Mus musculus

136 known processes

Zap70

zeta-chain (TCR) associated protein kinase

(Aliases: mrtle,Srk,mur,70kDa,AI327364,TZK,ZAP-70)

Zap70 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
leukocyte differentiationGO:00025213420.977
t cell activationGO:00421102890.950
antigen receptor mediated signaling pathwayGO:0050851640.915
immune response activating cell surface receptor signaling pathwayGO:0002429720.805
immune response regulating cell surface receptor signaling pathwayGO:0002768800.769
positive regulation of b cell receptor signaling pathwayGO:005086140.750
regulation of t cell anergyGO:000266740.744
positive regulation of lymphocyte activationGO:00512511400.704
t cell differentiationGO:00302171740.684
regulation of t cell activationGO:00508631700.654
regulation of adaptive immune responseGO:0002819900.648
regulation of lymphocyte activationGO:00512492400.635
regulation of alpha beta t cell activationGO:0046634530.619
immune response activating signal transductionGO:00027571160.615
t cell differentiation in thymusGO:0033077770.582
regulation of response to woundingGO:19030341890.574
Mouse
response to growth factorGO:00708481980.565
regulation of cell activationGO:00508652890.563
somatic recombination of immunoglobulin gene segmentsGO:0016447420.490
amine metabolic processGO:0009308450.488
second messenger mediated signalingGO:0019932730.482
apoptotic signaling pathwayGO:00971903060.455
actin filament organizationGO:00070151130.452
actin polymerization or depolymerizationGO:0008154540.439
regulation of mapk cascadeGO:00434082480.436
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.429
t cell receptor signaling pathwayGO:0050852460.413
regulation of lymphocyte anergyGO:000291140.409
mapk cascadeGO:00001652810.368
Mouse Fly
regulation of hemostasisGO:1900046280.368
Mouse
regulation of actin filament lengthGO:0030832450.357
regulation of actin filament based processGO:0032970990.354
negative regulation of immune system processGO:00026832090.348
positive regulation of t cell anergyGO:000266940.345
actin cytoskeleton organizationGO:00300362200.344
regulation of body fluid levelsGO:00508781620.341
Mouse
negative t cell selectionGO:0043383130.337
dna metabolic processGO:00062593030.337
lymphocyte differentiationGO:00300982420.335
fibroblast growth factor receptor signaling pathwayGO:0008543460.326
alpha beta t cell activationGO:0046631910.322
t cell anergyGO:000287040.303
lymphocyte mediated immunityGO:00024491390.302
activation of immune responseGO:00022531380.301
protein maturationGO:00516041760.300
regulation of mast cell activationGO:0033003210.299
Mouse
thymic t cell selectionGO:0045061220.298
cell fate commitmentGO:00451652100.270
cellular protein complex assemblyGO:00436231160.267
t cell proliferationGO:00420981200.247
myeloid leukocyte differentiationGO:00025731190.246
morphogenesis of a branching epitheliumGO:00611381930.243
positive regulation of cellular component biogenesisGO:0044089940.242
leukocyte proliferationGO:00706611720.241
cellular response to growth factor stimulusGO:00713631970.235
regulation of wound healingGO:0061041400.234
Mouse
negative regulation of synapse assemblyGO:005196430.232
positive regulation of exocytosisGO:0045921200.226
Mouse
positive regulation of organelle organizationGO:00106381280.226
homeostasis of number of cellsGO:00488722100.224
regulation of leukocyte differentiationGO:19021051590.223
regulation of cellular ketone metabolic processGO:0010565660.219
regulation of inflammatory responseGO:00507271470.218
regulation of cytokine productionGO:00018172660.218
Mouse
peptidyl tyrosine phosphorylationGO:00181081430.215
regulation of leukocyte mediated immunityGO:00027031040.213
Mouse
cellular amino acid metabolic processGO:00065201030.213
regulation of coagulationGO:0050818310.211
Mouse
cell chemotaxisGO:0060326810.208
negative thymic t cell selectionGO:0045060120.207
gamma delta t cell differentiationGO:0042492110.207
Mouse
coagulationGO:0050817780.200
Mouse
regulation of toll like receptor 2 signaling pathwayGO:003413530.199
immune effector processGO:00022523210.194
Mouse
cell type specific apoptotic processGO:00972852680.193
regulation of actin filament polymerizationGO:0030833380.192
response to lipopolysaccharideGO:00324961280.192
regulation of blood coagulationGO:0030193280.192
Mouse
cellular amine metabolic processGO:0044106440.191
platelet activationGO:0030168400.188
Mouse
lymphocyte anergyGO:000224940.188
negative regulation of protein metabolic processGO:00512482820.184
platelet aggregationGO:0070527200.184
Mouse
cytokine productionGO:00018163190.177
Mouse
mast cell activation involved in immune responseGO:0002279200.177
Mouse
gland developmentGO:00487323300.174
embryonic placenta developmentGO:0001892980.173
isotype switching to igg isotypesGO:0048291100.171
regulation of actin polymerization or depolymerizationGO:0008064450.170
regulation of protein complex assemblyGO:0043254830.169
dna recombinationGO:0006310920.168
actin filament polymerizationGO:0030041440.165
b cell activationGO:00421131610.165
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.164
leukocyte degranulationGO:0043299270.162
Mouse
fc receptor mediated stimulatory signaling pathwayGO:000243140.161
positive regulation of mapk cascadeGO:00434101700.161
Mouse
negative regulation of cellular amino acid metabolic processGO:004576300.157
mitotic cell cycle processGO:19030471590.154
regulation of t cell differentiationGO:0045580830.152
positive regulation of lymphocyte proliferationGO:0050671700.152
regulation of antigen receptor mediated signaling pathwayGO:0050854290.151
cation homeostasisGO:00550802120.151
positive regulation of immune effector processGO:00026991070.148
Mouse
gamma delta t cell lineage commitmentGO:000236510.148
morphogenesis of a branching structureGO:00017632030.143
endodermal cell fate specificationGO:000171440.142
peptidyl amino acid modificationGO:00181933360.142
regulation of b cell differentiationGO:0045577230.141
Mouse
regulation of b cell activationGO:0050864810.139
Mouse
interleukin 8 secretionGO:007260630.138
positive regulation of podosome assemblyGO:007180330.138
regulation of toll like receptor 4 signaling pathwayGO:003414340.138
regulation of organelle organizationGO:00330432890.136
regulation of cellular amino acid metabolic processGO:000652150.135
response to molecule of bacterial originGO:00022371430.128
regulation of actin cytoskeleton organizationGO:0032956840.122
protein polymerizationGO:0051258570.121
natural killer cell inhibitory signaling pathwayGO:000276920.121
positive regulation of antigen receptor mediated signaling pathwayGO:005085790.120
positive regulation of cytokine productionGO:00018191740.120
Mouse
positive regulation of cellular amine metabolic processGO:003324050.119
adaptive immune responseGO:00022501550.117
regulation of inflammatory response to antigenic stimulusGO:0002861210.116
regulation of interferon gamma productionGO:0032649570.116
innate immune responseGO:00450871570.115
Mouse
regulation of intracellular transportGO:00323861590.115
Mouse
regulation of protein secretionGO:0050708820.113
Mouse
alpha beta t cell differentiationGO:0046632690.112
positive regulation of production of molecular mediator of immune responseGO:0002702450.112
leukocyte apoptotic processGO:0071887710.112
negative regulation of protein modification processGO:00314001630.111
protein processingGO:00164851630.111
defense response to virusGO:0051607680.111
labyrinthine layer developmentGO:0060711490.109
cell divisionGO:00513011200.109
regulation of phospholipase c activityGO:190027430.108
positive regulation of cytoskeleton organizationGO:0051495490.106
positive regulation of phospholipase c activityGO:001086320.105
interferon gamma productionGO:0032609670.105
immunoglobulin mediated immune responseGO:0016064690.105
positive t cell selectionGO:0043368230.104
inner cell mass cell proliferationGO:0001833150.103
endocytosisGO:00068971680.102
Mouse Fly
regulation of secretionGO:00510462740.102
Mouse
positive regulation of regulated secretory pathwayGO:1903307100.101
Mouse
gamma delta t cell activationGO:0046629130.100
Mouse
mast cell activationGO:0045576270.100
Mouse
regulation of establishment of protein localizationGO:00702011810.100
Mouse
cd4 positive cd25 positive alpha beta regulatory t cell differentiationGO:000236140.100
regulation of protein localizationGO:00328802310.099
Mouse
positive regulation of isotype switching to igg isotypesGO:004830470.098
activation of phospholipase c activityGO:000720220.096
regulation of leukocyte apoptotic processGO:2000106560.096
peptidyl tyrosine modificationGO:00182121450.094
metal ion homeostasisGO:00550651890.093
regulation of secretion by cellGO:19035302490.092
Mouse
regulation of peptidase activityGO:0052547960.092
alpha beta t cell proliferationGO:0046633210.091
t cell selectionGO:0045058340.090
regulation of interleukin 8 productionGO:003267730.089
positive regulation of protein complex assemblyGO:0031334450.089
mitotic cell cycleGO:00002781950.089
response to organonitrogen compoundGO:00102432460.088
positive regulation of gamma delta t cell differentiationGO:004558860.087
Mouse
membrane invaginationGO:0010324170.086
somatic diversification of immunoglobulinsGO:0016445430.086
lymphocyte proliferationGO:00466511640.086
defense response to other organismGO:00985421970.086
Mouse
regulation of membrane potentialGO:00423911920.085
regulation of calcium mediated signalingGO:0050848190.085
olfactory learningGO:000835520.084
leukocyte homeostasisGO:0001776790.084
regulation of lymphocyte differentiationGO:00456191070.084
germ cell developmentGO:00072811850.084
Fly
regulation of protein catabolic processGO:00421761080.084
cellular zinc ion homeostasisGO:000688290.083
negative regulation of apoptotic signaling pathwayGO:20012341040.083
regulation of production of molecular mediator of immune responseGO:0002700650.083
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.081
cellular homeostasisGO:00197252400.081
positive regulation of cytokine secretionGO:0050715410.081
Mouse
divalent inorganic cation homeostasisGO:00725071380.080
production of molecular mediator of immune responseGO:00024401030.080
protein localization to plasma membraneGO:0072659570.080
negative regulation of t cell activationGO:0050868650.079
regulation of platelet activationGO:0010543170.079
Mouse
positive regulation of leukocyte differentiationGO:1902107860.079
inflammatory responseGO:00069542440.078
Mouse
cellular ion homeostasisGO:00068731650.078
b cell receptor signaling pathwayGO:0050853200.078
Mouse
positive regulation of alpha beta t cell differentiationGO:0046638280.078
regulation of cellular amine metabolic processGO:0033238200.077
calcium ion homeostasisGO:00550741270.077
regulation of cytoskeleton organizationGO:00514931220.076
platelet degranulationGO:000257660.076
Mouse
regulation of protein kinase activityGO:00458592320.076
Mouse
developmental maturationGO:00217001930.075
regulation of map kinase activityGO:00434051200.075
Mouse
actin filament bundle assemblyGO:0051017400.075
positive regulation of cellular amino acid metabolic processGO:004576430.075
negative regulation of leukocyte proliferationGO:0070664460.075
organelle localizationGO:00516401790.074
Mouse
response to fibroblast growth factorGO:0071774470.074
cellular glucan metabolic processGO:0006073320.074
regulation of dna recombinationGO:0000018340.074
regulation of defense responseGO:00313472330.073
maintenance of locationGO:0051235890.073
t cell lineage commitmentGO:0002360130.073
negative regulation of intracellular signal transductionGO:19025321670.073
cellular response to organonitrogen compoundGO:00714171450.072
small gtpase mediated signal transductionGO:0007264970.071
positive regulation of regulatory t cell differentiationGO:004559140.071
negative regulation of lymphocyte activationGO:0051250910.070
positive regulation of phosphatidylinositol 3 kinase signalingGO:0014068200.070
positive regulation of programmed cell deathGO:00430682180.070
protein localization to membraneGO:00726571080.069
anatomical structure homeostasisGO:00602491450.069
Mouse
positive regulation of protein kinase activityGO:00458601440.069
Mouse
immune response regulating signaling pathwayGO:00027641250.068
positive regulation of t cell activationGO:00508701010.068
regulation of alpha beta t cell differentiationGO:0046637350.067
positive regulation of cell deathGO:00109422240.067
g protein coupled receptor signaling pathwayGO:00071862430.067
positive regulation of lymphocyte anergyGO:000291340.066
regulation of t cell proliferationGO:0042129920.065
extrinsic apoptotic signaling pathwayGO:00971911260.065
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.065
cytokine secretionGO:0050663720.065
Mouse
immune response inhibiting cell surface receptor signaling pathwayGO:000276730.064
cation transportGO:00068123990.064
Mouse
macromolecule catabolic processGO:00090572810.064
posttranscriptional regulation of gene expressionGO:00106081550.064
positive regulation of cell activationGO:00508671580.064
regulation of proteolysisGO:00301621640.063
positive regulation of cell projection organizationGO:0031346950.063
regulation of b cell mediated immunityGO:0002712370.062
regulation of endocytosisGO:0030100690.061
Mouse
regulation of lymphocyte mediated immunityGO:0002706840.061
tissue homeostasisGO:00018941150.061
Mouse
hematopoietic stem cell migrationGO:003570110.061
regulation of cellular component biogenesisGO:00440871810.061
positive regulation of actin filament polymerizationGO:0030838260.061
negative regulation of cellular protein metabolic processGO:00322692470.059
integrin mediated signaling pathwayGO:0007229270.059
Mouse
leukocyte activation involved in immune responseGO:00023661260.058
Mouse
positive regulation of b cell mediated immunityGO:0002714260.058
positive regulation of inflammatory responseGO:0050729470.058
exocrine system developmentGO:0035272450.058
regulation of interleukin 8 secretionGO:200048220.058
osteoclast differentiationGO:0030316620.058
cellular response to acid chemicalGO:0071229680.057
regulation of immunoglobulin mediated immune responseGO:0002889370.057
regulation of protein transportGO:00512231630.056
Mouse
lymphocyte apoptotic processGO:0070227540.056
cellularizationGO:000734910.056
leukocyte migrationGO:00509001240.056
cellular response to hormone stimulusGO:00328701500.055
forebrain developmentGO:00309003020.055
lymphocyte homeostasisGO:0002260640.055
positive regulation of adaptive immune responseGO:0002821610.054
single organismal cell cell adhesionGO:00163371310.054
Mouse
negative regulation of myeloid leukocyte differentiationGO:0002762200.054
microtubule based processGO:00070172360.054
leukocyte mediated immunityGO:00024431740.053
Mouse
regulation of alpha beta t cell proliferationGO:0046640180.053
positive regulation of cell migrationGO:00303351090.052
Zebrafish
regulation of kinase activityGO:00435492490.052
Mouse
protein catabolic processGO:00301632210.052
regulation of leukocyte degranulationGO:0043300200.052
Mouse
myeloid leukocyte mediated immunityGO:0002444420.051
Mouse
immunoglobulin productionGO:0002377730.051
fibrinolysisGO:004273030.051
regulation of lymphocyte apoptotic processGO:0070228410.051
t cell costimulationGO:0031295140.050
somatic cell dna recombinationGO:0016444510.050
positive regulation of cell developmentGO:00107202370.050
positive regulation of protein secretionGO:0050714520.050
Mouse
regulation of endopeptidase activityGO:0052548890.050
positive regulation of interleukin 2 biosynthetic processGO:004508680.050
interleukin 4 productionGO:0032633240.049
intracellular steroid hormone receptor signaling pathwayGO:0030518290.049
cellular lipid metabolic processGO:00442553230.049
Mouse
negative regulation of toll like receptor 2 signaling pathwayGO:003413630.049
regulation of canonical wnt signaling pathwayGO:0060828820.049
regulation of mast cell activation involved in immune responseGO:0033006170.049
Mouse
regulation of mast cell proliferationGO:007066640.048
positive regulation of interleukin 2 productionGO:0032743190.048
detection of molecule of bacterial originGO:003249020.048
positive regulation of phospholipase activityGO:001051830.048
placenta developmentGO:00018901400.048
regulation of homotypic cell cell adhesionGO:0034110130.048
Mouse
regulation of neuron differentiationGO:00456642810.048
b cell proliferationGO:0042100530.047
sequestering of calcium ionGO:0051208180.047
calcium mediated signalingGO:0019722460.047
plasma membrane organizationGO:0007009900.047
positive regulation of apoptotic signaling pathwayGO:2001235950.046
negative regulation of cellular component organizationGO:00511291940.046
defense response to bacteriumGO:00427421190.045
Mouse
regulation of vesicle mediated transportGO:00606271390.045
Mouse
muscle cell differentiationGO:00426922610.045
nuclear divisionGO:00002801580.044
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.044
negative regulation of interleukin 8 productionGO:003271710.044
cellular response to fibroblast growth factor stimulusGO:0044344470.044
neutrophil activationGO:004211990.044
Mouse
regulation of b cell proliferationGO:0030888390.044
regulation of hydrolase activityGO:00513362460.044
positive regulation of protein modification processGO:00314012990.044
Mouse
immune response inhibiting signal transductionGO:000276540.043
regulation of t cell mediated cytotoxicityGO:0001914180.043
neutrophil activation involved in immune responseGO:000228380.043
Mouse
microtubule cytoskeleton organizationGO:00002261570.043
zymogen activationGO:0031638410.043
regulation of cell cycle processGO:00105641600.043
myeloid cell homeostasisGO:00022621140.043
regulation of protein maturationGO:1903317960.042
cellular ketone metabolic processGO:0042180840.042
myeloid leukocyte activationGO:0002274830.042
Mouse
positive regulation of nucleotide metabolic processGO:00459811140.042
mast cell apoptotic processGO:003302450.041
regulation of b cell receptor signaling pathwayGO:005085590.041
regulation of interleukin 2 productionGO:0032663280.041
myeloid cell apoptotic processGO:0033028220.041
i kappab kinase nf kappab signalingGO:0007249850.040
positive regulation of leukocyte mediated immunityGO:0002705700.040
Mouse
regulation of mast cell degranulationGO:0043304160.039
Mouse
type b pancreatic cell proliferationGO:0044342100.039
canonical wnt signaling pathwayGO:00600701300.039
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.039
positive regulation of b cell activationGO:0050871490.039
Mouse
regulation of cysteine type endopeptidase activityGO:2000116650.039
regulation of wnt signaling pathwayGO:00301111230.038
monoamine transportGO:0015844330.038
Mouse
negative regulation of leukocyte differentiationGO:1902106510.038
cytokine mediated signaling pathwayGO:00192211150.037
regulation of anatomical structure sizeGO:00900661780.037
salivary gland developmentGO:0007431370.037
positive regulation of apoptotic processGO:00430652170.037
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.037
interleukin 2 productionGO:0032623330.037
zinc ion homeostasisGO:0055069100.037
negative regulation of cell activationGO:00508661110.036
regulation of activated t cell proliferationGO:0046006160.036
neuronal action potentialGO:0019228540.036
positive regulation of protein transportGO:0051222930.036
Mouse
regulation of cell shapeGO:0008360390.036
Fly
negative regulation of cellular amine metabolic processGO:003323910.036
negative regulation of phosphorylationGO:00423261660.036
positive regulation of protein phosphorylationGO:00019342420.035
Mouse
endomembrane system organizationGO:00102561470.035
regulation of b cell apoptotic processGO:0002902130.035
ras protein signal transductionGO:0007265770.035
lymphocyte activation involved in immune responseGO:0002285930.035
organelle fissionGO:00482851700.035
negative regulation of homeostatic processGO:0032845710.034
blood circulationGO:00080151950.034
cytosolic calcium ion homeostasisGO:0051480700.034
glycogen metabolic processGO:0005977320.034
regulation of apoptotic signaling pathwayGO:20012331970.034
b cell mediated immunityGO:0019724710.034
fc receptor mediated inhibitory signaling pathwayGO:000277410.034
cellular response to lipidGO:00713961450.033
response to reactive oxygen speciesGO:0000302560.033
positive regulation of canonical wnt signaling pathwayGO:0090263290.033
positive regulation of nervous system developmentGO:00519622210.033
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.033
interleukin 6 productionGO:0032635580.033
protein modification by small protein conjugation or removalGO:00706472070.033
regionalizationGO:00030023370.033
antigen processing and presentationGO:0019882470.032
positive regulation of leukocyte proliferationGO:0070665730.032
positive regulation of dna recombinationGO:0045911170.032
leukocyte chemotaxisGO:0030595690.032
positive regulation of interleukin 8 secretionGO:200048410.032
cellular metal ion homeostasisGO:00068751510.032
regulation of podosome assemblyGO:007180130.031
positive regulation of lymphocyte mediated immunityGO:0002708620.031
positive regulation of kinase activityGO:00336741550.031
Mouse
positive regulation of dendritic cell apoptotic processGO:200067030.031
regulation of phosphatidylinositol 3 kinase signalingGO:0014066300.031
negative regulation of protein maturationGO:1903318790.031
positive regulation of transferase activityGO:00513471670.031
Mouse
platelet derived growth factor receptor signaling pathwayGO:0048008320.031
alpha amino acid metabolic processGO:1901605590.030
protein modification by small protein conjugationGO:00324461870.030
intracellular receptor signaling pathwayGO:0030522740.030
interleukin 2 mediated signaling pathwayGO:003811020.030
negative regulation of growthGO:0045926990.030
regulation of nucleoside metabolic processGO:00091181300.030
cell junction organizationGO:0034330770.030
regulation of lipase activityGO:0060191150.030
hepatocyte growth factor receptor signaling pathwayGO:004801230.030
gliogenesisGO:00420631410.029
membrane organizationGO:00610242450.029
tolerance induction to self antigenGO:000251340.029
regulation of isotype switchingGO:0045191220.029
myotube differentiationGO:00149021050.029
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.029
rho protein signal transductionGO:0007266320.029
negative regulation of leukocyte mediated immunityGO:0002704290.029
positive regulation of wnt signaling pathwayGO:0030177450.029
toll like receptor 2 signaling pathwayGO:003413460.029
positive regulation of t cell costimulationGO:200052520.029
positive regulation of immunoglobulin mediated immune responseGO:0002891260.028
response to ethanolGO:0045471180.028
negative regulation of protein phosphorylationGO:00019331260.028
multicellular organismal signalingGO:0035637910.028
organic cyclic compound catabolic processGO:19013612950.028
regulation of phagocytosisGO:0050764330.028
Mouse
lysosome localizationGO:0032418200.028
Mouse
interleukin 8 productionGO:003263740.028
regulation of asymmetric cell divisionGO:000978640.028
cell activation involved in immune responseGO:00022631260.028
Mouse
nuclear transportGO:00511691390.028
serotonin secretion involved in inflammatory responseGO:000244240.028
Mouse
branching involved in mammary gland duct morphogenesisGO:0060444270.028
purine nucleoside triphosphate metabolic processGO:00091442260.028
learningGO:0007612980.028
skeletal muscle organ developmentGO:00605381630.028
transmission of nerve impulseGO:0019226760.028
labyrinthine layer morphogenesisGO:0060713210.027
male gamete generationGO:00482322850.027
positive regulation of defense responseGO:00313491240.027
positive regulation of actin filament bundle assemblyGO:0032233110.027
positive regulation of type iii hypersensitivityGO:000180530.027
erk1 and erk2 cascadeGO:0070371770.027
Mouse
cellular polysaccharide metabolic processGO:0044264380.027
detection of mechanical stimulus involved in sensory perception of painGO:005096640.027
negative regulation of phosphate metabolic processGO:00459361840.027
positive regulation of secretionGO:00510471300.027
Mouse
interleukin 27 mediated signaling pathwayGO:007010610.026
positive regulation of response to woundingGO:1903036660.026
female gamete generationGO:0007292740.026
Fly
cellular response to insulin stimulusGO:0032869780.026
engulfment of apoptotic cellGO:004365230.026
negative regulation of phosphorus metabolic processGO:00105631840.026
positive regulation of t cell proliferationGO:0042102520.026
sequestering of metal ionGO:0051238190.026
somatic diversification of immune receptorsGO:0002200530.026
chemotaxisGO:00069352470.026
regulation of calcium ion transport into cytosolGO:0010522310.026
regulation of cytoplasmic transportGO:19036491120.026
negative regulation of t cell mediated cytotoxicityGO:000191530.026
organonitrogen compound catabolic processGO:19015652640.026
regulation of cell migrationGO:00303342190.025
Zebrafish
multicellular organismal homeostasisGO:00488711640.025
Mouse
positive regulation of alpha beta t cell activationGO:0046635390.025
regulation of lymphocyte proliferationGO:00506701170.025
cellular calcium ion homeostasisGO:00068741190.025
regulation of protein serine threonine kinase activityGO:00719001570.025
Mouse
granulocyte migrationGO:0097530430.025
regulation of system processGO:00440572000.025
isotype switchingGO:0045190360.025
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathwayGO:001057930.025
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.025
negative regulation of t cell apoptotic processGO:0070233180.025
associative learningGO:0008306610.025
synaptic transmissionGO:00072683290.024
regulation of acute inflammatory responseGO:0002673270.024
positive regulation of alpha beta t cell proliferationGO:0046641120.024
phosphatidylinositol mediated signalingGO:0048015410.024
salivary gland morphogenesisGO:0007435330.024
wound healingGO:00420601570.024
Mouse
meiotic nuclear divisionGO:00071261150.024
neutrophil migrationGO:1990266370.024
serotonin production involved in inflammatory responseGO:000235140.024
Mouse
mast cell mediated immunityGO:0002448200.024
Mouse
positive regulation of interferon gamma productionGO:0032729390.024
myeloid cell differentiationGO:00300992330.024
regulation of transferase activityGO:00513382630.023
Mouse
energy derivation by oxidation of organic compoundsGO:0015980770.023
nucleoside phosphate metabolic processGO:00067533380.023
granulocyte chemotaxisGO:0071621390.023
regulation of peptidyl tyrosine phosphorylationGO:0050730930.023
Mouse
adherens junction organizationGO:0034332280.023
sensory perception of painGO:0019233470.023
positive regulation of interleukin 10 productionGO:0032733120.023
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.023
regulation of cell divisionGO:0051302760.023
cytoplasmic transportGO:00164822340.023
regulation of immunoglobulin productionGO:0002637420.023
cellular response to retinoic acidGO:0071300250.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.022
negative regulation of b cell activationGO:0050869270.022
regulation of synaptic growth at neuromuscular junctionGO:000858240.022
membrane depolarizationGO:0051899640.022
lymphocyte costimulationGO:0031294150.022
response to acid chemicalGO:00011011110.022
regulation of cellular catabolic processGO:00313292420.022
sensory perceptionGO:00076002450.021
negative regulation of leukocyte apoptotic processGO:2000107310.021
positive regulation of mast cell degranulationGO:0043306100.021
Mouse
positive regulation of acute inflammatory responseGO:0002675160.021

Zap70 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.341
disease of anatomical entityDOID:700.341
nervous system diseaseDOID:86300.060
hypersensitivity reaction diseaseDOID:006005600.042