Mus musculus

216 known processes

Pink1

PTEN induced putative kinase 1

(Aliases: AU042772,1190006F07Rik,BRPK,AW557854,mFLJ00387)

Pink1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143420.099
cofactor metabolic processGO:0051186800.069
cellular ketone metabolic processGO:0042180840.057
camera type eye developmentGO:00430102660.057
regulation of cellular ketone metabolic processGO:0010565660.054
organic acid biosynthetic processGO:0016053860.049
cellular amino acid metabolic processGO:00065201030.047
protein catabolic processGO:00301632210.045
Fly
lipid biosynthetic processGO:00086101790.045
fat cell differentiationGO:00454441600.044
regulation of fatty acid biosynthetic processGO:0042304120.041
monocarboxylic acid biosynthetic processGO:0072330610.041
transmembrane transportGO:00550854120.040
regulation of cellular amine metabolic processGO:0033238200.038
regulation of cell cycle processGO:00105641600.038
dna metabolic processGO:00062593030.037
fatty acid metabolic processGO:00066311210.035
cellular response to dna damage stimulusGO:00069742070.034
peptidyl amino acid modificationGO:00181933360.034
Human
response to radiationGO:00093141650.032
muscle tissue developmentGO:00605373080.032
nitrogen compound transportGO:00717052710.031
macromolecule catabolic processGO:00090572810.031
Fly
coenzyme metabolic processGO:0006732520.031
response to light stimulusGO:00094161350.031
cellular response to cytokine stimulusGO:00713451890.030
amine metabolic processGO:0009308450.030
negative regulation of cellular protein metabolic processGO:00322692470.030
monosaccharide metabolic processGO:00059961060.029
thioester biosynthetic processGO:003538470.028
generation of precursor metabolites and energyGO:00060911030.028
hexose metabolic processGO:0019318980.028
cellular carbohydrate metabolic processGO:00442621190.027
purine nucleotide metabolic processGO:00061633020.027
striated muscle tissue developmentGO:00147062930.027
anatomical structure homeostasisGO:00602491450.027
regulation of lipid metabolic processGO:00192161180.026
energy derivation by oxidation of organic compoundsGO:0015980770.026
regulation of cellular amino acid metabolic processGO:000652150.026
small molecule biosynthetic processGO:00442831320.025
cellular response to hormone stimulusGO:00328701500.025
response to peptideGO:19016521360.025
chromatin organizationGO:00063252060.025
stem cell differentiationGO:00488632680.025
carbohydrate metabolic processGO:00059752300.025
regulation of homeostatic processGO:00328441820.025
negative regulation of protein modification processGO:00314001630.025
carboxylic acid biosynthetic processGO:0046394860.024
cellular lipid metabolic processGO:00442553230.024
protein localization to organelleGO:00333651850.024
positive regulation of cellular amine metabolic processGO:003324050.024
regulation of fatty acid oxidationGO:0046320100.023
response to organonitrogen compoundGO:00102432460.023
response to extracellular stimulusGO:00099911270.023
cellular amine metabolic processGO:0044106440.023
response to peptide hormoneGO:00434341270.023
mitotic cell cycleGO:00002781950.023
fat soluble vitamin biosynthetic processGO:004236240.022
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.022
regulation of transferase activityGO:00513382630.022
cation transmembrane transportGO:00986552660.022
thioester metabolic processGO:0035383190.022
sensory perceptionGO:00076002450.022
positive regulation of cell deathGO:00109422240.021
Human
chemotaxisGO:00069352470.021
Worm
acyl coa biosynthetic processGO:007161670.021
cation transportGO:00068123990.021
regulation of neuron differentiationGO:00456642810.020
fatty acid biosynthetic processGO:0006633410.020
negative regulation of cell cycleGO:00457861230.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
regulation of cell cycleGO:00517262810.020
nucleobase containing small molecule metabolic processGO:00550863520.020
maintenance of locationGO:0051235890.020
positive regulation of programmed cell deathGO:00430682180.020
Human
inorganic ion transmembrane transportGO:00986602340.020
axonogenesisGO:00074092740.019
Worm
regulation of fatty acid metabolic processGO:0019217280.019
regulation of organelle organizationGO:00330432890.019
Human Fly
sensory organ morphogenesisGO:00905962420.019
aromatic compound catabolic processGO:00194392860.019
connective tissue developmentGO:00614481790.019
cellular macromolecule catabolic processGO:00442652060.019
Fly
skeletal muscle organ developmentGO:00605381630.018
heart morphogenesisGO:00030071780.018
negative regulation of cellular component organizationGO:00511291940.018
Fly
chromatin modificationGO:00165681870.018
regulation of circadian sleep wake cycle sleepGO:004518730.018
developmental growth involved in morphogenesisGO:00605601380.018
Worm
action potentialGO:0001508780.018
reactive oxygen species metabolic processGO:0072593840.018
transmission of nerve impulseGO:0019226760.018
cellular response to organonitrogen compoundGO:00714171450.018
organic hydroxy compound metabolic processGO:19016152030.018
coenzyme biosynthetic processGO:0009108230.017
negative regulation of cellular amino acid metabolic processGO:004576300.017
substantia nigra developmentGO:002176220.017
circulatory system processGO:00030131970.017
pyrimidine containing compound catabolic processGO:007252930.017
regulation of ion transportGO:00432692150.017
negative regulation of organelle organizationGO:0010639900.017
Fly
organelle fissionGO:00482851700.017
Fly
negative regulation of cell proliferationGO:00082852960.017
regulation of circadian sleep wake cycleGO:004274930.017
acetyl coa biosynthetic process from pyruvateGO:000608630.017
stem cell maintenanceGO:00198271300.016
embryonic organ morphogenesisGO:00485622760.016
ras protein signal transductionGO:0007265770.016
polysaccharide metabolic processGO:0005976390.016
histone modificationGO:00165701590.016
rhythmic processGO:00485111740.016
nucleocytoplasmic transportGO:00069131390.016
negative regulation of protein metabolic processGO:00512482820.016
glucose metabolic processGO:0006006920.016
mitotic cell cycle processGO:19030471590.016
male gamete generationGO:00482322850.015
cation homeostasisGO:00550802120.015
translationGO:0006412930.015
fertilizationGO:00095661270.015
digestive system developmentGO:00551232000.015
t cell activationGO:00421102890.015
inorganic cation transmembrane transportGO:00986622070.015
positive regulation of apoptotic processGO:00430652170.015
Human
microtubule based processGO:00070172360.015
carbohydrate biosynthetic processGO:0016051740.015
blood circulationGO:00080151950.015
methylationGO:00322591340.015
apoptotic signaling pathwayGO:00971903060.015
hexose biosynthetic processGO:0019319390.014
covalent chromatin modificationGO:00165691630.014
regulation of membrane potentialGO:00423911920.014
Human
defense response to other organismGO:00985421970.014
cartilage developmentGO:00512161400.014
dephosphorylationGO:00163111290.014
cellular nitrogen compound catabolic processGO:00442702800.014
homeostasis of number of cellsGO:00488722100.014
Zebrafish
regulation of transmembrane transportGO:00347621280.014
nucleotide metabolic processGO:00091173320.014
heart contractionGO:0060047930.014
cellular response to nutrient levelsGO:0031669640.014
cellular response to growth factor stimulusGO:00713631970.013
Zebrafish
stem cell developmentGO:00488642190.013
cellular homeostasisGO:00197252400.013
positive regulation of protein modification processGO:00314012990.013
negative regulation of cellular amine metabolic processGO:003323910.013
respiratory system developmentGO:00605411900.013
cytokine productionGO:00018163190.013
acetyl coa biosynthetic processGO:000608550.013
meiotic nuclear divisionGO:00071261150.013
blood vessel morphogenesisGO:00485142850.013
adiponectin activated signaling pathwayGO:003321140.013
cardiac muscle contractionGO:0060048320.013
regulation of kinase activityGO:00435492490.013
cell type specific apoptotic processGO:00972852680.013
organic acid catabolic processGO:0016054510.013
response to insulinGO:00328681000.013
autophagyGO:0006914450.013
Human Fly
response to growth factorGO:00708481980.013
Zebrafish
mitochondrion organizationGO:00070051340.013
Human Zebrafish Worm Fly
nuclear divisionGO:00002801580.013
regulation of chromosome organizationGO:0033044830.013
positive regulation of cell developmentGO:00107202370.013
digestive tract developmentGO:00485651900.013
regulation of voltage gated calcium channel activityGO:190138540.013
cellular response to lipidGO:00713961450.013
alpha amino acid metabolic processGO:1901605590.012
steroid metabolic processGO:00082021190.012
response to acid chemicalGO:00011011110.012
anion transportGO:00068201770.012
neuron apoptotic processGO:00514021420.012
protein ubiquitinationGO:00165671710.012
Human Fly
cellular response to external stimulusGO:0071496880.012
muscle cell differentiationGO:00426922610.012
negative regulation of nervous system developmentGO:00519611560.012
carboxylic acid transportGO:00469421000.012
chromosome segregationGO:0007059480.012
gland developmentGO:00487323300.012
cellular response to peptide hormone stimulusGO:0071375920.012
glucose homeostasisGO:00425931280.012
protein methylationGO:0006479810.012
small gtpase mediated signal transductionGO:0007264970.012
cellular response to acid chemicalGO:0071229680.012
monosaccharide biosynthetic processGO:0046364440.012
negative regulation of molecular functionGO:00440922580.012
limb developmentGO:00601731660.012
nucleoside phosphate catabolic processGO:19012922220.012
forebrain developmentGO:00309003020.011
multicellular organismal signalingGO:0035637910.011
gene silencingGO:0016458380.011
epithelial tube formationGO:00721751300.011
detection of external stimulusGO:0009581610.011
positive regulation of organelle organizationGO:00106381280.011
Human Fly
retina development in camera type eyeGO:00600411190.011
regulation of interleukin 8 productionGO:003267730.011
posttranscriptional regulation of gene expressionGO:00106081550.011
myeloid cell homeostasisGO:00022621140.011
Zebrafish
germ cell developmentGO:00072811850.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
muscle contractionGO:00069361010.011
ion transmembrane transportGO:00342203610.011
endomembrane system organizationGO:00102561470.011
organic anion transportGO:00157111370.011
microtubule cytoskeleton organizationGO:00002261570.011
regulation of defense response to bacteriumGO:190042430.011
g protein coupled receptor signaling pathwayGO:00071862430.011
ribonucleotide biosynthetic processGO:0009260590.011
spermatogenesisGO:00072832840.011
organic cyclic compound catabolic processGO:19013612950.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
regulation of carbohydrate metabolic processGO:0006109750.011
organonitrogen compound biosynthetic processGO:19015661920.011
meiosis iGO:0007127600.011
l glutamate import into cellGO:199012330.011
protein localization to nucleusGO:00345041210.011
carbohydrate transportGO:0008643620.011
meiotic cell cycleGO:00513211220.011
regulation of epithelial cell proliferationGO:00506781410.010
regulation of hormone levelsGO:00108172110.010
macromolecule methylationGO:00434141200.010
regulation of chromatin modificationGO:1903308570.010
regulation of fat cell differentiationGO:0045598810.010
male meiosis iGO:0007141160.010
nuclear transportGO:00511691390.010
sodium ion transportGO:0006814730.010
acyl coa metabolic processGO:0006637190.010
negative regulation of phosphate metabolic processGO:00459361840.010
lateral inhibitionGO:004633110.010
coenzyme catabolic processGO:000910950.010
cytokine mediated signaling pathwayGO:00192211150.010
regulation of system processGO:00440572000.010
multi multicellular organism processGO:00447061090.010
positive regulation of fatty acid oxidationGO:004632140.010
macromolecular complex disassemblyGO:0032984430.010
regulation of cellular catabolic processGO:00313292420.010
response to inorganic substanceGO:0010035960.010
Human
appendage developmentGO:00487361660.010
tube formationGO:00351481400.010
locomotory behaviorGO:00076261950.010
regulation of acyl coa biosynthetic processGO:005081240.010
mapk cascadeGO:00001652810.010
negative regulation of phosphorus metabolic processGO:00105631840.010

Pink1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
Human
nervous system diseaseDOID:86300.028
Human
eye and adnexa diseaseDOID:149200.027
sensory system diseaseDOID:005015500.027
eye diseaseDOID:561400.027
disease of metabolismDOID:001466700.019
inherited metabolic disorderDOID:65500.015
retinal diseaseDOID:567900.014