Mus musculus

0 known processes

Slfn8

schlafen 8

(Aliases: MGC30719)

Slfn8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense response to other organismGO:00985421970.373
Human
defense response to virusGO:0051607680.364
Human
immune effector processGO:00022523210.352
Human
activation of innate immune responseGO:0002218560.349
regulation of innate immune responseGO:0045088910.252
regulation of defense responseGO:00313472330.180
cellular response to interferon betaGO:0035458210.144
interspecies interaction between organismsGO:0044419830.138
negative regulation of multi organism processGO:0043901680.134
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.130
negative regulation of immune system processGO:00026832090.128
symbiosis encompassing mutualism through parasitismGO:0044403830.122
viral processGO:0016032410.122
cytokine productionGO:00018163190.111
cellular response to interferon alphaGO:003545740.098
cellular nitrogen compound catabolic processGO:00442702800.092
cellular amino acid metabolic processGO:00065201030.090
positive regulation of innate immune responseGO:0045089800.089
innate immune responseGO:00450871570.087
defense response to bacteriumGO:00427421190.083
regulation of multi organism processGO:00439001110.082
purine containing compound metabolic processGO:00725213110.081
positive regulation of defense responseGO:00313491240.076
regulation of cellular ketone metabolic processGO:0010565660.076
regulation of defense response to virusGO:0050688180.075
positive regulation of cytokine productionGO:00018191740.074
rho protein signal transductionGO:0007266320.073
regulation of response to biotic stimulusGO:0002831380.068
aromatic compound catabolic processGO:00194392860.067
cellular amine metabolic processGO:0044106440.067
negative regulation of viral genome replicationGO:0045071100.064
protein ubiquitinationGO:00165671710.064
regulation of hydrolase activityGO:00513362460.063
response to interferon betaGO:0035456220.062
cellular response to cytokine stimulusGO:00713451890.061
regulation of cytokine productionGO:00018172660.061
nucleobase containing small molecule metabolic processGO:00550863520.061
regulation of nlrp3 inflammasome complex assemblyGO:190022540.061
positive regulation of viral genome replicationGO:004507020.060
organic cyclic compound catabolic processGO:19013612950.059
entry into cell of other organism involved in symbiotic interactionGO:0051806150.057
nucleoside phosphate metabolic processGO:00067533380.056
negative regulation of molecular functionGO:00440922580.052
mapk cascadeGO:00001652810.052
positive regulation of secretion by cellGO:19035321140.050
negative regulation of protein metabolic processGO:00512482820.048
heterocycle catabolic processGO:00467002800.046
cellular response to biotic stimulusGO:0071216920.045
negative regulation of hydrolase activityGO:0051346710.044
negative regulation of viral processGO:0048525230.044
amine metabolic processGO:0009308450.043
cellular ketone metabolic processGO:0042180840.043
cellular response to lipopolysaccharideGO:0071222770.042
nucleotide metabolic processGO:00091173320.042
carbohydrate derivative catabolic processGO:19011362310.041
regulation of cellular amino acid metabolic processGO:000652150.041
negative regulation of defense responseGO:0031348770.041
regulation of interferon beta productionGO:0032648130.040
negative regulation of nlrp3 inflammasome complex assemblyGO:190022620.039
regulation of cellular component biogenesisGO:00440871810.039
t cell activationGO:00421102890.038
purine nucleotide metabolic processGO:00061633020.038
protein modification by small protein conjugationGO:00324461870.038
ribonucleoside catabolic processGO:00424542060.038
ossificationGO:00015032160.037
organonitrogen compound catabolic processGO:19015652640.037
macromolecule catabolic processGO:00090572810.036
organophosphate catabolic processGO:00464342320.036
regulation of secretionGO:00510462740.035
positive regulation of cellular amine metabolic processGO:003324050.035
positive regulation of protein phosphorylationGO:00019342420.034
negative regulation of protein processingGO:0010955790.034
regulation of protein localizationGO:00328802310.034
protein processingGO:00164851630.034
protein modification by small protein conjugation or removalGO:00706472070.034
negative regulation of proteolysisGO:0045861740.034
negative regulation of cellular protein metabolic processGO:00322692470.033
viral transcriptionGO:001908330.033
regulation of cellular amine metabolic processGO:0033238200.033
purine ribonucleotide metabolic processGO:00091502900.032
glycosyl compound metabolic processGO:19016572460.032
ear developmentGO:00435832000.032
positive regulation of interferon alpha productionGO:003272740.032
nucleoside triphosphate metabolic processGO:00091412300.032
purine ribonucleoside triphosphate metabolic processGO:00092052200.032
carbohydrate metabolic processGO:00059752300.032
nucleoside phosphate catabolic processGO:19012922220.032
regulation of protein processingGO:0070613960.031
regulation of cytoskeleton organizationGO:00514931220.031
inflammatory responseGO:00069542440.030
myeloid cell differentiationGO:00300992330.030
regulation of establishment of protein localizationGO:00702011810.030
proteolysis involved in cellular protein catabolic processGO:00516031470.030
regulation of peptidase activityGO:0052547960.029
regulation of sequence specific dna binding transcription factor activityGO:00510901060.029
purine nucleoside metabolic processGO:00422782410.029
purine containing compound catabolic processGO:00725232130.029
ras protein signal transductionGO:0007265770.029
homeostasis of number of cellsGO:00488722100.029
positive regulation of secretionGO:00510471300.028
positive regulation of immune effector processGO:00026991070.028
positive regulation of cellular amino acid metabolic processGO:004576430.028
negative regulation of protein maturationGO:1903318790.027
positive regulation of cellular component biogenesisGO:0044089940.027
cellular response to lipidGO:00713961450.027
activation of immune responseGO:00022531380.027
muscle cell developmentGO:00550011330.027
viral life cycleGO:0019058360.027
negative regulation of endopeptidase activityGO:0010951440.027
purine ribonucleotide catabolic processGO:00091542080.027
regulation of organelle organizationGO:00330432890.026
purine ribonucleoside catabolic processGO:00461302050.026
guanosine containing compound metabolic processGO:19010681440.026
myeloid leukocyte differentiationGO:00025731190.026
regulation of cellular catabolic processGO:00313292420.026
regulation of protein maturationGO:1903317960.026
regulation of mapk cascadeGO:00434082480.026
small gtpase mediated signal transductionGO:0007264970.026
viral gene expressionGO:001908030.026
response to lipopolysaccharideGO:00324961280.025
guanosine containing compound catabolic processGO:19010691440.025
purine nucleoside triphosphate metabolic processGO:00091442260.025
negative regulation of cellular amine metabolic processGO:003323910.025
regulation of cysteine type endopeptidase activityGO:2000116650.024
nucleocytoplasmic transportGO:00069131390.024
cellular chemical homeostasisGO:00550822150.024
purine nucleotide catabolic processGO:00061952110.024
immune response regulating signaling pathwayGO:00027641250.024
muscle tissue developmentGO:00605373080.024
regulation of protein transportGO:00512231630.024
positive regulation of ossificationGO:0045778470.024
positive regulation of osteoblast differentiationGO:0045669340.024
regulation of ossificationGO:00302781120.024
cytoplasmic transportGO:00164822340.023
response to organic cyclic compoundGO:00140701980.023
response to molecule of bacterial originGO:00022371430.023
modification dependent protein catabolic processGO:00199411330.022
cellular macromolecule catabolic processGO:00442652060.022
negative regulation of viral transcriptionGO:003289730.022
modification dependent macromolecule catabolic processGO:00436321330.022
toll like receptor 7 signaling pathwayGO:003415440.022
purine nucleoside catabolic processGO:00061522050.022
skeletal muscle organ developmentGO:00605381630.022
ubiquitin dependent protein catabolic processGO:00065111290.022
nucleotide catabolic processGO:00091662170.022
glycosyl compound catabolic processGO:19016582060.022
purine ribonucleoside triphosphate catabolic processGO:00092071990.022
regulation of secretion by cellGO:19035302490.021
positive regulation of cytosolic calcium ion concentrationGO:0007204650.021
negative regulation of cytokine productionGO:0001818840.021
peptidyl amino acid modificationGO:00181933360.021
positive regulation of cell deathGO:00109422240.021
regulation of cytoplasmic transportGO:19036491120.021
regulation of osteoblast differentiationGO:0045667670.021
dna metabolic processGO:00062593030.021
reactive oxygen species metabolic processGO:0072593840.021
protein maturationGO:00516041760.020
viral genome replicationGO:0019079170.020
muscle cell differentiationGO:00426922610.020
ribose phosphate metabolic processGO:00196932910.020
regulation of actin cytoskeleton organizationGO:0032956840.020
purine ribonucleoside metabolic processGO:00461282410.019
regulation of cell cycleGO:00517262810.019
Human
negative regulation of cellular component organizationGO:00511291940.019
glycoprotein metabolic processGO:00091001160.019
organonitrogen compound biosynthetic processGO:19015661920.019
negative regulation of phosphorus metabolic processGO:00105631840.019
striated muscle tissue developmentGO:00147062930.019
regulation of protein secretionGO:0050708820.019
myotube differentiationGO:00149021050.019
sequestering of metal ionGO:0051238190.019
production of molecular mediator of immune responseGO:00024401030.019
nucleoside triphosphate catabolic processGO:00091432050.019
regulation of viral transcriptionGO:004678230.019
sequestering of calcium ionGO:0051208180.019
cellular response to hormone stimulusGO:00328701500.019
regulation of ras protein signal transductionGO:00465781140.019
regulation of purine nucleotide catabolic processGO:00331211220.019
nucleotide biosynthetic processGO:0009165780.019
cell type specific apoptotic processGO:00972852680.018
nucleoside metabolic processGO:00091162460.018
regulation of defense response to fungusGO:190015010.018
cellular homeostasisGO:00197252400.018
regulation of leukocyte mediated immunityGO:00027031040.018
i kappab kinase nf kappab signalingGO:0007249850.018
mitotic cytokinesisGO:000028140.018
actin polymerization or depolymerizationGO:0008154540.018
mitotic cell cycle processGO:19030471590.018
Human
macromolecule glycosylationGO:0043413550.018
organelle assemblyGO:00709251770.018
protein catabolic processGO:00301632210.018
ribonucleoside triphosphate catabolic processGO:00092031990.018
negative regulation of peptidase activityGO:0010466460.018
negative regulation of cellular amino acid metabolic processGO:004576300.017
chemokine productionGO:0032602340.017
regulation of proteolysisGO:00301621640.017
cation transportGO:00068123990.017
regulation of protein complex assemblyGO:0043254830.017
lymphocyte mediated immunityGO:00024491390.017
regulation of purine nucleotide metabolic processGO:19005421690.017
regulation of intracellular protein transportGO:0033157820.017
antimicrobial peptide productionGO:000277520.017
glycosylationGO:0070085620.017
proteasomal protein catabolic processGO:0010498980.017
protein secretionGO:00093061110.017
negative regulation of cell proliferationGO:00082852960.016
regulation of actin filament based processGO:0032970990.016
regulation of endopeptidase activityGO:0052548890.016
positive regulation of protein transportGO:0051222930.016
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.016
ribonucleoside metabolic processGO:00091192450.016
regulation of antimicrobial peptide biosynthetic processGO:000280510.016
response to growth factorGO:00708481980.016
purine nucleoside triphosphate catabolic processGO:00091462030.016
tumor necrosis factor superfamily cytokine productionGO:0071706510.016
spermatogenesisGO:00072832840.016
ribonucleotide metabolic processGO:00092592910.016
ribonucleotide catabolic processGO:00092612080.016
anatomical structure homeostasisGO:00602491450.016
negative regulation of cysteine type endopeptidase activityGO:2000117220.016
cellular response to molecule of bacterial originGO:0071219830.016
negative regulation of phosphorylationGO:00423261660.016
gtp catabolic processGO:00061841430.016
regulation of intracellular transportGO:00323861590.016
epithelial tube morphogenesisGO:00605623030.016
innate immune response activating signal transductionGO:0002758500.015
regulation of defense response to bacteriumGO:190042430.015
positive regulation of protein secretionGO:0050714520.015
regulation of type i interferon productionGO:0032479220.015
regulation of cell motilityGO:20001452360.015
regulation of protein catabolic processGO:00421761080.015
positive regulation of programmed cell deathGO:00430682180.015
positive regulation of actin nucleationGO:005112730.015
cellular component assembly involved in morphogenesisGO:00109271390.015
rna catabolic processGO:0006401290.015
leukocyte proliferationGO:00706611720.015
cellular protein complex assemblyGO:00436231160.015
ribonucleoside triphosphate metabolic processGO:00091992200.015
regulation of anatomical structure sizeGO:00900661780.015
microtubule based processGO:00070172360.015
metal ion homeostasisGO:00550651890.015
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.015
immune response activating signal transductionGO:00027571160.015
regulation of cell activationGO:00508652890.015
striated muscle cell developmentGO:00550021250.014
gtp metabolic processGO:00460391440.014
angiogenesisGO:00015252010.014
positive regulation of apoptotic processGO:00430652170.014
interferon beta productionGO:0032608160.014
positive regulation of mapk cascadeGO:00434101700.014
regulation of lymphocyte activationGO:00512492400.014
posttranscriptional regulation of gene expressionGO:00106081550.014
glycoprotein biosynthetic processGO:0009101890.014
organophosphate biosynthetic processGO:00904071220.014
regulation of cell migrationGO:00303342190.014
regulation of nucleotide metabolic processGO:00061401690.014
protein glycosylationGO:0006486550.014
positive regulation of viral entry into host cellGO:004659830.014
glucose homeostasisGO:00425931280.014
purine nucleotide biosynthetic processGO:0006164650.014
telencephalon developmentGO:00215371860.014
response to organonitrogen compoundGO:00102432460.014
nucleoside catabolic processGO:00091642060.014
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.013
negative regulation of cell developmentGO:00107211690.013
mitotic cell cycleGO:00002781950.013
Human
cellular ion homeostasisGO:00068731650.013
negative regulation of phosphate metabolic processGO:00459361840.013
regulation of antimicrobial humoral responseGO:000275930.013
sensory perceptionGO:00076002450.013
nucleoside phosphate biosynthetic processGO:1901293790.013
response to radiationGO:00093141650.013
regulation of homeostatic processGO:00328441820.013
b cell activationGO:00421131610.013
regulation of system processGO:00440572000.013
regulation of nucleoside metabolic processGO:00091181300.013
lymphocyte proliferationGO:00466511640.013
calcium ion homeostasisGO:00550741270.013
intracellular protein transportGO:00068862040.013
actin cytoskeleton organizationGO:00300362200.013
positive regulation of interleukin 18 productionGO:003274120.013
protein localization to nucleusGO:00345041210.013
regulation of bindingGO:00510981110.013
toll like receptor signaling pathwayGO:0002224380.013
positive regulation of hydrolase activityGO:00513451480.013
methylationGO:00322591340.013
maintenance of locationGO:0051235890.013
reactive oxygen species biosynthetic processGO:190340980.013
regulation of inflammatory responseGO:00507271470.013
antimicrobial peptide biosynthetic processGO:000277720.013
calcium ion transportGO:00068161590.013
stem cell developmentGO:00488642190.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.012
hematopoietic progenitor cell differentiationGO:00022441430.012
interleukin 8 productionGO:003263740.012
cellular lipid metabolic processGO:00442553230.012
forebrain developmentGO:00309003020.012
rna interferenceGO:001624620.012
cytokine secretionGO:0050663720.012
regulation of renin secretion into blood streamGO:190013340.012
carbohydrate derivative biosynthetic processGO:19011371830.012
regulation of antimicrobial peptide productionGO:000278410.012
regulation of viral genome replicationGO:0045069130.012
movement in environment of other organism involved in symbiotic interactionGO:0052192150.012
cation transmembrane transportGO:00986552660.012
cellular protein catabolic processGO:00442571550.012
negative regulation of viral entry into host cellGO:0046597100.012
myoblast differentiation involved in skeletal muscle regenerationGO:001483530.012
negative regulation of nervous system developmentGO:00519611560.012
limb morphogenesisGO:00351081490.012
intestinal epithelial structure maintenanceGO:006072940.012
regulation of leukocyte proliferationGO:00706631210.012
positive regulation of nucleotide catabolic processGO:0030813880.011
chromatin organizationGO:00063252060.011
cell adhesionGO:00071553290.011
regulation of kinase activityGO:00435492490.011
developmental maturationGO:00217001930.011
regulation of membrane potentialGO:00423911920.011
response to type i interferonGO:0034340120.011
response to interferon gammaGO:0034341340.011
dna modificationGO:0006304500.011
leukocyte differentiationGO:00025213420.011
regulation of striated muscle cell differentiationGO:0051153810.011
response to acid chemicalGO:00011011110.011
purine containing compound biosynthetic processGO:0072522700.011
circulatory system processGO:00030131970.011
regulation of hormone levelsGO:00108172110.011
t cell proliferationGO:00420981200.011
positive regulation of cell motilityGO:20001471160.011
regulation of neuron differentiationGO:00456642810.011
negative regulation of intracellular signal transductionGO:19025321670.011
transmembrane transportGO:00550854120.011
regulation of b cell activationGO:0050864810.011
negative regulation of interleukin 6 productionGO:0032715170.011
stem cell differentiationGO:00488632680.011
carbohydrate homeostasisGO:00335001280.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
cellular metal ion homeostasisGO:00068751510.011
multicellular organismal signalingGO:0035637910.011
leukocyte mediated immunityGO:00024431740.011
positive regulation of multi organism processGO:0043902260.011
erythrocyte differentiationGO:0030218880.011
morphogenesis of a branching structureGO:00017632030.011
regulation of chemokine productionGO:0032642300.010
nuclear transportGO:00511691390.010
positive regulation of response to biotic stimulusGO:0002833150.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
skin developmentGO:00435882200.010
positive regulation of purine nucleotide catabolic processGO:0033123880.010
interferon beta biosynthetic processGO:004535040.010
rig i signaling pathwayGO:003952940.010
positive regulation of purine nucleotide metabolic processGO:19005441140.010
chromatin modificationGO:00165681870.010
regulation of cell adhesionGO:00301551540.010
action potentialGO:0001508780.010
regulation of mitotic cell cycle phase transitionGO:1901990730.010
Human
transmission of nerve impulseGO:0019226760.010
adaptive immune responseGO:00022501550.010
defense response to gram negative bacteriumGO:0050829280.010
myeloid cell homeostasisGO:00022621140.010
compound eye developmentGO:004874910.010
extracellular structure organizationGO:00430621480.010
regulation of leukocyte differentiationGO:19021051590.010

Slfn8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.016
musculoskeletal system diseaseDOID:1700.011
disease of anatomical entityDOID:700.011