Mus musculus

41 known processes

Loxl2

lysyl oxidase-like 2

(Aliases: 4930526G11Rik,MGC102220,1110004B06Rik,9430067E15Rik)

Loxl2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell adhesionGO:00071553290.241
extracellular matrix organizationGO:00301981470.204
Human
regulation of cell adhesionGO:00301551540.163
small gtpase mediated signal transductionGO:0007264970.130
regulation of cell motilityGO:20001452360.129
extracellular structure organizationGO:00430621480.125
Human
muscle cell differentiationGO:00426922610.122
regulation of cell migrationGO:00303342190.122
cell cell adhesionGO:0098609410.119
cellular amino acid metabolic processGO:00065201030.112
ras protein signal transductionGO:0007265770.110
cell recognitionGO:0008037830.108
regulation of apoptotic signaling pathwayGO:20012331970.099
wound healingGO:00420601570.096
positive regulation of cellular amino acid metabolic processGO:004576430.092
muscle cell developmentGO:00550011330.088
blood vessel morphogenesisGO:00485142850.083
Human
response to growth factorGO:00708481980.082
rho protein signal transductionGO:0007266320.082
actin cytoskeleton organizationGO:00300362200.080
apoptotic signaling pathwayGO:00971903060.080
cell substrate adhesionGO:00315891300.079
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.077
regulation of cellular ketone metabolic processGO:0010565660.076
regulation of cellular component biogenesisGO:00440871810.075
renal system developmentGO:00720012250.074
single organism cell adhesionGO:00986021560.074
regulation of cellular amine metabolic processGO:0033238200.073
regulation of synaptic growth at neuromuscular junctionGO:000858240.073
single organismal cell cell adhesionGO:00163371310.072
cellular response to growth factor stimulusGO:00713631970.072
regulation of purine nucleotide metabolic processGO:19005421690.072
cellular ketone metabolic processGO:0042180840.069
regulation of cellular amino acid metabolic processGO:000652150.067
macromolecule catabolic processGO:00090572810.066
striated muscle cell developmentGO:00550021250.065
cell matrix adhesionGO:0007160680.064
actin filament organizationGO:00070151130.064
muscle tissue developmentGO:00605373080.063
bone developmentGO:00603481200.061
positive regulation of cellular amine metabolic processGO:003324050.060
striated muscle tissue developmentGO:00147062930.059
cellular amine metabolic processGO:0044106440.059
protein processingGO:00164851630.059
response to acid chemicalGO:00011011110.058
cardiac muscle tissue developmentGO:00487381300.058
stem cell differentiationGO:00488632680.057
Human
protein maturationGO:00516041760.056
i kappab kinase nf kappab signalingGO:0007249850.055
peptidyl amino acid modificationGO:00181933360.054
negative regulation of cell migrationGO:0030336590.054
response to decreased oxygen levelsGO:0036293590.053
cellular response to organonitrogen compoundGO:00714171450.053
regulation of endopeptidase activityGO:0052548890.052
purine nucleotide metabolic processGO:00061633020.051
negative regulation of phosphorylationGO:00423261660.050
skeletal muscle organ developmentGO:00605381630.049
skeletal system developmentGO:00015013560.049
forebrain developmentGO:00309003020.048
regulation of proteolysisGO:00301621640.047
ear developmentGO:00435832000.046
positive regulation of cell developmentGO:00107202370.046
negative regulation of synapse assemblyGO:005196430.046
mapk cascadeGO:00001652810.046
sensory organ morphogenesisGO:00905962420.045
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.045
regulation of hydrolase activityGO:00513362460.044
organelle assemblyGO:00709251770.044
epithelial to mesenchymal transitionGO:0001837470.044
Human
nucleoside phosphate catabolic processGO:19012922220.043
negative regulation of apoptotic signaling pathwayGO:20012341040.043
protein hydroxylationGO:001812640.042
engulfment of apoptotic cellGO:004365230.042
ameboidal type cell migrationGO:00016671280.042
Human
oxidation reduction processGO:00551143420.041
Human Mouse Fly
purine ribonucleotide catabolic processGO:00091542080.041
response to transforming growth factor betaGO:0071559880.040
cellular response to transforming growth factor beta stimulusGO:0071560880.040
epithelial cell proliferationGO:00506731740.039
Human
positive regulation of nervous system developmentGO:00519622210.039
epibolyGO:009050480.038
wnt signaling pathwayGO:00160551880.038
cardiac chamber developmentGO:00032051080.038
regulation of epithelial cell proliferationGO:00506781410.037
positive regulation of cell adhesionGO:0045785800.037
regulation of ras protein signal transductionGO:00465781140.036
cardiac muscle tissue morphogenesisGO:0055008440.036
myotube differentiationGO:00149021050.036
mesenchymal cell differentiationGO:00487621070.036
Human
lung developmentGO:00303241640.036
carbohydrate derivative catabolic processGO:19011362310.036
protein catabolic processGO:00301632210.034
negative regulation of protein metabolic processGO:00512482820.034
response to organonitrogen compoundGO:00102432460.034
positive regulation of protein modification processGO:00314012990.034
aromatic compound catabolic processGO:00194392860.033
nucleobase containing small molecule metabolic processGO:00550863520.033
regulation of cytokine productionGO:00018172660.033
negative regulation of cell motilityGO:2000146610.032
positive regulation of growthGO:00459271040.032
signal transduction in absence of ligandGO:0038034550.031
positive regulation of cellular component biogenesisGO:0044089940.031
tissue homeostasisGO:00018941150.031
negative regulation of protein processingGO:0010955790.031
fat cell differentiationGO:00454441600.031
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.030
regulation of striated muscle cell differentiationGO:0051153810.030
regulation of protein kinase activityGO:00458592320.030
negative regulation of cellular protein metabolic processGO:00322692470.030
cellular response to lipidGO:00713961450.030
regulation of wnt signaling pathwayGO:00301111230.030
cell junction organizationGO:0034330770.029
negative regulation of phosphate metabolic processGO:00459361840.029
heterocycle catabolic processGO:00467002800.029
morphogenesis of an epithelial sheetGO:0002011270.028
regulation of cell projection organizationGO:00313442060.028
response to peptide hormoneGO:00434341270.028
stem cell developmentGO:00488642190.028
Human
glycosyl compound metabolic processGO:19016572460.028
nucleoside triphosphate metabolic processGO:00091412300.028
ribonucleotide catabolic processGO:00092612080.028
membrane organizationGO:00610242450.027
regulation of nucleotide metabolic processGO:00061401690.027
oviduct developmentGO:006006630.027
negative regulation of cell proliferationGO:00082852960.027
regulation of rho protein signal transductionGO:0035023710.027
skin developmentGO:00435882200.027
organ growthGO:00352651170.026
trabecula morphogenesisGO:0061383400.026
connective tissue developmentGO:00614481790.026
anatomical structure maturationGO:0071695490.026
guanosine containing compound metabolic processGO:19010681440.026
mesodermal cell migrationGO:000807840.025
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.025
purine nucleoside triphosphate catabolic processGO:00091462030.025
regulation of peptidase activityGO:0052547960.025
organonitrogen compound catabolic processGO:19015652640.025
protein secretionGO:00093061110.024
negative regulation of endopeptidase activityGO:0010951440.024
negative regulation of cellular amine metabolic processGO:003323910.024
extrinsic apoptotic signaling pathwayGO:00971911260.024
purine containing compound metabolic processGO:00725213110.024
negative regulation of wnt signaling pathwayGO:0030178730.024
negative regulation of cellular component organizationGO:00511291940.024
cellular response to cytokine stimulusGO:00713451890.024
interleukin 8 secretionGO:007260630.023
negative regulation of molecular functionGO:00440922580.023
positive regulation of protein phosphorylationGO:00019342420.023
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiationGO:200072120.023
endothelial cell proliferationGO:0001935270.023
Human
response to oxidative stressGO:00069791230.023
amine metabolic processGO:0009308450.022
embryonic organ morphogenesisGO:00485622760.022
regulation of organelle organizationGO:00330432890.022
ossificationGO:00015032160.022
response to oxygen levelsGO:0070482620.022
positive regulation of cell substrate adhesionGO:0010811470.022
leukocyte differentiationGO:00025213420.022
cytokine productionGO:00018163190.022
response to peptideGO:19016521360.022
regulation of endocytic recyclingGO:200113530.022
head morphogenesisGO:0060323340.022
epithelial cell developmentGO:00020641590.022
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.022
regulation of response to woundingGO:19030341890.022
circulatory system processGO:00030131970.022
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathwayGO:005148240.021
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.021
regulation of neuron differentiationGO:00456642810.021
gtp metabolic processGO:00460391440.021
urogenital system developmentGO:00016552610.021
transmembrane transportGO:00550854120.021
regulation of cellular catabolic processGO:00313292420.021
purine ribonucleoside triphosphate metabolic processGO:00092052200.021
canonical wnt signaling pathwayGO:00600701300.021
regulation of muscle tissue developmentGO:1901861970.021
purine nucleoside catabolic processGO:00061522050.021
cerebral cortex developmentGO:0021987860.021
ear morphogenesisGO:00424711180.021
negative regulation of nervous system developmentGO:00519611560.021
sensory perceptionGO:00076002450.021
cation transportGO:00068123990.021
cellular response to external stimulusGO:0071496880.021
cellular nitrogen compound catabolic processGO:00442702800.021
cellular response to hormone stimulusGO:00328701500.021
organophosphate catabolic processGO:00464342320.021
kidney developmentGO:00018222130.021
response to fibroblast growth factorGO:0071774470.021
endoderm developmentGO:0007492450.021
endochondral bone morphogenesisGO:0060350500.021
negative regulation of protein maturationGO:1903318790.020
regulation of protein processingGO:0070613960.020
regulation of anatomical structure sizeGO:00900661780.020
cellular response to acid chemicalGO:0071229680.020
respiratory tube developmentGO:00303231670.020
response to inorganic substanceGO:0010035960.020
Human
regulation of protein maturationGO:1903317960.020
positive regulation of cell growthGO:0030307330.020
development of primary sexual characteristicsGO:00451371430.020
glycosyl compound catabolic processGO:19016582060.020
anatomical structure homeostasisGO:00602491450.019
myeloid cell differentiationGO:00300992330.019
negative regulation of angiogenesisGO:0016525250.019
angiogenesisGO:00015252010.019
Human
heart morphogenesisGO:00030071780.019
ribonucleoside catabolic processGO:00424542060.019
nucleoside phosphate metabolic processGO:00067533380.019
axonogenesisGO:00074092740.019
immune effector processGO:00022523210.019
neuron projection guidanceGO:00974851410.019
microtubule based processGO:00070172360.019
cellular response to amino acid stimulusGO:0071230290.019
asymmetric stem cell divisionGO:009872230.019
regulation of peptidyl tyrosine phosphorylationGO:0050730930.019
digestive tract developmentGO:00485651900.019
purine nucleotide catabolic processGO:00061952110.019
ribonucleotide metabolic processGO:00092592910.019
notochord developmentGO:0030903200.019
cholesterol homeostasisGO:0042632440.018
respiratory system developmentGO:00605411900.018
bmp signaling pathwayGO:0030509930.018
cellular protein complex assemblyGO:00436231160.018
regulation of vesicle mediated transportGO:00606271390.018
purine ribonucleoside triphosphate catabolic processGO:00092071990.018
lateral inhibitionGO:004633110.018
cellular protein catabolic processGO:00442571550.018
plasma membrane organizationGO:0007009900.018
regulation of mapk cascadeGO:00434082480.018
defense response to other organismGO:00985421970.018
purine ribonucleoside metabolic processGO:00461282410.018
response to extracellular stimulusGO:00099911270.018
nucleotide metabolic processGO:00091173320.018
inner ear morphogenesisGO:00424721010.017
meiotic nuclear divisionGO:00071261150.017
dendritic spine maintenanceGO:009706240.017
response to metal ionGO:0010038470.017
Human
regulation of nucleoside metabolic processGO:00091181300.017
retinal blood vessel morphogenesisGO:006130430.017
phagocytosisGO:0006909660.017
intracellular protein transportGO:00068862040.017
purine ribonucleotide metabolic processGO:00091502900.017
transforming growth factor beta receptor signaling pathwayGO:0007179710.017
regulation of cell cycleGO:00517262810.017
response to molecule of bacterial originGO:00022371430.017
molting cycleGO:0042303900.017
positive regulation of endocytosisGO:0045807420.017
response to retinoic acidGO:0032526560.017
regulation of cytoskeleton organizationGO:00514931220.017
negative regulation of proteolysisGO:0045861740.017
skeletal myofibril assemblyGO:001486640.017
synapse organizationGO:00508081250.017
cellular response to inorganic substanceGO:0071241370.017
regulation of osteoblast differentiationGO:0045667670.016
cell growthGO:00160491300.016
peptidyl tyrosine phosphorylationGO:00181081430.016
cellular response to biotic stimulusGO:0071216920.016
endocytosisGO:00068971680.016
regulation of endocytosisGO:0030100690.016
digestive system developmentGO:00551232000.016
maintenance of locationGO:0051235890.016
camera type eye developmentGO:00430102660.016
negative regulation of cell developmentGO:00107211690.016
nucleoside triphosphate catabolic processGO:00091432050.016
response to endoplasmic reticulum stressGO:0034976530.016
cellular component assembly involved in morphogenesisGO:00109271390.016
collagen biosynthetic processGO:003296470.016
gastrulationGO:00073691160.016
actin mediated cell contractionGO:0070252150.016
protein localization to organelleGO:00333651850.016
biomineral tissue developmentGO:0031214640.015
regulation of cysteine type endopeptidase activityGO:2000116650.015
nucleotide catabolic processGO:00091662170.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.015
regulation of cellular response to stressGO:00801351590.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.015
response to organic cyclic compoundGO:00140701980.015
negative regulation of protein phosphorylationGO:00019331260.015
regulation of body fluid levelsGO:00508781620.015
regulation of nucleotide catabolic processGO:00308111220.015
regulation of vasculature developmentGO:1901342880.015
positive regulation of cell projection organizationGO:0031346950.015
positive regulation of kinase activityGO:00336741550.015
purine containing compound catabolic processGO:00725232130.015
muscle fiber developmentGO:0048747760.015
transforming growth factor beta2 productionGO:003290620.015
endomembrane system organizationGO:00102561470.015
positive regulation of neuron projection developmentGO:0010976790.015
limb morphogenesisGO:00351081490.015
meiotic cell cycleGO:00513211220.015
hematopoietic progenitor cell differentiationGO:00022441430.015
glycoprotein metabolic processGO:00091001160.015
intrinsic apoptotic signaling pathwayGO:00971931320.015
regulation of myotube differentiationGO:0010830620.015
cell type specific apoptotic processGO:00972852680.015
skeletal system morphogenesisGO:00487052030.015
negative regulation of hydrolase activityGO:0051346710.014
protein targetingGO:00066051430.014
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.014
bone morphogenesisGO:0060349780.014
negative regulation of intracellular signal transductionGO:19025321670.014
tube formationGO:00351481400.014
multicellular organismal homeostasisGO:00488711640.014
tissue migrationGO:0090130680.014
Human
nuclear divisionGO:00002801580.014
nucleoside catabolic processGO:00091642060.014
positive regulation of cell migrationGO:00303351090.014
telencephalon developmentGO:00215371860.014
wound healing spreading of cellsGO:004431980.014
regulation of interleukin 8 productionGO:003267730.014
peptidyl tyrosine modificationGO:00182121450.014
collagen fibril organizationGO:0030199320.014
Human
developmental maturationGO:00217001930.014
organelle fissionGO:00482851700.014
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.014
chemotaxisGO:00069352470.014
regulation of angiogenesisGO:0045765810.014
regulation of cardiac muscle tissue growthGO:0055021260.014
positive regulation of transferase activityGO:00513471670.014
myotube cell developmentGO:0014904600.014
purine nucleoside triphosphate metabolic processGO:00091442260.014
developmental cell growthGO:0048588840.014
ubiquitin dependent protein catabolic processGO:00065111290.014
nucleoside metabolic processGO:00091162460.013
ribose phosphate metabolic processGO:00196932910.013
cardiac chamber morphogenesisGO:0003206930.013
positive regulation of cell deathGO:00109422240.013
cell junction assemblyGO:0034329520.013
cell divisionGO:00513011200.013
negative regulation of blood vessel morphogenesisGO:2000181250.013
regulation of cellular response to growth factor stimulusGO:0090287820.013
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.013
cardiac cell developmentGO:0055006410.013
modification dependent protein catabolic processGO:00199411330.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
pallium developmentGO:00215431200.013
nitrogen compound transportGO:00717052710.013
sensory perception of mechanical stimulusGO:00509541070.013
establishment of tissue polarityGO:0007164280.013
striated muscle myosin thick filament assemblyGO:007168810.013
regulation of fat cell differentiationGO:0045598810.013
neuron recognitionGO:0008038250.013
regulation of cell sizeGO:0008361720.013
regulation of endothelial cell proliferationGO:0001936230.013
inflammatory responseGO:00069542440.013
negative regulation of gastrulationGO:200054230.012
synapse assemblyGO:0007416560.012
regulation of kinase activityGO:00435492490.012
positive regulation of neuron projection regenerationGO:007057220.012
fibroblast growth factor receptor signaling pathwayGO:0008543460.012
regulation of cell substrate adhesionGO:0010810730.012
developmental growth involved in morphogenesisGO:00605601380.012
mitotic cell cycleGO:00002781950.012
negative regulation of growthGO:0045926990.012
regulation of protein complex assemblyGO:0043254830.012
negative regulation of cell adhesionGO:0007162450.012
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.012
negative regulation of peptidase activityGO:0010466460.012
regulation of organ growthGO:0046620610.012
positive regulation of protein kinase activityGO:00458601440.012
regulation of secretionGO:00510462740.012
modification dependent macromolecule catabolic processGO:00436321330.012
learningGO:0007612980.012
mitotic cell cycle processGO:19030471590.012
smooth muscle tissue developmentGO:0048745220.012
regulation of ossificationGO:00302781120.012
protein foldingGO:0006457280.012
compound eye developmentGO:004874910.012
oocyte constructionGO:000730820.012
nephron epithelium developmentGO:0072009920.012
purine nucleoside metabolic processGO:00422782410.012
skeletal muscle satellite cell maintenance involved in skeletal muscle regenerationGO:001483430.011
neuron migrationGO:00017641220.011
bone trabecula morphogenesisGO:0061430120.011
lipid homeostasisGO:0055088630.011
positive regulation of mapk cascadeGO:00434101700.011
peptidyl serine modificationGO:0018209830.011
cytoplasmic transportGO:00164822340.011
protein modification by small protein conjugation or removalGO:00706472070.011
negative regulation of cellular response to growth factor stimulusGO:0090288460.011
regulation of transferase activityGO:00513382630.011
ribonucleoside metabolic processGO:00091192450.011
positive regulation of interleukin 8 productionGO:003275720.011
negative regulation of protein modification processGO:00314001630.011
positive regulation of programmed cell deathGO:00430682180.011
regulation of neuron projection developmentGO:00109751690.011
guanosine containing compound catabolic processGO:19010691440.011
body morphogenesisGO:0010171450.011
covalent chromatin modificationGO:00165691630.011
Human
cardiocyte differentiationGO:0035051870.011
endoderm formationGO:0001706200.011
regulation of canonical wnt signaling pathwayGO:0060828820.011
ubiquitin dependent smad protein catabolic processGO:003057920.011
regulation of extent of cell growthGO:0061387520.011
cardiac muscle cell differentiationGO:0055007690.011
oocyte axis specificationGO:000730920.011
regulation of defense responseGO:00313472330.011
regulation of rho gtpase activityGO:0032319580.011
regulation of system processGO:00440572000.011
focal adhesion assemblyGO:0048041190.011
synaptic transmissionGO:00072683290.011
lateral line system developmentGO:004892510.011
appendage developmentGO:00487361660.011
uterus morphogenesisGO:006103820.011
myeloid leukocyte differentiationGO:00025731190.011
regulation of heart growthGO:0060420310.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
microglia developmentGO:001400520.011
epithelial cell migrationGO:0010631630.011
Human
cell chemotaxisGO:0060326810.011
regulation of protein transportGO:00512231630.010
positive regulation of neuron differentiationGO:00456661410.010
positive regulation of proteolysisGO:0045862850.010
negative regulation of canonical wnt signaling pathwayGO:0090090510.010
neuron deathGO:00709971540.010
neurotransmitter transportGO:0006836760.010
cellular response to extracellular stimulusGO:0031668810.010
neural precursor cell proliferationGO:00613511210.010
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.010
learning or memoryGO:00076111480.010
interleukin 8 productionGO:003263740.010
negative regulation of hormone metabolic processGO:003235140.010
regulation of neuron migrationGO:2001222220.010
positive regulation of cell activationGO:00508671580.010
morphogenesis of embryonic epitheliumGO:00163311590.010

Loxl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.097
disease of anatomical entityDOID:700.097
connective tissue diseaseDOID:6500.051
bone diseaseDOID:008000100.046
bone development diseaseDOID:008000600.046
nervous system diseaseDOID:86300.021
muscular diseaseDOID:008000000.018
muscle tissue diseaseDOID:6600.012
myopathyDOID:42300.012
eye diseaseDOID:561400.011
eye and adnexa diseaseDOID:149200.011
retinal diseaseDOID:567900.011
sensory system diseaseDOID:005015500.011