Mus musculus

11 known processes

Klk1b22

kallikrein 1-related peptidase b22

(Aliases: MGC118112,Egfbp-1,Klk22,mGk-22,Egfbp1)

Klk1b22 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
inflammatory responseGO:00069542440.088
Mouse
positive regulation of vasoconstrictionGO:004590740.086
Rat
regulation of transferase activityGO:00513382630.079
Mouse
striated muscle tissue developmentGO:00147062930.075
Mouse
cellular amino acid metabolic processGO:00065201030.075
oxidation reduction processGO:00551143420.074
regulation of kinase activityGO:00435492490.064
Mouse
cellular lipid metabolic processGO:00442553230.062
Mouse
amine metabolic processGO:0009308450.059
protein maturationGO:00516041760.059
positive regulation of kinase activityGO:00336741550.056
Mouse
fertilizationGO:00095661270.055
Mouse
regulation of cellular amine metabolic processGO:0033238200.053
action potentialGO:0001508780.053
small gtpase mediated signal transductionGO:0007264970.052
Mouse
muscle system processGO:00030121410.051
Mouse
regulation of response to woundingGO:19030341890.050
Mouse
positive regulation of cellular amine metabolic processGO:003324050.050
protein activation cascadeGO:0072376190.049
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.049
response to organic cyclic compoundGO:00140701980.048
protein processingGO:00164851630.048
regulation of cellular ketone metabolic processGO:0010565660.048
cellular amine metabolic processGO:0044106440.048
epithelial cell proliferationGO:00506731740.047
Mouse
male gamete generationGO:00482322850.044
regulation of cytokine productionGO:00018172660.044
macromolecule catabolic processGO:00090572810.043
Mouse
protein catabolic processGO:00301632210.043
Mouse
cellular ketone metabolic processGO:0042180840.042
heart contractionGO:0060047930.042
Mouse
cytokine productionGO:00018163190.042
regulation of neuron projection developmentGO:00109751690.042
Mouse
negative regulation of protein metabolic processGO:00512482820.041
regulation of cell projection organizationGO:00313442060.041
Mouse
negative regulation of neuron projection regenerationGO:007057130.040
Mouse
positive regulation of transferase activityGO:00513471670.039
Mouse
extracellular structure organizationGO:00430621480.037
Mouse
regulation of lipid metabolic processGO:00192161180.037
Mouse
negative regulation of cell developmentGO:00107211690.036
Mouse
blood vessel morphogenesisGO:00485142850.033
cell adhesionGO:00071553290.033
cognitionGO:00508901490.033
Mouse
spermatogenesisGO:00072832840.033
synapse organizationGO:00508081250.032
Mouse
response to organonitrogen compoundGO:00102432460.032
learning or memoryGO:00076111480.032
Mouse
binding of sperm to zona pellucidaGO:0007339340.031
Mouse
cation transportGO:00068123990.031
striated muscle contractionGO:0006941450.031
Mouse
lipid biosynthetic processGO:00086101790.031
cellular chemical homeostasisGO:00550822150.031
maintenance of locationGO:0051235890.030
regulation of anatomical structure sizeGO:00900661780.030
Mouse Rat
cardiac muscle contractionGO:0060048320.030
Mouse
neuronal action potentialGO:0019228540.030
regulation of cellular amino acid metabolic processGO:000652150.030
regulation of neuron differentiationGO:00456642810.030
Mouse
muscle tissue developmentGO:00605373080.029
Mouse
ion transmembrane transportGO:00342203610.029
multicellular organismal signalingGO:0035637910.029
cell type specific apoptotic processGO:00972852680.028
purine ribonucleotide metabolic processGO:00091502900.028
transmembrane transportGO:00550854120.028
organonitrogen compound biosynthetic processGO:19015661920.028
Mouse
regulation of blood pressureGO:0008217930.028
Mouse
cellular homeostasisGO:00197252400.027
regulation of system processGO:00440572000.026
Mouse Rat
positive regulation of lipid metabolic processGO:0045834400.026
Mouse
regulation of epithelial cell proliferationGO:00506781410.026
regulation of systemic arterial blood pressureGO:0003073610.026
Mouse
regulation of cellular response to stressGO:00801351590.026
Mouse
regulation of membrane potentialGO:00423911920.026
peptidyl amino acid modificationGO:00181933360.026
cell cell recognitionGO:0009988440.025
Mouse
regulation of protein serine threonine kinase activityGO:00719001570.025
synaptic transmissionGO:00072683290.025
Mouse
blood circulationGO:00080151950.025
Mouse Rat
negative regulation of molecular functionGO:00440922580.025
gland developmentGO:00487323300.025
regulation of cell activationGO:00508652890.025
mapk cascadeGO:00001652810.024
transmission of nerve impulseGO:0019226760.024
vasodilationGO:0042311280.024
Mouse
regulation of homeostatic processGO:00328441820.024
negative regulation of response to woundingGO:1903035770.024
Mouse
cellular response to organonitrogen compoundGO:00714171450.024
germ cell developmentGO:00072811850.024
nucleobase containing small molecule metabolic processGO:00550863520.024
negative regulation of cellular component organizationGO:00511291940.024
Mouse
muscle contractionGO:00069361010.023
Mouse
positive regulation of lipid kinase activityGO:0090218110.023
Mouse
purine containing compound metabolic processGO:00725213110.023
positive regulation of cytokine productionGO:00018191740.023
cation homeostasisGO:00550802120.022
organic cyclic compound catabolic processGO:19013612950.022
positive regulation of cell deathGO:00109422240.022
monocarboxylic acid metabolic processGO:00327871910.022
t cell activationGO:00421102890.022
regulation of protein localizationGO:00328802310.022
cellular response to lipidGO:00713961450.022
calcium ion homeostasisGO:00550741270.021
nucleoside phosphate metabolic processGO:00067533380.021
immune effector processGO:00022523210.021
positive regulation of protein modification processGO:00314012990.021
zymogen activationGO:0031638410.021
heart morphogenesisGO:00030071780.021
Mouse
regulation of defense responseGO:00313472330.021
circulatory system processGO:00030131970.020
Mouse Rat
regulation of organelle organizationGO:00330432890.020
peptide metabolic processGO:0006518460.020
Mouse
response to peptideGO:19016521360.020
positive regulation of secretionGO:00510471300.020
spermatid developmentGO:00072861080.020
aromatic compound catabolic processGO:00194392860.020
single fertilizationGO:0007338820.020
Mouse
positive regulation of programmed cell deathGO:00430682180.020
cellular amide metabolic processGO:0043603580.020
Mouse
fatty acid metabolic processGO:00066311210.020
reactive nitrogen species metabolic processGO:200105700.020
glycoprotein metabolic processGO:00091001160.020
sulfur compound metabolic processGO:00067901000.020
cardiac muscle tissue developmentGO:00487381300.020
Mouse
innate immune responseGO:00450871570.020
memoryGO:0007613580.020
Mouse
positive regulation of apoptotic processGO:00430652170.020
regulation of blood vessel sizeGO:0050880560.020
Mouse Rat
response to molecule of bacterial originGO:00022371430.019
response to inorganic substanceGO:0010035960.019
cellular ion homeostasisGO:00068731650.019
metal ion homeostasisGO:00550651890.019
kinin cascadeGO:000225420.019
Mouse
reactive oxygen species metabolic processGO:0072593840.019
fat cell differentiationGO:00454441600.019
microtubule based processGO:00070172360.019
homeostasis of number of cellsGO:00488722100.019
skeletal muscle organ developmentGO:00605381630.018
positive regulation of protein kinase activityGO:00458601440.018
regulation of secretionGO:00510462740.018
hematopoietic progenitor cell differentiationGO:00022441430.018
negative regulation of cellular protein metabolic processGO:00322692470.018
negative regulation of immune system processGO:00026832090.018
regulation of mapk cascadeGO:00434082480.018
negative regulation of cellular amine metabolic processGO:003323910.018
regulation of lymphocyte activationGO:00512492400.018
cellular response to hormone stimulusGO:00328701500.018
reactive oxygen species biosynthetic processGO:190340980.018
carbohydrate derivative biosynthetic processGO:19011371830.018
cellular metal ion homeostasisGO:00068751510.018
myeloid cell differentiationGO:00300992330.018
sequestering of metal ionGO:0051238190.018
cellular response to biotic stimulusGO:0071216920.018
negative regulation of phosphorus metabolic processGO:00105631840.018
regulation of feeding behaviorGO:006025930.018
heart processGO:0003015940.018
Mouse
positive regulation of protein phosphorylationGO:00019342420.017
chromatin disassemblyGO:003149810.017
sperm egg recognitionGO:0035036370.017
Mouse
apoptotic signaling pathwayGO:00971903060.017
lymphocyte proliferationGO:00466511640.017
response to insulinGO:00328681000.017
regulation of secretion by cellGO:19035302490.017
glycosyl compound metabolic processGO:19016572460.017
cofactor metabolic processGO:0051186800.017
rhythmic processGO:00485111740.017
spermatid differentiationGO:00485151150.017
carbohydrate biosynthetic processGO:0016051740.017
cardiac chamber developmentGO:00032051080.017
Mouse
ribose phosphate metabolic processGO:00196932910.017
muscle cell differentiationGO:00426922610.017
leukocyte differentiationGO:00025213420.017
activation of immune responseGO:00022531380.017
carbohydrate derivative catabolic processGO:19011362310.017
cellular response to organic cyclic compoundGO:0071407870.017
response to acid chemicalGO:00011011110.017
protein secretionGO:00093061110.017
positive regulation of protein serine threonine kinase activityGO:00719021060.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
myosin filament organizationGO:003103330.016
chromatin organizationGO:00063252060.016
extracellular matrix organizationGO:00301981470.016
Mouse
regulation of cell cycle processGO:00105641600.016
negative regulation of phosphorylationGO:00423261660.016
negative regulation of nervous system developmentGO:00519611560.016
Mouse
regulation of reactive oxygen species metabolic processGO:2000377400.016
nucleotide metabolic processGO:00091173320.016
regulation of hormone levelsGO:00108172110.016
dephosphorylationGO:00163111290.016
defense response to other organismGO:00985421970.016
posttranscriptional regulation of gene expressionGO:00106081550.016
locomotory behaviorGO:00076261950.016
small molecule biosynthetic processGO:00442831320.016
sensory perceptionGO:00076002450.016
cardiac chamber morphogenesisGO:0003206930.016
Mouse
regulation of protein processingGO:0070613960.016
regulation of cell cycleGO:00517262810.016
regenerationGO:0031099380.016
Mouse
single organism cell adhesionGO:00986021560.015
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044330.015
Mouse
regulation of tube sizeGO:0035150570.015
Mouse Rat
cellular response to lipopolysaccharideGO:0071222770.015
negative regulation of cell proliferationGO:00082852960.015
response to extracellular stimulusGO:00099911270.015
negative regulation of protein modification processGO:00314001630.015
cellular nitrogen compound catabolic processGO:00442702800.015
vascular process in circulatory systemGO:0003018620.015
Mouse Rat
protein glycosylationGO:0006486550.015
regulation of protein maturationGO:1903317960.015
response to radiationGO:00093141650.015
negative regulation of cellular amino acid metabolic processGO:004576300.015
ras protein signal transductionGO:0007265770.015
glycoprotein biosynthetic processGO:0009101890.015
sequestering of calcium ionGO:0051208180.015
regulation of phosphatidylinositol 3 kinase activityGO:0043551140.015
Mouse
cellular response to molecule of bacterial originGO:0071219830.015
forebrain developmentGO:00309003020.015
nucleoside metabolic processGO:00091162460.015
g protein coupled receptor signaling pathwayGO:00071862430.015
cellular response to dna damage stimulusGO:00069742070.015
ribonucleoside metabolic processGO:00091192450.015
purine ribonucleoside metabolic processGO:00461282410.015
wnt signaling pathwayGO:00160551880.015
phospholipid metabolic processGO:0006644870.015
Mouse
regulation of establishment of protein localizationGO:00702011810.015
response to lipopolysaccharideGO:00324961280.015
dna metabolic processGO:00062593030.014
ribonucleotide metabolic processGO:00092592910.014
response to testosteroneGO:003357430.014
regulation of leukocyte differentiationGO:19021051590.014
multicellular organismal homeostasisGO:00488711640.014
ossificationGO:00015032160.014
heterocycle catabolic processGO:00467002800.014
organonitrogen compound catabolic processGO:19015652640.014
positive regulation of cell projection organizationGO:0031346950.014
cellular response to growth factor stimulusGO:00713631970.014
regulation of proteolysisGO:00301621640.014
epithelial tube morphogenesisGO:00605623030.014
multicellular organism growthGO:00352641610.014
peptidyl tyrosine phosphorylationGO:00181081430.014
lymphocyte mediated immunityGO:00024491390.014
regulation of cell adhesionGO:00301551540.014
regulation of hydrolase activityGO:00513362460.014
placenta developmentGO:00018901400.014
negative regulation of protein phosphorylationGO:00019331260.014
ribonucleoside triphosphate metabolic processGO:00091992200.014
cytokine mediated signaling pathwayGO:00192211150.014
carbohydrate metabolic processGO:00059752300.014
regulation of lymphocyte mediated immunityGO:0002706840.014
negative regulation of phosphate metabolic processGO:00459361840.014
regulation of inflammatory responseGO:00507271470.014
nucleoside phosphate catabolic processGO:19012922220.014
cellular carbohydrate metabolic processGO:00442621190.014
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.014
single organismal cell cell adhesionGO:00163371310.014
divalent inorganic cation homeostasisGO:00725071380.013
response to oxidative stressGO:00069791230.013
cytoplasmic transportGO:00164822340.013
cellular response to cytokine stimulusGO:00713451890.013
camera type eye developmentGO:00430102660.013
cellular calcium ion homeostasisGO:00068741190.013
response to growth factorGO:00708481980.013
acute inflammatory responseGO:0002526410.013
Mouse
regulation of ion transmembrane transportGO:00347651190.013
mitochondrion organizationGO:00070051340.013
glycosylationGO:0070085620.013
purine nucleoside metabolic processGO:00422782410.013
respiratory system developmentGO:00605411900.013
regulation of protein transportGO:00512231630.013
regulation of t cell activationGO:00508631700.013
response to peptide hormoneGO:00434341270.013
sensory organ morphogenesisGO:00905962420.013
compound eye developmentGO:004874910.013
regulation of reactive oxygen species biosynthetic processGO:190342620.013
immune response regulating signaling pathwayGO:00027641250.013
steroid biosynthetic processGO:0006694470.013
cellular response to peptideGO:1901653920.013
regulation of endopeptidase activityGO:0052548890.013
regulation of ion transportGO:00432692150.013
cellular response to peptide hormone stimulusGO:0071375920.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
macromolecule glycosylationGO:0043413550.013
nucleoside catabolic processGO:00091642060.013
organelle localizationGO:00516401790.013
regulation of systemic arterial blood pressure by hormoneGO:0001990250.013
Mouse
response to light stimulusGO:00094161350.013
regulation of fat cell differentiationGO:0045598810.013
nucleotide catabolic processGO:00091662170.013
protein modification by small protein conjugation or removalGO:00706472070.012
left ventricular cardiac muscle tissue morphogenesisGO:000322020.012
Mouse
lipid localizationGO:00108761260.012
secondary alcohol metabolic processGO:190265230.012
digestive tract developmentGO:00485651900.012
ensheathment of neuronsGO:0007272760.012
Mouse
t cell proliferationGO:00420981200.012
vasoconstrictionGO:0042310270.012
Rat
endocytosisGO:00068971680.012
nucleoside triphosphate catabolic processGO:00091432050.012
cation transmembrane transportGO:00986552660.012
nitrogen compound transportGO:00717052710.012
anion transportGO:00068201770.012
negative regulation of insulin secretion involved in cellular response to glucose stimulusGO:006117940.012
morphogenesis of a branching structureGO:00017632030.012
cellular alcohol metabolic processGO:004410730.012
defense response to bacteriumGO:00427421190.012
nucleoside triphosphate metabolic processGO:00091412300.012
sperm motilityGO:0030317470.012
cellular macromolecule catabolic processGO:00442652060.012
embryonic organ morphogenesisGO:00485622760.012
male sex differentiationGO:00466611090.012
cellular response to cadmium ionGO:007127630.012
negative regulation of neuron projection developmentGO:0010977500.012
Mouse
protein localization to organelleGO:00333651850.012
response to nutrient levelsGO:00316671090.012
organic anion transportGO:00157111370.012
membrane organizationGO:00610242450.012
neurological system process involved in regulation of systemic arterial blood pressureGO:0001976180.012
Mouse
chromatin modificationGO:00165681870.012
peptidyl tyrosine modificationGO:00182121450.012
regulation of neurological system processGO:0031644220.012
Mouse
negative regulation of protein maturationGO:1903318790.012
membrane lipid metabolic processGO:0006643530.012
regulation of systemic arterial blood pressure by renin angiotensinGO:0003081200.012
Mouse
angiogenesisGO:00015252010.012
leukocyte proliferationGO:00706611720.012
regulation of protein kinase activityGO:00458592320.011
organic hydroxy compound metabolic processGO:19016152030.011
generation of precursor metabolites and energyGO:00060911030.011
myeloid leukocyte differentiationGO:00025731190.011
negative regulation of intracellular signal transductionGO:19025321670.011
ear developmentGO:00435832000.011
carbohydrate homeostasisGO:00335001280.011
purine nucleoside triphosphate metabolic processGO:00091442260.011
regulation of leukocyte proliferationGO:00706631210.011
positive regulation of mapk cascadeGO:00434101700.011
icosanoid metabolic processGO:0006690330.011
steroid metabolic processGO:00082021190.011
cytosolic calcium ion homeostasisGO:0051480700.011
regulation of map kinase activityGO:00434051200.011
purine nucleotide catabolic processGO:00061952110.011
regulation of myelinationGO:0031641200.011
Mouse
leukocyte mediated immunityGO:00024431740.011
protein modification by small protein conjugationGO:00324461870.011
methylationGO:00322591340.011
regulation of cellular carbohydrate metabolic processGO:0010675750.011
response to amino acidGO:0043200370.011
ameboidal type cell migrationGO:00016671280.011
purine ribonucleotide catabolic processGO:00091542080.011
regulation of blood circulationGO:1903522930.011
Rat
positive regulation of hydrolase activityGO:00513451480.011
positive regulation of insulin receptor signaling pathwayGO:004662840.011
alpha amino acid metabolic processGO:1901605590.011
cellular response to acid chemicalGO:0071229680.011
energy derivation by oxidation of organic compoundsGO:0015980770.011
olfactory learningGO:000835520.011
organelle fissionGO:00482851700.011
positive regulation of leukocyte differentiationGO:1902107860.011
developmental maturationGO:00217001930.011
hexose metabolic processGO:0019318980.011
digestive system developmentGO:00551232000.011
regulation of cellular component biogenesisGO:00440871810.011
mitotic cell cycle processGO:19030471590.011
positive regulation of defense responseGO:00313491240.011
regulation of action potentialGO:009890040.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
positive regulation of blood circulationGO:1903524220.011
Rat
cellular response to insulin stimulusGO:0032869780.011
positive regulation of protein transportGO:0051222930.011
regulation of lymphocyte differentiationGO:00456191070.011
regulation of lymphocyte proliferationGO:00506701170.011
glucose homeostasisGO:00425931280.011
negative regulation of neuron differentiationGO:00456651010.011
Mouse
cellular response to amino acid stimulusGO:0071230290.011
dna repairGO:00062811070.011
negative regulation of proteolysisGO:0045861740.010
covalent chromatin modificationGO:00165691630.010
nucleoside monophosphate metabolic processGO:0009123850.010
rho protein signal transductionGO:0007266320.010
regulation of angiogenesisGO:0045765810.010
protein ubiquitinationGO:00165671710.010
ribonucleoside monophosphate metabolic processGO:0009161800.010
purine containing compound catabolic processGO:00725232130.010
purine ribonucleoside catabolic processGO:00461302050.010
glycosyl compound catabolic processGO:19016582060.010
hormone metabolic processGO:0042445860.010
branching morphogenesis of an epithelial tubeGO:00487541590.010
cytokinetic processGO:003250620.010
axonogenesisGO:00074092740.010
inorganic ion transmembrane transportGO:00986602340.010
striated muscle myosin thick filament assemblyGO:007168810.010
positive regulation of neuron differentiationGO:00456661410.010
organelle assemblyGO:00709251770.010
myosin filament assemblyGO:003103420.010
neuron deathGO:00709971540.010
skin developmentGO:00435882200.010
purine nucleotide metabolic processGO:00061633020.010
adaptive immune responseGO:00022501550.010
organic acid biosynthetic processGO:0016053860.010
response to drugGO:0042493750.010
regulation of lipid biosynthetic processGO:0046890540.010

Klk1b22 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.022
nervous system diseaseDOID:86300.021
disease of anatomical entityDOID:700.021
inherited metabolic disorderDOID:65500.015
central nervous system diseaseDOID:33100.014
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
musculoskeletal system diseaseDOID:1700.012
neurodegenerative diseaseDOID:128900.011
organ system cancerDOID:005068600.011