Mus musculus

7 known processes

Klk1b21

kallikrein 1-related peptidase b21

(Aliases: mGk-21,Klk21)

Klk1b21 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
kinin cascadeGO:000225420.986
Mouse
tissue kallikrein kinin cascadeGO:000225510.986
Mouse
bradykinin biosynthetic processGO:000293610.980
Mouse
left ventricular cardiac muscle tissue morphogenesisGO:000322020.966
Mouse
cell cell recognitionGO:0009988440.940
Mouse
positive regulation of lipid kinase activityGO:0090218110.908
Mouse
neuronal action potentialGO:0019228540.907
binding of sperm to zona pellucidaGO:0007339340.892
Mouse
protein activation cascadeGO:0072376190.890
Mouse
vasodilationGO:0042311280.887
Mouse
ensheathment of neuronsGO:0007272760.871
Mouse
positive regulation of vasoconstrictionGO:004590740.867
Rat
action potentialGO:0001508780.865
cellular lipid metabolic processGO:00442553230.851
Mouse
negative regulation of neuron projection regenerationGO:007057130.833
Mouse
vascular process in circulatory systemGO:0003018620.794
Mouse Rat
regulation of blood pressureGO:0008217930.791
Mouse
myelinationGO:0042552740.771
Mouse
heart contractionGO:0060047930.745
Mouse
muscle contractionGO:00069361010.742
Mouse
regulation of neuron projection regenerationGO:007057070.741
Mouse
fertilizationGO:00095661270.715
Mouse
regulation of blood vessel sizeGO:0050880560.709
Mouse Rat
positive regulation of transferase activityGO:00513471670.671
Mouse
regulation of response to woundingGO:19030341890.668
Mouse
axon ensheathmentGO:0008366760.656
Mouse
muscle tissue developmentGO:00605373080.643
Mouse
striated muscle contractionGO:0006941450.640
Mouse
sperm egg recognitionGO:0035036370.638
Mouse
keratinocyte proliferationGO:0043616210.634
Mouse
regulation of myelinationGO:0031641200.631
Mouse
regulation of transferase activityGO:00513382630.630
Mouse
multicellular organismal signalingGO:0035637910.593
striated muscle tissue developmentGO:00147062930.593
Mouse
protein processingGO:00164851630.580
Mouse
peptide metabolic processGO:0006518460.570
Mouse
brain renin angiotensin systemGO:000203550.559
Mouse
acute inflammatory responseGO:0002526410.557
Mouse
zymogen activationGO:0031638410.553
Mouse
regulation of blood volume by renin angiotensinGO:000201670.528
Mouse
phospholipid metabolic processGO:0006644870.523
Mouse
regulation of kinase activityGO:00435492490.518
Mouse
vasoconstrictionGO:0042310270.517
Rat
inflammatory responseGO:00069542440.510
Mouse
regulation of systemic arterial blood pressure by renin angiotensinGO:0003081200.496
Mouse
cardiac chamber morphogenesisGO:0003206930.492
Mouse
positive regulation of lipid metabolic processGO:0045834400.488
Mouse
transmission of nerve impulseGO:0019226760.461
positive regulation of phosphatidylinositol 3 kinase activityGO:0043552110.459
Mouse
blood circulationGO:00080151950.451
Mouse Rat
neurological system process involved in regulation of systemic arterial blood pressureGO:0001976180.441
Mouse
regulation of systemic arterial blood pressure by hormoneGO:0001990250.432
Mouse
regulation of phosphatidylinositol 3 kinase activityGO:0043551140.424
Mouse
positive regulation of kinase activityGO:00336741550.413
Mouse
cardiac muscle contractionGO:0060048320.410
Mouse
regulation of tube sizeGO:0035150570.404
Mouse Rat
regulation of anatomical structure sizeGO:00900661780.402
Mouse Rat
cellular amide metabolic processGO:0043603580.395
Mouse
cardiac left ventricle morphogenesisGO:000321490.390
Mouse
epithelial cell proliferationGO:00506731740.375
Mouse
regulation of membrane potentialGO:00423911920.368
regulation of system processGO:00440572000.363
Mouse Rat
regulation of vasoconstrictionGO:0019229140.360
Rat
small gtpase mediated signal transductionGO:0007264970.344
Mouse
synapse organizationGO:00508081250.321
Mouse
protein maturationGO:00516041760.318
Mouse
regulation of lipid kinase activityGO:0043550140.309
Mouse
organonitrogen compound biosynthetic processGO:19015661920.301
Mouse
cardiac chamber developmentGO:00032051080.300
Mouse
muscle system processGO:00030121410.258
Mouse
cardiac ventricle morphogenesisGO:0003208500.256
Mouse
peptide biosynthetic processGO:0043043110.252
Mouse
regulation of blood circulationGO:1903522930.242
Rat
ventricular cardiac muscle tissue morphogenesisGO:0055010320.235
Mouse
odontogenesis of dentin containing toothGO:0042475660.232
heart morphogenesisGO:00030071780.231
Mouse
macromolecule catabolic processGO:00090572810.228
muscle tissue morphogenesisGO:0060415530.226
Mouse
odontogenesisGO:0042476780.218
regulation of systemic arterial blood pressureGO:0003073610.218
Mouse
endocrine processGO:0050886390.190
Mouse
single fertilizationGO:0007338820.187
Mouse
regulation of neurological system processGO:0031644220.184
Mouse
oxidation reduction processGO:00551143420.184
cardiac muscle tissue developmentGO:00487381300.183
Mouse
circulatory system processGO:00030131970.182
Mouse Rat
extracellular structure organizationGO:00430621480.182
positive regulation of blood circulationGO:1903524220.182
Rat
protein catabolic processGO:00301632210.178
cardiac muscle tissue morphogenesisGO:0055008440.175
Mouse
ventricular cardiac muscle tissue developmentGO:0003229380.170
Mouse
extracellular matrix organizationGO:00301981470.170
regulation of ion transportGO:00432692150.153
regulation of cellular response to stressGO:00801351590.151
Mouse
regulation of cell projection organizationGO:00313442060.146
Mouse
amine metabolic processGO:0009308450.142
negative regulation of response to woundingGO:1903035770.140
Mouse
regulation of lipid metabolic processGO:00192161180.120
Mouse
muscle cell developmentGO:00550011330.119
neuron projection regenerationGO:0031102140.115
Mouse
purine containing compound metabolic processGO:00725213110.105
cellular amino acid metabolic processGO:00065201030.104
regulation of neuron differentiationGO:00456642810.103
Mouse
learning or memoryGO:00076111480.098
Mouse
negative regulation of cell projection organizationGO:0031345560.098
Mouse
metal ion homeostasisGO:00550651890.096
carbohydrate biosynthetic processGO:0016051740.088
cation transportGO:00068123990.086
regenerationGO:0031099380.083
Mouse
regulation of cellular amino acid metabolic processGO:000652150.082
cellular ketone metabolic processGO:0042180840.079
positive regulation of protein phosphorylationGO:00019342420.079
mitochondrion organizationGO:00070051340.076
cell recognitionGO:0008037830.074
Mouse
muscle fiber developmentGO:0048747760.074
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044330.074
Mouse
transmembrane transportGO:00550854120.074
cellular response to lipidGO:00713961450.073
unsaturated fatty acid metabolic processGO:0033559310.071
divalent metal ion transportGO:00708381720.070
sensory perceptionGO:00076002450.070
negative regulation of cellular component organizationGO:00511291940.068
Mouse
negative regulation of neurological system processGO:003164570.067
Mouse
amide biosynthetic processGO:0043604160.065
Mouse
blood vessel morphogenesisGO:00485142850.065
germ cell developmentGO:00072811850.064
cardiac ventricle developmentGO:0003231830.063
Mouse
monocarboxylic acid metabolic processGO:00327871910.063
regulation of homeostatic processGO:00328441820.061
positive regulation of programmed cell deathGO:00430682180.060
wound healingGO:00420601570.059
regulation of calcium ion transportGO:0051924690.058
leukocyte differentiationGO:00025213420.057
positive regulation of apoptotic processGO:00430652170.057
muscle cell differentiationGO:00426922610.057
regulation of transmembrane transportGO:00347621280.055
apoptotic signaling pathwayGO:00971903060.055
anatomical structure homeostasisGO:00602491450.052
cellular response to organonitrogen compoundGO:00714171450.052
positive regulation of cell deathGO:00109422240.051
amelogenesisGO:0097186120.051
divalent inorganic cation homeostasisGO:00725071380.051
regulation of metal ion transportGO:00109591060.051
regulation of neuron projection developmentGO:00109751690.048
Mouse
negative regulation of nervous system developmentGO:00519611560.048
Mouse
axon regenerationGO:0031103120.048
Mouse
multicellular organismal homeostasisGO:00488711640.047
hexose metabolic processGO:0019318980.046
striated muscle cell developmentGO:00550021250.046
calcium ion homeostasisGO:00550741270.045
energy derivation by oxidation of organic compoundsGO:0015980770.045
divalent inorganic cation transportGO:00725111780.045
regulation of body fluid levelsGO:00508781620.045
response to insulinGO:00328681000.045
regulation of cell activationGO:00508652890.044
regulation of epithelial cell proliferationGO:00506781410.043
heart processGO:0003015940.043
Mouse
cell chemotaxisGO:0060326810.043
cell divisionGO:00513011200.043
regulation of leukocyte differentiationGO:19021051590.043
nucleobase containing small molecule metabolic processGO:00550863520.042
cation homeostasisGO:00550802120.041
negative regulation of myelinationGO:003164260.041
Mouse
skin developmentGO:00435882200.041
regulation of ion transmembrane transportGO:00347651190.041
positive regulation of thymocyte migrationGO:200041220.041
skeletal muscle organ developmentGO:00605381630.039
calcium ion transportGO:00068161590.038
spermatogenesisGO:00072832840.038
negative regulation of cell proliferationGO:00082852960.038
negative regulation of neuron differentiationGO:00456651010.038
Mouse
potassium ion homeostasisGO:005507540.037
cognitionGO:00508901490.036
Mouse
negative regulation of protein metabolic processGO:00512482820.036
neurotransmitter secretionGO:0007269620.035
response to organic cyclic compoundGO:00140701980.035
response to organonitrogen compoundGO:00102432460.035
methylationGO:00322591340.035
dna metabolic processGO:00062593030.034
maintenance of locationGO:0051235890.034
inorganic ion transmembrane transportGO:00986602340.033
response to radiationGO:00093141650.033
protein kinase b signalingGO:0043491740.033
cellular response to peptideGO:1901653920.033
glial cell developmentGO:0021782540.033
icosanoid metabolic processGO:0006690330.033
cellular chemical homeostasisGO:00550822150.033
negative regulation of cellular protein metabolic processGO:00322692470.032
regulation of eosinophil migrationGO:200041620.032
tissue homeostasisGO:00018941150.031
nucleotide metabolic processGO:00091173320.031
response to peptide hormoneGO:00434341270.030
cell type specific apoptotic processGO:00972852680.030
coagulationGO:0050817780.030
positive regulation of cellular amino acid metabolic processGO:004576430.029
regulation of cellular amine metabolic processGO:0033238200.029
cellular divalent inorganic cation homeostasisGO:00725031270.029
reactive oxygen species metabolic processGO:0072593840.029
generation of precursor metabolites and energyGO:00060911030.028
carbohydrate metabolic processGO:00059752300.028
regulation of map kinase activityGO:00434051200.027
skeletal system developmentGO:00015013560.027
homeostasis of number of cellsGO:00488722100.026
regulation of cellular ketone metabolic processGO:0010565660.026
peptide hormone secretionGO:00300721090.026
cellular carbohydrate metabolic processGO:00442621190.025
actin cytoskeleton organizationGO:00300362200.025
regulation of tissue remodelingGO:0034103380.025
macromolecule methylationGO:00434141200.025
blood coagulationGO:0007596760.025
purine nucleotide metabolic processGO:00061633020.025
positive regulation of cell motilityGO:20001471160.025
lipid biosynthetic processGO:00086101790.025
progesterone metabolic processGO:004244840.025
fatty acid metabolic processGO:00066311210.025
ribonucleotide metabolic processGO:00092592910.024
positive regulation of protein kinase b signalingGO:0051897320.024
organic cyclic compound catabolic processGO:19013612950.024
organic hydroxy compound metabolic processGO:19016152030.024
nitrogen compound transportGO:00717052710.024
sequestering of metal ionGO:0051238190.024
positive regulation of map kinase activityGO:0043406840.023
monosaccharide metabolic processGO:00059961060.023
cellular response to organic cyclic compoundGO:0071407870.022
cellular response to oxidative stressGO:0034599760.022
organelle fissionGO:00482851700.022
response to light stimulusGO:00094161350.022
cellular ion homeostasisGO:00068731650.022
positive regulation of cytokine productionGO:00018191740.021
cellular metal ion homeostasisGO:00068751510.021
locomotory behaviorGO:00076261950.021
neuron deathGO:00709971540.021
regulation of protein kinase b signalingGO:0051896560.021
cellular homeostasisGO:00197252400.021
negative regulation of cell developmentGO:00107211690.021
Mouse
regulation of secretionGO:00510462740.020
carbohydrate homeostasisGO:00335001280.020
cellular amine metabolic processGO:0044106440.020
purine nucleoside metabolic processGO:00422782410.020
immune effector processGO:00022523210.020
amide transportGO:00428861380.020
angiogenesisGO:00015252010.020
alpha amino acid metabolic processGO:1901605590.020
ribonucleoside metabolic processGO:00091192450.020
calcium mediated signalingGO:0019722460.020
respiratory system developmentGO:00605411900.020
response to oxidative stressGO:00069791230.020
ion transmembrane transportGO:00342203610.020
olfactory learningGO:000835520.020
organophosphate biosynthetic processGO:00904071220.019
inorganic cation transmembrane transportGO:00986622070.019
cellular response to peptide hormone stimulusGO:0071375920.019
myeloid leukocyte migrationGO:0097529570.019
negative regulation of molecular functionGO:00440922580.019
regulation of protein serine threonine kinase activityGO:00719001570.019
cellular response to steroid hormone stimulusGO:0071383330.019
response to acid chemicalGO:00011011110.019
eosinophil migrationGO:007267730.019
fatty acid derivative metabolic processGO:1901568330.019
lymphocyte differentiationGO:00300982420.019
regulation of cellular carbohydrate metabolic processGO:0010675750.019
epidermis developmentGO:00085441870.019
response to testosteroneGO:003357430.019
regulation of organelle organizationGO:00330432890.018
female gamete generationGO:0007292740.018
cellular component assembly involved in morphogenesisGO:00109271390.018
sequestering of calcium ionGO:0051208180.018
single organismal cell cell adhesionGO:00163371310.018
negative regulation of protein modification processGO:00314001630.018
regulation of myeloid leukocyte differentiationGO:0002761580.018
hormone secretionGO:00468791280.018
cellular response to insulin stimulusGO:0032869780.018
thymocyte migrationGO:007267920.018
nucleoside phosphate metabolic processGO:00067533380.018
myotube differentiationGO:00149021050.018
epithelial tube morphogenesisGO:00605623030.018
response to inorganic substanceGO:0010035960.018
regulation of transporter activityGO:0032409570.017
engulfment of apoptotic cellGO:004365230.017
cellular potassium ion transportGO:0071804430.017
negative regulation of epithelial cell proliferationGO:0050680640.017
response to molecule of bacterial originGO:00022371430.017
cellular response to acid chemicalGO:0071229680.017
organonitrogen compound catabolic processGO:19015652640.017
epithelial cell developmentGO:00020641590.017
sperm motilityGO:0030317470.017
carbohydrate derivative catabolic processGO:19011362310.017
gluconeogenesisGO:0006094390.017
regulation of myeloid cell differentiationGO:0045637960.016
insulin receptor signaling pathwayGO:0008286490.016
regulation of gluconeogenesisGO:0006111300.016
monosaccharide biosynthetic processGO:0046364440.016
establishment or maintenance of cell polarityGO:0007163860.016
hexose biosynthetic processGO:0019319390.016
regulation of cell motilityGO:20001452360.016
memoryGO:0007613580.016
Mouse
carbohydrate derivative biosynthetic processGO:19011371830.016
cation transmembrane transportGO:00986552660.016
activation of mapk activityGO:0000187590.016
positive regulation of potassium ion transportGO:004326830.016
response to extracellular stimulusGO:00099911270.016
regulation of protein localizationGO:00328802310.016
aromatic compound catabolic processGO:00194392860.016
cellular response to external stimulusGO:0071496880.016
myeloid cell differentiationGO:00300992330.016
regulation of proteolysisGO:00301621640.016
negative regulation of organelle organizationGO:0010639900.015
peptidyl amino acid modificationGO:00181933360.015
glycerolipid biosynthetic processGO:0045017500.015
negative regulation of neuron projection developmentGO:0010977500.015
Mouse
positive regulation of ion transmembrane transportGO:0034767240.015
positive regulation of cellular amine metabolic processGO:003324050.015
b cell activationGO:00421131610.015
cellular response to hormone stimulusGO:00328701500.015
mapk cascadeGO:00001652810.015
positive regulation of glucose metabolic processGO:0010907210.015
response to lipopolysaccharideGO:00324961280.015
regulation of carbohydrate biosynthetic processGO:0043255400.015
male gamete generationGO:00482322850.015
t cell differentiationGO:00302171740.015
purine ribonucleotide metabolic processGO:00091502900.015
cellular response to extracellular stimulusGO:0031668810.014
positive regulation of homeostatic processGO:0032846640.014
energy reserve metabolic processGO:0006112390.014
regulation of ion homeostasisGO:2000021640.014
adherens junction maintenanceGO:003433410.014
nucleoside metabolic processGO:00091162460.014
sulfur compound metabolic processGO:00067901000.014
ribose phosphate metabolic processGO:00196932910.014
positive regulation of cell activationGO:00508671580.014
negative regulation of phagocytosisGO:005076540.014
cell maturationGO:00484691270.013
regulation of wound healingGO:0061041400.013
digestive system developmentGO:00551232000.013
positive regulation of ion transportGO:0043270650.013
dna modificationGO:0006304500.013
dephosphorylationGO:00163111290.013
response to peptideGO:19016521360.013
negative regulation of homeostatic processGO:0032845710.013
response to nutrient levelsGO:00316671090.013
mitotic cell cycle processGO:19030471590.013
covalent chromatin modificationGO:00165691630.013
positive regulation of eosinophil migrationGO:200041820.013
response to superoxideGO:0000303160.013
glucose homeostasisGO:00425931280.013
regulation of vesicle mediated transportGO:00606271390.013
rhythmic processGO:00485111740.013
positive regulation of carbohydrate metabolic processGO:0045913300.013
cellular response to lipopolysaccharideGO:0071222770.012
monovalent inorganic cation homeostasisGO:0055067330.012
small molecule biosynthetic processGO:00442831320.012
nucleoside phosphate catabolic processGO:19012922220.012
regulation of potassium ion transmembrane transportGO:1901379110.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
urogenital system developmentGO:00016552610.012
regulation of hormone levelsGO:00108172110.012
positive regulation of protein kinase activityGO:00458601440.012
purine nucleoside catabolic processGO:00061522050.012
adult locomotory behaviorGO:0008344910.012
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.012
negative regulation of phosphorus metabolic processGO:00105631840.012
positive regulation of mapk cascadeGO:00434101700.012
nucleoside catabolic processGO:00091642060.012
purine nucleotide catabolic processGO:00061952110.012
nucleotide catabolic processGO:00091662170.012
posttranscriptional regulation of gene expressionGO:00106081550.012
calcium ion transport into cytosolGO:0060402480.012
cell activation involved in immune responseGO:00022631260.012
leukocyte migrationGO:00509001240.012
glycogen metabolic processGO:0005977320.012
regulation of nucleotide metabolic processGO:00061401690.012
extrinsic apoptotic signaling pathwayGO:00971911260.011
production of molecular mediator of immune responseGO:00024401030.011
renal system developmentGO:00720012250.011
inorganic anion transportGO:0015698430.011
glucose metabolic processGO:0006006920.011
mitotic cytokinesisGO:000028140.011
regulation of mapk cascadeGO:00434082480.011
schwann cell differentiationGO:0014037260.011
extracellular matrix dependent thymocyte migrationGO:007268010.011
b cell differentiationGO:0030183780.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
organelle assemblyGO:00709251770.011
glycoprotein biosynthetic processGO:0009101890.011
regulation of carbohydrate metabolic processGO:0006109750.011
regulation of purine nucleotide metabolic processGO:19005421690.011
leukocyte activation involved in immune responseGO:00023661260.011
leukocyte proliferationGO:00706611720.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
positive regulation of cellular carbohydrate metabolic processGO:0010676290.011
positive regulation of membrane protein ectodomain proteolysisGO:005104430.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
positive regulation of fibronectin dependent thymocyte migrationGO:200041510.011
positive regulation of cellular catabolic processGO:00313311480.011
peptidyl serine modificationGO:0018209830.011
regulation of membrane protein ectodomain proteolysisGO:005104330.011
regulation of antigen receptor mediated signaling pathwayGO:0050854290.011
circadian rhythmGO:00076231140.011
negative regulation of intracellular signal transductionGO:19025321670.011
meiotic nuclear divisionGO:00071261150.011
regulation of chromatin organizationGO:1902275570.010
cellular response to dna damage stimulusGO:00069742070.010
g protein coupled receptor signaling pathwayGO:00071862430.010
regulation of complement activation classical pathwayGO:003045010.010
digestive tract morphogenesisGO:00485461470.010
apoptotic mitochondrial changesGO:0008637480.010
nuclear divisionGO:00002801580.010
regulation of cellular catabolic processGO:00313292420.010
glycosyl compound catabolic processGO:19016582060.010
hemostasisGO:0007599780.010
gonad developmentGO:00084061410.010
peptide secretionGO:00027901140.010
fat cell differentiationGO:00454441600.010
potassium ion transmembrane transportGO:0071805430.010
purine containing compound catabolic processGO:00725232130.010
spermatid differentiationGO:00485151150.010
cellular calcium ion homeostasisGO:00068741190.010
positive regulation of intracellular transportGO:0032388700.010
organic acid biosynthetic processGO:0016053860.010

Klk1b21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.033
disease of anatomical entityDOID:700.033
central nervous system diseaseDOID:33100.019
disease of cellular proliferationDOID:1456600.015
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.013
organ system cancerDOID:005068600.012
cancerDOID:16200.012
neurodegenerative diseaseDOID:128900.010
hematologic cancerDOID:253100.010
immune system cancerDOID:006008300.010