Mus musculus

81 known processes

Pde3b

phosphodiesterase 3B, cGMP-inhibited

(Aliases: AI847709,9830102A01Rik)

Pde3b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442553230.080
Rat
amine metabolic processGO:0009308450.072
cellular amino acid metabolic processGO:00065201030.070
cellular amine metabolic processGO:0044106440.061
regulation of cellular amino acid metabolic processGO:000652150.055
nucleotide metabolic processGO:00091173320.052
Human Rat
transmembrane transportGO:00550854120.052
heterocycle catabolic processGO:00467002800.051
Human Rat
regulation of cellular amine metabolic processGO:0033238200.051
small gtpase mediated signal transductionGO:0007264970.050
nucleobase containing small molecule metabolic processGO:00550863520.049
Human Rat
purine nucleotide metabolic processGO:00061633020.046
Human Rat
cellular ketone metabolic processGO:0042180840.046
organic cyclic compound catabolic processGO:19013612950.046
Human Rat
anion transportGO:00068201770.045
organonitrogen compound catabolic processGO:19015652640.044
Human Rat
purine ribonucleotide metabolic processGO:00091502900.044
Human Rat
ribose phosphate metabolic processGO:00196932910.043
Human Rat
ras protein signal transductionGO:0007265770.043
regulation of cellular ketone metabolic processGO:0010565660.043
positive regulation of cellular amine metabolic processGO:003324050.041
positive regulation of cellular amino acid metabolic processGO:004576430.040
negative regulation of protein metabolic processGO:00512482820.039
lipid biosynthetic processGO:00086101790.038
oxidation reduction processGO:00551143420.038
negative regulation of molecular functionGO:00440922580.037
nitrogen compound transportGO:00717052710.037
cellular nitrogen compound catabolic processGO:00442702800.035
Human Rat
aromatic compound catabolic processGO:00194392860.035
Human Rat
nucleoside phosphate metabolic processGO:00067533380.035
Human Rat
cation transportGO:00068123990.034
carboxylic acid biosynthetic processGO:0046394860.034
purine containing compound metabolic processGO:00725213110.033
Human Rat
leukocyte differentiationGO:00025213420.033
response to organonitrogen compoundGO:00102432460.033
negative regulation of phosphorus metabolic processGO:00105631840.033
mapk cascadeGO:00001652810.032
monocarboxylic acid metabolic processGO:00327871910.032
ribonucleotide metabolic processGO:00092592910.032
Human Rat
ion transmembrane transportGO:00342203610.032
negative regulation of cellular protein metabolic processGO:00322692470.031
organonitrogen compound biosynthetic processGO:19015661920.031
carbohydrate derivative biosynthetic processGO:19011371830.031
carbohydrate metabolic processGO:00059752300.031
regulation of transferase activityGO:00513382630.030
carbohydrate derivative catabolic processGO:19011362310.029
Human Rat
purine ribonucleoside metabolic processGO:00461282410.029
organic acid biosynthetic processGO:0016053860.029
lymphocyte differentiationGO:00300982420.029
organophosphate catabolic processGO:00464342320.029
Human Rat
ribonucleoside metabolic processGO:00091192450.029
spermatogenesisGO:00072832840.029
glycosyl compound metabolic processGO:19016572460.028
peptidyl amino acid modificationGO:00181933360.028
purine ribonucleoside triphosphate metabolic processGO:00092052200.028
purine ribonucleotide catabolic processGO:00091542080.028
Human Rat
cellular chemical homeostasisGO:00550822150.028
negative regulation of phosphate metabolic processGO:00459361840.027
purine nucleoside metabolic processGO:00422782410.027
cytokine productionGO:00018163190.027
ribonucleoside triphosphate metabolic processGO:00091992200.027
regulation of membrane potentialGO:00423911920.027
dna metabolic processGO:00062593030.027
purine nucleotide catabolic processGO:00061952110.027
Human Rat
small molecule biosynthetic processGO:00442831320.027
nucleotide catabolic processGO:00091662170.027
Human Rat
cellular homeostasisGO:00197252400.027
nucleoside metabolic processGO:00091162460.026
regulation of hydrolase activityGO:00513362460.026
nucleoside phosphate catabolic processGO:19012922220.026
Human Rat
cation transmembrane transportGO:00986552660.026
regulation of kinase activityGO:00435492490.026
cellular response to organonitrogen compoundGO:00714171450.026
nucleoside triphosphate metabolic processGO:00091412300.026
regulation of mapk cascadeGO:00434082480.025
ribonucleotide catabolic processGO:00092612080.025
Human Rat
regulation of neuron differentiationGO:00456642810.025
male gamete generationGO:00482322850.025
regulation of cellular catabolic processGO:00313292420.025
cytoplasmic transportGO:00164822340.025
regulation of lymphocyte activationGO:00512492400.025
immune effector processGO:00022523210.025
purine ribonucleoside catabolic processGO:00461302050.025
regulation of cell activationGO:00508652890.025
regulation of system processGO:00440572000.024
negative regulation of phosphorylationGO:00423261660.024
fat cell differentiationGO:00454441600.024
regulation of organelle organizationGO:00330432890.024
Mouse
ribonucleoside triphosphate catabolic processGO:00092031990.024
posttranscriptional regulation of gene expressionGO:00106081550.024
protein maturationGO:00516041760.023
apoptotic signaling pathwayGO:00971903060.023
nucleoside triphosphate catabolic processGO:00091432050.023
fatty acid metabolic processGO:00066311210.023
nuclear divisionGO:00002801580.023
Mouse
glycerolipid metabolic processGO:00464861220.023
positive regulation of protein modification processGO:00314012990.023
regulation of hormone levelsGO:00108172110.022
nucleoside catabolic processGO:00091642060.022
regulation of nucleotide metabolic processGO:00061401690.022
organic hydroxy compound metabolic processGO:19016152030.022
purine containing compound catabolic processGO:00725232130.022
Human Rat
forebrain developmentGO:00309003020.022
purine nucleoside triphosphate metabolic processGO:00091442260.022
sensory perceptionGO:00076002450.022
respiratory system developmentGO:00605411900.022
purine ribonucleoside triphosphate catabolic processGO:00092071990.022
multicellular organism growthGO:00352641610.021
purine nucleoside triphosphate catabolic processGO:00091462030.021
regulation of protein kinase activityGO:00458592320.021
organophosphate biosynthetic processGO:00904071220.021
g protein coupled receptor signaling pathwayGO:00071862430.021
protein processingGO:00164851630.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.021
glycosyl compound catabolic processGO:19016582060.021
regulation of defense responseGO:00313472330.021
positive regulation of protein phosphorylationGO:00019342420.021
organic anion transportGO:00157111370.021
organelle fissionGO:00482851700.021
Mouse
muscle system processGO:00030121410.020
camera type eye developmentGO:00430102660.020
negative regulation of protein modification processGO:00314001630.020
purine nucleoside catabolic processGO:00061522050.020
inorganic cation transmembrane transportGO:00986622070.020
t cell activationGO:00421102890.020
regulation of secretionGO:00510462740.020
cation homeostasisGO:00550802120.020
skeletal system developmentGO:00015013560.020
regulation of cytokine productionGO:00018172660.019
negative regulation of immune system processGO:00026832090.019
ribonucleoside catabolic processGO:00424542060.019
muscle contractionGO:00069361010.019
blood circulationGO:00080151950.019
circulatory system processGO:00030131970.019
cell type specific apoptotic processGO:00972852680.019
membrane organizationGO:00610242450.019
chromatin organizationGO:00063252060.019
locomotory behaviorGO:00076261950.019
rho protein signal transductionGO:0007266320.019
negative regulation of cellular amine metabolic processGO:003323910.019
epithelial cell developmentGO:00020641590.019
cellular response to hormone stimulusGO:00328701500.018
respiratory tube developmentGO:00303231670.018
protein ubiquitinationGO:00165671710.018
regulation of nucleotide catabolic processGO:00308111220.018
muscle cell differentiationGO:00426922610.018
regulation of ras protein signal transductionGO:00465781140.018
negative regulation of cellular component organizationGO:00511291940.018
alcohol metabolic processGO:00060661160.018
glycoprotein metabolic processGO:00091001160.018
protein modification by small protein conjugationGO:00324461870.018
intracellular protein transportGO:00068862040.017
regulation of leukocyte differentiationGO:19021051590.017
inflammatory responseGO:00069542440.017
regulation of apoptotic signaling pathwayGO:20012331970.017
negative regulation of cell proliferationGO:00082852960.017
positive regulation of cell developmentGO:00107202370.017
Mouse
response to molecule of bacterial originGO:00022371430.017
regulation of cell projection organizationGO:00313442060.017
microtubule based processGO:00070172360.017
regulation of purine nucleotide metabolic processGO:19005421690.017
response to peptideGO:19016521360.017
regulation of ion transportGO:00432692150.017
regulation of anatomical structure sizeGO:00900661780.017
muscle tissue developmentGO:00605373080.017
response to organic cyclic compoundGO:00140701980.017
cellular ion homeostasisGO:00068731650.017
macromolecule catabolic processGO:00090572810.017
protein catabolic processGO:00301632210.016
regulation of cell cycleGO:00517262810.016
Mouse
myeloid cell differentiationGO:00300992330.016
regulation of purine nucleotide catabolic processGO:00331211220.016
regulation of secretion by cellGO:19035302490.016
lung developmentGO:00303241640.016
striated muscle tissue developmentGO:00147062930.016
sensory organ morphogenesisGO:00905962420.016
response to lipopolysaccharideGO:00324961280.016
response to radiationGO:00093141650.016
negative regulation of protein phosphorylationGO:00019331260.016
ossificationGO:00015032160.016
monocarboxylic acid biosynthetic processGO:0072330610.016
glucose homeostasisGO:00425931280.016
inorganic ion transmembrane transportGO:00986602340.016
lymphocyte proliferationGO:00466511640.016
compound eye developmentGO:004874910.016
positive regulation of lymphocyte activationGO:00512511400.016
regulation of nucleoside metabolic processGO:00091181300.016
regulation of homeostatic processGO:00328441820.016
positive regulation of cell deathGO:00109422240.016
chromatin modificationGO:00165681870.016
negative regulation of transferase activityGO:0051348850.016
regulation of t cell activationGO:00508631700.016
protein modification by small protein conjugation or removalGO:00706472070.016
regulation of protein serine threonine kinase activityGO:00719001570.016
regulation of cell migrationGO:00303342190.015
negative regulation of intracellular signal transductionGO:19025321670.015
cellular response to lipidGO:00713961450.015
positive regulation of cell activationGO:00508671580.015
protein localization to organelleGO:00333651850.015
gland developmentGO:00487323300.015
mrna metabolic processGO:0016071840.015
response to peptide hormoneGO:00434341270.015
telencephalon developmentGO:00215371860.015
maintenance of locationGO:0051235890.015
positive regulation of cellular catabolic processGO:00313311480.015
positive regulation of nucleoside metabolic processGO:0045979910.015
regulation of protein localizationGO:00328802310.015
calcium ion homeostasisGO:00550741270.015
positive regulation of purine nucleotide metabolic processGO:19005441140.015
small molecule catabolic processGO:0044282710.015
carboxylic acid transportGO:00469421000.015
regulation of establishment of protein localizationGO:00702011810.015
cellular metal ion homeostasisGO:00068751510.015
regulation of cellular component biogenesisGO:00440871810.015
negative regulation of cellular amino acid metabolic processGO:004576300.015
activation of immune responseGO:00022531380.015
cofactor metabolic processGO:0051186800.014
carbohydrate homeostasisGO:00335001280.014
divalent metal ion transportGO:00708381720.014
innate immune responseGO:00450871570.014
b cell activationGO:00421131610.014
regulation of cell motilityGO:20001452360.014
lipid localizationGO:00108761260.014
metal ion homeostasisGO:00550651890.014
meiotic nuclear divisionGO:00071261150.014
Mouse
cell adhesionGO:00071553290.014
Human
action potentialGO:0001508780.014
spermatid differentiationGO:00485151150.014
multicellular organismal homeostasisGO:00488711640.014
t cell differentiationGO:00302171740.014
positive regulation of cytokine productionGO:00018191740.014
positive regulation of nucleotide metabolic processGO:00459811140.014
positive regulation of programmed cell deathGO:00430682180.014
rab protein signal transductionGO:003248210.014
cellular response to biotic stimulusGO:0071216920.014
positive regulation of defense responseGO:00313491240.014
blood vessel morphogenesisGO:00485142850.014
Human
organic acid transportGO:00158491010.014
establishment of protein localization to organelleGO:00725941180.014
transmission of nerve impulseGO:0019226760.014
histone modificationGO:00165701590.014
lipid transportGO:0006869980.014
regulation of response to woundingGO:19030341890.014
cellular component assembly involved in morphogenesisGO:00109271390.014
positive regulation of transferase activityGO:00513471670.014
endomembrane system organizationGO:00102561470.014
sequestering of metal ionGO:0051238190.014
cellular macromolecule catabolic processGO:00442652060.013
skin developmentGO:00435882200.013
organic hydroxy compound transportGO:0015850930.013
developmental maturationGO:00217001930.013
Mouse
cellular response to cytokine stimulusGO:00713451890.013
amide transportGO:00428861380.013
germ cell developmentGO:00072811850.013
Mouse
rna processingGO:00063961050.013
anion transmembrane transportGO:0098656710.013
calcium ion transportGO:00068161590.013
spermatid developmentGO:00072861080.013
positive regulation of apoptotic processGO:00430652170.013
regulation of protein maturationGO:1903317960.013
regulation of ossificationGO:00302781120.013
response to insulinGO:00328681000.013
leukocyte proliferationGO:00706611720.013
rhythmic processGO:00485111740.013
sequestering of calcium ionGO:0051208180.013
embryonic organ morphogenesisGO:00485622760.013
regulation of cellular response to stressGO:00801351590.013
nuclear transportGO:00511691390.013
cellular response to peptide hormone stimulusGO:0071375920.013
regionalizationGO:00030023370.013
anatomical structure homeostasisGO:00602491450.013
guanosine containing compound catabolic processGO:19010691440.013
renal system developmentGO:00720012250.013
purine ribonucleoside monophosphate metabolic processGO:0009167800.013
regulation of intracellular transportGO:00323861590.013
regulation of multi organism processGO:00439001110.013
Mouse
cellular response to dna damage stimulusGO:00069742070.013
positive regulation of mapk cascadeGO:00434101700.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
actin cytoskeleton organizationGO:00300362200.013
response to light stimulusGO:00094161350.013
nucleoside monophosphate metabolic processGO:0009123850.013
mrna processingGO:0006397630.013
fatty acid biosynthetic processGO:0006633410.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
response to oxidative stressGO:00069791230.012
regulation of proteolysisGO:00301621640.012
microtubule cytoskeleton organizationGO:00002261570.012
positive regulation of secretionGO:00510471300.012
positive regulation of hydrolase activityGO:00513451480.012
positive regulation of nervous system developmentGO:00519622210.012
positive regulation of gtpase activityGO:0043547850.012
endocytosisGO:00068971680.012
hematopoietic progenitor cell differentiationGO:00022441430.012
nucleocytoplasmic transportGO:00069131390.012
digestive system developmentGO:00551232000.012
placenta developmentGO:00018901400.012
negative regulation of kinase activityGO:0033673810.012
response to extracellular stimulusGO:00099911270.012
lymphocyte mediated immunityGO:00024491390.012
multicellular organismal signalingGO:0035637910.012
b cell differentiationGO:0030183780.012
positive regulation of innate immune responseGO:0045089800.012
connective tissue developmentGO:00614481790.012
response to inorganic substanceGO:0010035960.012
positive regulation of purine nucleotide catabolic processGO:0033123880.012
synaptic transmissionGO:00072683290.012
guanosine containing compound metabolic processGO:19010681440.012
regulation of vesicle mediated transportGO:00606271390.012
regulation of transmembrane transportGO:00347621280.012
wnt signaling pathwayGO:00160551880.012
rna interferenceGO:001624620.012
multi multicellular organism processGO:00447061090.012
heart contractionGO:0060047930.012
regulation of ras gtpase activityGO:0032318880.012
epithelial tube morphogenesisGO:00605623030.012
wound healingGO:00420601570.012
positive regulation of gtp catabolic processGO:0033126850.012
mitotic cell cycleGO:00002781950.012
adaptive immune responseGO:00022501550.012
peptide transportGO:00158331330.012
organelle assemblyGO:00709251770.012
regulation of body fluid levelsGO:00508781620.012
regulation of lymphocyte differentiationGO:00456191070.012
reactive oxygen species metabolic processGO:0072593840.012
organelle localizationGO:00516401790.012
positive regulation of organelle organizationGO:00106381280.012
sulfur compound metabolic processGO:00067901000.012
negative regulation of cell developmentGO:00107211690.012
positive regulation of protein kinase activityGO:00458601440.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
purine nucleoside monophosphate metabolic processGO:0009126810.011
fertilizationGO:00095661270.011
morphogenesis of a branching epitheliumGO:00611381930.011
cellular carbohydrate metabolic processGO:00442621190.011
cell divisionGO:00513011200.011
Mouse
protein targetingGO:00066051430.011
positive regulation of neuron differentiationGO:00456661410.011
retina development in camera type eyeGO:00600411190.011
regulation of gtp catabolic processGO:00331241130.011
mitotic cell cycle processGO:19030471590.011
development of primary sexual characteristicsGO:00451371430.011
neuronal action potentialGO:0019228540.011
axonogenesisGO:00074092740.011
cellular response to molecule of bacterial originGO:0071219830.011
tissue homeostasisGO:00018941150.011
response to nutrient levelsGO:00316671090.011
regulation of cytoplasmic transportGO:19036491120.011
oocyte constructionGO:000730820.011
neural tube developmentGO:00219151600.011
cellular response to gamma radiationGO:007148040.011
coenzyme biosynthetic processGO:0009108230.011
cell maturationGO:00484691270.011
Mouse
morphogenesis of a branching structureGO:00017632030.011
skeletal system morphogenesisGO:00487052030.011
lateral inhibitionGO:004633110.011
divalent inorganic cation transportGO:00725111780.011
digestive tract developmentGO:00485651900.011
gtp metabolic processGO:00460391440.011
skeletal muscle organ developmentGO:00605381630.011
organic acid catabolic processGO:0016054510.011
monosaccharide metabolic processGO:00059961060.011
acylglycerol metabolic processGO:0006639550.011
cell activation involved in immune responseGO:00022631260.011
divalent inorganic cation homeostasisGO:00725071380.011
positive regulation of growthGO:00459271040.011
regulation of protein transportGO:00512231630.011
gonad developmentGO:00084061410.011
mitochondrion organizationGO:00070051340.011
neuron deathGO:00709971540.011
glycoprotein biosynthetic processGO:0009101890.011
embryonic limb morphogenesisGO:00303261260.011
regulation of protein processingGO:0070613960.011
learning or memoryGO:00076111480.011
epithelial cell proliferationGO:00506731740.011
limb morphogenesisGO:00351081490.011
positive regulation of nucleotide catabolic processGO:0030813880.011
myeloid cell homeostasisGO:00022621140.011
immune response activating signal transductionGO:00027571160.011
protein localization to nucleusGO:00345041210.011
coenzyme metabolic processGO:0006732520.011
homeostasis of number of cellsGO:00488722100.011
cellular response to peptideGO:1901653920.011
cognitionGO:00508901490.011
alpha amino acid metabolic processGO:1901605590.011
midgut developmentGO:000749440.011
positive regulation of kinase activityGO:00336741550.011
cellular calcium ion homeostasisGO:00068741190.011
reactive nitrogen species metabolic processGO:200105700.011
heart morphogenesisGO:00030071780.010
cellular response to growth factor stimulusGO:00713631970.010
regulation of ion transmembrane transportGO:00347651190.010
negative regulation of cell cycleGO:00457861230.010
positive regulation of cellular ph reductionGO:003284920.010
urogenital system developmentGO:00016552610.010
negative regulation of protein maturationGO:1903318790.010
glycosylationGO:0070085620.010
atp metabolic processGO:0046034750.010
limb developmentGO:00601731660.010
cellular response to insulin stimulusGO:0032869780.010
gtp catabolic processGO:00061841430.010
protein importGO:00170381010.010
triglyceride metabolic processGO:0006641510.010
hexose metabolic processGO:0019318980.010
dephosphorylationGO:00163111290.010
oocyte axis specificationGO:000730920.010
cellular protein complex assemblyGO:00436231160.010
response to acid chemicalGO:00011011110.010
defecationGO:003042110.010
regulation of inflammatory responseGO:00507271470.010
meiotic cell cycleGO:00513211220.010
Mouse
peptide hormone secretionGO:00300721090.010
protein localization to membraneGO:00726571080.010
purine containing compound biosynthetic processGO:0072522700.010
negative regulation of protein processingGO:0010955790.010

Pde3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.027
disease of anatomical entityDOID:700.027
disease of metabolismDOID:001466700.025
inherited metabolic disorderDOID:65500.019
eye and adnexa diseaseDOID:149200.015
sensory system diseaseDOID:005015500.015
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
organ system cancerDOID:005068600.014
bone diseaseDOID:008000100.014
musculoskeletal system diseaseDOID:1700.014
connective tissue diseaseDOID:6500.014
immune system diseaseDOID:291400.013
central nervous system diseaseDOID:33100.013
hematopoietic system diseaseDOID:7400.012
eye diseaseDOID:561400.010