionGO:00440922580.033
cytokine productionGO:00018163190.033
Mouse
purine ribonucleoside catabolic processGO:00461302050.033
muscle cell differentiationGO:00426922610.032
small gtpase mediated signal transductionGO:0007264970.032
ribonucleoside triphosphate catabolic processGO:00092031990.032
dna metabolic processGO:00062593030.032
negative regulation of cellular amine metabolic processGO:003323910.031
intrinsic apoptotic signaling pathwayGO:00971931320.031
neuron deathGO:00709971540.030
regulation of cellular component biogenesisGO:00440871810.030
nucleoside triphosphate catabolic processGO:00091432050.030
protein modification by small protein conjugation or removalGO:00706472070.030
purine nucleoside triphosphate catabolic processGO:00091462030.029
positive regulation of protein phosphorylationGO:00019342420.029
protein localization to organelleGO:00333651850.029
ribose phosphate metabolic processGO:00196932910.029
wnt signaling pathwayGO:00160551880.028
organelle fissionGO:00482851700.028
negative regulation of cellular protein metabolic processGO:00322692470.027
positive regulation of protein modification processGO:00314012990.027
regulation of kinase activityGO:00435492490.027
nuclear transportGO:00511691390.027
ribonucleoside triphosphate metabolic processGO:00091992200.027
proteolysis involved in cellular protein catabolic processGO:00516031470.027
ribonucleoside monophosphate catabolic processGO:0009158570.027
cellular response to dna damage stimulusGO:00069742070.027
spermatid differentiationGO:00485151150.026
mitochondrial membrane organizationGO:0007006260.026
nucleoside monophosphate catabolic processGO:0009125590.026
nucleoside metabolic processGO:00091162460.026
regulation of cellular catabolic processGO:00313292420.026
lymphocyte differentiationGO:00300982420.026
regulation of protein kinase activityGO:00458592320.025
macromolecule catabolic processGO:00090572810.025
protein catabolic processGO:00301632210.025
neuron apoptotic processGO:00514021420.025
endomembrane system organizationGO:00102561470.025
negative regulation of cell proliferationGO:00082852960.025
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.025
protein modification by small protein conjugationGO:00324461870.024
regulation of mapk cascadeGO:00434082480.024
nucleocytoplasmic transportGO:00069131390.024
chromatin modificationGO:00165681870.024
regulation of transferase activityGO:00513382630.024
purine ribonucleoside triphosphate metabolic processGO:00092052200.024
regulation of hydrolase activityGO:00513362460.024
ribonucleoside catabolic processGO:00424542060.024
cell adhesionGO:00071553290.024
muscle tissue developmentGO:00605373080.024
t cell activationGO:00421102890.024
regulation of cytokine productionGO:00018172660.024
Mouse
response to radiationGO:00093141650.024
regulation of organelle organizationGO:00330432890.023
organelle assemblyGO:00709251770.023
mitotic cell cycle processGO:19030471590.023
regulation of mitotic cell cycleGO:00073461260.023
mitotic cell cycleGO:00002781950.023
t cell differentiationGO:00302171740.023
negative regulation of phosphorylationGO:00423261660.023
positive regulation of kinase activityGO:00336741550.023
regulation of cell cycleGO:00517262810.023
spermatid developmentGO:00072861080.022
multicellular organismal signalingGO:0035637910.022
mitochondrion degradationGO:000042230.022
nucleoside monophosphate metabolic processGO:0009123850.022
regulation of membrane potentialGO:00423911920.022
mapk cascadeGO:00001652810.021
transmembrane transportGO:00550854120.021
positive regulation of cell developmentGO:00107202370.021
modification dependent protein catabolic processGO:00199411330.021
leukocyte differentiationGO:00025213420.021
striated muscle tissue developmentGO:00147062930.021
intracellular protein transportGO:00068862040.021
negative regulation of protein modification processGO:00314001630.021
germ cell developmentGO:00072811850.021
response to oxidative stressGO:00069791230.020
purine ribonucleoside triphosphate catabolic processGO:00092071990.020
covalent chromatin modificationGO:00165691630.020
regulation of neuron apoptotic processGO:00435231220.020
cellular macromolecule catabolic processGO:00442652060.020
nucleoside triphosphate metabolic processGO:00091412300.020
cellular response to growth factor stimulusGO:00713631970.019
purine nucleoside monophosphate catabolic processGO:0009128580.019
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.019
regulation of protein serine threonine kinase activityGO:00719001570.019
cellular protein catabolic processGO:00442571550.019
multicellular organism growthGO:00352641610.019
regulation of neuron deathGO:19012141340.019
camera type eye developmentGO:00430102660.019
g protein coupled receptor signaling pathwayGO:00071862430.019
cellular lipid metabolic processGO:00442553230.019
actomyosin structure organizationGO:0031032560.019
muscle cell developmentGO:00550011330.019
lipid biosynthetic processGO:00086101790.018
synaptic transmissionGO:00072683290.018
regulation of cell activationGO:00508652890.018
regulation of protein localizationGO:00328802310.018
regulation of ras protein signal transductionGO:00465781140.018
phosphatidylethanolamine metabolic processGO:004633720.018
negative regulation of cellular component organizationGO:00511291940.018
regulation of cell projection organizationGO:00313442060.018
regulation of cell cycle processGO:00105641600.018
negative regulation of protein phosphorylationGO:00019331260.018
positive regulation of protein kinase activityGO:00458601440.018
mrna metabolic processGO:0016071840.018
reactive oxygen species metabolic processGO:0072593840.018
regulation of secretionGO:00510462740.018
rhythmic processGO:00485111740.018
cellular component assembly involved in morphogenesisGO:00109271390.017
cellular protein complex assemblyGO:00436231160.017
response to organic cyclic compoundGO:00140701980.017
organonitrogen compound biosynthetic processGO:19015661920.017
regulation of purine nucleotide metabolic processGO:19005421690.017
striated muscle cell developmentGO:00550021250.017
protein localization to membraneGO:00726571080.017
regulation of striated muscle cell differentiationGO:0051153810.017
negative regulation of growthGO:0045926990.017
negative regulation of apoptotic signaling pathwayGO:20012341040.017
purine ribonucleoside monophosphate catabolic processGO:0009169570.017
regulation of neuron differentiationGO:00456642810.017
cellular homeostasisGO:00197252400.017
positive regulation of transferase activityGO:00513471670.017
positive regulation of nervous system developmentGO:00519622210.017
negative regulation of cellular amino acid metabolic processGO:004576300.017
regulation of ion transportGO:00432692150.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
protein processingGO:00164851630.016
microtubule based processGO:00070172360.016
canonical wnt signaling pathwayGO:00600701300.016
ribonucleoside monophosphate metabolic processGO:0009161800.016
immune effector processGO:00022523210.016
neuronal action potentialGO:0019228540.016
maintenance of locationGO:0051235890.016
regulation of secretion by cellGO:19035302490.016
response to oxygen levelsGO:0070482620.016
ion transmembrane transportGO:00342203610.016
ubiquitin dependent protein catabolic processGO:00065111290.016
regulation of multi organism processGO:00439001110.016
response to extracellular stimulusGO:00099911270.016
blastocyst developmentGO:0001824800.016
regulation of lymphocyte activationGO:00512492400.016
homeostasis of number of cellsGO:00488722100.016
positive regulation of nucleotide metabolic processGO:00459811140.016
positive regulation of mapk cascadeGO:00434101700.016
response to lipopolysaccharideGO:00324961280.016
Mouse
regulation of phosphatidylcholine biosynthetic processGO:200124520.016
gland developmentGO:00487323300.016
divalent inorganic cation transportGO:00725111780.015
transmission of nerve impulseGO:0019226760.015
chromatin organizationGO:00063252060.015
regulation of protein catabolic processGO:00421761080.015
myosin filament organizationGO:003103330.015
cellular chemical homeostasisGO:00550822150.015
gonad developmentGO:00084061410.015
regulation of neuron projection developmentGO:00109751690.015
forebrain developmentGO:00309003020.015
digestive system developmentGO:00551232000.015
regulation of map kinase activityGO:00434051200.015
histone modificationGO:00165701590.015
regulation of t cell activationGO:00508631700.015
organic hydroxy compound metabolic processGO:19016152030.015
regulation of cell migrationGO:00303342190.015
rna processingGO:00063961050.015
adult behaviorGO:00305341350.015
stem cell differentiationGO:00488632680.015
activation of nf kappab inducing kinase activityGO:000725040.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
cellular response to organonitrogen compoundGO:00714171450.014
sequestering of calcium ionGO:0051208180.014
response to acid chemicalGO:00011011110.014
cell divisionGO:00513011200.014
protein maturationGO:00516041760.014
action potentialGO:0001508780.014
peptidyl serine modificationGO:0018209830.014
positive regulation of organelle organizationGO:00106381280.014
regulation of purine nucleotide catabolic processGO:00331211220.014
mrna processingGO:0006397630.014
small molecule biosynthetic processGO:00442831320.014
response to peptideGO:19016521360.014
cellular response to hormone stimulusGO:00328701500.014
carbohydrate metabolic processGO:00059752300.014
regulation of cell cycle phase transitionGO:1901987770.014
interspecies interaction between organismsGO:0044419830.014
organophosphate biosynthetic processGO:00904071220.014
regulation of vesicle mediated transportGO:00606271390.014
regulation of cellular response to stressGO:00801351590.014
posttranscriptional regulation of gene expressionGO:00106081550.014
Human Mouse
innate immune responseGO:00450871570.014
Mouse
anatomical structure homeostasisGO:00602491450.014
response to nutrient levelsGO:00316671090.014
purine nucleoside monophosphate metabolic processGO:0009126810.014
positive regulation of protein serine threonine kinase activityGO:00719021060.014
fat cell differentiationGO:00454441600.014
positive regulation of proteolysisGO:0045862850.014
regulation of wnt signaling pathwayGO:00301111230.014
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.014
protein acylationGO:0043543640.014
peptidyl tyrosine phosphorylationGO:00181081430.014
skeletal system developmentGO:00015013560.014
modification dependent macromolecule catabolic processGO:00436321330.014
inflammatory responseGO:00069542440.014
Mouse
regulation of nucleotide catabolic processGO:00308111220.014
connective tissue developmentGO:00614481790.013
translationGO:0006412930.013
Human
positive regulation of neuron differentiationGO:00456661410.013
purine ribonucleoside monophosphate metabolic processGO:0009167800.013
response to molecule of bacterial originGO:00022371430.013
Mouse
myosin filament assemblyGO:003103420.013
carbohydrate derivative biosynthetic processGO:19011371830.013
protein targetingGO:00066051430.013
epidermis developmentGO:00085441870.013
cellular response to biotic stimulusGO:0071216920.013
myeloid cell differentiationGO:00300992330.013
negative regulation of neuron deathGO:1901215980.013
cell growthGO:00160491300.013
sensory perceptionGO:00076002450.013
protein localization to nucleusGO:00345041210.013
peptidyl tyrosine modificationGO:00182121450.013
skeletal muscle organ developmentGO:00605381630.013
myelinationGO:0042552740.013
response to inorganic substanceGO:0010035960.013
developmental growth involved in morphogenesisGO:00605601380.013
positive regulation of hydrolase activityGO:00513451480.013
atp catabolic processGO:0006200550.013
locomotory behaviorGO:00076261950.013
glucose homeostasisGO:00425931280.013
response to hypoxiaGO:0001666580.013
sequestering of metal ionGO:0051238190.013
regulation of anatomical structure sizeGO:00900661780.013
skin developmentGO:00435882200.012
nuclear divisionGO:00002801580.012
cation transmembrane transportGO:00986552660.012
amide transportGO:00428861380.012
organic hydroxy compound transportGO:0015850930.012
cell cycle checkpointGO:0000075470.012
regulation of actin filament based processGO:0032970990.012
alcohol metabolic processGO:00060661160.012
regulation of lipid metabolic processGO:00192161180.012
cellular response to nutrient levelsGO:0031669640.012
wound healingGO:00420601570.012
regulation of cellular component sizeGO:00325351210.012
protein refoldingGO:004202610.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.012
regulation of proteolysisGO:00301621640.012
dna recombinationGO:0006310920.012
translesion synthesisGO:001998510.012
asymmetric stem cell divisionGO:009872230.012
rna interferenceGO:001624620.012
lateral inhibitionGO:004633110.012
multi multicellular organism processGO:00447061090.012
exocytosisGO:00068871210.012
divalent metal ion transportGO:00708381720.012
leukocyte mediated immunityGO:00024431740.012
male sex differentiationGO:00466611090.012
regulation of translationGO:0006417710.012
Human
epithelial cell developmentGO:00020641590.012
b cell activationGO:00421131610.012
regulation of interleukin 8 productionGO:003267730.012
positive regulation of cellular catabolic processGO:00313311480.012
regulation of cell morphogenesis involved in differentiationGO:00107691510.012
axonogenesisGO:00074092740.012
regulation of response to woundingGO:19030341890.012
activation of adenylate cyclase activityGO:000719040.012
endocytosisGO:00068971680.012
Mouse
digestive tract morphogenesisGO:00485461470.012
circadian rhythmGO:00076231140.012
protein importGO:00170381010.012
intracellular mrna localizationGO:000829840.012
regulation of cell motilityGO:20001452360.012
regulation of protein transportGO:00512231630.012
regulation of nucleotide metabolic processGO:00061401690.012
limb developmentGO:00601731660.012
compound eye developmentGO:004874910.012
blood circulationGO:00080151950.012
regulation of hormone levelsGO:00108172110.012
blood vessel morphogenesisGO:00485142850.012
negative regulation of mitotic cell cycleGO:0045930580.011
stem cell developmentGO:00488642190.011
lymphocyte mediated immunityGO:00024491390.011
interleukin 8 productionGO:003263740.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
myotube differentiationGO:00149021050.011
metal ion homeostasisGO:00550651890.011
development of primary sexual characteristicsGO:00451371430.011
cognitionGO:00508901490.011
zygotic determination of anterior posterior axis embryoGO:000735430.011
sensory organ morphogenesisGO:00905962420.011
morphogenesis of a branching epitheliumGO:00611381930.011
urogenital system developmentGO:00016552610.011
glycerolipid metabolic processGO:00464861220.011
negative regulation of neuron apoptotic processGO:0043524920.011
retrograde transport endosome to golgiGO:004214720.011
cristae formationGO:004240730.011
dna repairGO:00062811070.011
protein import into nucleusGO:0006606950.011
negative regulation of cell cycleGO:00457861230.011
meiotic cell cycleGO:00513211220.011
proteasomal protein catabolic processGO:0010498980.011
regulation of mrna metabolic processGO:1903311430.011
protein hydroxylationGO:001812640.011
regulation of bindingGO:00510981110.011
atp metabolic processGO:0046034750.011
regulation of nucleoside metabolic processGO:00091181300.011
glycerolipid biosynthetic processGO:0045017500.011
regulation of establishment of protein localizationGO:00702011810.011
meiotic nuclear divisionGO:00071261150.011
single organism cell adhesionGO:00986021560.011
negative regulation of transferase activityGO:0051348850.011
negative regulation of immune system processGO:00026832090.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
regulation of homeostatic processGO:00328441820.011
defense response to bacteriumGO:00427421190.011
antimicrobial peptide biosynthetic processGO:000277720.011
cytokinetic processGO:003250620.011
inorganic ion transmembrane transportGO:00986602340.011
peptidyl serine phosphorylationGO:0018105740.011
negative regulation of cell cycle processGO:0010948690.011
fertilizationGO:00095661270.011
carbohydrate homeostasisGO:00335001280.011
establishment of organelle localizationGO:00516561220.011
regulation of protein complex assemblyGO:0043254830.011
microtubule cytoskeleton organizationGO:00002261570.010
telencephalon developmentGO:00215371860.010
cellular response to lipidGO:00713961450.010
peptide transportGO:00158331330.010
localization within membraneGO:005166840.010
hematopoietic progenitor cell differentiationGO:00022441430.010
regulation of intracellular transportGO:00323861590.010
circadian regulation of gene expressionGO:0032922480.010
i kappab kinase nf kappab signalingGO:0007249850.010
oocyte constructionGO:000730820.010
adaptive immune responseGO:00022501550.010
protein ubiquitinationGO:00165671710.010
regulation of leukocyte differentiationGO:19021051590.010
negative regulation of nervous system developmentGO:00519611560.010
regulation of transcription from rna polymerase iii promoterGO:000635920.010
response to growth factorGO:00708481980.010
cellular response to peptideGO:1901653920.010
adult locomotory behaviorGO:0008344910.010
ensheathment of neuronsGO:0007272760.010
regulation of cytoskeleton organizationGO:00514931220.010
regulation of phospholipid biosynthetic processGO:007107130.010
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.010
cellular response to external stimulusGO:0071496880.010
carboxylic acid biosynthetic processGO:0046394860.010
organelle localizationGO:00516401790.010
ameboidal type cell migrationGO:00016671280.010
regulation of cell divisionGO:0051302760.010

Mapkapk5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
nervous system diseaseDOID:86300.025
musculoskeletal system diseaseDOID:1700.019
central nervous system diseaseDOID:33100.016
cardiomyopathyDOID:005070000.014
myopathyDOID:42300.014
muscle tissue diseaseDOID:6600.014
heart diseaseDOID:11400.014
muscular diseaseDOID:008000000.014
cardiovascular system diseaseDOID:128700.014
connective tissue diseaseDOID:6500.011
immune system diseaseDOID:291400.011
disease of cellular proliferationDOID:1456600.010
hematopoietic system diseaseDOID:7400.010