Mus musculus

0 known processes

Tdp2

tyrosyl-DNA phosphodiesterase 2

(Aliases: Ttrap,D13Ertd656e)

Tdp2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.422
Human
cellular response to dna damage stimulusGO:00069742070.220
Human
cell cycle checkpointGO:0000075470.153
regulation of cell cycle processGO:00105641600.152
dna repairGO:00062811070.149
Human
organelle fissionGO:00482851700.140
cellular ketone metabolic processGO:0042180840.124
cellular nitrogen compound catabolic processGO:00442702800.112
mitotic nuclear divisionGO:0007067480.097
heterocycle catabolic processGO:00467002800.085
negative regulation of cell cycleGO:00457861230.084
male gamete generationGO:00482322850.075
regulation of mitotic cell cycleGO:00073461260.075
mitotic cell cycleGO:00002781950.074
apoptotic signaling pathwayGO:00971903060.072
mitotic chromosome condensationGO:000707610.068
macromolecule catabolic processGO:00090572810.067
negative regulation of immune system processGO:00026832090.064
regulation of organelle organizationGO:00330432890.063
dna replicationGO:0006260520.058
amp metabolic processGO:004603340.057
mitotic cell cycle processGO:19030471590.057
homeostasis of number of cellsGO:00488722100.055
regulation of cell cycleGO:00517262810.052
gonad developmentGO:00084061410.052
spermatid developmentGO:00072861080.052
chromosome segregationGO:0007059480.049
nuclear divisionGO:00002801580.048
nucleoside triphosphate metabolic processGO:00091412300.047
compound eye developmentGO:004874910.047
rna catabolic processGO:0006401290.047
negative regulation of phagocytosisGO:005076540.047
cytoplasmic transportGO:00164822340.046
meiotic nuclear divisionGO:00071261150.045
cellular amine metabolic processGO:0044106440.045
regulation of cellular ketone metabolic processGO:0010565660.045
negative regulation of cell cycle processGO:0010948690.044
meiotic cell cycle processGO:1903046770.044
ncrna 3 end processingGO:004362820.044
regulation of cellular amine metabolic processGO:0033238200.043
lateral inhibitionGO:004633110.042
cell divisionGO:00513011200.041
positive regulation of cellular amino acid metabolic processGO:004576430.041
nucleobase containing small molecule metabolic processGO:00550863520.041
translationGO:0006412930.040
spermatid differentiationGO:00485151150.039
ras protein signal transductionGO:0007265770.038
negative regulation of myeloid cell differentiationGO:0045638380.035
organic cyclic compound catabolic processGO:19013612950.035
nucleotide metabolic processGO:00091173320.034
endocytosisGO:00068971680.034
ribose phosphate metabolic processGO:00196932910.034
ribonucleoside metabolic processGO:00091192450.034
nucleoside metabolic processGO:00091162460.034
glycosyl compound metabolic processGO:19016572460.033
rna processingGO:00063961050.033
cellular macromolecule catabolic processGO:00442652060.032
mrna processingGO:0006397630.032
negative regulation of cellular component organizationGO:00511291940.032
response to organic cyclic compoundGO:00140701980.032
amp biosynthetic processGO:000616720.032
protein localization to organelleGO:00333651850.032
dna replication checkpointGO:000007620.031
purine ribonucleoside monophosphate metabolic processGO:0009167800.031
dna packagingGO:0006323300.031
ribonucleoside monophosphate metabolic processGO:0009161800.031
cellular homeostasisGO:00197252400.031
leukocyte differentiationGO:00025213420.031
regulation of cellular amino acid metabolic processGO:000652150.030
blastocyst developmentGO:0001824800.030
ribonucleotide metabolic processGO:00092592910.030
dna conformation changeGO:0071103370.029
microtubule cytoskeleton organizationGO:00002261570.029
cellular amino acid metabolic processGO:00065201030.029
nucleoside phosphate metabolic processGO:00067533380.029
aromatic compound catabolic processGO:00194392860.029
germ cell developmentGO:00072811850.029
b cell activationGO:00421131610.029
chemotaxisGO:00069352470.028
cellular transition metal ion homeostasisGO:0046916320.028
regulation of translationGO:0006417710.027
myeloid cell differentiationGO:00300992330.027
regulation of cell activationGO:00508652890.026
regulation of cell cycle phase transitionGO:1901987770.026
respiratory tube developmentGO:00303231670.026
nucleoside catabolic processGO:00091642060.026
negative regulation of cell activationGO:00508661110.026
ribonucleoside triphosphate metabolic processGO:00091992200.026
posttranscriptional regulation of gene expressionGO:00106081550.025
carbohydrate derivative biosynthetic processGO:19011371830.025
rna splicingGO:0008380540.025
organonitrogen compound biosynthetic processGO:19015661920.024
regulation of nuclear divisionGO:0051783560.024
positive regulation of protein modification processGO:00314012990.024
multicellular organism growthGO:00352641610.023
monosaccharide metabolic processGO:00059961060.023
meiosis iGO:0007127600.023
respiratory system developmentGO:00605411900.022
dna integrity checkpointGO:0031570280.022
protein modification by small protein conjugation or removalGO:00706472070.021
negative regulation of cell cycle phase transitionGO:1901988480.021
sister chromatid segregationGO:0000819200.021
stem cell developmentGO:00488642190.021
positive regulation of glycogen catabolic processGO:004581920.021
mrna catabolic processGO:0006402220.020
nucleoside phosphate catabolic processGO:19012922220.020
axonogenesisGO:00074092740.020
hematopoietic progenitor cell differentiationGO:00022441430.020
negative regulation of lymphocyte activationGO:0051250910.019
intra s dna damage checkpointGO:003157340.019
negative regulation of dna replicationGO:000815640.019
cellular ion homeostasisGO:00068731650.019
negative regulation of apoptotic signaling pathwayGO:20012341040.018
adult behaviorGO:00305341350.018
regulation of cellular component biogenesisGO:00440871810.018
organophosphate catabolic processGO:00464342320.018
cellular metal ion homeostasisGO:00068751510.018
stem cell maintenanceGO:00198271300.018
inflammatory responseGO:00069542440.018
rna 3 end processingGO:0031123200.017
anatomical structure homeostasisGO:00602491450.017
purine nucleoside metabolic processGO:00422782410.017
regulation of mitotic cell cycle phase transitionGO:1901990730.017
nitrogen compound transportGO:00717052710.017
small gtpase mediated signal transductionGO:0007264970.017
snrna processingGO:001618010.017
glycosyl compound catabolic processGO:19016582060.017
peptidyl amino acid modificationGO:00181933360.017
carbohydrate derivative catabolic processGO:19011362310.017
lung developmentGO:00303241640.016
cellular protein catabolic processGO:00442571550.016
nucleic acid phosphodiester bond hydrolysisGO:0090305490.016
purine ribonucleoside metabolic processGO:00461282410.016
regionalizationGO:00030023370.016
protein autophosphorylationGO:0046777610.016
amine metabolic processGO:0009308450.016
b cell differentiationGO:0030183780.016
regulation of ras protein signal transductionGO:00465781140.016
negative regulation of growthGO:0045926990.016
purine ribonucleotide catabolic processGO:00091542080.015
determination of adult lifespanGO:0008340110.015
development of primary sexual characteristicsGO:00451371430.015
intrinsic apoptotic signaling pathwayGO:00971931320.015
stem cell differentiationGO:00488632680.015
mrna splicing via spliceosomeGO:0000398430.015
regulation of response to dna damage stimulusGO:2001020340.015
regulation of chromosome organizationGO:0033044830.014
regulation of cellular response to stressGO:00801351590.014
lymphocyte differentiationGO:00300982420.014
ion transmembrane transportGO:00342203610.014
protein maturationGO:00516041760.014
purine nucleotide metabolic processGO:00061633020.014
regulation of lymphocyte activationGO:00512492400.014
myeloid leukocyte differentiationGO:00025731190.014
negative regulation of molecular functionGO:00440922580.014
defense response to other organismGO:00985421970.014
positive regulation of hydrolase activityGO:00513451480.014
cellular chemical homeostasisGO:00550822150.014
axon guidanceGO:00074111410.014
microtubule based processGO:00070172360.014
transmembrane transportGO:00550854120.014
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.013
atp metabolic processGO:0046034750.013
cardiac muscle cell contractionGO:008600370.013
negative regulation of b cell differentiationGO:004557840.013
cellular protein complex assemblyGO:00436231160.013
dna dependent dna replicationGO:0006261240.013
regulation of chromatin silencingGO:003193520.013
negative regulation of protein metabolic processGO:00512482820.013
purine ribonucleotide metabolic processGO:00091502900.013
meiotic cell cycleGO:00513211220.013
regulation of dna endoreduplicationGO:003287530.013
regulation of cellular catabolic processGO:00313292420.013
regulation of carbohydrate metabolic processGO:0006109750.013
intracellular protein transportGO:00068862040.013
purine ribonucleoside catabolic processGO:00461302050.013
ribonucleoside catabolic processGO:00424542060.013
positive regulation of cellular amine metabolic processGO:003324050.013
regulation of synaptic growth at neuromuscular junctionGO:000858240.012
purine nucleoside triphosphate catabolic processGO:00091462030.012
mrna metabolic processGO:0016071840.012
nucleoside monophosphate metabolic processGO:0009123850.012
adult locomotory behaviorGO:0008344910.012
skeletal system developmentGO:00015013560.012
organophosphate biosynthetic processGO:00904071220.012
purine nucleoside monophosphate metabolic processGO:0009126810.012
purine containing compound metabolic processGO:00725213110.012
placenta developmentGO:00018901400.012
protein targetingGO:00066051430.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
muscle system processGO:00030121410.011
positive regulation of innate immune responseGO:0045089800.011
rna interferenceGO:001624620.011
protein modification by small protein conjugationGO:00324461870.011
response to oxidative stressGO:00069791230.011
negative regulation of cellular protein metabolic processGO:00322692470.011
learning or memoryGO:00076111480.011
base excision repairGO:000628490.011
positive regulation of carbohydrate metabolic processGO:0045913300.011
regulation of histone methylationGO:0031060300.011
mitochondrion organizationGO:00070051340.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
meiotic chromosome segregationGO:0045132190.011
regulation of vesicle mediated transportGO:00606271390.011
dna damage checkpointGO:0000077260.011
negative regulation of leukocyte differentiationGO:1902106510.011
g2 dna damage checkpointGO:003157280.011
gland developmentGO:00487323300.011
cognitionGO:00508901490.010
organelle assemblyGO:00709251770.010
positive regulation of protein phosphorylationGO:00019342420.010
protein acylationGO:0043543640.010
cell type specific apoptotic processGO:00972852680.010
regulation of cell divisionGO:0051302760.010
memoryGO:0007613580.010
maternal determination of anterior posterior axis embryoGO:000835820.010
regulation of b cell activationGO:0050864810.010
developmental maturationGO:00217001930.010
cellular carbohydrate metabolic processGO:00442621190.010

Tdp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.066
disease of anatomical entityDOID:700.066
central nervous system diseaseDOID:33100.043
neurodegenerative diseaseDOID:128900.032
musculoskeletal system diseaseDOID:1700.016
muscle tissue diseaseDOID:6600.013
myopathyDOID:42300.013
muscular diseaseDOID:008000000.013
motor neuron diseaseDOID:23100.012
amyotrophic lateral sclerosisDOID:33200.012