IMP: Integrative Multi-species Prediction

Mus musculus

15 known processes

Gjb4

gap junction protein, beta 4

(Aliases: Gjb-4,Cnx30.3,Cx30.3)

Entrez: 14621
Ensembl: ENSMUSG00000046623
UniProtKB: Q02738
UniProtKB: Q8C677

Process Predictions
Disease Predictions

Gjb4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
epithelial tube morphogenesis	GO:0060562	303	0.621	Mouse
sensory organ morphogenesis	GO:0090596	242	0.593	Mouse
stem cell development	GO:0048864	219	0.559
hair follicle development	GO:0001942	85	0.504
limb development	GO:0060173	166	0.491	Mouse
av node cell to bundle of his cell communication	GO:0086067	2	0.426	Mouse
wound healing	GO:0042060	157	0.382	Mouse
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.344
molting cycle	GO:0042303	90	0.341
cell fate commitment	GO:0045165	210	0.330
atrial ventricular junction remodeling	GO:0003294	2	0.311	Mouse
epithelial cell development	GO:0002064	159	0.301	Mouse
neuron migration	GO:0001764	122	0.296	Mouse
regulation of membrane depolarization during action potential	GO:0098902	1	0.263	Mouse
hair follicle morphogenesis	GO:0031069	29	0.246
hair cycle	GO:0042633	90	0.245
embryonic organ morphogenesis	GO:0048562	276	0.232	Mouse
ureteric bud development	GO:0001657	94	0.231
regulation of renin secretion into blood stream	GO:1900133	4	0.224	Mouse
sa node cell action potential	GO:0086015	4	0.219	Mouse
stem cell maintenance	GO:0019827	130	0.217
paraxial mesodermal cell fate commitment	GO:0048343	2	0.203
stem cell differentiation	GO:0048863	268	0.194
placenta development	GO:0001890	140	0.193	Mouse
regulation of organ morphogenesis	GO:2000027	144	0.189
lens development in camera type eye	GO:0002088	62	0.188	Mouse
cell type specific apoptotic process	GO:0097285	268	0.183
nephron epithelium development	GO:0072009	92	0.182
spermatogenesis	GO:0007283	284	0.178
regulation of cellular ketone metabolic process	GO:0010565	66	0.177
branching involved in ureteric bud morphogenesis	GO:0001658	56	0.172
keratinocyte differentiation	GO:0030216	48	0.171
blood vessel morphogenesis	GO:0048514	285	0.171	Mouse
regionalization	GO:0003002	337	0.171
morphogenesis of a branching structure	GO:0001763	203	0.171
appendage development	GO:0048736	166	0.156	Mouse
establishment of planar polarity involved in nephron morphogenesis	GO:0072046	1	0.155
skin morphogenesis	GO:0043589	38	0.155
epithelial cell proliferation	GO:0050673	174	0.152
epidermis development	GO:0008544	187	0.150
regulation of heart rate	GO:0002027	36	0.150	Mouse
regulation of anatomical structure size	GO:0090066	178	0.145	Mouse
nephron epithelium morphogenesis	GO:0072088	68	0.144
central nervous system vasculogenesis	GO:0022009	3	0.144
striated muscle contraction	GO:0006941	45	0.140
extrinsic apoptotic signaling pathway	GO:0097191	126	0.140
epidermis morphogenesis	GO:0048730	33	0.139
cell differentiation involved in embryonic placenta development	GO:0060706	26	0.138	Mouse
kidney development	GO:0001822	213	0.136
embryonic placenta development	GO:0001892	98	0.136	Mouse
cellular response to hormone stimulus	GO:0032870	150	0.133
cytokine mediated signaling pathway	GO:0019221	115	0.133
axon guidance	GO:0007411	141	0.132
gland development	GO:0048732	330	0.131
urogenital system development	GO:0001655	261	0.128
salivary gland morphogenesis	GO:0007435	33	0.128
paraxial mesodermal cell differentiation	GO:0048342	2	0.128
lung induction	GO:0060492	3	0.127
kidney morphogenesis	GO:0060993	83	0.126
cellular response to cytokine stimulus	GO:0071345	189	0.125
hepatocyte apoptotic process	GO:0097284	11	0.124
cellular ketone metabolic process	GO:0042180	84	0.123
intermediate filament cytoskeleton organization	GO:0045104	26	0.123
skin development	GO:0043588	220	0.122
axonogenesis	GO:0007409	274	0.121
developmental programmed cell death	GO:0010623	41	0.121
morphogenesis of a branching epithelium	GO:0061138	193	0.121
negative regulation of protein processing	GO:0010955	79	0.120
branching morphogenesis of an epithelial tube	GO:0048754	159	0.119
midbrain hindbrain boundary maturation	GO:0021732	1	0.119
protein processing	GO:0016485	163	0.118
hindbrain development	GO:0030902	128	0.118
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045899	2	0.117
mesenchymal cell differentiation	GO:0048762	107	0.116
muscle cell differentiation	GO:0042692	261	0.115
forebrain development	GO:0030900	302	0.114
regulation of secretion	GO:0051046	274	0.111	Mouse
mesenchyme development	GO:0060485	152	0.111
male gamete generation	GO:0048232	285	0.110
muscle system process	GO:0003012	141	0.105
cerebellum formation	GO:0021588	1	0.105
kidney epithelium development	GO:0072073	121	0.105
hindbrain formation	GO:0021576	1	0.104
negative regulation of protein maturation	GO:1903318	79	0.103
protein localization to membrane	GO:0072657	108	0.103
somatotropin secreting cell differentiation	GO:0060126	4	0.103
mesonephric tubule development	GO:0072164	94	0.102
positive regulation of homeostatic process	GO:0032846	64	0.101
cellular amino acid metabolic process	GO:0006520	103	0.101
wnt signaling pathway	GO:0016055	188	0.101
cellular response to nutrient levels	GO:0031669	64	0.101
negative regulation of hydrolase activity	GO:0051346	71	0.100
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.098
embryonic limb morphogenesis	GO:0030326	126	0.097	Mouse
chemotaxis	GO:0006935	247	0.097
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation	GO:2000081	1	0.094
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.094
ureteric bud morphogenesis	GO:0060675	62	0.094
renal tubule development	GO:0061326	87	0.092
ear development	GO:0043583	200	0.091	Mouse
mammary gland epithelium development	GO:0061180	65	0.090
apoptotic process involved in morphogenesis	GO:0060561	25	0.090
respiratory system development	GO:0060541	190	0.089
organ growth	GO:0035265	117	0.089	Mouse
tendon cell differentiation	GO:0035990	4	0.089
negative regulation of endopeptidase activity	GO:0010951	44	0.089
cellular response to growth factor stimulus	GO:0071363	197	0.087
mesonephric tubule morphogenesis	GO:0072171	63	0.087
locomotory behavior	GO:0007626	195	0.087
spemann organizer formation	GO:0060061	2	0.086
skeletal system morphogenesis	GO:0048705	203	0.086
appendage morphogenesis	GO:0035107	149	0.086	Mouse
regulation of cell growth	GO:0001558	91	0.085
skeletal system development	GO:0001501	356	0.085	Mouse
dendrite development	GO:0016358	115	0.085
camera type eye development	GO:0043010	266	0.084	Mouse
regulation of body fluid levels	GO:0050878	162	0.082
negative regulation of cellular protein metabolic process	GO:0032269	247	0.081
nephric duct formation	GO:0072179	4	0.080
mesonephric epithelium development	GO:0072163	94	0.080
renal inner medulla development	GO:0072053	3	0.079
carbon catabolite repression of transcription from rna polymerase ii promoter	GO:0000437	1	0.079
regulation of muscle tissue development	GO:1901861	97	0.079	Mouse
cell cell junction organization	GO:0045216	72	0.079	Mouse
gastrulation	GO:0007369	116	0.079
cell communication by electrical coupling involved in cardiac conduction	GO:0086064	2	0.079	Mouse
hypophysis morphogenesis	GO:0048850	3	0.078
regulation of homeostatic process	GO:0032844	182	0.078	Mouse
negative regulation of proteolysis	GO:0045861	74	0.078
single organism cell adhesion	GO:0098602	156	0.077
single organismal cell cell adhesion	GO:0016337	131	0.076
satellite cell activation involved in skeletal muscle regeneration	GO:0014901	3	0.076	Mouse
chondrocyte differentiation	GO:0002062	72	0.076
spemann organizer formation at the anterior end of the primitive streak	GO:0060064	1	0.076
negative regulation of nervous system development	GO:0051961	156	0.076
formation of primary germ layer	GO:0001704	77	0.076
muscle tissue development	GO:0060537	308	0.075	Mouse
renal vesicle induction	GO:0072034	3	0.075
amine metabolic process	GO:0009308	45	0.075
embryonic digit morphogenesis	GO:0042733	56	0.074	Mouse
positive regulation of epidermis development	GO:0045684	13	0.074
metanephros development	GO:0001656	79	0.073
mitotic cell cycle process	GO:1903047	159	0.073
ear morphogenesis	GO:0042471	118	0.073	Mouse
extracellular matrix organization	GO:0030198	147	0.073
regulation of response to wounding	GO:1903034	189	0.073	Mouse
regulation of epithelial cell proliferation	GO:0050678	141	0.072
digestive system development	GO:0055123	200	0.072
negative regulation of protein metabolic process	GO:0051248	282	0.072
regulation of bone remodeling	GO:0046850	28	0.072	Mouse
angiogenesis	GO:0001525	201	0.071
negative regulation of molecular function	GO:0044092	258	0.071
regulation of transmembrane transport	GO:0034762	128	0.071	Mouse
keratinization	GO:0031424	9	0.071
response to growth factor	GO:0070848	198	0.071
kidney rudiment formation	GO:0072003	3	0.070
insulin secretion	GO:0030073	89	0.070
endocrine system development	GO:0035270	98	0.070
odontogenesis of dentin containing tooth	GO:0042475	66	0.069
negative regulation of peptidase activity	GO:0010466	46	0.069
muscle contraction	GO:0006936	101	0.068
neural tube development	GO:0021915	160	0.067
glial cell differentiation	GO:0010001	131	0.067
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation	GO:2000079	1	0.067
protein maturation	GO:0051604	176	0.067
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.067
cell fate specification	GO:0001708	72	0.066
regulation of protein maturation	GO:1903317	96	0.066
neuron apoptotic process	GO:0051402	142	0.066
cardiac septum development	GO:0003279	59	0.064	Mouse
nephron morphogenesis	GO:0072028	69	0.064
pancreatic pp cell fate commitment	GO:0003329	2	0.064
renal tubule morphogenesis	GO:0061333	72	0.064
multicellular organism growth	GO:0035264	161	0.063
ameboidal type cell migration	GO:0001667	128	0.063
planar cell polarity pathway involved in ventricular septum morphogenesis	GO:0061348	2	0.063
establishment of organ orientation	GO:0048561	1	0.062
renal system development	GO:0072001	225	0.062
regulation of anagen	GO:0051884	1	0.062
developmental induction	GO:0031128	34	0.062
regulation of ion transport	GO:0043269	215	0.062	Mouse
negative regulation of cell proliferation	GO:0008285	296	0.062
regulation of secretion by cell	GO:1903530	249	0.062	Mouse
cell adhesion	GO:0007155	329	0.062
mesonephros development	GO:0001823	97	0.061
regulation of peptidase activity	GO:0052547	96	0.061
synapse organization	GO:0050808	125	0.060	Mouse
positive regulation of protein modification process	GO:0031401	299	0.060
epithelial tube formation	GO:0072175	130	0.060
embryonic heart tube development	GO:0035050	65	0.060	Mouse
lung field specification	GO:0060424	3	0.060
gonad development	GO:0008406	141	0.059
positive regulation of nervous system development	GO:0051962	221	0.059
apoptotic signaling pathway	GO:0097190	306	0.059
skeletal muscle tissue regeneration	GO:0043403	20	0.059	Mouse
negative regulation of epithelial cell proliferation	GO:0050680	64	0.059
lipid biosynthetic process	GO:0008610	179	0.059
cellular response to starvation	GO:0009267	57	0.058
odontogenesis	GO:0042476	78	0.058
paramesonephric duct development	GO:0061205	3	0.058
striated muscle tissue development	GO:0014706	293	0.057	Mouse
non canonical wnt signaling pathway via jnk cascade	GO:0038031	3	0.057
hormone secretion	GO:0046879	128	0.056
cell maturation	GO:0048469	127	0.056	Mouse
tertiary branching involved in mammary gland duct morphogenesis	GO:0060748	3	0.056
tube formation	GO:0035148	140	0.056
positive regulation of neuron differentiation	GO:0045666	141	0.056
limb morphogenesis	GO:0035108	149	0.056	Mouse
artery development	GO:0060840	53	0.055	Mouse
developmental maturation	GO:0021700	193	0.055	Mouse
labyrinthine layer development	GO:0060711	49	0.055	Mouse
hippocampus development	GO:0021766	52	0.054
male sex differentiation	GO:0046661	109	0.054
amide transport	GO:0042886	138	0.054
adult locomotory behavior	GO:0008344	91	0.053
septum primum development	GO:0003284	4	0.053	Mouse
regulation of mitotic cell cycle	GO:0007346	126	0.053
mesodermal cell differentiation	GO:0048333	22	0.053
planar cell polarity pathway involved in outflow tract morphogenesis	GO:0061347	2	0.053
female sex differentiation	GO:0046660	84	0.053
regulation of heart contraction	GO:0008016	77	0.052	Mouse
nephron tubule morphogenesis	GO:0072078	68	0.051
positive regulation of epithelial cell proliferation involved in lung morphogenesis	GO:0060501	3	0.051
regulation of hydrolase activity	GO:0051336	246	0.051
regulation of lipid metabolic process	GO:0019216	118	0.051
blastocyst development	GO:0001824	80	0.051
intermediate filament based process	GO:0045103	27	0.051
metanephric dct cell differentiation	GO:0072240	3	0.050
cell growth	GO:0016049	130	0.050
myoblast differentiation involved in skeletal muscle regeneration	GO:0014835	3	0.050
regulation of ossification	GO:0030278	112	0.050	Mouse
regulation of wound healing	GO:0061041	40	0.050	Mouse
morphogenesis of embryonic epithelium	GO:0016331	159	0.050
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	GO:0061350	2	0.049
transforming growth factor beta2 production	GO:0032906	2	0.049
lateral sprouting involved in mammary gland duct morphogenesis	GO:0060599	2	0.049
regulation of neuron differentiation	GO:0045664	281	0.049
positive regulation of cell motility	GO:2000147	116	0.048
translation	GO:0006412	93	0.048
regulation of cardiac muscle cell action potential	GO:0098901	1	0.048	Mouse
embryonic epithelial tube formation	GO:0001838	130	0.048
negative regulation of cell development	GO:0010721	169	0.048
milk ejection	GO:0060156	1	0.048	Mouse
intermediate filament organization	GO:0045109	15	0.048
regulation of osteoblast differentiation	GO:0045667	67	0.047	Mouse
extracellular structure organization	GO:0043062	148	0.047
gliogenesis	GO:0042063	141	0.047
lung morphogenesis	GO:0060425	50	0.047
multicellular organismal water homeostasis	GO:0050891	23	0.047
mesonephric duct morphogenesis	GO:0072180	4	0.046
epithelial cell maturation	GO:0002070	15	0.046	Mouse
positive regulation of cell growth	GO:0030307	33	0.046
rhythmic process	GO:0048511	174	0.046
positive regulation of mitotic cell cycle	GO:0045931	41	0.045
regulation of angiogenesis	GO:0045765	81	0.045
regulation of protein localization	GO:0032880	231	0.045	Mouse
apoptotic process involved in development	GO:1902742	28	0.045
response to steroid hormone	GO:0048545	56	0.045
regulation of morphogenesis of a branching structure	GO:0060688	53	0.045
regulation of transforming growth factor beta2 production	GO:0032909	2	0.045
mitral valve development	GO:0003174	4	0.045
cellular response to organic cyclic compound	GO:0071407	87	0.045
positive regulation of cell cycle	GO:0045787	92	0.044
regulation of cell activation	GO:0050865	289	0.044	Mouse
calcium mediated signaling	GO:0019722	46	0.044
regulation of cell motility	GO:2000145	236	0.044
intracellular protein transport	GO:0006886	204	0.044
inner ear morphogenesis	GO:0042472	101	0.044
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.043
positive regulation of nuclear division	GO:0051785	27	0.043
primary neural tube formation	GO:0014020	95	0.043
central nervous system morphogenesis	GO:0021551	2	0.043
positive regulation of osteoblast differentiation	GO:0045669	34	0.043	Mouse
negative regulation of prostatic bud formation	GO:0060686	4	0.043
detection of stimulus	GO:0051606	84	0.043	Mouse
neuron projection extension	GO:1990138	64	0.043
macromolecule catabolic process	GO:0009057	281	0.042
planar cell polarity pathway involved in pericardium morphogenesis	GO:0061354	2	0.042
planar cell polarity pathway involved in cardiac right atrium morphogenesis	GO:0061349	2	0.042
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.042
regulation of stem cell differentiation	GO:2000736	50	0.042
negative regulation of testosterone biosynthetic process	GO:2000225	1	0.042
mesonephric tubule formation	GO:0072172	11	0.042
embryonic heart tube morphogenesis	GO:0003143	51	0.042	Mouse
ventricular septum development	GO:0003281	42	0.041	Mouse
epithelial cell morphogenesis	GO:0003382	41	0.041
regulation of cell size	GO:0008361	72	0.041
negative regulation of cell cycle	GO:0045786	123	0.041
endomembrane system organization	GO:0010256	147	0.041
posttranscriptional regulation of gene expression	GO:0010608	155	0.041
cellular response to carbohydrate stimulus	GO:0071322	50	0.041
regulation of hormone levels	GO:0010817	211	0.041
regulation of establishment of protein localization	GO:0070201	181	0.041	Mouse
intestinal epithelial cell development	GO:0060576	12	0.041
tissue regeneration	GO:0042246	22	0.040	Mouse
negative regulation of neuron apoptotic process	GO:0043524	92	0.040
regulation of epidermis development	GO:0045682	33	0.040
cardiac right atrium morphogenesis	GO:0003213	3	0.040
regulation of membrane depolarization during cardiac muscle cell action potential	GO:1900825	1	0.040	Mouse
blastocyst formation	GO:0001825	33	0.040
protein localization to plasma membrane	GO:0072659	57	0.040
regulation of proteolysis	GO:0030162	164	0.039
nephron tubule formation	GO:0072079	20	0.039
determination of left right symmetry	GO:0007368	80	0.039	Mouse
positive regulation of angiogenesis	GO:0045766	46	0.039
regulation of membrane depolarization	GO:0003254	11	0.039	Mouse
digestive tract morphogenesis	GO:0048546	147	0.039
small molecule biosynthetic process	GO:0044283	132	0.039
response to organic cyclic compound	GO:0014070	198	0.039
mitotic cell cycle	GO:0000278	195	0.038
regulation of protein processing	GO:0070613	96	0.038
regulation of stem cell proliferation	GO:0072091	78	0.038
endocardial cushion to mesenchymal transition involved in heart valve formation	GO:0003199	4	0.038
lymphocyte differentiation	GO:0030098	242	0.038
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.038
ossification	GO:0001503	216	0.038	Mouse
intestinal epithelial cell differentiation	GO:0060575	14	0.038
cell communication by chemical coupling	GO:0010643	2	0.038	Mouse
positive regulation of cellular amine metabolic process	GO:0033240	5	0.037
positive regulation of branching involved in lung morphogenesis	GO:0061047	4	0.037
skeletal muscle organ development	GO:0060538	163	0.037
mesenchymal cell development	GO:0014031	93	0.037
regulation of endopeptidase activity	GO:0052548	89	0.037
determination of heart left right asymmetry	GO:0061371	48	0.037	Mouse
positive regulation of cell cell adhesion mediated by cadherin	GO:2000049	2	0.037
cellular response to extracellular stimulus	GO:0031668	81	0.037
regulation of translation	GO:0006417	71	0.037
astrocyte fate commitment	GO:0060018	4	0.037
ras protein signal transduction	GO:0007265	77	0.036
tissue remodeling	GO:0048771	102	0.036	Mouse
heart contraction	GO:0060047	93	0.036	Mouse
regulation of cell cycle	GO:0051726	281	0.036
regulation of axon extension	GO:0030516	43	0.036
development of primary sexual characteristics	GO:0045137	143	0.036
nephron tubule development	GO:0072080	84	0.036
striated muscle cell development	GO:0055002	125	0.036
somitogenesis	GO:0001756	69	0.036
regulation of cartilage development	GO:0061035	44	0.035
cellular amine metabolic process	GO:0044106	44	0.035
spinal cord development	GO:0021510	81	0.035
bmp signaling pathway	GO:0030509	93	0.035
regulation of organelle organization	GO:0033043	289	0.035
dephosphorylation	GO:0016311	129	0.035
cardiac chamber morphogenesis	GO:0003206	93	0.035	Mouse
polarity specification of proximal distal axis	GO:0010085	2	0.035
cartilage development	GO:0051216	140	0.035
cardiac neural crest cell migration involved in outflow tract morphogenesis	GO:0003253	3	0.035
branching involved in salivary gland morphogenesis	GO:0060445	26	0.035
bone development	GO:0060348	120	0.035
regulation of cell migration	GO:0030334	219	0.035
positive regulation of anagen	GO:0051885	1	0.035
metanephric loop of henle development	GO:0072236	4	0.034
sa node cell to atrial cardiac muscle cell signalling	GO:0086018	4	0.034	Mouse
ventral midline development	GO:0007418	4	0.034
respiratory tube development	GO:0030323	167	0.034
carbohydrate homeostasis	GO:0033500	128	0.034
regulation of peptide hormone secretion	GO:0090276	75	0.034
regulation of tube size	GO:0035150	57	0.034	Mouse
mesenchymal to epithelial transition	GO:0060231	12	0.034
canonical wnt signaling pathway	GO:0060070	130	0.034
regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045898	2	0.034
learning	GO:0007612	98	0.034
transdifferentiation	GO:0060290	1	0.034
myoblast differentiation	GO:0045445	52	0.033
positive regulation of cell development	GO:0010720	237	0.033
outflow tract morphogenesis	GO:0003151	53	0.033
regulation of epidermal cell differentiation	GO:0045604	21	0.033
cellular response to external stimulus	GO:0071496	88	0.033
positive regulation of hair follicle development	GO:0051798	6	0.033
pyramidal neuron migration	GO:0021852	1	0.033
fungiform papilla development	GO:0061196	6	0.033
regulation of cellular amino acid metabolic process	GO:0006521	5	0.033
tube closure	GO:0060606	91	0.033
corticotropin hormone secreting cell differentiation	GO:0060128	3	0.033
development of primary female sexual characteristics	GO:0046545	73	0.033
oviduct development	GO:0060066	3	0.033
carboxylic acid biosynthetic process	GO:0046394	86	0.032
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation	GO:0044343	1	0.032
foramen ovale closure	GO:0035922	1	0.032	Mouse
prostate gland morphogenesis	GO:0060512	32	0.032
stem cell proliferation	GO:0072089	117	0.032
peptidyl serine modification	GO:0018209	83	0.032
nephron development	GO:0072006	109	0.032
positive regulation of auditory receptor cell differentiation	GO:0045609	1	0.032
uterus morphogenesis	GO:0061038	2	0.032
regulation of defense response	GO:0031347	233	0.032
sensory system development	GO:0048880	3	0.032
cardiac septum morphogenesis	GO:0060411	46	0.032	Mouse
protein kinase b signaling	GO:0043491	74	0.031
tendon formation	GO:0035992	4	0.031
positive regulation of protein phosphorylation	GO:0001934	242	0.031
cytokine production	GO:0001816	319	0.031
response to peptide	GO:1901652	136	0.031
regulation of neuron death	GO:1901214	134	0.031
positive regulation of transforming growth factor beta2 production	GO:0032915	2	0.031
mesodermal cell fate commitment	GO:0001710	17	0.031
glandular epithelial cell differentiation	GO:0002067	38	0.031
lung epithelium development	GO:0060428	37	0.031
limbic system development	GO:0021761	72	0.030
positive regulation of cell activation	GO:0050867	158	0.030
epithelial cell proliferation involved in mammary gland duct elongation	GO:0060750	5	0.030
positive regulation of growth	GO:0045927	104	0.030
associative learning	GO:0008306	61	0.030
monosaccharide metabolic process	GO:0005996	106	0.030
regulation of cellular component size	GO:0032535	121	0.030
non canonical wnt signaling pathway via mapk cascade	GO:0038030	3	0.030
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	GO:0014834	3	0.030
gas homeostasis	GO:0033483	3	0.030
regulation of actin filament based process	GO:0032970	99	0.030	Mouse
peptide secretion	GO:0002790	114	0.030
peptide hormone secretion	GO:0030072	109	0.030
salivary gland development	GO:0007431	37	0.030
membrane organization	GO:0061024	245	0.030
metencephalon development	GO:0022037	89	0.030
peptidyl amino acid modification	GO:0018193	336	0.029
organelle fission	GO:0048285	170	0.029
regulation of neuron apoptotic process	GO:0043523	122	0.029
organ induction	GO:0001759	21	0.029
regulation of testosterone biosynthetic process	GO:2000224	2	0.029
negative regulation of neuron death	GO:1901215	98	0.029
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	GO:2000802	1	0.029
cellular response to hexose stimulus	GO:0071331	47	0.029
mesoderm formation	GO:0001707	62	0.029
cellular protein complex assembly	GO:0043623	116	0.029
planar cell polarity pathway involved in heart morphogenesis	GO:0061346	3	0.029
androgen biosynthetic process	GO:0006702	4	0.029
divalent metal ion transport	GO:0070838	172	0.029
cardiac chamber development	GO:0003205	108	0.029	Mouse
mesendoderm development	GO:0048382	3	0.029
heart morphogenesis	GO:0003007	178	0.029	Mouse
morphogenesis of a polarized epithelium	GO:0001738	37	0.029
cell junction organization	GO:0034330	77	0.029	Mouse
inflammatory response	GO:0006954	244	0.028
response to starvation	GO:0042594	65	0.028
autonomic nervous system development	GO:0048483	43	0.028
outer medullary collecting duct development	GO:0072060	1	0.028
epithelium migration	GO:0090132	63	0.028
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	GO:2000800	1	0.028
tongue development	GO:0043586	18	0.028
mammary gland morphogenesis	GO:0060443	54	0.028
non canonical wnt signaling pathway involved in heart development	GO:0061341	3	0.028
cellular homeostasis	GO:0019725	240	0.028
muscle cell development	GO:0055001	133	0.028
cardiac atrium morphogenesis	GO:0003209	23	0.027	Mouse
sclerotome development	GO:0061056	4	0.027
positive regulation of epithelial cell proliferation	GO:0050679	68	0.027
positive regulation of voltage gated calcium channel activity	GO:1901387	2	0.027
pancreatic a cell fate commitment	GO:0003326	2	0.027
ectoderm formation	GO:0001705	3	0.027
positive regulation of programmed cell death	GO:0043068	218	0.027
morphogenesis of an epithelial fold	GO:0060571	28	0.027
response to inorganic substance	GO:0010035	96	0.027
regulation of neural precursor cell proliferation	GO:2000177	70	0.027
auditory receptor cell fate determination	GO:0042668	3	0.027
t cell apoptotic process	GO:0070231	39	0.027
regulation of cell cell adhesion mediated by cadherin	GO:2000047	2	0.027
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	40	0.027
bone remodeling	GO:0046849	53	0.027	Mouse
bronchiole morphogenesis	GO:0060436	1	0.027
protein localization to organelle	GO:0033365	185	0.027
establishment or maintenance of cell polarity	GO:0007163	86	0.026
organic hydroxy compound biosynthetic process	GO:1901617	77	0.026
regulation of membrane potential	GO:0042391	192	0.026	Mouse
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.026
developmental growth involved in morphogenesis	GO:0060560	138	0.026
negative regulation of cellular component organization	GO:0051129	194	0.026
auditory receptor cell fate specification	GO:0042667	1	0.026
positive regulation of ossification	GO:0045778	47	0.026	Mouse
adult behavior	GO:0030534	135	0.026
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	GO:0072108	3	0.026
regulation of protein transport	GO:0051223	163	0.026	Mouse
positive regulation of stem cell proliferation	GO:2000648	59	0.026
negative regulation of canonical wnt signaling pathway	GO:0090090	51	0.026
regulation of intracellular transport	GO:0032386	159	0.026
axis elongation involved in somitogenesis	GO:0090245	4	0.026
visual perception	GO:0007601	52	0.026	Mouse
regulation of action potential	GO:0098900	4	0.026	Mouse
response to organonitrogen compound	GO:0010243	246	0.026
negative regulation of cell migration	GO:0030336	59	0.026
wnt signaling pathway involved in forebrain neuroblast division	GO:0021874	2	0.026
peptide transport	GO:0015833	133	0.026
negative regulation of synapse assembly	GO:0051964	3	0.025
cerebral cortex development	GO:0021987	86	0.025
neuron death	GO:0070997	154	0.025
nuclear division	GO:0000280	158	0.025
pituitary gland development	GO:0021983	38	0.025
protein ubiquitination	GO:0016567	171	0.025
diencephalon development	GO:0021536	63	0.025
sensory perception	GO:0007600	245	0.025
protein modification by small protein conjugation or removal	GO:0070647	207	0.025
cop9 signalosome assembly	GO:0010387	2	0.025
digestive tract development	GO:0048565	190	0.025
regulation of organ growth	GO:0046620	61	0.025

Gjb4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.031
	nervous system disease	DOID:863	0	0.031

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