Mus musculus

65 known processes

Naglu

alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)

Naglu biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lysosome organizationGO:0007040210.259
lytic vacuole organizationGO:0080171210.157
vacuole organizationGO:0007033380.128
sphingolipid metabolic processGO:0006665450.111
sphingolipid catabolic processGO:003014970.105
carbohydrate metabolic processGO:00059752300.100
carbohydrate derivative catabolic processGO:19011362310.100
oxidation reduction processGO:00551143420.077
cellular lipid metabolic processGO:00442553230.059
ceramide metabolic processGO:0006672310.059
membrane lipid metabolic processGO:0006643530.057
organonitrogen compound catabolic processGO:19015652640.056
glycolipid metabolic processGO:0006664250.056
locomotory behaviorGO:00076261950.053
male gamete generationGO:00482322850.045
lymphocyte mediated immunityGO:00024491390.044
sensory perceptionGO:00076002450.044
skeletal system developmentGO:00015013560.044
cellular amide metabolic processGO:0043603580.043
small molecule biosynthetic processGO:00442831320.043
membrane lipid biosynthetic processGO:0046467320.042
spermatogenesisGO:00072832840.039
neuromuscular processGO:0050905990.038
hexose metabolic processGO:0019318980.038
monosaccharide metabolic processGO:00059961060.037
cellular protein catabolic processGO:00442571550.037
immune effector processGO:00022523210.037
transmission of nerve impulseGO:0019226760.037
response to molecule of bacterial originGO:00022371430.036
glycolipid catabolic processGO:001937750.036
cellular amino acid metabolic processGO:00065201030.036
alcohol metabolic processGO:00060661160.034
regulation of cellular amine metabolic processGO:0033238200.034
vitamin metabolic processGO:0006766230.033
transmembrane transportGO:00550854120.033
regulation of membrane potentialGO:00423911920.032
nucleotide metabolic processGO:00091173320.032
regulation of defense responseGO:00313472330.032
nucleoside phosphate metabolic processGO:00067533380.032
regulation of cellular amino acid metabolic processGO:000652150.031
anatomical structure homeostasisGO:00602491450.031
respiratory system developmentGO:00605411900.031
regulation of secretion by cellGO:19035302490.030
regulation of hydrolase activityGO:00513362460.029
leukocyte mediated immunityGO:00024431740.029
sulfur compound metabolic processGO:00067901000.028
cellular macromolecule catabolic processGO:00442652060.028
lipid biosynthetic processGO:00086101790.028
cellular modified amino acid metabolic processGO:0006575630.027
organonitrogen compound biosynthetic processGO:19015661920.027
ceramide biosynthetic processGO:0046513200.026
cellular response to organonitrogen compoundGO:00714171450.026
amine metabolic processGO:0009308450.026
cation transmembrane transportGO:00986552660.025
adaptive immune responseGO:00022501550.025
camera type eye developmentGO:00430102660.025
peptide metabolic processGO:0006518460.025
macromolecule catabolic processGO:00090572810.025
monocarboxylic acid metabolic processGO:00327871910.025
nitrogen compound transportGO:00717052710.024
peptidyl amino acid modificationGO:00181933360.024
glycosyl compound metabolic processGO:19016572460.024
proteolysis involved in cellular protein catabolic processGO:00516031470.024
glycosphingolipid catabolic processGO:004647950.024
positive regulation of proteolysisGO:0045862850.024
negative regulation of cellular protein metabolic processGO:00322692470.024
hindbrain developmentGO:00309021280.024
regulation of cellular ketone metabolic processGO:0010565660.024
regulation of vascular smooth muscle contractionGO:000305610.023
organelle assemblyGO:00709251770.023
multicellular organismal signalingGO:0035637910.023
ion transmembrane transportGO:00342203610.023
phospholipid transfer to membraneGO:000664920.023
nuclear divisionGO:00002801580.023
lung developmentGO:00303241640.023
response to organonitrogen compoundGO:00102432460.023
regulation of peptidase activityGO:0052547960.022
multicellular organismal homeostasisGO:00488711640.022
neuromuscular process controlling balanceGO:0050885590.022
oligosaccharide catabolic processGO:000931320.022
respiratory tube developmentGO:00303231670.022
neuronal action potentialGO:0019228540.022
modification dependent protein catabolic processGO:00199411330.022
nucleobase containing small molecule metabolic processGO:00550863520.022
purine containing compound metabolic processGO:00725213110.022
organic hydroxy compound metabolic processGO:19016152030.022
regulation of proteolysisGO:00301621640.021
organic anion transportGO:00157111370.021
purine ribonucleoside monophosphate metabolic processGO:0009167800.021
regulation of cell morphogenesis involved in differentiationGO:00107691510.021
cytokine productionGO:00018163190.021
anion transmembrane transportGO:0098656710.021
lateral inhibitionGO:004633110.021
response to acid chemicalGO:00011011110.021
reactive oxygen species metabolic processGO:0072593840.021
maintenance of locationGO:0051235890.020
learning or memoryGO:00076111480.020
ubiquitin dependent protein catabolic processGO:00065111290.019
positive regulation of apoptotic processGO:00430652170.019
negative regulation of intracellular signal transductionGO:19025321670.019
cellular amine metabolic processGO:0044106440.019
cell type specific apoptotic processGO:00972852680.019
carbohydrate derivative biosynthetic processGO:19011371830.019
oligosaccharide metabolic processGO:0009311110.019
tissue homeostasisGO:00018941150.019
cytoplasmic transportGO:00164822340.019
reactive nitrogen species metabolic processGO:200105700.019
striated muscle tissue developmentGO:00147062930.019
sensory perception of soundGO:0007605970.019
membrane organizationGO:00610242450.019
positive regulation of protein modification processGO:00314012990.019
glycosyl compound catabolic processGO:19016582060.018
apoptotic signaling pathwayGO:00971903060.018
organic acid transportGO:00158491010.018
single fertilizationGO:0007338820.018
regulation of system processGO:00440572000.018
amino acid transportGO:0006865610.018
regulation of cytokine productionGO:00018172660.018
dephosphorylationGO:00163111290.018
reactive oxygen species biosynthetic processGO:190340980.018
epidermis developmentGO:00085441870.018
water soluble vitamin metabolic processGO:0006767100.018
cation homeostasisGO:00550802120.018
positive regulation of cellular amino acid metabolic processGO:004576430.017
multicellular organismal macromolecule catabolic processGO:004426610.017
sphingosine metabolic processGO:000667040.017
blood vessel morphogenesisGO:00485142850.017
regulation of interleukin 1 alpha productionGO:003265040.017
gland developmentGO:00487323300.017
negative regulation of protein metabolic processGO:00512482820.017
regulation of cell migrationGO:00303342190.017
inflammatory responseGO:00069542440.017
dna recombinationGO:0006310920.017
epithelial cell proliferationGO:00506731740.017
glycosylationGO:0070085620.017
myelinationGO:0042552740.017
cation transportGO:00068123990.017
membrane lipid catabolic processGO:004646680.017
dna metabolic processGO:00062593030.017
glycoprotein metabolic processGO:00091001160.016
ear developmentGO:00435832000.016
negative regulation of cell proliferationGO:00082852960.016
forebrain developmentGO:00309003020.016
nucleoside catabolic processGO:00091642060.016
cognitionGO:00508901490.016
regulation of reactive oxygen species metabolic processGO:2000377400.016
positive regulation of immune effector processGO:00026991070.016
renal system developmentGO:00720012250.016
metal ion homeostasisGO:00550651890.016
regulation of cell cycleGO:00517262810.016
response to organic cyclic compoundGO:00140701980.016
chemotaxisGO:00069352470.016
leukocyte mediated cytotoxicityGO:0001909620.016
heterocycle catabolic processGO:00467002800.016
stem cell differentiationGO:00488632680.016
fertilizationGO:00095661270.016
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.016
axonogenesisGO:00074092740.016
somatotropin secreting cell developmentGO:006013320.016
macromolecule glycosylationGO:0043413550.015
cellular nitrogen compound catabolic processGO:00442702800.015
n acetylglucosamine metabolic processGO:000604430.015
organophosphate catabolic processGO:00464342320.015
lipid catabolic processGO:0016042690.015
kidney developmentGO:00018222130.015
carboxylic acid transportGO:00469421000.015
heart morphogenesisGO:00030071780.015
glycosylceramide catabolic processGO:004647720.015
intracellular protein transportGO:00068862040.015
regulation of lymphocyte activationGO:00512492400.015
protein catabolic processGO:00301632210.015
regulation of apoptotic signaling pathwayGO:20012331970.015
negative regulation of cytokine productionGO:0001818840.015
regionalizationGO:00030023370.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
atp catabolic processGO:0006200550.015
posttranscriptional regulation of gene expressionGO:00106081550.015
neural tube developmentGO:00219151600.015
positive regulation of programmed cell deathGO:00430682180.015
response to lipopolysaccharideGO:00324961280.015
negative regulation of phosphate metabolic processGO:00459361840.014
negative regulation of nervous system developmentGO:00519611560.014
modification dependent macromolecule catabolic processGO:00436321330.014
regulation of organelle organizationGO:00330432890.014
anion transportGO:00068201770.014
muscle tissue developmentGO:00605373080.014
cellular ketone metabolic processGO:0042180840.014
cofactor transportGO:005118140.014
glycerolipid metabolic processGO:00464861220.014
regulation of membrane protein ectodomain proteolysisGO:005104330.014
purine nucleoside triphosphate metabolic processGO:00091442260.014
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.014
glycosylceramide metabolic processGO:000667740.014
organelle localizationGO:00516401790.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.014
purine nucleoside metabolic processGO:00422782410.014
regulation of protein maturationGO:1903317960.014
neurotransmitter transportGO:0006836760.014
protein secretionGO:00093061110.014
regulation of protein localizationGO:00328802310.014
negative regulation of immune system processGO:00026832090.014
response to light stimulusGO:00094161350.014
skin developmentGO:00435882200.014
fat soluble vitamin biosynthetic processGO:004236240.014
aromatic compound catabolic processGO:00194392860.013
ribonucleoside monophosphate metabolic processGO:0009161800.013
alanine transportGO:003232840.013
lipid localizationGO:00108761260.013
stem cell developmentGO:00488642190.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.013
extracellular structure organizationGO:00430621480.013
positive regulation of peptidase activityGO:0010952490.013
synaptic transmissionGO:00072683290.013
action potentialGO:0001508780.013
positive regulation of macroautophagyGO:001623930.013
inorganic cation transmembrane transportGO:00986622070.013
establishment of vesicle localizationGO:0051650810.013
nucleoside phosphate catabolic processGO:19012922220.013
regulation of lymphocyte mediated immunityGO:0002706840.013
cellular response to lipidGO:00713961450.013
nucleotide catabolic processGO:00091662170.013
homeostasis of number of cellsGO:00488722100.013
negative regulation of dna replicationGO:000815640.013
t cell activationGO:00421102890.013
hematopoietic progenitor cell differentiationGO:00022441430.013
innate immune responseGO:00450871570.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.013
phagolysosome assemblyGO:000184530.013
regulation of reactive oxygen species biosynthetic processGO:190342620.013
regulation of systemic arterial blood pressure by carotid body chemoreceptor signalingGO:000302710.013
lipid transportGO:0006869980.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
sensory perception of light stimulusGO:0050953540.012
sensory perception of mechanical stimulusGO:00509541070.012
cellular response to cytokine stimulusGO:00713451890.012
interleukin 8 productionGO:003263740.012
cell killingGO:0001906670.012
axon ensheathmentGO:0008366760.012
defense response to other organismGO:00985421970.012
positive regulation of cell motilityGO:20001471160.012
lymphocyte proliferationGO:00466511640.012
embryonic epithelial tube formationGO:00018381300.012
endocytosisGO:00068971680.012
negative regulation of phosphorylationGO:00423261660.012
regulation of anatomical structure sizeGO:00900661780.012
embryonic organ morphogenesisGO:00485622760.012
regulation of transferase activityGO:00513382630.012
positive regulation of cell activationGO:00508671580.012
production of molecular mediator of immune responseGO:00024401030.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
purine ribonucleotide catabolic processGO:00091542080.012
negative regulation of cellular amine metabolic processGO:003323910.012
epithelial cell developmentGO:00020641590.012
regulation of epithelial cell proliferationGO:00506781410.012
spermatid differentiationGO:00485151150.012
cellular homeostasisGO:00197252400.012
nucleotide sugar metabolic processGO:000922540.012
bone remodelingGO:0046849530.012
regulation of adaptive immune responseGO:0002819900.012
t cell proliferationGO:00420981200.012
angiogenesisGO:00015252010.012
cell adhesionGO:00071553290.012
gliogenesisGO:00420631410.012
ensheathment of neuronsGO:0007272760.012
urogenital system developmentGO:00016552610.012
nucleoside monophosphate metabolic processGO:0009123850.012
positive regulation of adaptive immune responseGO:0002821610.012
segmentationGO:0035282930.011
regulation of vesicle mediated transportGO:00606271390.011
protein hydroxylationGO:001812640.011
germ cell developmentGO:00072811850.011
sphingolipid biosynthetic processGO:0030148260.011
purine nucleoside monophosphate catabolic processGO:0009128580.011
cellular protein complex assemblyGO:00436231160.011
regulation of t cell mediated cytotoxicityGO:0001914180.011
purine nucleoside monophosphate metabolic processGO:0009126810.011
leukocyte proliferationGO:00706611720.011
t cell mediated cytotoxicityGO:0001913260.011
purine nucleotide metabolic processGO:00061633020.011
cellular response to organic cyclic compoundGO:0071407870.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
bone developmentGO:00603481200.011
muscle cell differentiationGO:00426922610.011
liposaccharide metabolic processGO:1903509270.011
multicellular organismal protein catabolic processGO:004425410.011
negative regulation of cellular amino acid metabolic processGO:004576300.011
protein glycosylationGO:0006486550.011
negative regulation of protein modification processGO:00314001630.011
cellular response to molecule of bacterial originGO:0071219830.011
cellular carbohydrate metabolic processGO:00442621190.011
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.011
nuclear transportGO:00511691390.011
positive regulation of cholesterol metabolic processGO:009020530.011
fucosylationGO:003606590.011
regulation of cell motilityGO:20001452360.011
cellular response to biotic stimulusGO:0071216920.011
regulation of intracellular transportGO:00323861590.011
regulation of multi organism processGO:00439001110.011
smoothened signaling pathwayGO:00072241050.011
beta amyloid clearanceGO:009724220.011
mechanoreceptor differentiationGO:0042490670.011
regulation of cell activationGO:00508652890.011
proteasomal protein catabolic processGO:0010498980.011
cell cell recognitionGO:0009988440.010
regulation of cytoplasmic transportGO:19036491120.010
neuron projection guidanceGO:00974851410.010
leukocyte homeostasisGO:0001776790.010
purine ribonucleotide metabolic processGO:00091502900.010
lymphocyte homeostasisGO:0002260640.010
membrane tubulationGO:009732040.010
regulation of leukocyte mediated immunityGO:00027031040.010
muscle system processGO:00030121410.010
positive regulation of cytokine productionGO:00018191740.010
positive regulation of interleukin 1 alpha productionGO:003273040.010
organophosphate biosynthetic processGO:00904071220.010
positive regulation of cell deathGO:00109422240.010
telencephalon developmentGO:00215371860.010
neuron projection extensionGO:1990138640.010
regulation of cysteine type endopeptidase activityGO:2000116650.010
purine containing compound catabolic processGO:00725232130.010
immunoglobulin productionGO:0002377730.010
atp metabolic processGO:0046034750.010
ribose phosphate metabolic processGO:00196932910.010

Naglu disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.531
disease of metabolismDOID:001466700.531
lysosomal storage diseaseDOID:321100.146
lipid storage diseaseDOID:945500.146
nervous system diseaseDOID:86300.119
disease of anatomical entityDOID:700.119
central nervous system diseaseDOID:33100.114
cerebral degenerationDOID:144300.042
brain diseaseDOID:93600.042
sensory system diseaseDOID:005015500.039
sphingolipidosisDOID:192700.027
connective tissue diseaseDOID:6500.023
musculoskeletal system diseaseDOID:1700.023
neurodegenerative diseaseDOID:128900.021
immune system diseaseDOID:291400.014
bone diseaseDOID:008000100.012
mucopolysaccharidosisDOID:1279800.011
eye diseaseDOID:561400.011
eye and adnexa diseaseDOID:149200.011
retinal diseaseDOID:567900.011
dementiaDOID:130700.010
disease of mental healthDOID:15000.010
cognitive disorderDOID:156100.010