Mus musculus

119 known processes

Phactr4

phosphatase and actin regulator 4

(Aliases: N28169,KIAA4120,mKIAA4120,3110001B12Rik,AW495572,C330013F19Rik,AI527228,FLJ13171)

Phactr4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular ketone metabolic processGO:0042180840.082
protein modification by small protein conjugation or removalGO:00706472070.081
regulation of cellular amine metabolic processGO:0033238200.078
protein modification by small protein conjugationGO:00324461870.074
cellular amino acid metabolic processGO:00065201030.073
regulation of cellular amino acid metabolic processGO:000652150.071
cellular amine metabolic processGO:0044106440.060
positive regulation of cellular amino acid metabolic processGO:004576430.057
protein ubiquitinationGO:00165671710.056
regulation of organelle organizationGO:00330432890.055
positive regulation of cellular amine metabolic processGO:003324050.047
amine metabolic processGO:0009308450.046
cytokine productionGO:00018163190.046
regulation of cellular ketone metabolic processGO:0010565660.045
negative regulation of protein metabolic processGO:00512482820.045
negative regulation of cellular protein metabolic processGO:00322692470.044
macromolecule catabolic processGO:00090572810.044
cellular macromolecule catabolic processGO:00442652060.042
negative regulation of cellular amine metabolic processGO:003323910.041
peptidyl amino acid modificationGO:00181933360.038
nucleobase containing small molecule metabolic processGO:00550863520.037
leukocyte differentiationGO:00025213420.036
positive regulation of cell deathGO:00109422240.036
regulation of establishment of protein localizationGO:00702011810.035
nucleoside metabolic processGO:00091162460.034
protein catabolic processGO:00301632210.034
myeloid cell differentiationGO:00300992330.034
regulation of protein localizationGO:00328802310.033
regulation of cellular catabolic processGO:00313292420.032
regulation of cell cycleGO:00517262810.032
b cell activationGO:00421131610.032
heterocycle catabolic processGO:00467002800.032
regulation of membrane potentialGO:00423911920.032
negative regulation of protein modification processGO:00314001630.032
purine ribonucleotide metabolic processGO:00091502900.031
regulation of cytokine productionGO:00018172660.030
negative regulation of immune system processGO:00026832090.029
cellular response to dna damage stimulusGO:00069742070.029
cellular protein complex assemblyGO:00436231160.028
homeostasis of number of cellsGO:00488722100.028
striated muscle tissue developmentGO:00147062930.028
nucleotide metabolic processGO:00091173320.028
purine nucleotide metabolic processGO:00061633020.028
ribonucleotide metabolic processGO:00092592910.028
aromatic compound catabolic processGO:00194392860.028
positive regulation of apoptotic processGO:00430652170.028
nucleoside phosphate metabolic processGO:00067533380.027
axonogenesisGO:00074092740.027
ras protein signal transductionGO:0007265770.027
regulation of cell activationGO:00508652890.026
cellular chemical homeostasisGO:00550822150.026
regulation of lymphocyte activationGO:00512492400.026
organic cyclic compound catabolic processGO:19013612950.026
regulation of hydrolase activityGO:00513362460.025
organonitrogen compound biosynthetic processGO:19015661920.025
ribose phosphate metabolic processGO:00196932910.024
response to radiationGO:00093141650.024
actin cytoskeleton organizationGO:00300362200.024
cellular protein catabolic processGO:00442571550.024
negative regulation of cell proliferationGO:00082852960.024
carbohydrate derivative catabolic processGO:19011362310.024
modification dependent macromolecule catabolic processGO:00436321330.024
purine nucleoside metabolic processGO:00422782410.023
action potentialGO:0001508780.023
positive regulation of programmed cell deathGO:00430682180.023
transmembrane transportGO:00550854120.023
regulation of leukocyte differentiationGO:19021051590.023
ribonucleoside triphosphate metabolic processGO:00091992200.022
regulation of protein transportGO:00512231630.022
negative regulation of phosphate metabolic processGO:00459361840.022
epithelial cell proliferationGO:00506731740.022
compound eye developmentGO:004874910.022
rho protein signal transductionGO:0007266320.022
proteolysis involved in cellular protein catabolic processGO:00516031470.022
glycosyl compound metabolic processGO:19016572460.022
cell adhesionGO:00071553290.022
mapk cascadeGO:00001652810.022
organophosphate catabolic processGO:00464342320.022
nuclear divisionGO:00002801580.022
response to growth factorGO:00708481980.022
regulation of secretionGO:00510462740.022
regulation of neuron apoptotic processGO:00435231220.022
cellular nitrogen compound catabolic processGO:00442702800.022
actin filament polymerizationGO:0030041440.021
cation transmembrane transportGO:00986552660.021
cation transportGO:00068123990.021
nucleoside triphosphate metabolic processGO:00091412300.021
nucleoside phosphate catabolic processGO:19012922220.021
oxidation reduction processGO:00551143420.021
modification dependent protein catabolic processGO:00199411330.021
regulation of t cell activationGO:00508631700.021
regulation of neuron differentiationGO:00456642810.021
extracellular structure organizationGO:00430621480.021
regulation of anatomical structure sizeGO:00900661780.021
organonitrogen compound catabolic processGO:19015652640.020
cell type specific apoptotic processGO:00972852680.020
forebrain developmentGO:00309003020.020
small gtpase mediated signal transductionGO:0007264970.020
ribonucleoside triphosphate catabolic processGO:00092031990.020
organelle fissionGO:00482851700.020
muscle tissue developmentGO:00605373080.020
male gamete generationGO:00482322850.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.020
activation of immune responseGO:00022531380.020
regulation of cytoskeleton organizationGO:00514931220.020
purine ribonucleoside metabolic processGO:00461282410.020
purine containing compound catabolic processGO:00725232130.020
actin filament organizationGO:00070151130.020
purine ribonucleotide catabolic processGO:00091542080.020
regionalizationGO:00030023370.020
posttranscriptional regulation of gene expressionGO:00106081550.020
neuronal action potentialGO:0019228540.020
purine containing compound metabolic processGO:00725213110.020
skeletal system developmentGO:00015013560.020
t cell differentiationGO:00302171740.019
multicellular organismal signalingGO:0035637910.019
t cell activationGO:00421102890.019
cellular lipid metabolic processGO:00442553230.019
positive regulation of protein modification processGO:00314012990.019
regulation of transferase activityGO:00513382630.019
purine ribonucleoside catabolic processGO:00461302050.019
hematopoietic progenitor cell differentiationGO:00022441430.019
purine ribonucleoside triphosphate metabolic processGO:00092052200.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.019
organelle assemblyGO:00709251770.019
epithelial tube formationGO:00721751300.019
negative regulation of intracellular signal transductionGO:19025321670.019
negative regulation of cellular amino acid metabolic processGO:004576300.019
neuron deathGO:00709971540.019
purine nucleoside triphosphate catabolic processGO:00091462030.019
negative regulation of phosphorus metabolic processGO:00105631840.019
positive regulation of organelle organizationGO:00106381280.019
intracellular distribution of mitochondriaGO:004831210.019
regulation of secretion by cellGO:19035302490.018
ubiquitin dependent protein catabolic processGO:00065111290.018
membrane organizationGO:00610242450.018
covalent chromatin modificationGO:00165691630.018
camera type eye developmentGO:00430102660.018
regulation of apoptotic signaling pathwayGO:20012331970.018
regulation of cellular response to growth factor stimulusGO:0090287820.018
regulation of cell morphogenesis involved in differentiationGO:00107691510.018
cellular homeostasisGO:00197252400.018
carbohydrate derivative biosynthetic processGO:19011371830.018
lymphocyte differentiationGO:00300982420.018
reactive oxygen species metabolic processGO:0072593840.018
single organism cell adhesionGO:00986021560.018
purine nucleoside triphosphate metabolic processGO:00091442260.018
positive regulation of cellular catabolic processGO:00313311480.018
actin polymerization or depolymerizationGO:0008154540.018
mitochondrion distributionGO:004831140.018
apoptotic signaling pathwayGO:00971903060.018
nucleotide catabolic processGO:00091662170.018
stem cell developmentGO:00488642190.018
regulation of mitotic cell cycleGO:00073461260.018
cellular response to growth factor stimulusGO:00713631970.018
urogenital system developmentGO:00016552610.018
response to light stimulusGO:00094161350.017
glycosyl compound catabolic processGO:19016582060.017
renal system developmentGO:00720012250.017
negative regulation of molecular functionGO:00440922580.017
negative regulation of cellular component organizationGO:00511291940.017
immune response regulating signaling pathwayGO:00027641250.017
positive regulation of cytokine productionGO:00018191740.017
purine nucleoside catabolic processGO:00061522050.017
blood vessel morphogenesisGO:00485142850.017
regulation of cellular component sizeGO:00325351210.017
nucleoside catabolic processGO:00091642060.017
purine nucleotide catabolic processGO:00061952110.017
ion transmembrane transportGO:00342203610.017
connective tissue developmentGO:00614481790.017
protein localization to organelleGO:00333651850.017
cytoplasmic transportGO:00164822340.017
innate immune responseGO:00450871570.017
cell divisionGO:00513011200.017
chemotaxisGO:00069352470.017
cell growthGO:00160491300.017
lipid biosynthetic processGO:00086101790.017
epithelial cell developmentGO:00020641590.017
dna metabolic processGO:00062593030.017
stem cell maintenanceGO:00198271300.017
muscle cell differentiationGO:00426922610.016
multicellular organism growthGO:00352641610.016
regulation of feeding behaviorGO:006025930.016
cellular response to cytokine stimulusGO:00713451890.016
regulation of cell cycle processGO:00105641600.016
ribonucleotide catabolic processGO:00092612080.016
cellular response to organonitrogen compoundGO:00714171450.016
mitotic cell cycle processGO:19030471590.016
regulation of actin filament based processGO:0032970990.016
organelle localizationGO:00516401790.016
neuron apoptotic processGO:00514021420.016
embryonic epithelial tube formationGO:00018381300.016
regulation of hormone levelsGO:00108172110.016
multicellular organismal homeostasisGO:00488711640.016
mitotic cell cycleGO:00002781950.016
response to transforming growth factor betaGO:0071559880.016
synaptic transmissionGO:00072683290.016
regulation of cell projection organizationGO:00313442060.016
intracellular protein transportGO:00068862040.016
ear developmentGO:00435832000.016
organic hydroxy compound metabolic processGO:19016152030.016
respiratory system developmentGO:00605411900.016
protein polymerizationGO:0051258570.016
regulation of organ morphogenesisGO:20000271440.016
cellular response to transforming growth factor beta stimulusGO:0071560880.016
regulation of sequence specific dna binding transcription factor activityGO:00510901060.016
regulation of defense responseGO:00313472330.016
positive regulation of hydrolase activityGO:00513451480.016
nitrogen compound transportGO:00717052710.015
protein localization to nucleusGO:00345041210.015
ribonucleoside metabolic processGO:00091192450.015
regulation of proteolysisGO:00301621640.015
regulation of protein kinase activityGO:00458592320.015
inorganic cation transmembrane transportGO:00986622070.015
epithelial tube morphogenesisGO:00605623030.015
myeloid cell homeostasisGO:00022621140.015
developmental maturationGO:00217001930.015
regulation of b cell activationGO:0050864810.015
microtubule based processGO:00070172360.015
nucleoside triphosphate catabolic processGO:00091432050.015
immune effector processGO:00022523210.015
chromatin organizationGO:00063252060.015
regulation of nucleotide metabolic processGO:00061401690.015
regulation of purine nucleotide metabolic processGO:19005421690.015
lung developmentGO:00303241640.015
cell maturationGO:00484691270.015
response to organonitrogen compoundGO:00102432460.015
extracellular matrix organizationGO:00301981470.015
regulation of actin nucleationGO:005112540.015
dna repairGO:00062811070.014
regulation of cellular component biogenesisGO:00440871810.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.014
regulation of neuron deathGO:19012141340.014
respiratory tube developmentGO:00303231670.014
central nervous system neuron differentiationGO:00219531620.014
proteasomal protein catabolic processGO:0010498980.014
spermatogenesisGO:00072832840.014
myeloid leukocyte differentiationGO:00025731190.014
skin developmentGO:00435882200.014
microtubule cytoskeleton organizationGO:00002261570.014
ossificationGO:00015032160.014
glial cell apoptotic processGO:003434930.014
anatomical structure homeostasisGO:00602491450.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.014
response to organic cyclic compoundGO:00140701980.014
positive regulation of nucleotide metabolic processGO:00459811140.014
response to oxidative stressGO:00069791230.014
regulation of lymphocyte proliferationGO:00506701170.014
negative regulation of nik nf kappab signalingGO:190122320.014
organic anion transportGO:00157111370.014
regulation of synaptic growth at neuromuscular junctionGO:000858240.014
regulation of protein catabolic processGO:00421761080.014
positive regulation of purine nucleotide metabolic processGO:19005441140.014
glycoprotein metabolic processGO:00091001160.014
locomotory behaviorGO:00076261950.014
regulation of intracellular transportGO:00323861590.014
regulation of cellular response to stressGO:00801351590.014
ribonucleoside catabolic processGO:00424542060.014
methylationGO:00322591340.014
cellular response to hormone stimulusGO:00328701500.014
regulation of epithelial cell proliferationGO:00506781410.014
lateral inhibitionGO:004633110.014
maintenance of locationGO:0051235890.014
peptidyl tyrosine modificationGO:00182121450.014
mrna metabolic processGO:0016071840.014
gland developmentGO:00487323300.014
negative regulation of cytokine productionGO:0001818840.013
kidney developmentGO:00018222130.013
protein autophosphorylationGO:0046777610.013
nucleocytoplasmic transportGO:00069131390.013
positive regulation of proteolysisGO:0045862850.013
negative regulation of cell cycleGO:00457861230.013
protein import into nucleusGO:0006606950.013
lymphocyte proliferationGO:00466511640.013
production of molecular mediator of immune responseGO:00024401030.013
muscle system processGO:00030121410.013
medium chain fatty acid metabolic processGO:005179110.013
endocytosisGO:00068971680.013
myelinationGO:0042552740.013
peptidyl tyrosine phosphorylationGO:00181081430.013
heart morphogenesisGO:00030071780.013
leukocyte migrationGO:00509001240.013
regulation of neuron projection developmentGO:00109751690.013
protein maturationGO:00516041760.013
transmission of nerve impulseGO:0019226760.013
regulation of response to woundingGO:19030341890.013
wnt signaling pathwayGO:00160551880.013
protein targetingGO:00066051430.013
amide transportGO:00428861380.013
chromatin modificationGO:00165681870.013
nuclear transportGO:00511691390.013
histone modificationGO:00165701590.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
regulation of intracellular protein transportGO:0033157820.013
positive regulation of protein phosphorylationGO:00019342420.013
regulation of protein targetingGO:1903533610.013
cellular component assembly involved in morphogenesisGO:00109271390.013
activation of meiosis involved in egg activationGO:006046620.013
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.013
negative regulation of organelle organizationGO:0010639900.012
regulation of leukocyte proliferationGO:00706631210.012
endomembrane system organizationGO:00102561470.012
tissue homeostasisGO:00018941150.012
kidney epithelium developmentGO:00720731210.012
carbohydrate homeostasisGO:00335001280.012
branching morphogenesis of an epithelial tubeGO:00487541590.012
single organismal cell cell adhesionGO:00163371310.012
germ cell developmentGO:00072811850.012
positive regulation of gtp catabolic processGO:0033126850.012
regulation of kinase activityGO:00435492490.012
regulation of lipid metabolic processGO:00192161180.012
negative regulation of phosphorylationGO:00423261660.012
protein processingGO:00164851630.012
reactive nitrogen species metabolic processGO:200105700.012
regulation of vesicle mediated transportGO:00606271390.012
wound healingGO:00420601570.012
neural tube developmentGO:00219151600.012
guanosine containing compound catabolic processGO:19010691440.012
regulation of osteoblast differentiationGO:0045667670.012
development of primary sexual characteristicsGO:00451371430.012
organophosphate biosynthetic processGO:00904071220.012
negative regulation of protein phosphorylationGO:00019331260.012
response to oxygen levelsGO:0070482620.012
regulation of cell adhesionGO:00301551540.012
monocarboxylic acid metabolic processGO:00327871910.012
heparin biosynthetic processGO:003021020.012
anion transportGO:00068201770.012
b cell differentiationGO:0030183780.012
peptidyl serine phosphorylationGO:0018105740.012
activation of mapk activity involved in innate immune responseGO:003541920.012
g protein coupled receptor signaling pathwayGO:00071862430.012
embryonic organ morphogenesisGO:00485622760.012
axon ensheathmentGO:0008366760.012
ensheathment of neuronsGO:0007272760.012
positive regulation of nucleoside metabolic processGO:0045979910.012
regulation of protein complex assemblyGO:0043254830.012
rna processingGO:00063961050.012
mitochondrion organizationGO:00070051340.012
skeletal muscle organ developmentGO:00605381630.012
adaptive immune responseGO:00022501550.012
glucose homeostasisGO:00425931280.012
positive regulation of cell developmentGO:00107202370.012
gliogenesisGO:00420631410.012
regulation of myeloid leukocyte differentiationGO:0002761580.011
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.011
positive regulation of macroautophagyGO:001623930.011
positive regulation of interleukin 8 secretionGO:200048410.011
protein localization to membraneGO:00726571080.011
positive regulation of cellular component biogenesisGO:0044089940.011
morphogenesis of a branching structureGO:00017632030.011
protein localization to plasma membraneGO:0072659570.011
peptide transportGO:00158331330.011
circulatory system processGO:00030131970.011
regulation of actin polymerization or depolymerizationGO:0008064450.011
regulation of gtp catabolic processGO:00331241130.011
regulation of protein modification by small protein conjugation or removalGO:1903320570.011
negative regulation of lymphocyte activationGO:0051250910.011
retrograde transport endosome to golgiGO:004214720.011
regulation of actin cytoskeleton organizationGO:0032956840.011
sensory organ morphogenesisGO:00905962420.011
cognitionGO:00508901490.011
rhythmic processGO:00485111740.011
myosin filament assemblyGO:003103420.011
gtp metabolic processGO:00460391440.011
cartilage developmentGO:00512161400.011
intestinal epithelial structure maintenanceGO:006072940.011
organism emergence from protective structureGO:007168440.011
establishment of blood nerve barrierGO:000806530.011
regulation of multi organism processGO:00439001110.011
myosin filament organizationGO:003103330.011
regulation of cell motilityGO:20001452360.011
antimicrobial peptide biosynthetic processGO:000277720.011
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.011
modification by symbiont of host morphology or physiologyGO:004400340.011
meiotic nuclear divisionGO:00071261150.011
regulation of antimicrobial humoral responseGO:000275930.011
negative regulation of glial cell proliferationGO:006025340.011
striated muscle myosin thick filament assemblyGO:007168810.011
negative regulation of t cell activationGO:0050868650.011
mesenchymal cell differentiationGO:00487621070.011
leukocyte proliferationGO:00706611720.011
regulation of myeloid cell differentiationGO:0045637960.011
gtp catabolic processGO:00061841430.011
regulation of cell cell adhesion mediated by cadherinGO:200004720.011
regulation of protein serine threonine kinase activityGO:00719001570.010
regulation of t cell proliferationGO:0042129920.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
kidney rudiment formationGO:007200330.010
placenta developmentGO:00018901400.010
negative regulation of cell activationGO:00508661110.010
small molecule biosynthetic processGO:00442831320.010
antimicrobial peptide productionGO:000277520.010
nephron epithelium developmentGO:0072009920.010
negative regulation of growthGO:0045926990.010
regulation of mapk cascadeGO:00434082480.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.010
purine nucleoside monophosphate metabolic processGO:0009126810.010
drug catabolic processGO:004273720.010
regulation of cytoplasmic transportGO:19036491120.010
positive regulation of apoptotic signaling pathwayGO:2001235950.010
positive regulation of interleukin 8 productionGO:003275720.010
establishment or maintenance of cell polarityGO:0007163860.010
regulation of lymphocyte differentiationGO:00456191070.010
cation homeostasisGO:00550802120.010
b cell proliferationGO:0042100530.010
skeletal system morphogenesisGO:00487052030.010
regulation of nucleotide catabolic processGO:00308111220.010
transforming growth factor beta receptor signaling pathwayGO:0007179710.010
morphogenesis of embryonic epitheliumGO:00163311590.010
cell substrate adhesionGO:00315891300.010
regulation of protein processingGO:0070613960.010
myotube differentiation involved in skeletal muscle regenerationGO:001490820.010
regulation of cell growthGO:0001558910.010
positive regulation of secretionGO:00510471300.010
regulation of nucleoside metabolic processGO:00091181300.010
regulation of protein localization to nucleusGO:1900180600.010
response to extracellular stimulusGO:00099911270.010
regulation of cell divisionGO:0051302760.010
fatty acid metabolic processGO:00066311210.010

Phactr4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.027
organ system cancerDOID:005068600.027
disease of cellular proliferationDOID:1456600.027
disease of anatomical entityDOID:700.026
nervous system diseaseDOID:86300.026
disease of metabolismDOID:001466700.022
immune system diseaseDOID:291400.022
central nervous system diseaseDOID:33100.019
inherited metabolic disorderDOID:65500.017
sensory system diseaseDOID:005015500.015
eye and adnexa diseaseDOID:149200.015
eye diseaseDOID:561400.015
hematopoietic system diseaseDOID:7400.013
neurodegenerative diseaseDOID:128900.011
retinal diseaseDOID:567900.011
anemiaDOID:235500.011