Mus musculus

111 known processes

Insig1

insulin induced gene 1

(Aliases: 1810013C12Rik,Insig-1)

Insig1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lipid biosynthetic processGO:00086101790.371
cellular alcohol biosynthetic processGO:004410830.316
small molecule biosynthetic processGO:00442831320.165
alcohol metabolic processGO:00060661160.142
cellular lipid metabolic processGO:00442553230.141
oxidation reduction processGO:00551143420.138
cellular amino acid metabolic processGO:00065201030.126
sterol metabolic processGO:0016125580.118
cellular alcohol metabolic processGO:004410730.097
organic hydroxy compound metabolic processGO:19016152030.089
regulation of cellular amino acid metabolic processGO:000652150.074
cellular amine metabolic processGO:0044106440.073
amine metabolic processGO:0009308450.066
cholesterol biosynthetic processGO:0006695150.065
alcohol biosynthetic processGO:0046165430.064
fat cell differentiationGO:00454441600.059
steroid metabolic processGO:00082021190.058
regulation of cellular ketone metabolic processGO:0010565660.055
cholesterol metabolic processGO:0008203560.055
organonitrogen compound biosynthetic processGO:19015661920.048
negative regulation of molecular functionGO:00440922580.042
response to organonitrogen compoundGO:00102432460.040
regulation of cellular amine metabolic processGO:0033238200.039
sulfur compound metabolic processGO:00067901000.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
transmembrane transportGO:00550854120.034
organic acid biosynthetic processGO:0016053860.033
glycerolipid metabolic processGO:00464861220.032
inflammatory responseGO:00069542440.032
response to radiationGO:00093141650.032
response to organic cyclic compoundGO:00140701980.032
regulation of membrane potentialGO:00423911920.031
negative regulation of protein metabolic processGO:00512482820.031
nitrogen compound transportGO:00717052710.030
negative regulation of cellular protein metabolic processGO:00322692470.030
leukocyte differentiationGO:00025213420.029
cellular ketone metabolic processGO:0042180840.029
monocarboxylic acid metabolic processGO:00327871910.029
regulation of secretionGO:00510462740.028
positive regulation of cellular amine metabolic processGO:003324050.028
spermatogenesisGO:00072832840.028
purine ribonucleotide metabolic processGO:00091502900.028
cellular homeostasisGO:00197252400.028
cation transportGO:00068123990.027
protein maturationGO:00516041760.027
male gamete generationGO:00482322850.026
striated muscle tissue developmentGO:00147062930.026
peptidyl amino acid modificationGO:00181933360.026
positive regulation of protein modification processGO:00314012990.026
purine nucleotide metabolic processGO:00061633020.026
organic anion transportGO:00157111370.026
sterol biosynthetic processGO:0016126170.026
ion transmembrane transportGO:00342203610.026
nucleobase containing small molecule metabolic processGO:00550863520.025
camera type eye developmentGO:00430102660.025
microtubule based processGO:00070172360.025
aromatic compound catabolic processGO:00194392860.024
organic hydroxy compound biosynthetic processGO:1901617770.024
regulation of organelle organizationGO:00330432890.024
Human
forebrain developmentGO:00309003020.024
organic cyclic compound catabolic processGO:19013612950.023
response to extracellular stimulusGO:00099911270.023
regulation of hormone levelsGO:00108172110.023
regulation of hydrolase activityGO:00513362460.023
cofactor metabolic processGO:0051186800.022
carbohydrate derivative biosynthetic processGO:19011371830.022
gland developmentGO:00487323300.022
protein processingGO:00164851630.022
immune effector processGO:00022523210.022
sensory perceptionGO:00076002450.022
multicellular organismal signalingGO:0035637910.022
response to light stimulusGO:00094161350.022
multicellular organism growthGO:00352641610.022
macromolecule catabolic processGO:00090572810.022
cellular response to lipidGO:00713961450.022
sensory organ morphogenesisGO:00905962420.022
regulation of system processGO:00440572000.022
mitochondrion organizationGO:00070051340.022
cation transmembrane transportGO:00986552660.021
alpha amino acid metabolic processGO:1901605590.021
innate immune responseGO:00450871570.021
cation homeostasisGO:00550802120.021
germ cell developmentGO:00072811850.021
blood circulationGO:00080151950.020
inorganic cation transmembrane transportGO:00986622070.020
dna metabolic processGO:00062593030.020
positive regulation of cell developmentGO:00107202370.020
cell type specific apoptotic processGO:00972852680.020
neutral lipid metabolic processGO:0006638570.019
ribose phosphate metabolic processGO:00196932910.019
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.019
muscle tissue developmentGO:00605373080.019
ossificationGO:00015032160.019
cellular chemical homeostasisGO:00550822150.019
cytokine productionGO:00018163190.019
chromatin organizationGO:00063252060.019
nucleoside phosphate metabolic processGO:00067533380.019
cytoplasmic transportGO:00164822340.019
Human
positive regulation of programmed cell deathGO:00430682180.019
t cell activationGO:00421102890.019
divalent metal ion transportGO:00708381720.019
metal ion homeostasisGO:00550651890.019
circulatory system processGO:00030131970.019
monocarboxylic acid biosynthetic processGO:0072330610.019
action potentialGO:0001508780.018
purine ribonucleoside metabolic processGO:00461282410.018
ribonucleotide metabolic processGO:00092592910.018
anion transportGO:00068201770.018
monosaccharide metabolic processGO:00059961060.018
glycosyl compound metabolic processGO:19016572460.018
regulation of secretion by cellGO:19035302490.018
cellular ion homeostasisGO:00068731650.018
purine containing compound biosynthetic processGO:0072522700.018
membrane lipid metabolic processGO:0006643530.018
apoptotic signaling pathwayGO:00971903060.018
embryonic organ morphogenesisGO:00485622760.017
cellular nitrogen compound catabolic processGO:00442702800.017
cellular response to hormone stimulusGO:00328701500.017
dephosphorylationGO:00163111290.017
negative regulation of intracellular signal transductionGO:19025321670.017
coenzyme biosynthetic processGO:0009108230.017
regulation of ion transportGO:00432692150.017
negative regulation of cellular component organizationGO:00511291940.017
Human
locomotory behaviorGO:00076261950.017
regulation of apoptotic signaling pathwayGO:20012331970.017
muscle system processGO:00030121410.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.017
steroid biosynthetic processGO:0006694470.017
cellular metal ion homeostasisGO:00068751510.017
response to acid chemicalGO:00011011110.017
response to oxidative stressGO:00069791230.017
regulation of transferase activityGO:00513382630.017
endomembrane system organizationGO:00102561470.017
respiratory system developmentGO:00605411900.017
transmission of nerve impulseGO:0019226760.017
homeostasis of number of cellsGO:00488722100.016
regulation of cytokine productionGO:00018172660.016
heterocycle catabolic processGO:00467002800.016
protein catabolic processGO:00301632210.016
ear developmentGO:00435832000.016
activation of immune responseGO:00022531380.016
cellular modified amino acid metabolic processGO:0006575630.016
regulation of cell cycleGO:00517262810.016
fatty acid metabolic processGO:00066311210.016
reactive oxygen species metabolic processGO:0072593840.016
neuronal action potentialGO:0019228540.016
synaptic transmissionGO:00072683290.016
carboxylic acid transportGO:00469421000.016
nuclear divisionGO:00002801580.016
nucleotide metabolic processGO:00091173320.016
lipid catabolic processGO:0016042690.016
carboxylic acid catabolic processGO:0046395510.016
response to nutrient levelsGO:00316671090.016
organelle fissionGO:00482851700.016
response to molecule of bacterial originGO:00022371430.016
carboxylic acid biosynthetic processGO:0046394860.016
regulation of proteolysisGO:00301621640.015
membrane organizationGO:00610242450.015
Human
regulation of homeostatic processGO:00328441820.015
regulation of body fluid levelsGO:00508781620.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
meiotic cell cycleGO:00513211220.015
cellular response to external stimulusGO:0071496880.015
cellular response to acid chemicalGO:0071229680.015
cofactor transportGO:005118140.015
mapk cascadeGO:00001652810.015
coenzyme metabolic processGO:0006732520.015
myeloid cell differentiationGO:00300992330.015
cellular response to growth factor stimulusGO:00713631970.015
regulation of cell activationGO:00508652890.015
cellular carbohydrate metabolic processGO:00442621190.015
organic acid catabolic processGO:0016054510.015
calcium ion transportGO:00068161590.015
amide transportGO:00428861380.015
sequestering of calcium ionGO:0051208180.015
long chain fatty acid importGO:004453920.015
maintenance of locationGO:0051235890.015
purine nucleoside metabolic processGO:00422782410.014
skeletal system developmentGO:00015013560.014
regulation of defense responseGO:00313472330.014
posttranscriptional regulation of gene expressionGO:00106081550.014
regulation of mapk cascadeGO:00434082480.014
cellular macromolecule catabolic processGO:00442652060.014
regulation of kinase activityGO:00435492490.014
ribonucleoside metabolic processGO:00091192450.014
response to inorganic substanceGO:0010035960.014
actin cytoskeleton organizationGO:00300362200.014
inorganic ion transmembrane transportGO:00986602340.014
divalent inorganic cation transportGO:00725111780.014
regulation of lipid metabolic processGO:00192161180.014
spermatid differentiationGO:00485151150.014
blood vessel morphogenesisGO:00485142850.014
response to lipopolysaccharideGO:00324961280.014
cellular response to extracellular stimulusGO:0031668810.014
positive regulation of nervous system developmentGO:00519622210.014
small molecule catabolic processGO:0044282710.014
chromatin modificationGO:00165681870.014
compound eye developmentGO:004874910.014
reactive oxygen species biosynthetic processGO:190340980.014
intracellular protein transportGO:00068862040.014
myotube differentiationGO:00149021050.014
kidney developmentGO:00018222130.014
circadian rhythmGO:00076231140.014
organophosphate biosynthetic processGO:00904071220.014
negative regulation of protein modification processGO:00314001630.014
regulation of establishment of protein localizationGO:00702011810.014
negative regulation of apoptotic signaling pathwayGO:20012341040.013
rhythmic processGO:00485111740.013
organonitrogen compound catabolic processGO:19015652640.013
adult behaviorGO:00305341350.013
glutamate metabolic processGO:000653690.013
morphogenesis of embryonic epitheliumGO:00163311590.013
regulation of neuron differentiationGO:00456642810.013
glucose homeostasisGO:00425931280.013
liver developmentGO:0001889660.013
regulation of lymphocyte activationGO:00512492400.013
skeletal muscle organ developmentGO:00605381630.013
heart contractionGO:0060047930.013
response to peptideGO:19016521360.013
retrograde transport endosome to golgiGO:004214720.013
cellular amino acid biosynthetic processGO:0008652220.013
fat soluble vitamin biosynthetic processGO:004236240.013
positive regulation of secretionGO:00510471300.013
negative regulation of cellular amine metabolic processGO:003323910.013
lymphocyte differentiationGO:00300982420.013
negative regulation of lipid metabolic processGO:0045833300.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
negative regulation of hydrolase activityGO:0051346710.013
cellular response to organonitrogen compoundGO:00714171450.013
carbohydrate metabolic processGO:00059752300.013
ribonucleotide biosynthetic processGO:0009260590.013
organelle localizationGO:00516401790.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.013
regulation of protein maturationGO:1903317960.013
organophosphate catabolic processGO:00464342320.013
cellular divalent inorganic cation homeostasisGO:00725031270.013
regulation of intracellular transportGO:00323861590.013
Human
mitotic cell cycleGO:00002781950.013
nucleoside phosphate biosynthetic processGO:1901293790.013
energy derivation by oxidation of organic compoundsGO:0015980770.013
plasma membrane organizationGO:0007009900.013
muscle cell differentiationGO:00426922610.013
nucleotide catabolic processGO:00091662170.013
negative regulation of phosphorus metabolic processGO:00105631840.013
morphogenesis of a branching structureGO:00017632030.013
cellular biogenic amine metabolic processGO:0006576280.013
positive regulation of protein phosphorylationGO:00019342420.013
spermatid developmentGO:00072861080.013
purine containing compound metabolic processGO:00725213110.013
telencephalon developmentGO:00215371860.013
nucleoside phosphate catabolic processGO:19012922220.012
regulation of peptidase activityGO:0052547960.012
regulation of t cell activationGO:00508631700.012
epithelial cell proliferationGO:00506731740.012
negative regulation of cell proliferationGO:00082852960.012
hormone secretionGO:00468791280.012
regulation of reactive oxygen species biosynthetic processGO:190342620.012
peptide transportGO:00158331330.012
regulation of lipid catabolic processGO:0050994150.012
acylglycerol metabolic processGO:0006639550.012
protein modification by small protein conjugationGO:00324461870.012
carbohydrate derivative catabolic processGO:19011362310.012
regulation of leukocyte differentiationGO:19021051590.012
neuron deathGO:00709971540.012
multicellular organismal homeostasisGO:00488711640.012
regulation of protein localizationGO:00328802310.012
cell activation involved in immune responseGO:00022631260.012
connective tissue developmentGO:00614481790.012
leukocyte activation involved in immune responseGO:00023661260.012
regulation of protein serine threonine kinase activityGO:00719001570.012
developmental growth involved in morphogenesisGO:00605601380.012
regulation of neuron deathGO:19012141340.012
peptide metabolic processGO:0006518460.012
ribose phosphate biosynthetic processGO:0046390590.012
glycerophospholipid metabolic processGO:0006650710.012
detection of stimulusGO:0051606840.012
negative regulation of protein phosphorylationGO:00019331260.012
regulation of anatomical structure sizeGO:00900661780.012
response to insulinGO:00328681000.012
divalent inorganic cation homeostasisGO:00725071380.012
cellular amide metabolic processGO:0043603580.012
anatomical structure homeostasisGO:00602491450.012
leukocyte proliferationGO:00706611720.012
ribonucleoside triphosphate metabolic processGO:00091992200.012
organic acid transportGO:00158491010.012
glutathione metabolic processGO:0006749160.012
regulation of ion transmembrane transportGO:00347651190.012
ras protein signal transductionGO:0007265770.012
meiotic nuclear divisionGO:00071261150.012
positive regulation of cell deathGO:00109422240.012
peptidyl tyrosine modificationGO:00182121450.012
positive regulation of apoptotic processGO:00430652170.012
negative regulation of lipid catabolic processGO:005099560.012
regulation of cell migrationGO:00303342190.012
regulation of neuron projection developmentGO:00109751690.012
placenta developmentGO:00018901400.012
regulation of response to woundingGO:19030341890.012
b cell activationGO:00421131610.012
calcium ion homeostasisGO:00550741270.012
peptide secretionGO:00027901140.012
interleukin 8 productionGO:003263740.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
wnt signaling pathwayGO:00160551880.012
negative regulation of phosphate metabolic processGO:00459361840.012
cellular response to abiotic stimulusGO:0071214560.012
nucleoside metabolic processGO:00091162460.012
myeloid leukocyte differentiationGO:00025731190.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
small gtpase mediated signal transductionGO:0007264970.011
carbohydrate homeostasisGO:00335001280.011
negative regulation of cellular amino acid metabolic processGO:004576300.011
ear morphogenesisGO:00424711180.011
cell adhesionGO:00071553290.011
defense response to other organismGO:00985421970.011
nucleoside triphosphate catabolic processGO:00091432050.011
coenzyme a biosynthetic processGO:001593750.011
nuclear transportGO:00511691390.011
regulation of cytoplasmic transportGO:19036491120.011
Human
male sex differentiationGO:00466611090.011
skin developmentGO:00435882200.011
cellular response to gamma radiationGO:007148040.011
positive regulation of cytokine productionGO:00018191740.011
positive regulation of secretion by cellGO:19035321140.011
regulation of vesicle mediated transportGO:00606271390.011
Human
protein localization to organelleGO:00333651850.011
triglyceride biosynthetic processGO:0019432170.011
muscle contractionGO:00069361010.011
response to oxygen levelsGO:0070482620.011
nucleoside catabolic processGO:00091642060.011
rna interferenceGO:001624620.011
glycerolipid biosynthetic processGO:0045017500.011
methylationGO:00322591340.011
protein oligomerizationGO:0051259670.011
meiosis iGO:0007127600.011
sphingolipid metabolic processGO:0006665450.011
purine nucleotide biosynthetic processGO:0006164650.011
lateral inhibitionGO:004633110.011
aspartate family amino acid metabolic processGO:0009066100.011
oocyte constructionGO:000730820.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
negative regulation of proteolysisGO:0045861740.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
cellular response to insulin stimulusGO:0032869780.011
hematopoietic progenitor cell differentiationGO:00022441430.011
cellular response to peptideGO:1901653920.011
reactive nitrogen species metabolic processGO:200105700.011
defense response to bacteriumGO:00427421190.011
immune response regulating signaling pathwayGO:00027641250.011
positive regulation of cell activationGO:00508671580.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
asymmetric stem cell divisionGO:009872230.011
glucose metabolic processGO:0006006920.011
embryonic epithelial tube formationGO:00018381300.011
sequestering of metal ionGO:0051238190.011
tissue homeostasisGO:00018941150.011
fatty acid elongationGO:003049730.011
positive regulation of mapk cascadeGO:00434101700.010
urogenital system developmentGO:00016552610.010
cellular protein catabolic processGO:00442571550.010
alpha amino acid biosynthetic processGO:1901607150.010
response to starvationGO:0042594650.010
regulation of synaptic growth at neuromuscular junctionGO:000858240.010
regulation of cellular catabolic processGO:00313292420.010
positive regulation of t cell activationGO:00508701010.010
negative regulation of neuron apoptotic processGO:0043524920.010
cellularizationGO:000734910.010
regulation of endopeptidase activityGO:0052548890.010
rhodopsin mediated signaling pathwayGO:001605640.010
negative regulation of peptidase activityGO:0010466460.010
negative regulation of endopeptidase activityGO:0010951440.010
cognitionGO:00508901490.010
regulation of peptide transportGO:0090087910.010
cellular response to nutrient levelsGO:0031669640.010
regulation of protein processingGO:0070613960.010
triglyceride metabolic processGO:0006641510.010
cellular response to lipopolysaccharideGO:0071222770.010
developmental maturationGO:00217001930.010
positive regulation of lymphocyte activationGO:00512511400.010
heart processGO:0003015940.010
fertilizationGO:00095661270.010
renal system developmentGO:00720012250.010
detection of external stimulusGO:0009581610.010
regulation of protein kinase activityGO:00458592320.010
nucleoside triphosphate metabolic processGO:00091412300.010
histone modificationGO:00165701590.010
angiogenesisGO:00015252010.010
negative regulation of protein maturationGO:1903318790.010

Insig1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.046
inherited metabolic disorderDOID:65500.036
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.017
disease of cellular proliferationDOID:1456600.015
connective tissue diseaseDOID:6500.014
musculoskeletal system diseaseDOID:1700.014
cancerDOID:16200.012
immune system diseaseDOID:291400.011
cardiovascular system diseaseDOID:128700.011
bone diseaseDOID:008000100.010