Mus musculus

33 known processes

Smc3

structural maintenace of chromosomes 3

(Aliases: HCAP,SMC-3,Mmip1,Bamacan,Cspg6,SmcD)

Smc3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of dna endoreduplicationGO:003287530.995
Human
sister chromatid cohesionGO:0007062120.990
Human Yeast Zebrafish
negative regulation of dna dependent dna replicationGO:200010410.983
Human
dna repairGO:00062811070.971
Yeast
meiotic cell cycle processGO:1903046770.929
Yeast
negative regulation of dna replicationGO:000815640.896
Human
chromosome organization involved in meiosisGO:0070192390.865
Yeast
meiotic cell cycleGO:00513211220.864
meiotic nuclear divisionGO:00071261150.856
synapsisGO:0007129340.851
Yeast
histone methylationGO:0016571710.846
dna metabolic processGO:00062593030.843
Human Yeast
histone modificationGO:00165701590.838
protein methylationGO:0006479810.828
chromatin assembly or disassemblyGO:0006333160.815
protein alkylationGO:0008213810.812
heterochromatin organizationGO:007082840.803
regulation of chromatin modificationGO:1903308570.739
development of primary sexual characteristicsGO:00451371430.731
double strand break repairGO:0006302480.729
Yeast
response to ionizing radiationGO:0010212420.717
mitotic sister chromatid cohesionGO:000706410.713
Yeast Zebrafish
stem cell maintenanceGO:00198271300.709
regulation of cell cycleGO:00517262810.677
Human
dna replicationGO:0006260520.650
Human
genetic imprintingGO:0071514270.649
spermatogenesisGO:00072832840.649
chromatin modificationGO:00165681870.596
gonad developmentGO:00084061410.585
organelle fissionGO:00482851700.575
dna replication independent nucleosome assemblyGO:000633610.572
dna endoreduplicationGO:004202340.566
Human
peptidyl lysine modificationGO:0018205770.551
seminiferous tubule developmentGO:0072520140.530
regulation of dna replicationGO:0006275170.522
Human
covalent chromatin modificationGO:00165691630.489
dna conformation changeGO:0071103370.487
developmental maturationGO:00217001930.481
negative regulation of gene expression epigeneticGO:0045814150.467
methylationGO:00322591340.458
negative regulation of histone methylationGO:0031061100.458
macromolecule methylationGO:00434141200.457
stem cell differentiationGO:00488632680.452
gene silencingGO:0016458380.446
dendrite developmentGO:00163581150.417
proprioceptionGO:001923040.416
mitotic sister chromatid segregationGO:0000070140.406
Yeast Zebrafish
cellular response to dna damage stimulusGO:00069742070.401
Yeast
dna dependent dna replication maintenance of fidelityGO:004500530.398
ventricular system developmentGO:0021591270.384
mitotic cell cycle processGO:19030471590.380
Human Yeast Zebrafish
regulation of cellular amino acid metabolic processGO:000652150.373
regulation of chromatin organizationGO:1902275570.366
neuron maturationGO:0042551290.365
mitotic cell cycleGO:00002781950.361
Human Yeast Zebrafish
nuclear divisionGO:00002801580.358
response to x rayGO:0010165110.340
cellular ketone metabolic processGO:0042180840.337
meiotic chromosome segregationGO:0045132190.335
Yeast
chromatin organizationGO:00063252060.316
regulation of cellular amine metabolic processGO:0033238200.294
negative regulation of cell cycleGO:00457861230.287
Human
male sex differentiationGO:00466611090.282
male gamete generationGO:00482322850.278
cellular amine metabolic processGO:0044106440.278
regulation of nuclear cell cycle dna replicationGO:003326220.245
nucleoside monophosphate metabolic processGO:0009123850.243
response to radiationGO:00093141650.226
regulation of chromosome organizationGO:0033044830.224
cell cycle checkpointGO:0000075470.212
chromatin silencingGO:0006342150.209
dna dependent dna replicationGO:0006261240.204
Human
genitalia developmentGO:0048806370.201
positive regulation of chromosome organizationGO:2001252330.198
cellular amino acid metabolic processGO:00065201030.196
regulation of histone modificationGO:0031056560.194
regulation of protein acetylationGO:1901983220.193
response to light stimulusGO:00094161350.184
meiosis iGO:0007127600.172
Yeast
regulation of transcription by chromatin organizationGO:003440100.170
negative regulation of cellular amino acid metabolic processGO:004576300.163
protein dna complex subunit organizationGO:0071824280.155
positive regulation of cellular amine metabolic processGO:003324050.147
chromosome segregationGO:0007059480.146
Human Yeast Zebrafish
regulation of mitotic cell cycleGO:00073461260.142
glycerophospholipid metabolic processGO:0006650710.139
spermatid differentiationGO:00485151150.138
cell maturationGO:00484691270.137
regulation of mitotic cell cycle phase transitionGO:1901990730.136
regulation of cellular ketone metabolic processGO:0010565660.136
regulation of peptidyl lysine acetylationGO:2000756220.135
negative regulation of cell cycle processGO:0010948690.131
Human
peptidyl amino acid modificationGO:00181933360.129
purine nucleoside triphosphate metabolic processGO:00091442260.126
sister chromatid segregationGO:0000819200.124
Yeast Zebrafish
regulation of cell cycle processGO:00105641600.122
Human
negative regulation of chromosome organizationGO:2001251300.119
stem cell developmentGO:00488642190.117
dna packagingGO:0006323300.115
meiotic sister chromatid cohesionGO:005117760.111
Yeast
response to uvGO:0009411440.110
protein acylationGO:0043543640.106
endocytosisGO:00068971680.102
membrane depolarizationGO:0051899640.100
dna recombinationGO:0006310920.095
Yeast
regulation of organelle organizationGO:00330432890.094
internal peptidyl lysine acetylationGO:0018393420.093
negative regulation of cellular amine metabolic processGO:003323910.093
mitotic cell cycle checkpointGO:0007093310.090
mitotic nuclear divisionGO:0007067480.088
Yeast Zebrafish
dna methylation involved in gamete generationGO:0043046150.087
ribose phosphate metabolic processGO:00196932910.086
regulation of histone acetylationGO:0035065190.085
purine ribonucleoside triphosphate metabolic processGO:00092052200.083
signal transduction by p53 class mediatorGO:0072331510.081
nucleotide metabolic processGO:00091173320.080
meiotic sister chromatid segregationGO:004514460.080
Yeast
amine metabolic processGO:0009308450.080
negative regulation of mitotic cell cycleGO:0045930580.077
ribonucleoside triphosphate metabolic processGO:00091992200.077
histone acetylationGO:0016573410.074
purine nucleotide catabolic processGO:00061952110.073
ribonucleoside monophosphate metabolic processGO:0009161800.071
negative regulation of mitotic cell cycle phase transitionGO:1901991450.068
peptidyl lysine acetylationGO:0018394450.067
replication fork processingGO:003129710.065
apoptotic signaling pathwayGO:00971903060.065
glycosyl compound metabolic processGO:19016572460.063
regulation of histone methylationGO:0031060300.063
neuron projection guidanceGO:00974851410.061
nucleobase containing small molecule metabolic processGO:00550863520.060
protein localization to organelleGO:00333651850.058
development of primary male sexual characteristicsGO:0046546880.058
male meiosisGO:0007140370.058
ribonucleotide catabolic processGO:00092612080.058
fertilizationGO:00095661270.056
adult behaviorGO:00305341350.054
cellular biogenic amine metabolic processGO:0006576280.053
neuron apoptotic processGO:00514021420.052
cellular respirationGO:0045333380.050
alcohol metabolic processGO:00060661160.049
purine ribonucleoside monophosphate metabolic processGO:0009167800.049
negative regulation of cell cycle phase transitionGO:1901988480.049
negative regulation of cellular component organizationGO:00511291940.048
axon guidanceGO:00074111410.048
intraspecies interaction between organismsGO:0051703210.047
glial cell migrationGO:000834770.046
regulation of chromatin silencingGO:003193520.046
axonogenesisGO:00074092740.044
positive regulation of cellular component biogenesisGO:0044089940.044
telomere maintenanceGO:0000723190.043
ribonucleoside metabolic processGO:00091192450.043
regulation of neuron deathGO:19012141340.042
glutamine metabolic processGO:000654180.042
nuclear dna replicationGO:003326030.042
internal protein amino acid acetylationGO:0006475420.041
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.041
histone lysine methylationGO:0034968500.041
neuromuscular process controlling postureGO:0050884140.041
receptor mediated endocytosisGO:0006898510.041
positive regulation of histone methylationGO:0031062160.041
blastocyst developmentGO:0001824800.041
visual learningGO:0008542440.040
negative regulation of chromatin modificationGO:1903309190.040
mapk cascadeGO:00001652810.040
male gonad developmentGO:0008584880.040
visual behaviorGO:0007632450.039
positive regulation of organelle organizationGO:00106381280.038
organophosphate catabolic processGO:00464342320.038
regulation of membrane potentialGO:00423911920.036
anatomical structure homeostasisGO:00602491450.035
chemotaxisGO:00069352470.034
epithelial cell developmentGO:00020641590.034
regulation of gene expression by genetic imprintingGO:0006349150.034
nitrogen compound transportGO:00717052710.034
cell type specific apoptotic processGO:00972852680.033
organelle localizationGO:00516401790.033
regulation of cell cycle phase transitionGO:1901987770.033
response to oxygen levelsGO:0070482620.033
positive regulation of chromatin modificationGO:1903310280.031
organic hydroxy compound metabolic processGO:19016152030.031
positive regulation of nuclear cell cycle dna replicationGO:001057110.030
organic cyclic compound catabolic processGO:19013612950.030
dna damage response signal transduction by p53 class mediatorGO:0030330190.030
purine nucleoside triphosphate catabolic processGO:00091462030.029
positive regulation of cell cycle processGO:0090068610.029
cerebellum developmentGO:0021549770.029
purine ribonucleotide metabolic processGO:00091502900.029
glutamine family amino acid metabolic processGO:0009064150.028
chromatin remodelingGO:0006338320.028
learningGO:0007612980.027
positive regulation of histone modificationGO:0031058280.027
negative regulation of neuron deathGO:1901215980.027
dna alkylationGO:0006305430.027
oxidation reduction processGO:00551143420.026
locomotory behaviorGO:00076261950.026
cellular response to organonitrogen compoundGO:00714171450.026
response to decreased oxygen levelsGO:0036293590.026
forebrain developmentGO:00309003020.025
negative regulation of protein modification processGO:00314001630.025
aromatic compound catabolic processGO:00194392860.025
signal transduction in response to dna damageGO:0042770210.024
social behaviorGO:0035176210.023
heterochromatin assemblyGO:003150720.022
purine ribonucleoside triphosphate catabolic processGO:00092071990.022
double strand break repair via homologous recombinationGO:0000724210.022
Yeast
nucleoside triphosphate catabolic processGO:00091432050.022
regulation of respiratory system processGO:0044065130.021
defense response to other organismGO:00985421970.021
nucleoside phosphate catabolic processGO:19012922220.021
purine containing compound metabolic processGO:00725213110.021
response to hypoxiaGO:0001666580.021
glycerolipid metabolic processGO:00464861220.021
microtubule based processGO:00070172360.021
Human
intra s dna damage checkpointGO:003157340.021
positive regulation of homeostatic processGO:0032846640.020
nucleoside metabolic processGO:00091162460.020
regulation of respiratory gaseous exchange by neurological system processGO:0002087120.019
ribonucleoside monophosphate catabolic processGO:0009158570.019
nucleoside phosphate metabolic processGO:00067533380.019
phospholipid metabolic processGO:0006644870.019
neuron deathGO:00709971540.019
positive regulation of synapse assemblyGO:0051965180.019
purine nucleotide metabolic processGO:00061633020.019
establishment of organelle localizationGO:00516561220.018
heterochromatin organization involved in chromatin silencingGO:007086810.018
microtubule nucleationGO:000702020.018
chromatin assemblyGO:0031497130.018
carbohydrate derivative catabolic processGO:19011362310.017
nucleic acid phosphodiester bond hydrolysisGO:0090305490.017
rna processingGO:00063961050.017
regulation of respiratory gaseous exchangeGO:0043576180.017
nucleoside triphosphate metabolic processGO:00091412300.017
ribonucleoside catabolic processGO:00424542060.016
cognitionGO:00508901490.016
histone h3 k4 methylationGO:0051568230.016
regulation of bindingGO:00510981110.016
regulation of cytoplasmic transportGO:19036491120.016
purine ribonucleoside monophosphate catabolic processGO:0009169570.016
regulation of cellular component biogenesisGO:00440871810.016
cellular lipid metabolic processGO:00442553230.016
adult locomotory behaviorGO:0008344910.016
germ cell developmentGO:00072811850.016
neuromuscular processGO:0050905990.015
cellular macromolecule catabolic processGO:00442652060.015
neurological system process involved in regulation of systemic arterial blood pressureGO:0001976180.015
purine nucleoside metabolic processGO:00422782410.015
multicellular organism growthGO:00352641610.015
histone h3 k9 dimethylationGO:003612340.015
positive regulation of cellular amino acid metabolic processGO:004576430.015
regulation of intracellular transportGO:00323861590.015
nucleotide catabolic processGO:00091662170.015
lymphocyte differentiationGO:00300982420.014
protein modification by small protein conjugation or removalGO:00706472070.014
negative regulation of cellular protein metabolic processGO:00322692470.014
regulation of neuron projection developmentGO:00109751690.014
spermatid developmentGO:00072861080.014
heterocycle catabolic processGO:00467002800.014
mitotic chromosome condensationGO:000707610.014
positive regulation of bindingGO:0051099490.014
protein modification by small protein removalGO:0070646210.014
negative regulation of synapse assemblyGO:005196430.014
somatic cell dna recombinationGO:0016444510.014
respiratory gaseous exchangeGO:0007585430.014
ribonucleotide metabolic processGO:00092592910.013
ribonucleoside triphosphate catabolic processGO:00092031990.013
leukocyte differentiationGO:00025213420.013
regulation of dna dependent dna replicationGO:009032980.013
Human
purine nucleoside monophosphate metabolic processGO:0009126810.013
intracellular mrna localizationGO:000829840.013
chromatin mediated maintenance of transcriptionGO:004809620.013
purine nucleoside catabolic processGO:00061522050.013
cellular response to inorganic substanceGO:0071241370.013
regulation of synaptic growth at neuromuscular junctionGO:000858240.013
positive regulation of nervous system developmentGO:00519622210.012
phosphatidylcholine metabolic processGO:0046470130.012
generation of precursor metabolites and energyGO:00060911030.012
negative regulation of cell proliferationGO:00082852960.012
cellular response to organic cyclic compoundGO:0071407870.012
insulin receptor signaling pathwayGO:0008286490.012
cellular response to hormone stimulusGO:00328701500.012
dna templated transcriptional preinitiation complex assemblyGO:007089740.012
negative regulation of neuron apoptotic processGO:0043524920.012
atp metabolic processGO:0046034750.012
positive regulation of protein phosphorylationGO:00019342420.012
catecholamine secretionGO:0050432150.012
nuclear transportGO:00511691390.011
synapse assemblyGO:0007416560.011
negative regulation of histone acetylationGO:003506770.011
nucleosome assemblyGO:000633470.011
long term synaptic potentiationGO:0060291250.011
peptidyl lysine methylationGO:0018022290.011
protein maturationGO:00516041760.011
associative learningGO:0008306610.011
polyol metabolic processGO:0019751260.011
ncrna processingGO:0034470260.011
regionalizationGO:00030023370.011
nucleocytoplasmic transportGO:00069131390.011
cardiolipin metabolic processGO:003204830.011
regulation of protein targetingGO:1903533610.011
organic hydroxy compound transportGO:0015850930.011
protein targetingGO:00066051430.011
response to inorganic substanceGO:0010035960.011
establishment of protein localization to organelleGO:00725941180.011
regulation of cellular response to stressGO:00801351590.011
atp catabolic processGO:0006200550.011
rna interferenceGO:001624620.011
sensory perceptionGO:00076002450.011
mitotic recombinationGO:000631230.011
endomembrane system organizationGO:00102561470.010
negative regulation of cellular catabolic processGO:0031330470.010
carbohydrate metabolic processGO:00059752300.010
female gamete generationGO:0007292740.010
regulation of lymphocyte activationGO:00512492400.010
adaptive immune responseGO:00022501550.010
erk1 and erk2 cascadeGO:0070371770.010

Smc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cornelia de lange syndromeDOID:1172500.910
Human
developmental disorder of mental healthDOID:006003700.058
autism spectrum disorderDOID:006004100.058
pervasive developmental disorderDOID:006004000.058
disease of mental healthDOID:15000.058
central nervous system diseaseDOID:33100.038
disease of anatomical entityDOID:700.038
nervous system diseaseDOID:86300.038
autistic disorderDOID:1284900.036
neurodegenerative diseaseDOID:128900.026
physical disorderDOID:008001500.011