Mus musculus

26 known processes

Tdp1

tyrosyl-DNA phosphodiesterase 1

(Aliases: AW493413,E430034L06Rik,MLZ-501,2810481F14Rik,SCAN1,4921509N21Rik,AI838772)

Tdp1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742070.136
dna metabolic processGO:00062593030.090
nuclear divisionGO:00002801580.088
ribonucleoside triphosphate catabolic processGO:00092031990.080
cellular amino acid metabolic processGO:00065201030.076
heterocycle catabolic processGO:00467002800.072
organic cyclic compound catabolic processGO:19013612950.072
regulation of cellular ketone metabolic processGO:0010565660.062
purine ribonucleoside triphosphate catabolic processGO:00092071990.056
organonitrogen compound catabolic processGO:19015652640.055
cellular nitrogen compound catabolic processGO:00442702800.052
positive regulation of cellular amine metabolic processGO:003324050.051
purine nucleotide catabolic processGO:00061952110.051
cellular ketone metabolic processGO:0042180840.051
meiotic nuclear divisionGO:00071261150.050
mitotic cell cycle processGO:19030471590.049
meiotic cell cycle processGO:1903046770.048
regulation of organelle organizationGO:00330432890.047
positive regulation of cellular amino acid metabolic processGO:004576430.047
purine containing compound metabolic processGO:00725213110.046
regulation of cellular amino acid metabolic processGO:000652150.045
microtubule based processGO:00070172360.045
purine nucleoside triphosphate metabolic processGO:00091442260.045
purine nucleoside triphosphate catabolic processGO:00091462030.045
glycosyl compound catabolic processGO:19016582060.044
nucleotide metabolic processGO:00091173320.044
macromolecule catabolic processGO:00090572810.043
purine containing compound catabolic processGO:00725232130.043
skeletal system developmentGO:00015013560.041
regulation of cellular amine metabolic processGO:0033238200.039
ras protein signal transductionGO:0007265770.038
amine metabolic processGO:0009308450.038
nucleotide catabolic processGO:00091662170.037
purine nucleoside catabolic processGO:00061522050.036
organelle assemblyGO:00709251770.036
small gtpase mediated signal transductionGO:0007264970.035
purine ribonucleotide catabolic processGO:00091542080.035
negative regulation of cell cycleGO:00457861230.035
mitotic cell cycleGO:00002781950.035
regulation of cell cycle processGO:00105641600.035
apoptotic signaling pathwayGO:00971903060.034
carbohydrate derivative catabolic processGO:19011362310.033
nucleobase containing small molecule metabolic processGO:00550863520.033
peptidyl amino acid modificationGO:00181933360.033
ribonucleotide metabolic processGO:00092592910.033
ribose phosphate metabolic processGO:00196932910.033
cellular amine metabolic processGO:0044106440.033
nucleoside phosphate metabolic processGO:00067533380.032
organelle fissionGO:00482851700.032
regulation of mitotic cell cycleGO:00073461260.030
microtubule nucleationGO:000702020.030
ribonucleoside catabolic processGO:00424542060.030
purine nucleotide metabolic processGO:00061633020.030
negative regulation of cell cycle processGO:0010948690.029
nucleocytoplasmic transportGO:00069131390.029
ribonucleoside metabolic processGO:00091192450.028
nucleoside catabolic processGO:00091642060.028
regulation of mitotic cell cycle phase transitionGO:1901990730.028
regulation of transferase activityGO:00513382630.028
cellular macromolecule catabolic processGO:00442652060.028
telomere maintenance via telomeraseGO:000700410.028
lymphocyte differentiationGO:00300982420.027
regulation of cellular catabolic processGO:00313292420.027
organophosphate catabolic processGO:00464342320.027
organism emergence from protective structureGO:007168440.027
dna replicationGO:0006260520.027
nucleoside triphosphate catabolic processGO:00091432050.027
purine ribonucleoside metabolic processGO:00461282410.027
rna dependent dna replicationGO:000627830.027
ribonucleotide catabolic processGO:00092612080.026
chromosome segregationGO:0007059480.026
nuclear transportGO:00511691390.026
meiotic cell cycleGO:00513211220.026
fertilizationGO:00095661270.026
nitrogen compound transportGO:00717052710.026
nucleoside metabolic processGO:00091162460.025
negative regulation of cellular protein metabolic processGO:00322692470.025
protein processingGO:00164851630.025
spermatogenesisGO:00072832840.025
purine ribonucleotide metabolic processGO:00091502900.025
male gamete generationGO:00482322850.025
purine ribonucleoside catabolic processGO:00461302050.025
protein modification by small protein conjugationGO:00324461870.024
regulation of ras protein signal transductionGO:00465781140.024
cellular component assembly involved in morphogenesisGO:00109271390.024
positive regulation of protein modification processGO:00314012990.023
immune effector processGO:00022523210.023
nucleic acid phosphodiester bond hydrolysisGO:0090305490.023
regulation of bindingGO:00510981110.022
leukocyte differentiationGO:00025213420.022
transmembrane transportGO:00550854120.022
negative regulation of molecular functionGO:00440922580.022
carbohydrate metabolic processGO:00059752300.022
purine ribonucleoside triphosphate metabolic processGO:00092052200.022
regulation of cell cycleGO:00517262810.022
blastocyst developmentGO:0001824800.022
aromatic compound catabolic processGO:00194392860.022
regulation of lymphocyte activationGO:00512492400.021
positive regulation of cell cycleGO:0045787920.021
organonitrogen compound biosynthetic processGO:19015661920.021
substantia nigra developmentGO:002176220.021
regulation of cell activationGO:00508652890.021
nucleoside phosphate catabolic processGO:19012922220.020
regulation of kinase activityGO:00435492490.020
protein modification by small protein conjugation or removalGO:00706472070.020
ribonucleoside monophosphate metabolic processGO:0009161800.020
cytoplasmic transportGO:00164822340.019
negative regulation of intracellular signal transductionGO:19025321670.019
nucleoside triphosphate metabolic processGO:00091412300.019
regulation of protein localizationGO:00328802310.019
ribonucleoside triphosphate metabolic processGO:00091992200.019
regionalizationGO:00030023370.019
positive regulation of organelle organizationGO:00106381280.019
synaptonemal complex organizationGO:0070193150.019
purine nucleoside metabolic processGO:00422782410.018
protein localization to nucleusGO:00345041210.018
negative regulation of dna replicationGO:000815640.018
negative regulation of protein metabolic processGO:00512482820.018
positive regulation of programmed cell deathGO:00430682180.018
hatchingGO:003518840.018
posttranscriptional regulation of gene expressionGO:00106081550.018
glycosyl compound metabolic processGO:19016572460.018
cellular homeostasisGO:00197252400.017
intracellular mrna localizationGO:000829840.017
guanosine containing compound catabolic processGO:19010691440.017
microtubule cytoskeleton organizationGO:00002261570.017
membrane organizationGO:00610242450.017
t cell activationGO:00421102890.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.017
dna repairGO:00062811070.017
negative regulation of cell proliferationGO:00082852960.017
regulation of sequence specific dna binding transcription factor activityGO:00510901060.016
rna processingGO:00063961050.016
cellular protein complex assemblyGO:00436231160.016
protein localization to organelleGO:00333651850.016
cytokine productionGO:00018163190.016
intracellular protein transportGO:00068862040.016
positive regulation of cell activationGO:00508671580.016
organelle localizationGO:00516401790.016
negative regulation of cellular component organizationGO:00511291940.015
chromatin organizationGO:00063252060.015
oxidation reduction processGO:00551143420.015
regulation of chromosome organizationGO:0033044830.015
regulation of intracellular transportGO:00323861590.015
gtp catabolic processGO:00061841430.015
negative regulation of phosphorylationGO:00423261660.015
positive regulation of protein phosphorylationGO:00019342420.015
regulation of mapk cascadeGO:00434082480.015
stem cell differentiationGO:00488632680.015
ion transmembrane transportGO:00342203610.015
response to radiationGO:00093141650.015
response to organonitrogen compoundGO:00102432460.015
guanosine containing compound metabolic processGO:19010681440.015
male meiosisGO:0007140370.014
cation transportGO:00068123990.014
protein alkylationGO:0008213810.014
regulation of protein catabolic processGO:00421761080.014
regulation of cellular response to stressGO:00801351590.014
production of molecular mediator of immune responseGO:00024401030.014
positive regulation of cellular catabolic processGO:00313311480.014
regulation of cell cycle phase transitionGO:1901987770.014
protein maturationGO:00516041760.014
endomembrane system organizationGO:00102561470.014
positive regulation of lymphocyte activationGO:00512511400.014
regulation of hydrolase activityGO:00513362460.014
trna wobble base modificationGO:000209720.014
regulation of cytokine productionGO:00018172660.014
germ cell developmentGO:00072811850.014
leukocyte mediated immunityGO:00024431740.013
cilium assemblyGO:0042384810.013
positive regulation of cell deathGO:00109422240.013
negative regulation of organelle organizationGO:0010639900.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
histone h4 k16 acetylationGO:004398430.013
anatomical structure homeostasisGO:00602491450.013
gtp metabolic processGO:00460391440.013
b cell activationGO:00421131610.013
bone developmentGO:00603481200.013
negative regulation of protein modification processGO:00314001630.013
nucleoside monophosphate metabolic processGO:0009123850.013
establishment of protein localization to organelleGO:00725941180.013
regulation of cellular protein catabolic processGO:1903362610.013
cell growthGO:00160491300.013
myeloid cell differentiationGO:00300992330.013
lymphocyte mediated immunityGO:00024491390.013
positive regulation of hydrolase activityGO:00513451480.013
regulation of microtubule cytoskeleton organizationGO:0070507370.012
cell activation involved in immune responseGO:00022631260.012
dna recombinationGO:0006310920.012
regulation of histone modificationGO:0031056560.012
methylationGO:00322591340.012
endocytosisGO:00068971680.012
regulation of cytoskeleton organizationGO:00514931220.012
homeostasis of number of cellsGO:00488722100.012
regulation of establishment of protein localizationGO:00702011810.012
skin developmentGO:00435882200.012
regulation of cell motilityGO:20001452360.012
response to organic cyclic compoundGO:00140701980.012
positive regulation of transferase activityGO:00513471670.012
cellular response to hormone stimulusGO:00328701500.012
response to light stimulusGO:00094161350.012
multicellular organismal homeostasisGO:00488711640.012
response to peptideGO:19016521360.012
cell divisionGO:00513011200.012
regulation of cell projection organizationGO:00313442060.012
regulation of protein processingGO:0070613960.012
cellular response to lipidGO:00713961450.012
development of primary sexual characteristicsGO:00451371430.012
peptidyl lysine modificationGO:0018205770.012
carbohydrate derivative biosynthetic processGO:19011371830.012
mitotic nuclear divisionGO:0007067480.012
cognitionGO:00508901490.012
learning or memoryGO:00076111480.012
cellular response to cytokine stimulusGO:00713451890.011
regulation of proteolysisGO:00301621640.011
positive regulation of immune effector processGO:00026991070.011
blood vessel morphogenesisGO:00485142850.011
stem cell maintenanceGO:00198271300.011
cell cycle g1 s phase transitionGO:0044843570.011
cilium morphogenesisGO:00602711020.011
chromosome separationGO:0051304140.011
mapk cascadeGO:00001652810.011
ossificationGO:00015032160.011
nucleotide excision repairGO:0006289130.011
cajal body organizationGO:003057610.011
protein targetingGO:00066051430.011
meiosis iGO:0007127600.011
cellular response to growth factor stimulusGO:00713631970.011
divalent inorganic cation transportGO:00725111780.011
regulation of protein kinase activityGO:00458592320.011
regulation of anatomical structure sizeGO:00900661780.011
reactive oxygen species metabolic processGO:0072593840.011
regulation of homeostatic processGO:00328441820.011
regulation of secretionGO:00510462740.011
lymphocyte activation involved in immune responseGO:0002285930.011
protein polymerizationGO:0051258570.011
inflammatory responseGO:00069542440.011
leukocyte proliferationGO:00706611720.011
purine ribonucleoside monophosphate catabolic processGO:0009169570.011
positive regulation of nucleotide catabolic processGO:0030813880.011
developmental maturationGO:00217001930.011
negative regulation of phosphorus metabolic processGO:00105631840.011
dendrite developmentGO:00163581150.010
regulation of membrane potentialGO:00423911920.010
leukocyte migrationGO:00509001240.010
covalent chromatin modificationGO:00165691630.010
regulation of purine nucleotide catabolic processGO:00331211220.010
negative regulation of mapk cascadeGO:0043409650.010
regulation of multi organism processGO:00439001110.010
telomere cappingGO:001623340.010
regulation of lymphocyte proliferationGO:00506701170.010
nuclear exportGO:0051168340.010
protein ubiquitinationGO:00165671710.010
regulation of receptor bindingGO:190012040.010
regulation of leukocyte differentiationGO:19021051590.010
metaphase plate congressionGO:005131020.010

Tdp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.050
cancerDOID:16200.050
organ system cancerDOID:005068600.033
eye and adnexa diseaseDOID:149200.028
retinal diseaseDOID:567900.028
nervous system diseaseDOID:86300.028
Human
disease of anatomical entityDOID:700.028
Human
eye diseaseDOID:561400.028
sensory system diseaseDOID:005015500.028
retinal degenerationDOID:846600.028
intestinal cancerDOID:1015500.012
gastrointestinal system cancerDOID:311900.012
large intestine cancerDOID:567200.012
retinitis pigmentosaDOID:1058400.010