Mus musculus

191 known processes

Irf3

interferon regulatory factor 3

(Aliases: IRF-3,MGC91046,C920001K05Rik)

Irf3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular ketone metabolic processGO:0042180840.139
regulation of cellular ketone metabolic processGO:0010565660.068
amine metabolic processGO:0009308450.055
regulation of lymphocyte activationGO:00512492400.052
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.049
cellular amino acid metabolic processGO:00065201030.046
dna metabolic processGO:00062593030.046
regulation of cellular amino acid metabolic processGO:000652150.043
immune effector processGO:00022523210.042
regulation of hydrolase activityGO:00513362460.042
regulation of mapk cascadeGO:00434082480.041
cellular nitrogen compound catabolic processGO:00442702800.040
modification dependent macromolecule catabolic processGO:00436321330.040
cellular amine metabolic processGO:0044106440.040
regulation of cell activationGO:00508652890.038
Mouse
negative regulation of immune system processGO:00026832090.038
organic cyclic compound catabolic processGO:19013612950.036
regulation of cellular amine metabolic processGO:0033238200.036
aromatic compound catabolic processGO:00194392860.036
positive regulation of hydrolase activityGO:00513451480.034
mapk cascadeGO:00001652810.034
transmembrane transportGO:00550854120.033
cellular ion homeostasisGO:00068731650.033
protein localization to nucleusGO:00345041210.032
cytokine productionGO:00018163190.031
cation homeostasisGO:00550802120.031
cell type specific apoptotic processGO:00972852680.031
cellular chemical homeostasisGO:00550822150.031
cation transportGO:00068123990.030
regulation of secretion by cellGO:19035302490.030
regulation of membrane potentialGO:00423911920.030
positive regulation of cellular amine metabolic processGO:003324050.029
glycosyl compound metabolic processGO:19016572460.028
regulation of transferase activityGO:00513382630.028
innate immune responseGO:00450871570.027
immune response regulating signaling pathwayGO:00027641250.027
Mouse
cell adhesionGO:00071553290.026
myeloid cell differentiationGO:00300992330.026
Mouse
skin developmentGO:00435882200.026
Mouse
cellular macromolecule catabolic processGO:00442652060.026
regulation of defense responseGO:00313472330.025
metal ion homeostasisGO:00550651890.024
protein localization to organelleGO:00333651850.024
ras protein signal transductionGO:0007265770.024
purine ribonucleoside metabolic processGO:00461282410.023
glycosyl compound catabolic processGO:19016582060.023
protein maturationGO:00516041760.023
macromolecule catabolic processGO:00090572810.023
peptidyl amino acid modificationGO:00181933360.023
Mouse
negative regulation of defense responseGO:0031348770.023
leukocyte differentiationGO:00025213420.023
Mouse
small gtpase mediated signal transductionGO:0007264970.022
neuron deathGO:00709971540.022
nucleoside catabolic processGO:00091642060.022
regulation of cell cycleGO:00517262810.022
negative regulation of cell developmentGO:00107211690.022
regulation of kinase activityGO:00435492490.022
organophosphate catabolic processGO:00464342320.022
heterocycle catabolic processGO:00467002800.022
ribose phosphate metabolic processGO:00196932910.022
ribonucleotide metabolic processGO:00092592910.021
purine nucleoside metabolic processGO:00422782410.021
cellular lipid metabolic processGO:00442553230.021
purine containing compound metabolic processGO:00725213110.020
proteolysis involved in cellular protein catabolic processGO:00516031470.020
nucleobase containing small molecule metabolic processGO:00550863520.020
positive regulation of mapk cascadeGO:00434101700.020
cellular metal ion homeostasisGO:00068751510.020
positive regulation of apoptotic processGO:00430652170.020
compound eye developmentGO:004874910.020
divalent inorganic cation transportGO:00725111780.020
apoptotic signaling pathwayGO:00971903060.020
purine ribonucleotide catabolic processGO:00091542080.019
nucleotide catabolic processGO:00091662170.019
ribonucleoside metabolic processGO:00091192450.019
regulation of reactive oxygen species metabolic processGO:2000377400.019
regulation of bindingGO:00510981110.019
Mouse
nucleoside phosphate metabolic processGO:00067533380.019
proteasomal protein catabolic processGO:0010498980.019
cellular divalent inorganic cation homeostasisGO:00725031270.019
cytoplasmic transportGO:00164822340.019
ribonucleoside triphosphate metabolic processGO:00091992200.019
regulation of cellular response to stressGO:00801351590.019
nucleic acid phosphodiester bond hydrolysisGO:0090305490.018
positive regulation of protein modification processGO:00314012990.018
nucleoside phosphate catabolic processGO:19012922220.018
reactive nitrogen species metabolic processGO:200105700.018
striated muscle tissue developmentGO:00147062930.018
purine nucleotide metabolic processGO:00061633020.018
inflammatory responseGO:00069542440.018
positive regulation of cell deathGO:00109422240.018
extrinsic apoptotic signaling pathwayGO:00971911260.018
nitrogen compound transportGO:00717052710.018
purine nucleotide catabolic processGO:00061952110.018
maintenance of locationGO:0051235890.017
defense response to other organismGO:00985421970.017
cellular homeostasisGO:00197252400.017
reactive oxygen species metabolic processGO:0072593840.017
purine nucleoside triphosphate metabolic processGO:00091442260.017
nucleocytoplasmic transportGO:00069131390.017
inorganic cation transmembrane transportGO:00986622070.017
blood vessel morphogenesisGO:00485142850.017
organonitrogen compound catabolic processGO:19015652640.017
positive regulation of nucleoside metabolic processGO:0045979910.017
regulation of body fluid levelsGO:00508781620.017
negative regulation of protein metabolic processGO:00512482820.017
glycoprotein biosynthetic processGO:0009101890.017
positive regulation of programmed cell deathGO:00430682180.017
activation of immune responseGO:00022531380.017
Mouse
chromatin organizationGO:00063252060.017
Mouse
muscle tissue developmentGO:00605373080.016
carbohydrate derivative catabolic processGO:19011362310.016
protein importGO:00170381010.016
histone modificationGO:00165701590.016
Mouse
regulation of cytokine productionGO:00018172660.016
response to radiationGO:00093141650.016
stem cell differentiationGO:00488632680.016
negative regulation of cellular amine metabolic processGO:003323910.016
ribonucleotide catabolic processGO:00092612080.016
protein targetingGO:00066051430.016
positive regulation of transferase activityGO:00513471670.016
gland developmentGO:00487323300.016
Mouse
divalent inorganic cation homeostasisGO:00725071380.016
negative regulation of cellular component organizationGO:00511291940.016
nucleoside triphosphate metabolic processGO:00091412300.016
regulation of organelle organizationGO:00330432890.016
lymphocyte differentiationGO:00300982420.016
Mouse
regulation of leukocyte differentiationGO:19021051590.016
Mouse
purine nucleoside catabolic processGO:00061522050.015
actin filament organizationGO:00070151130.015
nuclear importGO:0051170950.015
intracellular protein transportGO:00068862040.015
regulation of nucleotide metabolic processGO:00061401690.015
negative regulation of intracellular signal transductionGO:19025321670.015
regulation of homeostatic processGO:00328441820.015
forebrain developmentGO:00309003020.015
glucose homeostasisGO:00425931280.015
ion transmembrane transportGO:00342203610.015
ribonucleoside triphosphate catabolic processGO:00092031990.015
regulation of myeloid cell differentiationGO:0045637960.015
negative regulation of cell proliferationGO:00082852960.015
Mouse
carbohydrate derivative biosynthetic processGO:19011371830.015
negative regulation of apoptotic signaling pathwayGO:20012341040.015
immune response activating signal transductionGO:00027571160.015
Mouse
t cell activationGO:00421102890.015
Mouse
regulation of reactive oxygen species biosynthetic processGO:190342620.015
regionalizationGO:00030023370.015
purine nucleoside triphosphate catabolic processGO:00091462030.015
lymphocyte mediated immunityGO:00024491390.015
Mouse
action potentialGO:0001508780.015
negative regulation of molecular functionGO:00440922580.014
response to light stimulusGO:00094161350.014
regulation of protein localizationGO:00328802310.014
muscle cell differentiationGO:00426922610.014
protein autophosphorylationGO:0046777610.014
nucleoside triphosphate catabolic processGO:00091432050.014
digestive system developmentGO:00551232000.014
positive regulation of protein kinase activityGO:00458601440.014
positive regulation of actin nucleationGO:005112730.014
cation transmembrane transportGO:00986552660.014
peptide transportGO:00158331330.014
mitotic cell cycle processGO:19030471590.014
negative regulation of cellular amino acid metabolic processGO:004576300.014
protein localization to peroxisomeGO:007266240.013
positive regulation of protein transportGO:0051222930.013
regulation of cysteine type endopeptidase activityGO:2000116650.013
glycerolipid metabolic processGO:00464861220.013
regulation of ral gtpase activityGO:003231540.013
nucleoside metabolic processGO:00091162460.013
purine ribonucleotide metabolic processGO:00091502900.013
regulation of map kinase activityGO:00434051200.013
skeletal muscle organ developmentGO:00605381630.013
viral gene expressionGO:001908030.013
membrane organizationGO:00610242450.013
neuron apoptotic processGO:00514021420.013
rna processingGO:00063961050.013
nuclear transportGO:00511691390.013
purine ribonucleoside catabolic processGO:00461302050.013
regulation of feeding behaviorGO:006025930.013
regulation of sequence specific dna binding transcription factor activityGO:00510901060.013
positive regulation of cell activationGO:00508671580.013
negative regulation of immune effector processGO:0002698550.012
calcium ion homeostasisGO:00550741270.012
inorganic ion transmembrane transportGO:00986602340.012
establishment of protein localization to organelleGO:00725941180.012
protein processingGO:00164851630.012
sterol homeostasisGO:0055092450.012
glycoprotein metabolic processGO:00091001160.012
telencephalon developmentGO:00215371860.012
lipid homeostasisGO:0055088630.012
cellular response to lipidGO:00713961450.012
cellular response to biotic stimulusGO:0071216920.012
camera type eye developmentGO:00430102660.012
monocarboxylic acid metabolic processGO:00327871910.012
digestive tract developmentGO:00485651900.012
cilium morphogenesisGO:00602711020.012
i kappab kinase nf kappab signalingGO:0007249850.012
nucleotide metabolic processGO:00091173320.012
wnt signaling pathwayGO:00160551880.012
peptidyl tyrosine phosphorylationGO:00181081430.012
spermatogenesisGO:00072832840.012
actin cytoskeleton organizationGO:00300362200.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.012
activation of mapk activityGO:0000187590.012
response to lipopolysaccharideGO:00324961280.012
multicellular organism growthGO:00352641610.012
mitochondrion organizationGO:00070051340.012
carbohydrate homeostasisGO:00335001280.012
gtp metabolic processGO:00460391440.011
lateral inhibitionGO:004633110.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
Mouse
cellular protein catabolic processGO:00442571550.011
hematopoietic progenitor cell differentiationGO:00022441430.011
sequestering of metal ionGO:0051238190.011
adult behaviorGO:00305341350.011
regulation of cellular component biogenesisGO:00440871810.011
Mouse
mitotic cytokinesisGO:000028140.011
protein ubiquitinationGO:00165671710.011
defense response to bacteriumGO:00427421190.011
Mouse
asymmetric stem cell divisionGO:009872230.011
macromolecule glycosylationGO:0043413550.011
regulation of t cell activationGO:00508631700.011
Mouse
multicellular organismal homeostasisGO:00488711640.011
interleukin 8 productionGO:003263740.011
methylationGO:00322591340.011
Mouse
regulation of secretionGO:00510462740.011
response to molecule of bacterial originGO:00022371430.011
negative regulation of cellular protein metabolic processGO:00322692470.011
regulation of neuron projection developmentGO:00109751690.011
regulation of neuron apoptotic processGO:00435231220.011
response to acid chemicalGO:00011011110.011
regulation of adaptive immune responseGO:0002819900.011
regulation of inflammatory responseGO:00507271470.011
positive regulation of cell developmentGO:00107202370.011
posttranscriptional regulation of gene expressionGO:00106081550.011
positive regulation of interleukin 8 productionGO:003275720.011
protein glycosylationGO:0006486550.011
cellular calcium ion homeostasisGO:00068741190.011
negative regulation of multi organism processGO:0043901680.011
guanosine containing compound catabolic processGO:19010691440.011
homeostasis of number of cellsGO:00488722100.011
t cell proliferationGO:00420981200.011
Mouse
mrna metabolic processGO:0016071840.011
protein polymerizationGO:0051258570.011
negative regulation of phosphorus metabolic processGO:00105631840.011
protein modification by small protein conjugationGO:00324461870.011
cytokine mediated signaling pathwayGO:00192211150.011
asymmetric neuroblast divisionGO:005505910.011
regulation of peptide transportGO:0090087910.011
positive regulation of reactive oxygen species metabolic processGO:2000379110.010
heart morphogenesisGO:00030071780.010
regulation of actin nucleationGO:005112540.010
transcription from rna polymerase iii promoterGO:000638330.010
macromolecule methylationGO:00434141200.010
Mouse
amide transportGO:00428861380.010
mechanoreceptor differentiationGO:0042490670.010
purine ribonucleoside triphosphate metabolic processGO:00092052200.010
transmission of nerve impulseGO:0019226760.010
lipid biosynthetic processGO:00086101790.010
multicellular organismal signalingGO:0035637910.010
reactive oxygen species biosynthetic processGO:190340980.010
microtubule based processGO:00070172360.010
regulation of nlrp3 inflammasome complex assemblyGO:190022540.010
viral transcriptionGO:001908330.010
cognitionGO:00508901490.010
regulation of transcription from rna polymerase iii promoterGO:000635920.010
regulation of ras gtpase activityGO:0032318880.010
fatty acid metabolic processGO:00066311210.010
skeletal system developmentGO:00015013560.010
gliogenesisGO:00420631410.010

Irf3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.018
disease of anatomical entityDOID:700.018
immune system diseaseDOID:291400.015
central nervous system diseaseDOID:33100.011