Mus musculus

19 known processes

Pcbd1

pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1

(Aliases: Pcbd,Dcoh)

Pcbd1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.272
small molecule biosynthetic processGO:00442831320.136
amine metabolic processGO:0009308450.127
lipid biosynthetic processGO:00086101790.114
steroid metabolic processGO:00082021190.112
cellular modified amino acid metabolic processGO:0006575630.105
cellular ketone metabolic processGO:0042180840.100
organic hydroxy compound metabolic processGO:19016152030.100
cellular amine metabolic processGO:0044106440.097
oxidation reduction processGO:00551143420.096
monocarboxylic acid metabolic processGO:00327871910.093
organic acid biosynthetic processGO:0016053860.091
regulation of cellular amine metabolic processGO:0033238200.090
cellular lipid metabolic processGO:00442553230.088
positive regulation of cellular amino acid metabolic processGO:004576430.077
sulfur compound metabolic processGO:00067901000.076
alcohol metabolic processGO:00060661160.076
regulation of cellular ketone metabolic processGO:0010565660.075
regulation of cellular amino acid metabolic processGO:000652150.075
positive regulation of cellular amine metabolic processGO:003324050.070
glutathione metabolic processGO:0006749160.065
sterol metabolic processGO:0016125580.062
carboxylic acid biosynthetic processGO:0046394860.062
spermatogenesisGO:00072832840.056
organic anion transportGO:00157111370.056
carboxylic acid transportGO:00469421000.051
fatty acid metabolic processGO:00066311210.049
response to organonitrogen compoundGO:00102432460.049
response to organic cyclic compoundGO:00140701980.047
nitrogen compound transportGO:00717052710.046
alpha amino acid metabolic processGO:1901605590.045
organonitrogen compound biosynthetic processGO:19015661920.045
organic acid transportGO:00158491010.043
cation transportGO:00068123990.042
organic cyclic compound catabolic processGO:19013612950.041
acetate metabolic processGO:000608310.041
xenobiotic catabolic processGO:004217810.040
transmembrane transportGO:00550854120.040
cholesterol metabolic processGO:0008203560.038
cytokine productionGO:00018163190.037
organonitrogen compound catabolic processGO:19015652640.037
dna metabolic processGO:00062593030.036
male gamete generationGO:00482322850.035
monosaccharide metabolic processGO:00059961060.035
negative regulation of protein metabolic processGO:00512482820.034
peptidyl amino acid modificationGO:00181933360.034
cofactor metabolic processGO:0051186800.033
regulation of membrane potentialGO:00423911920.032
cellular nitrogen compound catabolic processGO:00442702800.032
nucleoside phosphate metabolic processGO:00067533380.031
epidermis developmentGO:00085441870.031
response to acid chemicalGO:00011011110.030
negative regulation of cell proliferationGO:00082852960.030
anion transportGO:00068201770.030
glycerolipid metabolic processGO:00464861220.029
regulation of secretionGO:00510462740.029
skin developmentGO:00435882200.029
lipid transportGO:0006869980.029
carbohydrate derivative biosynthetic processGO:19011371830.028
regulation of protein kinase activityGO:00458592320.028
monocarboxylic acid biosynthetic processGO:0072330610.028
cellular alcohol metabolic processGO:004410730.028
placenta developmentGO:00018901400.028
regulation of secretion by cellGO:19035302490.028
regulation of hormone levelsGO:00108172110.028
regulation of cell activationGO:00508652890.027
lipid localizationGO:00108761260.027
positive regulation of protein phosphorylationGO:00019342420.027
polyamine catabolic processGO:000659820.027
muscle cell differentiationGO:00426922610.027
Worm
ion transmembrane transportGO:00342203610.027
apoptotic signaling pathwayGO:00971903060.027
cellular response to lipidGO:00713961450.027
nucleobase containing small molecule metabolic processGO:00550863520.027
nucleotide metabolic processGO:00091173320.026
aromatic compound catabolic processGO:00194392860.026
purine ribonucleotide metabolic processGO:00091502900.026
response to oxidative stressGO:00069791230.026
steroid biosynthetic processGO:0006694470.026
cell type specific apoptotic processGO:00972852680.026
skeletal system developmentGO:00015013560.026
carbohydrate metabolic processGO:00059752300.025
cellular amide metabolic processGO:0043603580.025
positive regulation of protein modification processGO:00314012990.025
carbohydrate homeostasisGO:00335001280.025
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.025
blood circulationGO:00080151950.025
small gtpase mediated signal transductionGO:0007264970.025
protein maturationGO:00516041760.024
organic hydroxy compound transportGO:0015850930.024
renal system developmentGO:00720012250.024
organic hydroxy compound biosynthetic processGO:1901617770.024
regulation of anatomical structure sizeGO:00900661780.024
circulatory system processGO:00030131970.024
cell adhesionGO:00071553290.024
regulation of organelle organizationGO:00330432890.024
response to nutrient levelsGO:00316671090.024
purine ribonucleoside metabolic processGO:00461282410.023
regulation of kinase activityGO:00435492490.023
intracellular protein transportGO:00068862040.023
multicellular organismal homeostasisGO:00488711640.023
nadph regenerationGO:000674020.023
multicellular organismal signalingGO:0035637910.023
sensory perceptionGO:00076002450.023
regulation of hydrolase activityGO:00513362460.023
wnt signaling pathwayGO:00160551880.023
cellular amino acid biosynthetic processGO:0008652220.023
glucose metabolic processGO:0006006920.023
negative regulation of molecular functionGO:00440922580.023
chromatin organizationGO:00063252060.023
ribonucleoside metabolic processGO:00091192450.023
regulation of system processGO:00440572000.023
hexose metabolic processGO:0019318980.022
heterocycle catabolic processGO:00467002800.022
cellular response to extracellular stimulusGO:0031668810.022
cellular homeostasisGO:00197252400.022
ribose phosphate metabolic processGO:00196932910.022
nucleoside metabolic processGO:00091162460.022
striated muscle tissue developmentGO:00147062930.022
gland developmentGO:00487323300.022
epithelial tube morphogenesisGO:00605623030.022
chromatin modificationGO:00165681870.022
regulation of response to woundingGO:19030341890.022
cation transmembrane transportGO:00986552660.022
purine containing compound metabolic processGO:00725213110.022
fatty acid biosynthetic processGO:0006633410.022
lymphocyte proliferationGO:00466511640.021
mapk cascadeGO:00001652810.021
anatomical structure homeostasisGO:00602491450.021
hormone metabolic processGO:0042445860.021
negative regulation of phosphorylationGO:00423261660.021
muscle tissue developmentGO:00605373080.021
rho protein signal transductionGO:0007266320.021
regulation of cell motilityGO:20001452360.021
purine nucleoside metabolic processGO:00422782410.021
positive regulation of protein kinase activityGO:00458601440.021
embryonic organ morphogenesisGO:00485622760.020
negative regulation of phosphate metabolic processGO:00459361840.020
regulation of transferase activityGO:00513382630.020
negative regulation of cellular amine metabolic processGO:003323910.020
negative regulation of cellular protein metabolic processGO:00322692470.020
ribonucleoside triphosphate metabolic processGO:00091992200.020
organophosphate catabolic processGO:00464342320.020
leukocyte proliferationGO:00706611720.020
cytoplasmic transportGO:00164822340.020
divalent inorganic cation transportGO:00725111780.020
nitrobenzene metabolic processGO:001891610.020
response to lipopolysaccharideGO:00324961280.020
purine ribonucleoside catabolic processGO:00461302050.020
regulation of neuron differentiationGO:00456642810.020
urogenital system developmentGO:00016552610.020
macromolecule catabolic processGO:00090572810.020
sensory organ morphogenesisGO:00905962420.020
regulation of cell cycleGO:00517262810.019
response to drugGO:0042493750.019
ras protein signal transductionGO:0007265770.019
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.019
positive regulation of programmed cell deathGO:00430682180.019
morphogenesis of a branching epitheliumGO:00611381930.019
regulation of protein localizationGO:00328802310.019
dephosphorylationGO:00163111290.019
glucose homeostasisGO:00425931280.019
small molecule catabolic processGO:0044282710.019
cellular response to hormone stimulusGO:00328701500.019
locomotory behaviorGO:00076261950.019
membrane organizationGO:00610242450.019
regulation of ion transportGO:00432692150.019
purine nucleotide metabolic processGO:00061633020.019
methylationGO:00322591340.019
cellular alcohol biosynthetic processGO:004410830.019
ribonucleotide metabolic processGO:00092592910.019
alpha amino acid biosynthetic processGO:1901607150.019
peptide metabolic processGO:0006518460.019
response to inorganic substanceGO:0010035960.019
positive regulation of cell deathGO:00109422240.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
regulation of cellular response to stressGO:00801351590.019
regulation of cellular catabolic processGO:00313292420.019
negative regulation of growthGO:0045926990.019
kidney developmentGO:00018222130.019
purine ribonucleotide catabolic processGO:00091542080.018
camera type eye developmentGO:00430102660.018
regulation of peptide transportGO:0090087910.018
posttranscriptional regulation of gene expressionGO:00106081550.018
nucleoside phosphate catabolic processGO:19012922220.018
glycoprotein metabolic processGO:00091001160.018
regulation of lymphocyte activationGO:00512492400.018
negative regulation of cellular amino acid metabolic processGO:004576300.018
epithelial cell developmentGO:00020641590.018
myeloid cell differentiationGO:00300992330.018
positive regulation of nervous system developmentGO:00519622210.018
cellular response to organonitrogen compoundGO:00714171450.018
regulation of establishment of protein localizationGO:00702011810.018
action potentialGO:0001508780.018
neutral lipid metabolic processGO:0006638570.018
multicellular organism growthGO:00352641610.018
positive regulation of apoptotic processGO:00430652170.018
response to extracellular stimulusGO:00099911270.017
response to peptide hormoneGO:00434341270.017
development of primary sexual characteristicsGO:00451371430.017
response to monosaccharideGO:0034284670.017
response to peptideGO:19016521360.017
carboxylic acid catabolic processGO:0046395510.017
regulation of cytokine productionGO:00018172660.017
digestive system developmentGO:00551232000.017
peptide secretionGO:00027901140.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
regulation of body fluid levelsGO:00508781620.017
cellular amino acid catabolic processGO:0009063250.017
cellular response to external stimulusGO:0071496880.017
transmission of nerve impulseGO:0019226760.017
glycoprotein biosynthetic processGO:0009101890.017
response to molecule of bacterial originGO:00022371430.017
gonad developmentGO:00084061410.017
blood vessel morphogenesisGO:00485142850.017
response to oxygen levelsGO:0070482620.017
cell growthGO:00160491300.016
reactive oxygen species metabolic processGO:0072593840.016
peptide transportGO:00158331330.016
peptide hormone secretionGO:00300721090.016
regulation of apoptotic signaling pathwayGO:20012331970.016
epithelial cell proliferationGO:00506731740.016
t cell activationGO:00421102890.016
cellular chemical homeostasisGO:00550822150.016
amide transportGO:00428861380.016
cell fate commitmentGO:00451652100.016
mitotic cell cycleGO:00002781950.016
rhythmic processGO:00485111740.016
carbohydrate derivative catabolic processGO:19011362310.016
branching morphogenesis of an epithelial tubeGO:00487541590.016
nucleoside triphosphate metabolic processGO:00091412300.016
morphogenesis of a branching structureGO:00017632030.016
regulation of cellular component biogenesisGO:00440871810.016
carbohydrate biosynthetic processGO:0016051740.016
ear developmentGO:00435832000.016
cation homeostasisGO:00550802120.016
protein processingGO:00164851630.016
positive regulation of transferase activityGO:00513471670.016
positive regulation of neuron differentiationGO:00456661410.016
l ascorbic acid metabolic processGO:001985240.016
protein localization to membraneGO:00726571080.016
cofactor biosynthetic processGO:0051188410.016
maintenance of locationGO:0051235890.016
vitamin metabolic processGO:0006766230.016
tissue homeostasisGO:00018941150.016
glycosyl compound catabolic processGO:19016582060.015
heart processGO:0003015940.015
guanosine containing compound catabolic processGO:19010691440.015
positive regulation of cellular catabolic processGO:00313311480.015
nucleotide catabolic processGO:00091662170.015
axonogenesisGO:00074092740.015
regulation of leukocyte proliferationGO:00706631210.015
muscle system processGO:00030121410.015
glycosyl compound metabolic processGO:19016572460.015
protein catabolic processGO:00301632210.015
negative regulation of cell developmentGO:00107211690.015
cellular response to peptideGO:1901653920.015
stem cell differentiationGO:00488632680.015
ossificationGO:00015032160.015
hormone secretionGO:00468791280.015
cellular macromolecule catabolic processGO:00442652060.015
progesterone metabolic processGO:004244840.015
leukocyte differentiationGO:00025213420.015
regulation of cell projection organizationGO:00313442060.015
cellular response to insulin stimulusGO:0032869780.015
monocarboxylic acid transportGO:0015718440.015
neuronal action potentialGO:0019228540.015
positive regulation of hydrolase activityGO:00513451480.015
divalent metal ion transportGO:00708381720.015
chemotaxisGO:00069352470.015
lipoprotein metabolic processGO:0042157430.015
negative regulation of cellular component organizationGO:00511291940.015
ribonucleoside catabolic processGO:00424542060.015
regulation of defense responseGO:00313472330.015
regulation of protein serine threonine kinase activityGO:00719001570.014
regulation of peptide hormone secretionGO:0090276750.014
regulation of proteolysisGO:00301621640.014
developmental growth involved in morphogenesisGO:00605601380.014
ear morphogenesisGO:00424711180.014
negative regulation of phosphorus metabolic processGO:00105631840.014
regulation of mapk cascadeGO:00434082480.014
cellular ion homeostasisGO:00068731650.014
organic acid catabolic processGO:0016054510.014
liver developmentGO:0001889660.014
cellular response to organic cyclic compoundGO:0071407870.014
positive regulation of mapk cascadeGO:00434101700.014
appendage developmentGO:00487361660.014
regulation of neuron projection developmentGO:00109751690.014
regulation of lymphocyte proliferationGO:00506701170.014
defense response to other organismGO:00985421970.014
nucleoside triphosphate catabolic processGO:00091432050.014
cellular response to dna damage stimulusGO:00069742070.014
purine nucleoside catabolic processGO:00061522050.014
immune effector processGO:00022523210.014
inflammatory responseGO:00069542440.014
tissue remodelingGO:00487711020.014
nucleoside monophosphate metabolic processGO:0009123850.014
insulin secretionGO:0030073890.014
protein targetingGO:00066051430.014
embryonic limb morphogenesisGO:00303261260.014
nucleocytoplasmic transportGO:00069131390.014
regulation of intracellular transportGO:00323861590.014
adult behaviorGO:00305341350.014
regulation of inflammatory responseGO:00507271470.014
actin cytoskeleton organizationGO:00300362200.014
Worm
positive regulation of reactive oxygen species metabolic processGO:2000379110.014
organ growthGO:00352651170.013
stem cell developmentGO:00488642190.013
negative regulation of immune system processGO:00026832090.013
limb developmentGO:00601731660.013
cellular response to peptide hormone stimulusGO:0071375920.013
regulation of peptidase activityGO:0052547960.013
purine ribonucleoside triphosphate catabolic processGO:00092071990.013
regulation of transmembrane transportGO:00347621280.013
nucleoside catabolic processGO:00091642060.013
glucose transportGO:0015758560.013
negative regulation of intracellular signal transductionGO:19025321670.013
nephron developmentGO:00720061090.013
nuclear transportGO:00511691390.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
limb morphogenesisGO:00351081490.013
homeostasis of number of cellsGO:00488722100.013
inorganic cation transmembrane transportGO:00986622070.013
developmental maturationGO:00217001930.013
inter male aggressive behaviorGO:000212130.013
cellular response to biotic stimulusGO:0071216920.013
positive regulation of cell developmentGO:00107202370.013
regulation of cellular carbohydrate metabolic processGO:0010675750.013
digestive tract developmentGO:00485651900.013
monosaccharide transportGO:0015749580.013
regulation of cell growthGO:0001558910.013
hematopoietic progenitor cell differentiationGO:00022441430.013
cellular carbohydrate metabolic processGO:00442621190.013
endomembrane system organizationGO:00102561470.013
activation of immune responseGO:00022531380.013
organelle assemblyGO:00709251770.013
Worm
hepaticobiliary system developmentGO:0061008670.013
compound eye developmentGO:004874910.013
coenzyme metabolic processGO:0006732520.013
establishment of blood nerve barrierGO:000806530.013
protein ubiquitinationGO:00165671710.013
fat cell differentiationGO:00454441600.013
regulation of purine nucleotide metabolic processGO:19005421690.013
regulation of protein transportGO:00512231630.013
regulation of homeostatic processGO:00328441820.012
cell substrate adhesionGO:00315891300.012
nuclear divisionGO:00002801580.012
muscle contractionGO:00069361010.012
carbohydrate transportGO:0008643620.012
protein modification by small protein conjugation or removalGO:00706472070.012
protein modification by small protein conjugationGO:00324461870.012
response to insulinGO:00328681000.012
regulation of hormone secretionGO:0046883880.012
terpenoid metabolic processGO:0006721250.012
forebrain developmentGO:00309003020.012
g protein coupled receptor signaling pathwayGO:00071862430.012
response to light stimulusGO:00094161350.012
myosin filament assemblyGO:003103420.012
Worm
regulation of chloride transportGO:200122520.012
multi multicellular organism processGO:00447061090.012
bile acid and bile salt transportGO:001572150.012
regulation of protein complex assemblyGO:0043254830.012
response to radiationGO:00093141650.012
wound healingGO:00420601570.012
rna processingGO:00063961050.012
kidney epithelium developmentGO:00720731210.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
inner ear morphogenesisGO:00424721010.012
organelle fissionGO:00482851700.012
positive regulation of steroid biosynthetic processGO:001089340.012
purine containing compound catabolic processGO:00725232130.012
cellular response to starvationGO:0009267570.012
inorganic ion transmembrane transportGO:00986602340.012
negative regulation of lymphocyte activationGO:0051250910.012
positive regulation of macroautophagyGO:001623930.012
response to starvationGO:0042594650.012
acylglycerol metabolic processGO:0006639550.012
regulation of leukocyte differentiationGO:19021051590.012
regulation of cell morphogenesis involved in differentiationGO:00107691510.012
tube formationGO:00351481400.012
fat soluble vitamin biosynthetic processGO:004236240.012
regulation of lipid metabolic processGO:00192161180.012
glial cell differentiationGO:00100011310.012
appendage morphogenesisGO:00351071490.012
macromolecule glycosylationGO:0043413550.012
ethanol metabolic processGO:000606730.012
t cell proliferationGO:00420981200.012
positive regulation of organelle organizationGO:00106381280.012
benzene containing compound metabolic processGO:004253750.012
response to nitrosative stressGO:005140910.012
regulation of vesicle mediated transportGO:00606271390.012
cellular response to cytokine stimulusGO:00713451890.012
purine nucleotide catabolic processGO:00061952110.012
alpha amino acid catabolic processGO:1901606180.012
lymphocyte mediated immunityGO:00024491390.012
positive regulation of kinase activityGO:00336741550.011
respiratory system developmentGO:00605411900.011
regulation of cell adhesionGO:00301551540.011
vitamin transportGO:0051180100.011
cellular metal ion homeostasisGO:00068751510.011
isoprenoid metabolic processGO:0006720290.011
skeletal system morphogenesisGO:00487052030.011
cellular response to acid chemicalGO:0071229680.011
regulation of ion transmembrane transportGO:00347651190.011
response to corticosteroneGO:005141210.011
regulation of protein maturationGO:1903317960.011
metal ion homeostasisGO:00550651890.011
nephron epithelium developmentGO:0072009920.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
mrna metabolic processGO:0016071840.011
hair follicle developmentGO:0001942850.011
regulation of wnt signaling pathwayGO:00301111230.011
vitamin d3 metabolic processGO:007064030.011
neuromuscular processGO:0050905990.011
negative regulation of protein modification processGO:00314001630.011
regulation of protein processingGO:0070613960.011
extracellular structure organizationGO:00430621480.011
positive regulation of cell motilityGO:20001471160.011
circadian rhythmGO:00076231140.011
ribonucleotide catabolic processGO:00092612080.011
endocytosisGO:00068971680.011
protein oligomerizationGO:0051259670.011
regulation of fatty acid metabolic processGO:0019217280.011
norepinephrine transportGO:001587420.011
neuron migrationGO:00017641220.011
covalent chromatin modificationGO:00165691630.011
diacylglycerol biosynthetic processGO:000665120.011
retinoid metabolic processGO:0001523240.011
hexose transportGO:0008645560.011
regulation of vacuole organizationGO:004408840.011
regulation of bindingGO:00510981110.011
angiogenesisGO:00015252010.011
regulation of t cell activationGO:00508631700.011
glutamine family amino acid biosynthetic processGO:000908420.011
retrograde transport endosome to golgiGO:004214720.011
positive regulation of cell projection organizationGO:0031346950.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
regulation of t cell proliferationGO:0042129920.011
skeletal muscle organ developmentGO:00605381630.011
generation of precursor metabolites and energyGO:00060911030.011
amino acid transportGO:0006865610.011
long chain fatty acid importGO:004453920.011
regulation of phosphatidylcholine biosynthetic processGO:200124520.011
spermatid differentiationGO:00485151150.011
negative regulation of protein phosphorylationGO:00019331260.011
response to steroid hormoneGO:0048545560.011
positive regulation of cellular ph reductionGO:003284920.011
cytokine mediated signaling pathwayGO:00192211150.011
cellular response to nutrient levelsGO:0031669640.011
neuron deathGO:00709971540.011
regulation of organ morphogenesisGO:20000271440.010
myeloid leukocyte differentiationGO:00025731190.010
cellular protein complex assemblyGO:00436231160.010
Worm
sodium ion transportGO:0006814730.010
gtp metabolic processGO:00460391440.010
plasma membrane organizationGO:0007009900.010
androgen biosynthetic processGO:000670240.010
development of primary female sexual characteristicsGO:0046545730.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
porphyrin containing compound metabolic processGO:0006778220.010
regulation of purine nucleotide catabolic processGO:00331211220.010
positive regulation of fatty acid oxidationGO:004632140.010
histone modificationGO:00165701590.010
retinoic acid metabolic processGO:0042573120.010
ketone catabolic processGO:004218230.010
response to growth factorGO:00708481980.010
cell maturationGO:00484691270.010
mitochondrion organizationGO:00070051340.010
regulation of cell migrationGO:00303342190.010
calcium ion transportGO:00068161590.010
positive regulation of nucleotide metabolic processGO:00459811140.010
embryonic appendage morphogenesisGO:00351131260.010
regulation of map kinase activityGO:00434051200.010
water soluble vitamin biosynthetic processGO:004236430.010
extracellular matrix organizationGO:00301981470.010
reactive nitrogen species metabolic processGO:200105700.010
lateral inhibitionGO:004633110.010

Pcbd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.064
disease of cellular proliferationDOID:1456600.030
inherited metabolic disorderDOID:65500.028
cancerDOID:16200.027
organ system cancerDOID:005068600.025
nervous system diseaseDOID:86300.020
disease of anatomical entityDOID:700.020
cardiovascular system diseaseDOID:128700.019
kidney cancerDOID:26300.016
renal carcinomaDOID:445100.016
urinary system cancerDOID:399600.016
renal cell carcinomaDOID:445000.016
immune system diseaseDOID:291400.016
musculoskeletal system diseaseDOID:1700.014
acquired metabolic diseaseDOID:006015800.014
hematopoietic system diseaseDOID:7400.013
connective tissue diseaseDOID:6500.012
thoracic cancerDOID:509300.012
bone diseaseDOID:008000100.011