Mus musculus

207 known processes

Runx2

runt related transcription factor 2

(Aliases: Osf2,Cbfa-1,AML3,Cbfa1,Pebp2a1,Pebpa2a,LS3,Cbf,PEBP2aA)

Runx2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
skeletal system morphogenesisGO:00487052031.000
embryonic skeletal system morphogenesisGO:0048704911.000
embryonic skeletal system developmentGO:00487061200.999
retinal bipolar neuron differentiationGO:006004050.999
stem cell developmentGO:00488642190.998
neural crest cell migration involved in autonomic nervous system developmentGO:190116650.997
limb developmentGO:00601731660.996
embryonic organ morphogenesisGO:00485622760.995
skeletal system developmentGO:00015013560.993
osteoblast developmentGO:0002076170.990
sensory organ morphogenesisGO:00905962420.989
Fly
bone morphogenesisGO:0060349780.989
globus pallidus developmentGO:002175920.989
epithelial to mesenchymal transitionGO:0001837470.987
embryonic olfactory bulb interneuron precursor migrationGO:002183120.986
nodal signaling pathway involved in determination of left right asymmetryGO:003810720.984
cell proliferation involved in outflow tract morphogenesisGO:006132540.982
mesenchymal cell developmentGO:0014031930.982
limb morphogenesisGO:00351081490.981
chondrocyte differentiationGO:0002062720.981
appendage morphogenesisGO:00351071490.980
chondrocyte developmentGO:0002063240.979
mammary placode formationGO:006059640.975
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesisGO:007203940.974
carbon catabolite repression of transcription from rna polymerase ii promoterGO:000043710.972
mesenchymal cell differentiationGO:00487621070.971
mesenchyme developmentGO:00604851520.971
blood vessel morphogenesisGO:00485142850.970
Mouse
endochondral bone morphogenesisGO:0060350500.962
myeloid cell differentiationGO:00300992330.962
positive regulation of inner ear receptor cell differentiationGO:200098210.961
endodermal cell fate specificationGO:000171440.960
embryonic appendage morphogenesisGO:00351131260.960
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190016420.955
positive regulation of stem cell proliferationGO:2000648590.953
embryonic limb morphogenesisGO:00303261260.952
replacement ossificationGO:0036075260.950
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:190009420.950
embryonic skeletal joint developmentGO:0072498130.948
tooth mineralizationGO:003450590.945
epithelial tube morphogenesisGO:00605623030.943
positive regulation of cell motilityGO:20001471160.943
embryonic camera type eye developmentGO:0031076360.942
stem cell differentiationGO:00488632680.941
embryonic skeletal joint morphogenesisGO:0060272110.940
positive regulation of ossificationGO:0045778470.938
negative regulation of epithelial cell proliferationGO:0050680640.937
Mouse
regulation of cell motilityGO:20001452360.935
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080210.933
forelimb morphogenesisGO:0035136400.932
regionalizationGO:00030023370.931
Zebrafish
ossificationGO:00015032160.931
digestive tract developmentGO:00485651900.931
Fly
regulation of osteoblast differentiationGO:0045667670.929
forebrain generation of neuronsGO:0021872630.924
positive regulation of apoptotic processGO:00430652170.924
Mouse
myeloid leukocyte differentiationGO:00025731190.920
embryonic digit morphogenesisGO:0042733560.919
diencephalon developmentGO:0021536630.917
central nervous system neuron differentiationGO:00219531620.914
cellular response to growth factor stimulusGO:00713631970.914
telencephalon cell migrationGO:0022029550.912
forebrain cell migrationGO:0021885580.907
melanocyte differentiationGO:0030318250.906
regulation of skeletal muscle fiber developmentGO:0048742360.903
positive regulation of auditory receptor cell differentiationGO:004560910.902
regulation of stem cell differentiationGO:2000736500.899
tangential migration from the subventricular zone to the olfactory bulbGO:002202850.896
mesenchymal cell proliferation involved in ureter developmentGO:007219840.895
muscle cell developmentGO:00550011330.894
embryonic heart tube formationGO:000314410.891
neural crest formationGO:001402920.889
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152270.889
palate developmentGO:0060021760.884
bmp signaling pathwayGO:0030509930.882
positive regulation of osteoblast differentiationGO:0045669340.881
aorta morphogenesisGO:0035909220.881
hindlimb morphogenesisGO:0035137420.878
regulation of odontogenesisGO:0042481180.877
cartilage development involved in endochondral bone morphogenesisGO:0060351240.876
endodermal cell fate commitmentGO:0001711120.876
forebrain developmentGO:00309003020.876
regulation of leukocyte differentiationGO:19021051590.875
connective tissue developmentGO:00614481790.873
apoptotic process involved in outflow tract morphogenesisGO:000327520.871
regulation of mesenchymal cell proliferation involved in ureter developmentGO:007219930.866
camera type eye developmentGO:00430102660.866
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043640.865
regulation of myoblast differentiationGO:0045661290.861
mesonephros developmentGO:0001823970.858
cerebral cortex gabaergic interneuron differentiationGO:002189290.857
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325730.849
positive regulation of phospholipase activityGO:001051830.848
mesenchymal cell apoptotic process involved in nephron morphogenesisGO:190114540.843
auditory receptor cell fate determinationGO:004266830.840
neural tube closureGO:0001843900.838
leukocyte differentiationGO:00025213420.836
neuron projection guidanceGO:00974851410.834
Mouse Fly
positive regulation of epithelial to mesenchymal transitionGO:0010718130.834
regulation of ossificationGO:00302781120.818
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic processGO:200076310.812
tendon cell differentiationGO:003599040.811
stem cell maintenanceGO:00198271300.810
cerebral cortex neuron differentiationGO:0021895190.810
negative regulation of muscle cell differentiationGO:0051148330.808
ventricular zone neuroblast divisionGO:002184730.807
negative regulation of planar cell polarity pathway involved in pericardium morphogenesisGO:200016610.807
smoothened signaling pathway involved in dorsal ventral neural tube patterningGO:0060831120.805
regulation of chondrocyte differentiationGO:0032330330.800
bmp signaling pathway involved in heart developmentGO:006131220.797
regulation of cell cycleGO:00517262810.796
Mouse
odontogenesisGO:0042476780.793
skeletal muscle organ developmentGO:00605381630.792
neural crest cell migrationGO:0001755320.791
positive regulation of epithelial cell proliferationGO:0050679680.790
developmental maturationGO:00217001930.790
deltoid tuberosity developmentGO:003599330.786
cerebral cortex gabaergic interneuron migrationGO:002185360.784
positive regulation of epithelial cell proliferation involved in lung morphogenesisGO:006050130.778
embryonic hindlimb morphogenesisGO:0035116320.774
regulation of epithelial to mesenchymal transitionGO:0010717220.769
sensory perception of light stimulusGO:0050953540.768
planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:006135020.762
embryonic nail plate morphogenesisGO:003588030.761
digestive system developmentGO:00551232000.758
Fly
trachea formationGO:006044030.754
sinoatrial node cell differentiationGO:006092130.754
regulation of cell morphogenesis involved in differentiationGO:00107691510.752
pigmentationGO:0043473710.751
positive regulation of secondary heart field cardioblast proliferationGO:007251340.748
telencephalon developmentGO:00215371860.746
primary neural tube formationGO:0014020950.745
otic placode formationGO:004304910.743
positive regulation of transcription from rna polymerase ii promoter by glucoseGO:000043230.742
response to growth factorGO:00708481980.741
cell proliferation in hindbrainGO:0021534100.740
positive regulation of mesenchymal cell proliferation involved in ureter developmentGO:200072930.738
response to acid chemicalGO:00011011110.738
Mouse
regulation of planar cell polarity pathway involved in ventricular septum morphogenesisGO:200014810.737
regulation of endodermal cell fate specificationGO:004266320.735
left lung developmentGO:006045940.734
regulation of fat cell differentiationGO:0045598810.731
hindbrain tangential cell migrationGO:002193420.729
neural crest cell differentiationGO:0014033540.727
his purkinje system cell differentiationGO:006093220.726
biomineral tissue developmentGO:0031214640.724
epithelial cell developmentGO:00020641590.723
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.723
retina morphogenesis in camera type eyeGO:0060042450.717
negative regulation of striated muscle cell differentiationGO:0051154140.713
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesisGO:007204040.708
positive regulation of phospholipase c activityGO:001086320.698
positive regulation of neuron apoptotic processGO:0043525250.698
regulation of myotube differentiationGO:0010830620.694
bone developmentGO:00603481200.692
enamel mineralizationGO:007016670.685
heart field specificationGO:000312860.680
specification of organ positionGO:001015930.679
craniofacial suture morphogenesisGO:0097094100.679
regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:190121390.678
forebrain neuron differentiationGO:0021879520.675
mesodermal to mesenchymal transition involved in gastrulationGO:006080910.673
regulation of cell projection organizationGO:00313442060.665
regulation of heart morphogenesisGO:2000826220.656
endoderm formationGO:0001706200.650
visual perceptionGO:0007601520.646
regulation of cell migrationGO:00303342190.645
epithelial cell maturation involved in prostate gland developmentGO:006074340.640
cardiac neural crest cell migration involved in outflow tract morphogenesisGO:000325330.639
branching morphogenesis of an epithelial tubeGO:00487541590.638
t cell activationGO:00421102890.634
formation of primary germ layerGO:0001704770.629
cartilage morphogenesisGO:0060536110.627
negative regulation of stem cell maintenanceGO:190245540.619
positive regulation of cardioblast differentiationGO:005189130.618
pituitary gland developmentGO:0021983380.617
positive regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:190122840.613
tendon formationGO:003599240.612
cellular response to abiotic stimulusGO:0071214560.604
striated muscle tissue developmentGO:00147062930.604
negative regulation of cell proliferationGO:00082852960.604
Mouse
ear developmentGO:00435832000.603
regulation of glial cell differentiationGO:0045685410.601
activation of meiosisGO:009042740.598
respiratory system developmentGO:00605411900.597
embryonic forelimb morphogenesisGO:0035115320.597
positive regulation of cell deathGO:00109422240.597
Mouse Fly
ear morphogenesisGO:00424711180.597
locus ceruleus developmentGO:002170310.597
thyroid stimulating hormone secreting cell differentiationGO:006012940.596
regulation of cartilage developmentGO:0061035440.591
negative regulation of cardiac chamber morphogenesisGO:190122020.591
metanephric nephron tubule formationGO:007228940.590
negative regulation of immature t cell proliferationGO:003308730.589
hemangioblast cell differentiationGO:006021710.589
atrial ventricular junction remodelingGO:000329420.586
regulation of planar cell polarity pathway involved in outflow tract morphogenesisGO:200016310.584
regulation of synaptic growth at neuromuscular junctionGO:000858240.583
reactive oxygen species metabolic processGO:0072593840.581
metanephric capsule specificationGO:007226710.580
gastrulationGO:00073691160.580
Fly
leukocyte proliferationGO:00706611720.580
formation of radial glial scaffoldsGO:002194340.577
telencephalon regionalizationGO:0021978140.576
regulation of cellular amine metabolic processGO:0033238200.575
lung developmentGO:00303241640.574
keratinocyte proliferationGO:0043616210.573
neuroepithelial cell differentiationGO:0060563370.573
axial mesodermal cell fate commitmentGO:004832210.572
skeletal muscle fiber developmentGO:0048741580.567
germ cell developmentGO:00072811850.567
cytokine mediated signaling pathwayGO:00192211150.559
negative regulation of osteoblast differentiationGO:0045668300.558
positive regulation of mesenchymal cell proliferationGO:0002053330.556
inflammatory responseGO:00069542440.554
commitment of neuronal cell to specific neuron type in forebrainGO:002190270.553
cartilage condensationGO:0001502180.550
noradrenergic neuron developmentGO:000335830.546
mammary gland morphogenesisGO:0060443540.545
cellular protein catabolic processGO:00442571550.543
regulation of reactive oxygen species metabolic processGO:2000377400.540
glial cell differentiationGO:00100011310.538
muscle fiber developmentGO:0048747760.536
face morphogenesisGO:0060325290.535
angiogenesisGO:00015252010.534
Mouse
striated muscle cell developmentGO:00550021250.532
regulation of feeding behaviorGO:006025930.532
retina development in camera type eyeGO:00600411190.530
positive regulation of bmp signaling pathwayGO:0030513230.529
body morphogenesisGO:0010171450.526
trophectodermal cellular morphogenesisGO:000183130.523
negative regulation of gastrulationGO:200054230.522
muscle cell proliferationGO:0033002520.520
mitral valve morphogenesisGO:000318340.517
positive regulation of stem cell differentiationGO:2000738230.513
ovulation cycleGO:0042698590.512
regulation of skeletal muscle fiber differentiationGO:190280930.510
eye photoreceptor cell developmentGO:0042462310.509
Fly
oculomotor nerve morphogenesisGO:002162220.508
positive regulation of fat cell differentiationGO:0045600320.506
negative regulation of lymphocyte differentiationGO:0045620320.505
negative regulation of apoptotic process involved in outflow tract morphogenesisGO:190225720.504
pattern specification involved in metanephros developmentGO:007226840.494
skin morphogenesisGO:0043589380.493
Mouse
rhythmic processGO:00485111740.491
oocyte differentiationGO:0009994350.485
cell maturationGO:00484691270.481
positive regulation of endothelial cell proliferationGO:0001938170.480
stem cell proliferationGO:00720891170.479
heart valve morphogenesisGO:0003179210.478
negative regulation of cell fate specificationGO:000999640.478
face developmentGO:0060324380.478
amine metabolic processGO:0009308450.477
carbon catabolite activation of transcriptionGO:004599140.476
response to organic cyclic compoundGO:00140701980.475
neural tube patterningGO:0021532430.467
regulation of mapk cascadeGO:00434082480.467
sinoatrial node cell developmentGO:006093130.466
positive regulation of apoptotic signaling pathwayGO:2001235950.460
Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.460
covalent chromatin modificationGO:00165691630.459
negative regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formationGO:006082910.459
regulation of peptide secretionGO:0002791770.458
trachea cartilage morphogenesisGO:006053540.457
cell divisionGO:00513011200.456
regulation of muscle tissue developmentGO:1901861970.455
pyramidal neuron migrationGO:002185210.453
lymphocyte differentiationGO:00300982420.449
lipid biosynthetic processGO:00086101790.446
positive regulation of cartilage developmentGO:0061036180.445
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.443
hair cycleGO:0042633900.443
Mouse
metanephric mesenchyme morphogenesisGO:007213340.442
mesoderm formationGO:0001707620.442
response to nutrient levelsGO:00316671090.439
cellular response to inorganic substanceGO:0071241370.435
positive regulation of programmed cell deathGO:00430682180.432
Mouse Fly
protein modification by small protein conjugation or removalGO:00706472070.430
fat cell differentiationGO:00454441600.430
pigment cell differentiationGO:0050931270.429
chromatin modificationGO:00165681870.426
anterior commissure morphogenesisGO:002196060.426
negative regulation of molecular functionGO:00440922580.425
lung epithelium developmentGO:0060428370.422
positive regulation of tongue muscle cell differentiationGO:200103720.422
cellular amine metabolic processGO:0044106440.421
pancreatic pp cell fate commitmentGO:000332920.420
positive regulation of odontogenesisGO:004248240.419
floor plate morphogenesisGO:003350530.419
sensory perceptionGO:00076002450.418
negative regulation of apoptotic process involved in morphogenesisGO:190233860.417
regulation of erk1 and erk2 cascadeGO:0070372710.412
cellular amino acid metabolic processGO:00065201030.408
negative regulation of chondrocyte differentiationGO:0032331130.407
osteoclast differentiationGO:0030316620.406
positive regulation of cell cycleGO:0045787920.406
positive regulation of glial cell differentiationGO:0045687210.403
regulation of lipase activityGO:0060191150.398
ameboidal type cell migrationGO:00016671280.398
positive regulation of vascular wound healingGO:003547010.395
positive regulation of hh target transcription factor activityGO:000722830.392
semicircular canal morphogenesisGO:004875270.391
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.390
Mouse
cerebral cortex developmentGO:0021987860.387
cell differentiation involved in kidney developmentGO:0061005330.387
cardiac right ventricle formationGO:000321930.386
neural nucleus developmentGO:0048857220.386
cardiac muscle cell developmentGO:0055013390.384
cranial suture morphogenesisGO:006036380.384
cellular response to cytokine stimulusGO:00713451890.380
negative regulation of planar cell polarity pathway involved in heart morphogenesisGO:200016010.379
endocardial cushion formationGO:0003272130.379
endocardial cushion to mesenchymal transition involved in heart valve formationGO:000319940.378
regulation of mesenchymal cell proliferationGO:0010464370.378
corticotropin hormone secreting cell differentiationGO:006012830.376
positive regulation of cell migrationGO:00303351090.376
positive regulation of wnt signaling pathwayGO:0030177450.372
regulation of lymphocyte activationGO:00512492400.368
oocyte axis specificationGO:000730920.368
cytokine productionGO:00018163190.367
Mouse
cellular ketone metabolic processGO:0042180840.367
cerebral cortex tangential migrationGO:002180070.364
regulation of transcription involved in primary germ layer cell fate commitmentGO:006079620.360
prostate epithelial cord elongationGO:006052330.359
erk1 and erk2 cascadeGO:0070371770.359
cell proliferation in external granule layerGO:0021924100.359
appendage developmentGO:00487361660.359
epithelial cell proliferation involved in prostate gland developmentGO:0060767110.358
calcium ion transportGO:00068161590.356
regulation of cell proliferation involved in heart morphogenesisGO:2000136150.355
atrioventricular bundle cell differentiationGO:000316710.353
eye photoreceptor cell differentiationGO:0001754410.353
Fly
myotube differentiationGO:00149021050.353
positive regulation of bone mineralizationGO:0030501120.352
jak stat cascadeGO:0007259420.350
camera type eye photoreceptor cell differentiationGO:0060219150.349
oogenesisGO:0048477560.343
tube formationGO:00351481400.343
morphogenesis of embryonic epitheliumGO:00163311590.341
regulation of lymphocyte differentiationGO:00456191070.340
negative regulation of protein metabolic processGO:00512482820.337
trophectodermal cell differentiationGO:0001829210.334
regulation of apoptotic process involved in morphogenesisGO:1902337100.333
circulatory system processGO:00030131970.331
cerebral cortex cell migrationGO:0021795440.331
wnt signaling pathway involved in forebrain neuroblast divisionGO:002187420.330
germ line stem cell divisionGO:004207820.327
medulla oblongata developmentGO:002155030.324
cell fate specificationGO:0001708720.324
organic hydroxy compound metabolic processGO:19016152030.324
mammary gland bud formationGO:006061520.323
cellular macromolecule catabolic processGO:00442652060.322
noradrenergic neuron differentiationGO:000335760.322
multicellular organismal homeostasisGO:00488711640.321
c21 steroid hormone biosynthetic processGO:000670030.321
negative regulation of t cell proliferationGO:0042130380.321
oocyte constructionGO:000730820.320
negative regulation of transcription from rna polymerase ii promoter by glucoseGO:000043310.317
regulation of cardiac chamber formationGO:190121010.317
response to amino acidGO:0043200370.317
regulation of stem cell proliferationGO:0072091780.316
wound healing spreading of cellsGO:004431980.315
negative regulation of endodermal cell differentiationGO:190322510.314
tissue homeostasisGO:00018941150.312
muscle tissue developmentGO:00605373080.309
regulation of canonical wnt signaling pathwayGO:0060828820.309
forebrain radial glial cell differentiationGO:002186140.308
kidney vasculature morphogenesisGO:006143970.308
oocyte developmentGO:0048599330.307
ectodermal placode morphogenesisGO:0071697160.305
spermatid differentiationGO:00485151150.301
alpha beta t cell activationGO:0046631910.300
positive regulation of gliogenesisGO:0014015270.299
mammary gland epithelium developmentGO:0061180650.298
positive regulation of mesenchymal cell apoptotic processGO:200105530.297
gliogenesisGO:00420631410.297
regulation of sequence specific dna binding transcription factor activityGO:00510901060.297
left lung morphogenesisGO:006046030.296
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesisGO:200014910.295
regulation of bmp signaling pathwayGO:0030510600.295
neuron migrationGO:00017641220.295
regulation of stem cell maintenanceGO:2000036170.294
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:200016210.293
generation of precursor metabolites and energyGO:00060911030.292
epidermal growth factor receptor signaling pathwayGO:0007173280.292
prostate gland morphogenesisGO:0060512320.292
cellular response to external stimulusGO:0071496880.292
regulation of planar cell polarity pathway involved in neural tube closureGO:200016710.291
neural tube formationGO:00018411080.286
maternal placenta developmentGO:0001893200.286
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisGO:007210830.286
proteoglycan metabolic processGO:0006029380.285
regulation of cell divisionGO:0051302760.285
regulation of chromatin modificationGO:1903308570.284
embryonic epithelial tube formationGO:00018381300.283
lung epithelial cell differentiationGO:0060487290.282
carbon catabolite repression of transcriptionGO:004501310.282
negative regulation of kinase activityGO:0033673810.281
neural tube developmentGO:00219151600.281
cardiac muscle tissue developmentGO:00487381300.280
organ growthGO:00352651170.279
cell differentiation involved in embryonic placenta developmentGO:0060706260.279
regulation of neuron projection developmentGO:00109751690.277
regulation of myeloid leukocyte differentiationGO:0002761580.277
middle ear morphogenesisGO:0042474230.276
cellular response to amino acid stimulusGO:0071230290.274
spinal cord oligodendrocyte cell fate specificationGO:002153030.273
cerebellar granule cell precursor proliferationGO:0021930100.272
olfactory lobe developmentGO:0021988320.271
cellular response to mechanical stimulusGO:007126070.271
metanephric glomerulus vasculature morphogenesisGO:007227630.270
positive regulation of transcription by glucoseGO:004601630.270
positive regulation of neuron projection regenerationGO:007057220.268
cell proliferation in forebrainGO:0021846300.268
regulation of tongue muscle cell differentiationGO:200103520.267
ribose phosphate metabolic processGO:00196932910.267
smooth muscle tissue developmentGO:0048745220.266
epidermis developmentGO:00085441870.264
Mouse
axonogenesisGO:00074092740.264
Mouse Fly
cerebral cortex gabaergic interneuron fate commitmentGO:002189320.264
smad protein signal transductionGO:0060395210.263
regulation of cellular amino acid metabolic processGO:000652150.263
carbohydrate catabolic processGO:0016052320.262
granulosa cell differentiationGO:006001410.262
inner ear morphogenesisGO:00424721010.261
mitochondrion distributionGO:004831140.261
forebrain regionalizationGO:0021871250.261
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferationGO:002193840.261
roof plate formationGO:002150910.259
glomerulus vasculature morphogenesisGO:007210360.259
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesisGO:200016410.256
negative regulation of transcription by glucoseGO:004501410.255
skeletal muscle cell differentiationGO:0035914660.255
growth plate cartilage developmentGO:0003417140.250
carbon catabolite regulation of transcriptionGO:004599040.249
neural crest cell developmentGO:0014032480.248
vagus nerve morphogenesisGO:002164420.247
regulation of mesenchymal cell apoptotic processGO:2001053140.246
regulation of neuron differentiationGO:00456642810.246
positive regulation of chondrocyte differentiationGO:0032332130.246
vascular wound healingGO:006104230.245
negative regulation of keratinocyte differentiationGO:004561740.245
canonical wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart developmentGO:006131010.243
positive regulation of alpha beta t cell differentiationGO:0046638280.243
mammary gland duct morphogenesisGO:0060603380.243
negative regulation of cholesterol transportGO:003237540.243
mesenchymal cell differentiation involved in lung developmentGO:006091520.243
regulation of planar cell polarity pathway involved in heart morphogenesisGO:200015910.242
regulation of skeletal muscle cell differentiationGO:2001014110.240
axis elongationGO:0003401300.238
cardiac left ventricle formationGO:000321810.238
regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:200016110.238
regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080010.236
regulation of b cell activationGO:0050864810.235
smooth muscle cell migrationGO:0014909100.234
transmembrane transportGO:00550854120.231
positive regulation of canonical wnt signaling pathwayGO:0090263290.230
regulation of cytokine productionGO:00018172660.229
cardiocyte differentiationGO:0035051870.229
epithelial cell differentiation involved in kidney developmentGO:0035850230.228
tube closureGO:0060606910.227
positive regulation of dna templated transcription elongationGO:003278620.226
mesangial cell differentiationGO:007200740.226
hair follicle morphogenesisGO:0031069290.225
Mouse
synaptic transmissionGO:00072683290.225
pronephric field specificationGO:003900320.224
regulation of phospholipase c activityGO:190027430.224
positive regulation of cardiac muscle cell proliferationGO:0060045150.223
second messenger mediated signalingGO:0019932730.222
olfactory bulb developmentGO:0021772300.221
positive regulation of branching involved in lung morphogenesisGO:006104740.221
intestinal epithelial structure maintenanceGO:006072940.221
lateral line system developmentGO:004892510.220
positive regulation of skeletal muscle fiber differentiationGO:190281120.220
negative regulation of cell cycleGO:00457861230.220
Mouse
molting cycleGO:0042303900.220
Mouse
cerebral cortex gabaergic interneuron developmentGO:002189460.220
lung cell differentiationGO:0060479300.219
cardiac chamber developmentGO:00032051080.219
cellular response to fluid shear stressGO:007149840.218
negative regulation of wnt signaling pathway involved in heart developmentGO:000330840.218
chromatin organizationGO:00063252060.217
embryonic placenta developmentGO:0001892980.217
mesodermal cell fate commitmentGO:0001710170.216
thalamus developmentGO:0021794110.215
defense response to other organismGO:00985421970.213
blood circulationGO:00080151950.212
astrocyte fate commitmentGO:006001840.211
regulation of smooth muscle cell differentiationGO:005115090.211
histone modificationGO:00165701590.211
mesoderm developmentGO:00074981000.211

Runx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.998
Human
musculoskeletal system diseaseDOID:1700.998
Human
connective tissue diseaseDOID:6500.998
Human
bone diseaseDOID:008000100.978
Human
bone remodeling diseaseDOID:008000500.767
bone development diseaseDOID:008000600.469
Human
dysostosisDOID:193400.469
osteosclerosisDOID:425400.277