IMP: Integrative Multi-species Prediction

Mus musculus

39 known processes

Pkdrej

polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly, sea urchin homolog)-like

Entrez: 18766
Ensembl: ENSMUSG00000052496
UniProtKB: F8VQF3

Process Predictions
Disease Predictions

Pkdrej biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cation transmembrane transport	GO:0098655	266	0.322	Mouse
transmembrane transport	GO:0055085	412	0.312	Mouse
ion transmembrane transport	GO:0034220	361	0.266	Mouse
g protein coupled receptor signaling pathway	GO:0007186	243	0.178	Mouse
cation transport	GO:0006812	399	0.163	Mouse
multicellular organismal signaling	GO:0035637	91	0.145
inorganic cation transmembrane transport	GO:0098662	207	0.137	Mouse
inorganic ion transmembrane transport	GO:0098660	234	0.136	Mouse
circulatory system process	GO:0003013	197	0.132
cellular amino acid metabolic process	GO:0006520	103	0.119
locomotory behavior	GO:0007626	195	0.118
regulation of ion transport	GO:0043269	215	0.112	Mouse
synaptic transmission	GO:0007268	329	0.108
action potential	GO:0001508	78	0.097
fertilization	GO:0009566	127	0.085
neuronal action potential	GO:0019228	54	0.079
blood circulation	GO:0008015	195	0.077
stem cell development	GO:0048864	219	0.075
regulation of ion transmembrane transport	GO:0034765	119	0.070	Mouse
b cell activation	GO:0042113	161	0.068
cellular chemical homeostasis	GO:0055082	215	0.068	Mouse
mesenchyme development	GO:0060485	152	0.067
transmission of nerve impulse	GO:0019226	76	0.065
regulation of membrane potential	GO:0042391	192	0.063
muscle system process	GO:0003012	141	0.062
stem cell differentiation	GO:0048863	268	0.062
regulation of cell cycle	GO:0051726	281	0.062	Mouse
activation of mapk activity involved in innate immune response	GO:0035419	2	0.062
potassium ion transmembrane transport	GO:0071805	43	0.059	Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.058
regulation of blood circulation	GO:1903522	93	0.055
sensory perception	GO:0007600	245	0.052	Mouse
germ cell development	GO:0007281	185	0.048
adult behavior	GO:0030534	135	0.048
habituation	GO:0046959	3	0.047
response to radiation	GO:0009314	165	0.047
dna metabolic process	GO:0006259	303	0.046
regulation of blood pressure	GO:0008217	93	0.046
male gamete generation	GO:0048232	285	0.045
amine metabolic process	GO:0009308	45	0.045
muscle tissue development	GO:0060537	308	0.045
sensory perception of mechanical stimulus	GO:0050954	107	0.043
regulation of secretion by cell	GO:1903530	249	0.042
ear morphogenesis	GO:0042471	118	0.041
tissue remodeling	GO:0048771	102	0.041
regionalization	GO:0003002	337	0.041	Mouse
regulation of action potential	GO:0098900	4	0.040
sensory organ morphogenesis	GO:0090596	242	0.040
macromolecule catabolic process	GO:0009057	281	0.039	Mouse
organonitrogen compound biosynthetic process	GO:1901566	192	0.039
anion transport	GO:0006820	177	0.038
positive regulation of phospholipase activity	GO:0010518	3	0.037
muscle contraction	GO:0006936	101	0.036
divalent inorganic cation transport	GO:0072511	178	0.036	Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.036
embryonic placenta development	GO:0001892	98	0.036	Mouse
regulation of circadian sleep wake cycle sleep	GO:0045187	3	0.036
regulation of transmembrane transport	GO:0034762	128	0.036	Mouse
regulation of lymphocyte activation	GO:0051249	240	0.036
renal system development	GO:0072001	225	0.036	Mouse
regulation of homeostatic process	GO:0032844	182	0.035	Mouse
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	55	0.035
neuropeptide signaling pathway	GO:0007218	19	0.035
organic hydroxy compound metabolic process	GO:1901615	203	0.034
myelination	GO:0042552	74	0.034
response to light stimulus	GO:0009416	135	0.034
positive regulation of lymphocyte activation	GO:0051251	140	0.034
ear development	GO:0043583	200	0.033
regulation of circadian sleep wake cycle	GO:0042749	3	0.033
divalent metal ion transport	GO:0070838	172	0.033	Mouse
cellular metal ion homeostasis	GO:0006875	151	0.033	Mouse
norepinephrine secretion	GO:0048243	2	0.033
protein catabolic process	GO:0030163	221	0.032	Mouse
ribose phosphate metabolic process	GO:0019693	291	0.032	Mouse
negative regulation of molecular function	GO:0044092	258	0.032	Mouse
mesenchymal cell differentiation	GO:0048762	107	0.032
multi multicellular organism process	GO:0044706	109	0.031	Worm
carboxylic acid transport	GO:0046942	100	0.031
positive regulation of homeostatic process	GO:0032846	64	0.031
adult locomotory behavior	GO:0008344	91	0.031
cellular modified amino acid metabolic process	GO:0006575	63	0.031
learning	GO:0007612	98	0.031
positive regulation of cellular amine metabolic process	GO:0033240	5	0.030
regulation of cellular amino acid metabolic process	GO:0006521	5	0.030
nuclear transport	GO:0051169	139	0.029	Mouse
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.029
negative regulation of cytokine production	GO:0001818	84	0.029
organophosphate biosynthetic process	GO:0090407	122	0.029
nucleoside phosphate biosynthetic process	GO:1901293	79	0.029
regulation of cellular amine metabolic process	GO:0033238	20	0.029
metal ion homeostasis	GO:0055065	189	0.028	Mouse
cellular ketone metabolic process	GO:0042180	84	0.028
macromolecule methylation	GO:0043414	120	0.028
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway	GO:0051482	4	0.028
regulation of cell activation	GO:0050865	289	0.028
cellular amine metabolic process	GO:0044106	44	0.028
cation homeostasis	GO:0055080	212	0.027	Mouse
regulation of metal ion transport	GO:0010959	106	0.027	Mouse
immune effector process	GO:0002252	321	0.027
norepinephrine transport	GO:0015874	2	0.027
cellular response to hormone stimulus	GO:0032870	150	0.027
b cell differentiation	GO:0030183	78	0.027
regulation of system process	GO:0044057	200	0.027
leukocyte differentiation	GO:0002521	342	0.026
detection of stimulus	GO:0051606	84	0.026	Mouse
mapk cascade	GO:0000165	281	0.026
regulation of systemic arterial blood pressure	GO:0003073	61	0.026
ensheathment of neurons	GO:0007272	76	0.026
embryonic organ morphogenesis	GO:0048562	276	0.026
axon ensheathment	GO:0008366	76	0.026
pirna metabolic process	GO:0034587	12	0.025
divalent inorganic cation homeostasis	GO:0072507	138	0.025	Mouse
conditioned taste aversion	GO:0001661	4	0.025
spermatogenesis	GO:0007283	284	0.025
multicellular organism growth	GO:0035264	161	0.025
blood vessel morphogenesis	GO:0048514	285	0.025
epithelial cell development	GO:0002064	159	0.025
male meiosis	GO:0007140	37	0.025
sensory perception of sound	GO:0007605	97	0.024
regulation of cellular ketone metabolic process	GO:0010565	66	0.024
protein modification by small protein conjugation or removal	GO:0070647	207	0.024
positive regulation of cell adhesion	GO:0045785	80	0.024
nucleobase containing small molecule metabolic process	GO:0055086	352	0.024	Mouse
regulation of purine nucleotide metabolic process	GO:1900542	169	0.024	Mouse
cellular ion homeostasis	GO:0006873	165	0.024	Mouse
leukocyte migration	GO:0050900	124	0.024
glial cell development	GO:0021782	54	0.024
prevention of polyspermy	GO:0060468	4	0.024
nitrogen compound transport	GO:0071705	271	0.023
single organismal cell cell adhesion	GO:0016337	131	0.023	Mouse
cellular response to lipid	GO:0071396	145	0.023
bone remodeling	GO:0046849	53	0.023
regulation of hormone levels	GO:0010817	211	0.023
cyclic nucleotide metabolic process	GO:0009187	59	0.023	Mouse
protein targeting	GO:0006605	143	0.023	Mouse
mitotic cell cycle	GO:0000278	195	0.023	Mouse
regulation of leukocyte differentiation	GO:1902105	159	0.023
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.022
apoptotic signaling pathway	GO:0097190	306	0.022
organic cyclic compound catabolic process	GO:1901361	295	0.022
bone resorption	GO:0045453	38	0.022
protein localization to organelle	GO:0033365	185	0.022	Mouse
heart process	GO:0003015	94	0.022
response to organic cyclic compound	GO:0014070	198	0.022
epithelial tube morphogenesis	GO:0060562	303	0.022	Mouse
regulation of protein localization	GO:0032880	231	0.022	Mouse
negative regulation of protein transport	GO:0051224	46	0.022	Mouse
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.021
regulation of cation channel activity	GO:2001257	22	0.021	Mouse
operant conditioning	GO:0035106	2	0.021
digestive tract morphogenesis	GO:0048546	147	0.021
cellular homeostasis	GO:0019725	240	0.021	Mouse
positive regulation of protein modification process	GO:0031401	299	0.021
regulation of eosinophil migration	GO:2000416	2	0.021
regulation of anatomical structure size	GO:0090066	178	0.021
cellular macromolecule catabolic process	GO:0044265	206	0.021	Mouse
cognition	GO:0050890	149	0.021
regulation of camp metabolic process	GO:0030814	30	0.021	Mouse
posttranscriptional regulation of gene expression	GO:0010608	155	0.021
positive regulation of cell development	GO:0010720	237	0.020
lymphocyte differentiation	GO:0030098	242	0.020
response to growth factor	GO:0070848	198	0.020
organic acid transport	GO:0015849	101	0.020
urogenital system development	GO:0001655	261	0.020	Mouse
gliogenesis	GO:0042063	141	0.020
negative regulation of phosphate metabolic process	GO:0045936	184	0.020
regulation of cytokine production	GO:0001817	266	0.020
organic anion transport	GO:0015711	137	0.020
fibronectin dependent thymocyte migration	GO:0072681	1	0.020
single fertilization	GO:0007338	82	0.020
oocyte axis specification	GO:0007309	2	0.020
forebrain development	GO:0030900	302	0.020
negative regulation of growth	GO:0045926	99	0.020
carbohydrate metabolic process	GO:0005975	230	0.019
cellular potassium ion transport	GO:0071804	43	0.019	Mouse
regulation of heart contraction	GO:0008016	77	0.019
response to acid chemical	GO:0001101	111	0.019
cytosolic calcium ion homeostasis	GO:0051480	70	0.019	Mouse
positive regulation of protein phosphorylation	GO:0001934	242	0.019
rhythmic process	GO:0048511	174	0.019
cell division	GO:0051301	120	0.019
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.019	Mouse
striated muscle contraction	GO:0006941	45	0.019
forebrain neuron differentiation	GO:0021879	52	0.019
respiratory tube development	GO:0030323	167	0.019
camp biosynthetic process	GO:0006171	31	0.019
spermatid differentiation	GO:0048515	115	0.019
nucleoside phosphate metabolic process	GO:0006753	338	0.019	Mouse
regulation of purine nucleotide biosynthetic process	GO:1900371	34	0.019
calcium ion transmembrane transport	GO:0070588	85	0.018	Mouse
carbohydrate transport	GO:0008643	62	0.018
regulation of organelle organization	GO:0033043	289	0.018	Mouse
central nervous system neuron differentiation	GO:0021953	162	0.018
positive regulation of cell activation	GO:0050867	158	0.018
intracellular mrna localization	GO:0008298	4	0.018
nucleotide biosynthetic process	GO:0009165	78	0.018
mesodermal cell migration	GO:0008078	4	0.018
regulation of mitotic cell cycle	GO:0007346	126	0.018	Mouse
phenol containing compound metabolic process	GO:0018958	60	0.018
positive regulation of cellular catabolic process	GO:0031331	148	0.018
renal sodium excretion	GO:0035812	3	0.018
regulation of tissue remodeling	GO:0034103	38	0.017
ossification	GO:0001503	216	0.017
peptidyl amino acid modification	GO:0018193	336	0.017	Mouse
rna processing	GO:0006396	105	0.017
establishment of protein localization to organelle	GO:0072594	118	0.017	Mouse
carbohydrate derivative biosynthetic process	GO:1901137	183	0.017
positive regulation of hydrolase activity	GO:0051345	148	0.017
regulation of acetylcholine secretion neurotransmission	GO:0014056	2	0.017
purine nucleotide metabolic process	GO:0006163	302	0.017	Mouse
protein modification by small protein conjugation	GO:0032446	187	0.017
cellular response to growth factor stimulus	GO:0071363	197	0.017
cell maturation	GO:0048469	127	0.017
spleen development	GO:0048536	39	0.017
sa node cell action potential	GO:0086015	4	0.017
asymmetric stem cell division	GO:0098722	3	0.017
renal system process	GO:0003014	48	0.017
activation of transmembrane receptor protein tyrosine kinase activity	GO:0007171	3	0.017
purine nucleotide biosynthetic process	GO:0006164	65	0.016
phospholipase c activating g protein coupled receptor signaling pathway	GO:0007200	26	0.016
regulation of peptide secretion	GO:0002791	77	0.016
positive regulation of membrane protein ectodomain proteolysis	GO:0051044	3	0.016
neuron migration	GO:0001764	122	0.016
organic hydroxy compound transport	GO:0015850	93	0.016
peptide transport	GO:0015833	133	0.016
negative regulation of cellular amine metabolic process	GO:0033239	1	0.016
regulation of membrane protein ectodomain proteolysis	GO:0051043	3	0.016
regulation of cell migration	GO:0030334	219	0.016
mrna metabolic process	GO:0016071	84	0.016
negative regulation of phosphorus metabolic process	GO:0010563	184	0.016
regulation of establishment of protein localization	GO:0070201	181	0.016	Mouse
cyclic nucleotide biosynthetic process	GO:0009190	44	0.016
response to extracellular stimulus	GO:0009991	127	0.016
positive regulation of transferase activity	GO:0051347	167	0.016
positive regulation of cell cycle	GO:0045787	92	0.016
lateral geniculate nucleus development	GO:0021771	1	0.016
regulation of proteolysis	GO:0030162	164	0.016	Mouse
chromatin organization	GO:0006325	206	0.016
cellular carbohydrate metabolic process	GO:0044262	119	0.016
activation of adenylate cyclase activity	GO:0007190	4	0.016
sodium ion transport	GO:0006814	73	0.016
response to nutrient levels	GO:0031667	109	0.016
protein import into nucleus	GO:0006606	95	0.016	Mouse
positive regulation of catecholamine secretion	GO:0033605	2	0.016
amino acid transport	GO:0006865	61	0.016
mammary placode formation	GO:0060596	4	0.016
regulation of cellular component biogenesis	GO:0044087	181	0.016
microtubule based process	GO:0007017	236	0.015	Mouse
wound healing	GO:0042060	157	0.015
t cell activation	GO:0042110	289	0.015
positive regulation of nucleotide biosynthetic process	GO:0030810	26	0.015
methylation	GO:0032259	134	0.015
protein secretion	GO:0009306	111	0.015
visual learning	GO:0008542	44	0.015
regulation of cell adhesion	GO:0030155	154	0.015	Mouse
smooth muscle contraction	GO:0006939	44	0.015
acid secretion	GO:0046717	33	0.015
cellular protein complex assembly	GO:0043623	116	0.015
peptidyl tyrosine modification	GO:0018212	145	0.015
camera type eye development	GO:0043010	266	0.015
inorganic anion transport	GO:0015698	43	0.015
cytoplasmic transport	GO:0016482	234	0.015	Mouse
pma inducible membrane protein ectodomain proteolysis	GO:0051088	1	0.015
regulation of secretion	GO:0051046	274	0.015
sa node cell to atrial cardiac muscle cell signalling	GO:0086018	4	0.015
camp metabolic process	GO:0046058	40	0.015	Mouse
regulation of cell motility	GO:2000145	236	0.015
binding of sperm to zona pellucida	GO:0007339	34	0.015
cell cell junction organization	GO:0045216	72	0.015
liver development	GO:0001889	66	0.015	Mouse
regulation of lipid metabolic process	GO:0019216	118	0.015
development of primary sexual characteristics	GO:0045137	143	0.015
membrane organization	GO:0061024	245	0.015
negative regulation of mitotic cell cycle	GO:0045930	58	0.014
positive regulation of secondary heart field cardioblast proliferation	GO:0072513	4	0.014
positive regulation of innate immune response	GO:0045089	80	0.014
gene silencing	GO:0016458	38	0.014
adenylate cyclase activating g protein coupled receptor signaling pathway	GO:0007189	30	0.014
spermatid development	GO:0007286	108	0.014
insulin secretion	GO:0030073	89	0.014
glial cell differentiation	GO:0010001	131	0.014
cellular nitrogen compound catabolic process	GO:0044270	280	0.014
oocyte construction	GO:0007308	2	0.014
modification dependent protein catabolic process	GO:0019941	133	0.014
rna splicing	GO:0008380	54	0.014
mesoderm development	GO:0007498	100	0.014
regulation of calcium ion transport	GO:0051924	69	0.014	Mouse
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.014
negative regulation of cellular protein metabolic process	GO:0032269	247	0.014
inflammatory response	GO:0006954	244	0.014
negative regulation of response to wounding	GO:1903035	77	0.014
hexose transport	GO:0008645	56	0.014
visual behavior	GO:0007632	45	0.014
embryonic limb morphogenesis	GO:0030326	126	0.014
negative regulation of cell proliferation	GO:0008285	296	0.014
connective tissue development	GO:0061448	179	0.014	Mouse
regulation of t cell activation	GO:0050863	170	0.014
learning or memory	GO:0007611	148	0.014
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.014
regulation of cyclic nucleotide biosynthetic process	GO:0030802	31	0.014
microtubule cytoskeleton organization	GO:0000226	157	0.014	Mouse
heart contraction	GO:0060047	93	0.014
positive regulation of thymocyte migration	GO:2000412	2	0.014
negative regulation of nervous system development	GO:0051961	156	0.014
ribonucleotide metabolic process	GO:0009259	291	0.014	Mouse
ubiquitin dependent protein catabolic process	GO:0006511	129	0.014
paramesonephric duct development	GO:0061205	3	0.014
circadian rhythm	GO:0007623	114	0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	61	0.013
immune response regulating signaling pathway	GO:0002764	125	0.013
positive regulation of organelle organization	GO:0010638	128	0.013
regulation of peptide hormone secretion	GO:0090276	75	0.013
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.013
negative regulation of cellular component organization	GO:0051129	194	0.013
mitotic cell cycle process	GO:1903047	159	0.013	Mouse
purine ribonucleotide biosynthetic process	GO:0009152	59	0.013
bmp signaling pathway	GO:0030509	93	0.013
cardiac ventricle development	GO:0003231	83	0.013
modification dependent macromolecule catabolic process	GO:0043632	133	0.013
sperm egg recognition	GO:0035036	37	0.013
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	43	0.013
visceral motor neuron differentiation	GO:0021524	3	0.013
regulation of cyclic nucleotide metabolic process	GO:0030799	40	0.013	Mouse
organelle fission	GO:0048285	170	0.013
regulation of cell cycle process	GO:0010564	160	0.013	Mouse
negative regulation of cell cycle	GO:0045786	123	0.013	Mouse
extracellular matrix dependent thymocyte migration	GO:0072680	1	0.013
positive regulation of eosinophil migration	GO:2000418	2	0.013
chemotaxis	GO:0006935	247	0.013
gene silencing by rna	GO:0031047	19	0.013
cardiac septum morphogenesis	GO:0060411	46	0.013
regulation of calcium ion transmembrane transport	GO:1903169	20	0.013	Mouse
nucleocytoplasmic transport	GO:0006913	139	0.013	Mouse
regulation of response to wounding	GO:1903034	189	0.013
cellular lipid metabolic process	GO:0044255	323	0.013
rna interference	GO:0016246	2	0.013
respiratory gaseous exchange	GO:0007585	43	0.013
his purkinje system development	GO:0003164	4	0.013
erk1 and erk2 cascade	GO:0070371	77	0.012
negative regulation of protein modification process	GO:0031400	163	0.012
positive regulation of tumor necrosis factor ligand superfamily member 11 production	GO:2000309	1	0.012
positive regulation of kinase activity	GO:0033674	155	0.012
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.012
regulation of serotonin secretion	GO:0014062	3	0.012
g protein coupled receptor internalization	GO:0002031	3	0.012
adult walking behavior	GO:0007628	41	0.012
positive regulation of cell death	GO:0010942	224	0.012
regulation of lyase activity	GO:0051339	13	0.012
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.012
homeostasis of number of cells	GO:0048872	210	0.012
neuron neuron synaptic transmission	GO:0007270	69	0.012
negative regulation of hormone metabolic process	GO:0032351	4	0.012
mesenchymal cell development	GO:0014031	93	0.012
regulation of renal sodium excretion	GO:0035813	3	0.012
purine containing compound metabolic process	GO:0072521	311	0.012	Mouse
cell differentiation in spinal cord	GO:0021515	53	0.012
angiogenesis	GO:0001525	201	0.012
response to transforming growth factor beta	GO:0071559	88	0.012
skeletal muscle cell differentiation	GO:0035914	66	0.012
acetylcholine transport	GO:0015870	2	0.012
glucose import	GO:0046323	32	0.012
nuclear import	GO:0051170	95	0.012	Mouse
catecholamine transport	GO:0051937	21	0.012
response to steroid hormone	GO:0048545	56	0.012
vascular process in circulatory system	GO:0003018	62	0.012
sperm motility	GO:0030317	47	0.012
axonogenesis	GO:0007409	274	0.012
aromatic compound catabolic process	GO:0019439	286	0.012
regulation of multi organism process	GO:0043900	111	0.012
regulation of mesenchymal cell proliferation involved in ureter development	GO:0072199	3	0.012
positive regulation of nucleotide metabolic process	GO:0045981	114	0.012
immune response activating signal transduction	GO:0002757	116	0.012
thymocyte migration	GO:0072679	2	0.012
detection of abiotic stimulus	GO:0009582	60	0.012	Mouse
mrna processing	GO:0006397	63	0.012
telencephalon cell migration	GO:0022029	55	0.012
t cell differentiation	GO:0030217	174	0.012
skeletal system development	GO:0001501	356	0.012	Mouse
histamine induced gastric acid secretion	GO:0001697	1	0.012
ribose phosphate biosynthetic process	GO:0046390	59	0.012
cyclic purine nucleotide metabolic process	GO:0052652	43	0.011
negative regulation of cell development	GO:0010721	169	0.011
regulation of nucleotide biosynthetic process	GO:0030808	34	0.011
reactive oxygen species metabolic process	GO:0072593	84	0.011
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.011
dna methylation involved in gamete generation	GO:0043046	15	0.011
interferon gamma production	GO:0032609	67	0.011
intracellular protein transport	GO:0006886	204	0.011	Mouse
toxin transport	GO:1901998	38	0.011
regulation of mrna metabolic process	GO:1903311	43	0.011
regulation of tube size	GO:0035150	57	0.011
somatic cell dna recombination	GO:0016444	51	0.011
monosaccharide transport	GO:0015749	58	0.011
oocyte anterior posterior axis specification	GO:0007314	2	0.011
positive regulation of secretion	GO:0051047	130	0.011
regulation of lymphocyte mediated immunity	GO:0002706	84	0.011
bundle of his development	GO:0003166	4	0.011
single organism cell adhesion	GO:0098602	156	0.011	Mouse
regulation of cyclase activity	GO:0031279	13	0.011
positive regulation of nervous system development	GO:0051962	221	0.011
cell adhesion	GO:0007155	329	0.011	Mouse
av node cell to bundle of his cell communication	GO:0086067	2	0.011
synapse organization	GO:0050808	125	0.011
ribonucleotide biosynthetic process	GO:0009260	59	0.011
calcium ion transport	GO:0006816	159	0.011	Mouse
regulation of protein transport	GO:0051223	163	0.011	Mouse
positive regulation of protein transport	GO:0051222	93	0.011
heart morphogenesis	GO:0003007	178	0.011
negative regulation of protein metabolic process	GO:0051248	282	0.011
negative regulation of protein phosphorylation	GO:0001933	126	0.011
corticotropin releasing hormone secretion	GO:0043396	2	0.011
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.011
positive regulation of leukocyte differentiation	GO:1902107	86	0.011
regulation of tumor necrosis factor ligand superfamily member 11 production	GO:2000307	1	0.011
positive regulation of fibronectin dependent thymocyte migration	GO:2000415	1	0.011
purine ribonucleotide metabolic process	GO:0009150	290	0.011	Mouse
meiotic cell cycle	GO:0051321	122	0.011
regulation of defense response	GO:0031347	233	0.011
histone modification	GO:0016570	159	0.011
purine containing compound biosynthetic process	GO:0072522	70	0.011
his purkinje system cell differentiation	GO:0060932	2	0.011
positive regulation of lymphocyte proliferation	GO:0050671	70	0.011
regulation of muscle system process	GO:0090257	80	0.011
cholesterol homeostasis	GO:0042632	44	0.011
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.010
regulation of neurotransmitter levels	GO:0001505	87	0.010
regulation of renin secretion into blood stream	GO:1900133	4	0.010
dephosphorylation	GO:0016311	129	0.010
regulation of nucleocytoplasmic transport	GO:0046822	73	0.010	Mouse
regulation of bmp signaling pathway	GO:0030510	60	0.010
second messenger mediated signaling	GO:0019932	73	0.010
lung development	GO:0030324	164	0.010
cytokine production	GO:0001816	319	0.010
regulation of mrna processing	GO:0050684	41	0.010
glycerolipid metabolic process	GO:0046486	122	0.010
regulation of leukocyte proliferation	GO:0070663	121	0.010
cochlea development	GO:0090102	35	0.010
cell substrate adhesion	GO:0031589	130	0.010
paraxial mesodermal cell differentiation	GO:0048342	2	0.010
peptide hormone secretion	GO:0030072	109	0.010
cell cell recognition	GO:0009988	44	0.010
protein kinase c activating g protein coupled receptor signaling pathway	GO:0007205	4	0.010
negative regulation of hormone biosynthetic process	GO:0032353	4	0.010
regulation of intracellular transport	GO:0032386	159	0.010	Mouse
myeloid cell differentiation	GO:0030099	233	0.010
heterocycle catabolic process	GO:0046700	280	0.010
cardiac muscle cell contraction	GO:0086003	7	0.010
positive regulation of apoptotic process	GO:0043065	217	0.010

Pkdrej disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.015
disease of anatomical entity	DOID:7	0.015
musculoskeletal system disease	DOID:17	0.011

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