Mus musculus

26 known processes

Plcz1

phospholipase C, zeta 1

(Aliases: PLCzeta,MGC123405,MGC123406,1700041H07Rik)

Plcz1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203610.322
Mouse
regulation of cellular ketone metabolic processGO:0010565660.074
nucleobase containing small molecule metabolic processGO:00550863520.072
transmembrane transportGO:00550854120.071
Mouse
nitrogen compound transportGO:00717052710.069
cellular ketone metabolic processGO:0042180840.065
nucleoside phosphate metabolic processGO:00067533380.064
positive regulation of cellular amine metabolic processGO:003324050.063
positive regulation of protein modification processGO:00314012990.061
regulation of cellular amino acid metabolic processGO:000652150.060
ribose phosphate metabolic processGO:00196932910.059
organic anion transportGO:00157111370.058
purine ribonucleotide metabolic processGO:00091502900.057
sensory perceptionGO:00076002450.055
Mouse
nucleoside phosphate catabolic processGO:19012922220.053
nucleotide metabolic processGO:00091173320.053
metal ion homeostasisGO:00550651890.051
Mouse
membrane organizationGO:00610242450.050
anion transportGO:00068201770.049
male gamete generationGO:00482322850.049
adult behaviorGO:00305341350.048
nucleoside triphosphate catabolic processGO:00091432050.048
ribonucleotide catabolic processGO:00092612080.045
purine ribonucleotide catabolic processGO:00091542080.044
carbohydrate derivative catabolic processGO:19011362310.044
purine nucleotide metabolic processGO:00061633020.044
ribonucleoside metabolic processGO:00091192450.043
positive regulation of mapk cascadeGO:00434101700.043
macromolecule catabolic processGO:00090572810.043
protein catabolic processGO:00301632210.043
purine containing compound metabolic processGO:00725213110.042
purine nucleoside metabolic processGO:00422782410.042
purine containing compound catabolic processGO:00725232130.042
regulation of kinase activityGO:00435492490.042
stem cell differentiationGO:00488632680.042
regulation of hydrolase activityGO:00513362460.042
cellular nitrogen compound catabolic processGO:00442702800.041
positive regulation of protein phosphorylationGO:00019342420.041
purine ribonucleoside metabolic processGO:00461282410.040
carbohydrate metabolic processGO:00059752300.040
cation transmembrane transportGO:00986552660.039
Mouse
leukocyte differentiationGO:00025213420.039
Mouse
nucleoside metabolic processGO:00091162460.037
cellular amine metabolic processGO:0044106440.037
cation transportGO:00068123990.037
organophosphate catabolic processGO:00464342320.037
response to light stimulusGO:00094161350.036
ossificationGO:00015032160.036
regulation of transferase activityGO:00513382630.036
aromatic compound catabolic processGO:00194392860.036
glycosyl compound catabolic processGO:19016582060.036
heterocycle catabolic processGO:00467002800.035
inorganic ion transmembrane transportGO:00986602340.035
Mouse
blood vessel morphogenesisGO:00485142850.034
Mouse
cell adhesionGO:00071553290.033
ribonucleoside triphosphate metabolic processGO:00091992200.033
organic cyclic compound catabolic processGO:19013612950.033
purine nucleoside triphosphate catabolic processGO:00091462030.033
response to radiationGO:00093141650.033
ribonucleotide metabolic processGO:00092592910.033
positive regulation of cellular amino acid metabolic processGO:004576430.033
organonitrogen compound catabolic processGO:19015652640.032
cation homeostasisGO:00550802120.031
Mouse
regulation of cellular amine metabolic processGO:0033238200.031
cellular chemical homeostasisGO:00550822150.031
Mouse
purine ribonucleoside triphosphate metabolic processGO:00092052200.031
regulation of purine nucleotide metabolic processGO:19005421690.031
muscle contractionGO:00069361010.030
nucleoside triphosphate metabolic processGO:00091412300.030
cellular homeostasisGO:00197252400.030
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092071990.030
cytoplasmic transportGO:00164822340.030
Mouse
nucleotide catabolic processGO:00091662170.030
purine nucleoside triphosphate metabolic processGO:00091442260.029
purine nucleotide catabolic processGO:00061952110.028
nucleoside catabolic processGO:00091642060.028
cellular divalent inorganic cation homeostasisGO:00725031270.028
Mouse
cellular amino acid metabolic processGO:00065201030.028
microtubule based processGO:00070172360.028
regulation of membrane potentialGO:00423911920.028
action potentialGO:0001508780.027
glycosyl compound metabolic processGO:19016572460.027
cellular metal ion homeostasisGO:00068751510.027
Mouse
regulation of cell projection organizationGO:00313442060.027
purine nucleoside catabolic processGO:00061522050.027
regulation of ion transportGO:00432692150.026
Mouse
response to growth factorGO:00708481980.026
positive regulation of kinase activityGO:00336741550.026
cellular ion homeostasisGO:00068731650.026
Mouse
actin cytoskeleton organizationGO:00300362200.026
muscle system processGO:00030121410.026
regulation of actin filament based processGO:0032970990.025
positive regulation of transferase activityGO:00513471670.025
regulation of homeostatic processGO:00328441820.025
Mouse
regulation of transmembrane transportGO:00347621280.025
Mouse
divalent inorganic cation transportGO:00725111780.025
purine ribonucleoside catabolic processGO:00461302050.025
ear developmentGO:00435832000.025
peptide transportGO:00158331330.025
amide transportGO:00428861380.025
regulation of cell migrationGO:00303342190.024
circulatory system processGO:00030131970.024
regulation of mapk cascadeGO:00434082480.024
positive regulation of cellular catabolic processGO:00313311480.024
peptidyl amino acid modificationGO:00181933360.024
Mouse
regulation of muscle system processGO:0090257800.023
cellular response to organonitrogen compoundGO:00714171450.023
inorganic cation transmembrane transportGO:00986622070.023
Mouse
positive regulation of protein kinase activityGO:00458601440.023
regulation of organelle organizationGO:00330432890.023
carboxylic acid transportGO:00469421000.023
amine metabolic processGO:0009308450.023
regulation of ion transmembrane transportGO:00347651190.023
Mouse
regionalizationGO:00030023370.022
protein modification by small protein conjugationGO:00324461870.022
cytokine productionGO:00018163190.022
regulation of hormone levelsGO:00108172110.022
response to transforming growth factor betaGO:0071559880.022
regulation of metal ion transportGO:00109591060.022
Mouse
ribonucleoside triphosphate catabolic processGO:00092031990.022
regulation of blood circulationGO:1903522930.022
learning or memoryGO:00076111480.022
cognitionGO:00508901490.022
positive regulation of hydrolase activityGO:00513451480.022
multicellular organismal signalingGO:0035637910.021
regulation of cellular component biogenesisGO:00440871810.021
leukocyte proliferationGO:00706611720.021
Mouse
regulation of secretionGO:00510462740.021
regulation of cell adhesionGO:00301551540.021
homeostasis of number of cellsGO:00488722100.021
response to organic cyclic compoundGO:00140701980.020
single fertilizationGO:0007338820.020
regulation of defense responseGO:00313472330.020
negative regulation of growthGO:0045926990.020
locomotory behaviorGO:00076261950.020
skeletal system developmentGO:00015013560.020
positive regulation of cell developmentGO:00107202370.020
skin developmentGO:00435882200.020
carbohydrate derivative biosynthetic processGO:19011371830.020
negative regulation of immune system processGO:00026832090.020
Mouse
regulation of nucleotide metabolic processGO:00061401690.020
hematopoietic progenitor cell differentiationGO:00022441430.020
mapk cascadeGO:00001652810.020
regulation of protein kinase activityGO:00458592320.020
g protein coupled receptor signaling pathwayGO:00071862430.020
Mouse
positive regulation of cell migrationGO:00303351090.020
extracellular matrix organizationGO:00301981470.020
regulation of secretion by cellGO:19035302490.019
cytosolic calcium ion homeostasisGO:0051480700.019
Mouse
regulation of cellular catabolic processGO:00313292420.019
ras protein signal transductionGO:0007265770.019
transmission of nerve impulseGO:0019226760.019
embryonic organ morphogenesisGO:00485622760.019
multicellular organism growthGO:00352641610.019
monocarboxylic acid metabolic processGO:00327871910.019
axonogenesisGO:00074092740.019
developmental maturationGO:00217001930.019
regulation of purine nucleotide catabolic processGO:00331211220.019
cellular response to transforming growth factor beta stimulusGO:0071560880.019
regulation of anatomical structure sizeGO:00900661780.019
positive regulation of cell motilityGO:20001471160.019
dephosphorylationGO:00163111290.019
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.018
protein modification by small protein conjugation or removalGO:00706472070.018
regulation of cytoskeleton organizationGO:00514931220.018
t cell activationGO:00421102890.018
ribonucleoside catabolic processGO:00424542060.018
organic acid transportGO:00158491010.018
sequestering of calcium ionGO:0051208180.018
Mouse
adaptive immune responseGO:00022501550.018
nuclear transportGO:00511691390.018
regulation of protein catabolic processGO:00421761080.018
establishment of protein localization to organelleGO:00725941180.018
adult locomotory behaviorGO:0008344910.018
intracellular protein transportGO:00068862040.018
cellular calcium ion homeostasisGO:00068741190.018
Mouse
cell type specific apoptotic processGO:00972852680.018
nucleocytoplasmic transportGO:00069131390.018
regulation of cell activationGO:00508652890.018
calcium ion transportGO:00068161590.018
muscle tissue developmentGO:00605373080.017
regulation of muscle contractionGO:0006937490.017
spermatogenesisGO:00072832840.017
digestive tract developmentGO:00485651900.017
negative regulation of protein metabolic processGO:00512482820.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.017
regulation of system processGO:00440572000.017
endocytosisGO:00068971680.017
sequestering of metal ionGO:0051238190.017
Mouse
small gtpase mediated signal transductionGO:0007264970.017
t cell differentiationGO:00302171740.017
positive regulation of nervous system developmentGO:00519622210.017
respiratory system developmentGO:00605411900.017
regulation of protein transportGO:00512231630.017
response to organonitrogen compoundGO:00102432460.017
positive regulation of protein serine threonine kinase activityGO:00719021060.017
heart morphogenesisGO:00030071780.017
peptide hormone secretionGO:00300721090.017
peptide secretionGO:00027901140.017
anion transmembrane transportGO:0098656710.016
myeloid cell differentiationGO:00300992330.016
regulation of cellular component sizeGO:00325351210.016
divalent inorganic cation homeostasisGO:00725071380.016
Mouse
glycerolipid metabolic processGO:00464861220.016
Mouse
synaptic transmissionGO:00072683290.016
Mouse
cellular response to lipidGO:00713961450.016
cellular response to growth factor stimulusGO:00713631970.016
neural precursor cell proliferationGO:00613511210.016
positive regulation of nucleotide metabolic processGO:00459811140.016
positive regulation of programmed cell deathGO:00430682180.016
cellular protein complex assemblyGO:00436231160.016
exocytosisGO:00068871210.016
Mouse
forebrain developmentGO:00309003020.016
regulation of cell motilityGO:20001452360.016
negative regulation of cellular component organizationGO:00511291940.016
carbohydrate transportGO:0008643620.016
response to peptide hormoneGO:00434341270.016
rhodopsin mediated signaling pathwayGO:001605640.016
positive regulation of neuron differentiationGO:00456661410.016
calcium ion homeostasisGO:00550741270.015
Mouse
microtubule based movementGO:0007018840.015
regulation of protein complex assemblyGO:0043254830.015
sensory perception of light stimulusGO:0050953540.015
regulation of leukocyte differentiationGO:19021051590.015
glycoprotein metabolic processGO:00091001160.015
regulation of lymphocyte activationGO:00512492400.015
regulation of proteolysisGO:00301621640.015
stem cell developmentGO:00488642190.015
regulation of ossificationGO:00302781120.015
leukocyte homeostasisGO:0001776790.015
protein processingGO:00164851630.015
regulation of cell cycleGO:00517262810.015
organic hydroxy compound metabolic processGO:19016152030.015
Mouse
sterol homeostasisGO:0055092450.015
epithelial cell developmentGO:00020641590.015
myotube differentiationGO:00149021050.015
kidney developmentGO:00018222130.015
protein localization to organelleGO:00333651850.015
protein maturationGO:00516041760.015
tissue remodelingGO:00487711020.015
renal system developmentGO:00720012250.015
protein ubiquitinationGO:00165671710.015
gtp metabolic processGO:00460391440.015
lymphocyte proliferationGO:00466511640.015
Mouse
positive regulation of apoptotic processGO:00430652170.014
positive regulation of nucleoside metabolic processGO:0045979910.014
maintenance of locationGO:0051235890.014
Mouse
organophosphate biosynthetic processGO:00904071220.014
Mouse
response to lipopolysaccharideGO:00324961280.014
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.014
regulation of establishment of protein localizationGO:00702011810.014
lymphocyte differentiationGO:00300982420.014
Mouse
response to amino acidGO:0043200370.014
negative regulation of protein modification processGO:00314001630.014
neuromuscular processGO:0050905990.014
neuron apoptotic processGO:00514021420.014
regulation of neuron differentiationGO:00456642810.014
neuron deathGO:00709971540.014
monosaccharide metabolic processGO:00059961060.014
dna metabolic processGO:00062593030.014
cell substrate adhesionGO:00315891300.014
lipid transportGO:0006869980.014
immune effector processGO:00022523210.014
Mouse
regulation of postsynaptic membrane potentialGO:0060078480.014
cellular protein catabolic processGO:00442571550.014
negative regulation of phosphorus metabolic processGO:00105631840.014
positive regulation of purine nucleotide catabolic processGO:0033123880.014
hormone secretionGO:00468791280.014
negative regulation of phosphate metabolic processGO:00459361840.014
positive regulation of nucleotide catabolic processGO:0030813880.014
cellular macromolecule catabolic processGO:00442652060.014
regulation of nucleotide catabolic processGO:00308111220.014
spleen developmentGO:0048536390.014
regulation of leukocyte proliferationGO:00706631210.013
protein localization to membraneGO:00726571080.013
response to extracellular stimulusGO:00099911270.013
heart processGO:0003015940.013
neuronal action potentialGO:0019228540.013
sensory perception of soundGO:0007605970.013
t cell proliferationGO:00420981200.013
biomineral tissue developmentGO:0031214640.013
regulation of protein localizationGO:00328802310.013
camera type eye developmentGO:00430102660.013
cell growthGO:00160491300.013
transforming growth factor beta receptor signaling pathwayGO:0007179710.013
regulation of lymphocyte proliferationGO:00506701170.013
positive regulation of cell adhesionGO:0045785800.013
sulfur compound metabolic processGO:00067901000.013
neuron neuron synaptic transmissionGO:0007270690.013
Mouse
respiratory tube developmentGO:00303231670.013
sterol metabolic processGO:0016125580.013
engulfment of apoptotic cellGO:004365230.013
regulation of protein serine threonine kinase activityGO:00719001570.013
regulation of inflammatory responseGO:00507271470.013
photoreceptor cell morphogenesisGO:000859430.013
gtp catabolic processGO:00061841430.013
regulation of t cell activationGO:00508631700.013
response to temperature stimulusGO:0009266550.012
organelle localizationGO:00516401790.012
glycosylationGO:0070085620.012
negative regulation of molecular functionGO:00440922580.012
regulation of cytoplasmic transportGO:19036491120.012
mesenchymal cell differentiationGO:00487621070.012
purine ribonucleoside monophosphate metabolic processGO:0009167800.012
detection of stimulusGO:0051606840.012
eosinophil migrationGO:007267730.012
regulation of stem cell proliferationGO:0072091780.012
regulation of nucleoside metabolic processGO:00091181300.012
gland developmentGO:00487323300.012
extracellular structure organizationGO:00430621480.012
skeletal muscle organ developmentGO:00605381630.012
epidermis developmentGO:00085441870.012
detection of external stimulusGO:0009581610.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
sensory organ morphogenesisGO:00905962420.012
mitochondrion organizationGO:00070051340.012
protein localization to nucleusGO:00345041210.012
endomembrane system organizationGO:00102561470.012
positive regulation of protein catabolic processGO:0045732600.012
cellular response to hormone stimulusGO:00328701500.012
regulation of eosinophil migrationGO:200041620.012
positive regulation of defense responseGO:00313491240.012
chemotaxisGO:00069352470.012
response to peptideGO:19016521360.012
protein glycosylationGO:0006486550.012
detection of abiotic stimulusGO:0009582600.012
midgut developmentGO:000749440.012
protein importGO:00170381010.012
striated muscle tissue developmentGO:00147062930.012
regulation of heart contractionGO:0008016770.012
skeletal system morphogenesisGO:00487052030.012
microtubule cytoskeleton organizationGO:00002261570.012
regulation of neuron deathGO:19012141340.012
multi multicellular organism processGO:00447061090.012
regulation of peptide transportGO:0090087910.012
insulin secretionGO:0030073890.012
peptidyl tyrosine modificationGO:00182121450.012
bone mineralizationGO:0030282540.011
tissue homeostasisGO:00018941150.011
sodium ion transportGO:0006814730.011
response to acid chemicalGO:00011011110.011
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.011
sensory perception of chemical stimulusGO:0007606510.011
Mouse
actin filament polymerizationGO:0030041440.011
negative regulation of cell proliferationGO:00082852960.011
positive regulation of cell activationGO:00508671580.011
stem cell proliferationGO:00720891170.011
cellular response to external stimulusGO:0071496880.011
rho protein signal transductionGO:0007266320.011
negative regulation of neuron differentiationGO:00456651010.011
appendage developmentGO:00487361660.011
spermatid developmentGO:00072861080.011
regulation of cell morphogenesis involved in differentiationGO:00107691510.011
telencephalon developmentGO:00215371860.011
olfactory learningGO:000835520.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
negative regulation of neuron deathGO:1901215980.011
apoptotic signaling pathwayGO:00971903060.011
nucleoside monophosphate metabolic processGO:0009123850.011
steroid metabolic processGO:00082021190.011
protein polymerizationGO:0051258570.011
negative regulation of muscle contractionGO:0045932120.011
regulation of cellular response to growth factor stimulusGO:0090287820.011
bone developmentGO:00603481200.011
neuron migrationGO:00017641220.011
anatomical structure homeostasisGO:00602491450.011
digestive system developmentGO:00551232000.011
positive regulation of thymocyte migrationGO:200041220.011
regulation of actin cytoskeleton organizationGO:0032956840.011
cell divisionGO:00513011200.011
synapse organizationGO:00508081250.011
ribonucleoside monophosphate catabolic processGO:0009158570.011
developmental cell growthGO:0048588840.011
angiogenesisGO:00015252010.011
Mouse
smooth muscle contractionGO:0006939440.011
carbohydrate homeostasisGO:00335001280.011
positive regulation of membrane protein ectodomain proteolysisGO:005104430.010
muscle cell differentiationGO:00426922610.010
divalent metal ion transportGO:00708381720.010
connective tissue developmentGO:00614481790.010
posttranscriptional regulation of gene expressionGO:00106081550.010
nuclear importGO:0051170950.010
multicellular organismal homeostasisGO:00488711640.010
regulation of organ morphogenesisGO:20000271440.010
spermatid differentiationGO:00485151150.010
immune response regulating signaling pathwayGO:00027641250.010
Mouse
cellular response to extracellular stimulusGO:0031668810.010
positive regulation of lymphocyte activationGO:00512511400.010
positive regulation of inflammatory responseGO:0050729470.010
positive regulation of leukocyte differentiationGO:1902107860.010
regulation of leukocyte apoptotic processGO:2000106560.010
lung developmentGO:00303241640.010
positive regulation of eosinophil migrationGO:200041820.010
atp catabolic processGO:0006200550.010
positive regulation of proteolysisGO:0045862850.010
cellular response to peptideGO:1901653920.010
regulation of vesicle mediated transportGO:00606271390.010
negative regulation of neuron apoptotic processGO:0043524920.010
protein import into nucleusGO:0006606950.010
single organism cell adhesionGO:00986021560.010
visual learningGO:0008542440.010
organonitrogen compound biosynthetic processGO:19015661920.010
cardiac muscle contractionGO:0060048320.010
mesenchyme developmentGO:00604851520.010
glucose metabolic processGO:0006006920.010
response to steroid hormoneGO:0048545560.010
digestionGO:0007586400.010
neuron projection guidanceGO:00974851410.010
ribonucleoside monophosphate metabolic processGO:0009161800.010
gliogenesisGO:00420631410.010
glial cell developmentGO:0021782540.010

Plcz1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.046
nervous system diseaseDOID:86300.046
sensory system diseaseDOID:005015500.026
eye and adnexa diseaseDOID:149200.020
eye diseaseDOID:561400.016
retinal diseaseDOID:567900.011
retinal degenerationDOID:846600.010