Mus musculus

0 known processes

Usp53

ubiquitin specific peptidase 53

(Aliases: Phxr3,AA939927,mKIAA1350,Sp6)

Usp53 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation transportGO:00068123990.129
small gtpase mediated signal transductionGO:0007264970.115
protein modification by small protein conjugation or removalGO:00706472070.098
rho protein signal transductionGO:0007266320.095
modification dependent macromolecule catabolic processGO:00436321330.075
protein catabolic processGO:00301632210.067
protein modification by small protein conjugationGO:00324461870.065
cellular ketone metabolic processGO:0042180840.062
ribose phosphate metabolic processGO:00196932910.061
transmembrane transportGO:00550854120.060
nucleobase containing small molecule metabolic processGO:00550863520.059
regulation of nucleotide metabolic processGO:00061401690.059
regulation of cellular amino acid metabolic processGO:000652150.057
ras protein signal transductionGO:0007265770.055
macromolecule catabolic processGO:00090572810.054
cellular nitrogen compound catabolic processGO:00442702800.053
regulation of t cell activationGO:00508631700.052
cation transmembrane transportGO:00986552660.051
nucleoside phosphate metabolic processGO:00067533380.050
nucleoside catabolic processGO:00091642060.050
intracellular protein transportGO:00068862040.050
amine metabolic processGO:0009308450.049
regulation of cellular amine metabolic processGO:0033238200.048
cellular lipid metabolic processGO:00442553230.048
ubiquitin dependent protein catabolic processGO:00065111290.047
cytoplasmic transportGO:00164822340.045
regulation of cellular ketone metabolic processGO:0010565660.044
purine ribonucleotide metabolic processGO:00091502900.043
positive regulation of cellular catabolic processGO:00313311480.043
sodium ion transportGO:0006814730.043
heterocycle catabolic processGO:00467002800.043
actin cytoskeleton organizationGO:00300362200.042
purine nucleotide metabolic processGO:00061633020.042
cellular amine metabolic processGO:0044106440.042
regulation of protein localizationGO:00328802310.042
positive regulation of cell deathGO:00109422240.042
regulation of lymphocyte activationGO:00512492400.042
cellular macromolecule catabolic processGO:00442652060.042
leukocyte proliferationGO:00706611720.041
inorganic cation transmembrane transportGO:00986622070.040
ion transmembrane transportGO:00342203610.039
cytokine productionGO:00018163190.039
nucleotide catabolic processGO:00091662170.039
nucleotide metabolic processGO:00091173320.039
cell cell junction organizationGO:0045216720.038
organelle localizationGO:00516401790.038
regulation of cell activationGO:00508652890.038
nucleoside triphosphate metabolic processGO:00091412300.037
carbohydrate derivative catabolic processGO:19011362310.037
cellular amino acid metabolic processGO:00065201030.037
endocytosisGO:00068971680.036
organonitrogen compound catabolic processGO:19015652640.036
lymphocyte proliferationGO:00466511640.036
negative regulation of phosphorylationGO:00423261660.036
peptidyl amino acid modificationGO:00181933360.036
negative regulation of molecular functionGO:00440922580.035
proteolysis involved in cellular protein catabolic processGO:00516031470.035
purine nucleoside catabolic processGO:00061522050.035
purine containing compound metabolic processGO:00725213110.035
regulation of ion transportGO:00432692150.034
cell adhesionGO:00071553290.034
regulation of cellular component biogenesisGO:00440871810.034
protein ubiquitinationGO:00165671710.034
epithelial tube morphogenesisGO:00605623030.034
modification dependent protein catabolic processGO:00199411330.033
nucleoside triphosphate catabolic processGO:00091432050.033
purine ribonucleotide catabolic processGO:00091542080.033
synaptic transmissionGO:00072683290.032
regulation of cell migrationGO:00303342190.032
organophosphate catabolic processGO:00464342320.032
purine nucleotide catabolic processGO:00061952110.032
regulation of cytoskeleton organizationGO:00514931220.032
regulation of intracellular transportGO:00323861590.032
nucleoside metabolic processGO:00091162460.032
negative regulation of intracellular signal transductionGO:19025321670.032
negative regulation of cell activationGO:00508661110.032
regulation of leukocyte proliferationGO:00706631210.032
regulation of nucleoside metabolic processGO:00091181300.032
cellular response to dna damage stimulusGO:00069742070.031
regulation of metal ion transportGO:00109591060.031
microtubule cytoskeleton organizationGO:00002261570.031
regulation of neuron differentiationGO:00456642810.030
positive regulation of cellular amine metabolic processGO:003324050.030
tube formationGO:00351481400.030
blood circulationGO:00080151950.030
nucleoside phosphate catabolic processGO:19012922220.029
regulation of organelle organizationGO:00330432890.029
inorganic ion transmembrane transportGO:00986602340.029
purine ribonucleoside catabolic processGO:00461302050.029
ribonucleoside triphosphate catabolic processGO:00092031990.029
regulation of purine nucleotide catabolic processGO:00331211220.029
regulation of mapk cascadeGO:00434082480.029
ribonucleoside catabolic processGO:00424542060.028
regulation of cell motilityGO:20001452360.028
mapk cascadeGO:00001652810.028
oxidation reduction processGO:00551143420.028
cellular protein catabolic processGO:00442571550.028
ribonucleoside metabolic processGO:00091192450.028
t cell activationGO:00421102890.028
protein modification by small protein removalGO:0070646210.027
ribonucleotide metabolic processGO:00092592910.027
vesicle localizationGO:0051648860.027
negative regulation of phosphorus metabolic processGO:00105631840.027
aromatic compound catabolic processGO:00194392860.027
regulation of cellular component sizeGO:00325351210.027
protein targetingGO:00066051430.027
regulation of gtp catabolic processGO:00331241130.027
purine nucleoside triphosphate metabolic processGO:00091442260.027
guanosine containing compound metabolic processGO:19010681440.027
protein localization to organelleGO:00333651850.027
adaptive immune responseGO:00022501550.027
cellular homeostasisGO:00197252400.026
ribonucleoside triphosphate metabolic processGO:00091992200.026
apoptotic signaling pathwayGO:00971903060.026
microtubule based processGO:00070172360.026
glycosyl compound metabolic processGO:19016572460.026
cell type specific apoptotic processGO:00972852680.026
organic cyclic compound catabolic processGO:19013612950.026
actin filament organizationGO:00070151130.026
forebrain developmentGO:00309003020.026
respiratory system developmentGO:00605411900.026
regulation of cell projection organizationGO:00313442060.026
positive regulation of programmed cell deathGO:00430682180.025
regulation of purine nucleotide metabolic processGO:19005421690.025
regulation of ion transmembrane transportGO:00347651190.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
purine ribonucleoside triphosphate metabolic processGO:00092052200.024
purine nucleoside metabolic processGO:00422782410.024
purine containing compound catabolic processGO:00725232130.024
negative regulation of cellular amino acid metabolic processGO:004576300.024
regulation of lymphocyte proliferationGO:00506701170.024
nitrogen compound transportGO:00717052710.024
regulation of cytokine productionGO:00018172660.024
respiratory tube developmentGO:00303231670.024
nucleocytoplasmic transportGO:00069131390.024
negative regulation of immune system processGO:00026832090.024
regulation of apoptotic signaling pathwayGO:20012331970.024
regulation of t cell proliferationGO:0042129920.024
circulatory system processGO:00030131970.024
negative regulation of cell proliferationGO:00082852960.024
regulation of hydrolase activityGO:00513362460.023
camera type eye developmentGO:00430102660.023
cellular response to lipidGO:00713961450.023
epithelial cell developmentGO:00020641590.023
embryonic epithelial tube formationGO:00018381300.023
muscle system processGO:00030121410.023
positive regulation of protein modification processGO:00314012990.023
maintenance of locationGO:0051235890.023
guanosine containing compound catabolic processGO:19010691440.022
regulation of cell cycleGO:00517262810.022
muscle cell differentiationGO:00426922610.022
divalent inorganic cation transportGO:00725111780.022
purine nucleoside triphosphate catabolic processGO:00091462030.022
purine ribonucleoside triphosphate catabolic processGO:00092071990.022
peptidyl serine phosphorylationGO:0018105740.022
establishment of organelle localizationGO:00516561220.022
positive regulation of hydrolase activityGO:00513451480.022
regulation of transmembrane transportGO:00347621280.022
regulation of proteolysisGO:00301621640.022
protein localization to nucleusGO:00345041210.021
regulation of anatomical structure sizeGO:00900661780.021
epithelial tube formationGO:00721751300.021
heart morphogenesisGO:00030071780.021
stem cell proliferationGO:00720891170.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.021
neural tube formationGO:00018411080.021
ribonucleotide catabolic processGO:00092612080.021
negative regulation of t cell activationGO:0050868650.021
protein polymerizationGO:0051258570.021
sodium ion transmembrane transportGO:0035725490.021
axonogenesisGO:00074092740.021
blood vessel morphogenesisGO:00485142850.021
morphogenesis of embryonic epitheliumGO:00163311590.021
organic anion transportGO:00157111370.021
wnt signaling pathwayGO:00160551880.021
regulation of synaptic growth at neuromuscular junctionGO:000858240.020
divalent metal ion transportGO:00708381720.020
negative regulation of protein metabolic processGO:00512482820.020
purine ribonucleoside metabolic processGO:00461282410.020
histone modificationGO:00165701590.020
regulation of protein kinase activityGO:00458592320.020
regulation of cellular catabolic processGO:00313292420.020
skeletal system developmentGO:00015013560.020
lipid biosynthetic processGO:00086101790.020
regulation of lipid metabolic processGO:00192161180.020
gland developmentGO:00487323300.020
carbohydrate derivative biosynthetic processGO:19011371830.020
regulation of ras protein signal transductionGO:00465781140.020
cell divisionGO:00513011200.020
proteasomal protein catabolic processGO:0010498980.020
glycosyl compound catabolic processGO:19016582060.019
neural tube developmentGO:00219151600.019
negative regulation of lymphocyte activationGO:0051250910.019
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.019
cellular protein complex assemblyGO:00436231160.019
cellular alcohol biosynthetic processGO:004410830.019
negative regulation of cell sizeGO:004579230.019
cellular ion homeostasisGO:00068731650.019
cation homeostasisGO:00550802120.019
gtp catabolic processGO:00061841430.019
regulation of protein transportGO:00512231630.019
muscle tissue developmentGO:00605373080.019
organic hydroxy compound metabolic processGO:19016152030.019
regulation of hormone levelsGO:00108172110.019
neural tube closureGO:0001843900.019
leukocyte migrationGO:00509001240.018
positive regulation of apoptotic processGO:00430652170.018
cell junction organizationGO:0034330770.018
regulation of kinase activityGO:00435492490.018
regulation of transferase activityGO:00513382630.018
regulation of nucleotide catabolic processGO:00308111220.018
positive regulation of nervous system developmentGO:00519622210.018
positive regulation of protein kinase activityGO:00458601440.018
digestive tract developmentGO:00485651900.018
regulation of calcium ion transportGO:0051924690.018
mitotic cell cycleGO:00002781950.018
nuclear transportGO:00511691390.018
angiogenesisGO:00015252010.018
negative regulation of phosphate metabolic processGO:00459361840.018
organelle fissionGO:00482851700.017
sensory perceptionGO:00076002450.017
response to radiationGO:00093141650.017
immune effector processGO:00022523210.017
spermatogenesisGO:00072832840.017
canonical wnt signaling pathwayGO:00600701300.017
nuclear importGO:0051170950.017
regulation of sodium ion transportGO:0002028290.017
lung developmentGO:00303241640.017
negative regulation of lymphocyte proliferationGO:0050672450.017
establishment of vesicle localizationGO:0051650810.017
positive regulation of mapk cascadeGO:00434101700.017
embryonic organ morphogenesisGO:00485622760.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.017
anion transportGO:00068201770.017
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.017
regulation of actin filament based processGO:0032970990.016
response to organic cyclic compoundGO:00140701980.016
glycoprotein metabolic processGO:00091001160.016
protein importGO:00170381010.016
male courtship behaviorGO:000804920.016
regulation of cellular response to stressGO:00801351590.016
male gamete generationGO:00482322850.016
cellular response to organonitrogen compoundGO:00714171450.016
myotube differentiationGO:00149021050.016
ameboidal type cell migrationGO:00016671280.016
exocytosisGO:00068871210.016
regulation of protein catabolic processGO:00421761080.016
positive regulation of organelle organizationGO:00106381280.016
multicellular organism growthGO:00352641610.016
positive regulation of protein phosphorylationGO:00019342420.016
negative regulation of cellular amine metabolic processGO:003323910.016
peptidyl serine modificationGO:0018209830.016
posttranscriptional regulation of gene expressionGO:00106081550.015
digestive system developmentGO:00551232000.015
cellular chemical homeostasisGO:00550822150.015
neural precursor cell proliferationGO:00613511210.015
calcium ion homeostasisGO:00550741270.015
extrinsic apoptotic signaling pathwayGO:00971911260.015
negative regulation of ossificationGO:0030279490.015
regulation of cytoplasmic transportGO:19036491120.015
b cell activationGO:00421131610.015
positive regulation of ion transportGO:0043270650.015
sensory organ morphogenesisGO:00905962420.015
establishment of protein localization to organelleGO:00725941180.015
ossificationGO:00015032160.015
calcium ion transportGO:00068161590.015
t cell proliferationGO:00420981200.015
positive regulation of purine nucleotide metabolic processGO:19005441140.015
cell substrate adhesionGO:00315891300.015
synapse organizationGO:00508081250.015
positive regulation of ras gtpase activityGO:0032320650.015
regulation of neuron projection developmentGO:00109751690.015
cell junction assemblyGO:0034329520.015
response to molecule of bacterial originGO:00022371430.015
positive regulation of lymphocyte activationGO:00512511400.014
germ cell developmentGO:00072811850.014
regulation of secretionGO:00510462740.014
regulation of sequence specific dna binding transcription factor activityGO:00510901060.014
organic acid biosynthetic processGO:0016053860.014
positive regulation of gtpase activityGO:0043547850.014
pharynx developmentGO:006046510.014
negative regulation of cellular protein metabolic processGO:00322692470.014
compound eye developmentGO:004874910.014
regulation of vesicle mediated transportGO:00606271390.014
lipid localizationGO:00108761260.014
rna processingGO:00063961050.014
regulation of protein complex assemblyGO:0043254830.014
cell cell junction assemblyGO:0007043270.014
gtp metabolic processGO:00460391440.014
urogenital system developmentGO:00016552610.014
mitotic cell cycle processGO:19030471590.014
negative regulation of leukocyte proliferationGO:0070664460.014
regulation of secretion by cellGO:19035302490.014
negative regulation of protein phosphorylationGO:00019331260.014
divalent inorganic cation homeostasisGO:00725071380.014
regulation of ossificationGO:00302781120.014
extracellular structure organizationGO:00430621480.014
negative regulation of bmp signaling pathwayGO:0030514350.014
hindbrain developmentGO:00309021280.013
positive regulation of transferase activityGO:00513471670.013
striated muscle tissue developmentGO:00147062930.013
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.013
cellular metal ion homeostasisGO:00068751510.013
positive regulation of nucleotide metabolic processGO:00459811140.013
nuclear divisionGO:00002801580.013
lipid transportGO:0006869980.013
cellularizationGO:000734910.013
negative regulation of t cell proliferationGO:0042130380.013
kidney developmentGO:00018222130.013
regulation of rho gtpase activityGO:0032319580.013
regulation of actin cytoskeleton organizationGO:0032956840.013
response to organonitrogen compoundGO:00102432460.013
hematopoietic progenitor cell differentiationGO:00022441430.013
muscle cell developmentGO:00550011330.013
homeostasis of number of cellsGO:00488722100.013
defecationGO:003042110.013
cardiac muscle contractionGO:0060048320.013
neurotransmitter secretionGO:0007269620.013
positive regulation of cytokine productionGO:00018191740.013
maintenance of epithelial cell apical basal polarityGO:004519920.013
cofactor biosynthetic processGO:0051188410.013
actin filament bundle assemblyGO:0051017400.013
single organism cell adhesionGO:00986021560.013
alpha beta t cell activationGO:0046631910.013
myeloid cell differentiationGO:00300992330.013
phospholipid metabolic processGO:0006644870.013
reactive oxygen species metabolic processGO:0072593840.013
response to inorganic substanceGO:0010035960.013
female gamete generationGO:0007292740.013
endomembrane system organizationGO:00102561470.013
mesodermal cell migrationGO:000807840.013
organonitrogen compound biosynthetic processGO:19015661920.013
leukocyte activation involved in immune responseGO:00023661260.013
protein import into nucleusGO:0006606950.013
positive regulation of gtp catabolic processGO:0033126850.013
immune response regulating signaling pathwayGO:00027641250.013
neurotransmitter transportGO:0006836760.012
protein maturationGO:00516041760.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.012
coenzyme biosynthetic processGO:0009108230.012
regulation of ras gtpase activityGO:0032318880.012
organic hydroxy compound transportGO:0015850930.012
positive regulation of kinase activityGO:00336741550.012
response to lipopolysaccharideGO:00324961280.012
developmental maturationGO:00217001930.012
organic acid transportGO:00158491010.012
heart contractionGO:0060047930.012
positive regulation of tor signalingGO:003200830.012
negative regulation of cellular component organizationGO:00511291940.012
carbohydrate metabolic processGO:00059752300.012
cellular response to hormone stimulusGO:00328701500.012
oocyte axis specificationGO:000730920.012
small molecule biosynthetic processGO:00442831320.012
positive regulation of cell activationGO:00508671580.012
asymmetric stem cell divisionGO:009872230.012
regulation of cell adhesionGO:00301551540.012
leukocyte mediated immunityGO:00024431740.012
muscle contractionGO:00069361010.012
positive regulation of protein catabolic processGO:0045732600.012
neuronal action potentialGO:0019228540.012
g protein coupled receptor signaling pathwayGO:00071862430.012
cellular response to biotic stimulusGO:0071216920.012
cell maturationGO:00484691270.012
negative regulation of wnt signaling pathwayGO:0030178730.012
multicellular organismal signalingGO:0035637910.012
positive regulation of nucleoside metabolic processGO:0045979910.012
cell fate commitmentGO:00451652100.012
positive regulation of cell developmentGO:00107202370.012
glycerolipid metabolic processGO:00464861220.012
dna metabolic processGO:00062593030.012
regulation of b cell activationGO:0050864810.012
metal ion homeostasisGO:00550651890.012
fat cell differentiationGO:00454441600.012
positive regulation of cytoskeleton organizationGO:0051495490.011
cofactor metabolic processGO:0051186800.011
digestive tract morphogenesisGO:00485461470.011
central nervous system neuron differentiationGO:00219531620.011
renal system developmentGO:00720012250.011
positive regulation of cell motilityGO:20001471160.011
regulation of system processGO:00440572000.011
establishment of synaptic vesicle localizationGO:0097480570.011
cellular response to abiotic stimulusGO:0071214560.011
cell recognitionGO:0008037830.011
leukocyte differentiationGO:00025213420.011
cellular calcium ion homeostasisGO:00068741190.011
response to oxidative stressGO:00069791230.011
covalent chromatin modificationGO:00165691630.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
monocarboxylic acid metabolic processGO:00327871910.011
metencephalon developmentGO:0022037890.011
regulation of nucleocytoplasmic transportGO:0046822730.011
lymphocyte differentiationGO:00300982420.011
single organism nuclear importGO:1902593950.011
response to growth factorGO:00708481980.011
protein oligomerizationGO:0051259670.011
positive regulation of proteolysisGO:0045862850.011
action potentialGO:0001508780.011
positive regulation of cellular component biogenesisGO:0044089940.011
regulation of rho protein signal transductionGO:0035023710.011
regulation of endopeptidase activityGO:0052548890.011
single organismal cell cell adhesionGO:00163371310.011
organophosphate biosynthetic processGO:00904071220.011
peptide transportGO:00158331330.011
immune response regulating cell surface receptor signaling pathwayGO:0002768800.011
oocyte constructionGO:000730820.011
amide transportGO:00428861380.011
regulation of intracellular protein transportGO:0033157820.011
carbohydrate homeostasisGO:00335001280.011
cell activation involved in immune responseGO:00022631260.011
regulation of protein serine threonine kinase activityGO:00719001570.011
response to acid chemicalGO:00011011110.011
protein localization to cell junctionGO:190241430.011
carboxylic acid biosynthetic processGO:0046394860.011
lateral inhibitionGO:004633110.011
glycoprotein biosynthetic processGO:0009101890.011
female meiosis chromosome segregationGO:001632110.010
negative regulation of mapk cascadeGO:0043409650.010
positive regulation of t cell activationGO:00508701010.010
regulation of canonical wnt signaling pathwayGO:0060828820.010
negative regulation of synapse assemblyGO:005196430.010
p38mapk cascadeGO:003806640.010
regulation of myotube differentiationGO:0010830620.010
endodermal cell fate specificationGO:000171440.010
maintenance of apical basal cell polarityGO:003509030.010
t cell differentiationGO:00302171740.010
regulation of map kinase activityGO:00434051200.010
defense response to other organismGO:00985421970.010
regulation of mitotic cell cycleGO:00073461260.010
connective tissue developmentGO:00614481790.010
regulation of protein maturationGO:1903317960.010
glucose homeostasisGO:00425931280.010
bmp signaling pathwayGO:0030509930.010
negative regulation of transferase activityGO:0051348850.010
regulation of establishment of protein localizationGO:00702011810.010
epithelial cell proliferationGO:00506731740.010
regulation of protein kinase b signalingGO:0051896560.010
plasma membrane organizationGO:0007009900.010

Usp53 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.028
organ system cancerDOID:005068600.028
cancerDOID:16200.028
musculoskeletal system diseaseDOID:1700.015
disease of anatomical entityDOID:700.015
nervous system diseaseDOID:86300.013
connective tissue diseaseDOID:6500.012
bone diseaseDOID:008000100.012
immune system diseaseDOID:291400.011