Mus musculus

153 known processes

Pik3ca

phosphatidylinositol 3-kinase, catalytic, alpha polypeptide

(Aliases: p110,p110alpha,MGC161268,6330412C24Rik,caPI3K)

Pik3ca biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lipid phosphorylationGO:0046834251.000
phosphatidylinositol 3 phosphate biosynthetic processGO:003609261.000
phosphatidylinositol phosphorylationGO:0046854231.000
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.992
cell substrate adhesionGO:00315891300.988
Mouse
cellular response to nutrient levelsGO:0031669640.983
regulation of synaptic plasticityGO:0048167870.981
cell matrix adhesionGO:0007160680.980
Mouse
homeostasis of number of cellsGO:00488722100.969
Mouse
cell type specific apoptotic processGO:00972852680.968
glycerolipid biosynthetic processGO:0045017500.966
cellular response to starvationGO:0009267570.965
cellular ketone metabolic processGO:0042180840.961
regulation of cellular response to stressGO:00801351590.951
exocytosisGO:00068871210.935
intrinsic apoptotic signaling pathwayGO:00971931320.931
regulation of neuronal synaptic plasticityGO:0048168300.930
dna metabolic processGO:00062593030.930
dna alkylationGO:0006305430.928
response to light stimulusGO:00094161350.926
regulation of cell sizeGO:0008361720.924
regulation of cell motilityGO:20001452360.923
response to peptide hormoneGO:00434341270.922
autophagyGO:0006914450.911
apoptotic signaling pathwayGO:00971903060.910
associative learningGO:0008306610.901
glycerolipid metabolic processGO:00464861220.901
regulation of cell migrationGO:00303342190.901
regulation of cellular component sizeGO:00325351210.900
lymphocyte homeostasisGO:0002260640.898
Mouse
regulation of autophagyGO:0010506300.896
peptidyl serine modificationGO:0018209830.894
synaptic transmissionGO:00072683290.889
regulation of transferase activityGO:00513382630.884
regulation of mapk cascadeGO:00434082480.882
response to starvationGO:0042594650.876
regulation of kinase activityGO:00435492490.875
stem cell differentiationGO:00488632680.869
regulation of cellular ketone metabolic processGO:0010565660.869
myeloid cell differentiationGO:00300992330.865
amine metabolic processGO:0009308450.864
cellular response to organonitrogen compoundGO:00714171450.863
intracellular protein transportGO:00068862040.858
leukocyte differentiationGO:00025213420.855
dna modificationGO:0006304500.849
t cell differentiationGO:00302171740.847
cellular response to insulin stimulusGO:0032869780.846
organophosphate biosynthetic processGO:00904071220.838
establishment of protein localization to organelleGO:00725941180.837
purine ribonucleotide metabolic processGO:00091502900.835
regulation of hydrolase activityGO:00513362460.834
leukocyte homeostasisGO:0001776790.831
Mouse
response to radiationGO:00093141650.829
macroautophagyGO:0016236210.829
digestive tract morphogenesisGO:00485461470.825
negative regulation of immune system processGO:00026832090.824
positive regulation of cellular amino acid metabolic processGO:004576430.823
regulation of cellular catabolic processGO:00313292420.823
regulation of peptidyl serine phosphorylationGO:0033135390.821
positive regulation of cell motilityGO:20001471160.820
regulation of ras protein signal transductionGO:00465781140.818
guanosine containing compound metabolic processGO:19010681440.813
mitotic cell cycleGO:00002781950.812
regulation of cellular amino acid metabolic processGO:000652150.811
cellular response to peptideGO:1901653920.806
nucleoside triphosphate catabolic processGO:00091432050.803
neuron apoptotic processGO:00514021420.796
protein autophosphorylationGO:0046777610.790
dna methylationGO:0006306430.789
female gamete generationGO:0007292740.788
chemotaxisGO:00069352470.787
Worm
purine nucleoside metabolic processGO:00422782410.783
response to nutrient levelsGO:00316671090.783
endocytosisGO:00068971680.780
guanosine containing compound catabolic processGO:19010691440.778
extrinsic apoptotic signaling pathwayGO:00971911260.777
lymphocyte differentiationGO:00300982420.776
response to extracellular stimulusGO:00099911270.766
negative regulation of cell proliferationGO:00082852960.765
gastrulationGO:00073691160.762
small gtpase mediated signal transductionGO:0007264970.758
regulation of cell substrate adhesionGO:0010810730.758
Mouse
negative regulation of leukocyte differentiationGO:1902106510.758
digestive tract developmentGO:00485651900.757
cellular response to radiationGO:0071478280.756
protein kinase b signalingGO:0043491740.754
peptidyl serine phosphorylationGO:0018105740.753
cellular response to external stimulusGO:0071496880.753
nucleoside phosphate biosynthetic processGO:1901293790.750
cellular response to dna damage stimulusGO:00069742070.742
regulation of cellular amine metabolic processGO:0033238200.742
regulation of long term neuronal synaptic plasticityGO:0048169190.739
regulation of leukocyte differentiationGO:19021051590.732
positive regulation of cellular catabolic processGO:00313311480.730
heterocycle catabolic processGO:00467002800.730
blood vessel morphogenesisGO:00485142850.726
nfat protein import into nucleusGO:005153160.724
developmental maturationGO:00217001930.722
macromolecule methylationGO:00434141200.712
macromolecule catabolic processGO:00090572810.709
cellular response to extracellular stimulusGO:0031668810.707
protein targetingGO:00066051430.706
response to growth factorGO:00708481980.704
regulation of ras gtpase activityGO:0032318880.698
regulation of secretionGO:00510462740.696
protein localization to organelleGO:00333651850.694
myeloid leukocyte differentiationGO:00025731190.694
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.685
lung developmentGO:00303241640.683
posttranscriptional regulation of gene expressionGO:00106081550.679
negative regulation of neuron deathGO:1901215980.677
regulation of myeloid leukocyte differentiationGO:0002761580.676
positive regulation of rac protein signal transductionGO:003502210.670
peptidyl amino acid modificationGO:00181933360.669
oogenesisGO:0048477560.667
glycerophospholipid biosynthetic processGO:0046474320.667
multicellular organism growthGO:00352641610.665
positive regulation of ras gtpase activityGO:0032320650.662
mapk cascadeGO:00001652810.658
positive regulation of mapk cascadeGO:00434101700.656
dendrite developmentGO:00163581150.653
positive regulation of transcription by galactoseGO:000041110.644
nucleotide catabolic processGO:00091662170.639
regulation of myeloid cell differentiationGO:0045637960.636
purine ribonucleoside triphosphate catabolic processGO:00092071990.635
nucleobase containing small molecule metabolic processGO:00550863520.632
glycosyl compound metabolic processGO:19016572460.631
insulin receptor signaling pathwayGO:0008286490.625
positive regulation of transferase activityGO:00513471670.624
ribonucleotide metabolic processGO:00092592910.624
cellular amino acid metabolic processGO:00065201030.618
purine nucleotide metabolic processGO:00061633020.616
cellular response to lipidGO:00713961450.616
positive regulation of cellular amine metabolic processGO:003324050.610
response to organonitrogen compoundGO:00102432460.607
respiratory tube developmentGO:00303231670.605
cellular response to peptide hormone stimulusGO:0071375920.604
organic cyclic compound catabolic processGO:19013612950.601
regulation of apoptotic signaling pathwayGO:20012331970.601
appendage developmentGO:00487361660.601
regulation of secretion by cellGO:19035302490.599
phospholipid biosynthetic processGO:0008654360.599
cellular lipid metabolic processGO:00442553230.598
positive regulation of cell migrationGO:00303351090.597
striated muscle tissue developmentGO:00147062930.597
cognitionGO:00508901490.589
Worm
germ cell developmentGO:00072811850.584
digestive system developmentGO:00551232000.584
glycerophospholipid metabolic processGO:0006650710.580
wnt signaling pathwayGO:00160551880.579
ribonucleoside catabolic processGO:00424542060.576
stem cell developmentGO:00488642190.574
response to insulinGO:00328681000.571
cytokine productionGO:00018163190.570
purine ribonucleoside metabolic processGO:00461282410.561
regulation of nucleoside metabolic processGO:00091181300.549
cellular macromolecule catabolic processGO:00442652060.548
ras protein signal transductionGO:0007265770.537
cellular protein catabolic processGO:00442571550.528
organelle assemblyGO:00709251770.523
protein localization to nucleusGO:00345041210.511
regionalizationGO:00030023370.510
phagocytosisGO:0006909660.507
learning or memoryGO:00076111480.504
Worm
regulation of protein kinase activityGO:00458592320.504
methylationGO:00322591340.501
t cell activationGO:00421102890.499
positive regulation of protein phosphorylationGO:00019342420.498
ribonucleotide catabolic processGO:00092612080.497
neuron projection guidanceGO:00974851410.497
negative regulation of myeloid leukocyte differentiationGO:0002762200.496
regulation of metal ion transportGO:00109591060.495
Mouse
regulation of protein transportGO:00512231630.494
positive regulation of jnk cascadeGO:0046330460.493
cellular response to light stimulusGO:0071482190.491
negative regulation of fibroblast apoptotic processGO:200027060.487
olfactory learningGO:000835520.483
adaptive immune responseGO:00022501550.482
purine nucleoside triphosphate catabolic processGO:00091462030.477
stem cell maintenanceGO:00198271300.475
b cell activationGO:00421131610.474
Mouse
regulation of protein localizationGO:00328802310.472
cellular nitrogen compound catabolic processGO:00442702800.470
tumor necrosis factor superfamily cytokine productionGO:0071706510.469
second messenger mediated signalingGO:0019932730.468
rac protein signal transductionGO:0016601130.468
positive regulation of protein modification processGO:00314012990.467
ribose phosphate metabolic processGO:00196932910.465
nuclear transportGO:00511691390.465
cell maturationGO:00484691270.465
positive regulation of protein kinase activityGO:00458601440.463
myeloid cell homeostasisGO:00022621140.461
cyclic nucleotide metabolic processGO:0009187590.461
nucleotide metabolic processGO:00091173320.461
regulation of organ growthGO:0046620610.459
gtp catabolic processGO:00061841430.455
purine ribonucleotide catabolic processGO:00091542080.454
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.450
epithelial cell developmentGO:00020641590.447
calcium ion homeostasisGO:00550741270.447
Mouse
nucleoside phosphate metabolic processGO:00067533380.446
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.442
b cell differentiationGO:0030183780.440
nucleoside catabolic processGO:00091642060.435
ribonucleoside metabolic processGO:00091192450.433
protein modification by small protein conjugation or removalGO:00706472070.433
oocyte axis specificationGO:000730920.432
regulation of system processGO:00440572000.432
regulation of mitotic cell cycleGO:00073461260.431
aromatic compound catabolic processGO:00194392860.429
axon guidanceGO:00074111410.427
single organism nuclear importGO:1902593950.427
respiratory system developmentGO:00605411900.423
regulation of neuron apoptotic processGO:00435231220.422
embryonic skeletal system developmentGO:00487061200.421
learningGO:0007612980.415
muscle cell differentiationGO:00426922610.414
purine nucleotide catabolic processGO:00061952110.409
osteoclast differentiationGO:0030316620.408
purine ribonucleoside triphosphate metabolic processGO:00092052200.407
cellular response to abiotic stimulusGO:0071214560.403
cellular amine metabolic processGO:0044106440.402
skeletal muscle organ developmentGO:00605381630.401
epithelial tube morphogenesisGO:00605623030.399
metal ion homeostasisGO:00550651890.398
Mouse
regulation of proteolysisGO:00301621640.395
positive regulation of erk1 and erk2 cascadeGO:0070374470.390
response to metal ionGO:0010038470.386
Worm
cell adhesionGO:00071553290.385
Mouse
genetic imprintingGO:0071514270.384
proteolysis involved in cellular protein catabolic processGO:00516031470.380
embryonic hemopoiesisGO:0035162230.371
response to peptideGO:19016521360.370
purine nucleoside catabolic processGO:00061522050.369
organonitrogen compound catabolic processGO:19015652640.369
positive regulation of apoptotic processGO:00430652170.367
regulation of erk1 and erk2 cascadeGO:0070372710.364
reactive oxygen species metabolic processGO:0072593840.360
visual learningGO:0008542440.360
positive regulation of peptidyl serine phosphorylationGO:0033138250.359
cellular response to hormone stimulusGO:00328701500.359
skeletal system developmentGO:00015013560.359
regulation of cell cycleGO:00517262810.358
sensory organ morphogenesisGO:00905962420.357
cytoplasmic transportGO:00164822340.356
regulation of lipid metabolic processGO:00192161180.356
positive regulation of intracellular transportGO:0032388700.354
positive regulation of cell deathGO:00109422240.352
cellular ion homeostasisGO:00068731650.352
Mouse
ion transmembrane transportGO:00342203610.351
Mouse
cellular response to growth factor stimulusGO:00713631970.351
glycosyl compound catabolic processGO:19016582060.349
positive regulation of cytokine productionGO:00018191740.349
establishment of vesicle localizationGO:0051650810.347
b cell homeostasisGO:0001782340.347
Mouse
cellular response to acid chemicalGO:0071229680.346
neurotransmitter secretionGO:0007269620.345
establishment of organelle localizationGO:00516561220.343
activation of adenylate cyclase activityGO:000719040.343
body morphogenesisGO:0010171450.342
positive regulation of programmed cell deathGO:00430682180.342
regulation of protein stabilityGO:0031647520.339
purine nucleoside triphosphate metabolic processGO:00091442260.337
regulation of membrane potentialGO:00423911920.337
purine containing compound metabolic processGO:00725213110.335
negative regulation of cell cycleGO:00457861230.335
response to transforming growth factor betaGO:0071559880.331
hyperosmotic responseGO:000697240.330
regulation of establishment of protein localizationGO:00702011810.329
regulation of purine nucleotide metabolic processGO:19005421690.328
ribose phosphate biosynthetic processGO:0046390590.328
negative regulation of protein modification processGO:00314001630.326
positive regulation of growthGO:00459271040.326
positive regulation of apoptotic signaling pathwayGO:2001235950.325
regulation of organelle organizationGO:00330432890.324
microtubule based processGO:00070172360.322
oocyte differentiationGO:0009994350.322
regulation of ion transportGO:00432692150.321
Mouse
neuron deathGO:00709971540.320
skeletal system morphogenesisGO:00487052030.320
cellular response to organic cyclic compoundGO:0071407870.318
muscle tissue developmentGO:00605373080.314
metencephalon developmentGO:0022037890.311
nucleocytoplasmic transportGO:00069131390.309
cellular metal ion homeostasisGO:00068751510.307
Mouse
monosaccharide metabolic processGO:00059961060.306
organophosphate catabolic processGO:00464342320.306
response to uvGO:0009411440.305
purine containing compound catabolic processGO:00725232130.305
columnar cuboidal epithelial cell differentiationGO:0002065820.304
muscle adaptationGO:0043500390.303
gland developmentGO:00487323300.297
cellular homeostasisGO:00197252400.297
Mouse
actin cytoskeleton organizationGO:00300362200.289
nuclear importGO:0051170950.288
axonogenesisGO:00074092740.282
connective tissue developmentGO:00614481790.282
positive regulation of proteolysisGO:0045862850.281
cyclic nucleotide biosynthetic processGO:0009190440.279
translationGO:0006412930.279
carbon catabolite activation of transcriptionGO:004599140.275
mitotic cell cycle processGO:19030471590.275
positive regulation of organelle organizationGO:00106381280.275
response to inorganic substanceGO:0010035960.273
Worm
regulation of cell adhesionGO:00301551540.268
Mouse
regulation of cell growth involved in cardiac muscle cell developmentGO:006105030.267
protein catabolic processGO:00301632210.266
ameboidal type cell migrationGO:00016671280.266
regulation of exocytosisGO:0017157610.264
regulation of vesicle mediated transportGO:00606271390.263
leukocyte activation involved in immune responseGO:00023661260.258
negative regulation of zinc ion transmembrane transportGO:007158320.257
Mouse
ubiquitin dependent protein catabolic processGO:00065111290.255
organ growthGO:00352651170.254
maintenance of locationGO:0051235890.252
g protein coupled receptor signaling pathwayGO:00071862430.250
cell divisionGO:00513011200.250
Mouse
jnk cascadeGO:0007254720.250
ribonucleoside triphosphate metabolic processGO:00091992200.248
regulation of jnk cascadeGO:0046328620.248
lipid biosynthetic processGO:00086101790.248
adherens junction organizationGO:0034332280.242
regulation of neuron deathGO:19012141340.240
epidermal growth factor receptor signaling pathwayGO:0007173280.239
regulation of muscle tissue developmentGO:1901861970.238
embryonic organ morphogenesisGO:00485622760.238
spermatogenesisGO:00072832840.235
positive regulation of ras protein signal transductionGO:0046579130.235
camp metabolic processGO:0046058400.235
modification dependent protein catabolic processGO:00199411330.235
carbohydrate derivative biosynthetic processGO:19011371830.234
visual behaviorGO:0007632450.233
gonad developmentGO:00084061410.232
epithelial cell proliferationGO:00506731740.231
cation homeostasisGO:00550802120.230
Mouse
nucleoside phosphate catabolic processGO:19012922220.229
nitrogen compound transportGO:00717052710.228
cerebellum developmentGO:0021549770.227
regulation of translationGO:0006417710.225
cell cell junction organizationGO:0045216720.224
immune effector processGO:00022523210.223
microtubule cytoskeleton organizationGO:00002261570.221
carbon catabolite regulation of transcriptionGO:004599040.221
generation of precursor metabolites and energyGO:00060911030.218
camp biosynthetic processGO:0006171310.217
negative regulation of cellular catabolic processGO:0031330470.216
regulation of rac protein signal transductionGO:0035020190.215
response to alcoholGO:0097305480.215
erk1 and erk2 cascadeGO:0070371770.215
regulation of cytokine productionGO:00018172660.215
regulation of actin filament based processGO:0032970990.214
development of primary sexual characteristicsGO:00451371430.214
divalent inorganic cation homeostasisGO:00725071380.213
Mouse
nucleoside triphosphate metabolic processGO:00091412300.213
negative regulation of myeloid cell differentiationGO:0045638380.213
circadian rhythmGO:00076231140.212
negative regulation of apoptotic signaling pathwayGO:20012341040.211
negative regulation of protein metabolic processGO:00512482820.211
leukocyte mediated immunityGO:00024431740.210
stress activated protein kinase signaling cascadeGO:0031098810.208
regulation of chemotaxisGO:0050920530.208
Worm
purine ribonucleoside catabolic processGO:00461302050.205
regulation of lipid kinase activityGO:0043550140.205
establishment or maintenance of cell polarityGO:0007163860.200
negative regulation of phosphorylationGO:00423261660.200
cell chemotaxisGO:0060326810.196
cation transportGO:00068123990.196
Mouse
actin filament bundle assemblyGO:0051017400.195
striated muscle cell developmentGO:00550021250.195
regulation of nucleotide metabolic processGO:00061401690.195
inorganic ion transmembrane transportGO:00986602340.195
Mouse
cell fate commitmentGO:00451652100.194
carbohydrate metabolic processGO:00059752300.194
regulation of cytoskeleton organizationGO:00514931220.193
regulation of gtp catabolic processGO:00331241130.193
positive regulation of protein transportGO:0051222930.192
regulation of reactive oxygen species metabolic processGO:2000377400.191
mitotic sister chromatid cohesionGO:000706410.190
regulation of cytoplasmic transportGO:19036491120.190
ribonucleoside triphosphate catabolic processGO:00092031990.189
negative regulation of mitotic cell cycleGO:0045930580.188
regulation of camp metabolic processGO:0030814300.187
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108140.185
regulation of cell activationGO:00508652890.184
limb developmentGO:00601731660.184
positive regulation of kinase activityGO:00336741550.183
carbohydrate derivative catabolic processGO:19011362310.182
regulation of phosphatidylinositol 3 kinase activityGO:0043551140.181
positive regulation of cellular protein catabolic processGO:1903364340.181
regulation of cellular protein catabolic processGO:1903362610.180
male sex differentiationGO:00466611090.178
cd4 positive alpha beta t cell activationGO:0035710450.178
ventricular cardiac myofibril assemblyGO:005500530.178
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.178
lipid modificationGO:0030258650.176
protein import into nucleusGO:0006606950.174
protein modification by small protein conjugationGO:00324461870.172
regulation of purine nucleotide catabolic processGO:00331211220.169
transition metal ion transportGO:0000041380.168
Mouse
leukocyte migrationGO:00509001240.167
positive regulation of defense responseGO:00313491240.167
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.166
genitalia developmentGO:0048806370.165
protein acylationGO:0043543640.164
alpha beta t cell differentiationGO:0046632690.164
erythrocyte differentiationGO:0030218880.162
negative regulation of neuron apoptotic processGO:0043524920.161
cellular response to biotic stimulusGO:0071216920.160
embryonic limb morphogenesisGO:00303261260.160
regulation of protein targetingGO:1903533610.159
regulation of synapse structural plasticityGO:005182340.157
regulation of innate immune responseGO:0045088910.156
negative regulation of intracellular signal transductionGO:19025321670.155
cellular carbohydrate metabolic processGO:00442621190.151
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.151
negative regulation of organ growthGO:0046621170.150
i kappab kinase nf kappab signalingGO:0007249850.150
cellular divalent inorganic cation homeostasisGO:00725031270.149
Mouse
protein ubiquitinationGO:00165671710.149
regulation of purine nucleotide biosynthetic processGO:1900371340.148
male gamete generationGO:00482322850.145
regulation of intracellular protein transportGO:0033157820.144
nucleotide biosynthetic processGO:0009165780.143
nucleoside monophosphate metabolic processGO:0009123850.142
response to amphetamineGO:0001975160.142
cyclic purine nucleotide metabolic processGO:0052652430.141
positive regulation of stress activated mapk cascadeGO:0032874480.140
protein importGO:00170381010.140
erbb signaling pathwayGO:0038127320.140
response to drugGO:0042493750.139
oocyte constructionGO:000730820.139
lymphocyte proliferationGO:00466511640.137
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.137
regulation of nucleotide catabolic processGO:00308111220.135
hematopoietic progenitor cell differentiationGO:00022441430.134
purine nucleotide biosynthetic processGO:0006164650.134
regulation of anatomical structure sizeGO:00900661780.134
regulation of cell cycle phase transitionGO:1901987770.133
leukocyte apoptotic processGO:0071887710.133
cell growthGO:00160491300.133
positive regulation of mitotic sister chromatid separationGO:190197020.132
formation of primary germ layerGO:0001704770.131
phosphatidylinositol mediated signalingGO:0048015410.130
regulation of mitotic cell cycle phase transitionGO:1901990730.130
regulation of intracellular transportGO:00323861590.130
tor signalingGO:0031929210.129
regulation of osteoclast differentiationGO:0045670360.128
positive regulation of autophagyGO:001050890.128
negative regulation of transmembrane transportGO:0034763150.127
Mouse
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.126
positive regulation of lyase activityGO:0051349110.126
mesenchyme morphogenesisGO:0072132320.126
regulation of ion transmembrane transportGO:00347651190.126
Mouse
cellular chemical homeostasisGO:00550822150.125
Mouse
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.125
negative regulation of autophagyGO:001050790.125
regulation of protein catabolic processGO:00421761080.125
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.124
thymus developmentGO:0048538410.123
inositol lipid mediated signalingGO:0048017410.123
cell fate determinationGO:0001709320.122
divalent inorganic cation transportGO:00725111780.121
regulation of cellular response to growth factor stimulusGO:0090287820.121
modification dependent macromolecule catabolic processGO:00436321330.120
regulation of jak stat cascadeGO:0046425340.120
neural tube developmentGO:00219151600.120
regulation of erbb signaling pathwayGO:1901184160.120
lymphocyte apoptotic processGO:0070227540.119
organonitrogen compound biosynthetic processGO:19015661920.119
muscle contractionGO:00069361010.118
transforming growth factor beta receptor signaling pathwayGO:0007179710.118
regulation of canonical wnt signaling pathwayGO:0060828820.117
nucleoside metabolic processGO:00091162460.117
negative regulation of homeostatic processGO:0032845710.116
protein processingGO:00164851630.116
regulation of lymphocyte differentiationGO:00456191070.116
regulation of protein serine threonine kinase activityGO:00719001570.115
regulation of homeostatic processGO:00328441820.114
detection of mechanical stimulusGO:0050982270.114
myeloid leukocyte activationGO:0002274830.113
calcium mediated signalingGO:0019722460.113
negative regulation of ras protein signal transductionGO:0046580180.113
regulation of peptidyl tyrosine phosphorylationGO:0050730930.112
positive regulation of leukocyte differentiationGO:1902107860.112
regulation of macroautophagyGO:0016241120.111
organelle localizationGO:00516401790.111

Pik3ca disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.994
Human
cancerDOID:16200.978
Human
organ system cancerDOID:005068600.936
Human
large intestine cancerDOID:567200.601
Human
colon cancerDOID:21900.601
Human
gastrointestinal system cancerDOID:311900.601
Human
intestinal cancerDOID:1015500.601
Human
colorectal cancerDOID:925600.601
Human
endocrine gland cancerDOID:17000.291