Mus musculus

0 known processes

Smc6

structural maintenance of chromosomes 6

(Aliases: Smc6l1,AU018782,SMC-6,2810489L22Rik,mKIAA4103,KIAA4103,AW742439,AA990493,3830418C19Rik,MGC96146)

Smc6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742070.408
meiotic nuclear divisionGO:00071261150.274
organic cyclic compound catabolic processGO:19013612950.247
mitotic cell cycleGO:00002781950.246
nucleoside triphosphate metabolic processGO:00091412300.197
organophosphate catabolic processGO:00464342320.191
purine ribonucleoside catabolic processGO:00461302050.187
purine ribonucleotide metabolic processGO:00091502900.169
organelle fissionGO:00482851700.158
dna repairGO:00062811070.149
nucleotide metabolic processGO:00091173320.147
purine nucleoside catabolic processGO:00061522050.143
ribose phosphate metabolic processGO:00196932910.135
nucleoside phosphate metabolic processGO:00067533380.131
ribonucleotide catabolic processGO:00092612080.129
nucleobase containing small molecule metabolic processGO:00550863520.125
male meiosisGO:0007140370.121
meiosis iGO:0007127600.120
ribonucleotide metabolic processGO:00092592910.119
stem cell developmentGO:00488642190.118
purine nucleoside triphosphate catabolic processGO:00091462030.114
nucleoside triphosphate catabolic processGO:00091432050.111
purine ribonucleoside metabolic processGO:00461282410.110
purine ribonucleotide catabolic processGO:00091542080.108
heterocycle catabolic processGO:00467002800.107
meiotic cell cycle processGO:1903046770.105
mitotic cell cycle processGO:19030471590.103
carbohydrate derivative catabolic processGO:19011362310.101
purine nucleoside triphosphate metabolic processGO:00091442260.100
microtubule cytoskeleton organizationGO:00002261570.099
chromosome segregationGO:0007059480.098
cellular nitrogen compound catabolic processGO:00442702800.093
organelle assemblyGO:00709251770.090
regulation of cell cycle processGO:00105641600.090
glycosyl compound metabolic processGO:19016572460.089
protein modification by small protein conjugationGO:00324461870.088
microtubule organizing center organizationGO:0031023280.087
ribonucleoside triphosphate metabolic processGO:00091992200.087
heterochromatin organizationGO:007082840.085
cell divisionGO:00513011200.084
nucleoside catabolic processGO:00091642060.082
regulation of mitotic cell cycleGO:00073461260.080
purine ribonucleoside triphosphate metabolic processGO:00092052200.078
negative regulation of cell cycleGO:00457861230.078
positive regulation of gtpase activityGO:0043547850.075
nucleoside phosphate catabolic processGO:19012922220.075
ras protein signal transductionGO:0007265770.071
aromatic compound catabolic processGO:00194392860.068
glycosyl compound catabolic processGO:19016582060.068
purine nucleoside metabolic processGO:00422782410.068
purine nucleotide catabolic processGO:00061952110.068
microtubule based processGO:00070172360.065
ribonucleoside catabolic processGO:00424542060.065
protein localization to organelleGO:00333651850.061
organonitrogen compound catabolic processGO:19015652640.061
purine nucleotide metabolic processGO:00061633020.061
regulation of cell cycleGO:00517262810.061
cellular ketone metabolic processGO:0042180840.059
cellular macromolecule catabolic processGO:00442652060.059
positive regulation of apoptotic processGO:00430652170.058
apoptotic signaling pathwayGO:00971903060.057
purine containing compound catabolic processGO:00725232130.055
positive regulation of cell cycle processGO:0090068610.054
negative regulation of protein metabolic processGO:00512482820.052
ribonucleoside metabolic processGO:00091192450.051
dna metabolic processGO:00062593030.051
purine ribonucleoside triphosphate catabolic processGO:00092071990.050
protein maturationGO:00516041760.050
regulation of transcription by chromatin organizationGO:003440100.050
positive regulation of cell deathGO:00109422240.048
neural tube developmentGO:00219151600.047
response to radiationGO:00093141650.047
purine containing compound metabolic processGO:00725213110.046
development of primary sexual characteristicsGO:00451371430.046
ribonucleoside monophosphate metabolic processGO:0009161800.045
nucleotide catabolic processGO:00091662170.045
negative regulation of cell cycle phase transitionGO:1901988480.045
forebrain developmentGO:00309003020.044
leukocyte differentiationGO:00025213420.044
spermatogenesisGO:00072832840.044
regulation of chromosome organizationGO:0033044830.043
meiotic cell cycleGO:00513211220.043
dna dependent dna replication maintenance of fidelityGO:004500530.041
g1 s transition of mitotic cell cycleGO:0000082570.041
centrosome organizationGO:0051297260.041
regulation of neuron projection developmentGO:00109751690.040
protein acylationGO:0043543640.040
protein modification by small protein conjugation or removalGO:00706472070.040
ribonucleoside triphosphate catabolic processGO:00092031990.039
regulation of establishment of protein localizationGO:00702011810.039
regulation of organelle organizationGO:00330432890.039
spindle assembly involved in female meiosisGO:000705630.039
dna dependent dna replicationGO:0006261240.037
histone modificationGO:00165701590.037
negative regulation of dna replicationGO:000815640.036
regulation of apoptotic signaling pathwayGO:20012331970.036
negative regulation of dna dependent dna replicationGO:200010410.035
nucleoside monophosphate metabolic processGO:0009123850.034
positive regulation of organelle organizationGO:00106381280.034
chromatin organizationGO:00063252060.034
dna replicationGO:0006260520.033
regulation of cell projection organizationGO:00313442060.033
epithelial tube formationGO:00721751300.033
atp catabolic processGO:0006200550.032
mapk cascadeGO:00001652810.032
protein ubiquitinationGO:00165671710.032
blastocyst developmentGO:0001824800.032
lateral inhibitionGO:004633110.031
regulation of nucleoside metabolic processGO:00091181300.031
blood vessel morphogenesisGO:00485142850.031
regulation of nucleotide metabolic processGO:00061401690.031
regulation of cell cycle phase transitionGO:1901987770.030
rho protein signal transductionGO:0007266320.030
cellular amine metabolic processGO:0044106440.030
guanosine containing compound metabolic processGO:19010681440.030
cellular protein catabolic processGO:00442571550.029
chromosome organization involved in meiosisGO:0070192390.029
camera type eye developmentGO:00430102660.029
positive regulation of programmed cell deathGO:00430682180.029
regulation of neuron apoptotic processGO:00435231220.029
stem cell maintenanceGO:00198271300.029
cellular amino acid metabolic processGO:00065201030.028
nucleoside metabolic processGO:00091162460.028
regulation of transferase activityGO:00513382630.027
rna processingGO:00063961050.027
mitotic sister chromatid segregationGO:0000070140.027
negative regulation of cell proliferationGO:00082852960.027
small gtpase mediated signal transductionGO:0007264970.027
gtp catabolic processGO:00061841430.027
regulation of purine nucleotide metabolic processGO:19005421690.027
negative regulation of cellular component organizationGO:00511291940.026
telomere maintenanceGO:0000723190.026
nucleus localizationGO:0051647200.026
regulation of neuron differentiationGO:00456642810.026
nuclear divisionGO:00002801580.026
regulation of cellular amino acid metabolic processGO:000652150.026
maintenance of locationGO:0051235890.026
spindle assembly involved in meiosisGO:009030640.026
regulation of kinase activityGO:00435492490.025
neural precursor cell proliferationGO:00613511210.025
mitotic nuclear divisionGO:0007067480.025
response to growth factorGO:00708481980.025
chromatin silencing at rdnaGO:000018330.025
actin mediated cell contractionGO:0070252150.025
positive regulation of protein modification processGO:00314012990.025
macromolecule catabolic processGO:00090572810.025
lymphocyte differentiationGO:00300982420.024
organelle localizationGO:00516401790.024
gtp metabolic processGO:00460391440.024
homeostasis of number of cellsGO:00488722100.024
cytoplasmic transportGO:00164822340.024
regulation of cellular response to stressGO:00801351590.023
regulation of cellular component biogenesisGO:00440871810.023
regulation of mapk cascadeGO:00434082480.023
guanosine containing compound catabolic processGO:19010691440.023
circulatory system processGO:00030131970.023
response to organonitrogen compoundGO:00102432460.023
epithelial tube morphogenesisGO:00605623030.022
regulation of intracellular transportGO:00323861590.022
positive regulation of cellular component biogenesisGO:0044089940.022
compound eye developmentGO:004874910.022
gland developmentGO:00487323300.022
dna recombinationGO:0006310920.022
oocyte axis specificationGO:000730920.021
positive regulation of cytoskeleton organizationGO:0051495490.021
neural tube formationGO:00018411080.021
ossificationGO:00015032160.021
regulation of protein transportGO:00512231630.021
response to organic cyclic compoundGO:00140701980.021
negative regulation of mitotic cell cycleGO:0045930580.021
regulation of cell activationGO:00508652890.021
double strand break repairGO:0006302480.021
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.021
negative regulation of molecular functionGO:00440922580.021
cell type specific apoptotic processGO:00972852680.021
negative regulation of mitotic cell cycle phase transitionGO:1901991450.021
protein localization to nucleusGO:00345041210.021
methylationGO:00322591340.020
protein catabolic processGO:00301632210.020
morphogenesis of embryonic epitheliumGO:00163311590.020
negative regulation of cell cycle processGO:0010948690.020
organic hydroxy compound metabolic processGO:19016152030.020
gonad developmentGO:00084061410.020
rna splicingGO:0008380540.019
negative regulation of chromatin silencingGO:003193610.019
male gamete generationGO:00482322850.019
regulation of protein kinase activityGO:00458592320.019
regulation of membrane potentialGO:00423911920.019
regulation of secretionGO:00510462740.019
positive regulation of apoptotic signaling pathwayGO:2001235950.019
dna packagingGO:0006323300.019
anatomical structure homeostasisGO:00602491450.019
response to light stimulusGO:00094161350.019
regulation of gtp catabolic processGO:00331241130.019
regulation of cellular amine metabolic processGO:0033238200.019
posttranscriptional regulation of gene expressionGO:00106081550.019
regulation of cellular catabolic processGO:00313292420.018
germ cell developmentGO:00072811850.018
regulation of cell migrationGO:00303342190.018
myeloid cell differentiationGO:00300992330.018
cellular response to abiotic stimulusGO:0071214560.018
spindle organizationGO:0007051280.018
purine ribonucleoside monophosphate metabolic processGO:0009167800.018
regulation of cell motilityGO:20001452360.018
regulation of chromatin silencingGO:003193520.018
axonogenesisGO:00074092740.018
telomere cappingGO:001623340.018
positive regulation of nucleotide metabolic processGO:00459811140.018
regulation of response to woundingGO:19030341890.018
adult behaviorGO:00305341350.018
chromatin modificationGO:00165681870.018
positive regulation of cell cycleGO:0045787920.018
regulation of protein localizationGO:00328802310.017
positive regulation of protein phosphorylationGO:00019342420.017
negative regulation of chromosome organizationGO:2001251300.017
cellular response to lipidGO:00713961450.017
multi organism reproductive behaviorGO:0044705290.017
actin filament based movementGO:0030048230.017
protein importGO:00170381010.017
tube formationGO:00351481400.017
regulation of cell morphogenesis involved in differentiationGO:00107691510.017
atp metabolic processGO:0046034750.017
positive regulation of protein kinase activityGO:00458601440.017
nucleic acid phosphodiester bond hydrolysisGO:0090305490.017
leukocyte homeostasisGO:0001776790.017
retina development in camera type eyeGO:00600411190.017
multi organism behaviorGO:0051705620.016
tube closureGO:0060606910.016
negative regulation of gene expression epigeneticGO:0045814150.016
regulation of chromatin organizationGO:1902275570.016
cytokine productionGO:00018163190.016
protein dna complex subunit organizationGO:0071824280.016
regulation of neuron deathGO:19012141340.016
mitotic cell cycle checkpointGO:0007093310.016
regulation of vesicle mediated transportGO:00606271390.016
nuclear importGO:0051170950.016
immune effector processGO:00022523210.016
positive regulation of hydrolase activityGO:00513451480.015
amine metabolic processGO:0009308450.015
neural tube closureGO:0001843900.015
regulation of mitotic cell cycle phase transitionGO:1901990730.015
negative regulation of cellular protein metabolic processGO:00322692470.015
positive regulation of kinase activityGO:00336741550.015
negative regulation of protein modification processGO:00314001630.015
proteolysis involved in cellular protein catabolic processGO:00516031470.015
skin developmentGO:00435882200.015
skeletal system developmentGO:00015013560.015
dendrite developmentGO:00163581150.015
male meiosis iGO:0007141160.015
multicellular organism growthGO:00352641610.015
regulation of cellular ketone metabolic processGO:0010565660.015
regulation of circadian rhythmGO:0042752580.015
regulation of system processGO:00440572000.015
ubiquitin dependent protein catabolic processGO:00065111290.014
respiratory system developmentGO:00605411900.014
neuron deathGO:00709971540.014
regulation of response to dna damage stimulusGO:2001020340.014
regulation of protein complex assemblyGO:0043254830.014
angiogenesisGO:00015252010.014
sister chromatid segregationGO:0000819200.014
muscle tissue developmentGO:00605373080.014
developmental growth involved in morphogenesisGO:00605601380.014
spermatid differentiationGO:00485151150.014
intrinsic apoptotic signaling pathwayGO:00971931320.014
negative regulation of protein processingGO:0010955790.014
modification dependent macromolecule catabolic processGO:00436321330.014
signal transduction involved in mitotic dna integrity checkpointGO:190240330.014
cell cycle checkpointGO:0000075470.014
heterochromatin organization involved in chromatin silencingGO:007086810.014
purine nucleoside monophosphate metabolic processGO:0009126810.014
regulation of nuclear divisionGO:0051783560.014
branching morphogenesis of an epithelial tubeGO:00487541590.013
limb developmentGO:00601731660.013
negative regulation of immune system processGO:00026832090.013
cellular component assembly involved in morphogenesisGO:00109271390.013
regulation of dna endoreduplicationGO:003287530.013
stem cell differentiationGO:00488632680.013
meiotic chromosome segregationGO:0045132190.013
negative regulation of neuron differentiationGO:00456651010.013
positive regulation of nucleoside metabolic processGO:0045979910.013
cellular response to organonitrogen compoundGO:00714171450.013
regulation of chromatin modificationGO:1903308570.013
positive regulation of ras gtpase activityGO:0032320650.013
protein targetingGO:00066051430.013
protein processingGO:00164851630.013
regulation of nucleotide catabolic processGO:00308111220.013
negative regulation of cell developmentGO:00107211690.013
regulation of microtubule based processGO:0032886520.013
multi multicellular organism processGO:00447061090.013
positive regulation of cellular amino acid metabolic processGO:004576430.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
ear developmentGO:00435832000.013
mitotic sister chromatid cohesionGO:000706410.013
termination of rna polymerase i transcriptionGO:000636320.013
response to uvGO:0009411440.013
regulation of intracellular protein transportGO:0033157820.013
regulation of nucleocytoplasmic transportGO:0046822730.013
positive regulation of bindingGO:0051099490.013
leukocyte apoptotic processGO:0071887710.013
positive regulation of protein localization to nucleusGO:1900182300.013
cellular response to gamma radiationGO:007148040.013
regulation of b cell activationGO:0050864810.013
b cell activationGO:00421131610.012
regulation of protein maturationGO:1903317960.012
second messenger mediated signalingGO:0019932730.012
establishment of protein localization to organelleGO:00725941180.012
skeletal muscle organ developmentGO:00605381630.012
negative regulation of intracellular signal transductionGO:19025321670.012
negative regulation of proteolysisGO:0045861740.012
rna interferenceGO:001624620.012
skeletal system morphogenesisGO:00487052030.012
striated muscle cell developmentGO:00550021250.012
membrane organizationGO:00610242450.012
cellular response to organic cyclic compoundGO:0071407870.012
neuron migrationGO:00017641220.012
axon guidanceGO:00074111410.012
epithelial cell developmentGO:00020641590.012
centrosome duplicationGO:0051298160.012
stem cell proliferationGO:00720891170.012
regulation of bindingGO:00510981110.012
female meiotic divisionGO:0007143210.012
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.012
ribonucleoside monophosphate catabolic processGO:0009158570.012
protein modification by small protein removalGO:0070646210.012
apical constrictionGO:000338340.012
meiotic sister chromatid segregationGO:004514460.012
regulation of cell shapeGO:0008360390.012
regulation of hydrolase activityGO:00513362460.012
positive regulation of homeostatic processGO:0032846640.012
positive regulation of intracellular protein transportGO:0090316420.012
regulation of protein processingGO:0070613960.012
adaptive immune responseGO:00022501550.011
kinetochore organizationGO:005138320.011
blood circulationGO:00080151950.011
muscle cell differentiationGO:00426922610.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
chemotaxisGO:00069352470.011
gastrulationGO:00073691160.011
cell matrix adhesionGO:0007160680.011
oogenesisGO:0048477560.011
primary neural tube formationGO:0014020950.011
organophosphate biosynthetic processGO:00904071220.011
regulation of microtubule cytoskeleton organizationGO:0070507370.011
regulation of wnt signaling pathwayGO:00301111230.011
mitotic cytokinesisGO:000028140.011
cell maturationGO:00484691270.011
covalent chromatin modificationGO:00165691630.011
mitotic chromosome condensationGO:000707610.011
negative regulation of phosphorylationGO:00423261660.011
intracellular protein transportGO:00068862040.011
negative regulation of neuron deathGO:1901215980.011
purine nucleoside monophosphate catabolic processGO:0009128580.011
cellular chemical homeostasisGO:00550822150.011
nuclear dna replicationGO:003326030.011
dna templated transcription initiationGO:0006352130.011
genetic imprintingGO:0071514270.010
regulation of protein localization to nucleusGO:1900180600.010
regulation of defense responseGO:00313472330.010
heart processGO:0003015940.010
regulation of planar cell polarity pathway involved in axis elongationGO:200004030.010
maintenance of protein location in nucleusGO:005145720.010
calcium ion transportGO:00068161590.010
regulation of embryonic developmentGO:0045995710.010
modification dependent protein catabolic processGO:00199411330.010
neuron apoptotic processGO:00514021420.010
epidermis developmentGO:00085441870.010
chromatin silencingGO:0006342150.010
definitive hemopoiesisGO:0060216200.010
maintenance of location in cellGO:0051651240.010
extrinsic apoptotic signaling pathwayGO:00971911260.010
wound healingGO:00420601570.010
maintenance of protein location in cellGO:0032507200.010
positive regulation of protein transportGO:0051222930.010
embryonic epithelial tube formationGO:00018381300.010
bone developmentGO:00603481200.010
negative regulation of b cell activationGO:0050869270.010

Smc6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.029
disease of anatomical entityDOID:700.029
breast cancerDOID:161200.026
organ system cancerDOID:005068600.026
thoracic cancerDOID:509300.026
disease of cellular proliferationDOID:1456600.026
cancerDOID:16200.026
sensory system diseaseDOID:005015500.023
eye and adnexa diseaseDOID:149200.022
eye diseaseDOID:561400.022
endocrine gland cancerDOID:17000.014
central nervous system diseaseDOID:33100.011
neurodegenerative diseaseDOID:128900.010