IMP: Integrative Multi-species Prediction

Mus musculus

29 known processes

Klk1b26

kallikrein 1-related petidase b26

(Aliases: Klk26,mGK-26,Egfbp2,mGK26,PRECE-2)

Entrez: 16618
Ensembl: ENSMUSG00000053719
UniProtKB: P36369

Process Predictions
Disease Predictions

Klk1b26 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
kinin cascade	GO:0002254	2	0.999	Mouse
bradykinin biosynthetic process	GO:0002936	1	0.999	Mouse
tissue kallikrein kinin cascade	GO:0002255	1	0.999	Mouse
negative regulation of neuron projection regeneration	GO:0070571	3	0.996	Mouse
left ventricular cardiac muscle tissue morphogenesis	GO:0003220	2	0.995	Mouse
protein activation cascade	GO:0072376	19	0.981	Mouse
positive regulation of lipid kinase activity	GO:0090218	11	0.964	Mouse
brain renin angiotensin system	GO:0002035	5	0.956
positive regulation of vasoconstriction	GO:0045907	4	0.945	Rat
peptide metabolic process	GO:0006518	46	0.928	Mouse
regulation of blood volume by renin angiotensin	GO:0002016	7	0.916
fertilization	GO:0009566	127	0.914	Mouse
cellular amide metabolic process	GO:0043603	58	0.891	Mouse
regulation of phosphatidylinositol 3 kinase activity	GO:0043551	14	0.887	Mouse
positive regulation of lipid metabolic process	GO:0045834	40	0.865	Mouse
neurological system process involved in regulation of systemic arterial blood pressure	GO:0001976	18	0.853
regulation of systemic arterial blood pressure	GO:0003073	61	0.780
regulation of blood pressure	GO:0008217	93	0.772
binding of sperm to zona pellucida	GO:0007339	34	0.765	Mouse
multicellular organismal signaling	GO:0035637	91	0.753
inflammatory response	GO:0006954	244	0.752	Mouse
circulatory system process	GO:0003013	197	0.692
striated muscle contraction	GO:0006941	45	0.675	Mouse
phospholipid metabolic process	GO:0006644	87	0.665	Mouse
regulation of lipid kinase activity	GO:0043550	14	0.664	Mouse
keratinocyte proliferation	GO:0043616	21	0.659	Mouse
regulation of systemic arterial blood pressure by renin angiotensin	GO:0003081	20	0.657
muscle contraction	GO:0006936	101	0.639	Mouse
regulation of response to wounding	GO:1903034	189	0.637	Mouse
positive regulation of phosphatidylinositol 3 kinase activity	GO:0043552	11	0.636	Mouse
ensheathment of neurons	GO:0007272	76	0.621	Mouse
cardiac left ventricle morphogenesis	GO:0003214	9	0.606	Mouse
cell cell recognition	GO:0009988	44	0.604	Mouse
sperm egg recognition	GO:0035036	37	0.602	Mouse
peptide biosynthetic process	GO:0043043	11	0.597	Mouse
regulation of myelination	GO:0031641	20	0.583	Mouse
vascular process in circulatory system	GO:0003018	62	0.564	Mouse Rat
regulation of lipid metabolic process	GO:0019216	118	0.557	Mouse
neuronal action potential	GO:0019228	54	0.530
single fertilization	GO:0007338	82	0.509	Mouse
cellular lipid metabolic process	GO:0044255	323	0.503	Mouse
regulation of neuron projection regeneration	GO:0070570	7	0.498	Mouse
heart contraction	GO:0060047	93	0.493	Mouse
small gtpase mediated signal transduction	GO:0007264	97	0.491	Mouse
action potential	GO:0001508	78	0.479
negative regulation of nervous system development	GO:0051961	156	0.475	Mouse
cardiac muscle tissue morphogenesis	GO:0055008	44	0.471	Mouse
endocrine process	GO:0050886	39	0.470
regulation of systemic arterial blood pressure by hormone	GO:0001990	25	0.464
muscle system process	GO:0003012	141	0.457	Mouse
regulation of blood circulation	GO:1903522	93	0.444	Rat
heart process	GO:0003015	94	0.435	Mouse
regulation of membrane potential	GO:0042391	192	0.433
transmission of nerve impulse	GO:0019226	76	0.431
cardiac muscle contraction	GO:0060048	32	0.429	Mouse
regulation of systemic arterial blood pressure mediated by a chemical signal	GO:0003044	33	0.424
cardiac ventricle morphogenesis	GO:0003208	50	0.411	Mouse
learning or memory	GO:0007611	148	0.399	Mouse
ventricular cardiac muscle tissue morphogenesis	GO:0055010	32	0.393	Mouse
vasoconstriction	GO:0042310	27	0.382	Rat
protein catabolic process	GO:0030163	221	0.376	Mouse
cell recognition	GO:0008037	83	0.375	Mouse
acute inflammatory response	GO:0002526	41	0.374	Mouse
protein maturation	GO:0051604	176	0.373
axon ensheathment	GO:0008366	76	0.373	Mouse
cardiac chamber morphogenesis	GO:0003206	93	0.353	Mouse
negative regulation of cell development	GO:0010721	169	0.352	Mouse
positive regulation of blood circulation	GO:1903524	22	0.345	Rat
organonitrogen compound biosynthetic process	GO:1901566	192	0.344	Mouse
positive regulation of kinase activity	GO:0033674	155	0.317	Mouse
myelination	GO:0042552	74	0.316	Mouse
neuron projection regeneration	GO:0031102	14	0.293	Mouse
macromolecule catabolic process	GO:0009057	281	0.291	Mouse
zymogen activation	GO:0031638	41	0.290
amelogenesis	GO:0097186	12	0.286	Mouse
protein processing	GO:0016485	163	0.285
negative regulation of neuron differentiation	GO:0045665	101	0.280	Mouse
synapse organization	GO:0050808	125	0.257	Mouse
regulation of vasoconstriction	GO:0019229	14	0.253	Rat
regulation of neuron projection development	GO:0010975	169	0.250	Mouse
vasodilation	GO:0042311	28	0.249	Mouse
cardiac ventricle development	GO:0003231	83	0.234	Mouse
muscle tissue development	GO:0060537	308	0.231	Mouse
memory	GO:0007613	58	0.221	Mouse
heart morphogenesis	GO:0003007	178	0.208	Mouse
negative regulation of cell projection organization	GO:0031345	56	0.204	Mouse
regulation of transferase activity	GO:0051338	263	0.203	Mouse
negative regulation of neuron projection development	GO:0010977	50	0.201	Mouse
regulation of neuron differentiation	GO:0045664	281	0.196	Mouse
muscle tissue morphogenesis	GO:0060415	53	0.188	Mouse
extracellular structure organization	GO:0043062	148	0.186	Mouse
negative regulation of cellular component organization	GO:0051129	194	0.176	Mouse
negative regulation of response to wounding	GO:1903035	77	0.173	Mouse
epithelial cell proliferation	GO:0050673	174	0.172	Mouse
striated muscle tissue development	GO:0014706	293	0.171	Mouse
regulation of kinase activity	GO:0043549	249	0.167	Mouse
extracellular matrix organization	GO:0030198	147	0.166	Mouse
cognition	GO:0050890	149	0.166	Mouse
cellular chemical homeostasis	GO:0055082	215	0.165
ventricular cardiac muscle tissue development	GO:0003229	38	0.162	Mouse
cardiac chamber development	GO:0003205	108	0.160	Mouse
heterocycle catabolic process	GO:0046700	280	0.157
cellular response to organonitrogen compound	GO:0071417	145	0.157
regulation of neurological system process	GO:0031644	22	0.154	Mouse
axon regeneration	GO:0031103	12	0.154	Mouse
purine nucleoside catabolic process	GO:0006152	205	0.153
nitrogen compound transport	GO:0071705	271	0.151
regulation of cell projection organization	GO:0031344	206	0.145	Mouse
mitochondrion organization	GO:0007005	134	0.145
amine metabolic process	GO:0009308	45	0.144
cardiac muscle tissue development	GO:0048738	130	0.144	Mouse
positive regulation of transferase activity	GO:0051347	167	0.134	Mouse
chemotaxis	GO:0006935	247	0.132
positive regulation of thymocyte migration	GO:2000412	2	0.129
regulation of tube size	GO:0035150	57	0.120	Mouse Rat
cation transport	GO:0006812	399	0.119
regulation of system process	GO:0044057	200	0.116	Mouse Rat
blood circulation	GO:0008015	195	0.111
cellular amine metabolic process	GO:0044106	44	0.100
granzyme mediated apoptotic signaling pathway	GO:0008626	1	0.099
odontogenesis	GO:0042476	78	0.098	Mouse
organic cyclic compound catabolic process	GO:1901361	295	0.087
divalent metal ion transport	GO:0070838	172	0.087
regeneration	GO:0031099	38	0.082	Mouse
regulation of transmembrane transport	GO:0034762	128	0.081
positive regulation of eosinophil migration	GO:2000418	2	0.080
regulation of eosinophil migration	GO:2000416	2	0.080
negative regulation of insulin secretion involved in cellular response to glucose stimulus	GO:0061179	4	0.075
purine ribonucleotide metabolic process	GO:0009150	290	0.074
regulation of cellular response to stress	GO:0080135	159	0.074	Mouse
regulation of t helper 1 cell cytokine production	GO:2000554	1	0.074
nucleoside phosphate catabolic process	GO:1901292	222	0.072
cation transmembrane transport	GO:0098655	266	0.072
regulation of angiotensin levels in blood	GO:0002002	4	0.069
purine containing compound catabolic process	GO:0072523	213	0.067
t helper 2 cell cytokine production	GO:0035745	4	0.067
eosinophil migration	GO:0072677	3	0.066
purine nucleoside metabolic process	GO:0042278	241	0.066
skin development	GO:0043588	220	0.065
cellular homeostasis	GO:0019725	240	0.063
regulation of neurotransmitter levels	GO:0001505	87	0.062
amide transport	GO:0042886	138	0.062
peptide transport	GO:0015833	133	0.062
cellular ion homeostasis	GO:0006873	165	0.061
regulation of secretion by cell	GO:1903530	249	0.060
regulation of blood vessel size	GO:0050880	56	0.059	Mouse Rat
neutrophil mediated killing of gram positive bacterium	GO:0070946	2	0.058
amide biosynthetic process	GO:0043604	16	0.057	Mouse
regulation of body fluid levels	GO:0050878	162	0.056
male gamete generation	GO:0048232	285	0.055
regulation of proteolysis	GO:0030162	164	0.055
regulation of anatomical structure size	GO:0090066	178	0.053	Mouse Rat
cellular amino acid metabolic process	GO:0006520	103	0.053
cation homeostasis	GO:0055080	212	0.051
cellular response to food	GO:0071240	1	0.050
sensory perception	GO:0007600	245	0.050
transmembrane transport	GO:0055085	412	0.049
multicellular organismal homeostasis	GO:0048871	164	0.049
negative regulation of cellular protein metabolic process	GO:0032269	247	0.049
organophosphate catabolic process	GO:0046434	232	0.047
maintenance of location	GO:0051235	89	0.046
organonitrogen compound catabolic process	GO:1901565	264	0.046
nucleotide metabolic process	GO:0009117	332	0.045
tissue homeostasis	GO:0001894	115	0.045
negative regulation of myelination	GO:0031642	6	0.045	Mouse
ribonucleoside metabolic process	GO:0009119	245	0.045
synaptic transmission	GO:0007268	329	0.043	Mouse
cellular response to steroid hormone stimulus	GO:0071383	33	0.042
thymocyte migration	GO:0072679	2	0.042
nucleobase containing small molecule metabolic process	GO:0055086	352	0.042
regulation of t cell activation	GO:0050863	170	0.042
negative regulation of neurological system process	GO:0031645	7	0.042	Mouse
odontogenesis of dentin containing tooth	GO:0042475	66	0.042	Mouse
negative regulation of protein metabolic process	GO:0051248	282	0.042
engulfment of apoptotic cell	GO:0043652	3	0.041
hexose metabolic process	GO:0019318	98	0.040
cellular response to hormone stimulus	GO:0032870	150	0.040
response to nutrient levels	GO:0031667	109	0.040
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.040
purine nucleotide catabolic process	GO:0006195	211	0.038
purine nucleotide metabolic process	GO:0006163	302	0.038
regulation of lymphocyte differentiation	GO:0045619	107	0.038
response to organic cyclic compound	GO:0014070	198	0.038
positive regulation of protein phosphorylation	GO:0001934	242	0.037
regulation of lymphocyte activation	GO:0051249	240	0.037
sequestering of metal ion	GO:0051238	19	0.037
muscle fiber development	GO:0048747	76	0.036
nucleotide catabolic process	GO:0009166	217	0.036
cellular response to peptide hormone stimulus	GO:0071375	92	0.036
regulation of thymocyte migration	GO:2000410	2	0.036
anatomical structure homeostasis	GO:0060249	145	0.035
lipid biosynthetic process	GO:0008610	179	0.035
ribonucleotide catabolic process	GO:0009261	208	0.034
positive regulation of cell development	GO:0010720	237	0.034
leukocyte homeostasis	GO:0001776	79	0.034
calcium ion transport	GO:0006816	159	0.034
oxidation reduction process	GO:0055114	342	0.033
potassium ion homeostasis	GO:0055075	4	0.033
purine ribonucleoside catabolic process	GO:0046130	205	0.033
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.033
epidermis development	GO:0008544	187	0.033
cellular response to lipid	GO:0071396	145	0.033
purine containing compound metabolic process	GO:0072521	311	0.033
muscle cell differentiation	GO:0042692	261	0.033
negative regulation of peptide hormone secretion	GO:0090278	16	0.033
axonogenesis	GO:0007409	274	0.033
myotube cell development	GO:0014904	60	0.032
spermatid differentiation	GO:0048515	115	0.032
rhythmic process	GO:0048511	174	0.032
response to acid chemical	GO:0001101	111	0.032
response to oxidative stress	GO:0006979	123	0.031
divalent inorganic cation transport	GO:0072511	178	0.031
regulation of cellular amine metabolic process	GO:0033238	20	0.031
response to lipopolysaccharide	GO:0032496	128	0.031
regulation of cellular catabolic process	GO:0031329	242	0.031
cellular response to monosaccharide stimulus	GO:0071326	47	0.030
spermatogenesis	GO:0007283	284	0.030
metal ion homeostasis	GO:0055065	189	0.030
glycosyl compound metabolic process	GO:1901657	246	0.030
negative regulation of molecular function	GO:0044092	258	0.030
cellular response to external stimulus	GO:0071496	88	0.030
response to insulin	GO:0032868	100	0.030
regulation of cell cycle	GO:0051726	281	0.030
carbohydrate derivative catabolic process	GO:1901136	231	0.029
inorganic ion transmembrane transport	GO:0098660	234	0.029
organelle fission	GO:0048285	170	0.029
positive regulation of programmed cell death	GO:0043068	218	0.029
ribonucleoside catabolic process	GO:0042454	206	0.029
cellular response to organic cyclic compound	GO:0071407	87	0.029
olfactory learning	GO:0008355	2	0.029
response to steroid hormone	GO:0048545	56	0.029
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.028
regulation of peptide hormone secretion	GO:0090276	75	0.028
nucleoside triphosphate catabolic process	GO:0009143	205	0.028
response to organonitrogen compound	GO:0010243	246	0.028
regulation of skeletal muscle fiber development	GO:0048742	36	0.028
calcium ion homeostasis	GO:0055074	127	0.027
regulation of peptide transport	GO:0090087	91	0.027
regulation of angiotensin metabolic process	GO:0060177	4	0.027
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.027
negative regulation of cell proliferation	GO:0008285	296	0.026
cellular response to peptide	GO:1901653	92	0.026
phosphatidylethanolamine biosynthetic process	GO:0006646	2	0.026
learning	GO:0007612	98	0.026
nucleoside triphosphate metabolic process	GO:0009141	230	0.026
cellular ketone metabolic process	GO:0042180	84	0.026
nucleoside metabolic process	GO:0009116	246	0.026
response to peptide	GO:1901652	136	0.026
adaptive immune response	GO:0002250	155	0.026
regulation of purine nucleotide metabolic process	GO:1900542	169	0.025
response to starvation	GO:0042594	65	0.025
divalent inorganic cation homeostasis	GO:0072507	138	0.025
g protein coupled receptor signaling pathway	GO:0007186	243	0.025
cellular carbohydrate metabolic process	GO:0044262	119	0.025
nucleoside catabolic process	GO:0009164	206	0.025
production of molecular mediator of immune response	GO:0002440	103	0.025
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.025
cellular response to extracellular stimulus	GO:0031668	81	0.024
aromatic compound catabolic process	GO:0019439	286	0.024
glycerophospholipid metabolic process	GO:0006650	71	0.024	Mouse
regulation of nucleotide metabolic process	GO:0006140	169	0.024
regulation of vesicle mediated transport	GO:0060627	139	0.024
lymphocyte differentiation	GO:0030098	242	0.023
organophosphate biosynthetic process	GO:0090407	122	0.023
cellular metal ion homeostasis	GO:0006875	151	0.023
locomotory behavior	GO:0007626	195	0.023
cd4 positive alpha beta t cell cytokine production	GO:0035743	4	0.023
negative regulation of insulin secretion	GO:0046676	14	0.023
regulation of hormone levels	GO:0010817	211	0.023
glycerolipid biosynthetic process	GO:0045017	50	0.023
regulation of cell activation	GO:0050865	289	0.023
regulation of t helper 2 cell cytokine production	GO:2000551	3	0.023
lymphocyte mediated immunity	GO:0002449	139	0.023
ribonucleotide metabolic process	GO:0009259	291	0.023
regulation of ion transmembrane transport	GO:0034765	119	0.022
t cell activation	GO:0042110	289	0.022
t helper 1 cell cytokine production	GO:0035744	1	0.022
response to monosaccharide	GO:0034284	67	0.022
cellular response to testosterone stimulus	GO:0071394	1	0.022
carbohydrate metabolic process	GO:0005975	230	0.022
t cell mediated immunity	GO:0002456	50	0.022
macromolecule methylation	GO:0043414	120	0.021
tissue remodeling	GO:0048771	102	0.021
muscle cell development	GO:0055001	133	0.021
gland development	GO:0048732	330	0.021
positive regulation of cd4 positive alpha beta t cell proliferation	GO:2000563	1	0.021
neuron death	GO:0070997	154	0.021
cytokine production	GO:0001816	319	0.021
regulation of antimicrobial humoral response	GO:0002759	3	0.021
positive regulation of cell death	GO:0010942	224	0.021
regulation of homeostatic process	GO:0032844	182	0.021
cellular response to starvation	GO:0009267	57	0.021
purine ribonucleotide catabolic process	GO:0009154	208	0.021
carbohydrate biosynthetic process	GO:0016051	74	0.021
response to extracellular stimulus	GO:0009991	127	0.021
response to hypoxia	GO:0001666	58	0.021
gonad development	GO:0008406	141	0.021
regulation of natural killer cell chemotaxis	GO:2000501	1	0.020
positive regulation of neuron apoptotic process	GO:0043525	25	0.020
ribose phosphate metabolic process	GO:0019693	291	0.020
cellular nitrogen compound catabolic process	GO:0044270	280	0.020
positive regulation of protein kinase activity	GO:0045860	144	0.020
wound healing	GO:0042060	157	0.020
regulation of organelle organization	GO:0033043	289	0.020
multicellular organism growth	GO:0035264	161	0.020
skeletal muscle organ development	GO:0060538	163	0.020
homeostasis of number of cells	GO:0048872	210	0.020
purine ribonucleoside metabolic process	GO:0046128	241	0.020
protein localization to organelle	GO:0033365	185	0.019
sequestering of calcium ion	GO:0051208	18	0.019
positive regulation of hydrolase activity	GO:0051345	148	0.019
regulation of adaptive immune response	GO:0002819	90	0.019
neuron apoptotic process	GO:0051402	142	0.019
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.019
regulation of hormone secretion	GO:0046883	88	0.019
regulation of peptide secretion	GO:0002791	77	0.019
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.019
monosaccharide metabolic process	GO:0005996	106	0.019
defense response to other organism	GO:0098542	197	0.019
response to molecule of bacterial origin	GO:0002237	143	0.019
glucose homeostasis	GO:0042593	128	0.019
membrane lipid biosynthetic process	GO:0046467	32	0.019
interspecies interaction between organisms	GO:0044419	83	0.018
glycosyl compound catabolic process	GO:1901658	206	0.018
methylation	GO:0032259	134	0.018
regulation of cell adhesion	GO:0030155	154	0.018
reactive oxygen species metabolic process	GO:0072593	84	0.018
positive regulation of cellular catabolic process	GO:0031331	148	0.018
mitotic nuclear division	GO:0007067	48	0.018
circadian rhythm	GO:0007623	114	0.018
cellular calcium ion homeostasis	GO:0006874	119	0.018
modification of morphology or physiology of other organism involved in symbiotic interaction	GO:0051817	16	0.018
membrane organization	GO:0061024	245	0.018
regulation of multi organism process	GO:0043900	111	0.018
guanosine containing compound catabolic process	GO:1901069	144	0.018
positive regulation of leukocyte mediated immunity	GO:0002705	70	0.017
negative regulation of hormone secretion	GO:0046888	20	0.017
myotube differentiation	GO:0014902	105	0.017
developmental maturation	GO:0021700	193	0.017
regulation of circadian sleep wake cycle sleep	GO:0045187	3	0.017
ear development	GO:0043583	200	0.017
regulation of hydrolase activity	GO:0051336	246	0.017
dephosphorylation	GO:0016311	129	0.017
regulation of circadian sleep wake cycle	GO:0042749	3	0.017
second messenger mediated signaling	GO:0019932	73	0.017
actin mediated cell contraction	GO:0070252	15	0.017
modification by host of symbiont morphology or physiology	GO:0051851	12	0.017
inorganic cation transmembrane transport	GO:0098662	207	0.017
response to oxygen levels	GO:0070482	62	0.017
germ cell development	GO:0007281	185	0.017
regulation of defense response	GO:0031347	233	0.016
cell type specific apoptotic process	GO:0097285	268	0.016
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002822	87	0.016
multicellular organismal water homeostasis	GO:0050891	23	0.016
cellular glucose homeostasis	GO:0001678	52	0.016
positive regulation of cellular amine metabolic process	GO:0033240	5	0.016
response to reactive oxygen species	GO:0000302	56	0.016
blastocyst development	GO:0001824	80	0.016
positive regulation of apoptotic process	GO:0043065	217	0.016
skeletal system development	GO:0001501	356	0.016
response to inactivity	GO:0014854	4	0.016
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.016
positive regulation of antimicrobial humoral response	GO:0002760	2	0.016
response to amino acid	GO:0043200	37	0.016
regulation of cellular amino acid metabolic process	GO:0006521	5	0.016
mitotic cell cycle process	GO:1903047	159	0.016
immunoglobulin production involved in immunoglobulin mediated immune response	GO:0002381	43	0.016
regulation of inward rectifier potassium channel activity	GO:1901979	1	0.016
cellular response to glucose stimulus	GO:0071333	45	0.016
regulation of epithelial cell proliferation	GO:0050678	141	0.016
lung development	GO:0030324	164	0.016
positive regulation of t helper 1 cell cytokine production	GO:2000556	1	0.016
response to testosterone	GO:0033574	3	0.016
negative regulation of cellular amine metabolic process	GO:0033239	1	0.016
cell cell junction organization	GO:0045216	72	0.016
striated muscle cell development	GO:0055002	125	0.015
regulation of engulfment of apoptotic cell	GO:1901074	2	0.015
antibacterial peptide production	GO:0002778	2	0.015
positive regulation of protein transport	GO:0051222	93	0.015
regulation of cd4 positive alpha beta t cell proliferation	GO:2000561	2	0.015
glycerophospholipid biosynthetic process	GO:0046474	32	0.015
cell fate commitment	GO:0045165	210	0.015
gtp catabolic process	GO:0006184	143	0.015
regulation of glucose metabolic process	GO:0010906	60	0.015
negative regulation of multi organism process	GO:0043901	68	0.015
positive regulation of antimicrobial peptide biosynthetic process	GO:0002807	1	0.015
central nervous system neuron differentiation	GO:0021953	162	0.014
single organismal cell cell adhesion	GO:0016337	131	0.014
myeloid cell differentiation	GO:0030099	233	0.014
potassium ion transmembrane transport	GO:0071805	43	0.014
digestion	GO:0007586	40	0.014
immune effector process	GO:0002252	321	0.014
sphingolipid biosynthetic process	GO:0030148	26	0.014
developmental growth involved in morphogenesis	GO:0060560	138	0.014
regulation of mapk cascade	GO:0043408	248	0.014
multi multicellular organism process	GO:0044706	109	0.014
cell maturation	GO:0048469	127	0.014
oligopeptide transmembrane transport	GO:0035672	4	0.014
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.014
cellular response to cytokine stimulus	GO:0071345	189	0.014
positive regulation of neuron death	GO:1901216	28	0.014
positive regulation of natural killer cell chemotaxis	GO:2000503	1	0.014
rna interference	GO:0016246	2	0.014
modification of morphology or physiology of other organism	GO:0035821	18	0.013
regulation of nucleotide catabolic process	GO:0030811	122	0.013
positive regulation of dendritic cell dendrite assembly	GO:2000549	1	0.013
leukocyte mediated immunity	GO:0002443	174	0.013
mitral valve development	GO:0003174	4	0.013
fatty acid biosynthetic process	GO:0006633	41	0.013
regulation of cellular ketone metabolic process	GO:0010565	66	0.013
cell adhesion	GO:0007155	329	0.013
regulation of inflammatory response	GO:0050727	147	0.013
myeloid cell homeostasis	GO:0002262	114	0.013
regulation of g protein activated inward rectifier potassium channel activity	GO:1900128	1	0.013
neuron projection guidance	GO:0097485	141	0.013
cellular response to insulin stimulus	GO:0032869	78	0.013
cell chemotaxis	GO:0060326	81	0.013
cellular response to oxidative stress	GO:0034599	76	0.013
apoptotic signaling pathway	GO:0097190	306	0.013
monocarboxylic acid metabolic process	GO:0032787	191	0.013
multicellular organismal response to stress	GO:0033555	62	0.013
regulation of protein catabolic process	GO:0042176	108	0.013
reactive nitrogen species metabolic process	GO:2001057	0	0.013
regulation of ion transport	GO:0043269	215	0.013
compound eye development	GO:0048749	1	0.013
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.012
regulation of endocytosis	GO:0030100	69	0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.012
regulation of striated muscle cell differentiation	GO:0051153	81	0.012
killing by host of symbiont cells	GO:0051873	11	0.012
negative regulation of phosphorylation	GO:0042326	166	0.012
actin filament based movement	GO:0030048	23	0.012
cellular response to carbohydrate stimulus	GO:0071322	50	0.012
mature natural killer cell chemotaxis	GO:0035782	1	0.012
nucleoside phosphate metabolic process	GO:0006753	338	0.012
response to inorganic substance	GO:0010035	96	0.012
calcium ion transmembrane transport	GO:0070588	85	0.012
negative regulation of leukocyte apoptotic process	GO:2000107	31	0.012
negative regulation of peptide secretion	GO:0002792	16	0.012
renal system process	GO:0003014	48	0.012
membrane depolarization	GO:0051899	64	0.012
regulation of t cell differentiation	GO:0045580	83	0.012
regulation of myotube differentiation	GO:0010830	62	0.012
catecholamine uptake	GO:0090493	4	0.012
peptide secretion	GO:0002790	114	0.012
regulation of purine nucleotide catabolic process	GO:0033121	122	0.012
phospholipid biosynthetic process	GO:0008654	36	0.012
response to food	GO:0032094	17	0.012
regulation of monocyte chemotaxis	GO:0090025	3	0.012
actin cytoskeleton organization	GO:0030036	220	0.012
renal sodium ion transport	GO:0003096	2	0.012
regulation of microvillus organization	GO:0032530	3	0.012
feeding behavior	GO:0007631	62	0.012
peptidyl amino acid modification	GO:0018193	336	0.011
negative regulation of homeostatic process	GO:0032845	71	0.011
bone morphogenesis	GO:0060349	78	0.011
respiratory system development	GO:0060541	190	0.011
positive regulation of cell cycle	GO:0045787	92	0.011
regulation of lipid biosynthetic process	GO:0046890	54	0.011
regulation of myoblast differentiation	GO:0045661	29	0.011
cellularization	GO:0007349	1	0.011
ossification	GO:0001503	216	0.011
neurotransmitter transport	GO:0006836	76	0.011
positive regulation of nervous system development	GO:0051962	221	0.011
disruption by host of symbiont cells	GO:0051852	11	0.011
detection of chemical stimulus involved in sensory perception of taste	GO:0050912	3	0.011
cellular response to hexose stimulus	GO:0071331	47	0.011
regulation of cytokine production	GO:0001817	266	0.011
body fluid secretion	GO:0007589	53	0.011
gluconeogenesis	GO:0006094	39	0.011
atp metabolic process	GO:0046034	75	0.010
peptide hormone secretion	GO:0030072	109	0.010
disruption of cells of other organism involved in symbiotic interaction	GO:0051818	13	0.010
phenol containing compound metabolic process	GO:0018958	60	0.010
ceramide biosynthetic process	GO:0046513	20	0.010
small molecule biosynthetic process	GO:0044283	132	0.010
t helper cell differentiation	GO:0042093	28	0.010
positive regulation of proteolysis	GO:0045862	85	0.010
positive regulation of protein modification process	GO:0031401	299	0.010
glial cell development	GO:0021782	54	0.010
monovalent inorganic cation homeostasis	GO:0055067	33	0.010
activation of mapk activity involved in innate immune response	GO:0035419	2	0.010
regulation of vitamin metabolic process	GO:0030656	3	0.010
regulation of secretion	GO:0051046	274	0.010
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway	GO:0051482	4	0.010

Klk1b26 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.017
inherited metabolic disorder	DOID:655	0.016
disease of anatomical entity	DOID:7	0.013
nervous system disease	DOID:863	0.013

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