IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Mpnd

MPN domain containing

(Aliases: E130307M08Rik)

Ensembl: ENSMUSG00000003199
Entrez: 68047
UniProtKB: Q3TV65

Process Predictions
Disease Predictions

Mpnd biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
monocarboxylic acid metabolic process	GO:0032787	191	0.111
nucleobase containing small molecule metabolic process	GO:0055086	352	0.080
regulation of cellular ketone metabolic process	GO:0010565	66	0.078
oxidation reduction process	GO:0055114	342	0.068
cellular ketone metabolic process	GO:0042180	84	0.068
cellular lipid metabolic process	GO:0044255	323	0.067
regulation of cellular amine metabolic process	GO:0033238	20	0.051
amine metabolic process	GO:0009308	45	0.051
cellular amino acid metabolic process	GO:0006520	103	0.049
organic cyclic compound catabolic process	GO:1901361	295	0.044
nucleotide metabolic process	GO:0009117	332	0.041
steroid metabolic process	GO:0008202	119	0.040
nucleoside phosphate metabolic process	GO:0006753	338	0.040
response to light stimulus	GO:0009416	135	0.038
fatty acid metabolic process	GO:0006631	121	0.037
ribose phosphate metabolic process	GO:0019693	291	0.037
nucleoside metabolic process	GO:0009116	246	0.036
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.035
camera type eye development	GO:0043010	266	0.034
cellular amine metabolic process	GO:0044106	44	0.034
translation	GO:0006412	93	0.031
muscle cell differentiation	GO:0042692	261	0.030
nucleoside phosphate catabolic process	GO:1901292	222	0.030
lipid biosynthetic process	GO:0008610	179	0.029
regulation of system process	GO:0044057	200	0.029
organonitrogen compound catabolic process	GO:1901565	264	0.029
glycosyl compound metabolic process	GO:1901657	246	0.028
regulation of peptide transport	GO:0090087	91	0.028
positive regulation of cellular amine metabolic process	GO:0033240	5	0.027
regulation of cellular amino acid metabolic process	GO:0006521	5	0.027
telencephalon development	GO:0021537	186	0.027
organic hydroxy compound metabolic process	GO:1901615	203	0.027
cellular nitrogen compound catabolic process	GO:0044270	280	0.026
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.026
urogenital system development	GO:0001655	261	0.026
heart morphogenesis	GO:0003007	178	0.026
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.026
cytoplasmic transport	GO:0016482	234	0.026
forebrain development	GO:0030900	302	0.025
protein tetramerization	GO:0051262	23	0.025
apoptotic signaling pathway	GO:0097190	306	0.025
purine ribonucleoside catabolic process	GO:0046130	205	0.024
cellular response to lipid	GO:0071396	145	0.024
multicellular organism growth	GO:0035264	161	0.024
regulation of apoptotic signaling pathway	GO:2001233	197	0.024
organophosphate catabolic process	GO:0046434	232	0.024
purine containing compound metabolic process	GO:0072521	311	0.024
muscle tissue development	GO:0060537	308	0.024
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.024
multicellular organismal homeostasis	GO:0048871	164	0.023
purine ribonucleotide metabolic process	GO:0009150	290	0.023
regulation of secretion	GO:0051046	274	0.022
striated muscle tissue development	GO:0014706	293	0.022
sensory perception	GO:0007600	245	0.022
small molecule biosynthetic process	GO:0044283	132	0.022
regulation of hormone levels	GO:0010817	211	0.022
fertilization	GO:0009566	127	0.021
positive regulation of cell death	GO:0010942	224	0.021
histone modification	GO:0016570	159	0.021
heterocycle catabolic process	GO:0046700	280	0.021
purine containing compound catabolic process	GO:0072523	213	0.021
alpha amino acid metabolic process	GO:1901605	59	0.021
aromatic compound catabolic process	GO:0019439	286	0.021
positive regulation of protein modification process	GO:0031401	299	0.021
peptidyl amino acid modification	GO:0018193	336	0.021
organonitrogen compound biosynthetic process	GO:1901566	192	0.021
blood vessel morphogenesis	GO:0048514	285	0.020
transmembrane transport	GO:0055085	412	0.020
ribonucleotide metabolic process	GO:0009259	291	0.020
neuronal action potential	GO:0019228	54	0.020
epidermis development	GO:0008544	187	0.020
lipid localization	GO:0010876	126	0.020
respiratory system development	GO:0060541	190	0.019
nitrogen compound transport	GO:0071705	271	0.019
chromatin modification	GO:0016568	187	0.019
regulation of membrane potential	GO:0042391	192	0.019
regulation of homeostatic process	GO:0032844	182	0.019
protein modification by small protein conjugation	GO:0032446	187	0.019
response to radiation	GO:0009314	165	0.019
skin development	GO:0043588	220	0.019
regulation of cellular response to stress	GO:0080135	159	0.019
transmission of nerve impulse	GO:0019226	76	0.018
nucleotide catabolic process	GO:0009166	217	0.018
cellular response to acid chemical	GO:0071229	68	0.018
anatomical structure homeostasis	GO:0060249	145	0.018
carbohydrate derivative catabolic process	GO:1901136	231	0.018
bmp signaling pathway	GO:0030509	93	0.018
organic acid biosynthetic process	GO:0016053	86	0.018
regulation of neuron differentiation	GO:0045664	281	0.017
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.017
purine nucleoside catabolic process	GO:0006152	205	0.017
protein modification by small protein conjugation or removal	GO:0070647	207	0.017
cation transport	GO:0006812	399	0.017
multicellular organismal signaling	GO:0035637	91	0.017
regulation of secretion by cell	GO:1903530	249	0.017
peptide secretion	GO:0002790	114	0.017
cellular response to dna damage stimulus	GO:0006974	207	0.017
macromolecule catabolic process	GO:0009057	281	0.017
purine nucleotide metabolic process	GO:0006163	302	0.017
intracellular protein transport	GO:0006886	204	0.017
protein ubiquitination	GO:0016567	171	0.016
positive regulation of apoptotic process	GO:0043065	217	0.016
alcohol metabolic process	GO:0006066	116	0.016
regulation of response to wounding	GO:1903034	189	0.015
posttranscriptional regulation of gene expression	GO:0010608	155	0.015
protein catabolic process	GO:0030163	221	0.015
cytokine production	GO:0001816	319	0.015
response to acid chemical	GO:0001101	111	0.015
purine nucleoside metabolic process	GO:0042278	241	0.015
amide transport	GO:0042886	138	0.015
purine ribonucleoside metabolic process	GO:0046128	241	0.015
angiogenesis	GO:0001525	201	0.015
nucleoside triphosphate metabolic process	GO:0009141	230	0.015
maintenance of location	GO:0051235	89	0.015
cardiac chamber morphogenesis	GO:0003206	93	0.015
regulation of cell motility	GO:2000145	236	0.015
action potential	GO:0001508	78	0.015
regulation of lipid metabolic process	GO:0019216	118	0.014
detection of stimulus	GO:0051606	84	0.014
covalent chromatin modification	GO:0016569	163	0.014
nucleoside catabolic process	GO:0009164	206	0.014
respiratory tube development	GO:0030323	167	0.014
glycosyl compound catabolic process	GO:1901658	206	0.014
purine ribonucleotide catabolic process	GO:0009154	208	0.014
nucleoside monophosphate metabolic process	GO:0009123	85	0.014
ribonucleoside catabolic process	GO:0042454	206	0.014
regulation of organelle organization	GO:0033043	289	0.014
rhythmic process	GO:0048511	174	0.014
ribonucleotide catabolic process	GO:0009261	208	0.014
lung development	GO:0030324	164	0.013
multicellular organismal aging	GO:0010259	24	0.013
regulation of cell activation	GO:0050865	289	0.013
cardiac ventricle development	GO:0003231	83	0.013
carboxylic acid biosynthetic process	GO:0046394	86	0.013
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.013
cardiocyte differentiation	GO:0035051	87	0.013
ras protein signal transduction	GO:0007265	77	0.013
steroid biosynthetic process	GO:0006694	47	0.013
organic hydroxy compound biosynthetic process	GO:1901617	77	0.013
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.013
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.013
cellular response to biotic stimulus	GO:0071216	92	0.013
actin cytoskeleton organization	GO:0030036	220	0.013
morphogenesis of a branching structure	GO:0001763	203	0.012
tissue homeostasis	GO:0001894	115	0.012
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.012
placenta development	GO:0001890	140	0.012
circulatory system process	GO:0003013	197	0.012
regulation of neuron death	GO:1901214	134	0.012
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.012
intrinsic apoptotic signaling pathway	GO:0097193	132	0.012
translational initiation	GO:0006413	24	0.012
negative regulation of molecular function	GO:0044092	258	0.012
renal system development	GO:0072001	225	0.012
detection of external stimulus	GO:0009581	61	0.012
inflammatory response	GO:0006954	244	0.012
purine nucleotide catabolic process	GO:0006195	211	0.012
reactive oxygen species metabolic process	GO:0072593	84	0.012
leukocyte proliferation	GO:0070661	172	0.012
cholesterol homeostasis	GO:0042632	44	0.012
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.012
regulation of vesicle mediated transport	GO:0060627	139	0.012
cellular homeostasis	GO:0019725	240	0.012
negative regulation of cellular protein metabolic process	GO:0032269	247	0.012
axon ensheathment	GO:0008366	76	0.012
negative regulation of protein phosphorylation	GO:0001933	126	0.011
coenzyme metabolic process	GO:0006732	52	0.011
ear development	GO:0043583	200	0.011
embryonic placenta development	GO:0001892	98	0.011
carbohydrate metabolic process	GO:0005975	230	0.011
cation transmembrane transport	GO:0098655	266	0.011
g protein coupled receptor signaling pathway	GO:0007186	243	0.011
gonad development	GO:0008406	141	0.011
cellular alcohol metabolic process	GO:0044107	3	0.011
regulation of cytokine production	GO:0001817	266	0.011
positive regulation of cholesterol homeostasis	GO:2000189	2	0.011
fatty acid biosynthetic process	GO:0006633	41	0.011
cofactor metabolic process	GO:0051186	80	0.011
extrinsic apoptotic signaling pathway	GO:0097191	126	0.011
regulation of inflammatory response	GO:0050727	147	0.011
peptide hormone secretion	GO:0030072	109	0.011
neuron death	GO:0070997	154	0.011
positive regulation of lymphocyte activation	GO:0051251	140	0.011
lipid homeostasis	GO:0055088	63	0.011
regulation of binding	GO:0051098	111	0.011
lymphocyte proliferation	GO:0046651	164	0.011
regulation of protein kinase activity	GO:0045859	232	0.011
protein localization to nucleus	GO:0034504	121	0.011
regulation of t cell activation	GO:0050863	170	0.010
myelination	GO:0042552	74	0.010
nucleocytoplasmic transport	GO:0006913	139	0.010
mapk cascade	GO:0000165	281	0.010
dna metabolic process	GO:0006259	303	0.010
positive regulation of mapk cascade	GO:0043410	170	0.010
negative regulation of cellular amine metabolic process	GO:0033239	1	0.010
cellular response to molecule of bacterial origin	GO:0071219	83	0.010
cell adhesion	GO:0007155	329	0.010
cell type specific apoptotic process	GO:0097285	268	0.010
regulation of fatty acid metabolic process	GO:0019217	28	0.010
metal ion homeostasis	GO:0055065	189	0.010
epithelial tube morphogenesis	GO:0060562	303	0.010
regulation of intracellular transport	GO:0032386	159	0.010
chemotaxis	GO:0006935	247	0.010
cardiac muscle cell differentiation	GO:0055007	69	0.010
nucleoside triphosphate catabolic process	GO:0009143	205	0.010
positive regulation of cell development	GO:0010720	237	0.010

Mpnd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.017
nervous system disease	DOID:863	0.017
disease of metabolism	DOID:0014667	0.016
inherited metabolic disorder	DOID:655	0.013

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